Optical Lattice Simulations of Correlated Fermions

DTIC Science & Technology

2013-10-04

Zhang, Xiaopeng Li, W. Vincent Liu. Stripe , checkerboard, and liquid-crystal ordering from anisotropic p-orbital Fermi surfaces in optical lattices...Meeting "The Role of Interactions in Disorder Induced Damping of Dipole Oscillations of a Bose-Einstein Condensate", S. Pollack, APS March Meeting...Rev. A 85, 043603 (2012)], and also worked out the diffusive transport behavior of the polarized Fermi gas, including heat transport, spin Seebeck

Relativistic theory of nuclear spin-rotation tensor with kinetically balanced rotational London orbitals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiao, Yunlong; Zhang, Yong; Liu, Wenjian, E-mail: liuwjbdf@gmail.com

2014-10-28

Both kinetically balanced (KB) and kinetically unbalanced (KU) rotational London orbitals (RLO) are proposed to resolve the slow basis set convergence in relativistic calculations of nuclear spin-rotation (NSR) coupling tensors of molecules containing heavy elements [Y. Xiao and W. Liu, J. Chem. Phys. 138, 134104 (2013)]. While they perform rather similarly, the KB-RLO Ansatz is clearly preferred as it ensures the correct nonrelativistic limit even with a finite basis. Moreover, it gives rise to the same “direct relativistic mapping” between nuclear magnetic resonance shielding and NSR coupling tensors as that without using the London orbitals [Y. Xiao, Y. Zhang, andmore » W. Liu, J. Chem. Theory Comput. 10, 600 (2014)].« less

Cation coordination reactions on nanocrystals: surface/interface, doping control and advanced photocatalysis applications (Conference Presentation)

NASA Astrophysics Data System (ADS)

Zhang, Jiatao

2016-10-01

Abstract: Including the shape and size effect, the controllable doping, hetero-composite and surface/interface are the prerequisite of colloidal nanocrystals for exploring their optoelectronic properties, such as fluorescence, plasmon-exciton coupling, efficient electron/hole separation, and enhanced photocatalysis applications. By controlling soft acid-base coordination reactions between cation molecular complexes and colloidal nanocrystals, we showed that chemical thermodynamics could drive nanoscale monocrystalline growth of the semiconductor shell on metal nano-substrates and the substitutional heterovalent doping in semiconductor nanocrystals. We have demonstrated evolution of relative position of Au and II-VI semiconductor in Au-Semi from symmetric to asymmetric configuration, different phosphines initiated morphology engineering, oriented attachment of quantum dots into micrometer nanosheets with synergistic control of surface/interface and doing, which can further lead to fine tuning of plasmon-exciton coupling. Therefore, different hydrogen photocatalytic performance, Plasmon enhanced photocatalysis properties have been achieved further which lead to the fine tuning of plasmon-exciton coupling. Substitutional heterovalent doping here enables the tailoring of optical, electronic properties and photocatalysis applications of semiconductor nanocrystals because of electronic impurities (p-, n-type doping) control. References: (1) J. Gui, J. Zhang*, et al. Angew. Chem. Int. Ed. 2015, 54, 3683. (2) Q. Zhao, J. Zhang*, etc., Adv. Mater. 2014, 26, 1387. (3) J. Liu, Q. Zhao, S. G. Wang*, J. Zhang*, etc., Adv. Mater. 2015, 27-2753-2761. (4) H. Qian, J. Zhang*, etc., NPG Asia Mater. (2015) 7, e152. (5) M. Ji, M. Xu, etc., J. Zhang*, Adv. Mater. 2016, in proof. (6) S. Yu, J. T. Zhang, Y. Tang, M. Ouyang*, Nano Lett. 2015, 15, 6282-6288. (7) J. Zhang, Y. Tang, K. Lee and M. Ouyang*, Science 2010, 327, 1634. (8) J. Zhang, Y. Tang, K. Lee, M. Ouyang*, Nature 2010, 466, 91.

A revision of dragon millipedes I: genus Desmoxytes Chamberlin, 1923, with the description of eight new species (Diplopoda, Polydesmida, Paradoxosomatidae)

PubMed Central

Srisonchai, Ruttapon; Enghoff, Henrik; Likhitrakarn, Natdanai; Panha, Somsak

2018-01-01

Abstract The dragon millipede genus Desmoxytes s.l. is split into five genera, based on morphological characters and preliminary molecular phylogenetic analyses. The present article includes a review of Desmoxytes s.s., while future articles will deal with Hylomus Cook and Loomis, 1924 and three new genera which preliminarily are referred to as the ‘acantherpestes’, ‘gigas’, and ‘spiny’ groups. Diagnostic morphological characters of each group are discussed. Hylomus is resurrected as a valid genus and the following 33 species are assigned to it: H. asper (Attems, 1937), comb. n., H. cattienensis (Nguyen, Golovatch & Anichkin, 2005), comb. n., H. cervarius (Attems, 1953), comb. n., H. cornutus (Zhang & Li, 1982), comb. n., H. draco Cook & Loomis, 1924, stat. rev., H. enghoffi (Nguyen, Golovatch & Anichkin, 2005), comb. n., H. eupterygotus (Golovatch, Li, Liu & Geoffroy, 2012), comb. n., H. getuhensis (Liu, Golovatch & Tian, 2014), comb. n., H. grandis (Golovatch, VandenSpiegel & Semenyuk, 2016), comb. n., H. hostilis (Golovatch & Enghoff, 1994), comb. n., H. jeekeli (Golovatch & Enghoff, 1994), comb. n., H. lingulatus (Liu, Golovatch & Tian, 2014), comb. n., H. laticollis (Liu, Golovatch & Tian, 2016), comb. n., H. longispinus (Loksa, 1960), comb. n., H. lui (Golovatch, Li, Liu & Geoffroy, 2012), comb. n., H. minutuberculus (Zhang, 1986), comb. n., H. nodulosus (Liu, Golovatch & Tian, 2014), comb. n., H. parvulus (Liu, Golovatch & Tian, 2014), comb. n., H. phasmoides (Liu, Golovatch & Tian, 2016), comb. n., H. pilosus (Attems, 1937), comb. n., H. proximus (Nguyen, Golovatch & Anichkin, 2005), comb. n., H. rhinoceros (Likhitrakarn, Golovatch & Panha, 2015), comb. n., H. rhinoparvus (Likhitrakarn, Golovatch & Panha, 2015), comb. n., H. scolopendroides (Golovatch, Geoffroy & Mauriès, 2010), comb. n., H. scutigeroides (Golovatch, Geoffroy & Mauriès, 2010), comb. n., H. similis (Liu, Golovatch & Tian, 2016), comb. n., H. simplex (Golovatch, VandenSpiegel & Semenyuk, 2016), comb. n., H. simplipodus (Liu, Golovatch & Tian, 2016), comb. n., H. specialis (Nguyen, Golovatch & Anichkin, 2005), comb. n., H. spectabilis (Attems, 1937), comb. n., H. spinitergus (Liu, Golovatch & Tian, 2016), comb. n., H. spinissimus (Golovatch, Li, Liu & Geoffroy, 2012), comb. n. and H. variabilis (Liu, Golovatch & Tian, 2016), comb. n. Desmoxytes s.s. includes the following species: D. breviverpa Srisonchai, Enghoff & Panha, 2016; D. cervina (Pocock,1895); D. delfae (Jeekel, 1964); D. des Srisonchai, Enghoff & Panha, 2016; D. pinnasquali Srisonchai, Enghoff & Panha, 2016; D. planata (Pocock, 1895); D. purpurosea Enghoff, Sutcharit & Panha, 2007; D. takensis Srisonchai, Enghoff & Panha, 2016; D. taurina (Pocock, 1895); D. terae (Jeekel, 1964), all of which are re-described based mainly on type material. Two new synonyms are proposed: Desmoxytes pterygota Golovatch & Enghoff, 1994, syn. n. (= Desmoxytes cervina (Pocock, 1895)), Desmoxytes rubra Golovatch & Enghoff, 1994, syn. n. (= Desmoxytes delfae (Jeekel, 1964)). Six new species are described from Thailand: D. aurata Srisonchai, Enghoff & Panha, sp. n., D. corythosaurus Srisonchai, Enghoff & Panha, sp. n., D. euros Srisonchai, Enghoff & Panha, sp. n., D. flabella Srisonchai, Enghoff & Panha, sp. n., D. golovatchi Srisonchai, Enghoff & Panha, sp. n., D. octoconigera Srisonchai, Enghoff & Panha, sp. n., as well as one from Malaysia: D. perakensis Srisonchai, Enghoff & Panha, sp. n., and one from Myanmar: D. waepyanensis Srisonchai, Enghoff & Panha, sp. n. The species can mostly be easily distinguished by gonopod structure in combination with other external characters; some cases of particularly similar congeners are discussed. All species of Desmoxytes s.s. seem to be endemic to continental Southeast Asia (except the ‘tramp’ species D. planata). Some biological observations (relationship with mites, moulting) are recorded for the first time. Complete illustrations of external morphological characters, an identification key, and distribution maps of all species are provided. PMID:29875597

A revision of dragon millipedes I: genus Desmoxytes Chamberlin, 1923, with the description of eight new species (Diplopoda, Polydesmida, Paradoxosomatidae).

PubMed

Srisonchai, Ruttapon; Enghoff, Henrik; Likhitrakarn, Natdanai; Panha, Somsak

2018-01-01

The dragon millipede genus Desmoxytes s.l. is split into five genera, based on morphological characters and preliminary molecular phylogenetic analyses. The present article includes a review of Desmoxytes s.s., while future articles will deal with Hylomus Cook and Loomis, 1924 and three new genera which preliminarily are referred to as the ' acantherpestes ', ' gigas ', and ' spiny ' groups. Diagnostic morphological characters of each group are discussed. Hylomus is resurrected as a valid genus and the following 33 species are assigned to it: H. asper (Attems, 1937), comb. n. , H. cattienensis (Nguyen, Golovatch & Anichkin, 2005), comb. n. , H. cervarius (Attems, 1953), comb. n. , H. cornutus (Zhang & Li, 1982), comb. n. , H. draco Cook & Loomis, 1924, stat. rev. , H. enghoffi (Nguyen, Golovatch & Anichkin, 2005), comb. n. , H. eupterygotus (Golovatch, Li, Liu & Geoffroy, 2012), comb. n. , H. getuhensis (Liu, Golovatch & Tian, 2014), comb. n. , H. grandis (Golovatch, VandenSpiegel & Semenyuk, 2016), comb. n. , H. hostilis (Golovatch & Enghoff, 1994), comb. n. , H. jeekeli (Golovatch & Enghoff, 1994), comb. n. , H. lingulatus (Liu, Golovatch & Tian, 2014), comb. n. , H. laticollis (Liu, Golovatch & Tian, 2016), comb. n. , H. longispinus (Loksa, 1960), comb. n. , H. lui (Golovatch, Li, Liu & Geoffroy, 2012), comb. n. , H. minutuberculus (Zhang, 1986), comb. n. , H. nodulosus (Liu, Golovatch & Tian, 2014), comb. n. , H. parvulus (Liu, Golovatch & Tian, 2014), comb. n. , H. phasmoides (Liu, Golovatch & Tian, 2016), comb. n. , H. pilosus (Attems, 1937), comb. n. , H. proximus (Nguyen, Golovatch & Anichkin, 2005), comb. n. , H. rhinoceros (Likhitrakarn, Golovatch & Panha, 2015), comb. n. , H. rhinoparvus (Likhitrakarn, Golovatch & Panha, 2015), comb. n. , H. scolopendroides (Golovatch, Geoffroy & Mauriès, 2010), comb. n. , H. scutigeroides (Golovatch, Geoffroy & Mauriès, 2010), comb. n. , H. similis (Liu, Golovatch & Tian, 2016), comb. n. , H. simplex (Golovatch, VandenSpiegel & Semenyuk, 2016), comb. n. , H. simplipodus (Liu, Golovatch & Tian, 2016), comb. n. , H. specialis (Nguyen, Golovatch & Anichkin, 2005), comb. n. , H. spectabilis (Attems, 1937), comb. n. , H. spinitergus (Liu, Golovatch & Tian, 2016), comb. n. , H. spinissimus (Golovatch, Li, Liu & Geoffroy, 2012), comb. n. and H. variabilis (Liu, Golovatch & Tian, 2016), comb. n. Desmoxytes s.s. includes the following species: D. breviverpa Srisonchai, Enghoff & Panha, 2016; D. cervina (Pocock,1895); D. delfae (Jeekel, 1964); D. des Srisonchai, Enghoff & Panha, 2016; D. pinnasquali Srisonchai, Enghoff & Panha, 2016; D. planata (Pocock, 1895); D. purpurosea Enghoff, Sutcharit & Panha, 2007; D. takensis Srisonchai, Enghoff & Panha, 2016; D. taurina (Pocock, 1895); D. terae (Jeekel, 1964), all of which are re-described based mainly on type material. Two new synonyms are proposed: Desmoxytes pterygota Golovatch & Enghoff, 1994, syn. n. (= Desmoxytes cervina (Pocock, 1895)), Desmoxytes rubra Golovatch & Enghoff, 1994, syn. n. (= Desmoxytes delfae (Jeekel, 1964)). Six new species are described from Thailand: D. aurata Srisonchai, Enghoff & Panha, sp. n. , D. corythosaurus Srisonchai, Enghoff & Panha, sp. n. , D. euros Srisonchai, Enghoff & Panha, sp. n. , D. flabella Srisonchai, Enghoff & Panha, sp. n. , D. golovatchi Srisonchai, Enghoff & Panha, sp. n. , D. octoconigera Srisonchai, Enghoff & Panha, sp. n. , as well as one from Malaysia: D. perakensis Srisonchai, Enghoff & Panha, sp. n. , and one from Myanmar: D. waepyanensis Srisonchai, Enghoff & Panha, sp. n. The species can mostly be easily distinguished by gonopod structure in combination with other external characters; some cases of particularly similar congeners are discussed. All species of Desmoxytes s.s. seem to be endemic to continental Southeast Asia (except the 'tramp' species D. planata ). Some biological observations (relationship with mites, moulting) are recorded for the first time. Complete illustrations of external morphological characters, an identification key, and distribution maps of all species are provided.

Workshop on Aerospace Materials for Extreme Environments

DTIC Science & Technology

2009-12-01

Materials for Titanium Alloys Machining Ukraine Volodymyr Filipov Influence of Lattice Parameter Mismatch between Fibers and Matrix on Structure and...on your own 1:00 pm Alina Ievdokymova ZrBi2-Based Tool Materials for Titanium Alloys Machining 1:30 pm Donna Ballard and Don Weaver Processing of...C.K. Gren, T.P. Hanusa, "Deposition of Alumina From Dimethylaluminum Isopropoxide " Ken Sandhage D. Lipke, Y. Zhang, Y. Liu, B. Church, and K

Innovative T Cell-Targeted Therapy for Ovarian Cancer

DTIC Science & Technology

2013-10-01

curative.23 In contrast, long term survivorship of patients following allogeneic TCRαβ-depleted hematopoietic stem -cell transplantation (HSCT) was...receptors and steroid receptors. Stem cells 1996; 14(6): 632-41. 40. Lai D, Wang F, Chen Y, Wang C, Liu S, Lu B et al. Human ovarian cancer stem ...leukemia stem cells and eliminate AML. Manuscript in preparation. 46. Zhang M, Maiti S, Bernatchez C, Huls H, Rabinovich B, Champlin RE, Vence LM, Hwu P

Validity of the site-averaging approximation for modeling the dissociative chemisorption of H{sub 2} on Cu(111) surface: A quantum dynamics study on two potential energy surfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Tianhui; Fu, Bina, E-mail: bina@dicp.ac.cn, E-mail: zhangdh@dicp.ac.cn; Zhang, Dong H., E-mail: bina@dicp.ac.cn, E-mail: zhangdh@dicp.ac.cn

A new finding of the site-averaging approximation was recently reported on the dissociative chemisorption of the HCl/DCl+Au(111) surface reaction [T. Liu, B. Fu, and D. H. Zhang, J. Chem. Phys. 139, 184705 (2013); T. Liu, B. Fu, and D. H. Zhang, J. Chem. Phys. 140, 144701 (2014)]. Here, in order to investigate the dependence of new site-averaging approximation on the initial vibrational state of H{sub 2} as well as the PES for the dissociative chemisorption of H{sub 2} on Cu(111) surface at normal incidence, we carried out six-dimensional quantum dynamics calculations using the initial state-selected time-dependent wave packet approach, withmore » H{sub 2} initially in its ground vibrational state and the first vibrational excited state. The corresponding four-dimensional site-specific dissociation probabilities are also calculated with H{sub 2} fixed at bridge, center, and top sites. These calculations are all performed based on two different potential energy surfaces (PESs). It is found that the site-averaging dissociation probability over 15 fixed sites obtained from four-dimensional quantum dynamics calculations can accurately reproduce the six-dimensional dissociation probability for H{sub 2} (v = 0) and (v = 1) on the two PESs.« less

Promoting Secondary Analysis of Electronic Medical Records in China: Summary of the PLAGH-MIT Critical Data Conference and Health Datathon.

PubMed

Li, Peiyao; Xie, Chen; Pollard, Tom; Johnson, Alistair Edward William; Cao, Desen; Kang, Hongjun; Liang, Hong; Zhang, Yuezhou; Liu, Xiaoli; Fan, Yong; Zhang, Yuan; Xue, Wanguo; Xie, Lixin; Celi, Leo Anthony; Zhang, Zhengbo

2017-11-14

Electronic health records (EHRs) have been widely adopted among modern hospitals to collect and track clinical data. Secondary analysis of EHRs could complement the traditional randomized control trial (RCT) research model. However, most researchers in China lack either the technical expertise or the resources needed to utilize EHRs as a resource. In addition, a climate of cross-disciplinary collaboration to gain insights from EHRs, a crucial component of a learning healthcare system, is not prevalent. To address these issues, members from the Massachusetts Institute of Technology (MIT) and the People's Liberation Army General Hospital (PLAGH) organized the first clinical data conference and health datathon in China, which provided a platform for clinicians, statisticians, and data scientists to team up and address information gaps in the intensive care unit (ICU). ©Peiyao Li, Chen Xie, Tom Pollard, Alistair Edward William Johnson, Desen Cao, Hongjun Kang, Hong Liang, Yuezhou Zhang, Xiaoli Liu, Yong Fan, Yuan Zhang, Wanguo Xue, Lixin Xie, Leo Anthony Celi, Zhengbo Zhang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 14.11.2017.

Photoacoustic Imaging of Epilepsy

DTIC Science & Technology

2013-04-01

mouse brain with the skin and skull intact,” Opt. Lett. 28(19), 1739–1741 (2003). 5. Q. Zhang, Z. Liu, P. R. Carney, Z. Yuan, H. Chen, S. N. Roper, and...imaging at centimeter scale depths. To date PAT has been applied to the detection of breast cancer, skin cancer and osteoarthritis in humans [1–3...the hemodynamic changes and reveal the 3D structures in the rat brain. Two small rats (~40g) were imaged with intact skull and skin but hairs on the

Ultra-Flexible, Invisible Thin-Film Transistors Enabled by Amorphous Metal Oxide/Polymer Channel Layer Blends

DTIC Science & Technology

2015-02-25

all the In 2 O 3 : x %PVP blends, where the polymer chains disrupt oxide lattice forma - tion at the nanoscale grain level rather than at the atomic...oxidative stability. [ 51,52 ] This result can be qualitatively ascribed to the endothermic M–O–M lattice forma - tion acting as heat absorber and the ultra... Irie , M. Komiyama , H. Yui , Supramol. Sci. 1998 , 5 , 411 . [40] D. B. Buchholz , J. Liu , T. J. Marks , M. Zhang , R. P. Chang

Characterizing SHP2 as a Novel Therapeutic Target in Breast Cancer

DTIC Science & Technology

2012-02-01

50(12), 2339-56. doi:10.1021/bi1014453 Zhang, X., He, Y., Liu, S., Yu, Z., Jiang, Z. X., Yang, Z., Dong, Y., et al. (2010). Salicylic Acid Based...Overall, what we have found so far has been surprising, with the data suggesting that the presence of a -2 acidic residue in the substrate peptide...helped to refine the initial docking poses, with the initial hypothesis being that the pY -1 and -4 position acidic amino acids will bind a pair of

A Highly Aromatic and Sulfonated Ionomer for High Elastic Modulus Ionic Polymer Membrane Micro-Actuators

DTIC Science & Technology

2012-05-01

fluorophenyl)sulfone (DPA-PS:BP) is investigated for ionic polymer actuators. The uniqueness of DPA-PS:BP is that it can have a high ionic liquid (IL... ionic liquid Q M Zhang, Gokhan Hatipoglu, Yang Liu, Ran Zhao, Mitra Yoonessi, Dean M Tigelaar, Srinivas Tadigadapa Virginia Polytechnic Institute...DPA-PS:BP) is investigated for ionic polymer actuators. The uniqueness of DPA-PS:BP is that it can have a high ionic liquid (IL) uptake and

Development of Sesquioxide Ceramic for High Energy Lasers

DTIC Science & Technology

2015-05-25

CSJ308 , Mutsuno, Atsuta- ku Nagoya 456-0023 Japan 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING/MONITORING AGENCY NAME...Labo Co., Ltd.,1-2-19-CSJ308 , Mutsuno, Atsuta- ku ,Nagoya 456-0023,Japan,NA,NA 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING/MONITORING...Huang, D. Shen , J. Zhang, H. Chen, Y. Wang, X. Liu, D. Tang, “Room Temperature Continuous-wave Laser Performance of LD Pumped Er:Lu2O3 and Er:Y2O3

First Public Report on the Military Academy Chinese People’s Liberation Army Military Pictures Collection (Selected Articles),

DTIC Science & Technology

1986-10-10

Cooperation, by Liu Jienyang, Zhao Rueishan, Ze Fu .......... 35 > A Visit to the Institute of Guided Missile Technology, by Zhang Juzheng, Li Weiliang...4,. *1 .4 9- -I. .p *. .4 I-.- a. S.... .4 11 l.a. 9-.4 *49.4*~*9*~. ° - S’: Key: (1) Analyst Li Xien studies techniques hard in the field in...leader Chairman Hua, Vice Chairmen Ye Jianying , Deng Xiao- ping, Wang Dongxing and other leaders of the party, state and militaryarrived at the

Synthesis of Si Nanowires for an Anode Material of Li Batteries

DTIC Science & Technology

2007-12-04

Zhou, H. Li, H.P. Sun , D.P. Yu, Y.Q. Wang, X.J. Huang, L.Q. Chen, Z. Zhang, Appl. Phys. Lett. 75 (16) (1999) 2447 6. A.M. Wilson, B.M. Way, J.R. Dahn...Y. Liu, Electrochem. Commun. 5 (2003) 165 12. Tatsuo Umeno, Kenji Fukuda, Hongyu Wang, Nikolay Dimov, Takashi Iwao, Masaki Yoshio, Chem. Lett...Hansu Kim, Junghee Choi, Hun-Joon Sohn and Tak Kang, J. Electrochem. Soc. 146 (12) (1999) 4401 18. G.X. Wang, L. Sun , D.H. Bradhurst, S. Zhong, S.X. Dou

Comparison of the Side Populations in Pretreatment and Postrelapse Neuroblastoma Cell Lines

DTIC Science & Technology

2010-08-01

396–401. [15] Hansford LM, McKee AE, Zhang L, George RE, Gerstle JT, Thorner PS, Smith KM, Look AT, Yeger H, Miller FD, et al. (2007). Neuroblastoma...Acad Sci USA 103, 11154–11159. [32] Wu C, Wei Q , Utomo V, Nadesan P, Whetstone H, Kandel R, Wunder JS, and Alman BA (2007). Side population cells...Jeter CR, Badeaux M, Choy G, Chandra D, Patrawala L, Liu C, Calhoun- Davis T, Zaehres H, Daley GQ, and Tang DG (2009). Functional evidence that the

Volumetric T-spline Construction Using Boolean Operations

DTIC Science & Technology

2013-07-01

SUBTITLE Volumetric T-spline Construction Using Boolean Operations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...Acknowledgements The work of L. Liu and Y. Zhang was supported by ONR-YIP award N00014- 10-1-0698 and an ONR Grant N00014-08-1-0653. T. J.R. Hughes was sup- 16...T-spline Construction Using Boolean Operations 17 ported by ONR Grant N00014-08-1-0992, NSF GOALI CMI-0700807/0700204, NSF CMMI-1101007 and a SINTEF

Solid T-spline Construction from Boundary Triangulations with Arbitrary Genus Topology

DTIC Science & Technology

2012-04-01

Topology 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...Acknowledgements Y. Zhang, W. Wang and L. Liu were supported in part by ONR Grant N00014-08-1-0653. T. J.R. Hughes was sup- ported by ONR Grant N00014-08-1-0992, NSF...blue) and one pillowed layer (magenta); and (h) the isogeometric analysis result. 11 0700807/0700204, NSF CMMI-1101007 and a grant from SINTEF. The

Association Study of Serotonin Transporter Gene Polymorphisms with Obstructive Sleep Apnea Syndrome in Chinese Han Population

PubMed Central

Yue, Weihua; Liu, Huiguo; Zhang, Jishui; Zhang, Xianghui; Wang, Xiaoping; Liu, Tieqiao; Liu, Pozi; Hao, Wei

2008-01-01

Background: Since the serotonin (5-HT) is associated with circadian rhythm and breathing regulation, the serotonin transporter (5-HTT), which plays an important role in serotoninergic transmission, might be a strong candidate gene in the pathogenesis of obstructive sleep apnea syndrome (OSAS). Objective: To investigate the association of 5-HTT gene polymorphisms with OSAS and clinical characteristics. Methods: We genotyped the 5-HTT gene linked polymorphic region (5-HTTLPR) and a variable number of tandem repeats at intron 2 (STin2.VNTR) in 254 OSAS patients and 338 healthy controls in Chinese Han population. Results: In total sample, the 10-repeat allele of STin2.VNTR was significantly associated with OSAS (P = 0.007, OR = 1.72, 95% CI = 1.15~2.58), but no association was found in 5-HTTLPR. In male subjects, both polymorphisms showed significant association with OSAS (Allele L: P = 0.005, OR = 1.44, 95% CI = 1.11 to 1.87; Allele 10: P = 0.002, OR = 1.94, 95% CI = 1.26 to 3.00). Two haplotypes, S-12 and L-10, constructed by the above polymorphisms also revealed significant associations with OSAS (global P-values were 0.020 for total sample and 0.0006 for male subjects, respectively). Male patients carrying the haplotype S-12 showed a significantly lower apnea / hypopnea index (AHI), depressive factor, plasma 5-HT level and 5-hydroxyindolacetic acid (5-HIAA) levels, but higher episodic memory, when compared with non-S-12 carriers (P < 0.05). However, no significant differences were found in excessive daytime sleepiness or other psychological function across haplotype carriers (P > 0.05). Conclusions: These findings support that 5-HTT gene may be involved in susceptibility to OSAS, especially with sex-dependent effect. Citation: Yue W; Liu H; Zhang J; Zhang X; Wang X; Liu T; Liu P; Hao W. Association study of serotonin transporter gene polymorphisms with obstructive sleep apnea syndrome in chinese han population. SLEEP 2008;31(11):1535–1541. PMID:19014073

Translocation and accumulation of trace metals from the rhizosphere to the tomato and topinambur plants in a contaminated area of South Italy

NASA Astrophysics Data System (ADS)

Papa, Stefania; Bartoli, Giovanni; Álvarez-Romero, Marta; Zornoza, Raúl; Carillo, Petronia; Fioretto, Antonietta

2017-04-01

According to a survey of the Italian Environmental Monitoring Agency (ARPA), there are different critical sites in Campania region (South Italy) (e.i. legal or illegal landfills, countryside lands, abandoned farms, parking lots and regular streets). Literature data show that about half of the lead, cadmium and mercury contents, ingested through food, is due to the plant products (fruit, vegetables and grains) (Kachenko and Singh 2006; Liu et al 2012; Chang et al 2014; Wong et al 2002). In the health protection programs, the knowledge of heavy metals translocation from soils to plants used as food are very important with research on metal uptake by plants of food interest cultivated in contaminated soils. The goal of this work was to evaluate the translocation and accumulation of trace metals from the rhizosphere to the different parts of the plant (roots, stems, leaves, fruit) of Topinambur (Helianthus tuberosus) and tomato (Solanum lycopersicum) sampled in the coast area of Castel Volturno (Campania region, South Italy). This area is one of the critical sites according to a survey of the Environmental Monitoring Agency ARPA. In addition to these measures, malondialdehyde (MDA) activity was assayed to evaluate the stress state of the plant. The results showed that the trace metals concentration determinated in different organs of each species studied were more present in the roots than the other plant's parts, suggesting a probable block at root level. The only exception were Cu and Hg in tomato and topinambur plants respectively, that were mainly present in the leaves. The metals block at the root induced no alteration of MDA. However, the correlation between this activity and Cd, Pb, V and Hg seemed to attest to a possible synergy. Keywords: "Helianthus tuberosus", "Solanum lycopersicum", trace metal, traslocation Reference -Kachenko AG, Singh B, 2006 Heavy Metals Contamination in Vegetables Grown in Urban and Metal Smelter Contaminated Sites in Australia. Water, Air, and Soil Pollution 169: 101-123; -Liu L, Hu LL, Tang JJ, Li YF, Zhang Q, Chen X. 2012. Food safety assessment of planting patterns of four vegetable-type crops grown in soil contaminated by electronic waste activities. Journal of Environmental Management. 93(1):22-30. doi:10.1016/j.jenvman.2011.08.021 -Chang C. Y., Yu H. Y., Chen J. J., L i F. B., Zhang H. H., Liu C. P., 2014. Accumulation of heavy metals in leaf vegetables from agricultural soils and associated potential health risks in the Pearl River Delta, South China Environ. Monit. Assess. 2014; 186(3): 1547-1560. -Wong SC, Li XD, Zhang G, Qi SH, MinYS, 2002 Heavy metals in agricultural soils of the Pearl River Delta, South China Environmental Pollution, 119 (1) 33-4

Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.

PubMed

Yan, Meiping; Zhang, Xinhua; Chen, Ao; Gu, Wei; Liu, Jie; Ren, Xiaojiao; Zhang, Jianping; Wu, Xiaoxiong; Place, Aaron T; Minshall, Richard D; Liu, Guoquan

2017-11-01

Intercellular adhesion molecule-1 (ICAM-1) mediates the firm adhesion of leukocytes to endothelial cells and initiates subsequent signaling that promotes their transendothelial migration (TEM). Vascular endothelial (VE)-cadherin plays a critical role in endothelial cell-cell adhesion, thereby controlling endothelial permeability and leukocyte transmigration. This study aimed to determine the molecular signaling events that originate from the ICAM-1-mediated firm adhesion of neutrophils that regulate VE-cadherin's role as a negative regulator of leukocyte transmigration. We observed that ICAM-1 interacts with Src homology domain 2-containing phosphatase-2 (SHP-2), and SHP-2 down-regulation via silencing of small interfering RNA in endothelial cells enhanced neutrophil adhesion to endothelial cells but inhibited neutrophil transmigration. We also found that VE-cadherin associated with the ICAM-1-SHP-2 complex. Moreover, whereas the activation of ICAM-1 leads to VE-cadherin dissociation from ICAM-1 and VE-cadherin association with actin, SHP-2 down-regulation prevented ICAM-1-VE-cadherin association and promoted VE-cadherin-actin association. Furthermore, SHP-2 down-regulation in vivo promoted LPS-induced neutrophil recruitment in mouse lung but delayed neutrophil extravasation. These results suggest that SHP-2- via association with ICAM-1-mediates ICAM-1-induced Src activation and modulates VE-cadherin switching association with ICAM-1 or actin, thereby negatively regulating neutrophil adhesion to endothelial cells and enhancing their TEM.-Yan, M., Zhang, X., Chen, A., Gu, W., Liu, J., Ren, X., Zhang, J., Wu, X., Place, A. T., Minshall, R. D., Liu, G. Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction. © FASEB.

Reply to Comment: 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'.

PubMed

Ma, Dinglong; Liu, Jing; Qi, Jinyi; Marcu, Laura

2017-02-21

In this response we underscore that the instrumentation described in the original publication (Liu et al 2012 Phys. Med. Biol. 57 843-65) was based on pulse-sampling technique, while the comment by Zhang et al is based on the assumption that a time-correlated single photon counting (TCSPC) instrumentation was used. Therefore the arguments made in the comment are not applicable to the noise model reported by Liu et al. As reported in the literature (Lakowicz 2006 Principles of Fluorescence Spectroscopy (New York: Springer)), while in the TCSPC the experimental noise can be estimated from Poisson statistics, such an assumption is not valid for pulse-sampling (transient recording) techniques. To further clarify this aspect, we present here a comprehensive noise model describing the signal and noise propagation of the pulse sampling time-resolved fluorescence detection. Experimental data recorded in various conditions are analyzed as a case study to demonstrate the noise model of our instrumental system. In addition, regarding the statement of correcting equation (3) in Liu et al (2012 Phys. Med. Biol. 57 843-65), the notation of discrete time Laguerre function in the original publication was clear and consistent with literature conventions (Marmarelis 1993 Ann. Biomed. Eng. 21 573-89, Westwick and Kearney 2003 Identification of Nonlinear Physiological Systems (Hoboken, NJ: Wiley)). Thus, it does not require revision.

Reply to Comment: ‘A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion’

NASA Astrophysics Data System (ADS)

Ma, Dinglong; Liu, Jing; Qi, Jinyi; Marcu, Laura

2017-02-01

In this response we underscore that the instrumentation described in the original publication (Liu et al 2012 Phys. Med. Biol. 57 843-65) was based on pulse-sampling technique, while the comment by Zhang et al is based on the assumption that a time-correlated single photon counting (TCSPC) instrumentation was used. Therefore the arguments made in the comment are not applicable to the noise model reported by Liu et al. As reported in the literature (Lakowicz 2006 Principles of Fluorescence Spectroscopy (New York: Springer)), while in the TCSPC the experimental noise can be estimated from Poisson statistics, such an assumption is not valid for pulse-sampling (transient recording) techniques. To further clarify this aspect, we present here a comprehensive noise model describing the signal and noise propagation of the pulse sampling time-resolved fluorescence detection. Experimental data recorded in various conditions are analyzed as a case study to demonstrate the noise model of our instrumental system. In addition, regarding the statement of correcting equation (3) in Liu et al (2012 Phys. Med. Biol. 57 843-65), the notation of discrete time Laguerre function in the original publication was clear and consistent with literature conventions (Marmarelis 1993 Ann. Biomed. Eng. 21 573-89, Westwick and Kearney 2003 Identification of Nonlinear Physiological Systems (Hoboken, NJ: Wiley)). Thus, it does not require revision.

Diamond Nucleation of Surfaces Using Carbon Clusters

DTIC Science & Technology

1993-05-01

8217 den lotafC 0, OAF e ol (*(.Pt 01If CZ.,,C :A 4 C.d,^; flt.0"$ j .n to, thl 0..eftC TO 440?.NqtOn -44sca.’lie’l eon Ofttlo tt 0( tl O Af~tO o0V614...is used to keep the sample in place. The cap is made of either graphite, quartz, or boron nitride depending on the particular experiment. In this...John, P., Alvarez, M.M., Diederich, F., and Whetten, R.L., J. Phys. Chem. in press (1991). 40 44. Zhang, Q.L., 0’ Brien , S.C., Heath, J.R., Liu, Y

Deflected Propagation of Coronal Mass Ejections: One of the Key Issues in Space Weather Forecasting

NASA Astrophysics Data System (ADS)

Wang, Y.; Shen, C.; Zhuang, B.; Pan, Z.

2016-12-01

As the most important driver of severe space weather, coronal mass ejections (CMEs) and their geoeffectiveness have been studied intensively. Previous statistical studies have shown that not all the front-side halo CMEs are geoeffective, and not all non-recurrent geomagnetic storms can be tracked back to a CME. These phenomena may cause some failed predictions of the geoeffectiveness of CMEs. The recent notable event exhibiting such a failure was on 2015 March 15 when a fast CME originated from the west hemisphere. Space Weather Prediction Center (SWPC) of NOAA initially forecasted that the CME would at most cause a very minor geomagnetic disturbance labeled as G1. However, the CME produced the largest geomagnetic storm so far, at G4 level with the provisional Dst value of -223 nT, in the current solar cycle 24 [e.g., Kataoka et al., 2015; Wang et al., 2016]. Such an unexpected phenomenon naturally raises the first question for the forecasting of the geoeffectiveness of a CME, i.e., whether or not a CME will hit the Earth even though we know the source location and initial kinematic properties of the CME. A full understanding of the propagation trajectory, e.g., the deflected propagation, of a CME from the Sun to 1 AU is the key. With a few cases, we show the importance of the deflection effect in the space weather forecasting. An automated CME arrival forecasting system containing a deflected propagation model is presented. References:[1] Kataoka, R., D. Shiota, E. Kilpua, and K. Keika, Pileup accident hypothesis of magnetic storm on 17 March 2015, Geophys. Res. Lett., 42, 5155-5161, 2015.[2] Wang, Yuming, Quanhao Zhang, Jiajia Liu, Chenglong Shen, Fang Shen, Zicai Yang, T. Zic, B. Vrsnak, D. F. Webb, Rui Liu, S. Wang, Jie Zhang, Q. Hu, and B. Zhuang, On the Propagation of a Geoeffective Coronal Mass Ejection during March 15 - 17, 2015, J. Geophys. Res., accepted, doi:10.1002/2016JA022924, 2016.

Ascaridoid parasites infecting in the frequently consumed marine fishes in the coastal area of China: A preliminary investigation.

PubMed

Zhao, Wen-Ting; Lü, Liang; Chen, Hui-Xia; Yang, Yue; Zhang, Lu-Ping; Li, Liang

2016-04-01

Marine fishes represent the important components of the diet in the coastal areas of China and they are also natural hosts of various parasites. However, to date, little is known about the occurrence of ascaridoid parasites in the frequently consumed marine fishes in China. In order to determine the presence of ascaridoid parasites in the frequently consumed marine fishes in the coastal town Huizhou, Guangdong Province, China, 211 fish representing 45 species caught from the South China Sea (off Daya Gulf) were examined. Five species of ascaridoid nematodes at different developmental stages were detected in the marine fishes examined herein, including third-stage larva of Anisakis typica (Diesing, 1860), third and fourth-stage larvae of Hysterothylacium sp. IV-A of Shamsi, Gasser & Beveridge, 2013, adult and third-stage larvae of Hysterothylacium zhoushanense Li, Liu & Zhang, 2014, adults and third-stage larvae of Raphidascaris lophii (Wu, 1949) and adults of Raphidascaris longispicula Li, Liu & Zhang, 2012. The overall prevalence of infection is 18.0%. Of them, Hysterothylacium sp. IV-A with the highest prevalence (17.5%) and intensity (mean=14.6) of infection was the predominant species. The prevalence and intensity of A. typica were very low (1/211 of marine fish infected with an intensity of one parasite per fish). The morphological and molecular characterization of all nematode species was provided. A cladistic analysis based on ITS sequence was constructed in order to determine the phylogenetic relationships of these ascaridoid parasites obtained herein. The present study provided important information on the occurrence and diagnosis of ascaridoid nematodes in the commercially important marine fishes from the South China Sea. The low level of infection and the species composition of ascaridoid nematodes seem to indicate the presence of low risk of human anisakidosis when local population consumed these marine fishes examined herein. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

A THz plasmonics perfect absorber and Fabry-Perot cavity mechanism (Conference Presentation)

NASA Astrophysics Data System (ADS)

Zhou, Jiangfeng; Bhattarai, Khagendra; Silva, Sinhara; Jeon, Jiyeon; Kim, Junoh; Lee, Sang Jun; Ku, Zahyun

2016-10-01

The plasmonic metamaterial perfect absorber (MPA) is a recently developed branch of metamaterial which exhibits nearly unity absorption within certain frequency range.[1-6] The optically thin MPA possesses characteristic features of angular-independence, high Q-factor and strong field localization that have inspired a wide range of applications including electromagnetic wave absorption,[3, 7, 8] spatial[6] and spectral[5] modulation of light,[9] selective thermal emission,[9] thermal detecting[10] and refractive index sensing for gas[11] and liquid[12, 13] targets. In this work, we demonstrate a MPA working at terahertz (THz) regime and characterize it using an ultrafast THz time-domain spectroscopy (THz-TDS). Our study reveal an ultra-thin Fabry-Perot cavity mechanism compared to the impedance matching mechanism widely adopted in previous study [1-6]. Our results also shows higher-order resonances when the cavities length increases. These higher order modes exhibits much larger Q-factor that can benefit potential sensing and imaging applications. [1] C. M. Watts, X. L. Liu, and W. J. Padilla, "Metamaterial Electromagnetic Wave Absorbers," Advanced Materials, vol. 24, pp. 98-120, Jun 19 2012. [2] M. Hedayati, F. Faupel, and M. Elbahri, "Review of Plasmonic Nanocomposite Metamaterial Absorber," Materials, vol. 7, pp. 1221-1248, 2014. [3] N. I. Landy, S. Sajuyigbe, J. J. Mock, D. R. Smith, and W. J. Padilla, "Perfect metamaterial absorber," Physical Review Letters, vol. 100, p. 207402, May 23 2008. [4] H. R. Seren, G. R. Keiser, L. Cao, J. Zhang, A. C. Strikwerda, K. Fan, et al., "Optically Modulated Multiband Terahertz Perfect Absorber," Advanced Optical Materials, vol. 2, pp. 1221-1226, 2014. [5] D. Shrekenhamer, J. Montoya, S. Krishna, and W. J. Padilla, "Four-Color Metamaterial Absorber THz Spatial Light Modulator," Advanced Optical Materials, vol. 1, pp. 905-909, 2013. [6] S. Savo, D. Shrekenhamer, and W. J. Padilla, "Liquid Crystal Metamaterial Absorber Spatial Light Modulator for THz Applications," Advanced Optical Materials, vol. 2, pp. 275-279, 2014. [7] H. Tao, N. I. Landy, C. M. Bingham, X. Zhang, R. D. Averitt, and W. J. Padilla, "A metamaterial absorber for the terahertz regime: Design, fabrication and characterization," Optics Express, vol. 16, pp. 7181-7188, May 12 2008. [8] J. Hao, J. Wang, X. Liu, W. J. Padilla, L. Zhou, and M. Qiu, "High performance optical absorber based on a plasmonic metamaterial," Applied Physics Letters, vol. 96, p. 251104, 2010. [9] X. Liu, T. Tyler, T. Starr, A. F. Starr, N. M. Jokerst, and W. J. Padilla, "Taming the Blackbody with Infrared Metamaterials as Selective Thermal Emitters," Physical Review Letters, vol. 107, p. 045901, 07/18/ 2011. [10] T. Maier and H. Brückl, "Wavelength-tunable microbolometers with metamaterial absorbers," Optics Letters, vol. 34, pp. 3012-3014, 2009/10/01 2009. [11] A. Tittl, P. Mai, R. Taubert, D. Dregely, N. Liu, and H. Giessen, "Palladium-Based Plasmonic Perfect Absorber in the Visible Wavelength Range and Its Application to Hydrogen Sensing," Nano Letters, vol. 11, pp. 4366-4369, 2011/10/12 2011. [12] N. Liu, M. Mesch, T. Weiss, M. Hentschel, and H. Giessen, "Infrared Perfect Absorber and Its Application As Plasmonic Sensor," Nano Letters, vol. 10, pp. 2342-2348, Jul 2010. [13] G. H. Li, X. S. Chen, O. P. Li, C. X. Shao, Y. Jiang, L. J. Huang, et al., "A novel plasmonic resonance sensor based on an infrared perfect absorber," Journal of Physics D-Applied Physics, vol. 45, p. 205102, May 23 2012.

Progress in understanding the formation of fine particulate matter and ground-level ozone in Pearl River Delta region, China

NASA Astrophysics Data System (ADS)

Wang, Xuemei; Wang, Tao; Zheng, Junyu; Shao, Min; Wang, Xinming

2015-12-01

In the past three decades, the Pearl River Delta of China has been suffered from severe air pollution due to the rapid increase in energy consumption associated with industrialization and urbanization of the region. The number of hazy days, increased from below 20 days in a year before 1970, to more than 150 days a year during 1980 and 2000. The ground-level ozone levels have also on the rise, with hourly concentration of 160 ppbv being observed in Guangzhou and 201 ppbv in nearby Hong Kong (Zhang et al., 2008). The ozone pollution has been difficult to reduce even in air quality improvement program for the Guangzhou Asian Games (Liu et al., 2013).

Peer review statement

NASA Astrophysics Data System (ADS)

2012-11-01

All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the editors of the 26th IAHR Symposium on Hydraulic Machinery and Systems proceedings. Reviews were conducted by expert referees from the International Technical Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 26th IAHR Symposium on Hydraulic Machinery and Systems are: Yulin WU Tsinghua University China François AVELLAN EPFL-LMH Switzerland (principal) Xingqi LUO Xi'an University of Sci & Tech China Martin BÖHLE Kaiserslautern University Germany Gerard BOIS Arts et Métiers ParisTech France Luca D'AGOSTINO University of Pisa Italy Eduard EGUSQUIZA Polytechnical University Catalonia Spain Richard FISHER Voith Hydro Inc USA Regiane FORTES-PATELLA Institute Polytechnique de Grenoble France Aleksandar GAJIC University of Belgrade Serbia Wei YANG China Agriculture University China YinLu YOUNG University of Michigan USA Adrian LUNGU Dunarea de Jos University of Galati Romania Arpad FAY University of Miskolcz Hungary José GONZÁLEZ Universidad de Oviedo Spain Baoshan ZHU Tsinghua University China Hongxun CHEN Shanghai University China Chisachi KATO University of Tokyo Japan Zhenyue MA Dalian University of Sci & Tech China Honggang FAN Tsinghua University China François GUIBAULT Ecole Polytechnique de Montreal Canada Pengcheng GUO Xian University of Technology China Leqing WANG Zhejiang University China Toshiaki IKOHAGI Tohoku University Japan Jiandong YANG Wuhan University China Jianzhong ZHOU Huazhong University of Sci & Tech China Jinwei LI NULL China Rennian LI Lanzhou University of Sci & Tech China Houlin LIU NULL China Juan LIU Tsinghua University China Shuhong LIU Tsinghua University China Xianwu LUO Tsinghua University China Michihiro NISHI Tsinghua University China Peter PELZ Darmstadt University Germany František POCHYLY Brno University Czech Republic Rudolf SCHILLING Technische Universität München Germany Minguan YANG Jiangsu University China Smaine KOUIDRI Université Pierre et Marie Curie (Paris 6) France Kazuhiro TANAKA Kyushu Institute of Technology Japan Xuelin TANG Tsinghua University China Yoshinobu TSUJIMOTO Osaka University Japan Fujun WANG China Agriculture University China Guoyu WANG Beijing University of Sci & Tech China Wenwu SONG NULL China Zhengwei WANG Tsinghua University China Hongyuan XU Tsinghua University China Lefu XIAO NULL China Fan YANG Tsinghua University China Yuan ZHENG Hehai University China Zhigang ZUO Tsinghua University China Hongwu ZHU China Petroleum University China Lixiang ZHANG Yunnan University of Sci & Tech China Shengchang ZHANG Zhejiang University of Tech China

Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

NASA Astrophysics Data System (ADS)

Zhang, Y. P.; Liu, Yi; Luo, X. B.; Isobe, M.; Yuan, G. L.; Liu, Y. Q.; Hua, Y.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.

2014-05-01

A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team, Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Y. P., E-mail: zhangyp@swip.ac.cn; Liu, Yi; Yuan, G. L.

A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y.more » Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team , Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.« less

Implementing a warm cloud microphysics parameterization for convective clouds in NCAR CESM

NASA Astrophysics Data System (ADS)

Shiu, C.; Chen, Y.; Chen, W.; Li, J. F.; Tsai, I.; Chen, J.; Hsu, H.

2013-12-01

Most of cumulus convection schemes use simple empirical approaches to convert cloud liquid mass to rain water or cloud ice to snow e.g. using a constant autoconversion rate and dividing cloud liquid mass into cloud water and ice as function of air temperature (e.g. Zhang and McFarlane scheme in NCAR CAM model). There are few studies trying to use cloud microphysical schemes to better simulate such precipitation processes in the convective schemes of global models (e.g. Lohmann [2008] and Song, Zhang, and Li [2012]). A two-moment warm cloud parameterization (i.e. Chen and Liu [2004]) is implemented into the deep convection scheme of CAM5.2 of CESM model for treatment of conversion of cloud liquid water to rain water. Short-term AMIP type global simulations are conducted to evaluate the possible impacts from the modification of this physical parameterization. Simulated results are further compared to observational results from AMWG diagnostic package and CloudSAT data sets. Several sensitivity tests regarding to changes in cloud top droplet concentration (here as a rough testing for aerosol indirect effects) and changes in detrained cloud size of convective cloud ice are also carried out to understand their possible impacts on the cloud and precipitation simulations.

Retracted: Long-term copper toxicity in apple trees (Malus pumila Mill) and bioaccumulation in fruits.

PubMed

Sun, Bai-Ye; Kan, Shi-Hong; Zhang, Yan-Zong; Wu, Jun; Deng, Shi-Huai; Liu, Chun-Sheng; Yang, Gang

2010-01-15

The following article from Environmental Toxicology, 'Long-term Copper Toxicity in Apple Trees (Malus pumila Mill) and Bioaccumulation in Fruits' by Bai-Ye Sun, Shi- Hong Kan, Yan-Zong Zhang, Jun Wu, Shi-Huai Deng, Chun-Sheng Liu and Gang Yang, published online on January 15, 2010 in Wiley InterScience (www.interscience.wiley.com; DOI: 10.1002/tox.20565), has been retracted by agreement between the authors, the journal Editor in Chief, Dr. Paul Tchounwou, and Wiley Periodicals, Inc. The retraction has been agreed at the request of the authors due to overlap with 'Copper Toxicity and Bioaccumulation in Chinese Cabbage (Brassica pekinensis Rupr.)' by Zhi-Ting Xiong and Hai Wang, published in Environmental Toxicology, Volume 20, pages 188-194, 2005.

Taxonomic notes on Babinskaiidae from the Cretaceous Burmese amber, with the description of a new species (Insecta, Neuroptera).

PubMed

Hu, Jiahui; Lu, Xiumei; Wang, Bo; Liu, Xingyue

2018-01-01

Babinskaiidae is an extinct lacewing family of the superfamily Myrmeleontoidea. Hitherto, nine species of seven genera are described from the Lower and mid-Cretaceous. Here a new species of Babinskaiidae is described from Cretaceous Burmese amber, namely Parababinskaia makarkini sp. n. The new species possesses an A2 vein in the hind wing, suggesting that the loss of this vein might not be an autapomorphy of Babinskaiidae. The female of Electrobabinskaia burmana Lu, Zhang & Liu, 2017 is also described for the first time based on two specimens with their abdomens perfectly preserved, exhibiting a specialised sternum VI with paired elongate projections. A brief discussion of female genital characters is provided, which may increase our understanding of the morphology and phylogenetic position of Babinskaiidae.

PREFACE: Preface

NASA Astrophysics Data System (ADS)

Ye, Chaohui; Wang, Zhong Lin; Zhou, Bingkun

2011-02-01

The 3rd International Photonics and OptoElectronics Meeting (POEM 2010) was held from November 2-5, 2011, in Wuhan, China. POEM takes place annually, usually in November, with the aim of focusing on the key techniques of scientific frontiers and industry in the field of optoelectronics, understanding future trends as well as making the most of the industrial advantages of Wuhan - Optics Valley of China (OVC). POEM 2010 presented a plenary session and six parallel sessions. The latter comprised Laser Technology and Applications; Nano-enabled Energy Technologies and Materials; Optoelectronic Devices and Integration; Optoelectronic Sensing and Imaging; Solar Cells, Solid State Lighting and Information Display Technologies; and Tera-Hertz Science and Technology. 700 delegates from the field of optoelectronics - including world-famous experts, researchers, investors and entrepreneurs from more than 20 countries - attended the conference, among whom were 160 invited speakers. POEM 2010 once again received extensive praise for its intricate planning, rich contents, and the high-level and influential invited speakers which it attracted. Participants remarked that the presentations by the invited experts, the 'hot topic' discussions, students' posters, and the awards for papers were very engaging. They appreciated this valuable and beneficial opportunity for exchanging ideas with top photonics and optoelectronics experts. Our thanks are extended to the Conference Secretariat and Local Organizing Committee, who have been completely dedicated to their work, and who made the conference such a great success. We are also grateful for the financial support from 111 Project (B07038), and for the help with organization and coordination from Wuhan National Laboratory for Optoelectronics and Huazhong University of Science and Technology. Proceedings of POEM 2010234 papers were selected out of the 343 manuscripts submitted. The organizers of POEM 2010 are grateful to all the authors whose papers are being published in this volume of the Journal of Physics: Conference Series. The proceedings are divided into six sections according to different technical areas: Laser Technology and Applications (LTA) Nano-enabled Energy Technologies and Materials (NETM) Optoelectronic Devices and Integration (OEDI) Optoelectronic Sensing and Imaging (OSI) Solar Cells, Solid State Lighting and Information Display Technologies (SSID) Tera-Hertz Science and Technology (THST) Wuhan, PR ChinaDecember, 2010 Chaohui YeZhong Lin WangBingkun ZhouConference Chairs The 3rd International Photonics and OptoElectronics Meeting (POEM 2010)November 2-5, 2010Wuhan, China Supporters:Ministry of Education of China (MOE)State Administration of Foreign Experts Affairs (SAFEA)National Natural Science Foundation of China (NSFC) Sponsors:Huazhong University of Science and Technology (HUST)China Hubei Provincial Science Technology Department (HBSTD)Wuhan East Lake National Innovation Model Park Co-operating Societies:Institute of Physics (IOP)American Institute of Physics (AIP)International Biomedical Optics Society (IBOS)Laser Institute of America (LIA)Optical Society of America (OSA)IEEE Photonics Society (Singapore and Hongkong Chapters)Chinese Optical Society (COS) Organizer:Wuhan National Laboratory for Optoelectronics (WNLO) 1. LASER TECHNOLOGY AND APPLICATIONS (LTA)Editors:Peixiang Lu, Wuhan National Laboratory for Optoelectronics (China)Katsumi Midorikawa, Extreme Photonics Research Group, RIKEN (Japan)Bernd Wilhelmi, Jenoptik AG, Jena (Germany) 2. NANO-ENABLED ENERGY TECHNOLOGIES AND MATERIALS (NETM)Editors:Zhong Lin Wang, Wuhan National Laboratory for Optoelectronics (China) and Georgia Institute of Technology (USA)Guozhen Shen, Wuhan National Laboratory for Optoelectronics (China) 3. OPTOELECTRONIC DEVICES AND INTEGRATION (OEDI)Editors:Chinlon Lin, Bell Laboratory (USA)Jesper Moerk, Technical University of Denmark (Denmark)Xun Li, McMaster University (Canada)Xinliang Zhang, Wuhan National Laboratory for Optoelectronics (China)Junqiang Sun, Wuhan National Laboratory for Optoelectronics (China) 4. OPTOELECTRONIC SENSING AND IMAGING (OSI)Editors:Kecheng Yang, Wuhan National Laboratory for Optoelectronics (China)Pengcheng Li, Wuhan National Laboratory for Optoelectronics (China) 5. SOLAR CELLS, SOLID-STATE LIGHTING AND INFORMATION DISPLAY TECHNOLOGIES (SSID)Editors:Hiroshi Amano, Meijo University (Japan)Yibing Cheng, Monash University (Australia)Jinzhong Yu, Institute of Semiconductor, CAS (China)Changqing Chen, Wuhan National Laboratory for Optoelectronics (China)Hongwei Han, Wuhan National Laboratory for Optoelectronics (China)Guoli Tu, Wuhan National Laboratory for Optoelectronics (China) 6. TERA-HERTZ SCIENCE AND TECHNOLOGY (THST)Editors:Jianquan Yao, Tianjin University (China)Shenggang Liu, University of Electronic Science and Technology of China (China)X C Zhang, Rensselaer Polytechnic Institute (USA)Jinsong Liu, Wuhan National Laboratory for Optoelectronics (China) International Advisory Committee:Yibing Cheng, Monash University (Australia)Stephen Z D Cheng, University of Akron (USA)Min Gu, Swinburne University of Technology (Australia)Andrew B Holmes, the University of Melbourne (Australia)Chinlon Lin, Bell Laboratory (retired, USA)Xun Li, McMaster University (Canada)Shenggang Liu, University of Electronic Science and Technology of China (China)Jesper Moerk, Technical University of Denmark (Denmark)Dennis L Matthews, University of California, Davis (USA)Jiacong Shen, Jilin University (China)Ping Shum, Nanyang Technological University (Singapore)Chester C T Shu, Chinese University of Hong Kong (China)Valery V Tuchin, Saratov State University (Russia)Bruce Tromberg, University of California/Irvine (USA)Peiheng Wu, University of Nanjing (China)Alan Willner, University of Southern California (USA)Lihong Wang, Washington University in St. Louis (USA)C P Wong, Georgia Institute of Technology (USA)Jianquan Yao, Tianjin University (China)Xi Zhang, Tsinghua University (China)X C Zhang, Rensselaer Polytechnic Institute (USA) Program Committee:Qingming Luo, Wuhan National Laboratory for Optoelectronics (China) - ChairHiroshi Amano, Meijo University (Japan)Yibing Cheng, Monash University (Australia)Peixiang Lu, Wuhan National Laboratory for Optoelectronics (China)Ruxin Li, Shanghai Institute of Optics and Fine Mechanics (China)Chinlon Lin, Bell Laboratory (USA)Xun Li, McMaster University (Canada)Shenggang Liu, University of Electronic Science and Technology of China (China)Katsumi Midorikawa, Extreme Photonics Research Group, RIKEN (Japan)Jesper Moerk, Technical University of Denmark (Denmark)Valery V Tuchin, Saratov State University (Russia)Lihong Wang, Washington University in St. Louis (USA)Zhong Lin Wang, Georgia Institute of Technology(USA)Jinzhong Yu, Institute of Semiconductor, CAS (China)Jianquan Yao, Tianjin University (China)X C Zhang, Rensselaer Polytechnic Institute (USA) Local Organizing committee:Lin Lin, Wuhan National Laboratory for Optoelectronics (China) - ChairSheng Lu, Administration Committee of Wuhan East Lake Hi-tech Development Zone (China) - ChairChangqing Chen, Wuhan National Laboratory for Optoelectronics (China)Ling Fu, Wuhan National Laboratory for Optoelectronics (China)Hongwei Han, Wuhan National Laboratory for Optoelectronics (China)Peixiang Lu, Wuhan National Laboratory for Optoelectronics (China)Pengcheng Li, Wuhan National Laboratory for Optoelectronics (China)Jinsong Liu, Wuhan National Laboratory for Optoelectronics (China)Junqiang Sun, Wuhan National Laboratory for Optoelectronics (China)Guozhen Shen, Wuhan National Laboratory for Optoelectronics (China)Guoli Tu, Wuhan National Laboratory for Optoelectronics (China)Kecheng Yang, Wuhan National Laboratory for Optoelectronics (China)Xinliang Zhang, Wuhan National Laboratory for Optoelectronics (China)Yuandi Zhao, Wuhan National Laboratory for Optoelectronics (China) Local Secretariat:Xiaochun Xiao, Huazhong University of Science and Technology (China)Weiwei Dong, Huazhong University of Science and Technology (China)

Corresponding state-based correlations for the temperature-dependent surface tension of saturated hydrocarbons

NASA Astrophysics Data System (ADS)

Tian, Jianxiang; Zhang, Cuihua; Zhang, Laibin; Zheng, Mengmeng; Liu, Shuzhen

2017-10-01

Based on the recent progresses on the corresponding state-based correlations for the temperature-dependent surface tension of saturated fluids [I. Cachadiña, A. Mulero and J. X. Tian, Fluid Phase Equilibr. 442 (2017) 68; J. X. Tian, M. M. Zheng, H. L. Yi, L. B. Zhang and S. Z. Liu, Mod. Phys. Lett. B 31 (2017) 1750110], we proposed a new correlation for saturated hydrocarbons. This correlation includes three fluid-independent parameters and inquires the critical temperature, the triple-point temperature and the surface tension at the triple-point temperature as inputs for each hydrocarbon. Results show that this correlation can reproduce NIST data with absolute average deviation (AAD) less than 1% for 10 out of 19 hydrocarbons and AAD less than 5% for 17 out of 19 hydrocarbons, clearly better than other correlations.

Taxonomic notes on Babinskaiidae from the Cretaceous Burmese amber, with the description of a new species (Insecta, Neuroptera)

PubMed Central

Hu, Jiahui; Lu, Xiumei; Wang, Bo; Liu, Xingyue

2018-01-01

Abstract Babinskaiidae is an extinct lacewing family of the superfamily Myrmeleontoidea. Hitherto, nine species of seven genera are described from the Lower and mid-Cretaceous. Here a new species of Babinskaiidae is described from Cretaceous Burmese amber, namely Parababinskaia makarkini sp. n. The new species possesses an A2 vein in the hind wing, suggesting that the loss of this vein might not be an autapomorphy of Babinskaiidae. The female of Electrobabinskaia burmana Lu, Zhang & Liu, 2017 is also described for the first time based on two specimens with their abdomens perfectly preserved, exhibiting a specialised sternum VI with paired elongate projections. A brief discussion of female genital characters is provided, which may increase our understanding of the morphology and phylogenetic position of Babinskaiidae. PMID:29674912

FBXL5 interacts with p150 {sup Glued} and regulates its ubiquitination

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang Ning; Liu Jing; Ding Xia

2007-07-20

The microtubule motor cytoplasmic dynein and its activator dynactin drive vesicular transport and mitotic spindle organization. p150 {sup Glued} is the dynactin subunit responsible for binding to dynein and microtubules. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which governs phosphorylation-dependent ubiquitination and subsequent proteolysis. Our recent study showed that the proteolysis of mitotic kinesin CENP-E is mediated by SCF via a direct Skp1 link [D. Liu, N. Zhang, J. Du, X. Cai, M. Zhu, C. Jin, Z. Dou, C. Feng, Y. Yang, L. Liu, K. Takeyasu, W. Xie, X. Yao,more » Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis, Biochem. Biophys. Res. Commun. 345 (2006) 394-402]. Here we show that F-box protein FBXL5 interacts with p150 {sup Glued} and orchestrates its turnover via ubiquitination. FBXL5 binds to p150 {sup Glued} in vitro and in vivo. FBXL5 and p150 {sup Glued} co-localize primarily in the cytoplasm with peri-nuclear enrichment in HeLa cells. Overexpression of FBXL5 promotes poly-ubiquitination of p150 {sup Glued} and protein turnover of p150 {sup Glued} . Our findings provide a potential mechanism by which p150 {sup Glued} protein function is regulated by SCFs.« less

Integrated analysis of multiomic data reveals the role of the antioxidant network in the quality of sea buckthorn berry.

PubMed

He, Caiyun; Zhang, Guoyun; Zhang, Jianguo; Zeng, Yanfei; Liu, Juanjuan

2017-05-01

Berries of sea buckthorn, known as the "king of vitamin C," are abundant in antioxidants, have attractive colors, and are an excellent material with which to study the relationships between berry color, antioxidants, and berry quality. No study has yet determined the molecular basis of the relationship between sea buckhorn berries and their color and antioxidant levels. By using RNA-seq, LC-MS/MS, and LC/GC-MS technology and selecting red (darkest colored) and yellow (lightest colored) sea buckthorn berries at different development stages, this study showed that the red and yellow berry resulted from a higher ratio of lycopene to β-carotene and of β-carotene to lycopene content, respectively. The uronic acid pathway-a known animal pathway-in ascorbic acid synthesis was found in sea buckthorn berries, and the higher expression of UDP-glucuronosyltransferase in red berries was consistent with the higher content of ascorbic acid. In summary, multiomic data showed that the color of sea buckthorn berries is mainly determined by β-carotene and lycopene; red sea buckthorn berries were richer than yellow berries in antioxidants, such as carotenoids, flavonoids, and ascorbic acid; and the animal pathway might be operating in sea buckthorn.-He, C., Zhang, G., Zhang, J., Zeng, Y., Liu, J. Integrated analysis of multiomic data reveals the role of the antioxidant network in the quality of sea buckthorn berry. © FASEB.

Path integral molecular dynamics for exact quantum statistics of multi-electronic-state systems.

PubMed

Liu, Xinzijian; Liu, Jian

2018-03-14

An exact approach to compute physical properties for general multi-electronic-state (MES) systems in thermal equilibrium is presented. The approach is extended from our recent progress on path integral molecular dynamics (PIMD), Liu et al. [J. Chem. Phys. 145, 024103 (2016)] and Zhang et al. [J. Chem. Phys. 147, 034109 (2017)], for quantum statistical mechanics when a single potential energy surface is involved. We first define an effective potential function that is numerically favorable for MES-PIMD and then derive corresponding estimators in MES-PIMD for evaluating various physical properties. Its application to several representative one-dimensional and multi-dimensional models demonstrates that MES-PIMD in principle offers a practical tool in either of the diabatic and adiabatic representations for studying exact quantum statistics of complex/large MES systems when the Born-Oppenheimer approximation, Condon approximation, and harmonic bath approximation are broken.

Path integral molecular dynamics for exact quantum statistics of multi-electronic-state systems

NASA Astrophysics Data System (ADS)

Liu, Xinzijian; Liu, Jian

2018-03-01

An exact approach to compute physical properties for general multi-electronic-state (MES) systems in thermal equilibrium is presented. The approach is extended from our recent progress on path integral molecular dynamics (PIMD), Liu et al. [J. Chem. Phys. 145, 024103 (2016)] and Zhang et al. [J. Chem. Phys. 147, 034109 (2017)], for quantum statistical mechanics when a single potential energy surface is involved. We first define an effective potential function that is numerically favorable for MES-PIMD and then derive corresponding estimators in MES-PIMD for evaluating various physical properties. Its application to several representative one-dimensional and multi-dimensional models demonstrates that MES-PIMD in principle offers a practical tool in either of the diabatic and adiabatic representations for studying exact quantum statistics of complex/large MES systems when the Born-Oppenheimer approximation, Condon approximation, and harmonic bath approximation are broken.

Allied fractal - Signal 731-40 engines to HE. Mr. Dr-HC Jakob OETAMA''

NASA Astrophysics Data System (ADS)

Maksoed, Wh-

2016-10-01

Firstly :*) Boeing 85% probability wind 4 Pax-ISA conditions NBAA for `highly efficient AlliedSignal 731-40 engines of SpX, herewith adopts Beeckman -D to Beechjet 400A usually used by HE. Mr. Prof. Dr-Ing B.J. HABIBIE by ``per se''. For ``Fractal signals & Space-time Cartoons'' planned to be presented April 17, 2016 in SouthFoyer Room , Salt Lake City- UTAH, the US ever retrieved M. Riebe, et al.: Deterministic Quantum Teleportation with Atoms'', NPG-2004. Further, for poetic `fractal Heart' in an coincidences are ``the hardest thing in the World to understand is the income TAX'' notion from Albert Einstein to ``TinTin'' through Gilles Holst & ``dimer Holstein'' as well as took a terms of reference of Liu & Zhang: Adiabatic Limits & Foliations'' to relates infinite Hund coupling to suji leafs of dracaena angustifolia courtesies of Willybrordus Surendra Rendra. Heartfelt Gratitudes to HE. Mr. Prof. Ir. HANDOJO.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Xinhua; Zhang, Da; Liu, Bob, E-mail: bliu7@mgh.harvard.edu

Purpose: The knowledge of longitudinal dose distribution provides the most direct view of the accumulated dose in computed tomography (CT) scanning. The purpose of this work was to perform a comprehensive study of dose distribution width and energy absorption with a wide range of subject sizes and beam irradiated lengths. Methods: Cumulative dose distribution along the z-axis was calculated based on the previously published CT dose equilibration data by Li, Zhang, and Liu [Med. Phys. 40, 031903 (10pp.) (2013)] and a mechanism for computing dose on axial lines by Li, Zhang, and Liu [Med. Phys. 39, 5347–5352 (2012)]. Full widthmore » at half maximum (FWHM), full width at tenth maximum (FWTM), the total energy (E) absorbed in a small cylinder of unit mass per centimeter square about the central or peripheral axis, and the energy (E{sub in}) absorbed inside irradiated length (L) were subsequently extracted from the dose distribution. Results: Extensive results of FWHM, FWTM, and E{sub in}/E were presented on the central and peripheral axes of infinitely long PMMA (diameters 6–50 cm) and water (diameters 6–55 cm) cylinders with L < 100 cm. FWHM was greater than the primary beam width only on the central axes of large phantoms and also with L ranging from a few centimeter to about 33 cm. FWTM generally increased with phantom diameter, and could be up to 32 cm longer than irradiated length, depending on L, phantom diameter and axis, but was insensitive to phantom material (PMMA or water). E{sub in}/E increased with L and asymptotically approached unity for large L. As phantom diameter increased, E{sub in}/E generally decreased, but asymptotically approached constant levels on the peripheral axes of large phantoms. A heuristic explanation of dose distribution width results was presented. Conclusions: This study enables the reader to gain a comprehensive view of dose distribution width and energy absorption and provides useful data for estimating doses to organs inside or beyond the irradiated region. The dose length product (DLP) presented by CT scanners is equal to neither E nor E{sub in}. Both E and E{sub in} can be evaluated using the equations and results presented in this paper and are robust with both constant and variable tube current scanning techniques.« less

Advanced Materials and Processing 2010

NASA Astrophysics Data System (ADS)

Zhang, Yunfeng; Su, Chun Wei; Xia, Hui; Xiao, Pengfei

2011-06-01

Strain sensors made from MWNT/polymer nanocomposites / Gang Yin, Ning Hu and Yuan Li -- Shear band evolution and nanostructure formation in titanium by cold rolling / Dengke Yang, Peter D. Hodgson and Cuie Wen -- Biodegradable Mg-Zr-Ca alloys for bone implant materials / Yuncang Li ... [et al.] -- Hydroxyapatite synthesized from nanosized calcium carbonate via hydrothermal method / Yu-Shiang Wu, Wen-Ku Chang and Min Jou -- Modeling of the magnetization process and orthogonal fluxgate sensitivity of ferromagnetic micro-wire arrays / Fan Jie ... [et al.] -- Fabrication of silicon oxide nanowires on Ni coated silicon substrate by simple heating process / Bo Peng and Kwon-Koo Cho -- Deposition of TiOxNy thin films with various nitrogen flow rate: growth behavior and structural properties / S.-J. Cho ... [et al.] -- Observation on photoluminescence evolution in 300 KeV self-ion implanted and annealed silicon / Yu Yang ... [et al.] -- Facile synthesis of lithium niobate from a novel precursor H[symbol] / Meinan Liu ... [et al.] -- Effects of the buffer layers on the adhesion and antimicrobial properties of the amorphous ZrAlNiCuSi films / Pai-Tsung Chiang ... [et al.] -- Fabrication of ZnO nanorods by electrochemical deposition process and its photovoltaic properties / Jin-Hwa Kim ... [et al.] -- Cryogenic resistivities of NbTiAlVTaLax, CoCrFeNiCu and CoCrFeNiAl high entropy alloys / Xiao Yang and Yong Zhang -- Modeling of centrifugal force field and the effect on filling and solidification in centrifugal casting / Wenbin Sheng, Chunxue Ma and Wanli Gu -- Electrochemical properties of TiO[symbol] nanotube arrays film prepared by anodic oxidation / Young-Jin Choi ... [et al.] -- Effect of Ce additions on high temperature properties of Mg-5Sn-3Al-1Zn alloy / Byoung Soo Kang ... [et al.] -- Sono-electroless plating of Ni-Mo-P film / Atsushi Chiba, Masato Kanou and Wen-Chang Wu -- Diameter dependence of giant magneto-impedance effect in co-based melt extracted amorphous wires / Shuling Zhang, Dawei Xing and Jianfei Sun -- Effect of Yb addition on the microstructure and tensile properties of Mg-5Al alloy / Su Mi Jo ... [et al.] -- Finite element analysis of the warm deep-drawing process of magnesium matrix composite reinforced with CNTs / Li Weixue and Zhang Hujun -- Effect of ultrasonic shot peening on the microstructural evolution and mechanical properties of SUS304 / Deokgi Ahn ... [et al.] -- Microstructure of Fe-Cr surface infiltrated composite layer on gray iron substrate / Gui-Rong Yang ... [et al.] -- Effect of carbon contents and Ti addition on the microstructure of ultra-low carbon steel / Yinsheng He ... [et al.].Microstructure and mechanical property of laser direct manufacturing metal thin wall cylinder / X. D. Zhang ... [et al.] -- Evolution of morphology and composition of the carbides in Cr-Mo-V steel after service exposure / Jiling Dong ... [et al.] -- Thermal annealing treatment to achieve switchable and reversible wettability on ZnO nanowires surface / Changsong Liu ... [et al.] -- Physical and electrochemical properties of nanostructured nickel sulfide as a cathode material for lithium ion batteries / Seong-Ju Sim ... [et al.] -- Effect of heat treatment on fatigue behavior of biomedical Ni-Ti alloy wires under ultrasonic conditions / Zhou Huimin ... [et al.] -- The electrochemical behavior of Mg-Ce-Zn system / Kyung Chul Park ... [et al.] -- Fabrication of highly-oleophobic and superhydrophobic surfaces on microtextured Al substrates / Changsong Liu ... [et al.] -- Effect of cooling rate on microstructure and properties of Fe3Al intermetallics / Li Ya-Min, Liu Hong-Jun and Hao Yuan -- Calculation of laser transformation hardening with a circle beam / Binggong Yan and Jichang Liu -- The application of the unified homogeneous periodical boundary conditions to the prediction of effective elastic stiffness in a widespread field / Dong Yu, Hong Yang and Dong-Mei Luo -- Cyclic visco-plastic behavior of API X80 line-pipe steel and its finite element simulation / Kyong-Ho Chang and Gab-Chul Jang -- Residual stress distribution of 600MPa grade high tensile strength steel pipe using welding FE simulation / Kyong-Ho Chang and Gab-Chul Jang -- In-situ preparation and magnetic properties of Fe[symbol]O[symbol]/wood composite / Honglin Gao ... [et al.] -- The application of the cohesive zone model on the analysis of mechanical properties of carbon nano-tube composites with debonding interface / Wen-Liang Zhu and Dong-Mei Luo -- Microstructures and mechanical properties of As-Cast Mg-Zr-Ca alloys for biomedical applications / Ying-Long Zhou ... [et al.] -- Effect of polyurethane/nano-SiO[symbol] composites coating on thermo-mechanical properties of polyethylene film / Ching Yern Chee and Iskandar Idris Yaacob -- Effects evaluation for different rare earth elements in magnesium-lithium alloy / Bin Jiang ... [et al.] -- Effect of sintering temperature on the structure and bioactivity of HAp-5.0wt.%SO[symbol] bioceramic composites / Xiao-Wu Li ... [et al.] -- Study on the high cycle fatigue property of Ti-600 alloy at ambient temperature / Liying Zeng ... [et al.] -- Study on deformation-induced ferrite transformation of steel 2.25Cr1MoNb / Li Qing-Fen, Zhou Hui-Min and Chen Hong-Bin -- Effect of Fe addition on the cycle performance of FeS2 cathode for Li/FeS[symbol] battery / Young-Jin Choi ... [et al.] -- Effect of annealing process on recrystallization microstructure and texture of low carbon steel strip / Haiyan Wang ... [et al.].Grain-boundary segregation and co-segregation behavior of three elements in steel 2.25Gr1Mo / Wang Jun ... [et al.] -- Effect of partial crystallization on the mechanical properties of [symbol] bulk metallic glass / P. H. Tsai ... [et al.] -- Influence of plastic deformation on the evolution of defect structures, microhardness and electrical conductivity of copper / Jingmei Tao ... [et al.] -- Microstructure and room temperature mechanical properties of the Ni[symbol]Si-based alloy with titanium addition / S. K. Wang ... [et al.] -- Improvement of magnetic properties and size of directly casted Nd-Fe-B bulk magnets by Ti/Zr cosubstitutions / H. W. Chang ... [et al.] -- Wear behavior of the ceramic coatings on the Al6061 alloy prepared by plasma electrolytic oxidation / Jin Long Bian ... [et al.] -- Hydrogels with rapid thermal-responsibility by using liquid crystallite as template / Qingsong Zhang ... [et al.] -- The effects of TiO[symbol] buffer layer in carbon nanotubes growth on Ti substrate by thermal chemical vapor deposition and their electrochemical properties / Yong-Hwan Gwon ... [et al.] -- Phase transfer catalytic synthesis of 4-Benzyloxyl-3-Methoxylbenzaldehyde-Copolystyrene resin / Qiang Huang and Baozhong Zheng -- Compressive behaviour of nanocrystallilne Mg-5%Al alloys / H. Diao ... [et al.] -- Predicting the formation enthalpies of Al-Ga-In, Al-Ga-Sn, Cd-Ga-Sn and Ga-Sn-Zn liquid alloys by molecular interaction volume model / Hongwei Yang, Dongping Tao and Qingmei Yuan -- Low-temperature preparation and properties of high activity anatase TiO[symbol] aqueous sols / Qingju Liu ... [et al.] -- Effects of Ge mole fraction on electrical characteristics of strained SiGe channel p-MOSFET / Zhou Yang ... [et al.] -- Evaluation of oxidation and mechanical properties of the nano-sized WC-10%Nicrobraz composites consolidated by high frequency induction heated sintering / Duck-Soo Kang ... [et al.] -- Effect of ECAP on the high-temperature compressive deformation behavior of LY12 aluminum alloys / Qing-Wei Jiang ... [et al.] -- Surface energy effect on polymers adhesive bonding at room temperature / Yingxia Jin ... [et al.] -- Annealing effects on selfassembled Ge/Si (100) islands prepared by ion beam sputtering / Jie Yang ... [et al.] -- Effect of Gd on the microstructures and corrosion behaviors of magnesium alloy Mg-8.0Al-1.0Zn / Li Lei, Xie Shuisheng and Huang Guojie -- Synthesis, characterization and sensing properties of Perovskite EuFe[symbol] materials / Huen Kan ... [et al.] -- Synthesis and characterization of Ni(OH)[symbol] nanosheets by a simple route at low temperature / Qian Li ... [et al.] -- The prediction of laser clad parameters based on neural network / Jichang Liu and Libin Ni -- The effects of Y[symbol] doping on the phase structure and photoluminescence properties of (Gd[symbol]) red phosphors / Qi Zhu ... [et al.] -- Design of an in situ detection system for laser hardened width / Caixia Yang and Jichang Liu -- Numerical simulation microstructure morphology evolution and solute microsegregation of Al-Si-Cu ternary alloys during solidification process / Shuisheng Xie ... [et al.].A shear-lag model for carbon nonotube-reinforced magnesium matrix composites / Wei-Xue Li ... [et al.] -- Corrosion behavior of the Alumina Coated Al6061 Alloy by Plasma electrolytic oxidation / Kai Wang ... [et al.] -- A simple route for synthesis of tin dioxide nanorods based on improved solid-state reactions / Yuehua Li ... [et al.] -- Comparative study on microstructure and magnetic properties of amorphous wires with different diameters / Jing-Shun Liu ... [et al.] -- Chemical-Vapor-Depositing (CVD) aluminium film on steel surface with the disproportionation reaction of Al[symbol]S / Wu Guoyuan and Dai Yongnian -- The microstructure and properties of super martensitic stainless steel microalloyed with tungsten and copper / Dong Ye ... [et al.] -- Design of low elastic modulus Ti-Nb-Zr alloys for implant materials / Xiping Song ... [et al.] -- In situ monitoring molten pool parameters for detecting visible defects in laser cladding / Liusha Yang ... [et al.].

Linking Tengchong Terrane in SW Yunnan with Lhasa Terrane in southern Tibet through magmatic correlation

NASA Astrophysics Data System (ADS)

Xie, Jincheng; Zhu, Dicheng; Dong, Guochen; Zhao, Zhidan; Wang, Qing

2016-04-01

New zircon U-Pb data, along with the data reported in the literature, reveal five phases of magmatic activity in the Tengchong Terrane since the Early Paleozoic with spatial and temporal variations summarized as: Cambrian-Ordovician (500-460 Ma) to the eastern, minor Triassic (245-206 Ma) in the eastern and western, abundant Early Cretaceous (131-114 Ma) in the eastern, extensive Late Cretaceous (77-65 Ma) in the central, and Paleocene-Eocene (65-49 Ma) in the central and western Tengchong Terrane, in which the Cretaceous-Eocene magmatism was migrated from east to west (Xu et al., 2012). The increased zircon eHf(t) of the Early Cretaceous granitoids from -12.3 to -1.4 at ca. 131-122 Ma to -4.6 to +7.1 at ca. 122-114 Ma identified for the first time in this study and the magmatic flare-up at ca. 53 Ma in the central and western Tengchong Terrane (Wang et al., 2014, Ma et al., 2015) indicate the increased contributions from mantle- or juvenile crust-derived components. The spatial and temporal variations and changing magmatic compositions with time in the Tengchong Terrane closely resemble the Lhasa Terrane in southern Tibet. Such similarities, together with the data of stratigraphy and paleobiogeography (Zhang et al., 2013), enable us to propose that the Tengchong Terrane in SW Yunnan is most likely linked with the Lhasa Terrane in southern Tibet, both of which experience similar tectonomagmatic histories since the Early Paleozoic. References Ma, L.Y., Wang, Y.J., Fan, W.M., Geng, H.Y., Cai, Y.F., Zhong, H., Liu, H.C., Xing, X.W., 2014. Petrogenesis of the early Eocene I-type granites in west Yingjiang (SW Yunnan) and its implication for the eastern extension of the Gangdese batholiths. Gondwana Research 25, 401-419. Wang, Y.J., Zhang, L.M., Cawood, P.A., Ma, L.Y., Fan, W.M., Zhang, A.M., Zhang, Y.Z., Bi, X.W., 2014. Eocene supra-subduction zone mafic magmatism in the Sibumasu Block of SW Yunnan: Implications for Neotethyan subduction and India-Asia collision. Lithos 206-207, 384-399. Xu, Y.G., Yang, Q.J., Lan, J.B., Luo, Z.Y., Huang, X.L., Shi, Y.R., Xie, L.W., 2012. Temporal-spatial distribution and tectonic implications of the batholiths in the Gaoligong-Tengliang-Yingjiang area, western Yunnan: Constraints from zircon U-Pb ages and Hf isotopes. Journal of Asian Earth Sciences 53, 151-175. Zhang, Y.C., Shi, G.R., Shen, S.Z., 2013. A review of Permian stratigraphy, paleobiogeography and palaeogeography of the Qinghai-Tibet Plateau. Gondwana Research 24, 55-76.

Soft X-ray Spectromicroscopy of Polymers

NASA Astrophysics Data System (ADS)

Ade, Harald

1997-03-01

The development of Near Edge X-ray Absorption Fine Structure (NEXAFS) microscopy^1 and linear dichroism microscopy^2 over the last few years utilizing the X1-Scanning Transmission X-ray Microscope (X1-STXM) at the National Synchrotron Light Source provides excellent specificity to various functional groups and moieties in organic molecules and polymeric materials at a spatial resolution of 50 nm. This chemical specificity can be utilized to map the distribution of various compounds in a material, or to micro-chemically analyze small sample areas. Examples of applications include the study of various phase-separated polymers (polyurethanes, liquid crystalline polyesters), multicomponent polymer blends, polymer laminates, and other organic materials such as coal^3. Linear dichroism microscopy furthermore explores the polarization dependence of NEXAFS in (partially) oriented materials, and can determine the orientation of specific functional groups. Applications of linear dichroism microscopy have focused so far on determining the relative degree of radial orientation in Kevlar fibers^3. ^1 H. Ade, X. Zhang, S. Cameron, C. Costello, J. Kirz, and S. Williams, Science 258, 972 (1992). ^2 H. Ade and B. Hsiao, Science 262, 1427 (1993). ^3 Acknowledgement: My callaborators are B. Hsiao, S. Subramoney, B. Wood, I. Plotzker, E. Rightor, G. Mitchell, C. Sloop, D.-J. Liu, S.-C. Liu, J. Marti, C. Zimba, A. P. Smith, R. Spontak, R. Fornes, R. Gilbert, C. Cody, A. Hitchcock and S. Urquhart. The X1-STXM is built and maintained by J. Kirz and C. Jacobsen and their groups. Work supported by: NSF Young Investigator Award (DMR-9458060), DuPont Young Professor Grant, and Dow Chemical.

Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue-kidney crosstalk.

PubMed

Liu, Xue-Jing; Wu, Xiao-Yue; Wang, Huan; Wang, Su-Xia; Kong, Wei; Zhang, Ling; Liu, George; Huang, Wei

2018-05-08

Seipin deficiency is responsible for type 2 congenital generalized lipodystrophy with severe loss of adipose tissue (AT) and could lead to renal failure in humans. However, the effect of Seipin on renal function is poorly understood. Here we report that Seipin knockout (SKO) mice exhibited impaired renal function, enlarged glomerular and mesangial surface areas, renal depositions of lipid, and advanced glycation end products. Elevated glycosuria and increased electrolyte excretion were also detected. Relative renal gene expression in fatty acid oxidation and reabsorption pathways were impaired in SKO mice. Elevated glycosuria might be associated with reduced renal glucose transporter 2 levels. To improve renal function, AT transplantation or leptin administration alone was performed. Both treatments effectively ameliorated renal injury by improving all of the parameters that were measured in the kidney. The treatments also rescued insulin resistance and low plasma leptin levels in SKO mice. Our findings demonstrate for the first time that Seipin deficiency induces renal injury, which is closely related to glucolipotoxicity and impaired renal reabsorption in SKO mice, and is primarily caused by the loss of AT and especially the lack of leptin. AT transplantation and leptin administration are two effective treatments for renal injury in Seipin-deficient mice.-Liu, X.-J., Wu, X.-Y., Wang, H., Wang, S.-X., Kong, W., Zhang, L., Liu, G., Huang, W. Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue-kidney crosstalk.

Nonperiodic metallic gratings transparent for broadband terahertz waves

NASA Astrophysics Data System (ADS)

Fan, Ren-Hao; Ren, Xiao-Ping; Peng, Ru-Wen; Huang, Xian-Rong; Wang, Mu

Recently, we demonstrate both theoretically and experimentally that nonperiodic metallic gratings can become transparent for broadband terahertz waves. Quasiperiodic and disordered metallic gratings effectively weaken and even eliminate Wood's anomalies, which are the diffraction-related characters of periodic gratings. Consequently, both the transparence bandwidth and transmission efficiency are significantly increased due to the structural aperiodicity. Furthermore, we show that for a specific light source, for example, a line source, a corresponding nonperiodic transparent grating can be also designed. We expect that our findings can be applied for transparent conducting panels, perfect white-beam polarizers, antireflective conducting solar cells, and beyond. References: X. P. Ren, R. H. Fan, R. W. Peng, X. R. Huang, D. H. Xu, Y. Zhou, and Mu Wang, Physical Review B, 91, 045111 (2015); R. H. Fan, R. W. Peng, X. R. Huang, J. Li, Y. Liu, Q. Hu, Mu. Wang, and X. Zhang, Advanced Materials, 24, 1980 (2012); and X. R. Huang, R. W. Peng, and R. H. Fan. Physical Review Letters, 105, 243901 (2010).

Monodomain dynamics for rigid rod and platelet suspensions in strongly coupled coplanar linear flow and magnetic fields. II. Kinetic theory

NASA Astrophysics Data System (ADS)

Forest, M. Gregory; Sircar, Sarthok; Wang, Qi; Zhou, Ruhai

2006-10-01

We establish reciprocity relations of the Doi-Hess kinetic theory for rigid rod macromolecular suspensions governed by the strong coupling among an excluded volume potential, linear flow, and a magnetic field. The relation provides a reduction of the flow and field driven Smoluchowski equation: from five parameters for coplanar linear flows and magnetic field, to two field parameters. The reduced model distinguishes flows with a rotational component, which map to simple shear (with rate parameter) subject to a transverse magnetic field (with strength parameter), and irrotational flows, for which the reduced model consists of a triaxial extensional flow (with two extensional rate parameters). We solve the Smoluchowski equation of the reduced model to explore: (i) the effect of introducing a coplanar magnetic field on each sheared monodomain attractor of the Doi-Hess kinetic theory and (ii) the coupling of coplanar extensional flow and magnetic fields. For (i), we show each sheared attractor (steady and unsteady, with peak axis in and out of the shearing plane, periodic and chaotic orbits) undergoes its own transition sequence versus magnetic field strength. Nonetheless, robust predictions emerge: out-of-plane degrees of freedom are arrested with increasing field strength, and a unique flow-aligning or tumbling/wagging limit cycle emerges above a threshold magnetic field strength or modified geometry parameter value. For (ii), irrotational flows coupled with a coplanar magnetic field yield only steady states. We characterize all (generically biaxial) equilibria in terms of an explicit Boltzmann distribution, providing a natural generalization of analytical results on pure nematic equilibria [P. Constantin, I. Kevrekidis, and E. S. Titi, Arch. Rat. Mech. Anal. 174, 365 (2004); P. Constantin, I. Kevrekidis, and E. S. Titi, Discrete and Continuous Dynamical Systems 11, 101 (2004); P. Constantin and J. Vukadinovic, Nonlinearity 18, 441 (2005); H. Liu, H. Zhang, and P. Zhang, Comm. Math. Sci. 3, 201 (2005); C. Luo, H. Zhang, and P. Zhang, Nonlinearity 18, 379 (2005); I. Fatkullin and V. Slastikov, Nonlinearity 18, 2565 (2005); H. Zhou, H. Wang, Q. Wang, and M. G. Forest, Nonlinearity 18, 2815 (2005)] and extensional flow-induced equilibria [Q. Wang, S. Sircar, and H. Zhou, Comm. Math. Sci. 4, 605 (2005)]. We predict large parameter regions of bi-stable equilibria; the lowest energy state always has principal axis aligned in the flow plane, while another minimum energy state often exists, with primary alignment transverse to the coplanar field.

Possible polyphase metamorphic evolution of high grade metabasic rocks from the Songshugou ophiolite, Qinling orogen, China

NASA Astrophysics Data System (ADS)

Belic, Maximilian; Hauzenberger, Christoph; Dong, Yunpeng; Chen, Danling

2014-05-01

The Proterozoic Songshugou ophiolite consists of a series of ultrabasic and tholeitic metabasic rocks. They were emplaced as a lense shaped body into the southern margin of the Qinling Group. Isotope composition and trace element geochemistry display an E-MORB and T-MORB signature for the mafic rocks (Dong et al., 2008). Within the ophiolite sequence some rudimental fresh peridotites (dunites and harzburgites) within serpentines display low CaO (<0.39 wt.%) and Al2O3 (<0.51 wt.%) as well as high MgO (41-48 wt.%) contents, which can be classified as depleted non-fertile mantle rocks. The metabasic rocks comprise the mineral assemblage garnet, amphibole, symplectitic pyroxenes, ilmenite, apatite, ±zoisite, ±sphene and show a strong retrograde metamorphic overprint. Garnet typically contains many inclusions within the core but are nearly inclusion free at the rim. The cores have sometimes snowball textures indicating initially syndeformative growth. Albite and prehnite were found in central parts of garnet. In the outer portions, pargasitic amphibole, rutile and a bluish amphibole, probably glaukophane were found. Garnet zoning pattern clearly show a discontinous growth seen in an sudden increase in grossular and decrease in almandine components. The symplectitic pyroxenes are of diopsidic composition which enclose typically prehnite and not albite, as common in retrograde eclogitic rocks. Different stages of garnet breakdown to plagioclase and amphibole, from thin plagioclase rims surrounding the garnets to plagioclase rich pseudomorphs, can be observed in different samples. Based on symplectitic pyroxenes a high pressure metamorphic event can be concluded (Zhang, 1999). The garnet breakdown to plagioclase and the symplectites clearly indicate a rapid exhumation phase. The age of the metamorphic event is probably related to the closure of the Shangdan ocean during the early Paleozoic. It is unclear if the garnet rims grew during a later stage of the metamorphic cycle or developed during a separate event. The financial support by Eurasia-Pacific Uninet is gratefully acknowledged. Dong, Y.P., Zhou, M.F., Zhang, G.W., Zhou, D.W., Liu, L., Zhang, Q., 2008. The Grenvillian Songshugou ophiolite in the Qinling Mountains, Central China: implications for the tectonic evolution of the Qinling orogenic belt. Journal of Asian Earth Science 32 (5-6), 325-335. Zhang, Z.J., 1999. Metamorphic evolution of garnet-clinopyroxene-amphibole rocks from the Proterozoic Songshugou mafic-ultramafic complex, Qinling Mountains, central China. The Island Arc, 8, 259-280.

Effects of climate change on deep-water oxygen and winter mixing in a deep lake (Lake Geneva)

NASA Astrophysics Data System (ADS)

Schwefel, Robert; Alfred, Wüest; Damien, Bouffard

2016-04-01

Oxygen is the most important dissolved gas for lake ecosystems. Because low oxygen concentrations are an ongoing problem in many parts of the oceans and numerous lakes, oxygen depletion processes have been intensively studied over the last decades and were mainly attributed to high nutrient loads. Recently, climate-induced changes in stratification and mixing behavior were recognized as additional thread to hypolimnetic oxygen budgets in lakes and reservoirs [Matzinger et al., 2007; Zhang et al., 2015]. Observational data of Lake Geneva, a deep perialpine lake situated between France and Switzerland showed no decreasing trend in hypoxia over the last 43 years, despite an impressive reduction in nutrient input during this period. Instead, hypoxic conditions were predominantly controlled by deep mixing end of winter and in turn by winter temperatures. To test the sensitivity of Lake Geneva on future climate change and changes in water transparency, we simulated the hydrodynamics and temperature of Lake Geneva under varying conditions for atmospheric temperature and water clarity performed with the one-dimensional model SIMSTRAT [Goudsmit, 2002]. The results show, that the stratification in lakes is only weakly affected by changes in light absorption due to varying water quality. For conditions expected for the end of the century, a decrease in the annual mean deep convective mixing of up to 45 m is predicted. Also complete mixing events over the whole lake are less likely to occur. A change in the hypolimnetic oxygen concentration of up to 20% can thus be expected in the future. These results show, that changes in deep mixing have an equally strong impact as eutrophication on the deep-water oxygen development of oligomictic lakes and have to be considered in the prediction of the future development of lakes. References: Goudsmit, G. H., H. Burchard, F. Peeters, and A. Wüest (2002), Application of k-ɛ turbulence models to enclosed basins: The role of internal seiches, J. Geophys. Res., 107(C12), 3230. Matzinger, A., M. Schmid, E. Veljanoska-Sarafiloska, S. Patceva, D. Guseska, B. Wagner, B. Müller, M. Sturm, and A. Wüest (2007), Eutrophication of ancient Lake Ohrid: Global warming amplifies detrimental effects of increased nutrient inputs, Limnol. Oceanogr., 52(1), 338-353. Zhang, Y., Z. Wu, M. Liu, J. He, K. Shi, Y. Zhou, M. Wang, and X. Liu (2015), Dissolved oxygen stratification and response to thermal structure and long-term climate change in a large and deep subtropical reservoir (Lake Qiandaohu, China), Water Res., 75, 249-258.

Energy transfer ultraviolet photodetector with 8-hydroxyquinoline derivative-metal complexes as acceptors

NASA Astrophysics Data System (ADS)

Wu, Shuang-Hong; Li, Wen-Lian; Chen, Zhi; Li, Shi-Bin; Wang, Xiao-Hui; Wei, Xiong-Bang

2015-02-01

We choose 8-hydroxyquinoline derivative-metal complexes (Beq, Mgq, and Znq) as the acceptors (A) and 4,4',4”-tri-(2-methylphenyl phenylamino) triphenylaine (m-MTDATA) as the donor (D) respectively to study the existing energy transfer process in the organic ultraviolet (UV) photodetector (PD), which has an important influence on the sensitivity of PDs. The energy transfer process from D to A without exciplex formation is discussed, differing from the working mechanism of previous PDs with Gaq [Zisheng Su, Wenlian Li, Bei Chu, Tianle Li, Jianzhuo Zhu, Guang Zhang, Fei Yan, Xiao Li, Yiren Chen and Chun-Sing Lee 2008 Appl. Phys. Lett. 93 103309)] and REq [J. B. Wang, W. L. Li, B. Chu, L. L. Chen, G. Zhang, Z. S. Su, Y. R. Chen, D. F. Yang, J. Z. Zhu, S. H. Wu, F. Yan, H. H. Liu, C. S. Lee 2010 Org. Electron. 11 1301] used as an A material. Under 365-nm UV irradiation with an intensity of 1.2 mW/cm2, the m-MTDATA:Beq blend device with a weight ratio of 1:1 shows a response of 192 mA/W with a detectivity of 6.5× 1011 Jones, which exceeds those of PDs based on Mgq (146 mA/W) and Znq (182 mA/W) due to better energy level alignment between m-MTDATA/Beq and lower radiative decay. More photophysics processes of the PDs involved are discussed in detail. Project supported by the National Natural Science Foundation of China (Grant Nos. 61371046, 61405026, 61474016, and 61421002) and China Postdoctoral Science Foundation (Grant No. 2014M552330).

Insight into CH4 dissociation on NiCu catalyst: A first-principles study

NASA Astrophysics Data System (ADS)

Liu, Hongyan; Zhang, Riguang; Yan, Ruixia; Li, Jingrui; Wang, Baojun; Xie, Kechang

2012-08-01

A density-functional theory method has been conducted to investigate the dissociation of CH4 on NiCu (1 1 1) surface. Two models: uniform surface slab model (Model A) and Cu-rich surface slab model (Model B) have been constructed to represent the NiCu (1 1 1) surface, in which the ratio of Ni/Cu is unit. The obtained results on the two models have been compared with those obtained on pure Ni (1 1 1) and Cu (1 1 1). It is found that the adsorption of CHx(x = 1-3) on Model B are weaker than on Model A. The rate-determining steps of CH4 dissociation on Model A and B both are the dissociation of CH, and the corresponding activation barriers are 1.37 and 1.63 eV, respectively. Obviously, it is approximately equal on Model A to that on pure Ni (1 1 1) [H. Liu, R. Zhang, R. Yan, B. Wang, K. Xie, Applied Surface Science 257 (2011) 8955], while it is lower by 0.58 eV on Model B compared to that on pure Cu (1 1 1). Therefore, the Cu-rich surface has better carbon-resistance ability than the uniform one. Those results well explain the experimental facts that NiCu/SiO2 has excellent catalytic performance and long-term stability [H.-W. Chen, C.-Y. Wang, C.-H. Yu, L.-T. Tseng, P.-H. Liao, Catalysis Today 97 (2004) 173], however, there is serious carbon deposition on NiCu/MgO-Al2O3 in CO2 reforming of methane [J. Zhang, H. Wang, A. K. Dalai, Journal of Catalysis 249 (2007) 300].

Rhythmic expression of miR-27b-3p targets the clock gene Bmal1 at the posttranscriptional level in the mouse liver.

PubMed

Zhang, Wenxiang; Wang, Peng; Chen, Siyu; Zhang, Zhao; Liang, Tingming; Liu, Chang

2016-06-01

Circadian clocks orchestrate daily oscillations in mammalian behaviors, physiology, and gene expression. MicroRNAs (miRNAs) play a crucial role in fine-tuning of the circadian system. However, little is known about the direct regulation of the clock genes by specific miRNAs. In this study, we found that miR-27b-3p exhibits rhythmic expression in the metabolic tissues of the mice subjected to constant darkness. MiR-27b-3p's expression is induced in livers of unfed and ob/ob mice. In addition, the oscillation phases of miR-27b-3p can be reversed by restricted feeding, suggesting a role of peripheral clock in regulating its rhythmicity. Bioinformatics analysis indicated that aryl hydrocarbon receptor nuclear translocator-like (also known as Bmal1) may be a direct target of miR-27b-3p. Luciferase reporter assay showed that miR-27b-3p suppressed Bmal1 3' UTR activity in a dose-dependent manner, and mutagenesis of their binding site abolished this suppression. Furthermore, overexpression of miR-27b-3p dose-dependently reduced the protein expression levels of BMAL1 and impaired the endogenous BMAL1 and gluconeogenic protein rhythmicity. Collectively, our results suggest that miR-27b-3p plays an important role in the posttranscriptional regulation of BMAL1 protein in the liver. MiR-27b-3p may serve as a novel node to integrate the circadian clock and energy metabolism.-Zhang, W., Wang, P., Chen, S., Zhang, Z., Liang, T., Liu, C. Rhythmic expression of miR-27b-3p targets the clock gene Bmal1 at the posttranscriptional level in the mouse liver. © FASEB.

The expression of the genes involved in leucine catabolism of Pseudomonas aeruginosa is controlled by the transcriptional regulator LiuR and by the CbrAB/Crc system.

PubMed

Díaz-Pérez, Alma Laura; Núñez, Cinthia; Meza Carmen, Victor; Campos-García, Jesús

2018-05-19

Pseudomonas aeruginosa metabolizes leucine through the leucine/isovalerate utilization pathway, whose enzymes are encoded in the liuRABCDE gene cluster (liu). In this study, we investigated the role of the LiuR protein in the liu cluster regulation. Our results indicated that liu expression is regulated at the transcriptional level by LiuR. Mobility shift assays using purified recombinant His-tagged LiuR showed that it was able to bind at the promoter region of liuR, in a dose-dependent manner. Results revealed that expression of the liu operon is subjected to carbon catabolite repression control (CCR); protein LiuD was strongly expressed in the presence of leucine, but it was repressed in the presence of glucose or succinate. Furthermore, this CCR control was dependent on LiuR as in the liuR - mutant the LiuD protein was strongly expressed in all the carbon sources tested. In agreement with this result, in the absence of the Crc protein, LiuD was expressed independently of the carbon source used, whereas in a cbrB - mutant its expression was severely impaired. The results indicated that the liu cluster is subjected to a coordinated transcriptional and translational regulation by the LiuR repressor and by the CbrAB/Crc system, respectively, in response to the available carbon source. Copyright © 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Potential of Gdgts as Temperature Proxies Along Altitudinal Transects in East Africa

NASA Astrophysics Data System (ADS)

Coffinet, Sarah; Huguet, Arnaud; Omuombo, Christine; Williamson, David; Fosse, Céline; Anquetil, Christine; Derenne, Sylvie

2014-05-01

Glycerol dialkyl glycerol tetraethers (GDGTs) are lipids of high molecular weight and include the isoprenoid GDGTs (iGDGTs) produced by Archaea and the branched GDGTs (brGDGTs) produced by unknown bacteria. Several indices were developed to describe the relationship between GDGT distribution and environmental parameters: the TEX86 (tetraether index of tetraethers consisting of 86 carbons), based on the relative abundances of iGDGTs in sediments, and the MBT (methylation index of branched tetraethers) and CBT (cyclisation ratio of branched tetraethers), based on the relative abundance of brGDGTs in soils. The TEX86 was shown to correlate well with water surface temperature, and the MBT and CBT with mean annual air temperature (MAAT) and soil pH. The GDGTs are increasingly used as temperature proxies. In this study, 41 surface soils were sampled along two altitudinal transects, from 500 to 2800 meters in Mount Rungwe (South western, Tanzania) and from 1897 to 3268 meters in Mount Kenya (Central Kenya). MAAT was reconstructed along the two transects using the MBT/CBT proxies. A linear correlation between the MBT/CBT-derived temperatures and the altitude (R2=0.83) was obtained by combining results of the two transects. The reconstructed temperature lapse rate (0.5 ° C/100 m) was consistent with the one determined from temperature measurements at six altitudes. These results show that the MBT/CBT is a suitable and robust temperature proxy in East Africa. In Mt. Rungwe soil samples, the TEX86 index, which was mainly used to reconstruct water surface temperatures until now, was found to vary linearly with altitude (R2=0.50). Such a relationship between TEX86 and altitude in organic soils has also been recently noticed in Mt. Xiangpi, China (Liu et al., 2013; R2=0.68). The adiabatic cooling of air with altitude could explain the TEX86 variation with altitude. If such a relationship is confirmed, the use of the TEX86 as a temperature proxy could be extended to soil environments. However, a lower correlation between TEX86 and altitude was observed for Mt. Kenya samples, implying that the environmental factors affecting the TEX86 values should be further investigated. Moreover, a given TEX86 value was shown to correspond to a much higher altitude (ca. 1800 m higher) for Mt. Xiangpi soils (Liu et al., 2013) than for Mt. Rungwe samples, suggesting that the geographical origin of the soils could also impact the TEX86 values. Therefore, a better understanding of the environmental mechanisms controlling the iGDGTs distribution in soils is needed prior any application of the TEX86 as a temperature proxy in these environments. REFERENCES Liu, W., Wang, H., Zhang, C.L., Liu, Z., He, Y., 2013. Organic Geochemistry 57, 76-83.

The study of the geomagnetic excursions and the relative intensities from Chinese loess 10Be over the past 130 ka

NASA Astrophysics Data System (ADS)

Zhou, W.; Xian, F.; Beck, J.; An, Z.; Wu, Z.; Liu, M.; Chen, M.; Priller, A.; Kutschera, W.; Jull, A. T.; Yu, H.; Song, S.; Cheng, P.; Kong, X.

2009-12-01

Chinese loess is well-known archive for the paleogeomagnetic and paleoclimatic studies [Zhou et al., 1990; An et al., 1990; Zhu et al., 2007]. However, earlier efforts to extract weak geomagnetic excursion signals from Chinese loess 10Be were always unsuccessful due to the complexities of loess 10Be, which results in the fact that loess 10Be was only used as a climatic proxy [Shen et al., 1992; Beer et al.,1993; Gu et al.,1996]. Meanwhile, knowledge on the precise stratigraphic horizons of geomagnetic excursions with a reliable dating [Channell, 2006], on whether the short-lived excursions such as Blake can not be recorded in paleosol unit are still controversial. Here, we present the reconstructed past 130ka geomagnetic excursions and relative paleointensities for the first time from 10Be records in two Chinese loess sections. Results are comparative with those of independent geomagnetic research on Atlantic and Pacific sediments. The derived Laschamp and Blake events lie in the loess-paleosol (L1SS1 and S1SS3) corresponding to mid MIS 3 and 5e respectively. Our studies prove the potential application of the complex loess 10Be for long-term geomagnetic tracing and provide new evidence to answer the long-existing debates on the precise stratigraphic horizon of geomagnetic excursions. Our study suggests the potential application of loess-paleosol 10Be for reconstructing geomagnetic intensity variations spanning the whole Quaternary. References 1. Zhou, L. P., F. Oldfield, A. G. Wintle, S. G. Robinson, and J. T. Wang (1990), Partly pedogenic origin of magnetic variations in Chinese loess, Nature, 346, 737-739. 2. An, Z. S., T. S. Liu, Y. C. Lu, S. C. Porter, G. Kukla, X. H. Wu, and Y. M. Hua (1990), The long-term paleomonsoon variation recorded by the loess-paleosol sequence in Central China, Quat. Int., 7-8, 91-95. 3. Zhu, R. X., R. Zhang, C. L. Deng, Y. X. Pan, Q. S. Liu, and Y. B. Sun (2007), Are Chinese loess deposits essentially continuous?, Geophys. Res. Lett., 34, L17306. 4. Shen, C. D., J. Beer, T. S. Liu, H. Oeschger, G. Bonani, M. Suter, and W.Wolfli (1992), 10Be in Chinese loess, Earth Planet. Sci. Lett., 109(1-2), 169-177. 5. Gu, Z. Y., D. Lal, T. S. Liu, J. Southon, M. W. Caffee, Z. T. Guo, and M. Y.Chen (1996), Five million year 10Be record in Chinese loess and red-clay: climate and weathering relationships, Earth Planet. Sci. Lett., 144(1-2), 273-287. 6. Beer, J., C. D. Shen, F. Heller ,T.S. Liu, G. Bonani, B. Dittrich, M. Suter, and P.W. Kubik (1993), 10Be and magnetic susceptibility in Chinese Loess, Geophys. Res. Lett., 20(1), 57-60 7. Channell, J. E. T.(2006), Late Brunhes polarity excursions (Mono Lake, Laschamp, Iceland Basin and Pringle Falls) recorded at ODP Site 919 (Irminger Basin), Earth Planet. Sci. Lett., 244(1-2), 378-393.

New species of Nipponoserica and Paraserica from China (Coleoptera, Scarabaeidae, Sericini).

PubMed

Liu, Wan-Gang; Fabrizi, Silvia; Yang, Xingke; Bai, Ming; Ahrens, Dirk

2017-01-01

The species of the genera Nipponoserica Nomura, 1973 and Paraserica Reitter, 1896 from China are revised. The following eight new species are described from China: Paraserica camillerii Ahrens, Fabrizi, & Liu, sp. n. , P. mupuensis Ahrens, Fabrizi, & Liu, sp. n. , P. wangi Ahrens, Fabrizi, & Liu, sp. n. , Nipponoserica alloshanghaiensis Ahrens, Fabrizi, & Liu, sp. n. , N. anjiensis Ahrens, Fabrizi, & Liu, sp. n. , N. jiankouensis Ahrens, Fabrizi, & Liu, sp. n. , N. henanensis Ahrens, Fabrizi, & Liu, sp. n. , and N. sericanioides Ahrens, Fabrizi, & Liu, sp. n. A key to the species of the genera examined here and maps of the species distribution are provided. Habitus and male genitalia are illustrated.

Seven new species of the Stenus cirrus group (Coleoptera, Staphylinidae) from Guangxi, South China.

PubMed

Liu, Sheng-Nan; Tang, Liang

2017-05-16

Seven new species of the Stenus cirrus group collected from Guangxi, South China are described and illustrated: S. hujiayaoi Liu and Tang, sp. n., S. bullatus Liu and Tang, sp. n., S. exesus Liu and Tang, sp. n., S. damingshanus Liu and Tang, sp. n., S. jinxiuensis Liu and Tang, sp. n., S. lianhuashanus Liu and Tang, sp. n., S. hechiensis Liu and Tang, sp. n. The diagnostic characters of the new species are illustrated, and a key to species of the group from Guangxi is provided.

New species of Nipponoserica and Paraserica from China (Coleoptera, Scarabaeidae, Sericini)

PubMed Central

Liu, Wan-Gang; Fabrizi, Silvia; Yang, Xingke; Bai, Ming; Ahrens, Dirk

2017-01-01

Abstract The species of the genera Nipponoserica Nomura, 1973 and Paraserica Reitter, 1896 from China are revised. The following eight new species are described from China: Paraserica camillerii Ahrens, Fabrizi, & Liu, sp. n., P. mupuensis Ahrens, Fabrizi, & Liu, sp. n., P. wangi Ahrens, Fabrizi, & Liu, sp. n., Nipponoserica alloshanghaiensis Ahrens, Fabrizi, & Liu, sp. n., N. anjiensis Ahrens, Fabrizi, & Liu, sp. n., N. jiankouensis Ahrens, Fabrizi, & Liu, sp. n., N. henanensis Ahrens, Fabrizi, & Liu, sp. n., and N. sericanioides Ahrens, Fabrizi, & Liu, sp. n. A key to the species of the genera examined here and maps of the species distribution are provided. Habitus and male genitalia are illustrated. PMID:29308025

New taxa of Meconematini (Orthoptera: Tettigoniidae: Meconematinae) from Guangxi, China.

PubMed

Wang, Hanqiang; Liu, Xianwei; Li, Kai

2015-04-02

The following new taxa of Meconematini from Guangxi province were described: Sinothaumaspis damingshanicus Wang, Liu, Li gen. & sp. nov., Aphlugiolopsis punctipennis Wang, Liu, Li gen. & sp. nov., Eoxizicus (Eoxizicus) curvicercus Wang, Liu, Li sp. nov., Meconemopsis paraquadrinotata Wang, Liu, Li sp. nov., Neocrytopsis? unicolor Wang, Liu, Li sp. nov., Xiphidiopsis (Dinoxiphidiopsis) expressa Wang, Liu, Li sp. nov. Xiphidiopsis (Xiphidiopsis) fischerwaldheimi Gorochov, 1993, a synonym of Xiphidiopsis (Xiphidiopsis) jinxiuensis Xia & Liu, 1990 was described. The opposite gender of Sinocyrtaspis truncate Liu, 2000 and Abaxinicephora excellens Gorochov & Kang, 2005 were firstly described.  Xiphidiopsis (Dinoxiphidiopsis) jacobsoni Gorochov, 1993 was also firstly recorded from China. Two new combinations,  Meconemopsis quadrinotata (Bey-Bienko, 1971) Wang, Liu, Li comb. nov. and Xiphidiopsis (Dinoxiphidiopsis) fanjingshanensis (Shi & Du, 2006) Wang, Liu, Li comb. nov., as well as a synonym of the former Xizicus (Axizicus) xizangensis Jiao & Shi 2013 syn. nov. which respectively relate to M. paraquadrinotata sp. nov. and X. (D.) expressa sp. nov., were also noted.

Taxonomic review on the subgenus Tripodura Townes (Diptera: Chironomidae: Polypedilum) from China with eleven new species and a supplementary world checklist.

PubMed

Zhang, Ruilei; Song, Chao; Qi, Xin; Wang, Xinhua

2016-07-05

The subgenus Tripodura Townes of Polypedilum Kieffer from China including 26 species is reviewed. Eleven new species, named P. (T.) absensilobum Zhang & Wang sp. n., P. (T.) apiculusetosum Zhang & Wang sp. n., P. (T.) arcuatum Zhang & Wang sp. n., P. (T.) bilamella Zhang & Wang sp. n., P. (T.) conghuaense Zhang & Wang sp. n., P. (T.) dengae Zhang & Wang sp. n., P. (T.) mengmanense Zhang & Wang sp. n., P. (T.) napahaiense Zhang & Wang sp. n., P. (T.) parallelum Zhang & Wang sp. n., P. (T.) pollicium Zhang & Wang sp. n. and P. (T.) trapezium Zhang & Wang sp. n. are described and illustrated based on male imagines. Three species, P. (T.) quadriguttatum Kieffer, P. (T.) unifascia (Tokunaga) and P. (T.) udominutum Niitsuma are firstly recorded in China. A key to known male imagines of Chinese species and an updated world checklist of subgenus Tripodura are presented.

A taxonomic revision of Neoserica (sensu lato): the species groups N. lubrica, N. obscura, and N. silvestris (Coleoptera, Scarabaeidae, Sericini).

PubMed

Liu, Wan-Gang; Fabrizi, Silvia; Bai, Ming; Ahrens, Dirk

2016-01-01

The species of the Neoserica lubrica Brenske, 1898, Neoserica obscura (Blanchard, 1850) and Neoserica silvestris Brenske, 1902 species groups are revised. The study resulted in the following new synonymies and combinations: Neoserica obscura (Blanchard, 1850) = Microserica roeri Frey, 1972, syn. n. , = Maladera chinensis (Arrow, 1946), syn. n. ; Neoserica hainana (Brenske, 1898), comb. n. , and Neoserica minor (Arrow, 1946), comb. n. The known species are redescribed. The following nine new species are described from China: Neoserica allobscura Ahrens, Fabrizi & Liu, sp. n. , Neoserica dongjiafenensis Ahrens, Fabrizi & Liu, sp. n. , Neoserica fugongensis Ahrens, Fabrizi & Liu, sp. n. , Neoserica mantillerii Ahrens, Fabrizi & Liu, sp. n. , Neoserica menglunensis Ahrens, Fabrizi & Liu, sp. n. , Neoserica pseudosilvestris Ahrens, Fabrizi & Liu, sp. n. , Neoserica sakoliana Ahrens, Fabrizi & Liu, sp. n. , Neoserica shuyongi Ahrens, Fabrizi & Liu, sp. n. , and Neoserica tahianensis Ahrens, Fabrizi & Liu, sp. n. A key to the Sericini genera with multilamellate antenna, species groups of Neoserica of mainland Asia, and species of the species groups examined here are provided. Maps of the species distribution are provided, habitus and male genitalia are illustrated.

Bose-Einstein condensate in an optical lattice with Raman-assisted two-dimensional spin-orbit coupling

NASA Astrophysics Data System (ADS)

Pan, Jian-Song; Zhang, Wei; Yi, Wei; Guo, Guang-Can

2016-10-01

In a recent experiment (Z. Wu, L. Zhang, W. Sun, X.-T. Xu, B.-Z. Wang, S.-C. Ji, Y. Deng, S. Chen, X.-J. Liu, and J.-W. Pan, arXiv:1511.08170 [cond-mat.quant-gas]), a Raman-assisted two-dimensional spin-orbit coupling has been realized for a Bose-Einstein condensate in an optical lattice potential. In light of this exciting progress, we study in detail key properties of the system. As the Raman lasers inevitably couple atoms to high-lying bands, the behaviors of the system in both the single- and many-particle sectors are significantly affected. In particular, the high-band effects enhance the plane-wave phase and lead to the emergence of "roton" gaps at low Zeeman fields. Furthermore, we identify high-band-induced topological phase boundaries in both the single-particle and the quasiparticle spectra. We then derive an effective two-band model, which captures the high-band physics in the experimentally relevant regime. Our results not only offer valuable insights into the two-dimensional lattice spin-orbit coupling, but also provide a systematic formalism to model high-band effects in lattice systems with Raman-assisted spin-orbit couplings.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu Wei; Li Hui; Li Shengtai

Nonlinear ideal magnetohydrodynamic (MHD) simulations of the propagation and expansion of a magnetic ''bubble'' plasma into a lower density, weakly magnetized background plasma, are presented. These simulations mimic the geometry and parameters of the Plasma Bubble Expansion Experiment (PBEX) [A. G. Lynn, Y. Zhang, S. C. Hsu, H. Li, W. Liu, M. Gilmore, and C. Watts, Bull. Am. Phys. Soc. 52, 53 (2007)], which is studying magnetic bubble expansion as a model for extragalactic radio lobes. The simulations predict several key features of the bubble evolution. First, the direction of bubble expansion depends on the ratio of the bubble toroidalmore » to poloidal magnetic field, with a higher ratio leading to expansion predominantly in the direction of propagation and a lower ratio leading to expansion predominantly normal to the direction of propagation. Second, a MHD shock and a trailing slow-mode compressible MHD wavefront are formed ahead of the bubble as it propagates into the background plasma. Third, the bubble expansion and propagation develop asymmetries about its propagation axis due to reconnection facilitated by numerical resistivity and to inhomogeneous angular momentum transport mainly due to the background magnetic field. These results will help guide the initial experiments and diagnostic measurements on PBEX.« less

Min Zhang | NREL

Science.gov Websites

Min Zhang Photo of Min Zhang Min Zhang Researcher V-Molecular Biology Min.Zhang@nrel.gov | 303-384 -7753 Research Interests Using a systems biology approach to identify, analyze, and engineer pathways Metabolic engineering Molecular biology Microbial physiology Systems biology Fermentation development Enzyme

A taxonomic revision of Neoserica (sensu lato): the species groups N. lubrica, N. obscura, and N. silvestris (Coleoptera, Scarabaeidae, Sericini)

PubMed Central

Liu, Wan-Gang; Fabrizi, Silvia; Bai, Ming; Ahrens, Dirk

2016-01-01

Abstract The species of the Neoserica lubrica Brenske, 1898, Neoserica obscura (Blanchard, 1850) and Neoserica silvestris Brenske, 1902 species groups are revised. The study resulted in the following new synonymies and combinations: Neoserica obscura (Blanchard, 1850) = Microserica roeri Frey, 1972, syn. n., = Maladera chinensis (Arrow, 1946), syn. n.; Neoserica hainana (Brenske, 1898), comb. n., and Neoserica minor (Arrow, 1946), comb. n. The known species are redescribed. The following nine new species are described from China: Neoserica allobscura Ahrens, Fabrizi & Liu, sp. n., Neoserica dongjiafenensis Ahrens, Fabrizi & Liu, sp. n., Neoserica fugongensis Ahrens, Fabrizi & Liu, sp. n., Neoserica mantillerii Ahrens, Fabrizi & Liu, sp. n., Neoserica menglunensis Ahrens, Fabrizi & Liu, sp. n., Neoserica pseudosilvestris Ahrens, Fabrizi & Liu, sp. n., Neoserica sakoliana Ahrens, Fabrizi & Liu, sp. n., Neoserica shuyongi Ahrens, Fabrizi & Liu, sp. n., and Neoserica tahianensis Ahrens, Fabrizi & Liu, sp. n. A key to the Sericini genera with multilamellate antenna, species groups of Neoserica of mainland Asia, and species of the species groups examined here are provided. Maps of the species distribution are provided, habitus and male genitalia are illustrated. PMID:27917061

Cyanobacterial crust induction using two non-previously tested cyanobacterial inoculants: crusting capability and role of EPSs

NASA Astrophysics Data System (ADS)

Mugnai, Gianmarco; Rossi, Federico; De Philippis, Roberto

2017-04-01

The use of cyanobacteria as soil improvers and bio-conditioners (a technique often referred to as algalization) has been studied for decades. Several studies proved that cyanobacteria are feasible eco-friendly candidates to trigger soil fertilization and enrichment from agricultural to arid and hyper-arid systems. This approach can be successful to achieve stabilization and rehabilitation of degraded environments. Much of the effectiveness of algalization is due to the productivity and the characteristics of extracellular polysaccharides (EPSs) which, among their features, embed soil particles and promote the development of a first stable organo-mineral layer (cyanobacterial crusts). In natural settings, cyanobacterial crust induction represents a first step of a succession that may lead to the formation of mature biological soil crusts (Lan et al., 2014). The aim of this research was to investigate the crusting capabilities, and the characteristics of excreted EPSs by two newly tested non-heterocystous cyanobacterial inoculants, in microcosm experiments carried out using oligothrophic sand collected from sand dunes in Negev Desert, Israel. The cyanobacteria tested were Schizothrix AMPL1601, originally isolated from biocrusts collected in Hobq Desert, Inner Mongolia (China) and Leptolyngbia ohadii, originally isolated from biocrusts collected in Negev Desert, Israel. Inoculated microcosms were maintained at 30 °C in a growth chamber under continuous illumination and minimal water availability. Under such stressing conditions, and for a three-months incubation time, the growth and the colonization of the strains in the microcosms were monitored. At the same time, EPSs production and their chemical and macromolecular characteristics were determined by applying a methodology optimized for the purpose. Notably, EPSs were analyzed in two operationally-defined fractions, one more dispersed in the crust matrix (loosely bound EPSs, LB-EPSs) and one more condensed and stable (tightly bound EPSs, TB-EPSs), which were deemed having different functions (Chen et al., 2014). The results demonstrated how differently (and complementarily in some ways) these two strains behave when applied on a poor sandy substrate, producing cyanobacterial crusts having different morphology. The outcomes of this study suggest the potential of Schizothrix AMPL1601 and Leptolyngbia ohadii as valid biotechnological tools for improving the properties of poor arid soils, allowing to design proper rehabilitation or restoration models. In addition, this study provided new insight on the characteristics of the cyanobacterial EPSs, secreted under a constrained condition, compared to a non-nutrient limited and optimal one. Chen, L., Rossi, F., Deng, S., Liu, Y., Wang, G., Adessi, A., De Philippis, R., 2014. Macromolecular and chemical features of the excreted extracellular polysaccharides in induced biological soil crusts of different ages. Soil Biology and Biochemistry 78, 1-9. doi:10.1016/j.soilbio.2014.07.004 Lan, S., Zhang, Q., Wu, L., Liu, Y., Zhang, D., Hu, C., 2014. Artificially Accelerating the Reversal of Desertification: Cyanobacterial Inoculation Facilitates the Succession of Vegetation Communities. Environmental Science & Technology 48, 307-315. doi:10.1021/es403785j

Investigating the origin of the Chinese name for alfalfa

NASA Astrophysics Data System (ADS)

Sun, Q. Z.; Xu, L. J.; Tang, X. J.; Ma, J. T.; Wang, D.; Li, D.; Liu, Q.; Tao, Y.; Li, F.

2017-02-01

It is assured that alfalfa (Medicago sativa L.) was introduced in Han dynasty. There are cognitive differences on whether Zhang Qian introduced alfalfa. Based on the previous studies, research inductive method was used. The relationship between Zhang Qian and alfalfa introduction was analyzed from the motivation, experience and influence of Zhang Qian to the Western Regions and the image generation of Zhang Qian brought back alfalfa’s seeds. Till to now, there are four opinions about Zhang Qian introducing Alfalfa seeds, including : (1) Zhang Qian introduced alfalfa seeds;(2) Zhang Qian did not introduce alfalfa seeds;(3) the information of Zhang Qian transferring alfalfa;(4)for commemoration Zhang Qian to the Western Regions. Although there are not direct historical materials to support Zhang Qian brought alfalfa seed to Han dynasty, it believes and confirms that the introducing of alfalfa is inextricably interwoven with Zhang Qian’s western travel. Zhangqian brought relative information from western regions during the introduction, which was the basis of non-native theory, and after that, Chinese began to plant alfalfa in Han dynasty., According to historical literatures, it is clear that the Chinese diplomat brought alfalfa seeds back to China. Alfalfa, as the favorite forage to Ferghana horse, have been already planted in Dawan in Han dynasty. Despite the debate, Zhangqian played an important pioneering role in introducing alfalfa.

Review of the genus Pentacentrus Saussure (Orthoptera: Gryllidae: Pentacentrinae) from China .

PubMed

Liu, Hao-Yu; Mao, Shao-Li; Shi, Fu-Ming

2014-07-22

Four new species of Pentacentrus Gorochov from China are described and illustrated, P. acutiparamerus Liu & Shi sp. nov., P. biflexuous Liu & Shi sp. nov., P. emarginatus Liu & Shi sp. nov. and P. parvulus Liu & Shi sp. nov. A key and a distribution map of the Chinese species of this genus are provided.

Tisaniba, a new genus of marpissoid jumping spiders from Borneo (Araneae: Salticidae).

PubMed

Zhang, Jun-Xia; Maddison, Wayne P

2014-08-14

Six new species of marpissoid jumping spiders from Sarawak, Borneo, are described in the new genus Tisaniba Zhang & Maddison. They are the type species, T. mulu Zhang & Maddison sp. nov., as well as the species T. bijibijan Zhang & Maddison sp. nov., T. dik Zhang & Maddison sp. nov., T. kubah Zhang & Maddison sp. nov., T. selan Zhang & Maddison sp. nov., and T. selasi Zhang & Maddison sp. nov. The spiders are small and brown to black, living in leaf litter in the tropical forest. Phylogenetic analyses based on 28s and 16sND1 genes indicate that they are a distinctive group within the marpissoids. Diagnostic illustrations and photographs of living spiders are provided for all species.

Two Analogous Polyhedron-Based MOFs with High Density of Lewis Basic Sites and Open Metal Sites: Significant CO2 Capture and Gas Selectivity Performance.

PubMed

Liu, Bing; Yao, Shuo; Liu, Xinyao; Li, Xu; Krishna, Rajamani; Li, Guanghua; Huo, Qisheng; Liu, Yunling

2017-09-27

By means of modulating the axial ligand and adopting supermolecular building blocks (SBBs) strategy, two polyhedron-based metal-organic frameworks (PMOFs) have been successfully synthesized [Cu 6 (C 17 O 9 N 2 H 8 ) 3 (C 6 H 12 N 2 )(H 2 O) 2 (DMF) 2 ]·3DMF·8H 2 O (JLU-Liu46) and [Cu 6 (C 17 O 9 N 2 H 8 ) 3 (C 4 H 4 N 2 )(H 2 O) 2 (DMF) 2 ]·3DMF·8H 2 O (JLU-Liu47), which possess a high density of Lewis basic sites (LBSs) and open metal sites (OMSs). Since the size of axial ligand in JLU-Liu47 is smaller than that in JLU-Liu46, JLU-Liu47 shows larger pore volume and higher BET surface area. Then, the adsorption ability of JLU-Liu47 for some small gases is better than JLU-Liu46. It is worthwhile to mention that both of the two compounds exhibit outstanding adsorption capability for CO 2 ascribed to the introducing of urea groups. In addition, the theoretical ideal adsorbed solution theory (IAST) calculation and transient breakthrough simulation indicate that JLU-Liu46 and JLU-Liu47 should be potential materials for gas storage and separation, particularly for CO 2 /N 2 , CO 2 /CH 4 , and C 3 H 8 /CH 4 separation.

De novo characterization of the pine aphid Cinara pinitabulaeformis Zhang et Zhang transcriptome and analysis of genes relevant to pesticides

PubMed Central

Rebeca, Carballar-Lejarazú; Zhu, Xiaoli; Guo, Yajie; Lin, Qiannan; Hu, Xia; Wang, Rong; Liang, Guanghong; Guan, Xiong

2017-01-01

The pine aphid Cinara pinitabulaeformis Zhang et Zhang is the main pine pest in China, it causes pine needles to produce dense dew (honeydew) which can lead to sooty mold (black filamentous saprophytic ascomycetes). Although common chemical and physical strategies are used to prevent the disease caused by C. pinitabulaeformis Zhang et Zhang, new strategies based on biological and/or genetic approaches are promising to control and eradicate the disease. However, there is no information about genomics, proteomics or transcriptomics to allow the design of new control strategies for this pine aphid. We used next generation sequencing technology to sequence the transcriptome of C. pinitabulaeformis Zhang et Zhang and built a transcriptome database. We identified 80,259 unigenes assigned for Gene Ontology (GO) terms and information for a total of 11,609 classified unigenes was obtained in the Clusters of Orthologous Groups (COGs). A total of 10,806 annotated unigenes were analyzed to identify the represented biological pathways, among them 8,845 unigenes matched with 228 KEGG pathways. In addition, our data describe propagative viruses, nutrition-related genes, detoxification related molecules, olfactory related receptors, stressed-related protein, putative insecticide resistance genes and possible insecticide targets. Moreover, this study provides valuable information about putative insecticide resistance related genes and for the design of new genetic/biological based strategies to manage and control C. pinitabulaeformis Zhang et Zhang populations. PMID:28570707

Thermal Resistances in the Everest Area derived from Satellite Imagery using a Nonlinear Energy Balance Model

NASA Astrophysics Data System (ADS)

Rounce, D.; McKinney, D. C.

2013-12-01

Debris cover has a large impact on sub-debris ablation rates and glacier evolution. A thin debris layer may enhance ablation by reducing albedo increasing radiation absorption, while thicker debris insulates the glacier causing ablation to decrease. Debris thickness, thermal conductivity, and meteorological conditions may be measured in the field, but they require extensive fieldwork (Brock et al., 2010; Nicholson and Benn, 2012). This has forced many simplifications and assumptions in models. Satellite imagery combined with an energy balance model has been used with to extract information about debris cover remotely (Nakawo and Rana, 1999; Zhang et al., 2011). The spatial distribution of thermal resistances derived from these studies have agreed well with field values; however, the values were considerably lower than the field values. The difference has been attributed to the mixed pixel effect. Foster et al. (2012) developed an energy balance model that agrees well with debris thickness measured in the field. The model requires knowledge of the thermal conductivity and utilizes a relationship between air and surface temperature to lower sensible heat fluxes. We derive thermal resistances of debris-covered glaciers from satellite imagery in the Everest area. Previous satellite studies have assumed a linear debris temperature gradient, which is valid for time periods of 24 hours or greater (Nicholson and Benn, 2006); however, gradients during the day are nonlinear (Nicholson and Benn, 2006; Reid and Brock, 2010). Landsat 7 imagery is used to account for the non-linear gradient, using the ratio of temperature gradient in the upper 10cm versus the entire debris thickness. These values are derived from temperature profiles on Ngozumpa Glacier (Nicholson, 2004). Meteorological data are obtained from the Pyramid Station. The derived thermal resistances agree well with those found on debris-covered glaciers in the Everest region. Brock, B., Mihalcea, C., Kirkbride, M., Diolaiuti, G., Cutler, M., Smiraglia, C. Meteorology and surface energy fluxes in the 2005-2007 ablation seasons at the Miage debris-covered glacier. J. Geoph. Res., 115, 2010 Foster, L., Brock, B., Cutler, M., Diotri, F. A physically based method for estimating supraglacial debris thickness from thermal band remote-sensing data. J. Glaciol. 58(210):677-691, 2012 Nakawo, M., Rana, B. Estimate of Ablation Rate of Glacier Ice Under a Supraglacial Debris Layer. Geografiska Annaler 81(4):695-701, 1999 Nicholson, L. Modelling melt beneath supraglacial debris: implications for the climatic response of debris-covered glaciers. PhD thesis, Univ. of St Andrews, 2004 Nicholson, L., Benn, D. Calculating ice melt beneath a debris layer using meteorological data. J. Glaciol. 52(178):463-470, 2006 Nicholson, L., Benn, D. Properties of Natural Supraglacial Debris in Relation to Modelling Sub-Debris Ice Ablation. Earth Surf. Proc. and Landforms 38(5):490-501, 2012 Reid, T., Brock, B. An Energy-Balance Model for Debris-Covered Glaciers Including Heat Conduction through the Debris Layer. J. Glaciol. 56(199):903-916, 2010 Zhang, Y., Fujita, K., Liu, S., Liu, Q., Nuimura, T. Distribution of Debris Thickness and its Effect on Ice Melt at Hailuogou Glacier. J. Glaciol. 57(206):1147-1157, 2011

Phase equilibria modelling and zircon dating for Precambrian metapelites from Xinghuadukou Group in Lvlin Forest of Erguna Massif, NE China

NASA Astrophysics Data System (ADS)

Xu, Jiulei; Zheng, Changqing; Tajcmanova, Lucie; Zhong, Xin; Xu, Xuechun; Han, Xiaomeng; Wang, Zhaoyuan

2017-04-01

Xinghuadukou Group, the basement metamorphic complex of Erguna Massif in NE China, is considered to be Mesoproterozoic with Sm-Nd age of 1157±32 Ma. However, the new zircon data from these metamorphic supracrustal rocks in Lvlin Forest show that they formed in Neoproterozoic with the age of 800 Ma. Old zircon age with 2.5 Ga, 2.0 Ga and 1.8 Ga, indicate that the Erguna Massif had an affinity to both Columbia and Rodinia continents. Furthermore, we also present 500 Ma metamorphic age in micashists and 500 Ma age of adjacent granitoids that might have thermally influenced its surrounding. No detailed studies have been undertaken on the metamorphic evolution of the Xinghuadukou Complex. The typical paragneissic mineral assemblage of garnet sillimanite mica schist is Grt+Sil+Bt+Mus+Qtz±Kfs. (Zhou et al., 2011) proposed that the Xinghuadukou Complex appears to have undergone similar granulite facies metamorphic conditions based on the similarity of mineral assemblages to the Mashan Complex in the Jiamusi Massif, NE China. However, the new phase equilibria modelling result shows that these rocks are high amphibolite facies product with 650℃. We can easily find K-feldspar formed by partial melting due to the consuming of muscovite. Also the remaining muscovite is directly connected with a fluid channel in thin sections which indicate that the remaining muscovite formed from retrograde with the existence of fluid. The zoned garnet has low MgO and high CaO content in rims and high MgO and low CaO content in core. It seems that this garnet has high pressure and low temperature (HP-LT) in rims and low pressure and high temperature (LP-HT) in core which would point to an anti-clockwise metamorphic evolution. Zhou, J.B., Wilde, S.A., Zhang, X.Z., Zhao, G.C., Liu, F.L., Qiao, D.W., Ren, S.M. and Liu, J.H., 2011b. A> 1300km late Pan-African metamorphic belt in NE China: new evidence from the Xing'an block and its tectonic implications. Tectonophysics, 509(3): 280-292.

Wave propagation, scattering and emission in complex media

NASA Astrophysics Data System (ADS)

Jin, Ya-Qiu

I. Polarimetric scattering and SAR imagery. EM wave propagation and scattering in polarimetric SAR interferometry / S. R. Cloude. Terrain topographic inversion from single-pass polarimetric SAR image data by using polarimetric stokes parameters and morphological algorithm / Y. Q. Jin, L. Luo. Road detection in forested area using polarimetric SAR / G. W. Dong ... [et al.]. Research on some problems about SAR radiometric resolution / G. Dong ... [et al.]. A fast image matching algorithm for remote sensing applications / Z. Q. Hou ... [et al.]. A new algorithm of noised remote sensing image fusion based on steerable filters / X. Kang ... [et al.]. Adaptive noise reduction of InSAR data based on anisotropic diffusion models and their applications to phase unwrapping / C. Wang, X. Gao, H. Zhang -- II. Scattering from randomly rough surfaces. Modeling tools for backscattering from rough surfaces / A. K. Fung, K. S. Chen. Pseudo-nondiffracting beams from rough surface scattering / E. R. Méndez, T. A. Leskova, A. A. Maradudin. Surface roughness clutter effects in GPR modeling and detection / C. Rappaport. Scattering from rough surfaces with small slopes / M. Saillard, G. Soriano. Polarization and spectral characteristics of radar signals reflected by sea-surface / V. A. Butko, V. A. Khlusov, L. I. Sharygina. Simulation of microwave scattering from wind-driven ocean surfaces / M. Y. Xia ... [et al.]. HF surface wave radar tests at the Eastern China Sea / X. B. Wu ... [et al.] -- III. Electromagnetics of complex materials. Wave propagation in plane-parallel metamaterial and constitutive relations / A. Ishimaru ... [et al.]. Two dimensional periodic approach for the study of left-handed metamaterials / T. M. Grzegorczyk ... [et al.]. Numerical analysis of the effective constitutive parameters of a random medium containing small chiral spheres / Y. Nanbu, T. Matsuoka, M. Tateiba. Wave propagation in inhomogeneous media: from the Helmholtz to the Ginzburg -Landau equation / M. Gitterman. Transformation of the spectrum of scattered radiation in randomly inhomogeneous absorptive plasma layer / G. V. Jandieri, G. D. Aburjunia, V. G. Jandieri. Numerical analysis of microwave heating on saponification reaction / K. Huang, K. Jia -- IV. Scattering from complex targets. Analysis of electromagnetic scattering from layered crossed-gratings of circular cylinders using lattice sums technique / K. Yasumoto, H. T. Jia. Scattering by a body in a random medium / M. Tateiba, Z. Q. Meng, H. El-Ocla. A rigorous analysis of electromagnetic scattering from multilayered crossed-arrays of metallic cylinders / H. T. Jia, K. Yasumoto. Vector models of non-stable and spatially-distributed radar objects / A. Surkov ... [et al.]. Simulation of algorithm of orthogonal signals forming and processing used to estimate back scattering matrix of non-stable radar objects / D. Nosov ... [et al.]. New features of scattering from a dielectric film on a reflecting metal substrate / Z. H. Gu, I. M. Fuks, M. Ciftan. A higher order FDTD method for EM wave propagation in collision plasmas / S. B. Liu, J. J. Mo, N. C. Yuan -- V. Radiative transfer and remote sensing. Simulating microwave emission from Antarctica ice sheet with a coherent model / M. Tedesco, P. Pampaloni. Scattering and emission from inhomogeneous vegetation canopy and alien target by using three-dimensional Vector Radiative Transfer (3D-VRT) equation / Y. Q. Jin, Z. C. Liang. Analysis of land types using high-resolution satellite images and fractal approach / H. G. Zhang ... [et al.]. Data fusion of RADARSAT SAR and DMSP SSM/I for monitoring sea ice of China's Bohai Sea / Y. Q. Jin. Retrieving atmospheric temperature profiles from simulated microwave radiometer data with artificial neural networks / Z. G. Yao, H. B. Chen -- VI. Wave propagation and wireless communication. Wireless propagation in urban environments: modeling and experimental verification / D. Erricolo ... [et al.]. An overview of physics-based wave propagation in forested environment / K. Sarabandi, I. Koh. Angle-of-arrival fluctuations due to meteorological conditions in the diffraction zone of C-band radio waves, propagated over the ground surface / T. A. Tyufilina, A. A. Meschelyakov, M. V. Krutikov. Simulating radio channel statistics using ray based prediction codes / H. L. Bertoni. Measurement and simulation of ultra wideband antenna elements / W. Sörgel, W. Wiesbeck. The experimental investigation of a ground-placed radio complex synchronization system / V. P. Denisov ... [et al.] -- VII. Computational electromagnetics. Analysis of 3-D electromagnetic wave scattering with the Krylov subspace FFT iterative methods / R. S. Chen ... [et al.]. Sparse approximate inverse preconditioned iterative algorithm with block toeplitz matrix for fast analysis of microstrip circuits / L. Mo, R. S. Chen, E. K. N. Yung. An Efficient modified interpolation technique for the translation operators in MLFMA / J. Hu, Z. P. Nie, G. X. Zou. Efficient solution of 3-D vector electromagnetic scattering by CG-MLFMA with partly approximate iteration / J. Hu, Z. P. Nie. The effective constitution at interface of different media / L. G. Zheng, W. X. Zhang. Novel basis functions for quadratic hexahedral edge element / P. Liu ... [et al.]. A higher order FDTD method for EM wave propagation in collision plasmas / S. B. Liu, J. J. Mo, N. C. Yuan. Attenuation of electric field eradiated by underground source / J. P. Dong, Y. G. Gao.

An Analysis of Navy Nurse Corps Accession Sources

DTIC Science & Technology

2014-03-01

1 I. INTRODUCTION A. BACKGROUND Since 1998, the United States has experienced a nationwide nursing shortage (Juraschek, Zhang, Ranganathan ...supply of RNs in the civilian workforce (Juraschek, Zhang, Ranganathan , & Lin, 2012). A study by Juraschek, Zhang, Ranganathan , & Lin (2012...Postgraduate School, Monterey, CA. Retrieved from www.dtic.mil/cgi- bin/GetTRDoc?AD=ADA344570 Juraschek, S. P., Zhang, X., Ranganathan , V. K., & Lin, V

Mobile Device-Based Electronic Data Capture System Used in a Clinical Randomized Controlled Trial: Advantages and Challenges.

PubMed

Zhang, Jing; Sun, Lei; Liu, Yu; Wang, Hongyi; Sun, Ningling; Zhang, Puhong

2017-03-08

Electronic data capture (EDC) systems have been widely used in clinical research, but mobile device-based electronic data capture (mEDC) system has not been well evaluated. The aim of our study was to evaluate the feasibility, advantages, and challenges of mEDC in data collection, project management, and telemonitoring in a randomized controlled trial (RCT). We developed an mEDC to support an RCT called "Telmisartan and Hydrochlorothiazide Antihypertensive Treatment (THAT)" study, which was a multicenter, double-blinded, RCT, with the purpose of comparing the efficacy of telmisartan and hydrochlorothiazide (HCTZ) monotherapy in high-sodium-intake patients with mild to moderate hypertension during a 60 days follow-up. Semistructured interviews were conducted during and after the trial to evaluate the feasibility, advantage, and challenge of mEDC. Nvivo version 9.0 (QSR International) was used to analyze records of interviews, and a thematic framework method was used to obtain outcomes. The mEDC was successfully used to support the data collection and project management in all the 14 study hospitals. A total of 1333 patients were recruited with support of mEDC, of whom 1037 successfully completed all 4 visits. Across all visits, the average time needed for 141 questions per patient was 53 min, which were acceptable to both doctors and patients. All the interviewees, including 24 doctors, 53 patients, 1 clinical research associate (CRA), 1 project manager (PM), and 1 data manager (DM), expressed their satisfaction to nearly all the functions of the innovative mEDC in randomization, data collection, project management, quality control, and remote monitoring in real time. The average satisfaction score was 9.2 (scale, 0-10). The biggest challenge came from the stability of the mobile or Wi-Fi signal although it was not a problem in THAT study. The innovative mEDC has many merits and is well acceptable in supporting data collection and project management in a timely manner in clinical trial. ©Jing Zhang, Lei Sun, Yu Liu, Hongyi Wang, Ningling Sun, Puhong Zhang. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.03.2017.

A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel.

PubMed

Tang, Cheng; Zhou, Xi; Nguyen, Phuong Tran; Zhang, Yunxiao; Hu, Zhaotun; Zhang, Changxin; Yarov-Yarovoy, Vladimir; DeCaen, Paul G; Liang, Songping; Liu, Zhonghua

2017-07-01

Voltage-gated sodium channels (Na V s) are activated by transiting the voltage sensor from the deactivated to the activated state. The crystal structures of several bacterial Na V s have captured the voltage sensor module (VSM) in an activated state, but structure of the deactivated voltage sensor remains elusive. In this study, we sought to identify peptide toxins stabilizing the deactivated VSM of bacterial Na V s. We screened fractions from several venoms and characterized a cystine knot toxin called JZTx-27 from the venom of tarantula Chilobrachys jingzhao as a high-affinity antagonist of the prokaryotic Na V s Ns V Ba (nonselective voltage-gated Bacillus alcalophilus ) and NaChBac (bacterial sodium channel from Bacillus halodurans ) (IC 50 = 112 nM and 30 nM, respectively). JZTx-27 was more efficacious at weaker depolarizing voltages and significantly slowed the activation but accelerated the deactivation of Ns V Ba, whereas the local anesthetic drug lidocaine was shown to antagonize Ns V Ba without affecting channel gating. Mutation analysis confirmed that JZTx-27 bound to S3-4 linker of Ns V Ba, with F98 being the critical residue in determining toxin affinity. All electrophysiological data and in silico analysis suggested that JZTx-27 trapped VSM of Ns V Ba in one of the deactivated states. In mammalian Na V s, JZTx-27 preferably inhibited the inactivation of Na V 1.5 by targeting the fourth transmembrane domain. To our knowledge, this is the first report of peptide antagonist for prokaryotic Na V s. More important, we proposed that JZTx-27 stabilized the Ns V Ba VSM in the deactivated state and may be used as a probe to determine the structure of the deactivated VSM of Na V s.-Tang, C., Zhou, X., Nguyen, P. T., Zhang, Y., Hu, Z., Zhang, C., Yarov-Yarovoy, V., DeCaen, P. G., Liang, S., Liu, Z. A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel. © FASEB.

The late Miocene 'paradox' of the CO2 climate sensitivity (Invited)

NASA Astrophysics Data System (ADS)

Zhang, Y.; Pagani, M.

2013-12-01

Ancient climates provide opportunities for studying the impact of CO2 change on global temperatures. While advances in CO2-reconstruction techniques are yielding a clearer picture of the Cenozoic history of CO2 (Beerling and Royer, 2011), the late Miocene (~12-5 Ma) remains enigmatic. For example, recent sea-surface temperature reconstructions from 12-5 Ma have shown that mid-latitude and equatorial regions of the Pacific cooled 6°C (LaRiviere et al., 2012) and 2°C (Zhang et al., 2013), respectively. This cooling trend was probably initiated at the mid-Miocene climate transition (14 Ma), and continued into the Plio-Pleistocene. However, existing compilation of late Miocene - Pliocene CO2 records show little variability, with some indicating a rise in CO2 concurrent with global cooling. Here we present four continuous alkenone-based CO2 records using Pacific sediment samples (ODP Sites 769, 806, 850 and 1143), from late Miocene to Pliocene. Compound-specific carbon isotope measurements show a broad decrease in alkenone δ13C values in all four sites, suggesting increasing pCO2 levels in the late Miocene. Decreasing ocean temperature and increasing pCO2 in the late Miocene appears to challenge a leading climatic role for CO2 during this time. Alternatively, alkenone-CO2 estimates are flawed in the late Miocene because factors other than CO2, such as algal growth rate, cell geometry, and carbon-fixation pathways, can influence carbon isotopic fractionation during algae growth. We explore the uncertainty of the alkenone-CO2 methodology and assess the potential influence that non-CO2 variables have in producing spurious CO2 estimates and trends. Beerling, D.J., Royer, D.L., 2011. Convergent Cenozoic CO2 history. Nat. Geosci. 4, 418-420. LaRiviere, J.P., Ravelo, A.C., Crimmins, A., Dekens, P.S., Ford, H.L., Lyle, M., Wara, M.W., 2012. Late Miocene decoupling of oceanic warmth and atmospheric carbon dioxide forcing. Nature 486, 97-100. Zhang, Y.G., Pagani, M., Liu, Z., 2013. Temperature evolution of the equatorial Pacific since late Miocene and the ancient El Nino. In Preperation.

Creating Knowledge

ERIC Educational Resources Information Center

Cline, Kimberly R.

2015-01-01

Long Island University's (LIU) honors programs were founded during a decade that gave rise to honors programs nationally. The LIU Post Honors Program was one of the first in 1963 after the University of Michigan LSA Honors Program in 1957 and the Echols Scholars Program at the University of Virginia in 1960; the LIU Brooklyn University Honors…

The atu and liu clusters are involved in the catabolic pathways for acyclic monoterpenes and leucine in Pseudomonas aeruginosa.

PubMed

Aguilar, J A; Zavala, A N; Díaz-Pérez, C; Cervantes, C; Díaz-Pérez, A L; Campos-García, J

2006-03-01

Evidence suggests that the Pseudomonas aeruginosa PAO1 gnyRDBHAL cluster, which is involved in acyclic isoprenoid degradation (A. L. Díaz-Pérez, N. A. Zavala-Hernández, C. Cervantes, and J. Campos-García, Appl. Environ. Microbiol. 70:5102-5110, 2004), corresponds to the liuRABCDE cluster (B. Hoschle, V. Gnau, and D. Jendrossek, Microbiology 151:3649-3656, 2005). A liu (leucine and isovalerate utilization) homolog cluster was found in the PAO1 genome and is related to the catabolism of acyclic monoterpenes of the citronellol family (AMTC); it was named the atu cluster (acyclic terpene utilization), consisting of the atuCDEF genes and lacking the hydroxymethyl-glutaryl-coenzyme A (CoA) lyase (HMG-CoA lyase) homolog. Mutagenesis of the atu and liu clusters showed that both are involved in AMTC and leucine catabolism by encoding the enzymes related to the geranyl-CoA and the 3-methylcrotonyl-CoA pathways, respectively. Intermediary metabolites of the acyclic monoterpene pathway, citronellic and geranic acids, were accumulated, and leucine degradation rates were affected in both atuF and liuD mutants. The alpha subunit of geranyl-CoA carboxylase and the alpha subunit of 3-methylcrotonyl-CoA carboxylase (alpha-MCCase), encoded by the atuF and liuD genes, respectively, were both induced by citronellol, whereas only the alpha-MCCase subunit was induced by leucine. Both citronellol and leucine also induced a LacZ transcriptional fusion at the liuB gene. The liuE gene encodes a probable hydroxy-acyl-CoA lyase (probably HMG-CoA lyase), an enzyme with bifunctional activity that is essential for both AMTC and leucine degradation. P. aeruginosa PAO1 products encoded by the liuABCD cluster showed a higher sequence similarity (77.2 to 79.5%) with the probable products of liu clusters from several Pseudomonas species than with the atuCDEF cluster from PAO1 (41.5%). Phylogenetic studies suggest that the atu cluster from P. aeruginosa could be the result of horizontal transfer from Alphaproteobacteria. Our results suggest that the atu and liu clusters are bifunctional operons involved in both the AMTC and leucine catabolic pathways.

New name, fiaxtion of correct spelling of three leafhopper taxa (Hemiptera: Cicadellidae)

USDA-ARS?s Scientific Manuscript database

The leafhopper genus Aspidia Yang & Zhang is a junior homonym and replaced here by Sochinsogonoidea, nomen novum. Nilgiriscopus Viraktamath and Roxasellana stellata Zhang & Zhang are fixed as the correct original spellings....

A pilot study using the Chinese herbal paste Liu-He-Dan to manage radiodermatitis associated with breast cancer radiotherapy.

PubMed

Zhou, J; Fang, L; Xie, H; Yao, W X; Zhou, X; Xiong, Z J

2015-12-01

During radiotherapy for breast cancer, patients are greatly affected by pain, infection, and delayed healing of wounds caused by radiodermatitis. In the present study, we aimed to determine the efficacy of Liu-He-Dan in treating radiodermatitis. In 26 breast cancer patients who experienced moist decrustation while receiving radiotherapy, 5 g Liu-He-Dan was applied externally once daily after the wound surface had been cleaned and dried. The healing time was recorded, and a Kaplan-Meier survival curve was applied to analyze the treatment course. Meanwhile, a pain assessment using the Numeric Rating Scale (nrs) recorded the pain level experienced by patients after application of the Liu-He-Dan. After application of Liu-He-Dan, the average healing time for the surface of the moist decrustation wounds was 14.17 ± 2.03 days (range: 5-22 days). Inflammatory seepage decreased significantly and exudation almost disappeared in 3 days. The pain trend line indicated that the average nrs score declined with treatment in all patients. The average nrs scores at days 1, 4, and 7 were 6.13, 3.62, and 2.58 respectively. After 3 days of treatment, pain was remarkably alleviated in 80.76% of patients. After treatment for 1 week, the pain remission rate was 96.15%, without any obvious adverse reactions. Liu-He-Dan was efficacious in treating radiation skin injury with little toxicity and few side effects; the economic efficiency of the treatment was also favourable. The Liu-He-Dan was generally well tolerated by patients. In future, randomized control trials will be established for further observation of the value of Liu-He-Dan in treating radiodermatitis in breast cancer.

Myricetin: a potent approach for the treatment of type 2 diabetes as a natural class B GPCR agonist

PubMed Central

Li, Ying; Zheng, Xuemin; Yi, Xiulin; Liu, Changxiao; Kong, Dexin; Zhang, Jianning; Gong, Min

2017-01-01

The physiologic properties of glucagon-like peptide 1 (GLP-1) make it a potent candidate drug target in the treatment of type 2 diabetes mellitus (T2DM). GLP-1 is capable of regulating the blood glucose level by insulin secretion after administration of oral glucose. The advantages of GLP-1 for the avoidance of hypoglycemia and the control of body weight are attractive despite its poor stability. The clinical efficacies of long-acting GLP-1 derivatives strongly support discovery pursuits aimed at identifying and developing orally active, small-molecule GLP-1 receptor (GLP-1R) agonists. The purpose of this study was to identify and characterize a novel oral agonist of GLP-1R (i.e., myricetin). The insulinotropic characterization of myricetin was performed in isolated islets and in Wistar rats. Long-term oral administration of myricetin demonstrated glucoregulatory activity. The data in this study suggest that myricetin might be a potential drug candidate for the treatment of T2DM as a GLP-1R agonist. Further structural modifications on myricetin might improve its pharmacology and pharmacokinetics.—Li, Y., Zheng, X., Yi, X., Liu, C., Kong, D., Zhang, J., Gong, M. Myricetin: a potent approach for the treatment of type 2 diabetes as a natural class B GPCR agonist. PMID:28270518

A new name and seventeen new combinations in the Magnolia (Magnoliaceae) of China and Vietnam.

PubMed

Callaghan, Chris; Png, Siak-Khoon Sk

2013-12-01

A new name is proposed and seventeen new combinations are made as a result of the previous reduction of the remaining genera of subfamily Magnolioideae (Magnoliaceae) into the genus Magnolia. The replacement name Magnolia fansipanensis is proposed for Manglietia crassifolia Q. N. Vu et al., since its transfer to Magnolia would create an illegitimate later homonym of the fossil name M. crassifolia Göpp. A further 17 new combinations are made to transfer the following taxa to Magnolia: Manglietia guangzhouensis A. Q. Dong et al., M. kaifui Q. W. Zeng & X. M. Hu, M. lawii N. H. Xia & W. F. Liao, plus Michelia concinna H. Jiang & E. D. Liu, M. jianfenglingensis G. A. Fu & K. Pan, M. viridipetala Y. W. Law et al., M. wuzhishangensis G. A. Fu & K. Pan, M. xianianhei Q. N. Vu and Yulania carnosa D. L. Fu & D. L. Zhang, Y. cuneatofolia T. B. Chao (probably Zhao) et al., Y. dabieshanensis T. B. Zhao et al., Y. dimorpha T. B. Zhao & Z. X. Chen, Y. fragarigynandria T. B. Zhao et al., Y. shirenshanensis D. L. Fu & T. B. Zhao, Y. shizhenii D. L. Fu & F. W. Li, Y. verrucata D. L. Fu et al. and Y. xinyangensis T. B. Zhao et al. The transfer of the above taxa to Magnolia is necessary following the present almost universal recognition of Magnolioideae as one of two monogeneric subfamilies within Magnoliaceae.

Delphi Study of Instructional Strategies for English Language Learners with Disabilities: Recommendations from Educators Nationwide. ELLs with Disabilities Report 21

ERIC Educational Resources Information Center

Thurlow, Martha; Shyyan, Vitaliy; Barrera, Manuel; Liu, Kristi

2008-01-01

This study is part of national research over the past seven years at the National Center on Educational Outcomes focused on identifying and validating instructional strategies for ELLs with disabilities (Shyyan, Thurlow, & Liu, 2008; Thurlow, Albus, Shyyan, Liu, & Barrera, 2004). In recent work (Barrera, Shyyan, Liu, & Thurlow, 2008),…

Clar theory and resonance energy

NASA Astrophysics Data System (ADS)

Gutman, Ivan; Gojak, Sabina; Furtula, Boris

2005-09-01

A mathematical model, referred here as the Zhang-Zhang polynomial ζ( x), that embraces all the main concepts encountered in the Clar aromatic sextet theory of benzenoid hydrocarbons, was recently put forward by Zhang and Zhang. We now show that ζ( x) is related to resonance energy, and that ln ζ( x) and RE are best correlated when x ≈ 1. This indicates that ζ(1) could be viewed as a (novel) structure-descriptor, playing a role analogous to the Kekulé structure count in Kekulé-structure-based theories. Some basic properties of ζ(1) are established.

Hybrid Chaos Synchronization of Four-Scroll Systems via Active Control

NASA Astrophysics Data System (ADS)

Karthikeyan, Rajagopal; Sundarapandian, Vaidyanathan

2014-03-01

This paper investigates the hybrid chaos synchronization of identical Wang four-scroll systems (Wang, 2009), identical Liu-Chen four-scroll systems (Liu and Chen, 2004) and non-identical Wang and Liu-Chen four-scroll systems. Active control method is the method adopted to achieve the hybrid chaos synchronization of the four-scroll chaotic systems addressed in this paper and our synchronization results are established using Lyapunov stability theory. Since the Lyapunov exponents are not required for these calculations, the active control method is effective and convenient to hybrid synchronize identical and different Wang and Liu-Chen four-scroll chaotic systems. Numerical simulations are also shown to illustrate and validate the hybrid synchronization results derived in this paper.

[Textual research of Liu Wan-su's works on consumptive thirst].

PubMed

Yang, Shi-Zhe; Zhang, Xian-Zhe

2007-07-01

Liu Wan-su's San xiao lun (On Three Consumptions) was the earliest extant monograph dealing with the consumption thirst in traditional Chinese medicine (TCM). The other book, with the namesake of Liu Wan-su, Su wen bing ji qi yi bao ming ji (Collection for Preserving Life of Pathogenesis in Plain Questions), also included a section of consumption thirst. However, through comparison, the descriptions in both books were quite different and it seemed unlikely that it were written by the same author. Based on textural research of bibliography, it's hard to say if this is a true one. Further, comparison of the book with the texts of consumption thirst in Huang di su wen xuan ming lun fang (Elucidated Prescriptions and Expositions of Huangdi's Plain Questions), an authentic book of Liu, a consistency was found between San xiao lun and Huang di su wen xuan ming lun fang. It is very unlikely that Su wen bing ji qi yi bao ming ji was written by Liu because of its obvious different writing style.

The Effects of Small Sample Size on Identifying Polytomous DIF Using the Liu-Agresti Estimator of the Cumulative Common Odds Ratio

ERIC Educational Resources Information Center

Carvajal, Jorge; Skorupski, William P.

2010-01-01

This study is an evaluation of the behavior of the Liu-Agresti estimator of the cumulative common odds ratio when identifying differential item functioning (DIF) with polytomously scored test items using small samples. The Liu-Agresti estimator has been proposed by Penfield and Algina as a promising approach for the study of polytomous DIF but no…

DCIS-Specific MicroRNA in Cancer Stem Cell

DTIC Science & Technology

2011-09-01

Gairani, Misako Watabe, Fei Xing, Aya Kobayashi, Wen Liu, Koji Fukuda, , Sudha Pai and Kounosuke Watabe. Roles of lipogenesis and microRNA in cancer...Pai, Wen Liu, Aya Kobayashi, Fei Xing, Koji Fukuda , Shigeru Hirota, Tamotsu Sugai, Go Wakabayashi, Keisuke Koeda, Masahiro Kashiwaba, Kazuyuki...Aya Kobayashi, Wen Liu, Koji Fukuda, , Sudha Pai and Kounosuke Watabe Roles of lipogenesis and microRNA in cancer stem- like cells in ductal carcinoma

Manufacture of probiotic Minas Frescal cheese with Lactobacillus casei Zhang.

PubMed

Dantas, Aline B; Jesus, Vitor F; Silva, Ramon; Almada, Carine N; Esmerino, E A; Cappato, Leandro P; Silva, Marcia C; Raices, Renata S L; Cavalcanti, Rodrigo N; Carvalho, Celio C; Sant'Ana, Anderson S; Bolini, Helena M A; Freitas, Monica Q; Cruz, Adriano G

2016-01-01

In this study, the addition of Lactobacillus casei Zhang in the manufacture of Minas Frescal cheese was investigated. Minas Frescal cheeses supplemented with probiotic bacteria (Lactobacillus casei Zhang) were produced by enzymatic coagulation and direct acidification and were subjected to physicochemical (pH, proteolysis, lactic acid, and acetic acid), microbiological (probiotic and lactic bacteria counts), and rheological analyses (uniaxial compression and creep test), instrumental color determination (luminosity, yellow intensity, and red intensity) and sensory acceptance test. The addition of L. casei Zhang resulted in low pH values and high proteolysis indexes during storage (from 5.38 to 4.94 and 0.470 to 0.702, respectively). Additionally, the cheese protocol was not a hurdle for growth of L. casei Zhang, as the population reached 8.16 and 9.02 log cfu/g by means of the direct acidification and enzymatic coagulation protocol, respectively, after 21 d of refrigerated storage. The rheology data showed that all samples presented a more viscous-like behavior, which rigidity tended to decrease during storage and lower luminosity values were also observed. Increased consumer acceptance was observed for the control sample produced by direct acidification (7.8), whereas the cheeses containing L. casei Zhang presented lower values for all sensory attributes, especially flavor and overall liking (5.37 and 4.61 for enzymatic coagulation and 5.57 and 4.72 for direct acidification, respectively). Overall, the addition of L. casei Zhang led to changes in all parameters and affected negatively the sensory acceptance. The optimization of L. casei Zhang dosage during the manufacturing of probiotic Minas Frescal cheese should be performed. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

PREFACE: International Conference on Inverse Problems 2010

NASA Astrophysics Data System (ADS)

Hon, Yiu-Chung; Ling, Leevan

2011-03-01

Following the first International Conference on Inverse Problems - Recent Theoretical Development and Numerical Approaches held at the City University of Hong Kong in 2002, the fifth International Conference was held again at the City University during December 13-17, 2010. This fifth conference was jointly organized by Professor Yiu-Chung Hon (Co-Chair, City University of Hong Kong, HKSAR), Dr Leevan Ling (Co-Chair, Hong Kong Baptist University, HKSAR), Professor Jin Cheng (Fudan University, China), Professor June-Yub Lee (Ewha Womans University, South Korea), Professor Gui-Rong Liu (University of Cincinnati, USA), Professor Jenn-Nan Wang (National Taiwan University, Taiwan), and Professor Masahiro Yamamoto (The University of Tokyo, Japan). It was agreed to alternate holding the conference among the above places (China, Japan, Korea, Taiwan, and Hong Kong) once every two years. The next conference has been scheduled to be held at the Southeast University (Nanjing, China) in 2012. The purpose of this series of conferences is to establish a strong collaborative link among the universities of the Asian-Pacific regions and worldwide leading researchers in inverse problems. The conference addressed both theoretical (mathematics), applied (engineering) and developmental aspects of inverse problems. The conference was intended to nurture Asian-American-European collaborations in the evolving interdisciplinary areas and it was envisioned that the conference would lead to long-term commitments and collaborations among the participating countries and researchers. There was a total of more than 100 participants. A call for the submission of papers was sent out after the conference, and a total of 19 papers were finally accepted for publication in this proceedings. The papers included in the proceedings cover a wide scope, which reflects the current flourishing theoretical and numerical research into inverse problems. Finally, as the co-chairs of the Inverse Problems Conference 2010, we wish to express our cordial thanks to all the keynote, plenary, and invited speakers and members of the Advisory Board. We would like to thank the City University of Hong Kong, the Hong Kong Mathematical Society, the K C Wong Education Foundation, the Lee Hysan Foundation, and the Wei Lun Foundation for their generous financial support. Particularly, we wish to thank Miss Lonn Chan for her excellent administrative work in making all the arrangements for the conference. March 2011Yiu-Chung Hon, City University of Hong Kong, HKSARLeevan Ling, Hong Kong Baptist University, HKSAR Invited Keynote SpeakerH Thomas Banks, North Carolina State University, USA Invited Plenary SpeakersRyuichi Ashino, Osaka Kyoiku University, JapanAndrea Caponnetto, City University of Hong Kong, HKSARJeng-Tzong Chen, National Taiwan Ocean University, TaiwanHiromichi Itou, Gunma University, JapanHyeonbae Kang, Inha University, South KoreaMichael Klibanov, University of North Carolina at Charlotte, USAKim Knudsen, Technical University of Denmark, DenmarkRainer Kress, Georg-August-Universität Göttingen, GermanyJérôme Le Rousseau, University of Orleans, FranceChang-Ock Lee, Korea Advanced Institute of Science and Technology (KAIST), South KoreaGui-Rong Liu, University of Cincinnati, USAShuai Lu, Fudan University, ChinaFadil Santosa, University of Minnesota, USATomoya Takeuchi, North Carolina State University, USAXiang Xu, Zhejiang University, ChinaJun Zou, The Chinese University of Hong Kong, HKSAR Invited SpeakersMohamed Abdel-Mooty, The American University in Cairo, EgyptKrishna Agarwal, National University of Singapore, SingaporeHui Cao, Sun Yat-sen University, ChinaWen Chen, Hohai University, ChinaJin Cheng, Fudan University, ChinaLian Duan, University of Oxford, UKMeibao Ge, Zhejiang Sci-Tech University, ChinaRalf Hielscher, TU Chemnitz, GermanyGuanghui Hu, Weierstrass Institute for Applied Analysis and Stochastics (WIAS), GermanyKiwan Jeon, National Institute for Mathematical Sciences, South KoreaYu Jiang, Hokkaido University, JapanDe-Xing Kong, Zhejiang University, ChinaOlga Krivorotko, Novosibirsk State University, RussiaPhilipp Küegler, Austrian Academy of Sciences, AustriaKiwoon Kwon, Dongguk University, South KoreaChun-Kong Law, National Sun Yat-sen University, TaiwanJune-Yub Lee, Ewha Womans University, South KoreaMing Li, City University of Hong Kong, HKSARMikyoung Lim, Korea Advanced Institute of Science and Technology (KAIST), South KoreaJijun Liu, Southeast University, ChinaXiaodong Liu, Chinese Academy of Sciences, ChinaFuming Ma, Jilin University, ChinaHang Ma, Shanghai University, ChinaValdemar Melicher, Ghent University, BelgiumGen Nakamura, Hokkaido University, JapanLong Tuan Nguyen, Ruhr-Universitat Bochum, GermanyEtibar Panakhov, Firat University, TurkeyRobert Plato, University of Siegen, GermanyJean-Pierre Puel, The University of Tokyo, JapanHans-Jürgen Reinhardt, University of Siegen, GermanyMaxim Shishlenin, Sobolev Institute of Mathematics, RussiaIlya Silvestrov, Institute of Petroleum Geology and Geophysics SB RAS, RussiaMourad Sini, Austrian Academy of Sciences, AustriaJán Sládek, Slovak Academy of Sciences, SlovakiaZhijun Tan, Sun Yat-sen University, ChinaQuan-Fang Wang, The Chinese University of Hong Kong, HKSARWenyan Wang, The University of Tokyo, JapanPihua Wen, Queen Mary, University of London, UKZhihai Xiang, Tsinghua University, ChinaXiang-Tuan Xiong, Northwest Normal University, ChinaDinghua Xu, Zhejiang Sci-Tech University, ChinaYongzhi Steve Xu, University of Louisville, USAJiaqing Yang, Chinese Academy of Sciences, ChinaJian Zhang, Sichuan Normal University, ChinaYing Zhang, Fudan University, ChinaTing Zhou, University of Washington, USAJianxin Zhu, Zhejiang University, China Advisory BoardH Thomas Banks, North Carolina State University, USATony F Chan, The Hong Kong University of Science and Technology, HKSARHeinz W Engl, Johannes Kepler Universitát Linz, AustriaRainer Kress, Georg-August-Universitát Góttingen, GermanyTatsien (Daqian) Li, Fudan University, ChinaGunther Uhlmann, University of Washington, USA Organizing CommitteeJin Cheng, Fudan University, ChinaYiu-Chung Hon (Co-Chair), City University of Hong Kong, HKSARJune-Yub Lee, Ewha Womans University, South KoreaLeevan Ling (Co-Chair), Hong Kong Baptist University, HKSARGui-Rong Liu, University of Cincinnati, USAJenn-Nan Wang, National Taiwan University, TaiwanMasahiro Yamamoto, The University of Tokyo, Japan

Q&A with Y.C. Zhang - Bringing Talent and Passion to Power Systems | News

Science.gov Websites

Yingchen Zhang Yingchen Zhang (Y.C.) is the group manager of the sensing and predictive analytics group in appointed manager of the Sensing and Predictive Analytics Group in NREL's Power Systems Engineering Center , my past research involved synchrophasors, which are one type of metering system. Nowadays, many more

Comparative analysis of the gene expression profile of probiotic Lactobacillus casei Zhang with and without fermented milk as a vehicle during transit in a simulated gastrointestinal tract.

PubMed

Wang, Jicheng; Zhong, Zhi; Zhang, Wenyi; Bao, Qiuhua; Wei, Aibin; Meng, He; Zhang, Heping

2012-06-01

Studies have found that the survival of probiotics could be strongly enhanced with dairy products as delivery vehicles, but the molecular mechanism by which this might occur has seldom been mentioned. In this study, microarray technology was used to detect the gene expression profile of Lactobacillus casei Zhang with and without fermented milk used as a delivery vehicle during transit in simulated gastrointestinal juice. Numerous genes of L. casei Zhang in strain suspension were upregulated compared to those from L. casei Zhang in fermented milk. These data might indicate that L. casei Zhang is stimulated directly without the protection of fermented milk, and the high-level gene expression observed here may be a stress response at the transcriptional level. A large proportion of genes involved in translation and cell division were downregulated in the bacteria that were in strain suspension during transit in simulated intestinal juice. This may impede protein biosynthesis and cell division and partially explain the lower viability of L. casei Zhang during transit in the gastrointestinal tract without the delivery vehicle. Copyright © 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Nearshore Wave and Circulation Modelling

DTIC Science & Technology

1998-02-01

1995), "The unified Kadomtsev - Petviashvili equation for interfacial waves," J. Fluid Mech., 288, 383-408. Chen, Y. and Liu, P. L.-F. (1996), "On...modified Kadomtsev - Petviashvili equation for interfacial wave propagation near the critical depth level," Wave Motion (to appear). Cox, D. T. and Kobayashi...94-13. Chen, Y. and Liu, P.L.-F. (1995), "Numerical Study of the Unified Kadomtsev - Petviashvili Equation ," CACR-95-04. Chen, Y. and Liu, P.L.-F

An interview with Margaret A Liu: the future of gene-based vaccines and immunotherapies, and other musings.

PubMed

Liu, Margaret A; Rees, Jenaid

2015-02-01

Interview by Jenaid Rees, commissioning editor. Margaret A Liu is best known for her pioneering work in the area of DNA vaccines. A world renowned scientist, Liu was named one of 'The 50 Most Important Women Scientists' by Discover magazine in 2002. Liu obtained her M.D. from Harvard Medical School, and has held positions at numerous institutions including Harvard Medical School, Massachusetts Institute of Technology, University of Pennsylvania, UCSF, and the Karolinska Institutet in Stockholm. In her career she has served as Senior Advisor in Vaccinology at the Bill & Melinda Gates Foundation and Executive Vice-Chair of the International Vaccine Institute in Seoul, Korea and worked for companies including Merck, Transgène and Chiron Corporation. Her research achievements have led to her receipt of honorary lectureships, and she has held many board positions throughout her career. Liu currently consults in the fields of vaccines and immunotherapy for companies, universities, and non-governmental and governmental scientific organizations, and is a Foreign Adjunct Professor at the Karolinska Institutet in Stockholm, and an Adjunct Professor at the University of California, San Francisco.

In Pursuit of Professionalism in the Field of Chemistry Education in China: The Story of Zhixin Liu

NASA Astrophysics Data System (ADS)

Wei, Bing

2012-09-01

In China, science educators as a professional group were originally referred to as academic staff responsible for teaching the subject-based science teaching methods course at the related science departments at teachers' universities. In this study, a biographic method was used to approach the professional life of Zhixin Liu, who was a senior science educator at the Department of Chemistry at Beijing Normal University, to reveal how he has become a professional science educator and what influences he has brought about to the chemistry education community over the past half a century in China. The main findings of this study were the two roles played by Liu in the enterprise of chemistry education in China: as an agent to disseminate national curriculum policies and as a scholar to construct the Chinese theories of chemistry teaching. Results show that the two roles were intertwined during the whole professional life of Liu. The implications of Liu's life story for dealing with the relationships between policy and practice and between theory and practice in the field of science education are discussed.

The Impact of Nanotechnology Energetics on the Department of Defense by 2035

DTIC Science & Technology

2010-02-17

Kaili Zhang, Daniel Esteve, Pierre Alphonse , Philippe Tailhades and Constantin Vahlas. “Nano-Energetic Materials for MEMS: A Review.” Journal of...on impact and the energetic compounds react. 16 Rossi, Carole, Kaili Zhang, Daniel Esteve, Pierre Alphonse , Philippe Tailhades and Constantin Vahlas...Rossi, Carole, Kaili Zhang, Daniel Esteve, Pierre Alphonse , Philippe Tailhades and Constantin Vahlas. “Nano-Energetic Materials for

Activated type I TGFbeta receptor (Alk5) kinase confers enhancedsurvival to mammary epithelial cells and accelerates mammary tumorprogression

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muraoka-Cook, Rebecca S.; Shin, Incheol; Yi, Jae Youn

2005-01-02

The transforming growth factor-betas (TGF{beta}s) are members of a large superfamily of pleiotropic cytokines that also includes the activins and the bone morphogenetic proteins (BMPs). Members of the TGF{beta} family regulate complex physiological processes such cell proliferation, differentiation, adhesion, cell-cell and cell-matrix interactions, motility, and cell death, among others (Massague, 1998). Dysregulation of TGF{beta} signaling contributes to several pathological processes including cancer, fibrosis, and auto-immune disorders (Massague et al., 2000). The TGF{beta}s elicit their biological effects by binding to type II and type I transmembrane receptor serine-threonine kinases (T{beta}RII and T{beta}RI) which, in turn, phosphorylated Smad 2 and Smad 3.more » Phosphorylated Smad 2/3 associate with Smad 4 and, as a heteromeric complex, translocate to the nucleus where they regulate gene transcription. The inhibitory Smad7 down regulates TGF{beta} signaling by binding to activated T{beta}RI and interfering with its ability to phosphorylate Smad 2/3 (Derynck and Zhang, 2003; Shi and Massague, 2003). Signaling is also regulated by Smad proteolysis. TGF{beta} receptor-mediated activation results in multi-ubiquitination of Smad 2 in the nucleus and subsequent degradation of Smad 2 by the proteasome (Lo and Massague, 1999). Activation of TGF{beta} receptors also induces mobilization of a Smad 7-Smurf complex from the nucleus to the cytoplasm; this complex recognizes the activated receptors and mediates their ubiquitination and internalization via caveolin-rich vesicles, leading to termination of TGF{beta} signaling (Di Guglielmo et al., 2003). Other signal transducers/pathways have been implicated in TGF{beta} actions. These include the extracellular signal-regulated kinase (Erk), c-Jun N-terminal kinase (Jnk), p38 mitogen-activated protein kinase (MAPK), protein phosphatase PP2A, phosphatidylinositol-3 kinase (PI3K), and the family of Rho GTPases [reviewed in (Derynck and Zhang, 2003)]. Although signaling by Smads has been shown to be causally associated with the anti-proliferative effect of TGF{beta} (Datto et al., 1999; Liu et al., 1997), the role of non-Smad effectors on mediating the cellular effects of TGF{beta} is less well characterized.« less

Petrology of metabasic and peridotitic rocks of the Songshugou ophiolite, Qinling orogen, China

NASA Astrophysics Data System (ADS)

Belic, Maximilian; Hauzenberger, Christoph; Dong, Yunpeng

2013-04-01

The Proterozoic Songshugou ophiolite outcrops as a rootless nappe which was emplaced into the southern margin of the Qinling Group. It consists mainly of amphibolite facies metamafic and -ultramafic rocks. Trace element geochemistry and isotope composition show that the mafic rocks are mainly E-MORB and T-MORB metabasalts (Dong et al., 2008b). Within the ophiolite sequence, ultramafic rocks consist mainly of peridotites and serpentinites. Particularly, extremely fresh dunites and harzburgites, are found which do not display a conspicuous metamorphic overprint. The low CaO (<0.39 wt.%) and Al2O3 (<0.51 wt.%) as well as high MgO (41-48 wt.%) contents classify them as depleted non-fertile mantle rocks. Chromite is found as disseminated phase but can sometimes form massive chromite bands. The platinumgroup mineral Laurite (RuS2) could be identified as inclusion in chromites. Usually part of Ru is substituted by Os and Ir. The metamafic rocks consist of garnet, amphibole, symplectitic pyroxenes, ilmenite, apatite, ±zoisite, ±sphene and show a strong metamorphic overprint. Garnet contains numerous inclusions in the core but are nearly inclusion free at the rim. The cores have sometimes snowball textures indicating initially syndeformative growth. Pure albite and prehnite were found in the central parts of the garnets. In the outer portions, pargasitic amphibole, rutile and rarely glaukophane were found. The symplectitic pyroxenes are of diopsidic composition which enclose prehnite and not albite, as common in retrograde eclogitic rocks. Different stages of garnet breakdown to plagioclase and amphibole, from thin plagioclase rims surrounding the garnets to plagioclase rich pseudomorphs, can be observed in different samples. Based on the glaukophane inclusions and symplectitic pyroxenes a high pressure metamorphic event can be concluded. The garnet breakdown to plagioclase and the symplectites clearly indicate a rapid exhumation phase. The age of the metamorphic event is unclear but probably related to the closure of the Shangdan ocean during the early Paleozoic. The financial support by Eurasia-Pacific Uninet is gratefully acknowledged. Dong, Y.P., Zhou, M.F., Zhang, G.W., Zhou, D.W., Liu, L., Zhang, Q., 2008. The Grenvillian Songshugou ophiolite in the Qinling Mountains, Central China: implications for the tectonic evolution of the Qinling orogenic belt. Journal of Asian Earth Science 32 (5-6), 325-335.

The performance of three strawberry varieties on phenological period and quality in Hanyuan County

NASA Astrophysics Data System (ADS)

Che, Meng; Luo, Ya; Ge, Cong; Ling, Yajie; Mo, Qin; Luo, Shu; Tang, Haoru

2018-04-01

In this experiment, `Benihoppe' `Zhang Ji' and `Ning Yu' were used as experimental material, to observe the plant morphology, record the phenological period, investigate the disease situation and determine the quality of strawberry fruit and other indicators and related analysis. Hoping to select a good fruit- type strawberry varieties adapted to the characteristics of Han yuan climate. The result showed that the growth of Benihoppe and Zhang Ji were stronger than Ning Yu, the phenological period of Ning Yu is five days longer than the Benihoppe and Zhang Ji. Ning Yu most highly resistant to the two diseases, followed by Zhang Ji, Benihoppe is the last. In the quality of the fruit, the Benihoppe has the highest average weight and soluble solids. There was no significant difference between Zhang Ji and Ning Yu. However, consumers prefer the Benihoppe, so it is recommended to strengthen the promotion and cultivation of Benihoppe in Han yuan area.

Probing inter- and intrachain Zhang-Rice excitons in Li 2 CuO 2 and determining their binding energy

DOE PAGES

Monney, Claude; Bisogni, Valentina; Zhou, Ke-Jin; ...

2016-10-10

Cuprate materials, such as those hosting high-temperature superconductivity, represent a famous class of materials where the correlations between the strongly entangled charges and spins produce complex phase diagrams. Several years ago, the Zhang-Rice singlet was proposed as a natural quasiparticle in hole-doped cuprates. The occurrence and binding energy of this quasiparticle, consisting of a pair of bound holes with antiparallel spins on the same CuO 4 plaquette, depends on the local electronic interactions, which are fundamental quantities for understanding the physics of the cuprates. Here, we employ state-of-the-art resonant inelastic x-ray scattering (RIXS) to probe the correlated physics of themore » CuO 4 plaquettes in the quasi-one-dimensional chain cuprate Li 2CuO 2. By tuning the incoming photon energy to the O K edge, we populate bound states related to the Zhang-Rice quasiparticles in the RIXS process. Both intra- and interchain Zhang-Rice singlets are observed and their occurrence is shown to depend on the nearest-neighbor spin-spin correlations, which are readily probed in this experiment. Finally, we also extract the binding energy of the Zhang-Rice singlet and identify the Zhang-Rice triplet excitation in the RIXS spectra.« less

Attributing recent changes in droughts over China: 1961-2013

NASA Astrophysics Data System (ADS)

Sun, Fubao; Zhang, Jie; Xu, Jijun; Chen, Yaning; Sang, Yanfang; Liu, Changming

2016-04-01

It is controversial how droughts respond to global warming for the commonly used drought index: the Palmer Drought Severity Index (PDSI). Here we assess recent changes in the droughts over China (1961-2013) using the PDSI with two different estimates, i.e., the Thornthwaite (PDSI_th) and Penman-Monteith (PDSI_pm) approaches. We found that droughts have become more severe in the PDSI_th but slightly lessened in the PDSI_pm estimate. To quantify and attribute that difference in the PDSI_th and PDSI_pm, we designed numerical experiments and found that drying trend of the PDSI_th responding to the global warming alone is 3.4 times higher than that of the PDSI_pm, and the latter was further compensated by decreases in wind speed and solar radiation causing the slightly wetting in the PDSI_pm. Interestingly, we found that inter-basin difference in the PDSI_th and PDSI_pm response to the global warming alone tends to be larger in warmer basins, exponentially depending on mean temperature. References: Zhang, J., F. Sun, J. Xu, Y. Chen, Y. Sang, and C. Liu (2016), Dependence of trends in and sensitivity of drought over China (1961-2013) on potential evaporation model, Geophys. Res. Lett., 43, doi:10.1002/2015GL067473. Sun, F. B., M. L. Roderick, and G. D. Farquhar (2012), Changes in the variability of global land precipitation, Geophys. Res. Lett., 39, L19402, doi: 10.1029/2012GL053369.

Intestinal microbiota contributes to colonic epithelial changes in simulated microgravity mouse model.

PubMed

Shi, Junxiu; Wang, Yifan; He, Jian; Li, Pingping; Jin, Rong; Wang, Ke; Xu, Xi; Hao, Jie; Zhang, Yan; Liu, Hongju; Chen, Xiaoping; Wu, Hounan; Ge, Qing

2017-08-01

Exposure to microgravity leads to alterations in multiple systems, but microgravity-related changes in the gastrointestinal tract and its clinical significance have not been well studied. We used the hindlimb unloading (HU) mouse model to simulate a microgravity condition and investigated the changes in intestinal microbiota and colonic epithelial cells. Compared with ground-based controls (Ctrls), HU affected fecal microbiota composition with a profile that was characterized by the expansion of Firmicutes and decrease of Bacteroidetes. The colon epithelium of HU mice showed decreased goblet cell numbers, reduced epithelial cell turnover, and decreased expression of genes that are involved in defense and inflammatory responses. As a result, increased susceptibility to dextran sulfate sodium-induced epithelial injury was observed in HU mice. Cohousing of Ctrl mice with HU mice resulted in HU-like epithelial changes in Ctrl mice. Transplantation of feces from Ctrl to HU mice alleviated these epithelial changes in HU mice. Results indicate that HU changes intestinal microbiota, which leads to altered colonic epithelial cell homeostasis, impaired barrier function, and increased susceptibility to colitis. We further demonstrate that alteration in gastrointestinal motility may contribute to HU-associated dysbiosis. These animal results emphasize the necessity of evaluating astronauts' intestinal homeostasis during distant space travel.-Shi, J., Wang, Y., He, J., Li, P., Jin, R., Wang, K., Xu, X., Hao, J., Zhang, Y., Liu, H., Chen, X., Wu, H., Ge, Q. Intestinal microbiota contributes to colonic epithelial changes in simulated microgravity mouse model. © FASEB.

Process Reengineering for Quality Improvement in ICU Based on Taylor's Management Theory.

PubMed

Tao, Ziqi

2015-06-01

Using methods including questionnaire-based surveys and control analysis, we analyzed the improvements in the efficiency of ICU rescue, service quality, and patients' satisfaction, in Xuzhou Central Hospital after the implementation of fine management, with an attempt to further introduce the concept of fine management and implement the brand construction. Originating in Taylor's "Theory of Scientific Management" (1982), fine management uses programmed, standardized, digitalized, and informational approaches to ensure each unit of an organization is running with great accuracy, high efficiency, strong coordination, and at sustained duration (Wang et al., Fine Management, 2007). The nature of fine management is a process that breaks up the strategy and goal, and executes it. Strategic planning takes place at every part of the process. Fine management demonstrates that everybody has a role to play in the management process, every area must be examined through the management process, and everything has to be managed (Zhang et al., The Experience of Hospital Nursing Precise Management, 2006). In other words, this kind of management theory demands all people to be involved in the entire process (Liu and Chen, Med Inf, 2007). As public hospital reform is becoming more widespread, it becomes imperative to "build a unified and efficient public hospital management system" and "improve the quality of medical services" (Guidelines on the Pilot Reform of Public Hospitals, 2010). The execution of fine management is of importance in optimizing the medical process, improving medical services and building a prestigious hospital brand.

Measurement of low-frequency magnetic pulses from negative stepped leaders in rocket-triggered lightning flashes

NASA Astrophysics Data System (ADS)

Lu, Gaopeng

2017-04-01

Measurement of low-frequency magnetic pulses from negative stepped leaders in rocket-triggered lightning flashes Gaopeng Lu,1,2 Yanfeng Fan,1,3 Hongbo Zhang,1,3 Rubin Jiang,1,2 Mingyuan Liu,1,2 and Xiushu Qie,1,2 1. Key Laboratory of Middle Atmosphere and Global Environment Observation, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing, 100029, China 2. Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing University of Information Science and Technology, Nanjing, Jiangsu 210044, China 3. University of Chinese Academy of Sciences, Beijing 100049, China We report the measurement of magnetic pulses from the negative stepped leaders in positive rocket-triggered lightning flashes with the low-frequency (4 kHz to 420 kHz) magnetic sensor at two different distances (78 m and 970 m, respectively) during the SHantong Artificial Triggered Lightning Experiments (SHATLE) during summer of 2015. Different from the magnetic radiation from positive leaders as observed in the considerably more frequent cases, the impulsive signals from the negative leader sustain for a much longer time interval, while the attenuation of current pulse launched by the stepping of leader is also observed. The general pattern of magnetic pulses observed for the negative stepped leader is different from the positive counterpart. Also, the initial negative leader appears to be brighter than the positive ones, as shown by both high-speed video observation and the magnetic measurement.

Crystal structure of human esterase D: a potential genetic marker of retinoblastoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Dong; Li, Yang; Song, Gaojie

2009-07-10

Retinoblastoma (RB), a carcinoma of the retina, is caused by mutations in the long arm of chromosome 13, band 13q14. The esterase D (ESD) gene maps at a similar location as the RB gene locus and therefore serves as a potential marker for the prognosis of retinoblastoma. Because very little is known about the structure and function of ESD, we determined the 3-dimensional structure of the enzyme at 1.5 {angstrom} resolution using X-ray crystallography. ESD shows a single domain with an {alpha}/{beta}-hydrolase fold. A number of insertions are observed in the canonical {alpha}/{beta}-hydrolase fold. The active site is located inmore » a positively charged, shallow cleft on the surface lined by a number of aromatic residues. Superimposition studies helped identify the typical catalytic triad residues -- Ser-153, His264, and Asp230 -- involved in catalysis. Mutagenesis of any of the catalytic triad residues to alanine abolished the enzyme activity. Backbone amides of Leu54 and Met150 are involved in the formation of the oxyanion hole. Interestingly, a M150A mutation increased the enzyme activity by 62%. The structure of human ESD determined in this study will aid the elucidation of the physiological role of the enzyme in the human body and will assist in the early diagnosis of retinoblastoma. Wu, D., Li, Y., Song, G., Zhang, D., Shaw, N., Liu, Z. J. Crystal structure of human esterase D: a potential genetic marker of retinoblastoma.« less

Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China.

PubMed

Shuai, Jiang-Bing; Li, Lu-Huan; Li, Ai-Yun; He, Yong-Qiang; Zhang, Xiao-Feng

2017-06-01

Hepatitis E is believed to occur in both endemic and sporadic forms in developing countries, which causes a major public health problem in Asia and Africa (Meng, 2010; Wang et al., 2016a). Recent studies have documented that the disease is also endemic in many industrialized countries (Wenzel et al., 2011). The causative agent, hepatitis E virus (HEV), belonging to the genus Orthohepevirus, is a non-enveloped RNA virus with a single-stranded, positive-sense genome of approximately 7.2 kb (Smith et al., 2014). The genome consists of a short 5' un-translated region (UTR), three open reading frames (ORFs), and a 3' UTR containing a poly(A) tail (Meng, 2011). Four recognized major genotypes of HEV are identified: genotype 1 (Asian and African strains), genotype 2 (a Mexican strain), genotype 3 (primarily from America and Europe, and some Asian countries), and genotype 4 (mainly Asian strains) (Smith et al., 2016). Previous study revealed that HEV genotype 4 is the dominant zoonotic HEV genotype in China (Wang et al., 2016a). However, infections with HEV 3 have been found more commonly in recent years in China (Liu et al., 2012; Zhang et al., 2013). To date, only one full genome of Chinese swine genotype 3 HEV strain from Shanghai has been documented (Si et al., 2009). We report here the first full genome sequence of a genotype 3 swine HEV strain from Zhejiang, China.

A novel polyhedron-based metal-organic framework with high performance for gas uptake and light hydrocarbon separation.

PubMed

Sun, Qiushi; Yao, Shuo; Liu, Bing; Liu, Xinyao; Li, Guanghua; Liu, Xiaoyang; Liu, Yunling

2018-04-03

A novel polyhedron-based metal-organic framework [(CH3)2NH2]2[Zn3(TADIPA)2(DMF)2]·4DMF (JLU-Liu40), which possesses three types of cages with different shapes and sizes, has been successfully synthesized. The framework of JLU-Liu40 is constructed by two inorganic secondary building units (SBUs) of 4-connected square binuclear Zn-paddlewheel and 4-connected tetrahedron mononuclear Zn unit and one organic SBU, which has abundant Lewis basic sites (LBSs), and the framework can be simplified as a pair of 3-connected triangle geometries. Moreover, JLU-Liu40 shows a new (3, 4, 4)-connected topology with the Schläfli symbol {72, 9}2{74, 82}. With the benefit of its high density of open metal sites (OMSs) and LBSs, JLU-Liu40 shows good adsorption ability for some small gases such as N2, CO2, CH4, C2H6 and C3H8. In addition, the theoretical ideal adsorbed solution theory (IAST) calculation indicates that JLU-Liu40 should be a promising material for light gas separation.

Identification of Genes and Proteins Necessary for Catabolism of Acyclic Terpenes and Leucine/Isovalerate in Pseudomonas aeruginosa

PubMed Central

Förster-Fromme, Karin; Höschle, Birgit; Mack, Christina; Bott, Michael; Armbruster, Wolfgang; Jendrossek, Dieter

2006-01-01

Geranyl-coenzyme A (CoA)-carboxylase (GCase; AtuC/AtuF) and methylcrotonyl-CoA-carboxylase (MCase; LiuB/LiuD) are characteristic enzymes of the catabolic pathway of acyclic terpenes (citronellol and geraniol) and of saturated methyl-branched compounds, such as leucine or isovalerate, respectively. Proteins encoded by two gene clusters (atuABCDEFGH and liuRABCDE) of Pseudomonas aeruginosa PAO1 were essential for acyclic terpene utilization (Atu) and for leucine and isovalerate utilization (Liu), respectively, as revealed by phenotype analysis of 10 insertion mutants, two-dimensional gel electrophoresis, determination of GCase and MCase activities, and Western blot analysis of wild-type and mutant strains. Analysis of the genome sequences of other pseudomonads (P. putida KT2440 and P. fluorescens Pf-5) revealed candidate genes for Liu proteins for both species and candidate genes for Atu proteins in P. fluorescens. This result concurred with the finding that P. fluorescens, but not P. putida, could grow on acyclic terpenes (citronellol and citronellate), while both species were able to utilize leucine and isovalerate. A regulatory gene, atuR, was identified upstream of atuABCDEFGH and negatively regulated expression of the atu gene cluster. PMID:16820476

Synthesis, Microstructure and Properties of Metallic Materials with Nanoscale Growth Twins

DTIC Science & Technology

2006-11-01

2004: Wu et al, 2005) and austenitic stainless steels (Zhang et al, 2004a; Zhang et al, 2005). However, processing routes to produce nanoscale...mechanical properties (hardness, yield strength, tensile strength) of bulk austenitic stainless steel (304, 310, 316 and 330) are quite similar and...model developed for the formation of growth twins in sputter- deposited austenitic stainless steel thin films (Zhang et al, 2004b). The model predicts

Introduction to the special issue of "Loess and Climatic Record": Memory of Professor Liu Tungsheng for his scientific contributions and his centenary birthday

NASA Astrophysics Data System (ADS)

Ding, Zhongli; Derbyshire, Edward; Sun, Jimin

2018-04-01

This special issue is to memory Professor Liu Tungsheng for his scientific contributions and his centenary birthday. Liu Tungsheng was the former President of the International Association for Quaternary Association (INQUA), and the Honorary President of the Chinese Association for Quaternary Research (CHIQUA). Liu's best known contribution to Quaternary research is his pioneering and systematic study of the extensive loess deposits of China, which has been regarded as the best terrestrial paleoclimatic archive on the Earth. He won many international awards including the Tyler Prize for Environmental Achievement in 2002 and the Alexander von Humboldt Medal in 2007. He was an inspiring leader, one of China's, and indeed one of the world's most outstanding Earth scientists. This introduction aims to explore the personal factors behind his great achievements and reviews the papers included in this special issue from his colleagues, friends, and students.

Development of Technologies for Early Detection and Stratification of Breast Cancer

DTIC Science & Technology

2016-12-01

heterogeneous nature of these cells. Figure 17 shows a yellow emitting Pdot (semiconducting polymer dot), which is a new family of ultra-bright fluorescent...Yu, J., Zhang, X., Sun, W., Ye, F., Wu, I., Zhang, Y., Hayden, S., Zhang, Y., Wu, C., Chiu, D.T. "New yellow fluorescent semiconducting polymer dots...fluorescent fluorinated semiconducting polymer dots for cellular imaging and analysis" Chemical Communication, 2013, 49, 8256-8258. • Zhao, M., Wei, B

BATTLE (Biomarker-based Approach of Targeted Therapy for Lung Cancer Elimination)

DTIC Science & Technology

2012-04-01

Wistuba,Ignacio Ivan Woods ,Denise M Wu,Huakang Xue,Yuwen Yang,Bijun Yin,Ming Zhang,Guangcheng Zhang,Li Army...Oncol. 2009; 27: 271–8. 127 Ishii Y, Rex M, Scotting PJ et al. Region-specific expression of chicken Sox2 in the developing gut and lung epithelium... Wood ER, Shewchuk L, Hassel A, et al. Discovery of an in- hibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency

Studies on idiocerine leafhoppers with descriptions of Chinaocerus gen. nov. and three new species from China (Hemiptera: Cicadomorpha: Cicadellidae).

PubMed

Dang, Li-Hong; Zhang, Bin; Li, Zi-Zhong

2016-03-08

A new leafhopper genus of the tribe Idiocerini (Hemiptera: Cicadomorpha: Cicadellidae), Chinaocerus, is described from the southwest China together with three new species, C. kangdingensis Zhang & Li sp. nov. (Sichuan Province), C. bispinatus Zhang & Li sp. nov. (Yunnan Province) and C. shii Zhang & Li sp. nov. (Sichuan Province). Descriptions and illustrations of these three new species are provided, and a key for their separation is also given.

Multi-sensor data processing method for improved satellite retrievals

NASA Astrophysics Data System (ADS)

Fan, Xingwang

2017-04-01

Satellite remote sensing has provided massive data that improve the overall accuracy and extend the time series of environmental studies. In reflective solar bands, satellite data are related to land surface properties via radiative transfer (RT) equations. These equations generally include sensor-related (calibration coefficients), atmosphere-related (aerosol optical thickness) and surface-related (surface reflectance) parameters. It is an ill-posed problem to solve three parameters with only one RT equation. Even if there are two RT equations (dual-sensor data), the problem is still unsolvable. However, a robust solution can be obtained when any two parameters are known. If surface and atmosphere are known, sensor intercalibration can be performed. For example, the Advanced Very High Resolution Radiometer (AVHRR) was calibrated to the MODerate-resolution Imaging Spectroradiometer (MODIS) in Fan and Liu (2014) [Fan, X., and Liu, Y. (2014). Quantifying the relationship between intersensor images in solar reflective bands: Implications for intercalibration. IEEE Transactions on Geoscience and Remote Sensing, 52(12), 7727-7737.]. If sensor and surface are known, atmospheric data can be retrieved. For example, aerosol data were retrieved using tandem TERRA and AQUA MODIS images in Fan and Liu (2016a) [Fan, X., and Liu, Y. (2016a). Exploiting TERRA-AQUA MODIS relationship in the reflective solar bands for aerosol retrieval. Remote Sensing, 8(12), 996.]. If sensor and atmosphere are known, data consistency can be obtained. For example, Normalized Difference Vegetation Index (NDVI) data were intercalibrated among coarse-resolution sensors in Fan and Liu (2016b) [Fan, X., and Liu, Y. (2016b). A global study of NDVI difference among moderate-resolution satellite sensors. ISPRS Journal of Photogrammetry and Remote Sensing, 121, 177-191.], and among fine-resolution sensors in Fan and Liu (2017) [Fan, X., and Liu, Y. (2017). A generalized model for intersensor NDVI calibration and its comparison with regression approaches. IEEE Transactions on Geoscience and Remote Sensing, 55(3), doi: 10.1109/TGRS.2016.2635802.]. These studies demonstrate the success of multi-sensor data and novel methods in the research domain of geoscience. These data will benefit remote sensing of terrestrial parameters in decadal timescales, such as soil salinity content in Fan et al. (2016) [Fan, X., Weng, Y., and Tao, J. (2016). Towards decadal soil salinity mapping using Landsat time series data. International Journal of Applied Earth Observation and Geoinformation, 52, 32-41.].

Effect of acute pancreatitis on the pharmacokinetics of Chinese herbal ointment Liu-He-Dan in anaesthetized rats.

PubMed

Zhao, Xian-Lin; Xiang, Jin; Wan, Mei-Hua; Yu, Qin; Chen, Wei-wei; Chen, Guang-Yuan; Tang, Wen-Fu

2013-01-09

Chinese herbal preparation of Liu-He-Dan ointment has been adapted for acute pancreatitis in external application for many years in West China. To investigate the effect of acute pancreatitis on the pharmacokinetics of Liu-He-Dan ointment in rats while it was used externally on belly. Twelve male Sprague-Dawley rats were randomly divided into acute pancreatitis model group (n=6) and normal group as a control (n=6). Chinese herbal Liu-He-Dan ointment was used externally on belly. Emodin, rhein, aloe emodin, physcion and chrysophanol in plasma and pancreas (at 48 h) were detected and quantified by liquid chromatography-tandem mass spectrometry. Amylase in plasma were determined with iodide process. Among the five components, only emodin, aloe emodin and physcion from Liu-He-Dan were detected in plasma and pancreas. The absorption of each component was tended to decrease in acute pancreatitis group after topically management with Liu-He-Dan ointment on rats' abdomen. The T(max), C(max) and area under curve (AUC) of each component were distinctly lower in AP group than those in normal group (p<0.05). However, the T(1/2α) and mean retention time (MRT) of emodin lasted longer in acute pancreatitis group than those in normal group (p<0.05). There was no statistical difference in the MRT of aloe emodin and physcion between the two groups. Emodin could be detected in all rats' pancreas at 48 h in both groups, while its mean pancreatic concentration was higher in acute pancreatitis model group than in normal group (0.91 ± 0.68, 0.41 ± 0.36, respectively). Physcion could be detected in pancreas of most acute pancreatitis models, but not in normal rats. Aloe emodin was found in all pancreas from acute pancreatitis models while only one in normal group. The level of amylase in Liu-He-Dan group was obviously lower than that in the AP model group (p=0.0055). We concluded that acute pancreatitis may significantly affect the pharmacokinetics of Liu-He-Dan while external applied on belly, which indicated the dosage modification in AP. However, acute pancreatitis seems to promote the distribution of the detected components into pancreas. The ointment could help relieve the disease of pancreatitis. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Development of Magnetic Resonance Imaging Biomarkers for Traumatic Brain Injury

DTIC Science & Technology

2014-09-01

beta4 improves functional neurological outcome in a rat model of embolic stroke. Neuroscience 169:674–682. Morris DC, Zhang ZG, Zhang J, Xiong Y, Zhang...score of 15 with abrasion and a small laceration on his left eyebrow without closure and left clavicle fracture . His major clinical symptoms were left...Issue 11 | e80296 patient was a victim of an assault and suffered brief loss of consciousness and femur fracture . He presented in the ED with a GCS

Solar Energy Enhancement Using Down-converting Particles: A Rigorous Approach

DTIC Science & Technology

2011-06-06

Solar energy enhancement using down-converting particles: A rigorous approach Ze’ev R. Abrams,1,2 Avi Niv ,2 and Xiang Zhang2,3,a) 1Applied Science...System 1. 114905-2 Abrams, Niv , and Zhang J. Appl. Phys. 109, 114905 (2011) [This article is copyrighted as indicated in the article. Reuse of AIP...This increase per band-gap is displayed in 114905-3 Abrams, Niv , and Zhang J. Appl. Phys. 109, 114905 (2011) [This article is copyrighted as indicated

Mechanisms of Residual Stress Generation in Mechanical Surface Treatment: the Role of Cyclic Plasticity and Texture

DTIC Science & Technology

2015-08-24

modulus, yield strength, strain hardening exponent, and hardness can be estimated by this technique (Pethica 1982, Newey, Wilkins & Pollock 1982, Stone et...properties of metal alloys: a review", International Journal of Fatigue, vol. 24, no. 10, pp. 1021-1036. Newey, D., Wilkins , M.A. & Pollock, H.M. 1982...Zhang, Y., Zhang, S., Yu, C., Tang , Y., Zhang, H., Wu, H., Guo, D., Wang, S., Xia, X., Chen, M. & Dai, Y. 1997, "Laser shock-processing for

Androgen Receptor Splice Variants and Resistance to Taxane Chemotherapy

DTIC Science & Technology

2017-10-01

presence or absence of androgen. Citations (published journal articles): Xichun Liu, Elisa Ledet, Dongying Li, Ary Dotiwala, Allie Steinberger...paper was published: Xichun Liu, Elisa Ledet, Dongying Li, Ary Dotiwala, Allie Steinberger, Jianzhuo Li, Yanfeng Qi, Yan Dong, Jonathan Silberstein

Identification of Measures Related to Cross-Cultural Competence

DTIC Science & Technology

2008-01-01

510. Miville, M. L., Gelso, C. J., Liu, W., Pannu , R., Touradji, P., Holloway, P., & Fuertes, J. (1999). Appreciating similarities and valuing...GUDS. Miville, Holloway, Gelso, Pannu , Liu, Touradji, & Fuertes (1999) Vontress (1996) proposed that people are the products of several

EDITORIAL: Global impacts of particulate matter air pollution

NASA Astrophysics Data System (ADS)

Bell, Michelle L.; Holloway, Tracey

2007-10-01

Even in well-studied, data-rich regions of the United States and Europe, understanding ambient particulate matter (PM, aka aerosols) remains a challenge. Atmospheric aerosols exhibit chemical heterogeneity, spatial and seasonal variability, and result in a wide range of health impacts (mortality, respiratory disease, cardiovascular disease, eye irritation, and others). In addition, aerosols play an important role in climate, exerting warming effects (black carbon), cooling effects (sulfate and organic carbon), and affecting precipitation and cloud cover. Characterizing the emission sources, concentrations, transport patterns, and impacts is particularly difficult in developing countries, where data are scarce, emissions are high, and health impacts are often severe. We are pleased to present this focus issue of Environmental Research Letters (ERL) devoted to the study of PM on an international scale. Our authors are leading researchers who each bring cross-cutting analysis to this critical health and environmental issue. Collectively, the research presented here contributes to our understanding of PM sources, processes, and impacts, while highlighting key steps forward. In this issue, Zhang et al examine the size distribution and composition of emitted anthropogenic PM in China, finding that the characteristics of primary aerosol emissions differ significantly between industrialized and developing regions in China. Concentration measurements of PM, like detailed emissions inventories, are rare in the developing world. van Vliet and Kinney analyze fine particles in Nairobi based on monitoring data for PM2.5 and black carbon. Using measurements from multiple locations of differing proximity to roadways, the authors evaluate traffic-source contributions to PM exposure. The impact of emission location and exposed population are also evaluated by Liu and Mauzerall, but on a continent-to-continent scale. The authors quantify the connection between SO2 emissions and sulfate aerosol exposure (both domestically and on downwind continents), while presenting a new metric to quantify the impact of distance on health-relevant exposure: the 'influence potential'. Extending the scope of aerosol impacts from health to climate, Bond outlines the barriers to including aerosols in climate agreements, and proposes solutions to facilitate the integration of this key climate species in a policy context. Together, the articles scope out the state-of-the-science with respect to key issues in international air pollution. All four studies advance understanding the human health implications of air pollution, by drawing from worldwide data sources and considering a global perspective on key processes and impacts. To extend exposure estimates, like those of van Vliet and Kinney or Liu and Mauzerall, and to evaluate the induced physiological response of PM exposure, typically existing dose response relationships are applied. Unfortunately, the common practice of applying health response estimates from one location to another is problematic. In addition to potential differences in the chemical composition of particles, the underlying populations may differ with respect to their baseline health status, occupational exposures, age and gender distribution, and behavioral factors such as nutrition and smoking habits. Health response to a given stressor is affected by the quality of and access to health care, which varies widely, and can be almost non-existent in some regions of developing countries. Further, exposure to ambient PM is affected by the relative fraction of time spent in different settings (e.g., work, home, outside, in transit), the activities that affect ventilation rate (e.g., exercising heavily versus sitting still), and housing characteristics that alter the penetration of outdoor particles into indoor environments (e.g., housing materials, windows, air conditioning). To make the most of exposure estimates, the 'missing link' is the development of dose response relationships that take into account how the high degree of source and demographic variability affect PM health response. We look forward to the continued growth of research in ERL contributing to air pollution emissions, distribution, and impacts. As the integrated study of air quality connects to economics, energy, agriculture, meteorology, climate change, and public health—among other subjects—its advancement is well-suited to an interdisciplinary, open-access journal like ERL. Thanks to our authors for contributing to ERL's growth in global air pollution research with such excellent work. Focus on Global Impacts of Particulate Matter Air Pollution Contents The articles below represent the first accepted contributions and further additions will appear in the near future. Major components of China's anthropogenic primary particulate emissions Qiang Zhang, David G Streets, Kebin He and Zbigniew Klimont Impacts of roadway emissions on urban particulate matter concentrations in sub-Saharan Africa: new evidence from Nairobi, Kenya E D S van Vliet and P L Kinney Potential influence of inter-continental transport of sulfate aerosols on air quality Junfeng Liu and Denise L Mauzerall Can warming particles enter global climate discussions? Tami C Bond

Taxonomic study of the cricket genus Valiatrella Gorochov (Gryllidae, Podoscirtinae) from China.

PubMed

Libin, Ma; Yalin, Zhang

2013-01-01

Four Valiatrella species, Valiatrella pulchra (Gorochov, 1985), Valiatrella sororia (Gorochov, 2002), Valiatrella laminaria Liu & Shi, 2007 and Valiatrella multiprotubera Liu & Shi, 2007, recorded from China are reviewed. A new species, Valiatrella persicifolius sp. nov., is described and illustrated.

Genetics Home Reference: familial hemophagocytic lymphohistiocytosis

MedlinePlus

... Marsh RA, Satake N, Biroschak J, Jacobs T, Johnson J, Jordan MB, Bleesing JJ, Filipovich AH, Zhang ... 14. Citation on PubMed Zhang K, Filipovich AH, Johnson J, Marsh RA, Villanueva J. Hemophagocytic Lymphohistiocytosis, Familial. ...

EDITORIAL: Focus on Cloaking and Transformation Optics

NASA Astrophysics Data System (ADS)

Leonhardt, Ulf; Smith, David R.

2008-11-01

'Any sufficiently advanced technology is indistinguishable from magic', as the late Arthur C Clarke wrote. So what does it take to do magic by technology? Transformation optics has developed some tantalizing ideas and the first practical demonstrations of 'pure and applied magic'. Transformation optics gathers an unusual mix of scientists, ranging from practically-minded engineers to imaginative theoretical physicists and mathematicians or hybrids of all three. The engineers have been developing new materials with extraordinary electromagnetic properties, from materials for microwaves, to be used in radar or wireless technology, to materials for terahertz radiation and visible light. These materials typically are composites—they consist of artificial structures much smaller than the wavelength that act like man-made atoms, apart being much larger in size. The properties of these artificial atoms depend on their shapes and sizes and so they are tunable, in contrast to most real atoms or molecules. This degree of control is what makes these materials—called metamaterials—so interesting. Such new-won freedom invites the other side of the spectrum of scientists, the theorists, to dream. Just imagine there are no practical limits on electromagnetic materials—what could we do with them? One exciting application of metamaterials has been Veselago's idea of negative refraction, dating back to the 1960s. Metamaterials have breathed life into Veselago's idea, culminating in recent optical demonstrations (see for example [1,2]). Another application is cloaking, developing ideas and first experimental demonstrations for invisibility devices [3]. It turns out that both negative refraction and cloaking are examples where materials seem to transform the geometry of space. Any optical material appears to change light's perception of space, as countless optical illusions prove, but the materials of transformation optics act in more specific ways: they appear to perform coordinate transformations. If the coordinates they conjure up run backwards one gets negative refraction, if they exclude some region of space one makes anything inside invisible [4]. In physics, general relativity has honed the theoretical tools for understanding curved space and curved-coordinate transformations. In transformation optics, general relativity has become a theoretical tool for solving practical engineering problems [4]. What an unorthodox connection! This focus issue represents a snapshot of this rapidly developing research area. It is not restricted to optics or electromagnetism, though. Metamaterials for acoustics also exist and can be applied in ways similar to optical metamaterials. So transformation optics not only attracts an unusual mix of scientists, but also spans a range of applications in optics and beyond. Transformation optics has the potential to transform optics, for example by visualizing invisibility and making materials beyond materials—metamaterials. But before we transgress the boundaries to the hermeneutics of transformation optics [5], let the papers speak for themselves. References [1] Yao J, Liu Z, Liu Y, Wang Y, Sun C, Bartal G, Stacy A M and Zhang X 2008 Science 321 930 [2] Valentine J, Zhang S, Zentgraf T, Ulin-Avila E, Genov D A, Bartal G and Zhang X 2008 Nature 455 376 [3] Schurig D, Mock J J, Justice B J, Cummer S A, Pendry J B, Starr A F and Smith D R 2006 Science 314 977 [4] Leonhardt U and Philbin T G 2006 New J. Phys. 8 247 [5] Sokal A D 1996 Social Text 14(46/47) 217 Focus on Cloaking and Transformation Optics Contents Transformation optics for the full dielectric electromagnetic cloak and metal-dielectric planar hyperlens D P Gaillot, C Croënne, F Zhang and D Lippens Transmutation of singularities in optical instruments Tomáš Tyc and Ulf Leonhardt Electromagnetic cloaking with canonical spiral inclusions K Guven, E Saenz, R Gonzalo, E Ozbay and S Tretyakov Theory and potentials of multi-layered plasmonic covers for multi-frequency cloaking Andrea Alù and Nader Engheta Electromagnetic cloaking devices for TE and TM polarizations Filiberto Bilotti, Simone Tricarico and Lucio Vegni An aberration-free lens with zero F-number D Schurig Transformational optics of plasmonic metamaterials I I Smolyaninov An acoustic metafluid: realizing a broadband acoustic cloak J B Pendry and Jensen Li On the possibility of metamaterial properties in spin plasmas G Brodin and M Marklund A homogenization route towards square cylindrical acoustic cloaks Mohamed Farhat, Sébastien Guenneau, Stefan Enoch, Alexander Movchan, Frédéric Zolla and André Nicolet Transformation optics: approaching broadband electromagnetic cloaking A V Kildishev, W Cai, U K Chettiar and V M Shalaev Generalized field-transforming metamaterials Sergei A Tretyakov, Igor S Nefedov and Pekka Alitalo Electromagnetic beam modulation through transformation optical structures Xiaofei Xu, Yijun Feng and Tian Jiang Superantenna made of transformation media Ulf Leonhardt and Tomáš Tyc Material parameters and vector scaling in transformation acoustics Steven A Cummer, Marco Rahm and David Schurig Isotropic transformation optics: approximate acoustic and quantum cloaking Allan Greenleaf, Yaroslav Kurylev, Matti Lassas and Gunther Uhlmann Transformation optical designs for wave collimators, flat lenses and right-angle bends Do-Hoon Kwon and Douglas H Werner Alternative derivation of electromagnetic cloaks and concentrators A D Yaghjian and S Maci Solutions in folded geometries, and associated cloaking due to anomalous resonance Graeme W Milton, Nicolae-Alexandru P Nicorovici, Ross C McPhedran, Kirill Cherednichenko and Zubin Jacob Finite wavelength cloaking by plasmonic resonance N-A P Nicorovici, R C McPhedran, S Enoch and G Tayeb

PREFACE: Dynamic crossover phenomena in water and other glass-forming liquids Dynamic crossover phenomena in water and other glass-forming liquids

NASA Astrophysics Data System (ADS)

Chen, Sow-Hsin; Baglioni, Piero

2012-02-01

This special section has been inspired by the workshop on Dynamic Crossover Phenomena in Water and Other Glass-Forming Liquids, held during November 11-13, 2010 at Pensione Bencistà, Fiesole, Italy, a well-preserved 14th century Italian villa tucked high in the hills overlooking Florence. The meeting, an assembly of world renowned scientists, was organized as a special occasion to celebrate the 75th birthday of Professor Sow-Hsin Chen of MIT, a pioneer in several aspects of complex fluids and soft matter physics. The workshop covered a large variety of experimental and theoretical research topics of current interest related to dynamic crossover phenomena in water and, more generally, in other glass-forming liquids. The 30 invited speakers/lecturers and approximately 60 participants were a select group of prominent physicists and chemists from the USA, Europe, Asia and Mexico, who are actively working in the field. Some highlights of this special issue include the following works. Professor Yamaguchi's group and their collaborators present a neutron spin echo study of the coherent intermediate scattering function of heavy water confined in cylindrical pores of MCM-41-C10 silica material in the temperature range 190-298 K. They clearly show that a fragile-to-strong (FTS) dynamic crossover occurs at about 225 K. They attribute the FTS dynamic crossover to the formation of a tetrahedral-like structure, which is preserved in the bulk-like water confined to the central part of the cylindrical pores. Mamontov and Kolesnikov et al study the collective excitations in an aqueous solution of lithium chloride over a temperature range of 205-270 K using neutron and x-ray Rayleigh-Brillouin (coherent) scattering. They detect both the low-frequency and the high-frequency sounds known to exist in pure bulk water above the melting temperature. They also perform neutron (incoherent) and x-ray (coherent) elastic intensity scan measurements. Clear evidence of the crossover in the dynamics of the water molecules in the solution is observed in the single-particle relaxational dynamics in the μeV (nanosecond) time scale, but not in the collective dynamics on the meV (picosecond) time scale. Mallamace et al discuss the dynamic crossover phenomenon in both bulk water and protein hydration water. They collect previous and new experimental data from different experimental techniques and molecular dynamic simulations, and are able to develop a unified picture for the different dynamical findings. Gallo et al present a MD study of confined water in MCM-41S-15 in order to test the applicability of Mode Coupling Theory (MCT) to the dynamics of the hydration water confined in the cylindrical pores of nominal diameter 15 Å. They find that the self dynamics of the hydration water is well described by MCT down to the crossover temperature TC. However, below TC the predictions of idealized MCT no longer apply, since hopping processes intervene and water turns into a strong liquid. Soper raises some questions as to the validity of the analysis method employed to determine the density of water confined in porous silica material MCM-41-S15 from recent neutron scattering experiments. Professors Stanley, Franzese and his collaborators describe an efficient Monte Carlo simulation of a coarse-grained model of water to study the phase diagram of a water monolayer confined in a fixed disordered matrix of hydrophobic nanoparticles between two hydrophobic plates. They find a drastic change of phase behavior of the confined water, such as shortening of the liquid-liquid phase transition line, upon increasing the concentration of the hydrophobic nano-particles. Sciortino and collaborators compute the equilibrium phase diagram of two simple models for patchy particles with three and five patches in a very broad range of pressure and temperature. The three-patch model produces a stable gas-liquid critical point. Yun Liu et al investigate, via small angle neutron scattering and neutron spin echo measurements, the effect of temperature on dynamic cluster formation of concentrated lysozyme solutions. Xin Li et al explore the use of the newly developed technique of spin echo small angle neutron scattering (SESANS) to investigate the structure of a colloid. They find the SESANS is able to resolve structural heterogeneity, at both intra- and inter-colloidal length scales. The choice of the topics and their elaboration reflects both the diversified current and past research interests of Professor Chen to whom this special section of Journal of Physics: Condensed Matter is dedicated. The issue contains papers from a substantial number of the invited speakers. The papers are arranged in the three categories of water, other glass-forming liquids, and colloids. It is our pleasure to thank all speakers, section chairs and participants who contributed to the great success of the workshop, and to all authors for their additional efforts in preparing their manuscripts. The scientific program of the workshop was organized by Professor Sow-Hsin Chen and Professor Piero Baglioni. The meeting was only possible with the generous financial support of the Consorzio per lo Sviluppo dei Sistemi a Grande Interfase (CSGI) and the University of Florence, Italy. Finally, we express our warmest gratitude to all the members of the local organizing committee and to the staff of the CSGI for all their assistance and great efforts in organizing this meeting. Dynamic crossover phenomena in water and other glass-forming liquids contents Water Neutron spin echo measurements of monolayer and capillary condensed water in MCM-41 at low temperaturesK Yoshida, T Yamaguchi, S Kittaka, M-C Bellissent-Funel and P Fouquet Water dynamics in a lithium chloride aqueous solution probed by Brillouin neutron and x-ray scatteringE Mamontov, A De Francesco, F Formisano, A Laloni, L Sani, B M Leu, A H Said and A I Kolesnikov The dynamical crossover phenomenon in bulk water, confined water and protein hydration water Francesco Mallamace, Carmelo Corsaro, Piero Baglioni, Emiliano Fratini and Sow-Hsin Chen Common features in the microscopic dynamics of hydration water on organic and inorganic surfacesE Mamontov, H O'Neill, Q Zhang, W Wang and D J Wesolowski Water dynamics as affected by interaction with biomolecules and change of thermodynamic state: a neutron scattering studyA Orecchini, A Paciaroni, C Petrillo, F Sebastiani, A De Francesco and F Sacchetti Temperature dependence of structure and density for D2O confined in MCM-41-SWilliam A Kamitakahara, Antonio Faraone, Kao-Hsiang Liu and Chung-Yuan Mou Density profile of water confined in cylindrical pores in MCM-41 silicaAlan K Soper Dynamic crossover in hydration water of curing cement paste: the effect of superplasticizerHua Li, Wei-Shan Chiang, Emiliano Fratini, Francesca Ridi, Francesco Bausi, Piero Baglioni, Madhu Tyagi and Sow-Hsin Chen Water confined in MCM-41: a mode coupling theory analysisP Gallo, M Rovere and S-H Chen Computer simulations of dynamic crossover phenomena in nanoconfined waterG B Suffritti, P Demontis, J Gulín-Gonźlez and M Masia Hydrophobic nanoconfinement suppresses fluctuations in supercooled waterE G Strekalova, M G Mazza, H E Stanley and G Franzese Other glass-forming liquids Quasi-elastic neutron scattering studies of the slow dynamics of supercooled and glassy aspirinYang Zhang, Madhusudan Tyagi, Eugene Mamontov and Sow-Hsin Chen Colloids Phase diagram of trivalent and pentavalent patchy particlesFlavio Romano, Eduardo Sanz, Piero Tartaglia and Francesco Sciortino Distinguishing the monomer to cluster phase transition in concentrated lysozyme solutions by studying the temperature dependence of the short-time dynamicsPéter Falus, Lionel Porcar, Emiliano Fratini, Wei-Ren Chen, Antonio Faraone, Kunlun Hong, Piero Baglioni and Yun Liu Contrast variation in spin-echo small angle neutron scatteringXin Li, Bin Wu, Yun Liu, Roger Pynn, Chwen-Yang Shew, Gregory S Smith, Kenneth W Herwig, J Lee Robertson, Wei-Ren Chen and Li Liu Structural response of polyelectrolyte dendrimer towards molecular protonation: the inconsistency revealed by SANS and NMRKunlun Hong, Yun Liu, Lionel Porcar, Dazhi Liu, Carrie Y Gao, Gregory S Smith, Kenneth W Herwig, Sheng Cai, Xin Li, Bin Wu, Wei-Ren Chen and Li Liu

DOE Office of Scientific and Technical Information (OSTI.GOV)

Monney, Claude; Bisogni, Valentina; Zhou, Ke-Jin

Cuprate materials, such as those hosting high-temperature superconductivity, represent a famous class of materials where the correlations between the strongly entangled charges and spins produce complex phase diagrams. Several years ago, the Zhang-Rice singlet was proposed as a natural quasiparticle in hole-doped cuprates. The occurrence and binding energy of this quasiparticle, consisting of a pair of bound holes with antiparallel spins on the same CuO 4 plaquette, depends on the local electronic interactions, which are fundamental quantities for understanding the physics of the cuprates. Here, we employ state-of-the-art resonant inelastic x-ray scattering (RIXS) to probe the correlated physics of themore » CuO 4 plaquettes in the quasi-one-dimensional chain cuprate Li 2CuO 2. By tuning the incoming photon energy to the O K edge, we populate bound states related to the Zhang-Rice quasiparticles in the RIXS process. Both intra- and interchain Zhang-Rice singlets are observed and their occurrence is shown to depend on the nearest-neighbor spin-spin correlations, which are readily probed in this experiment. Finally, we also extract the binding energy of the Zhang-Rice singlet and identify the Zhang-Rice triplet excitation in the RIXS spectra.« less

New Hires at the National Cancer Institute at Frederick | Poster

Cancer.gov

Fifty-one people joined the facility in November and December 2013. The National Cancer Institute welcomes… Emily Boward Emad Darvishi Shuo Gu Sanath Kumar Janaka Robert Kortum Yasmin Lachir Jinbian Liu Yang Liu Eric Ramirez Salazar Brett Shelley Li Xia Jaeho Yoon

Ballistic Phosphorene Transistor

DTIC Science & Technology

2015-11-19

IEEE Electron Devices Letters 35 (7): 795-797, 2014. 2. Yexin Deng, Zhe Luo, Nathan J. Conrad, Han Liu, Yongji Gong, Sina Najmaei, Pulickel M...IEEE Electron Devices Letters 35 (7): 795-797, 2014. 2. Yexin Deng, Zhe Luo, Nathan J. Conrad, Han Liu, Yongji Gong, Sina Najmaei, Pulickel M

Liu Tungsheng: A geologist from a traditional Chinese cultural background who became an international star of science

NASA Astrophysics Data System (ADS)

Zhang, Yuhong; Guan, Li; Liu, Qiang

2018-04-01

Liu Tungsheng (1917-2008) resumed his scientific career and became actively involved on the international stage in the field of Quaternary Sciences after 1982, at the age of 65, following Deng Xiaoping's 'Reform and Open Up' policy, after his first international publication of China loess research published in 1950s. Though his best known contribution to Quaternary research is his pioneering study of the extensive loess deposits of China, several other important scientific contributions are less widely known, as they were published in Chinese. By studying about 400 well-preserved fieldwork notebooks left by Liu Tungsheng, as well as many biographical and personal photographic collections, we have mapped his remarkable life during his 91-year journey and the contributions to geoscience. From a historical point of view, Liu Tungsheng created a unique chapter in the history of modern geological science in China in his role as a geologist emerging from a traditional Chinese cultural background who became a star on the international scientific stage.

Characterization of Ignition and Combustion Properties of Nanowire-based Energetics

DTIC Science & Technology

2013-07-23

Sannia, A. Cincotti, G. Cao, Chem. Eng. Sci. 54 (15–16) (1999) 3053–3061. [4] C. Rossi, K. Zhang, D. Esteve, P. Alphonse , P. Tailhades, C. Vahlas, J...94 (5) (2003) 2923–2929. [30] K. Zhang, C. Rossi, G.A.A. Rodriguez, C. Tenail- leau, P. Alphonse , Appl. Phys. Lett. 91 (11) (2007) 113117/1–113117/3...Pister, Smart Mater. Struct. 10(6), 1145 (2001). 8C. Rossi, K. Zhang, D. Esteve, P. Alphonse , P. Tailhades, and C. Vahlas, J. Microelectromech. Syst. 16

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Juhui; School of Computatioal Sciences, Korea Institute for Advanced Study, Seoul 130-722; Lee, Soojoon

Extending the eavesdropping strategy devised by Zhang, Li, and Guo [Zhang, Li, and Guo, Phys. Rev. A 63, 036301 (2001)], we show that the multiparty quantum communication protocol based on entanglement swapping, which was proposed by Cabello (e-print quant-ph/0009025), is not secure. We modify the protocol so that entanglement swapping can secure multiparty quantum communication, such as multiparty quantum key distribution and quantum secret sharing of classical information, and show that the modified protocol is secure against the Zhang-Li-Guo strategy for eavesdropping as well as the basic intercept-resend attack.0.

Calculated momentum dependence of Zhang-Rice states in transition metal oxides.

PubMed

Yin, Quan; Gordienko, Alexey; Wan, Xiangang; Savrasov, Sergey Y

2008-02-15

Using a combination of local density functional theory and cluster exact diagonalization based dynamical mean field theory, we calculate many-body electronic structures of several Mott insulating oxides including undoped high T(c) materials. The dispersions of the lowest occupied electronic states are associated with the Zhang-Rice singlets in cuprates and with doublets, triplets, quadruplets, and quintets in more general cases. Our results agree with angle resolved photoemission experiments including the decrease of the spectral weight of the Zhang-Rice band as it approaches k=0.

Compression and Associated Properties of Boron Carbide

DTIC Science & Technology

2008-12-01

of Brookhaven National Laboratory ( BNL ) with the light extracted from the x-ray source in a method previously described (Liu et al., 2002).. A...are sharper and more intense relative to as received material. ACKNOWLEDGMENTS Thanks are due to Dr. Jingzhu Hu and Dr. Zhenxian Liu of BNL

A new security solution to JPEG using hyper-chaotic system and modified zigzag scan coding

NASA Astrophysics Data System (ADS)

Ji, Xiao-yong; Bai, Sen; Guo, Yu; Guo, Hui

2015-05-01

Though JPEG is an excellent compression standard of images, it does not provide any security performance. Thus, a security solution to JPEG was proposed in Zhang et al. (2014). But there are some flaws in Zhang's scheme and in this paper we propose a new scheme based on discrete hyper-chaotic system and modified zigzag scan coding. By shuffling the identifiers of zigzag scan encoded sequence with hyper-chaotic sequence and accurately encrypting the certain coefficients which have little relationship with the correlation of the plain image in zigzag scan encoded domain, we achieve high compression performance and robust security simultaneously. Meanwhile we present and analyze the flaws in Zhang's scheme through theoretical analysis and experimental verification, and give the comparisons between our scheme and Zhang's. Simulation results verify that our method has better performance in security and efficiency.

Direct Observation of Zhang-Li Torque Expansion of Magnetic Droplet Solitons

NASA Astrophysics Data System (ADS)

Chung, Sunjae; Le, Q. Tuan; Ahlberg, Martina; Awad, Ahmad A.; Weigand, Markus; Bykova, Iuliia; Khymyn, Roman; Dvornik, Mykola; Mazraati, Hamid; Houshang, Afshin; Jiang, Sheng; Nguyen, T. N. Anh; Goering, Eberhard; Schütz, Gisela; Gräfe, Joachim; Åkerman, Johan

2018-05-01

Magnetic droplets are nontopological dynamical solitons that can be nucleated in nanocontact based spin torque nano-oscillators (STNOs) with perpendicular magnetic anisotropy free layers. While theory predicts that the droplet should be of the same size as the nanocontact, its inherent drift instability has thwarted attempts at observing it directly using microscopy techniques. Here, we demonstrate highly stable magnetic droplets in all-perpendicular STNOs and present the first detailed droplet images using scanning transmission X-ray microscopy. In contrast to theoretical predictions, we find that the droplet diameter is about twice as large as the nanocontact. By extending the original droplet theory to properly account for the lateral current spread underneath the nanocontact, we show that the large discrepancy primarily arises from current-in-plane Zhang-Li torque adding an outward pressure on the droplet perimeter. Electrical measurements on droplets nucleated using a reversed current in the antiparallel state corroborate this picture.

[The modern TCM education of Tianjin].

PubMed

Xie, J

2016-11-28

School education had gradually become the mainstream of medical education at the turn of the Qing Dynasty and Republican period. In Tianjin, there were western medical education, including the Peiyang Medical College, Army Medical College, and Lu's Medical School, whereas, there was no traditional medical school at all. To check this defect, two private TCM medical schools, the Learning School of TCM, and the Tianjin TCM Institution were set up by Chen Zedong and Gu Jinren respectively through persistent endeavor. Meanwhile, correspondence school of TCM were established by Zhang Xichun, Wei Jiaqian, and Ma Leshan. Though more TCM schools were planned, including Tianjin Private School of TCM by Lu Zongren and Qian Boquan, North China Professional TCM School by Zhang Yinqi and other colleagues, TCM Professional School by Zhang Dianju and the Tianjin Private Acu-Moxibustion School by Zhang Lihui, etc. All these did make their contributions to the training of TCM talents in modern times.

Study of sea-surface slope distribution and its effect on radar backscatter based on Global Precipitation Measurement Ku-band precipitation radar measurements

NASA Astrophysics Data System (ADS)

Yan, Qiushuang; Zhang, Jie; Fan, Chenqing; Wang, Jing; Meng, Junmin

2018-01-01

The collocated normalized radar backscattering cross-section measurements from the Global Precipitation Measurement (GPM) Ku-band precipitation radar (KuPR) and the winds from the moored buoys are used to study the effect of different sea-surface slope probability density functions (PDFs), including the Gaussian PDF, the Gram-Charlier PDF, and the Liu PDF, on the geometrical optics (GO) model predictions of the radar backscatter at low incidence angles (0 deg to 18 deg) at different sea states. First, the peakedness coefficient in the Liu distribution is determined using the collocations at the normal incidence angle, and the results indicate that the peakedness coefficient is a nonlinear function of the wind speed. Then, the performance of the modified Liu distribution, i.e., Liu distribution using the obtained peakedness coefficient estimate; the Gaussian distribution; and the Gram-Charlier distribution is analyzed. The results show that the GO model predictions with the modified Liu distribution agree best with the KuPR measurements, followed by the predictions with the Gaussian distribution, while the predictions with the Gram-Charlier distribution have larger differences as the total or the slick filtered, not the radar filtered, probability density is included in the distribution. The best-performing distribution changes with incidence angle and changes with wind speed.

Pragmatism, Pedagogy, and Community Service Learning

ERIC Educational Resources Information Center

Yoder, Scot D.

2016-01-01

In this paper I explore Goodwin Liu's proposal to ground the pedagogy of service-learning in the epistemology of pragmatism from the perspective of a reflective practitioner. I review Liu's epistemology and his claim that from within it three features common to service-learning--community, diversity, and engagement--become pedagogical virtues. I…

Parametric Instabilities of Electron Cyclotron Waves in Plasmas.

DTIC Science & Technology

1980-03-01

Perkins, PPPL -1578 (1979). 7. C. S. Liu, in Advances in Plasma Physics, edited by A. Simon and W. B. Thompson (Wiley, N. Y. 1976) Vol. 6. p. 121. 8. V. K. Tripathi, C. S. Liu and C. Grebogi, Phys. Fluids 22, 301 (1979). II II II1I. .. ,

Laboratory Simulations of CME-Solar Wind Interactions Using a Coaxial Gun and Background Plasma

NASA Astrophysics Data System (ADS)

Wallace, B. H.; Zhang, Y.; Fisher, D.; Gilmore, M.

2016-12-01

Understanding and predicting solar coronal mass ejections (CMEs) is of critical importance for mitigating their disruptive behavior on ground- and space-based technologies. While predictive models of CME propagation and evolution have relied primarily on sparse in-situ data along with ground and satellite images for validation purposes, emerging laboratory efforts have shown that CME-like events can be created with parameters applicable to the solar regime that may likewise aid in predictive modeling. A modified version of the coaxial plasma gun from the Plasma Bubble Expansion Experiment (PBEX) [A. G. Lynn, Y. Zhang, S. C. Hsu, H. Li, W. Liu, M. Gilmore, and C. Watts, Bull. Amer. Phys. Soc. 52, 53 (2007)] will be used in conjunction with the Helicon-Cathode (HelCat) basic plasma science device in order to observe the magnetic characteristics of CMEs as they propagate through the solar wind. The evolution of these interactions will be analyzed using a multi-tip Langmuir probe array, a 33-position B-dot probe array, and a high speed camera. The results of this investigation will be used alongside the University of Michigan's BATS-R-US 3-D MHD numerical code, which will be used to perform simulations of the coaxial plasma gun experiment. The results of these two approaches will be compared in order to validate the capabilities of the BATS-R-US code as well as to further our understanding of magnetic reconnection and other processes that take place as CMEs propagate through the solar wind. The details of the experimental setup as well as the analytical approach are discussed.

Early growth response-1 negative feedback regulates skeletal muscle postprandial insulin sensitivity via activating Ptp1b transcription.

PubMed

Wu, Jing; Tao, Wei-Wei; Chong, Dan-Yang; Lai, Shan-Shan; Wang, Chuang; Liu, Qi; Zhang, Tong-Yu; Xue, Bin; Li, Chao-Jun

2018-03-15

Postprandial insulin desensitization plays a critical role in maintaining whole-body glucose homeostasis by avoiding the excessive absorption of blood glucose; however, the detailed mechanisms that underlie how the major player, skeletal muscle, desensitizes insulin action remain to be elucidated. Herein, we report that early growth response gene-1 ( Egr-1) is activated by insulin in skeletal muscle and provides feedback inhibition that regulates insulin sensitivity after a meal. The inhibition of the transcriptional activity of Egr-1 enhanced the phosphorylation of the insulin receptor (InsR) and Akt, thus increasing glucose uptake in L6 myotubes after insulin stimulation, whereas overexpression of Egr-1 decreased insulin sensitivity. Furthermore, deletion of Egr-1 in the skeletal muscle improved systemic insulin sensitivity and glucose tolerance, which resulted in lower blood glucose levels after refeeding. Mechanistic analysis demonstrated that EGR-1 inhibited InsR phosphorylation and glucose uptake in skeletal muscle by binding to the proximal promoter region of protein tyrosine phosphatase-1B (PTP1B) and directly activating transcription. PTP1B knockdown largely restored insulin sensitivity and enhanced glucose uptake, even under conditions of EGR-1 overexpression. Our results indicate that EGR-1/PTP1B signaling negatively regulates postprandial insulin sensitivity and suggest a potential therapeutic target for the prevention and treatment of excessive glucose absorption.-Wu, J., Tao, W.-W., Chong, D.-Y., Lai, S.-S., Wang, C., Liu, Q., Zhang, T.-Y., Xue, B., Li, C.-J. Early growth response-1 negative feedback regulates skeletal muscle postprandial insulin sensitivity via activating Ptp1b transcription.

EMC HWRF Weekly Meeting Homepage

Science.gov Websites

structure using idealized HWRF simulations with GFS and MYJ PBL schemes by Jun Zhang (HRD/AOML) NOAA- MoES Zhan Zhang(EMC) (NOTE: Links open presentations in a new window) Please e-mail comments, questions, or

International Aviation (Selected Articles)

DTIC Science & Technology

1991-06-05

The Manufacturing Capabilities of the Shanghai Aviation Company Leap to a New Level, by Yang Xinbang Zhang Shiyuan , Zheng Huilin............9 Setting...international cooperation. 8 THE MANUFACTURING CAPABILITIES OF THE SHANGHAI AVIATION COMPANY LEAP TO A NEW LEVEL Yang Xinbang Zhang Shiyuan Zheng

Regional-scale simulation of transport and transformations of semi-volatile polycyclic aromatic hydrocarbons (PAHs) in East Asia: diurnal variations investigation

NASA Astrophysics Data System (ADS)

Mu, Qing; Lammel, Gerhard; Cheng, Yafang

2015-04-01

Semi-volatile PAHs are major pollutants of urban air, mostly regionally transported and reaching remote environments[1]. Some semi-volatile PAHs are carcinogenic. About 22% of global PAHs emissions are in China. The transport and sinks (atmospheric reactions, deposition) of semi-volatile PAHs in East Asia are studied using a modified version of the Weather Research and Forecasting model coupled with chemistry (WRF/Chem [2]). For this purpose, PAHs' gas and particulate phase chemical reactions and dry and wet deposition processes are included. We use emissions of 2008 [3] which include technical combustion processes (coal, oil, gas, waste and biomass) and open fires and apply diurnal time functions as those of black carbon. The model was run for phenanthrene (3-ring PAH, p = 1.5×10-2 Pa at 298 K) and benzo(a)pyrene (5-ring PAH, p = 7×10-7 Pa) for July 2013 with hourly output and 27 km horizontal grid spacing. The comparison of model predicted phenanthrene concentrations with measurements at a rural site near Beijing (own data, unpublished) validates the model's ability to simulate diurnal variations of gaseous PAHs. The model's performance is better in simulating day time than night time gaseous PAHs. The concentrations of PAHs had experienced significant diurnal variations in rural and remote areas of China. Elevated concentration levels of 40-60 ng m-3 for phenanthrene and 1-10 ng m-3 for benzo(a)pyrene are predicted in Shanxi, Guizhou, the North China Plain, the Sichuan Basin and Chongqing metropolitan areas due to the high emission densities at those locations. References [1] Keyte, I.J., Harrison, R.M., and Lammel, G., 2013: Chemical reactivity and long-range transport potential of polycyclic aromatic hydrocarbons - a review, Chem. Soc. Rev., 42, 9333-9391. [2] Grell, G.A, Peckham, S.E, Schmitz, R, McKeen, S.A, Frost, G, Skamarock, W.C, and Eder, B., 2005: Fully coupled online chemistry within the WRF model, Atmos. Environ., 39, 6957-6975. [3] Shen, H. Z., Huang, Y., Wang, R., Zhu, D., Li, W., Shen, G. F., Wang, B., Zhang, Y. Y., Chen, Y. C., Lu, Y., Chen, H., Li, T. C., Sun, K., Li, B. G., Liu, W. X., Liu, J. F., and Tao, S., 2013: Global atmospheric emissions of polycyclic aromatic hydrocarbons from 1960 to 2008 and future predictions, Environ. Sci. Technol., 47, 6415-6424.

High Frequency Magneto Dielectric Effects In Self Assembled Ferrite Ferroelectric Core Shell Nanoparticles

DTIC Science & Technology

2014-09-10

2008). 2 Y. Yang, S. Priya, J. Li , and D. Viehland, J. Am. Ceram. Soc. 92, 1552 (2009). 3 J. Ma, J. Hu, Z. Li , and C. W. Nan, Adv. Mater. 23, 1062...2013) 9 Yongke Yan, Yuan Zhou, and Shashank Priya, Appl. Phys. Lett. 104, 032911 (2014) 10 Gaojian Wu, Tianxiang Nan, Ru Zhang, Ning Zhang, Shandong Li ...Kim, L. T. Schelhas, S. Keller, J. L. Hockel, S. H. Tolbert, and G. P. Carman, Nano Lett. 13, 884 (2013). 13 S. Zhang, Y. G. Zhao, P. S. Li , J. J

Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways.

PubMed

Zhang, Yong; Ma, Chen; Zhao, Jie; Xu, Haiyan; Hou, Qiangchuan; Zhang, Heping

2017-04-11

The incidence of colon cancer has increased considerably and the intestinal microbiota participate in the development of colon cancer. We showed that the L. casei Zhang or vitamin K2 (Menaquinone-7) intervention significantly alleviated intestinal tumor burden in mice. This was associated with increased serum adiponectin levels in both treatments. But osteocalcin level was only increased by L. casei Zhang. Furthermore, the anti-carcinogenic actions of L. casei Zhang were mediated by hepatic Chloride channel-3(CLCN3)/Nuclear Factor Kappa B(NF-κB) and intestinal Claudin15/Chloride intracellular channel 4(CLIC4)/Transforming Growth Factor Beta(TGF-β) signaling, while the vitamin K2 effect involved a hepatic Vitamin D Receptor(VDR)-phosphorylated AMPK signaling pathway. Fecal DNA sequencing by the Pacbio RSII method revealed there was significantly lower Helicobacter apodemus, Helicobacter mesocricetorum, Allobaculum stercoricanis and Adlercreutzia equolifaciens following both interventions compared to the model group. Moreover, different caecum acetic acid and butyric acid levels and enrichment of other specific microbes also determined the activity of the different regulatory pathways. Together these data show that L. casei Zhang and Vitamin K2 can suppress gut risk microbes and promote beneficial microbial metabolites to reduce colonic tumor development in mice.

Differences in Birth Weight Associated with the 2008 Beijing Olympics Air Pollution Reduction: Results from a Natural Experiment

PubMed Central

Liu, Kaibo; Zhang, Jinliang; Thurston, Sally W.; Stevens, Timothy P.; Pan, Ying; Kane, Cathleen; Weinberger, Barry; Ohman-Strickland, Pamela; Woodruff, Tracey J.; Duan, Xiaoli; Assibey-Mensah, Vanessa; Zhang, Junfeng

2015-01-01

Background Previous studies have reported decreased birth weight associated with increased air pollutant concentrations during pregnancy. However, it is not clear when during pregnancy increases in air pollution are associated with the largest differences in birth weight. Objectives Using the natural experiment of air pollution declines during the 2008 Beijing Olympics, we evaluated whether having specific months of pregnancy (i.e., 1st…8th) during the 2008 Olympics period was associated with larger birth weights, compared with pregnancies during the same dates in 2007 or 2009. Methods Using n = 83,672 term births to mothers residing in four urban districts of Beijing, we estimated the difference in birth weight associated with having individual months of pregnancy during the 2008 Olympics (8 August–24 September 2008) compared with the same dates in 2007 and 2009. We also estimated the difference in birth weight associated with interquartile range (IQR) increases in mean ambient particulate matter ≤ 2.5 μm in aerodynamic diameter (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) concentrations during each pregnancy month. Results Babies whose 8th month of gestation occurred during the 2008 Olympics were, on average, 23 g larger (95% CI: 5 g, 40 g) than babies whose 8th month occurred during the same calendar dates in 2007 or 2009. IQR increases in PM2.5 (19.8 μg/m3), CO (0.3 ppm), SO2 (1.8 ppb), and NO2 (13.6 ppb) concentrations during the 8th month of pregnancy were associated with 18 g (95% CI: –32 g, –3 g), 17 g (95% CI: –28 g, –6 g), 23 g (95% CI: –36 g, –10 g), and 34 g (95% CI: –70 g, 3 g) decreases in birth weight, respectively. We did not see significant associations for months 1–7. Conclusions Short-term decreases in air pollution late in pregnancy in Beijing during the 2008 Summer Olympics, a normally heavily polluted city, were associated with higher birth weight. Citation Rich DQ, Liu K, Zhang J, Thurston SW, Stevens TP, Pan Y, Kane C, Weinberger B, Ohman-Strickland P, Woodruff TJ, Duan X, Assibey-Mensah V, Zhang J. 2015. Differences in birth weight associated with the 2008 Beijing Olympics air pollution reduction: results from a natural experiment. Environ Health Perspect 123:880–887; http://dx.doi.org/10.1289/ehp.1408795 PMID:25919693

Electrical Transport Properties of Polycrystalline Monolayer Molybdenum Disulfide

DTIC Science & Technology

2014-07-14

Lou, Sina Najmaei, Matin Amani, Matthew L. Chin, Zheng Se. TASK NUMBER Liu Sf. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAMES AND ADDRESSES 8...Transport Properties of Polycrystalline Monolayer Molybdenum Disulfide Sina Najmaei,t.§ Matin Ama ni,M Matthew L. Chin,* Zhe ng liu/ ·"·v: A. Gle n

Causation Fallacy 2.0: Revisiting the Myth and Math of Affirmative Action

ERIC Educational Resources Information Center

Hughes, Sherick; Thompson Dorsey, Dana N.; Carrillo, Juan F.

2016-01-01

Justice Goodwin Liu reexamined seminal affirmative action in higher education legal cases beginning with the landmark 1978 case, "Regents of the University of California v. Bakke" and leading up to the U.S. Supreme Court's 2003 decision in "Gratz v. Bollinger." Liu argued that the "Bakke and Gratz" lawsuits were…

The Effect of Spray Initial Conditions on Heat Release and Emissions in LDI CFD Calculations (Preprint)

DTIC Science & Technology

2008-06-01

Shih, T.-H., Povinelli , L. A., Liu, N.-S and Chen, K.-H., (2000), “Generalized Wall Function for...J. Marek, T. D. Smith, N.-S. Liu, and L. A. Povinelli (NASA, Glenn Research Center, Cleveland, OH, “A Study of Hydrogen/Air Combustor Using NCC

When Liu Hui Meets Archimedes: Students' Epistemological and Cultural Interpretations of Mathematics

ERIC Educational Resources Information Center

Liu, Po-Hung

2014-01-01

The present study aimed to investigate in what way and to what extent Taiwanese college students' epistemological views of mathematics had evolved during a history-based liberal arts mathematics course titled: "When Liu Hui Meets Archimedes--Development of Eastern and Western Mathematics." The course was designed to help college students…

Second Order Accurate Finite Difference Methods

DTIC Science & Technology

1984-08-20

34Nonlinear Modulation of Torsional Waves in Elastic Rods," 3. Phys. Soc. Japan, V. 42, No. 6, pp. 2056-2064, 1977. 10. S. S. Antman and T. Liu. "Travelling...waves in a circular rod. The equations have been solved for coupling effects in torsional and longitudinal waves. Antman and Liu (10) have studied

Retraction Note to: Ultra-High Strength and Ductile Lamellar-Structured Powder Metallurgy Binary Ti-Ta Alloys

NASA Astrophysics Data System (ADS)

Liu, Yong; Xu, Shenghang; Wang, Xin; Li, Kaiyang; Liu, Bin; Wu, Hong; Tang, Huiping

2018-05-01

The editors and authors have retracted the article, "Ultra-High Strength and Ductile Lamellar-Structured Powder Metallurgy Binary Ti-Ta Alloys" by Yong Liu, Shenghang Xu, Xin Wang, Kaiyang Li, Bin Liu, Hong Wu, and Huiping Tang (https://doi.org/10.1007/s11837-015-1801-1).

Simultaneous Generalizations of the Theorems of Ceva and Menelaus for Field Planes

ERIC Educational Resources Information Center

Houston, Kelly B.; Powers, Robert C.

2009-01-01

In 1992, Klamkin and Liu proved a very general result in the Extended Euclidean Plane that contains the theorems of Ceva and Menelaus as special cases. In this article, we extend the Klamkin and Liu result to projective planes "PG"(2, F) where F is a field. (Contains 2 figures.)

Uncertainty and perspectives in studies of atmospheric nitrogen deposition in China: A response to Liu et al. (2015).

PubMed

He, Nianpeng; Zhu, Jianxing; Wang, Qiufeng

2015-07-01

In this paper, we have formally responded to the speculation in "Liu et al. suspect that Zhu et al. (2015) may have underestimated dissolved organic N but overestimated total particulate N in wet deposition in China" by Liu et al. (2015). Here, we first discussed the uncertainty and plausible reasons of atmospheric deposition in China, which have been reported in different studies. We disagree with their interpretation on some points. Firstly, the difficulties in quality control from sampling to analyzing are common to all studies regarding atmospheric deposition, including the studies cited by Liu et al. (2015). More importantly, their discussion did not fully consider the apparent influence of different scaling-up methods (from an observation site scale to a national scale) on estimations of atmospheric N deposition in China. Furthermore, we provided the optimal approaches to resolve these challenges discussed in order to promote the related studies of atmospheric N deposition in China in the future. Copyright © 2015 Elsevier B.V. All rights reserved.

An improved and effective secure password-based authentication and key agreement scheme using smart cards for the telecare medicine information system.

PubMed

Das, Ashok Kumar; Bruhadeshwar, Bezawada

2013-10-01

Recently Lee and Liu proposed an efficient password based authentication and key agreement scheme using smart card for the telecare medicine information system [J. Med. Syst. (2013) 37:9933]. In this paper, we show that though their scheme is efficient, their scheme still has two security weaknesses such as (1) it has design flaws in authentication phase and (2) it has design flaws in password change phase. In order to withstand these flaws found in Lee-Liu's scheme, we propose an improvement of their scheme. Our improved scheme keeps also the original merits of Lee-Liu's scheme. We show that our scheme is efficient as compared to Lee-Liu's scheme. Further, through the security analysis, we show that our scheme is secure against possible known attacks. In addition, we simulate our scheme for the formal security verification using the widely-accepted AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our scheme is secure against passive and active attacks.

Nuclear Structure in China 2010

NASA Astrophysics Data System (ADS)

Bai, Hong-Bo; Meng, Jie; Zhao, En-Guang; Zhou, Shan-Gui

2011-08-01

Personal view on nuclear physics research / Jie Meng -- High-spin level structures in [symbol]Zr / X. P. Cao ... [et al.] -- Constraining the symmetry energy from the neutron skin thickness of tin isotopes / Lie-Wen Chen ... [et al.] -- Wobbling rotation in atomic nuclei / Y. S. Chen and Zao-Chun Gao -- The mixing of scalar mesons and the possible nonstrange dibaryons / L. R. Dai ... [et al.] -- Net baryon productions and gluon saturation in the SPS, RHIC and LHC energy regions / Sheng-Qin Feng -- Production of heavy isotopes with collisions between two actinide nuclides / Z. Q. Feng ... [et al.] -- The projected configuration interaction method / Zao-Chun Gao and Yong-Shou Chen -- Applications of Nilsson mean-field plus extended pairing model to rare-earth nuclei / Xin Guan ... [et al.] -- Complex scaling method and the resonant states / Jian-You Guo ... [et al.] -- Probing the equation of state by deep sub-barrier fusion reactions / Hong-Jun Hao and Jun-Long Tian -- Doublet structure study in A[symbol]105 mass region / C. Y. He ... [et al.] -- Rotational bands in transfermium nuclei / X. T. He -- Shape coexistence and shape evolution [symbol]Yb / H. Hua ... [et al.] -- Multistep shell model method in the complex energy plane / R. J. Liotta -- The evolution of protoneutron stars with kaon condensate / Ang Li -- High spin structures in the [symbol]Lu nucleus / Li Cong-Bo ... [et al.] -- Nuclear stopping and equation of state / QingFeng Li and Ying Yuan -- Covariant description of the low-lying states in neutron-deficient Kr isotopes / Z. X. Li ... [et al.] -- Isospin corrections for superallowed [symbol] transitions / HaoZhao Liang ... [et al.] -- The positive-parity band structures in [symbol]Ag / C. Liu ... [et al.] -- New band structures in odd-odd [symbol]I and [symbol]I / Liu GongYe ... [et al.] -- The sd-pair shell model and interacting boson model / Yan-An Luo ... [et al.] -- Cross-section distributions of fragments in the calcium isotopes projectile fragmentation at the intermediate energy / C. W. Ma ... [et al.].Systematic study of spin assignment and dynamic moment of inertia of high-j intruder band in [symbol]In / K. Y. Ma ... [et al.] -- Signals of diproton emission from the three-body breakup channel of [symbol]Al and [symbol]Mg / Ma Yu-Gang ... [et al.] -- Uncertainties of Th/Eu and Th/Hf chronometers from nucleus masses / Z. M. Niu ... [et al.] -- The chiral doublet bands with [symbol] configuration in A[symbol]100 mass region / B. Qi ... [et al.] -- [symbol] formation probabilities in nuclei and pairing collectivity / Chong Qi -- A theoretical prospective on triggered gamma emission from [symbol]Hf[symbol] isomer / ShuiFa Shen ... [et al.] -- Study of nuclear giant resonances using a Fermi-liquid method / Bao-Xi Sun -- Rotational bands in doubly odd [symbol]Sb / D. P. Sun ... [et al.] -- The study of the neutron N=90 nuclei / W. X. Teng ... [et al.] -- Dynamical modes and mechanisms in ternary reaction of [symbol]Au+[symbol]Au / Jun-Long Tian ... [et al.] -- Dynamical study of X(3872) as a D[symbol] molecular state / B. Wang ... [et al.] -- Super-heavy stability island with a semi-empirical nuclear mass formula / N. Wang ... [et al.] -- Pseudospin partner bands in [symbol]Sb / S. Y. Wang ... [et al.] -- Study of elastic resonance scattering at CIAE / Y. B. Wang ... [et al.] -- Systematic study of survival probability of excited superheavy nuclei / C. J. Xia ... [et al.] -- Angular momentum projection of the Nilsson mean-field plus nearest-orbit pairing interaction model / Ming-Xia Xie ... [et al.] -- Possible shape coexistence for [symbol]Sm in a reflection-asymmetric relativistic mean-field approach / W. Zhang ... [et al.] -- Nuclear pairing reduction due to rotation and blocking / Zhen-Hua Zhang -- Nucleon pair approximation of the shell model: a review and perspective / Y. M. Zhao ... [et al.] -- Band structures in doubly odd [symbol]I / Y. Zheng ... [et al.] -- Lifetimes of high spin states in [symbol]Ag / Y. Zheng ... [et al.] -- Effect of tensor interaction on the shell structure of superheavy nuclei / Xian-Rong Zhou ... [et al.].

On Complete Control and Synchronization of Zhang Chaotic System with Uncertain Parameters using Adaptive Control Method

NASA Astrophysics Data System (ADS)

Tirandaz, Hamed

2018-03-01

Chaos control and synchronization of chaotic systems is seemingly a challenging problem and has got a lot of attention in recent years due to its numerous applications in science and industry. This paper concentrates on the control and synchronization problem of the three-dimensional (3D) Zhang chaotic system. At first, an adaptive control law and a parameter estimation law are achieved for controlling the behavior of the Zhang chaotic system. Then, non-identical synchronization of Zhang chaotic system is provided with considering the Lü chaotic system as the follower system. The synchronization problem and parameters identification are achieved by introducing an adaptive control law and a parameters estimation law. Stability analysis of the proposed method is proved by the Lyapanov stability theorem. In addition, the convergence of the estimated parameters to their truly unknown values are evaluated. Finally, some numerical simulations are carried out to illustrate and to validate the effectiveness of the suggested method.

GENETIC BACKGROUND BUT NOT METALLOTHIONEIN PHENOTYPE DICTATES SENSITIVITY TO CADMIUM-INDUCED TESTICULAR INJURY IN MICE

EPA Science Inventory

Genetic Background but not Metallothionein Phenotype Dictates Sensitivity to
Cadmium-Induced Testicular Injury in Mice

Jie Liu1,2, Chris Corton3, David J. Dix4, Yaping Liu1, Michael P. Waalkes2
and Curtis D. Klaassen1

ABSTRACT

Parenteral administrati...

BMP7 Induces Dormancy of Prostatic Tumor Stem Cell in Bone

DTIC Science & Technology

2013-07-01

Watabe, Shigeru Hirota, Sudha K. Pai, Wen Liu, Koji Fukuda, Christopher Chambers, Andrew Wilber and Kounosuke Watabe “Bone Figure 7. Expression of BMP7...Hiroshi Okuda,1 Fei Xing,1 Puspa R. Pandey,1 Misako Watabe,1 Shigeru Hirota,2 Sudha K. Pai,1 Wen Liu,1 Koji Fukuda,1 Christopher Chambers,1 Andrew

Ovarian Tumor-Stroma Interactions in an In Vivo Orthotopic Model

DTIC Science & Technology

2012-08-01

32. 7. Zheng X, Cui XX, Avila GE, Huang MT, Liu Y, Patel J, Kong AN, Paulino R, Shih WJ, Lin Y, Rabson AB, Reddy BS, Conney AH. Atorvastatin and...Shih WJ, Huang MT, Liu Y, Rabson A, Reddy B, Yang CS, Conney AH. Atorvastatin and celecoxib in combination inhibits the progression of androgen

An Improved Arbitrated Quantum Scheme with Bell States

NASA Astrophysics Data System (ADS)

Zhang, Yingying; Zeng, Jiwen

2018-04-01

In 2014, Liu et al. (In. J. Thero. phys. 53(5); 1569-1579. 2014) proposed an arbitrated quantum signature scheme (Liu'14) with Bell states by utilizing a new quantum one-time pad algorithm. It claimed that it can resist the receiver's existential forgery attack and no party has chances to change the message and its signature without being discovered. Recently, Xu and Zou (In. J. Thero. phys. 55; 4142-4156. 2016) analyzed above scheme and demonstrated that it can't resist the signer's disavowal and the receiver's existential forgery. But, the authors didn't give a method to solve it. In this paper, we will give an improved arbitrated quantum signature scheme to make up the loopholes in Liu'14.

Globalism and HRD. Symposium.

ERIC Educational Resources Information Center

2002

This document contains three papers from a symposium on globalization and human resource development (HRD). "Challenges and Strategies of Developing Human Resources in the Surge of Globalization: A Case of the People's Republic of China" (De Zhang, Baiyin Yang, Yichi Zhang) analyzes the challenges and strategies of HRD in China and…

Modeling of Ionosphere Effects of Geomagnetic Storm Sequence on September 9-14, 2005 in View of Solar Flares and Dependence of Model Input Parameters from AE-and Kp-indices

NASA Astrophysics Data System (ADS)

Klimenko, Maxim; Klimenko, Vladimir; Ratovsky, Konstantin; Goncharenko, Larisa

Earlier by Klimenko et al., 2009 under carrying out the calculations of the ionospheric effects of storm sequence on September 9-14, 2005 the model input parameters (potential difference through polar caps, field-aligned currents of the second region and particle precipitation fluxes and energy) were set as function of Kp-index of geomagnetic activity. The analyses of obtained results show that the reasons of quantitative distinctions of calculation results and observations can be: the use of 3 hour Kp-index at the setting of time dependence of model input parameters; the dipole approach of geomagnetic field; the absence in model calculations the effects of the solar flares, which were taken place during the considered period. In the given study the model input parameters were set as function of AE-and Kp-indices of geomagnetic activity according to different empirical models and morphological representations Feshchenko and Maltsev, 2003; Cheng et al., 2008; Zhang and Paxton, 2008. At that, we taken into account the shift of field-aligned currents of the second region to the lower latitudes as by Sojka et al., 1994 and 30 min. time delay of variations of the field-aligned currents of second region relative to the variations of the potential difference through polar caps at the storm sudden commencement phase. Also we taken into account the ionospheric effects of solar flares. Calculation of ionospheric effects of storm sequence has been carried out with use of the Global Self-Consistent Model of the Thermosphere, Ionosphere and Protonosphere (GSM TIP) developed in WD IZMIRAN (Nam-galadze et al., 1988). We carried out the comparison of calculation results with experimental data. This study is supported by RFBR grant 08-05-00274. References Cheng Z.W., Shi J.K., Zhang T.L., Dunlop M. and Liu Z.X. Relationship between FAC at plasma sheet boundary layers and AE index during storms from August to October, 2001. Sci. China Ser. E-Tech. Sci., 2008, Vol. 51, No. 7, 842-848. Feshchenko E.Yu., Maltsev Yu.P. Relations of the polar cap voltage to the geophysical activity. Physics of Auroral Phenomena: XXVI Annual Seminar (February 25-28, 2003): Proc./PGI KSC RAS. Apatity, 2003, 59-61. Klimenko M.V., Klimenko V.V., Ratovsky K.G., and Goncharenko L.P. Numerical modeling of ionospheric parameters during sequence of geomagnetic storms on September 9-14, 2005. Physics of Auroral Phenomena: XXXII Annual Seminar (March 3-6, 2009): Proc./PGI KSC RAS. Apatity, 2009, 162-165. Namgaladze A.A., Korenkov Yu.N., Klimenko V.V., Karpov I.V., Bessarab F.S., Surotkin V.A., Glushenko T.A., Naumova N.M. Global model of the thermosphere-ionosphere-protonosphere system. Pure and Applied Geophysics (PAGEOPH), 1988, Vol. 127, No. 2/3, 219-254. Sojka J.J., Schunk R.W., Denig W.F. Ionospheric response to the sustained high geomagnetic activity during the March '89 great storm. J. Geophys. Res., 1994, Vol. 99, No. A11, 21341-21352. Zhang Y., Paxton L.J. An empirical Kp-dependent global auroral model based on TIMED/GUVI FUV data. J. Atmos. Solar-Terr. Phys., 2008, Vol. 70, 1231-1242.

Collaborative Learning. Research to Practice Brief

ERIC Educational Resources Information Center

Lawrence, K. S.

2016-01-01

A Fully Integrated Educational System practices collaborative learning among all peers. The study summarized in this report (Zhang, X., Anderson, R. C., Morris, J., Miller, B., Nguyen-Janiel, K. T., Lin, T., Zhang, J., Jadallah, M., Scott, T., Sun, J., Latawjec, B., Ma, S., Grabow, K., & Hsu, J. Y. (2016). "Improving children's competence…

78 FR 58519 - Denial of Export Privileges; Sixing Liu

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... International Emergency Economic Powers Act (50 U.S.C. 1701-1706); 18 U.S.C. 793, 794 or 798; section 4(b) of... Powers Act (50 U.S.C. 1701, et seq. (2006 & Supp. IV 2010)). I have received notice of Liu's conviction... the Regulations with knowledge or reason to know that the item will be, or is intended to be, exported...

In Pursuit of Professionalism in the Field of Chemistry Education in China: The Story of Zhixin Liu

ERIC Educational Resources Information Center

Wei, Bing

2012-01-01

In China, science educators as a professional group were originally referred to as academic staff responsible for teaching the subject-based science teaching methods course at the related science departments at teachers' universities. In this study, a biographic method was used to approach the professional life of Zhixin Liu, who was a senior…

Quantum Material Properties of 4d and 5d Transition Metal Oxides and Potential Applications

DTIC Science & Technology

2015-05-26

11 2009): 0. doi: 10.1103/PhysRevB.80.184505 Y. Liu, I. G. Deac, P. Khalifah, R. J. Cava, Y. A. Ying, P. Schiffer , K. D. Nelson. Possible observation...Yiqun A. Ying, Karl Nelson, Iosef G. Deac, Peter Schiffer , Peter Khalifah, Robert J. Cava, and Ying Liu, "Magneto electrical transport properties and

Resolving Confined 7Li Dynamics of Uranyl Peroxide Capsule U 24

DOE PAGES

Xie, Jing; Neal, Harrison A.; Szymanowski, Jennifer; ...

2018-04-18

Here, we obtained a kerosene-soluble form of the lithium salt [UO 2(O 2)(OH) 2] 24 phase (Li-U 24), by adding cetyltrimethylammonium bromide surfactant to aqueous Li-U 24. Interestingly, its variable-temperature solution 7Li NMR spectroscopy resolves two narrowly spaced resonances down to –10 °C, which shift upfield with increasing temperature, and finally coalesce at temperatures > 85 °C. Comparison with solid-state NMR demonstrates that the Li dynamics in the Li-U 24-CTA phase involves only exchange between different local encapsulated environments. This behavior is distinct from the rapid Li exchange dynamics observed between encapsulated and external Li environments for Li-U 24 inmore » both the aqueous and the solid-state phases. Density functional theory calculations suggest that the two experimental 7Li NMR chemical shifts are due to Li cations coordinated within the square and hexagonal faces of the U 24 cage, and they can undergo exchange within the confined environment, as the solution is heated. Very different than U 24 in aqueous media, there is no evidence that the Li cations exit the cage, and therefore, this represents a truly confined space.« less

Resolving Confined 7Li Dynamics of Uranyl Peroxide Capsule U 24

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Jing; Neal, Harrison A.; Szymanowski, Jennifer

Here, we obtained a kerosene-soluble form of the lithium salt [UO 2(O 2)(OH) 2] 24 phase (Li-U 24), by adding cetyltrimethylammonium bromide surfactant to aqueous Li-U 24. Interestingly, its variable-temperature solution 7Li NMR spectroscopy resolves two narrowly spaced resonances down to –10 °C, which shift upfield with increasing temperature, and finally coalesce at temperatures > 85 °C. Comparison with solid-state NMR demonstrates that the Li dynamics in the Li-U 24-CTA phase involves only exchange between different local encapsulated environments. This behavior is distinct from the rapid Li exchange dynamics observed between encapsulated and external Li environments for Li-U 24 inmore » both the aqueous and the solid-state phases. Density functional theory calculations suggest that the two experimental 7Li NMR chemical shifts are due to Li cations coordinated within the square and hexagonal faces of the U 24 cage, and they can undergo exchange within the confined environment, as the solution is heated. Very different than U 24 in aqueous media, there is no evidence that the Li cations exit the cage, and therefore, this represents a truly confined space.« less

Taxonomic position of Hormaphis similibetulae Qiao & Zhang, 2004 (Hemiptera, Aphididae): molecular and biological evidences

PubMed Central

Chen, Jing; Jiang, Li-Yun; Qiao, Ge-Xia

2011-01-01

Abstract The taxonomic position of Hormaphis similibetulae Qiao & Zhang, 2004 has been reexamined. The phylogenetic position of Hormaphis similibetulae was inferred by maximum parsimony, maximum likelihood and Bayesian analyses on the basis of partial nuclear elongation factor-1α and mitochondrial tRNA leucine/cytochrome oxidase II sequences. The results showed that this species fell into the clade of Hamamelistes species, occupying a basal position, and was clearly distinct from other Hormaphis species. A closer relationship between Hormaphis similibetulae and Hamamelistes species was also revealed by life cycle analysis. Therefore, we conclude that Hormaphis similibetulae should be transferred to the genus Hamamelistes as Hamamelistes similibetulae (Qiao & Zhang), comb. n. PMID:21852935

SCM-Forcing Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Shaocheng; Tang, Shuaiqi; Zhang, Yunyan

2016-07-01

Single-Column Model (SCM) Forcing Data are derived from the ARM facility observational data using the constrained variational analysis approach (Zhang and Lin 1997 and Zhang et al., 2001). The resulting products include both the large-scale forcing terms and the evaluation fields, which can be used for driving the SCMs and Cloud Resolving Models (CRMs) and validating model simulations.

BUPT_PRIS at TREC 2014 Knowledge Base Acceleration Track

DTIC Science & Technology

2014-11-01

BUPT_PRIS at TREC 2014 Knowledge Base Acceleration Track Yuanyuan Qi, Ye Xu, Dongxu Zhang, Weiran Xu qiyuanyuan@bupt.edu.cn,bob.ye.xu@gmail.com...Filtering for Entity Profile Updates for TREC 2013 [2]Yan Li, Zhaozhao Wang , Baojin Yu, Yong Zhang, Ruiyang Luo,Weiran Xu, Guang Chen, Jun Guo. PRIS

Developing Models for Synchronizing the Interaction among Users, Systems and Content in Complex Information Spaces

DTIC Science & Technology

2009-10-02

October. Jansen, B. J., Zhang, M., and Zhang, Y. (2007) Brand Awareness and the Evaluation of Search Results, 16th International World Wide Web...2007) The Effect of Brand Awareness on the Evaluation of Search Engine Results, Conference on Human Factors in Computing Systems (SIGCHI), Work-in

Constitutive Modeling of the High-Temperature Flow Behavior of α-Ti Alloy Tube

NASA Astrophysics Data System (ADS)

Lin, Yanli; Zhang, Kun; He, Zhubin; Fan, Xiaobo; Yan, Yongda; Yuan, Shijian

2018-04-01

In the hot metal gas forming process, the deformation conditions, such as temperature, strain rate and deformation degree, are often prominently changed. The understanding of the flow behavior of α-Ti seamless tubes over a relatively wide range of temperatures and strain rates is important. In this study, the stress-strain curves in the temperature range of 973-1123 K and the initial strain rate range of 0.0004-0.4 s-1 were measured by isothermal tensile tests to conduct a constitutive analysis and a deformation behavior analysis. The results show that the flow stress decreases with the decrease in the strain rate and the increase of the deformation temperature. The Fields-Backofen model and Fields-Backofen-Zhang model were used to describe the stress-strain curves. The Fields-Backofen-Zhang model shows better predictability on the flow stress than the Fields-Backofen model, but there exists a large deviation in the deformation condition of 0.4 s-1. A modified Fields-Backofen-Zhang model is proposed, in which a strain rate term is introduced. This modified Fields-Backofen-Zhang model gives a more accurate description of the flow stress variation under hot forming conditions with a higher strain rate up to 0.4 s-1. Accordingly, it is reasonable to adopt the modified Fields-Backofen-Zhang model for the hot forming process which is likely to reach a higher strain rate, such as 0.4 s-1.

Constitutive Modeling of the High-Temperature Flow Behavior of α-Ti Alloy Tube

NASA Astrophysics Data System (ADS)

Lin, Yanli; Zhang, Kun; He, Zhubin; Fan, Xiaobo; Yan, Yongda; Yuan, Shijian

2018-05-01

In the hot metal gas forming process, the deformation conditions, such as temperature, strain rate and deformation degree, are often prominently changed. The understanding of the flow behavior of α-Ti seamless tubes over a relatively wide range of temperatures and strain rates is important. In this study, the stress-strain curves in the temperature range of 973-1123 K and the initial strain rate range of 0.0004-0.4 s-1 were measured by isothermal tensile tests to conduct a constitutive analysis and a deformation behavior analysis. The results show that the flow stress decreases with the decrease in the strain rate and the increase of the deformation temperature. The Fields-Backofen model and Fields-Backofen-Zhang model were used to describe the stress-strain curves. The Fields-Backofen-Zhang model shows better predictability on the flow stress than the Fields-Backofen model, but there exists a large deviation in the deformation condition of 0.4 s-1. A modified Fields-Backofen-Zhang model is proposed, in which a strain rate term is introduced. This modified Fields-Backofen-Zhang model gives a more accurate description of the flow stress variation under hot forming conditions with a higher strain rate up to 0.4 s-1. Accordingly, it is reasonable to adopt the modified Fields-Backofen-Zhang model for the hot forming process which is likely to reach a higher strain rate, such as 0.4 s-1.

The Problem of Character Education and Kohlberg's Moral Education: Critique from Dewey's Moral Deliberation

ERIC Educational Resources Information Center

Liu, Xiangdong

2014-01-01

In this article, the author examines Dewey's moral deliberation. Liu argues that Dewey's work will enrich both character education and Kohlberg's moral education. Liu focuses on character education and on Kohlberg's moral education because these are the two dominant approaches. Character education seeks to cultivate good…

Microfluidic Experiments Studying Pore Scale Interactions of Microbes and Geochemistry

NASA Astrophysics Data System (ADS)

Chen, M.; Kocar, B. D.

2016-12-01

Understanding how physical phenomena, chemical reactions, and microbial behavior interact at the pore-scale is crucial to understanding larger scale trends in groundwater chemistry. Recent studies illustrate the utility of microfluidic devices for illuminating pore-scale physical-biogeochemical processes and their control(s) on the cycling of iron, uranium, and other important elements 1-3. These experimental systems are ideal for examining geochemical reactions mediated by microbes, which include processes governed by complex biological phenomenon (e.g. biofilm formation, etc.)4. We present results of microfluidic experiments using a model metal reducing bacteria and varying pore geometries, exploring the limitations of the microorganisms' ability to access tight pore spaces, and examining coupled biogeochemical-physical controls on the cycling of redox sensitive metals. Experimental results will provide an enhanced understanding of coupled physical-biogeochemical processes transpiring at the pore-scale, and will constrain and compliment continuum models used to predict and describe the subsurface cycling of redox-sensitive elements5. 1. Vrionis, H. A. et al. Microbiological and geochemical heterogeneity in an in situ uranium bioremediation field site. Appl. Environ. Microbiol. 71, 6308-6318 (2005). 2. Pearce, C. I. et al. Pore-scale characterization of biogeochemical controls on iron and uranium speciation under flow conditions. Environ. Sci. Technol. 46, 7992-8000 (2012). 3. Zhang, C., Liu, C. & Shi, Z. Micromodel investigation of transport effect on the kinetics of reductive dissolution of hematite. Environ. Sci. Technol. 47, 4131-4139 (2013). 4. Ginn, T. R. et al. Processes in microbial transport in the natural subsurface. Adv. Water Resour. 25, 1017-1042 (2002). 5. Scheibe, T. D. et al. Coupling a genome-scale metabolic model with a reactive transport model to describe in situ uranium bioremediation. Microb. Biotechnol. 2, 274-286 (2009).

Land use allocation model considering climate change impact

NASA Astrophysics Data System (ADS)

Lee, D. K.; Yoon, E. J.; Song, Y. I.

2017-12-01

In Korea, climate change adaptation plans are being developed for each administrative district based on impact assessments constructed in various fields. This climate change impact assessments are superimposed on the actual space, which causes problems in land use allocation because the spatial distribution of individual impacts may be different each other. This implies that trade-offs between climate change impacts can occur depending on the composition of land use. Moreover, the actual space is complexly intertwined with various factors such as required area, legal regulations, and socioeconomic values, so land use allocation in consideration of climate change can be very difficult problem to solve (Liu et al. 2012; Porta et al. 2013).Optimization techniques can generate a sufficiently good alternatives for land use allocation at the strategic level if only the fitness function of relationship between impact and land use composition are derived. It has also been noted that land use optimization model is more effective than the scenario-based prediction model in achieving the objectives for problem solving (Zhang et al. 2014). Therefore in this study, we developed a quantitative tool, MOGA (Multi Objective Genetic Algorithm), which can generate a comprehensive land use allocations considering various climate change impacts, and apply it to the Gangwon-do in Korea. Genetic Algorithms (GAs) are the most popular optimization technique to address multi-objective in land use allocation. Also, it allows for immediate feedback to stake holders because it can run a number of experiments with different parameter values. And it is expected that land use decision makers and planners can formulate a detailed spatial plan or perform additional analysis based on the result of optimization model. Acknowledgments: This work was supported by the Korea Ministry of Environment (MOE) as "Climate Change Correspondence Program (Project number: 2014001310006)"

Fast Positive Breakdown, NBEs, and Lightning Initiation

NASA Astrophysics Data System (ADS)

Krehbiel, P. R.; Rison, W.; Stock, M.; Edens, H. E.; Shao, X. M.; Thomas, R. J.; Stanley, M. A.; Zhang, Y.

2016-12-01

High power narrrow bipolar events (NBEs) have been found to be produced by arelatively unknown type of discharge, called fast positive breakdown (Rison etal., 2016). The breakdown occurs with a wide range of strengths, both in terms of its broadband sferic and its VHF radiation, and is found to be theinitiating event of many and likely all lightning discharges inside storms. Itdoes not produce a conducting channel but instead appears to be produced by avolumetric system of repeated, cascading positive streamers in virgin air.That positive corona and streamers would be responsible for initiatinglightning was proposed in the 1960s by Loeb, Dawson and Winn. In the 1970sPhelps and Griffiths showed that the streamers would be self-intensifying,leading to negative breakdown being initiated back at their starting points.Petersen et al. (2008) described experimental results showing that thestreamers could be initiated by ice crystals at cold temperatures, and thephysical processes leading to the breakdown being fast has been reported inrecent modeling studies by Shi et al. (2016). In this paper we summarize the observational data in support of the abovefindings, and report on additional observations of NBEs and lightninginitiation currently being obtained at Kennedy Space Center, Florida. References: Rison W., P.R. Krehbiel M.G.Stock, H.E. Edens, X-M. Shao, R.J. Thomas,M.A. Stanley, Y. Zhang, Observations of narrow bipolar events revealhow lightning is initiated in thunderstorms, Nature Comms. 7, 2016.doi:10.1038/ncomms10721. Petersen, D., Bailey, M., Beasley, W. & Hallett, J. A brief review ofthe problem of lightning initiation and a hypothesis of initiallightning leader formation. J. Geophys. Res. 113, D17205 (2008). Shi, F., N. Liu, and H. K. Rassoul (2016), Properties of relativelylong streamers initiated from an isolated hydrometeor, J. Geophys.Res. Atmos., 121, 7284-7295, doi:10.1002/2015JD024580.

Staphylococcal enterotoxin C2 promotes osteogenesis of mesenchymal stem cells and accelerates fracture healing

PubMed Central

Wu, T.; Wang, B.; Sun, Y.; Liu, Y.; Li, G.

2018-01-01

Objectives As one of the heat-stable enterotoxins, Staphylococcal enterotoxin C2 (SEC2) is synthesized by Staphylococcus aureus, which has been proved to inhibit the growth of tumour cells, and is used as an antitumour agent in cancer immunotherapy. Although SEC2 has been reported to promote osteogenic differentiation of human mesenchymal stem cells (MSCs), the in vivo function of SCE2 in animal model remains elusive. The aim of this study was to further elucidate the in vivo effect of SCE2 on fracture healing. Materials and Methods Rat MSCs were used to test the effects of SEC2 on their proliferation and osteogenic differentiation potentials. A rat femoral fracture model was used to examine the effect of local administration of SEC2 on fracture healing using radiographic analyses, micro-CT analyses, biomechanical testing, and histological analyses. Results While SEC2 was found to have no effect on rat MSCs proliferation, it promoted the osteoblast differentiation of rat MSCs. In the rat femoral fracture model, the local administration of SEC2 accelerated fracture healing by increasing fracture callus volumes, bone volume over total volume (BV/TV), and biomechanical recovery. The SEC2 treatment group has superior histological appearance compared with the control group. Conclusion These data suggest that local administration of SEC2 may be a novel therapeutic approach to enhancing bone repair such as fracture healing. Cite this article: T. Wu, J. Zhang, B. Wang, Y. Sun, Y. Liu, G. Li. Staphylococcal enterotoxin C2 promotes osteogenesis of mesenchymal stem cells and accelerates fracture healing. Bone Joint Res 2018;7:179–186. DOI: 10.1302/2046-3758.72.BJR-2017-0229.R1. PMID:29682284

MeT-DB V2.0: elucidating context-specific functions of N6-methyl-adenosine methyltranscriptome

PubMed Central

Liu, Hui; Wang, Huaizhi; Wei, Zhen; Zhang, Songyao; Hua, Gang; Zhang, Shao-Wu; Zhang, Lin; Gao, Shou-Jiang

2018-01-01

Abstract Methyltranscriptome is an exciting new area that studies the mechanisms and functions of methylation in transcripts. A knowledge base with the systematic collection and curation of context specific transcriptome-wide methylations is critical for elucidating their biological functions as well as for developing bioinformatics tools. Since its inception in 2014, the Met-DB (Liu, H., Flores, M.A., Meng, J., Zhang, L., Zhao, X., Rao, M.K., Chen, Y. and Huang, Y. (2015) MeT-DB: a database of transcriptome methylation in mammalian cells. Nucleic Acids Res., 43, D197–D203), has become an important resource for methyltranscriptome, especially in the N6-methyl-adenosine (m6A) research community. Here, we report Met-DB v2.0, the significantly improved second version of Met-DB, which is entirely redesigned to focus more on elucidating context-specific m6A functions. Met-DB v2.0 has a major increase in context-specific m6A peaks and single-base sites predicted from 185 samples for 7 species from 26 independent studies. Moreover, it is also integrated with a new database for targets of m6A readers, erasers and writers and expanded with more collections of functional data. The redesigned Met-DB v2.0 web interface and genome browser provide more friendly, powerful, and informative ways to query and visualize the data. More importantly, MeT-DB v2.0 offers for the first time a series of tools specifically designed for understanding m6A functions. Met-DB V2.0 will be a valuable resource for m6A methyltranscriptome research. The Met-DB V2.0 database is available at http://compgenomics.utsa.edu/MeTDB/ and http://www.xjtlu.edu.cn/metdb2. PMID:29126312

Yi min Zhang | NREL

Science.gov Websites

Volkswagen Automotive Company, Ltd. Shanghai, China (1990-1996) Featured Publications Vimmerstedt, L., A . NREL/JA-5100-61691. doi:10.1002/bbb.1434 Chum, H. L., Y. Zhang, J. Hill, D.G. Tiffany, R.V. Morey, A.G -60059. Warner, E., D. Inman, B. Kunstman, B. Bush, L. Vimmerstedt, S. Peterson, J. Macknick, and Y

Description of two new species of the Neoperla montivaga group (Plecoptera: Perlidae) from Guangxi Zhuang Autonomous Region, China.

PubMed

Yang, Juan; Zhang, Sujiong; Li, Weihai

2017-03-05

The following two new species from Shiwandashan of Guangxi Zhuang Autonomous Region, China are described, Neoperla bicolor Yang, Zhang & Li, sp. nov. and N. muranyii Yang, Zhang & Li, sp. nov. The new species are compared with related congeners of their respective species subgroups.

Targeting the I-Kappa-B Kinase Epsilon (IKKe) for Breast Cancer Therapy

DTIC Science & Technology

2009-09-01

Mol Pharm 2009, 6(3):772-779. 15. Cheng K, Fraga D, Zhang C, Kotb M, Gaber AO, Guntaka RV, Mahato RI: Adenovirus-based vascular endothelial growth...Pharmaceutics 2009, 6, 772– 779. (27) Cheng, K.; Fraga, D.; Zhang, C.; Kotb, M.; Gaber , A. O.; Guntaka, R. V.; Mahato, R. I. Adenovirus-based vascular

Reader reaction to "a robust method for estimating optimal treatment regimes" by Zhang et al. (2012).

PubMed

Taylor, Jeremy M G; Cheng, Wenting; Foster, Jared C

2015-03-01

A recent article (Zhang et al., 2012, Biometrics 168, 1010-1018) compares regression based and inverse probability based methods of estimating an optimal treatment regime and shows for a small number of covariates that inverse probability weighted methods are more robust to model misspecification than regression methods. We demonstrate that using models that fit the data better reduces the concern about non-robustness for the regression methods. We extend the simulation study of Zhang et al. (2012, Biometrics 168, 1010-1018), also considering the situation of a larger number of covariates, and show that incorporating random forests into both regression and inverse probability weighted based methods improves their properties. © 2014, The International Biometric Society.

Comment on "exact solutions of the derivative nonlinear Schrödinger equation for a nonlinear transmission line".

PubMed

Nickel, J; Schürmann, H W

2007-03-01

In a recent article Kengne and Liu [Phys. Rev. E 73, 026603 (2006)] have presented a number of exact elliptic solutions for a derivative nonlinear Schrödinger equation. It is the aim of this Comment to point out that all these solutions given in Secs. II and III of this article (referred to as KL in the following) are subcases of the general solution of Eq. (KL.9). Conditions for the parameters A-E of the solutions given by Kengne and Liu can be found from general conditions for solitary and periodic elliptic solutions as shown in the following. Positive and bounded solutions can be found by considering the phase diagram. Therefore, the comment of Kengne and Liu that "we find its particular positive bounded solutions" can be specified.

Application of the Hughes-LIU algorithm to the 2-dimensional heat equation

NASA Technical Reports Server (NTRS)

Malkus, D. S.; Reichmann, P. I.; Haftka, R. T.

1982-01-01

An implicit explicit algorithm for the solution of transient problems in structural dynamics is described. The method involved dividing the finite elements into implicit and explicit groups while automatically satisfying the conditions. This algorithm is applied to the solution of the linear, transient, two dimensional heat equation subject to an initial condition derived from the soluton of a steady state problem over an L-shaped region made up of a good conductor and an insulating material. Using the IIT/PRIME computer with virtual memory, a FORTRAN computer program code was developed to make accuracy, stability, and cost comparisons among the fully explicit Euler, the Hughes-Liu, and the fully implicit Crank-Nicholson algorithms. The Hughes-Liu claim that the explicit group governs the stability of the entire region while maintaining the unconditional stability of the implicit group is illustrated.

China Report, Science and Technology, No. 186

DTIC Science & Technology

1983-02-03

AUTOMOBILE TECHNOLOGY QICHE JISHU [AUTOMOBILE TECHNOLOGY] No 10, 25 Oct 82 .................. 20 GEOLOGY TONGJI DAXUE XUEBAO [JOURNAL OF TONGJI UNIVERSITY...33 - b - APPLIED SCIENCES HEBEI’S LIU BINGYAN ON IMPORTING TECHNOLOGY HK040452 Beijing ZHONGGUO XINWEN SHE in Chinese 1127 GMT 3 Dec 82...Text] Beijing , 3 Dec (ZHONGGUO XINWEN SHE)--People’s deputy and Hebei pro- vincial acting Governor Liu Bingyan said at an NPC discussion meeting on 2

High performance gas adsorption and separation of natural gas in two microporous metal-organic frameworks with ternary building units.

PubMed

Wang, Dongmei; Zhao, Tingting; Cao, Yu; Yao, Shuo; Li, Guanghua; Huo, Qisheng; Liu, Yunling

2014-08-14

Two novel MMOFs, JLU-Liu5 and JLU-Liu6, are based on ternary building units and exhibit high adsorption selectivity for CO2, C2H6 and C3H8 over CH4, which is attributed to steric effects and host-guest interactions. These MMOFs are promising materials for gas adsorption and natural gas purification.

Multimodality Image-Guided HDR/IMRT in Prostate Cancer: Combined Molecular Targeting Using Nanoparticle MR, 3D MRSI, and 11C Acetate PET Imaging

DTIC Science & Technology

2005-08-01

Ph.D. Panos Fatouros, Ph.D. Jerry Hirsch, MSc, PharmD Rhonda Hoyle Kristin Schmidt Dorin Tudor, Ph.D. Jie Liu CONTRACTING ORGANIZATION: Virginia...McClish, Ph.D., Panos Fatouros, Ph.D., Jerry Hirsch, MSc, PharmD, 5e. TASK NUMBER Rhonda Hoyle, Kristin Schmidt, Dorin Tudor, Ph.D., Jie Liu 5f. WORK UNIT

Making Aggressive Prostate Cancer Quiescent by Abrogating Cholesterol Esterification

DTIC Science & Technology

2016-10-01

team has been assembled , with expertise in spectroscopic imaging & nanomedicine (Dr. J. X. Cheng, PI), biochemistry (Dr. X. Liu, co-PI), and prostate...was approved in 2004 as the first- line cytotoxic chemotherapy owing to a modest increase in overall survival compared to mitoxantrone. Since 2010...interdisciplinary research team has been assembled , with expertise in spectroscopic imaging & nanomedicine (Dr. J. X. Cheng, PI), biochemistry (Dr. X. Liu, co-PI

In situ Raman Spectroscopy Study of the Formation of Graphene from Urea and Graphite Oxide

DTIC Science & Technology

2012-09-01

pp. 075404, Aug., 2006. [5] K. S. Novoselov, Z. Jiang, Y. Zhang, S. Morozov, H. Stormer , U. Zeitler, J. Maan, G. Boebinger, P. Kim, and A. Geim...Room-temperature quantum hall effect in graphene.” Science, vol. 315, no. 5817, pp. 1379, Mar., 2007. [6] Y. Zhang, Y. W. Tan, H. L. Stormer , and

Renewable Bio-Solar Hydrogen Production: The Second Generation (Part B)

DTIC Science & Technology

2015-03-20

SUBJECT TERMS Biohydrogen, biofuels, cyanobacteria, photosynthesis, fermentation , transcription profiling, metabolic engineering, TCA cycle... fermentation in the cyanobacterium Arthrospira (Spirulina) maxima CS-328. Appl. Environ. Microbiol., 77: 7185-7194. 5. Zhang, S. and Bryant, D. A...glycogen is the preferred substrate during auto- fermentation . J. Biotech. 166: 65-75. 10. Kumaraswamy, G. K., Guerra, T., Qian, X., Zhang, S., Bryant

Division by zero, pseudo-division by zero, Zhang dynamics method and Zhang-gradient method about control singularity conquering

NASA Astrophysics Data System (ADS)

Zhang, Yunong; Zhang, Yinyan; Chen, Dechao; Xiao, Zhengli; Yan, Xiaogang

2017-01-01

In this paper, the division-by-zero (DBO) problem in the field of nonlinear control, which is traditionally termed the control singularity problem (or specifically, controller singularity problem), is investigated by the Zhang dynamics (ZD) method and the Zhang-gradient (ZG) method. According to the impact of the DBO problem on the state variables of the controlled nonlinear system, the concepts of the pseudo-DBO problem and the true-DBO problem are proposed in this paper, which provide a new perspective for the researchers on the DBO problems as well as nonlinear control systems. Besides, the two classes of DBO problems are solved under the framework of the ZG method. Specific examples are shown and investigated in this paper to illustrate the two proposed concepts and the efficacy of the ZG method in conquering pseudo-DBO and true-DBO problems. The application of the ZG method to the tracking control of a two-wheeled mobile robot further substantiates the effectiveness of the ZG method. In addition, the ZG method is successfully applied to the tracking control of a pure-feedback nonlinear system.

Development of a Native Fractionation Antigen Microarray for Autoantibody Profiling in Breast Cancer

DTIC Science & Technology

2011-10-01

Antigen Microarray for Autoantibody Profiling in Breast Cancer PRINCIPAL INVESTIGATOR: Brian C.-S. Liu, Ph.D...Profiling in Breast Cancer 5b. GRANT NUMBER W81XWH-09-1-0684 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Brian C.-S. Liu...NOTES 14. ABSTRACT The humoral response of a cancer patient may allow earlier detection of cancer than current methods allow. If so, the serum

Aeronautical Materials (Selected Articles),

DTIC Science & Technology

1984-03-13

directional technique. We would like to deeply thank comrades Dong Yuzhuo, Liu Nianqing, Yuan Pinzhen, Sun Shuzhen, Li Shuhuan etc. and other fraternal units...1Burton, C.J7., "Superalloys, Metallurgy and -Manufacture", Li 1976, p14 7. P [3 1Cai Julin and Zheng Yunrong, "A Study of the Interdend- ritic...of the Beijing Institute of Aeronautical Materials, Liu Ansheng and Li Yonghong of the General Academy of Nonferrous Metals, Yang Yanhua of the Coal

Entanglement criterion for tripartite systems based on local sum uncertainty relations

NASA Astrophysics Data System (ADS)

Akbari-Kourbolagh, Y.; Azhdargalam, M.

2018-04-01

We propose a sufficient criterion for the entanglement of tripartite systems based on local sum uncertainty relations for arbitrarily chosen observables of subsystems. This criterion generalizes the tighter criterion for bipartite systems introduced by Zhang et al. [C.-J. Zhang, H. Nha, Y.-S. Zhang, and G.-C. Guo, Phys. Rev. A 81, 012324 (2010), 10.1103/PhysRevA.81.012324] and can be used for both discrete- and continuous-variable systems. It enables us to detect the entanglement of quantum states without having a complete knowledge of them. Its utility is illustrated by some examples of three-qubit, qutrit-qutrit-qubit, and three-mode Gaussian states. It is found that, in comparison with other criteria, this criterion is able to detect some three-qubit bound entangled states more efficiently.

Electronic Struture and Quantum Effects of Thin Metal Film Systems Based on Silicon Carbide

DTIC Science & Technology

2013-05-01

324, 924 (2009). [33] K. S. Novoselov et al., Nature (London) 438, 197 (2005). [34] Y. Zhang, Y.-W. Tan, H. L. Stormer , and P. Kim, Nature (London...Zhang, Y.-W. Tan, H. L. Stormer , and P. Kim, Nature (London) 438, 201 (2005). [6] K. S. Novoselov et al., Nature Phys. 2, 177 (2006). [7] E. McCann and V

Finite-element modeling of soft tissue rolling indentation.

PubMed

Sangpradit, Kiattisak; Liu, Hongbin; Dasgupta, Prokar; Althoefer, Kaspar; Seneviratne, Lakmal D

2011-12-01

We describe a finite-element (FE) model for simulating wheel-rolling tissue deformations using a rolling FE model (RFEM). A wheeled probe performing rolling tissue indentation has proven to be a promising approach for compensating for the loss of haptic and tactile feedback experienced during robotic-assisted minimally invasive surgery (H. Liu, D. P. Noonan, B. J. Challacombe, P. Dasgupta, L. D. Seneviratne, and K. Althoefer, "Rolling mechanical imaging for tissue abnormality localization during minimally invasive surgery, " IEEE Trans. Biomed. Eng., vol. 57, no. 2, pp. 404-414, Feb. 2010; K. Sangpradit, H. Liu, L. Seneviratne, and K. Althoefer, "Tissue identification using inverse finite element analysis of rolling indentation," in Proc. IEEE Int. Conf. Robot. Autom. , Kobe, Japan, 2009, pp. 1250-1255; H. Liu, D. Noonan, K. Althoefer, and L. Seneviratne, "The rolling approach for soft tissue modeling and mechanical imaging during robot-assisted minimally invasive surgery," in Proc. IEEE Int. Conf. Robot. Autom., May 2008, pp. 845-850; H. Liu, P. Puangmali, D. Zbyszewski, O. Elhage, P. Dasgupta, J. S. Dai, L. Seneviratne, and K. Althoefer, "An indentation depth-force sensing wheeled probe for abnormality identification during minimally invasive surgery," Proc. Inst. Mech. Eng., H, vol. 224, no. 6, pp. 751-63, 2010; D. Noonan, H. Liu, Y. Zweiri, K. Althoefer, and L. Seneviratne, "A dual-function wheeled probe for tissue viscoelastic property identification during minimally invasive surgery," in Proc. IEEE Int. Conf. Robot. Autom. , 2008, pp. 2629-2634; H. Liu, J. Li, Q. I. Poon, L. D. Seneviratne, and K. Althoefer, "Miniaturized force indentation-depth sensor for tissue abnormality identification," IEEE Int. Conf. Robot. Autom., May 2010, pp. 3654-3659). A sound understanding of wheel-tissue rolling interaction dynamics will facilitate the evaluation of signals from rolling indentation. In this paper, we model the dynamic interactions between a wheeled probe and a soft tissue sample using the ABAQUS FE software package. The aim of this work is to more precisely locate abnormalities within soft tissue organs using RFEM and hence aid surgeons to improve diagnostic ability. The soft tissue is modeled as a nonlinear hyperelastic material with geometrical nonlinearity. The proposed RFEM was validated on a silicone phantom and a porcine kidney sample. The results show that the proposed method can predict the wheel-tissue interaction forces of rolling indentation with good accuracy and can also accurately identify the location and depth of simulated tumors.

A Genome-wide Breast Cancer Scan in African Americans

DTIC Science & Technology

2012-06-01

Vuorinen A, Kaaks R, Ko YD, Kolonel LN, Konstantopoulou I, Kosma VM, Kulkarni S, Lambrechts D, Lee AM, Marchand LL, Lesnick T, Liu J, Lindstrom S...Mannermaa A, Margolin S, Martin NG, Miron P, Montgomery GW, Nevanlinna H, Nickels S, Nyante S, Olswold C, Palmer J, Pathak H, Pectasides D, Perou CM...Vuorinen A, Kaaks R, Ko YD, Kolonel LN, Konstantopoulou I, Kosma VM, Kulkarni S, Lambrechts D, Lee AM, Marchand LL, Lesnick T, Liu J, Lindstrom S

Achieving Alignment: An Analysis of Enterprise Architecture Best Practices within the United States Air Force

DTIC Science & Technology

2009-03-01

Overview In this chapter, a literature review is conducted relevant to the research topics found to contribute to the successful creation and...priorities, and any common IT standards and tools ( Armour , Kaisler, and Liu 1999b). The vision defines the business strategy of the organization...and depicts how the enterprise will use IT in support of that strategy ( Armour , Kaisler, and Liu 1999a). One method of selecting this vision

Notes on the Stenus cirrus group of Zhejiang, East China, with descriptions of two new species (Coleoptera, Staphylinidae).

PubMed

Liu, Sheng-Nan; Tang, Liang; Luo, Rong-Ting

2017-01-01

Two new Stenus species of the cirrus group collected from Zhejiang Province, East China, are described, S. wuyanlingus Liu, Tang & Luo, sp. n. , S. yuyimingi Liu, Tang & Luo, sp. n. and a new distributional locality for S. ovalis Tang, Li & Zhao, 2005 was discovered. The diagnostic characters of the new species are illustrated, and a key to species of the group from Zhejiang Province is provided.

Planned experiments and corpus based research play a complementary role. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Vasishth, Shravan

2017-07-01

This interesting and informative review by Liu and colleagues [17] in this issue covers the full spectrum of research on the idea that in natural language, dependency distance tends to be small. The authors discuss two distinct research threads: experimental work from psycholinguistics on online processes in comprehension and production, and text-corpus studies of dependency length distributions.

Notes on the Stenus cirrus group of Zhejiang, East China, with descriptions of two new species (Coleoptera, Staphylinidae)

PubMed Central

Liu, Sheng-Nan; Tang, Liang; Luo, Rong-Ting

2017-01-01

Abstract Two new Stenus species of the cirrus group collected from Zhejiang Province, East China, are described, S. wuyanlingus Liu, Tang & Luo, sp. n., S. yuyimingi Liu, Tang & Luo, sp. n. and a new distributional locality for S. ovalis Tang, Li & Zhao, 2005 was discovered. The diagnostic characters of the new species are illustrated, and a key to species of the group from Zhejiang Province is provided. PMID:28769734

Diet Composition Exacerbrates or Attenuates Soman Toxicity in Rats: Implied Metabolic Control of Nerve Agent Toxicity

DTIC Science & Technology

2011-01-01

elevated sugar intake (glucose or high fructose corn syrup in drinking water) exacerbates the toxicity of parathion poisoning, an organophos- phorus...OP) insecticide (Liu et al., 2005, 2007; Olivier et al., 2001). In Liu et al. (2005), adult rats that had consumed high fructose corn syrup in...exacerbated toxicity of the OP pesticide parathion in rats given drinking water with high fructose corn syrup or glucose added. Furthermore, deldrin

Aligned Carbon Nanotube Carpets on Carbon Substrates for High Power Electronic Applications

DTIC Science & Technology

2016-06-01

SiOx by a vapor-solid-solid mechanism ,” J. Am. Chem. Soc., vol. 133, pp. 197–199, 2011. [146] B. Liu, W. Ren, C. Liu, C.-H. Sun , L. Gao, S. Li, C... Mechanical and Thermal Systems Branch Power and Control Division JUNE 2016 Interim Report DISTRIBUTION STATEMENT A: Approved for public release...Advisor Program Engineer Mechanical and Thermal Systems Branch Mechanical and Thermal Systems Branch Power and Control Division Power and Control

[Learning experience of acupuncture technique from professor ZHANG Jin].

PubMed

Xue, Hongsheng; Zhang, Jin

2017-08-12

As a famous acupuncturist in the world, professor ZHANG Jin believes the key of acupuncture technique is the use of force, and the understanding of the "concentrating the force into needle body" is essential to understand the essence of acupuncture technique. With deep study of Huangdi Neijing ( The Inner Canon of Huangdi ) and Zhenjiu Dacheng ( Compendium of Acupuncture and Moxibustion ), the author further learned professor ZHANG Jin 's theory and operation specification of "concentrating force into needle body, so the force arriving before and together with needle". The whole-body force should be subtly focused on the tip of needle, and gentle force at tip of needle could get significant reinforcing and reducing effect. In addition, proper timing at tip of needle could start reinforcing and reducing effect, lead qi to disease location, and achieve superior clinical efficacy.

Integrating Asian Film into Film Studies and Film Production Courses Using Examples from Yasujiro Ozu (Japan) and Zhang Yimou (China). Asian Studies Module, 1997.

ERIC Educational Resources Information Center

Carson, Diane

This curriculum module offers concrete and specific examples for instructors who wish to integrate the films of Yasujiro Ozu of Japan and Zhang Yimou from China into film studies courses. Through this module, students should learn to compare and contrast conventional screen space, color, and editing to alternative forms. By becoming more familiar…

Current Chinese Leadership Update

DTIC Science & Technology

1985-08-01

Horst Soelle fontacts East German Minister for the Construction of Heavy Machinery and Equipment Rolf Kersten 6 Contacts East German Deputy Minister for...Minister for Defense for Procurement Adam Butler Ana_1sis Commander of the CPLA Air Force Zhang Tingfa visited 9 France (29 May-9 June 1985) and the...Chief Marshal Sir Keith Williamson, MinisteL of Defense for Procurement Adam Butler, and other unidentified British military officials. Zhang visited

The Relationship of Goldberg's Big Five Personality Trait Measures of Mid-Level Leaders at Midwest State-Supported Colleges and Universities to the Cameron and Quinn Competing Values Model

ERIC Educational Resources Information Center

Kempke Eppler, Michelle R.

2012-01-01

This dissertation expands previous work of Giberson, Resick, Dickson, Mitchelson, Randall, and Clark (2009), Zhang, Tsui, Song, & Jia (2008), and Tsui, Zhang, Wang, Xin, and Wu (2006) by examining higher education organizational culture and leadership. There is a paucity of research in examining the relationships between university mid-level…

Capturing Parent-Child Interactions With Social Media: Comment on Zhang et al. (2015).

PubMed

Leung, Ricky; Dong, Guanghui; Qin, Xiaoxia; Lin, Shao

2016-06-01

Zhang et al. conducted a qualitative study of children presented with 19 parental structuring behaviors of parental control and were asked to attribute the parent's intent behind the behaviors. The authors developed several conceptual categories, "parent-centered," "child-centered," or "social" interests. Here, we describe how their 12 propositions could be empirically tested in further studies using social media. © The Author(s) 2016.

[A Chinese Philosophical Foundation for the Sacred Mission of Nurses: The Ways of Heaven and Life are Correlated].

PubMed

Lee, Mei-Hsiu

2016-08-01

Clinical nursing practice uses professional nursing techniques, empathy, and moral judgment to help relieve the pain of patients who are suffering physically or mentally from trauma or illness. Thus, nursing involves sacred tasks. According to Confucian reasoning, morality is expressed through everyday actions. Providing care to patients arouses concern and sympathy in the caregiver, which induces him or her to fully apply professional knowledge to this task. This conduct demonstrates the moral conscience of nurses. The Chinese adage "Tian-tao hsing-ming hsiang kuan tung" (the way of heaven and life are correlated), attributed to Northern Song dynasty scholar Zhang Tsai, aptly explains the sacred mission of the nursing profession. Zhang held that all humans are born with a conscience that is given by heaven. However, human senses and desires may suppress this conscience. As Zhang Tsai suggested, the conscience must be cultivated in order to be manifested. The increase in recent years of international academic discussion / research related to the value and meaning of nursing and of exploration into how to promote the moral competence of nurses, not only provide support to Zhang's argument that "tian-tao" and "hsing-ming" are correlated but also provide positive momentum toward enhancing the self-worth of nurses and enabling patients to receive better care.

Efficiency and Pressure Loss Characteristics of an Ultra-Compact Combustor with Bulk Swirl

DTIC Science & Technology

2007-06-01

al., 2004a:3). Besides offering size and weight reductions, the UCC opens the door to adding a reheat step to the Brayton cycle currently used in...possible include a reheat step in the Brayton cycle to gain enhanced performance. Sirignano and Liu (Sirignano and Liu, 1998:1-2) pioneered the idea of...increase in speed for a subsonic flow resulting in a given loss in total pressure. This pressure loss is not desired in the constant pressure Brayton

Dependency distance: A new perspective on the syntactic development in second language acquisition. Comment on "Dependency distance: A new perspective on syntactic patterns in natural language" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Jiang, Jingyang; Ouyang, Jinghui

2017-07-01

Liu et al. [1] offers a clear and informative account of the use of dependency distance in studying natural languages, with a focus on the viewpoint that dependency distance minimization (DDM) can be regarded as a linguistic universal. We would like to add the perspective of employing dependency distance in the studies of second languages acquisition (SLA), particularly the studies of syntactic development.

Investigation of Optical Fibers for Coherent Anti-Stokes Raman Scattering (CARS) Spectroscopy in Reacting Flows (Postprint)

DTIC Science & Technology

2012-03-01

applications. Springer, Netherlands Pronko PP, VanRompay PA, Horvath C, Loesel F, Juhasz T, Liu X, Mourou G (1998) Avalanche ionization and dielectric Exp...Birks TA, Russell PSJ, Roberts PJ, Allan DC (1999) Single-mode photonic band gap guidance of light in air. Science 285:1537–1539 Du D, Liu X, Mourou G ...Lowdermilk WH, Milam D (1984) Review of ultraviolet damage threshold measurements at Lawrence Livemore National Labo- ratory. Proc SPIE 476:143–162 Mann G

Cytokine Disruption to Prevent Radiation Related Breast Damage

DTIC Science & Technology

2006-09-01

CA11051-30 and ACS RSC-01-071-01 PRP. REFERENCES 1. M. Amichetti, L. Busana and O. Callo, Long-term cosmetic outcome and toxicity in patients treated with...25), 11874-11878 (1995). 37. W. Liu, Y. Chen, W. Wang, P. Keng, J. Finkelstein, B. Fenton , P. Okunieff and I. Ding, Combination of radiation and...celebrex reduces mammary and lung tumor growth. Am. J. Clin. Oncol. 26, S103-S109 (2003). 38. I. Ding, J. Sun, B. Fenton , W. Liu, P. Kimsely, P. Okunieff

Therapeutic Role of Bmi-1 Inhibitors in Eliminating Prostate Tumor Stem Cells

DTIC Science & Technology

2014-10-01

Res 62:4736-45, (2002). PMC: 12183433. 14. Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, Suri P, Wicha MS. Hedgehog signaling and Bmi-1...Among these interacting pathways are BMI-1, OCT3/4, Hedgehog (Hh), Wnt/β-catenin, Notch signaling, Hox gene family, PTEN/Akt pathway, efflux...cancer, and cancer stem cells. Nature 414, 105-111 (2001). 50. Liu, S., et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and

Evaluation of Acid Ceramidase Overexpression-Induced Activation of the Oncogenic Akt Pathway in Prostate Cancer

DTIC Science & Technology

2014-01-01

Marrison, S.T., Norris , J.S., and Liu, X. 2013. Acid Ceramidase Promotes Nuclear Export of PTEN through Sphingosine 1-Phosphate Mediated Akt...cancer. Genes Chromo- somes Cancer 2000; 29: 137–146. 2 Norris JS, Bielawska A, Day T, El-Zawahri A, Elojeimy S, Hannun Y et al. Combined therapeutic use...Joseph C. Cheng, Ping Lu, S. Tucker Marrison, James S. Norris , Xiang Liu Department of Microbiology and Immunology, Medical University of South Carolina

Beyond description. Comment on "Approaching human language with complex networks" by Cong and Liu

NASA Astrophysics Data System (ADS)

Ferrer-i-Cancho, R.

2014-12-01

In their historical overview, Cong & Liu highlight Sausurre as the father of modern linguistics [1]. They apparently miss G.K. Zipf as a pioneer of the view of language as a complex system. His idea of a balance between unification and diversification forces in the organization of natural systems, e.g., vocabularies [2], can be seen as a precursor of the view of complexity as a balance between order (unification) and disorder (diversification) near the edge of chaos [3]. Although not mentioned by Cong & Liu somewhere else, trade-offs between hearer and speaker needs are very important in Zipf's view, which has inspired research on the optimal networks mapping words into meanings [4-6]. Quantitative linguists regard G.K. Zipf as the funder of modern quantitative linguistics [7], a discipline where statistics plays a central role as in network science. Interestingly, that centrality of statistics is missing Saussure's work and that of many of his successors.

Stakeholders Opinions on Multi-Use Deep Water Offshore Platform in Hsiao-Liu-Chiu, Taiwan

PubMed Central

Sie, Ya-Tsune; Chang, Yang-Chi; Lu, Shiau-Yun

2018-01-01

This paper describes a group model building activity designed to elicit the potential effects a projected multi-use deep water offshore platform may have on its local environment, including ecological and socio-economic issues. As such a platform is proposed for construction around the island of Hsiao-Liu-Chiu, Taiwan, we organized several meetings with the local stakeholders and structured the debates using group modeling methods to promote consensus. During the process, the participants iteratively built and revised a causal-loop diagram that summarizes their opinions. Overall, local stakeholders concluded that a multi-use deep water offshore marine platform might have beneficial effects for Hsiao-Liu-Chiu because more tourists and fish could be attracted by the structure, but they also raised some potential problems regarding the law in Taiwan and the design of the offshore platform, especially its resistance to extreme weather. We report the method used and the main results and insights gained during the process. PMID:29415521

Review of the genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae) with description of two new species.

PubMed

Chang, Zhi-Min; Yang, Lin; Zhang, Zheng-Guang; Chen, Xiang-Sheng

2015-12-11

Two new species of the issid genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae): Neotetricodes longispinus Chang et Chen sp. nov. (China: Yunnan) and Neotetricodes xiphoideus Chang et Chen sp. nov. (China: Yunnan) are described and illustrated. The generic characteristic is redefined. A checklist and key to the species of the genus are provided. The female genitalia of the genus are firstly described.

China Report, Political, Sociological and Military Affairs

DTIC Science & Technology

1985-02-05

away long ago. However, their in- domitable spirit and their spirit of heroic struggle are still fresh in my memory. At that time, Cao Rui, the... Cao Rui were compelled to solve the problem through legal means by transferring the representatives in custody to the Hebei Provincial Court of...Zhang Ming, Tang Shudi, Want Zibo, Wang Jingmin, Li Baoqi. Wei Jinshan, and Chen Hui: advisers of the military region Sun Keji, Zhang Yuhua , and Wu

Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer

DTIC Science & Technology

2006-07-01

TumorCells Qiang Zhang,1 Thomas L. Jang,1 Ximing Yang,2 Irwin Park,1 Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4...reactive CD8+ T cells activates the antitumor immune response cycle Qiang Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic

JPRS Report, China

DTIC Science & Technology

1989-06-14

Wensheng are still single and unmarried . Zhang Hanzhi [4545 0698 0037], the third woman in this group, came from a well-known family. Her father, Zhang...also a "senior translator" originally, who later married Qiao Guanhua [0829 0385 5478]. The Background for Criticizing Lin [Biao], Confucius, and...hopes on reform of the ownership system instead. But can the problem of millions who have jobs but are "unem- ployed" and millions who are still

Materials and Mechanics of Metamaterial Enhanced MEMS for Terahertz Technology

DTIC Science & Technology

2013-12-23

raveritt@physics.bu.edu Major Ph.D. students who have worked on this project: Hu Tao, Kebin Fan, Huseyin Seren Major postdoctoral researchers who have...please contact Prof. Xin Zhang at the address given above. DISTRIBUTION A: Distribution approved for public release. 2 Huseyin Seren will...Title: Optically Tunable Terahertz Metamaterials on Highly Flexible Substrates * With K. Fan, X. Zhao, J. Zhang, G.R. Keiser, H.R. Seren , G.D. Metcalfe

Optical High Harmonic Generation in C60

NASA Astrophysics Data System (ADS)

Zhang, Guoping

2005-03-01

C60 et al. Physical Review Letters Physical Review B High harmonic generation (HHG) requires a strong laser field, but in a relatively weak laser field is sufficient. Numerical results presented here show while its low order harmonics result from the laser field, its high order ones are mainly from the multiple excitations. Since high order harmonics directly correlate electronic transitions, the HHG spectrum accurately measures transition energies. Therefore, is not only a promising material for HHG, but may also present an opportunity to develop HHG into an electronic structure probing tool. References: G. P. Zhang, 91, 176801 (2003); G. P. Zhang and T. F. George, 68, 165410 (2003); P. B. Corkum, 71, 1994 (1993); G. P. Zhang and Thomas F. George, 93, 147401 (2004); H. Niikura ,ature 417, 917 (2002); ibid. 421, 826 (2003); Y. Mairesse ,cience 302, 1540 (2003); A. Baltuska ,ature 421, 611 (2003).

Long-range temporal correlations in the Kardar-Parisi-Zhang growth: numerical simulations

NASA Astrophysics Data System (ADS)

Song, Tianshu; Xia, Hui

2016-11-01

To analyze long-range temporal correlations in surface growth, we study numerically the (1  +  1)-dimensional Kardar-Parisi-Zhang (KPZ) equation driven by temporally correlated noise, and obtain the scaling exponents based on two different numerical methods. Our simulations show that the numerical results are in good agreement with the dynamic renormalization group (DRG) predictions, and are also consistent with the simulation results of the ballistic deposition (BD) model.

Ionospheric Characteristics for Archiving at the World Data Centers

DTIC Science & Technology

1990-12-01

for the application and programs written to generate these database files using as input Digisonde 256 ARTIST [Reinisch and Huang, 1983; Reinisch et al...1983; Tang et al., 19891 data, post processed by the ULCAR ADEP [Zhang, 1989; Zhang et al., 19881 ( ARTIST Data Editing Program) system. The...Digisonde ARTIST [Tang et al. 19891. FORTRAN records i+lI to k give the Dimensions corresponding to the characteristics list (see 3 Table 2), these are in

Mechanisms of alpha-Synuclein Aggregation and Toxicity

DTIC Science & Technology

2006-09-01

Zhang, P. St George- [36] Y . Zhang, J. Gao, K.K. Chung, H. Huang, V.L. Dawson, T.M. Hyslop , Mutation of the conserved N-terminal cysteine (Cys92) of...pathies. The incidence of NFTs in Parkinson’s disease is much greater than in an age-matched population (Boller et al., 1980 ). Tau-immunoreactive Lewy...nervous system. J. Cell Biol. 101, 1371–1378. Boller, F., Mizutani, T., Roessmann, U., Gambetti, P., 1980 . Parkinson disease, dementia, and Alzheimer

Electronic structure of antifluorite Cu2X (X = S, Se, Te) within the modified Becke-Johnson potential plus an on-site Coulomb U.

PubMed

Zhang, Yubo; Wang, Youwei; Xi, Lili; Qiu, Ruihao; Shi, Xun; Zhang, Peihong; Zhang, Wenqing

2014-02-21

The traditional photon absorbers Cu2-xX (X = S, Se, and Te) have regained significant research attention in the search of earth-abundant photovoltaic materials. These moderate- and narrow-gap materials have also been shown to exhibit excellent thermoelectric properties recently. However, semimetallic band structures with inverted band orderings are predicted for antifluorite structure Cu2X using density functional theory with the local density approximation or the generalized gradient approximation. We find that semiconducting band structures and normal band orderings can be obtained using the modified Becke-Johnson potential plus an on-site Coulomb U (the mBJ+U approach), which is consistent with our earlier finding for diamond-like Cu-based multinary semiconductors [Y. Zhang, J. Zhang, W. Gao, T. A. Abtew, Y. Wang, P. Zhang, and W. Zhang, J. Chem. Phys. 139, 184706 (2013)]. The trend of the chemical bonding of Cu2X is analyzed, which shows that the positions of the valence band maximum and conduction band minimum are strongly affected by the inter-site pd and intra-site sp hybridizations, respectively. The calculated gaps of Cu2S and Cu2Se still seem to be underestimated compared with experimental results. We also discuss the effects of different structural phases and Cu disordering and deficiency on the bandgaps of these materials.

A Biographical Approach to Chinese Political Analysis

DTIC Science & Technology

1975-10-01

Liu Po-ch’eng Chang Kuo -t ’ao Ch’en I Su Yll Lin Piao Nieh Jung -chen Sources: William Whitson, "The Field Army in Chinese Communist Military...since 1954 Founders 1, 2, 3, 5, 6 Ho Lung 12, 13, 14, 15, HeU Haiang-ch’ien 16, 18, 60 (in Liu Po-ch ’eng Szechwan), 61, 62 Chang Kuo -t’ ao 20...66, 67. 68 Nieh Jung -chen Sources: William Whitson, "The Field Army in Chinese Communist Military Politics," The China Quarterly, No, 37, Januar y

Translations From Red Flag, Number 6, 3 June 1978

DTIC Science & Technology

1978-08-07

Control of Population Growth (pp 60-64) (Liu Jo-ching) • 106 Planned Economy and the Law of Value (pp 65-70) (Liu Kuo -kuang, et al.) • • H4 How Do...triumphed over the capitulationist line of Chen Tu-hsiu and Chang Kuo -tao. The Red Army smashed Chiang Kai-shek’s several million enemy troops who...Tung Li- kuo [5516 4539 0948] of the reporting group of the Wuchiao County CCP Committee; Fu Tieh-kuei [0265 6993 2710] of the reporting section of

Development of Nanostructure Materials and Architecture for High Performance Li-rechargeable Batteries with Ultrafast Charge Rate

DTIC Science & Technology

2011-04-22

overcome these difficulties extensive work has been done. Surface coatings with ZnO , SiO2, and Bi2O3 have been proposed to enhance stability of electrodes...Liu, G. Q.; Wen, L.; Liu, Y. M. Journal of Solid State Electrochemistry 2010, 14, 2191. (23) Myung, S. T.; Komaba, S.; Kumagai, N.; Yashiro, H.; Chung...Y. R.; Shu, J.; Zhu, R. S. Journal of Solid State Electrochemistry 2009, 13, 913. (29) Aklalouch, M.; Amarilla, J. M.; Rojas, R. M.; Saadoune, I

What subject matter questions motivate the use of machine learning approaches compared to statistical models for probability prediction?

PubMed

Binder, Harald

2014-07-01

This is a discussion of the following papers: "Probability estimation with machine learning methods for dichotomous and multicategory outcome: Theory" by Jochen Kruppa, Yufeng Liu, Gérard Biau, Michael Kohler, Inke R. König, James D. Malley, and Andreas Ziegler; and "Probability estimation with machine learning methods for dichotomous and multicategory outcome: Applications" by Jochen Kruppa, Yufeng Liu, Hans-Christian Diener, Theresa Holste, Christian Weimar, Inke R. König, and Andreas Ziegler. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Dependency distances in natural mixed languages. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Wang, Lin

2017-07-01

Haitao Liu et al.'s article [1] offers a comprehensive account of the diversity of syntactic patterns in human languages in terms of an important index of memory burden and syntactic difficulty - the dependency distance. Natural languages, a complex system, present overall shorter dependency distances under the universal pressure for dependency distance minimization; however, there exist some relatively-long-distance dependencies, which reflect that language can constantly adapt itself to some deep-level biological or functional constraints.

Proteomic Analysis to Identify Functional Molecules in Drug Resistance Caused by E-Cadherin Knockdown in 3D-Cultured Colorectal Cancer Models

DTIC Science & Technology

2013-09-01

REFERENCES (1) Harsha, H. C.; Pandey, A. Phosphoproteomics in cancer. Mol. Oncol. 2010, 4 (6), 482−95. (2) Iliuk , A.; Liu, X. S.; Xue, L.; Liu, X...based proteomics and peptidomics for biomarker discovery in neurodegenerative diseases. Int. J. Clin. Exp. Pathol. 2009, 2 (2), 132−48. (4) Iliuk , A...phosphoproteins by immobilized metal (Fe3+) affinity chromatography. Anal. Biochem. 1986, 154 (1), 250−4. (6) Iliuk , A. B.; Martin, V. A.; Alicie, B. M

Many particle approximation of the Aw-Rascle-Zhang second order model for vehicular traffic.

PubMed

Francesco, Marco Di; Fagioli, Simone; Rosini, Massimiliano D

2017-02-01

We consider the follow-the-leader approximation of the Aw-Rascle-Zhang (ARZ) model for traffic flow in a multi population formulation. We prove rigorous convergence to weak solutions of the ARZ system in the many particle limit in presence of vacuum. The result is based on uniform BV estimates on the discrete particle velocity. We complement our result with numerical simulations of the particle method compared with some exact solutions to the Riemann problem of the ARZ system.

Combat Veterans with PTSD after Mild TBI Exhibit Greater ERPs from Posterior-medial Cortical Areas While Appraising Facial Features

DTIC Science & Technology

2014-01-01

K.Y., Kim, D.W., Im, C.H., Lee, S.H., 2011. Source imaging of P300 auditory evoked potentials and clinical correlations in patients with posttraumatic...Neural correlates of memories of childhood sexual abuse in womenwith and without posttraumatic stress disorder. Am. J. Psychiatry 156, 1787–1795...S., Zhang, Q., 2011. Neural mechanisms of subliminal priming for traumatic episodic memory: an ERP study. Neurosci. Lett. 498, 10–14. Zhang, K

Quasi-Equilibrium Pairs in Pursuit Games on a Cyclic Graph: Some Modified Cases

DTIC Science & Technology

1989-05-01

CCS Research Report No. 627 QUASI-EQUILIBRIUM PAIRS IN PURSUIT GAMES ON A CYCLIC GRAPH: SOME MODIFIED CASES by A. Charnes D. Zhang i-0 00 CENTER FOR...CCS Research Report No. 627 QUASI-EQUILIBRIUM PAIRS IN PURSUIT GAMES ON A CYCLIC GRAPH: SOME MODIFIED CASES by A. Charnes D. Zhang May 1989 This...University of Texas at Austin Austin, Texas 78712-1177 II (512) 471-1821 APAWNJIZf ] ’ Api, k..s UsW , QUASI-EQUILIBRIUM PAIRS IN PURSUIT GAMES ON A

Improving the multiparty quantum secret sharing over two collective-noise channels against insider attack

NASA Astrophysics Data System (ADS)

Sun, Ying; Wen, Qiao-yan; Zhu, Fu-chen

2010-01-01

The security of the multiparty quantum secret sharing protocol presented by Zhang [Z.J. Zhang, Physica A, 361 (2006) 233] is analyzed. It is shown that this protocol is vulnerable to the insider attack since eavesdropping detection is performed only when all states arrive at the last agent. We propose an attack strategy and give an improved version of the original protocol. The improved protocol is robust and has the same traits with the original one.

Uncooled Cantilever Microbolometer Focal Plane Arrays with mK Temperature Resolution: Engineering Mechanics for the Next Generation

DTIC Science & Technology

2009-11-25

34Nanoindentation Stress-Strain Curves of Plasma Enhanced Chemical Vapor Deposited Silicon Oxide Thin Films," Thin Solid Films, 516 (8) (2008) 1941-1951. 9. S...1604. 5. Z. Cao* and X. Zhang, "Measurement of Stress-Strain Curves of PECVD Silicon Oxide Thin Films by Means of Nanoindentation," in Processing...Microsystems (Transducers 󈧋), Lyon, France, June 10-14, 2007. 9. Z. Cao* and X. Zhang, “Measurement of Stress-strain Curves of PECVD Silicon Oxide

Massachusetts Institute of Technology Consortium Agreement. Phase II

DTIC Science & Technology

1999-03-01

Portable VOR Testing Apparatusthe visual target. Head movements are monitored with magneto-hydrodynamic rotational velocity sensors , and eye motions are...Zhang 4. Miniaturization of the Ring Sensor B-H Yang, H. Asada, K-W. Chang , S. Rhee, Y. Zhang 5. SIMSUIT and Biochair Projects L. Jones, J. Tangorra...No change along 0 a•0a = (2) Neglect Vr = Vr = 0 (Wall velocity of r direction is very small compared with v.’.) a ax ax= (3) As r << x, Dr• >> axx

Mirror Technology Development for the International X-ray Observatory Mission

DTIC Science & Technology

2010-06-06

Solar Panels E xt en si bl e O pt ic al B en ch Focal plane assembly Mirror Assembly ESA JAXA NASA Will Zhang Mirror Tech Days...0.1 m2 0.5 arcsecs 0.4 m2 15 arcsecs 0.2 m2 120 arcsecs St at e of th e A rt IXO Requirement 3 m2 5 arcsecs Will Zhang Mirror...QED Technologies, Rochester, NY Rodriguez Precision Optics, Gonzales, LA Dallas Optical Systems, Inc., Rockwall, TX RAPT Industries, Inc., Freemont

Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zheng, Jinbin, E-mail: jbzheng518@163.com

2014-10-06

In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software.

Resolution-dependent behavior of subgrid-scale vertical transport in the Zhang-McFarlane convection parameterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiao, Heng; Gustafson, Jr., William I.; Hagos, Samson M.

2015-04-18

With this study, to better understand the behavior of quasi-equilibrium-based convection parameterizations at higher resolution, we use a diagnostic framework to examine the resolution-dependence of subgrid-scale vertical transport of moist static energy as parameterized by the Zhang-McFarlane convection parameterization (ZM). Grid-scale input to ZM is supplied by coarsening output from cloud-resolving model (CRM) simulations onto subdomains ranging in size from 8 × 8 to 256 × 256 km 2s.

Development of Conventional and Real-Time Reverse Transcription Polymerase Chain Reaction Assays to Detect Tembusu Virus in Culex tarsalis Mosquitoes

DTIC Science & Technology

2014-08-11

methods for determining potential human health hazards , especially in field environment set- tings. We described the development of sensitive and specific...Smith, Department of Microbiology , Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort...2012. Adapted Tembusu-like virus in chickens and geese in China. J Clin Microbiol 50: 2807–2809. 7. Yun T, Ye W, Ni Z, Zhang D, Zhang C, 2012

New Editors Appointed for Sections of Journal of Geophysical Research

NASA Astrophysics Data System (ADS)

2009-04-01

New editors have been appointed for the Atmospheres, Biogeosciences, and Oceans sections of the Journal of Geophysical Research (JGR). Joost de Gouw (NOAA, Boulder, Colo.) and Renyi Zhang (Texas A&M, College Station) are filling the vacancies of retiring Atmospheres section editors John Austin and Jose Fuentes. De Gouw and Zhang join the continuing editors Steven Ghan and Yinon Rudich. Sara Pryor (Indiana University, Bloomington) is joining the Atmospheres section editorial board as an associate editor now; she will transition to editor in January 2010.

Optimum profit model considering production, quality and sale problem

NASA Astrophysics Data System (ADS)

Chen, Chung-Ho; Lu, Chih-Lun

2011-12-01

Chen and Liu ['Procurement Strategies in the Presence of the Spot Market-an Analytical Framework', Production Planning and Control, 18, 297-309] presented the optimum profit model between the producers and the purchasers for the supply chain system with a pure procurement policy. However, their model with a simple manufacturing cost did not consider the used cost of the customer. In this study, the modified Chen and Liu's model will be addressed for determining the optimum product and process parameters. The authors propose a modified Chen and Liu's model under the two-stage screening procedure. The surrogate variable having a high correlation with the measurable quality characteristic will be directly measured in the first stage. The measurable quality characteristic will be directly measured in the second stage when the product decision cannot be determined in the first stage. The used cost of the customer will be measured by adopting Taguchi's quadratic quality loss function. The optimum purchaser's order quantity, the producer's product price and the process quality level will be jointly determined by maximising the expected profit between them.

Multi-Party Quantum Private Comparison Protocol Based on Entanglement Swapping of Bell Entangled States

NASA Astrophysics Data System (ADS)

Ye, Tian-Yu

2016-09-01

Recently, Liu et al. proposed a two-party quantum private comparison (QPC) protocol using entanglement swapping of Bell entangled state (Commun. Theor. Phys. 57 (2012) 583). Subsequently Liu et al. pointed out that in Liu et al.'s protocol, the TP can extract the two users' secret inputs without being detected by launching the Bell-basis measurement attack, and suggested the corresponding improvement to mend this loophole (Commun. Theor. Phys. 62 (2014) 210). In this paper, we first point out the information leakage problem toward TP existing in both of the above two protocols, and then suggest the corresponding improvement by using the one-way hash function to encrypt the two users' secret inputs. We further put forward the three-party QPC protocol also based on entanglement swapping of Bell entangled state, and then validate its output correctness and its security in detail. Finally, we generalize the three-party QPC protocol into the multi-party case, which can accomplish arbitrary pair's comparison of equality among K users within one execution. Supported by the National Natural Science Foundation of China under Grant No. 61402407

An improved authenticated key agreement protocol for telecare medicine information system.

PubMed

Liu, Wenhao; Xie, Qi; Wang, Shengbao; Hu, Bin

2016-01-01

In telecare medicine information systems (TMIS), identity authentication of patients plays an important role and has been widely studied in the research field. Generally, it is realized by an authenticated key agreement protocol, and many such protocols were proposed in the literature. Recently, Zhang et al. pointed out that Islam et al.'s protocol suffers from the following security weaknesses: (1) Any legal but malicious patient can reveal other user's identity; (2) An attacker can launch off-line password guessing attack and the impersonation attack if the patient's identity is compromised. Zhang et al. also proposed an improved authenticated key agreement scheme with privacy protection for TMIS. However, in this paper, we point out that Zhang et al.'s scheme cannot resist off-line password guessing attack, and it fails to provide the revocation of lost/stolen smartcard. In order to overcome these weaknesses, we propose an improved protocol, the security and authentication of which can be proven using applied pi calculus based formal verification tool ProVerif.

Committees

NASA Astrophysics Data System (ADS)

2012-11-01

Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro Quebec IREQ, Varennes Canada Etienne PARKINSON Andritz Hydro Ltd. Switzerland B V S S S PRASAD Indian Institute of Technology Madras India Stefan RIEDELBAUCH Stuttgart University Germany Michel SABOURIN Alstom Hydro Canada Inc Canada Bruno SCHIAVELLO Flowserve Corporation USA Katsumasa SHIMMEI Hitachi Ltd Japan Christoph SINGRTüN VDMA Germany Ale? SKOTAK CKD Blansko Engineering, a s Czech Republic Toshiaki SUZUKI Toshiba Corporation Japan Andy C C TAN Queensland University of Technology Australia Geraldo TIAGO FILHO Universidade Federal de Itajuba Brazi Thi C VU Andritz Hydro Ltd Canada Satoshi WATANABE Kyushu University Japan S H WINOTO National University of Singapore Singapore Woo-Seong WOO STX Institute of Technology Korea International Technical Committee François AVELLAN (principal) EPFL-LMH Switzerland Xingqi LUO (principal) Xi'an University of Technology China Martin BÖHLE Kaiserslautern University Germany Gerard BOIS ENSAM France Young-Seok CHOI KITECH Korea Luca d'AGOSTINO University of Pisa Italy Eduard EGUSQUIZA Polytechnical University Catalonia Spain Arpad FAY University of Miskolcz Hungary Richard FISHER Voith Hydro Inc USA Regiane FORTES-PATELLA Institute Polytechnique de Grenoble France Aleksandar GAJIC University of Belgrade Serbia José GONZÁLEZ Universidad de Oviedo Spain François GUIBAULT Ecole Polytechnique de Montreal Canada Toshiaki IKOHAGI Tohoku University Japan Chisachi KATO University of Tokyo Japan Kwang-Yong KIM Inha University Korea Youn-Jea KIM Sungkyunkwan University Korea Smaine KOUIDRI Université Pierre et Marie Curie (Paris 6) France Shengcai LI Warwick University UK Adrian LUNGU Dunarea de Jos University of Galati Romania Torbjøm K NIELSEN NTNU Norway Michihiro NISHI Tsinghua University China Peter PELZ Darmstadt University Germany Frantisek POCHYLY Brno University Czech Republic Albert RUPRECHT University of Stuttgart Germany Rudolf SCHILLING Technische University München Germany Wei SHYY HKUST Hong Kong,China Romeo SUSAN-RESIGA Politehnica University of Timisoara Romania Kazuhiro TANAKA Kyushu Institute of Technology Japan Yoshinobu TSUJIMOTO Osaka University Japan Local Organizing Committee Chairman Yulin WU Tsinghua University Beijing Executive Chairman Zhengwei WANG Tsinghua University Beijing Members Shuliang CAO Tsinghua University Beijing Cichang CHEN South West University of Petroleum Chengdu Hongxun CHEN Shanghai University Shanghai Jiang DAI China Sanxia General Co Yichang Huashu DOU National University of Singapore Singapore Fengqin HAN Huanan University of Sci & Tech Guangzhou Kun LI Hefei Inst of General Machinery Hefei Rennian LI Lanzhou University of Sci & Tech Lanzhou Wanhong LI National Natural Science Foundation of China Beijing Chao LIU Yangzhou University Yangzhou Li LU China Inst of Water Resources and Hydropower Research Beijing Xingqi LUO Xi'an University of Tech Xi'an Zhenyue MA Dalian University of Sci & Tech Dalian Jiegang MU Zhejiang University of Tech Hangzhou Daqing QIN Harbin Electric Machinery Group Harbin Fujun WANG China Agriculture University Beijing Guoyu WANG Beijing Institute of Technology (BIT) Beijing Leqin WANG Zhejiang University Hangzhou Yuzhen WU NERCSPV Beijing Hongyuan XU Tsinghua University Beijing Jiandong YANG Wuhan University Wuhan Minguan YANG Jiangsu University Zhenjiang Shouqi YUAN Jiangsu University Zhenjiang Lefu ZHANG Harbin Electric Machinery Group Harbin Lixiang ZHANG Yunnan University of Sci & Tech Kunming Shengchang ZHANG Zhejiang University of Tech Hangzhou Kun ZHAO China Water & Electric Consulting Corp Beijing Yuan ZHENG Hehai University Nanjing Jianzhong ZHOU Huazhong University of Sci & Tech Wuhan Lingjiu ZHOU China Agriculture University Beijing Hongwu ZHU China Petroleum University Beijing Zuchao ZHU Zhejiang Sci-Tech University Hangzhou Secretaries Shuhong LIU (Academic), liushuhong@tsinghua.edu.cn Xianwu LUO (Registration), luoxw@tsinghua.edu.cn Baoshan ZHU (Finance), bszhu@mail.tsinghua.edu.cn

Electronic structure of antifluorite Cu{sub 2}X (X = S, Se, Te) within the modified Becke-Johnson potential plus an on-site Coulomb U

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Yubo; Wang, Youwei; Xi, Lili

The traditional photon absorbers Cu{sub 2−x}X (X = S, Se, and Te) have regained significant research attention in the search of earth-abundant photovoltaic materials. These moderate- and narrow-gap materials have also been shown to exhibit excellent thermoelectric properties recently. However, semimetallic band structures with inverted band orderings are predicted for antifluorite structure Cu{sub 2}X using density functional theory with the local density approximation or the generalized gradient approximation. We find that semiconducting band structures and normal band orderings can be obtained using the modified Becke-Johnson potential plus an on-site Coulomb U (the mBJ+U approach), which is consistent with our earliermore » finding for diamond-like Cu-based multinary semiconductors [Y. Zhang, J. Zhang, W. Gao, T. A. Abtew, Y. Wang, P. Zhang, and W. Zhang, J. Chem. Phys. 139, 184706 (2013)]. The trend of the chemical bonding of Cu{sub 2}X is analyzed, which shows that the positions of the valence band maximum and conduction band minimum are strongly affected by the inter-site pd and intra-site sp hybridizations, respectively. The calculated gaps of Cu{sub 2}S and Cu{sub 2}Se still seem to be underestimated compared with experimental results. We also discuss the effects of different structural phases and Cu disordering and deficiency on the bandgaps of these materials.« less

Projectivity is the mathematical code of syntax. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Ninio, Anat

2017-07-01

The thought-provoking proposal by Liu, Xu and Liang [1] to integrate cognitive considerations involved in Dependency distance minimization (DDM) in syntactic theory will, I am sure, be much discussed in the literature. The authors are to be congratulated for a most serious, thorough and mature presentation. I am sure that DDM will find its rightful place alongside other cognitive factors that are considered to significantly affect the structure and evolution of language such as frequency with its serious impact on grammaticalization [2].

Path integral formulation of the Hodge duality on the brane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hahn, Sang-Ok; Kiem, Youngjai; Kim, Yoonbai

In the warped compactification with a single Randall-Sundrum brane, a puzzling claim has been made that scalar fields can be bound to the brane but their Hodge dual higher-rank antisymmetric tensors cannot. By explicitly requiring the Hodge duality, a prescription to resolve this puzzle was recently proposed by Duff and Liu. In this Brief Report, we implement the Hodge duality via the path integral formulation in the presence of the background gravity fields of warped compactifications. It is shown that the prescription of Duff and Liu can be naturally understood within this framework.

Improving the Prediction of Mortality and the Need for Life-Saving Interventions in Trauma Patients Using Standard Vital Signs With Heart-Rate Variability and Complexity

DTIC Science & Technology

2015-06-01

Trauma 69:S10YS13, 2010. 2. Liu NT, Holcomb JB, Wade CE, Darrah MI, Salinas J: Utility of vital signs, heart-rate variability and complexity, and machine ... learning for identifying the need for life-saving interventions in trauma patients. Shock 42:108Y114, 2014. 3. Pickering TG, Shimbo D, Hass D...Ann Emerg Med 45:68Y76, 2005. 8. Liu NT, Holcomb JB, Wade CE, Batchinsky AI, Cancio LC, Darrah MI, Salinas J: Development and validation of a machine

The Impact of the Internet on Health Consultation Market Concentration: An Econometric Analysis of Secondary Data.

PubMed

Li, Jia; Zhang, Ya; Ma, Ling; Liu, Xuan

2016-10-28

Many markets have traditionally been dominated by a few best-selling products, and this is also the case for the health care industry. However, we do not know whether the market will be more or less concentrated when health care services are delivered online (known as E-consultation), nor do we know how to reduce the concentration of the E-consultation market. The aim of this study was to investigate the concentration of the E-consultation market and how to reduce its concentration through information disclosure mechanisms (online reputation and self-representation). We employed a secondary data econometric analysis using transaction data obtained from an E-consultation Website (haodf.com) for three diseases (infantile pneumonia, diabetes, and pancreatic cancer) from 2008 to 2015. We included 2439 doctors in the analysis. The E-consultation market largely follows the 20/80 principle, namely that approximately 80% of orders are fulfilled by nearly 20% of doctors. This is much higher than the offline health care market. Meanwhile, the market served by doctors with strong online reputations (beta=0.207, P<.001) or strong online self-representation (beta=0.386, P<.001) is less concentrated. When health care services are delivered online, the market will be more concentrated (known as the "Superstar" effect), indicating poor service efficiency for society as a whole. To reduce market concentration, E-consultation websites should provide important design elements such as ratings of doctors (user feedback), articles contributed by doctors, and free consultation services (online representation). A possible and important way to reduce the market concentration of the E-consultation market is to accumulate enough highly rated or highly self-represented doctors. ©Jia Li, Ya Zhang, Ling Ma, Xuan Liu. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 28.10.2016.

Self-evaluated and Close Relative-Evaluated Epworth Sleepiness Scale vs. Multiple Sleep Latency Test in Patients with Obstructive Sleep Apnea

PubMed Central

Li, Yun; Zhang, Jihui; Lei, Fei; Liu, Hong; Li, Zhe; Tang, Xiangdong

2014-01-01

Objectives: The aims of this study were to determine (1) the agreement in Epworth Sleepiness Scale (ESS) evaluated by patients and their close relatives (CRs), and (2) the correlation of objective sleepiness as measured by multiple sleep latency test (MSLT) with self-evaluated and close relative-evaluated ESS. Methods: A total of 85 consecutive patients with obstructive sleep apnea (OSA) (70 males, age 46.7 ± 12.9 years old) with an apnea-hypopnea index (AHI) > 5 events per hour (mean 38.9 ± 26.8/h) were recruited into this study. All participants underwent an overnight polysomnographic assessment (PSG), MSLT, and ESS rated by both patients and their CRs. Mean sleep latency < 8 min on MSLT was considered objective daytime sleepiness. Results: Self-evaluated global ESS score (ESSG) was closely correlated with evaluation by CRs (r = 0.79, p < 0.001); the mean ESSG score evaluated by patients did not significantly differ from that evaluated by CRs (p > 0.05). However, Bland- Altman plot showed individual differences between self-evaluated and CR-evaluated ESS scores, with a 95%CI of -9.3 to 7.0. The mean sleep latency on MSLT was significantly associated with CR-evaluated ESSG (r = -0.23, p < 0.05); significance of association with self-evaluated ESSG was marginal (r = -0.21, p = 0.05). Conclusions: CR-evaluated ESS has a good correlation but also significant individual disagreement with self-evaluated ESS in Chinese patients with OSA. CR-evaluated ESS performs as well as, if not better than, self-evaluated ESS in this population when referring to MSLT. Citation: Li Y; Zhang J; Lei F; Liu H; Li Z; Tang X. Self-evaluated and close relative-evaluated Epworth Sleepiness Scale vs. multiple sleep latency test in patients with obstructive sleep apnea. J Clin Sleep Med 2014;10(2):171-176. PMID:24533000

O-H bond dissociation enthalpies in oximes: order restored.

PubMed

Pratt, Derek A; Blake, Jessie A; Mulder, Peter; Walton, John C; Korth, Hans-Gert; Ingold, Keith U

2004-09-01

The O-H bond dissociation enthalpies (BDEs) of 13 oximes, RR'C=NOH, having R and/or R' = H, alkyl, and aryl are reported. Experimental anchor points used to validate the results of theoretical calculations include (1) the O-H BDEs of (t-Bu)2C=NOH, t-Bu(i-Pr)C=NOH, and t-Bu(1-Ad)C=NOH determined earlier from the heat released in the reaction of (t-Bu)2C=NO* with (PhNH)2 in benzene and EPR spectroscopy (Mahoney, L. R.; Mendenhall, G. D.; Ingold, K. U. J. Am. Chem. Soc. 1973, 95, 8610), all of which were decreased by 1.7 kcal/mol to reflect a revision to the heat of formation of (E)-azobenzene (which has significant ramifications for other BDEs) and to correct for the heat of hydrogen bonding of (t-Bu)2C=NOH (alphaH2 = 0.43 measured in this work) to benzene, and (2) the measured rates of thermal decomposition of six RR'C=NOCH2Ph at 423 or 443 K, which were used to derive O-H BDEs for the corresponding RR'C=NOH. Claims (Bordwell, F. G.; Ji, G. Z. J. Org. Chem. 1992, 57, 3019; Bordwell, F. G.; Zhang, S. J. Am. Chem. Soc. 1995, 117, 4858; and Bordwell, F. G.; Liu, W.-Z. J. Am. Chem. Soc. 1996, 118, 10819) that the O-H BDEs in mono- and diaryloximes are significantly lower than those for alkyloximes due to delocalization of the unpaired electron into the aromatic ring have always been inconsistent with the known structures of iminoxyl radicals as are the purported perpendicular structures, i.e., phi(Calpha-C=N-O*) = 90 degrees, for sterically hindered dialkyl iminoxyl radicals. The present results confirm the 1973 conclusion that simple steric effects, not electron delocalization or dramatic geometric changes, are responsible for the rather small differences in oxime O-H BDEs. Copyright 2004 American Chemical Society

Constraints on cosmological models and reconstructing the acceleration history of the Universe with gamma-ray burst distance indicators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liang Nan; Wu Puxun; Zhang Shuangnan

2010-04-15

Gamma-ray bursts (GRBs) have been regarded as standard candles at very high redshift for cosmology research. We have proposed a new method to calibrate GRB distance indicators with Type Ia supernova (SNe Ia) data in a completely cosmology-independent way to avoid the circularity problem that had limited the direct use of GRBs to probe cosmology [N. Liang, W. K. Xiao, Y. Liu, and S. N. Zhang, Astrophys. J. 685, 354 (2008).]. In this paper, a simple method is provided to combine GRB data into the joint observational data analysis to constrain cosmological models; in this method those SNe Ia datamore » points used for calibrating the GRB data are not used to avoid any correlation between them. We find that the {Lambda}CDM model is consistent with the joint data in the 1-{sigma} confidence region, using the GRB data at high redshift calibrated with the interpolating method, the Constitution set of SNe Ia, the cosmic microwave background radiation from Wilkinson Microwave Anisotropy Probe five year observation, the baryonic acoustic oscillation from the spectroscopic Sloan Digital Sky Survey Data Release 7 galaxy sample, the x-ray baryon mass fraction in clusters of galaxies, and the observational Hubble parameter versus redshift data. Comparing to the joint constraints with GRBs and without GRBs, we find that the contribution of GRBs to the joint cosmological constraints is a slight shift in the confidence regions of cosmological parameters to better enclose the {Lambda}CDM model. Finally, we reconstruct the acceleration history of the Universe up to z>6 with the distance moduli of SNe Ia and GRBs and find some features that deviate from the {Lambda}CDM model and seem to favor oscillatory cosmology models; however, further investigations are needed to better understand the situation.« less

REV-ERBs agonism suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss partially via FABP4 upregulation.

PubMed

Song, Chao; Tan, Peng; Zhang, Zheng; Wu, Wei; Dong, Yonghui; Zhao, Liming; Liu, Huiyong; Guan, Hanfeng; Li, Feng

2018-01-22

REV-ERBs (REV-ERBα and REV-ERBβ) are transcription repressors and circadian regulators. Previous investigations have shown that REV-ERBs repress the expression of target genes, including MMP9 and CX3CR1, in macrophages. Because MMP9 and CX3CR1 reportedly participate in receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis, we inferred that REV-ERBs might play a role in osteoclastogenesis. In the present study, we found that the REV-ERBα level decreased significantly during RANKL-induced osteoclast differentiation from primary bone marrow-derived macrophages (BMMs). REV-ERBα knockdown by small interfering RNA in BMMs resulted in the enhanced formation of osteoclasts, whereas REV-ERBβ knockdown showed no effect on osteoclast differentiation. Moreover, the REV-ERB agonist SR9009 inhibited osteoclast differentiation and bone resorption. Intraperitoneal SR9009 administration prevented ovariectomy-induced bone loss; this effect was accompanied by decreased serum RANKL and C-terminal telopeptide of type I collagen levels and increased osteoprotegerin levels. Further investigation revealed that NF-κB and MAPK activation and nuclear factor of activated T cells, cytoplasmic 1, and c-fos expression were suppressed by SR9009. The level of reactive oxygen species was also decreased by SR9009, with NADPH oxidase subunits also being down-regulated. In addition, an expression microarray showed that FABP4, an intracellular lipid-binding protein, was up-regulated by REV-ERB agonism. BMS309403, an inhibitor of FABP4, partially prevented the suppression of osteoclastogenesis by SR9009 through stabilizing phosphorylation of p65. To summarize, our results proved that the REV-ERB agonism inhibited osteoclastogenesis partially via FABP4 up-regulation.-Song, C., Tan, P., Zhang, Z., Wu, W., Dong, Y., Zhao, L., Liu, H., Guan, H., Li, F. REV-ERBs agonism suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss partially via FABP4 upregulation.

Reconciling late Quaternary transgressions in the Bohai Sea, China to the global sea level changes, and new linkage of sedimentary records to three astronomical rhythms

NASA Astrophysics Data System (ADS)

Yi, Liang

2013-04-01

The Bohai Sea in China was formed by subsidence during the Cenozoic. Some 2000-3000 m of fluvial, lacustrine and marine sediments has been deposited in the basin (IOCAS 1985), and these sediments have great potentials in high-/low-latitude interaction, environmental impacts on ancient human activities, and other important issues (Liu, 2009; Yi et al. 2012a), because it is influenced by the Siberian-Mongolian Highs and the ITCZ, and is close to the Nihewan basin and the Zhoukoudian site which are both world-renowned for the discovery of Homo erectus. Since the 1970s, hundreds of studies have been conducted around the Bohai Sea and the major results could be summarized as follows (Zhao et al., 1978; IOCAS, 1985; Liu, 2009, and references therein): (1) constrained by radiocarbon dating, TL/OSL or geomagnetic excursion, three transgressions (T1, T2, T3) developed during the Holocene, marine isotopic stage (MIS) 3 and MIS 5, respectively; and (2) regressions occurred at the beginning of glacial stages, i.e. MIS2 and MIS4. However, apparent inconsistency could be found between T2 and T3, and the question is that in the context that MIS 3 is an inter-stadial stage with a global sea level of 60~80 m lower than the present (Chappell et al. 1996), how did T2 occur in the Bohai Sea, and why did T2 have much larger influence than T3 which occurred at the beginning of MIS 5? To correlate regional environmental changes with global pattern and thus to detect the potential interaction between various driving factors on orbital timescales, three cores with a high recovery rate were drilled in the south Bohai Sea. This study was conducted following three perspectives: chronology (Yi et al. 2012b), sea-level change (Yi et al. 2012c) and paleoclimatology (Yi et al. 2012a), and the main results are as follows: 1. Chronology. Luminescence and radiocarbon dating methods were applied in dating these coastal/marine sediments: (1) For Holocene samples, most of the radiocarbon dates agree well with OSL ages. (2) For pre-Holocene samples, radiocarbon dates cluster at 40-50 14C ka BP, whereas OSL ages are in stratigraphic order from 11 to 176 ka. Because the self-consistency of the quartz OSL ages and the stratigraphic agreement in the three cores, we suggested that the quartz OSL ages are more reliable with respect to date the samples from the south Bohai Sea. (3) The three marine stratums identified in the south Bohai Sea are likely to be formed during the Holocene, MIS 3-5, and MIS 6-7, respectively. 2. Sea-level change. Because of uncertainties in regionally tectonic activities and insufficient fossils deposited in the sediment, the methods develop for sea-level studies, i.e. the exploitation of dated geomorphologic features and the biologically based sea-level transfer functions, can not be applied in this area. Thus, we first develop a proxy from sediment grain-size analysis with clear indicative meaning, and then quantitatively reconstruct sea-level variation for the south Bohai Sea. The reconstruction indicates that relative sea-level changes in the study area track global sea-level variation, and also indicate substantial regression from 70 to 30 ka, and potentially subarial exposure from 38 to 20 ka. Our results document the feasibility of reconstructing relative sea-level change by numerical partitioning of sediment grain size data, demonstrating the potential for future applications. 3. Paleoclimatology. Three proxy indices were employed, i.e. grain size, magnetic susceptibility and tree-pollen abundance, to infer paleoenviromental changes. When placed on the calibrated radiocarbon and OSL based age model, bulk sediment variations in grain size demonstrated potential modulation in response to the Asian monsoon intensity (Wang et al., 2001, 2008; Cheng et al., 2009), and thus we refined the chronology through astronomically tuning it to the July insolation at 65°N synchronously, in accordance with the method of Ding et al. (1994). The most noticeable feature of these coastal sediment variations is the little internal similarity between records compared with high similarity with external forcing indicating that the coastal sediments in the south Bohai Sea integrate different influences from various environmental factors: (1) the grain-size variation represents Asian monsoon intensity which was dominated by both solar insolation (major) and global ice volume (minor) forcing; (2) the magnetic susceptibility indicates river incision processes which were sensitive to orbital tilt with influence from solar insolation; (3) the vegetation coverage responded to global ice volume coupled obliquity changes; and that (4) neither external nor internal factors could dominate the paleoenvironmental evolution on orbital timescales in an independent way, and they are both integrated in a complex pattern. Therefore, combining all of these results, we report those great similarities between regional and global sea-level patterns and the nonlinear interaction and the complex response to driving processes in a coastal evolution. However, all of these studies only used the upper part of cores within marine strata, and the rest containing lacustrine sediment is still in process. Sediment grain size, magnetic susceptibility, color reflectance were finished, and the magnetostratigraphic, environmental magnetism and element analysis are ongoing. More results about high-/low-latitude interaction and relative sea level will be released in three years, and anyone who has interests in cooperation will be welcome (Email: yi.liang82@gmail.com). References Chappell, J., Omura, A., Esat, T., McCulloch, M., Pandolfi, J., Ota, Y., Pillans, B., 1996. Reconciliation of late Quaternary sea levels derived from coral terraces at Huon Peninsula with deep sea oxygen isotope records. Earth and Planetary Science Letters 141, 227-236. Cheng, H., Edwards, R.L., Broecker, W.S., Denton, G.H., Kong, X., Wang, Y., Zhang, R., Wang, X., 2009. Ice Age Terminations. Science 326, 248-252. Ding, Z.L., Yu, Z.W., Rutter, N.W., Liu, T.S., 1994. Towards an orbital time scale for chinese loess deposits. Quaternary Science Reviews 13, 39-70. IOCAS (Institute of Oceanology, Chinese Academy of Sciences), 1985. Bohai Sea Geology. Science Press, Beijing, China. Liu, T., 2009. Loess and Arid Environment. Anhui Science & Techonology Press, Hefei, China. Wang, Y., Cheng, H., Edwards, R.L., An, Z., Wu, J., Chen, C.-C., Dorale, J.A., 2001. A High-Resolution Absolute-Dated Late Pleistocene Monsoon Record from Hulu Cave, China. Science 294, 2345-2348. Wang, Y., Cheng, H., Edwards, R.L., Kong, X., Shao, X., Chen, S., Wu, J., Jiang, X., Wang, X., An, Z., 2008. Millennial- and orbital-scale changes in the East Asian monsoon over the past 224,000 years. Nature 451, 1090-1093. Yi, L., Yu, H., Ortiz, J.D., Xu, X., Chen, S., Ge, J., Hao, Q., Yao, J., Shi, X., Peng, S., 2012a. Late Quaternary linkage of sedimentary records to three astronomical rhythms and the Asian monsoon, inferred from a coastal borehole in the south Bohai Sea, China. Palaeogeography, Palaeoclimatology, Palaeoecology 329-310, 101-117. Yi, L., Lai, Z.P., Yu, H.J., Xu, X.Y., Su, Q., Yao, J., Wang, X.L., Shi, X., 2012b. Chronologies of sedimentary changes in the south Bohai Sea, China: Constraints from luminescence and radiocarbon dating. Boreas, doi: 10.1111/j.1502-3885.2012.00271.x. Yi, L., Yu, H.J., Ortiz, J.D., Xu, X.Y., Qiang, X.K., Huang, H.J., Shi, X., Deng, C.L., 2012c. A reconstruction of late Pleistocene relative sea level in the south Bohai Sea, China, based on sediment grain-size analysis. Sedimentary Geology 281, 88-100. Zhao, S., Yang, G., Cang, S., Zhang, H., Huang, Q., Xia, D., Wang, Y., Liu, F., Liu, C., 1978. Transgression's stratas and shoreline changes in the south coast of Bohai Bay, China. Oceanologia et Limnologia Sinica 9, 15-25.

Reply to comment by Ma and Zhang on "Rescaling the complementary relationship for land surface evaporation"

NASA Astrophysics Data System (ADS)

Crago, Richard; Qualls, Russell; Szilagyi, Jozsef; Huntington, Justin

2017-07-01

Ma and Zhang (2017) note a concern they have with our rescaled Complementary Relationship (CR) for land surface evaporation when daily average wind speeds are very low (perhaps less than 1 m/s). We discuss conditions and specific formulations that lead to this concern, but ultimately argue that under these conditions, a key assumption behind the CR itself may not be satisfied at the daily time scale. Thus, careful consideration of the reliability of the CR is needed when wind speeds are very low.

Progress in Understanding the Impacts of 3-D Cloud Structure on MODIS Cloud Property Retrievals for Marine Boundary Layer Clouds

NASA Technical Reports Server (NTRS)

Zhang, Zhibo; Werner, Frank; Miller, Daniel; Platnick, Steven; Ackerman, Andrew; DiGirolamo, Larry; Meyer, Kerry; Marshak, Alexander; Wind, Galina; Zhao, Guangyu

2016-01-01

Theory: A novel framework based on 2-D Tayler expansion for quantifying the uncertainty in MODIS retrievals caused by sub-pixel reflectance inhomogeneity. (Zhang et al. 2016). How cloud vertical structure influences MODIS LWP retrievals. (Miller et al. 2016). Observation: Analysis of failed MODIS cloud property retrievals. (Cho et al. 2015). Cloud property retrievals from 15m resolution ASTER observations. (Werner et al. 2016). Modeling: LES-Satellite observation simulator (Zhang et al. 2012, Miller et al. 2016).

Rational Combination Immunotherapy: Understand the Biology.

PubMed

Kaufman, Howard L

2017-05-01

Selecting rational treatment combinations remains a major challenge for improving immunotherapy outcomes. In this issue of Cancer Immunology Research , Zhang and colleagues reduced tumors by inhibiting CD47 in a lung carcinoma model, a treatment that inadvertently induced autophagy through inhibition of the Akt/mTOR pathway. By also targeting autophagy, the therapeutic response improved, highlighting the importance of understanding the biology beneath antitumor immunity. Cancer Immunol Res; 5(5); 355-6. ©2017 AACR See article by Zhang et al., p. 363. ©2017 American Association for Cancer Research.

Radiation Resistant Polymer-Based Photonics for Space Applications

DTIC Science & Technology

2006-08-01

M. Flusche", P. Repak", G. Brost’, A. Pirichb, D. CraigC D. Lee’, D. Cardimona’, H. R. Fetterman ’, B. Tsape, C. Castaneda, R. , T. zengh, D. Wood", R...Repak, G. Brost, A. Pirich; D. Le, D. Cardimona, D. Craig; H. Fetterman , B. Tsap; C. Castaneda; R. Barto; T. Zeng, D. Wood, R. Claus, AFRL/SNDP 25...124, 3, 2001. [2] M.-C.Oh, H. Zhang, C. Zhang, H. Erlig, Y. Chang, B. Tsap, D. Chang, A. Szep, W. H. Steier, H. R. Fetterman , and L. R. Dalton,, IEEE

Chinese patent medicine Fei-Liu-Ping ointment as an adjunctive treatment for non-small cell lung cancer: protocol for a systematic review.

PubMed

Zheng, Honggang; He, Shulin; Liu, Rui; Xu, Xinyao; Xu, Tao; Chen, Shuntai; Guo, Qiujun; Gao, Yebo; Hua, Baojin

2017-01-16

Fei-Liu-Ping ointment has been widely applied as adjunctive drug in the treatment of non-small cell lung cancer (NSCLC). However, there has been no systematic review of research findings regarding the efficacy of this treatment. Here, we provide a protocol for assessing the effectiveness and safety of Fei-Liu-Ping ointment in the treatment of NSCLC. The electronic databases to be searched will include MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, Excerpt Medica Database (EMBASE), China National Knowledge Infrastructure (CNKI), China Scientific Journal Database (VIP), Wanfang Database and Chinese Biomedical Literature Database (CBM). Papers in English or Chinese published from inception to 2016 will be included without any restrictions. We will conduct a meta-analysis of randomised controlled trial if possible. The therapeutic effects according to the standard for treatment of solid tumours by the WHO and the quality of life as evaluated by Karnofsky score and weight will be applied as the primary outcomes. We will also evaluate the data synthesis and risk of bias using Review Manager 5.3 software. The results of this review will offer implications for the use of Fei-Liu-Ping ointment as an adjunctive treatment for NSCLC. This knowledge will inform recommendations by surgeons and researchers who are interested in the treatment of NSCLC. The results of this systematic review will be disseminated through presentation at a conference and publication of the data in a peer-reviewed journal. PROSPERO CRD42016036911. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

[Comparison of three daily global solar radiation models].

PubMed

Yang, Jin-Ming; Fan, Wen-Yi; Zhao, Ying-Hui

2014-08-01

Three daily global solar radiation estimation models ( Å-P model, Thornton-Running model and model provided by Liu Ke-qun et al.) were analyzed and compared using data of 13 weather stations from 1982 to 2012 from three northeastern provinces and eastern Inner Mongolia. After cross-validation analysis, the result showed that mean absolute error (MAE) for each model was 1.71, 2.83 and 1.68 MJ x m(-2) x d(-1) respectively, showing that Å-P model and model provided by Liu Ke-qun et al. which used percentage of sunshine had an advantage over Thornton-Running model which didn't use percentage of sunshine. Model provided by Liu Ke-qun et al. played a good effect on the situation of non-sunshine, and its MAE and bias percentage were 18.5% and 33.8% smaller than those of Å-P model, respectively. High precision results could be obtained by using the simple linear model of Å-P. Å-P model, Thornton-Running model and model provided by Liu Ke-qun et al. overvalued daily global solar radiation by 12.2%, 19.2% and 9.9% respectively. MAE for each station varied little with the spatial change of location, and annual MAE decreased with the advance of years. The reason for this might be that the change of observation accuracy caused by the replacement of radiation instrument in 1993. MAEs for rainy days, non-sunshine days and warm seasons of the three models were greater than those for days without rain, sunshine days and cold seasons respectively, showing that different methods should be used for different weather conditions on estimating solar radiation with meteorological elements.

Comparative Genomics of Regulation of Fatty Acid and Branched-chain Amino Acid Utilization in Proteobacteria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kazakov, Alexey E.; Rodionov, Dmitry A.; Arkin, Adam Paul

2008-10-31

Bacteria can use branched-chain amino acids (ILV, i.e. isoleucine, leucine, valine) and fatty acids (FA) as sole carbon and energy sources convering ILV into acetyl-CoA, propanoyl-CoA and propionyl-CoA, respectively. In this work, we used the comparative genomic approach to identify candidate transcriptional factors and DNA motifs that control ILV and FA utilization pathways in proteobacteria. The metabolic regulons were characterized based on the identification and comparison of candidate transcription factor binding sites in groups of phylogenetically related genomes. The reconstructed ILV/FA regulatory network demonstrates considerable variability and involves six transcriptional factors from the MerR, TetR and GntR families binding tomore » eleven distinct DNA motifs. The ILV degradation genes in gamma- and beta-proteobacteria are mainly regulated by anovel regulator from the MerR family (e.g., LiuR in Pseudomonas aeruginosa) (40 species), in addition, the TetR-type regulator LiuQ was identified in some beta-proteobacteria (8 species). Besides the core set of ILV utilization genes, the LiuR regulon in some lineages is expanded to include genes from other metabolic pathways, such as the glyoxylate shunt and glutamate synthase in the Shewanella species. The FA degradation genes are controlled by four regulators including FadR in gamma-proteobacteria (34 species), PsrA in gamma- and beta-proteobacteria (45 species), FadP in beta-proteobacteria (14 species), and LiuR orthologs in alpha-proteobacteria (22 species). The remarkable variability of the regulatory systems associated with the FA degradation pathway is discussed from the functional and evolutionary points of view.« less

Relativistic distorted-wave collision strengths for the 16 Δn=0 optically allowed transitions with n=2 in the 67 O-like ions with 26≤Z≤92

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fontes, Christopher J., E-mail: cjf@lanl.gov; Zhang, Hong Lin

2015-01-15

Relativistic distorted-wave collision strengths have been calculated for the 16 Δn=0 optically allowed transitions with n=2 in the 67 O-like ions with nuclear charge number Z in the range 26≤Z≤92. The calculations were made for the four final, or scattered, electron energies E{sup ′}=0.20,0.42,0.80, and 1.40, where E{sup ′} is in units of Z{sub eff}{sup 2} Ry with Z{sub eff}=Z−5.83. In the present calculations, an improved “top-up” method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb–Bethe approximation used in previous work by Zhang and Sampson [H.L.more » Zhang, D.H. Sampson, At. Data Nucl. Data Tables 82 (2002) 357]. In that earlier work, collision strengths were also provided for O-like ions, but for a more comprehensive data set consisting of all possible 45 Δn=0 transitions, six scattered energies, and the 79 ions with Z in the range 14≤Z≤92. The collision strengths covered in the present work should be more accurate than the corresponding data given by Zhang and Sampson [H.L. Zhang, D.H. Sampson, At. Data Nucl. Data Tables 82 (2002) 357] and are presented here to replace those earlier results.« less

Relativistic distorted-wave collision strengths for the 49 Δn=0 optically allowed transitions with n=2 in the 67 B-like ions with 26≤Z≤92

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fontes, Christopher J., E-mail: cjf@lanl.gov; Zhang, Hong Lin

2014-05-15

Relativistic distorted-wave collision strengths have been calculated for the 49 Δn=0 optically allowed transitions with n=2 in the 67 B-like ions with nuclear charge number Z in the range 26≤Z≤92. The calculations were made for the four final, or scattered, electron energies E{sup ′}=0.20, 0.42, 0.80, and 1.40, where E{sup ′} is in units of Z{sub eff}{sup 2} Ry with Z{sub eff}=Z−3.33. In the present calculations, an improved “top-up” method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb–Bethe approximation used in previous work by Zhang andmore » Sampson [H.L. Zhang and D.H. Sampson, At. Data Nucl. Data Tables 56 (1994) 41]. In that earlier work, collision strengths were also provided for B-like ions, but for a more comprehensive data set consisting of all 105 Δn=0 transitions, six scattered energies and the 85 ions with Z in the range 8≤Z≤92. The collision strengths covered in the present work should be more accurate than the corresponding data given by Zhang and Sampson [H.L. Zhang and D.H. Sampson, At. Data Nucl. Data Tables 56 (1994) 41] and are presented here to replace those earlier results.« less

Eight-dimensional quantum reaction rate calculations for the H+CH{sub 4} and H{sub 2}+CH{sub 3} reactions on recent potential energy surfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Yong; Zhang, Dong H., E-mail: zhangdh@dicp.ac.cn

2014-11-21

Eight-dimensional (8D) transition-state wave packet simulations have been performed on two latest potential energy surfaces (PES), the Zhou-Fu-Wang-Collins-Zhang (ZFWCZ) PES [Y. Zhou, B. Fu, C. Wang, M. A. Collins, and D. H. Zhang, J. Chem. Phys. 134, 064323 (2011)] and the Xu-Chen-Zhang (XCZ)-neural networks (NN) PES [X. Xu, J. Chen, and D. H. Zhang, Chin. J. Chem. Phys. 27, 373 (2014)]. Reaction rate constants for both the H+CH{sub 4} reaction and the H{sub 2}+CH{sub 3} reaction are calculated. Simulations of the H+CH{sub 4} reaction based on the XCZ-NN PES show that the ZFWCZ PES predicts rate constants with reasonable highmore » accuracy for low temperatures while leads to slightly lower results for high temperatures, in line with the distribution of interpolation error associated with the ZFWCZ PES. The 8D H+CH{sub 4} rate constants derived on the ZFWCZ PES compare well with full-dimensional 12D results based on the equivalent m-ZFWCZ PES, with a maximum relative difference of no more than 20%. Additionally, very good agreement is shown by comparing the 8D XCZ-NN rate constants with the 12D results obtained on the ZFWCZ-WM PES, after considering the difference in static barrier height between these two PESs. The reaction rate constants calculated for the H{sub 2}+CH{sub 3} reaction are found to be in good consistency with experimental observations.« less

Encapsulating Quantum Dots into ZnO Nanorods for Advanced photonics and Laser Applications

DTIC Science & Technology

2016-10-12

nanotechnology , Nanofabrication 16.  SECURITY CLASSIFICATION OF: 17.  LIMITATION OF       ABSTRACT SAR 18.  NUMBER        OF        PAGES    15             19a...nanorods and microrods. Beilstein Journal of Nanotechnology , 2014. 5: p. 485-493. 2. Liu, J. and N. Motta, The nanonail flower. Materials Today...storage.(Review) Beilstein Journal of Nanotechnology 7: 149-196. (2016) 4. Mei Lyu, Jinzhang Liu, Jun Zhu⃰, Llew Rintoul, Nunzio Motta

A short note on the paper of Liu et al. (2012). A relative Lempel-Ziv complexity: Application to comparing biological sequences. Chemical Physics Letters, volume 530, 19 March 2012, pages 107-112

NASA Astrophysics Data System (ADS)

Arit, Turkan; Keskin, Burak; Firuzan, Esin; Cavas, Cagin Kandemir; Liu, Liwei; Cavas, Levent

2018-04-01

The report entitled "L. Liu, D. Li, F. Bai, A relative Lempel-Ziv complexity: Application to comparing biological sequences, Chem. Phys. Lett. 530 (2012) 107-112" mentions on the powerful construction of phylogenetic trees based on Lempel-Ziv algorithm. On the other hand, the method explained in the paper does not give promising result on the data set on invasive Caulerpa taxifolia in the Mediterranean Sea. The phylogenetic trees are obtained by the proposed method of the aforementioned paper in this short note.

Materials Research Society Symposium Proceedings Held in Boston, Massachusetts on 4-6 December 1991. Low Temperature (LT) GaAs and Related Materials. Volume 241.

DTIC Science & Technology

1992-09-14

AIGaAs-GaAs QUANTUM WELLS GROWN ON LOW TEMPERATURE GaAs 239 Y. Hwang, D. Zhang, T. Zhang, M. Mytych, and R.M. Kolbas MOLECULAR BEAM EPITAXY OF LOW...GaA/ quantum wells : 24i howvever, in our case. AIks layers were not introduced. Formation (if these rows is most prolf,.+l influenced hb the diffusimon...regions. Preliminary investigations into this method have been performed using GaAs quantum wells between thick AIGaAs barriers as shown in Fig. 7. This

Alpha-v Integrin Targeted PET Imaging of Breast Cancer Angiogenesis and Low-Dose Metronomic Anti-Angiogenic Chemotherapy Efficacy

DTIC Science & Technology

2006-08-01

64Cu -Labeled Abegrin™, a Humanized Monoclonal Antibody against Integrin αvβ3 Cancer Res. 2006;66(19):9673-81. 11. Hsu AR, Hou LC, Veeravagu A...FL, March, 2006. 5. Wu Y, Cai W, Zhang X, Chen K, Cao Q, Tice D, Chen X. In Vitro and In Vivo Characterization of 64Cu -Labeled Vitaxin, a...53rd SNM Annual meeting, San Diego, CA, June 2006 9. Cai W, Wu Y, Cao Q, Chen K, Zhang X, Tice D, Chen X 64Cu -Labeled Humanized Anti

Design Considerations for Monolithic Beam Formers Based on Electro-Optic Polymer Phase Modulators and Strain-Induced Optical Waveguides - Postprint

DTIC Science & Technology

2015-01-01

integrated circuit,” AFRL/SNDP Rome, NY (MIPR#F1ATA06317G002) (2007). [2] S-K. Kim, W. Yun, K. Geary, Y.-C. Hung, and H. R. Fetterman , “Electro-optic...Garner, H. Zhang, V. Chuyanov, L. R. Dalton, F. Wang, A. S. Ren, A. Zhang, G. Todorova, A. Harper, H. R. Fetterman , D. Chen, A. Upupa, D. Bhattacharya... Fetterman , “Push-pull electro-optic polymer modulators with half-wave voltage and low loss at both 1310 and 1550 nm,” Appl. Phys. Lett., 78, 3136-3138

Realization of New and Enhanced Materials Properties Through Nanostructural Control

DTIC Science & Technology

2006-05-15

34 Proc. SPIE, 6014, 60140P-1-15 (2005). 57. C. Zhang, S. S. Sun, C. E. Bonner, S. Kim, H. R. Fetterman , and L. R. Dalton, "Polymer Materials for...Wang, J. Zhu, M. He, Y. Ra, S. S. H. Mao, A. W. Harper, L. R. Dalton, and H. R. Fetterman , "Low Vn High Thermal Stability Electro Optic Polymer...H. Zhang, S. M. Garner, S. S. Lee, W. H. Steier, J. Chen, F. Wang, J. Zhu, M. He, Y. Ra, S. S. Mao, A. W. Harper, L. R. Dalton, and H. R. Fetterman

Retraction RETRACTION of "Tumor necrosis factor alpha gene -308G>A polymorphism association with the risk of esophageal cancer in a Han Chinese population" by H. Zhao, H.W. Zhang, T. Zhang and X.M. Gu - Genet. Mol. Res. 15 (2): gmr.15025866 DOI: http://dx.doi.org/10.4238/gmr.15025866.

PubMed

Zhao, H; Zhang, H W; Zhang, T; Gu, X M

2016-10-07

The retracted article is: Zhao H, Zhang HW, Zhang T and Gu XM (2016). Tumor necrosis factor alpha gene -308G>A polymorphism association with the risk of esophageal cancer in a Han Chinese population. Genet. Mol. Res. 15: gmr.15025866. Two major concerns were found in this article. Firstly, it was found to be substantially equal to the article "Tumor necrosis factor-alpha gene -308G > A polymorphism alters the risk of hepatocellular carcinoma in a Han Chinese population" published in the Diagnostic Pathology Diagnostic Pathology (2014) 9: 199, by Feng et al.; licensee BioMed Central. 2014 - DOI: 10.1186/s13000-014-0199-3. Secondly, the authors do not discuss limitations of their approaches in the discussion. The discussion is largely an elaboration of the literature in the introduction part. However, even in that context, the discussion does not appropriately review the literature and there are frequent references to conclusions that are not supported by the cited literature. The GMR editorial staff was alerted and after a thorough investigation, there is strong reason to believe that the peer review process was failure. Also, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract this article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.

A drug from poison: how the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered.

PubMed

Rao, Yi; Li, Runhong; Zhang, Daqing

2013-06-01

It is surprising that, while arsenic trioxide (ATO) is now considered as "the single most active agent in patients with acute promyelocytic leukemia (APL)", the most important discoverer remains obscure and his original papers have not been cited by a single English paper. The discovery was made during the Cultural Revolution when most Chinese scientists and doctors struggled to survive. Beginning with recipes from a countryside practitioner that were vague in applicable diseases, Zhang TingDong and colleagues proposed in the 1970s that a single chemical in the recipe is most effective and that its target is APL. More than 20 years of work by Zhang and colleagues eliminated the confusions about whether and how ATO can be used effectively. Other researchers, first in China and then in the West, followed his lead. Retrospective analysis of data from his own group proved that APL was indeed the most sensitive target. Removal of a trace amount of mercury chloride from the recipe by another group in his hospital proved that only ATO was required. Publication of Western replication in 1998 made the therapy widely accepted, though neither Western, nor Chinese authors of English papers on ATO cited Zhang's papers in the 1970s. This article focuses on the early papers of Zhang, but also suggests it worth further work to validate Chinese reports of ATO treatment of other cancers, and infers that some findings published in Chinese journals are of considerable value to patients and that doctors from other countries can benefit from the clinical experience of Chinese doctors with the largest population of patients.

Evaluation of NWP-based Satellite Precipitation Error Correction with Near-Real-Time Model Products and Flood-inducing Storms

NASA Astrophysics Data System (ADS)

Zhang, X.; Anagnostou, E. N.; Schwartz, C. S.

2017-12-01

Satellite precipitation products tend to have significant biases over complex terrain. Our research investigates a statistical approach for satellite precipitation adjustment based solely on numerical weather simulations. This approach has been evaluated in two mid-latitude (Zhang et al. 2013*1, Zhang et al. 2016*2) and three topical mountainous regions by using the WRF model to adjust two high-resolution satellite products i) National Oceanic and Atmospheric Administration (NOAA) Climate Prediction Center morphing technique (CMORPH) and ii) Global Satellite Mapping of Precipitation (GSMaP). Results show the adjustment effectively reduces the satellite underestimation of high rain rates, which provides a solid proof-of-concept for continuing research of NWP-based satellite correction. In this study we investigate the feasibility of using NCAR Real-time Ensemble Forecasts*3 for adjusting near-real-time satellite precipitation datasets over complex terrain areas in the Continental United States (CONUS) such as Olympic Peninsula, California coastal mountain ranges, Rocky Mountains and South Appalachians. The research will focus on flood-inducing storms occurred from May 2015 to December 2016 and four satellite precipitation products (CMORPH, GSMaP, PERSIANN-CCS and IMERG). The error correction performance evaluation will be based on comparisons against the gauge-adjusted Stage IV precipitation data. *1 Zhang, Xinxuan, et al. "Using NWP simulations in satellite rainfall estimation of heavy precipitation events over mountainous areas." Journal of Hydrometeorology 14.6 (2013): 1844-1858. *2 Zhang, Xinxuan, et al. "Hydrologic Evaluation of NWP-Adjusted CMORPH Estimates of Hurricane-Induced Precipitation in the Southern Appalachians." Journal of Hydrometeorology 17.4 (2016): 1087-1099. *3 Schwartz, Craig S., et al. "NCAR's experimental real-time convection-allowing ensemble prediction system." Weather and Forecasting 30.6 (2015): 1645-1654.

Bioinformatic analysis of the nucleotide binding site-encoding disease-resistance genes in foxtail millet (Setaria italica (L.) Beauv.).

PubMed

Zhu, Y B; Xie, X Q; Li, Z Y; Bai, H; Dong, L; Dong, Z P; Dong, J G

2014-08-28

The nucleotide-binding site (NBS) disease-resistance genes are the largest category of plant disease-resistance gene analogs. The complete set of disease-resistant candidate genes, which encode the NBS sequence, was filtered in the genomes of two varieties of foxtail millet (Yugu1 and 'Zhang gu'). This study investigated a number of characteristics of the putative NBS genes, such as structural diversity and phylogenetic relationships. A total of 269 and 281 NBS-coding sequences were identified in Yugu1 and 'Zhang gu', respectively. When the two databases were compared, 72 genes were found to be identical and 164 genes showed more than 90% similarity. Physical positioning and gene family analysis of the NBS disease-resistance genes in the genome revealed that the number of genes on each chromosome was similar in both varieties. The eighth chromosome contained the largest number of genes and the ninth chromosome contained the lowest number of genes. Exactly 34 gene clusters containing the 161 genes were found in the Yugu1 genome, with each cluster containing 4.7 genes on average. In comparison, the 'Zhang gu' genome possessed 28 gene clusters, which had 151 genes, with an average of 5.4 genes in each cluster. The largest gene cluster, located on the eighth chromosome, contained 12 genes in the Yugu1 database, whereas it contained 16 genes in the 'Zhang gu' database. The classification results showed that the CC-NBS-LRR gene made up the largest part of each chromosome in the two databases. Two TIR-NBS genes were also found in the Yugu1 genome.

Dependency distance in language evolution. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Liu, Bingli; Chen, Xinying

2017-07-01

In the target article [1], Liu et al. provide an informative introduction to the dependency distance studies and proclaim that language syntactic patterns, that relate to the dependency distance, are associated with human cognitive mechanisms, such as limited working memory and syntax processing. Therefore, such syntactic patterns are probably 'human-driven' language universals. Sufficient evidence based on big data analysis is also given in the article for supporting this idea. The hypotheses generally seem very convincing yet still need further tests from various perspectives. Diachronic linguistic study based on authentic language data, on our opinion, can be one of those 'further tests'.

Coevolution of dependency distance, hierarchical structure and word order. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Jing, Yingqi

2017-07-01

Exploring the relationships between structural rules and their linearization constraints have been a central issue in formal syntax and linguistic typology [1]. Liu et al. give a historical overview of the investigation of dependency distance minimization (DDM) in various fields, and specify its potential connections with the graphic patterns of syntactic structure and the linear ordering of words and constituents in real sentences [2]. This comment focuses on discussing the relations between dependency distance (DD), hierarchical structure and word order, and advocates further study on the coevolution of these traits in language histories.

A New Model of the Early Paleozoic Tectonics and Evolutionary History in the Northern Qinling, China

NASA Astrophysics Data System (ADS)

Dong, Yunpeng; Zhang, Guowei; Yang, Zhao; Qu, Hongjun; Liu, Xiaoming

2010-05-01

The Qinling Orogenic Belt extends from the Qinling Mountains in the west to the Dabie Mountains in the east. It lies between the North China and South China Blocks, and is bounded on the north by the Lushan fault and on the south by the Mianlue-Bashan-Xiangguang fault (Zhang et al., 2000). The Qinling Orogenic Belt itself is divided into the North and South Qinling Terranes by the Shangdan suture zone. Although the Shangdan zone is thought to represent the major suture separating the two blocks, there still exists debate about the timing and mechanism of convergence between these two blocks. For instance, some authors suggested an Early Paleozoic collision between the North China Block and South China Block (Ren et al., 1991; Kroner et al., 1993; Zhai et al., 1998). Others postulated left-lateral strike-slip faulting along the Shangdan suture at ca. 315 Ma and inferred a pre-Devonian collision between the two blocks (Mattauer et al., 1985; Xu et al., 1988). Geochemistry of fine-grained sediments in the Qinling Mountains was used to argue for a Silurian-Devonian collision (Gao et al., 1995). A Late Triassic collision has also been proposed (Sengor, 1985; Hsu et al., 1987; Wang et al., 1989), based on the formation of ultrahigh-pressure metamorphic rocks in the easternmost part of the Qinling Orogenic Belt at ~230 Ma (e.g., Li et al., 1993; Ames et al., 1996). Paleomagnetic data favor a Late Triassic-Middle Jurassic amalgamation of the North China and South China Blocks (Zhao and Coe, 1987; Enkin et al., 1992). It is clear that most authors thought that the Qinling Mountains are a collisional orogen, even they have different methods about the timing of the orogeny. Based on new detailed investigations, we propose a new model of the Early Paleozoic Tectonics and Evolutionary History between the North China and South China Blocks along the Shangdan Suture. The Shangdan suture is marked by a great number of ophiolites, island-arc volcanic rocks and other related rock assemblages. Our new geological and geochemical data revealed a lot of ophiolitic mélanges along the Shangdan suture, such as the Guojiagou, Ziyu, Xiaowangjian, Yanwan, Tangzang, Guanzizhen and Wushan areas from east to west. The ophiolite assemblage in Guojiagou, Ziyu area consists mainly of some blocks of E-MORB type and IAB-type basalts, while the pillow lavas from Xiaowangjian are IAB-type basalts. The basalts from the ophiolite assemblages in Yanwan, Tangzang and Wushan areas possess E-MORB geochemical compositions. The zircons of gabbro from Yanwan ophiolite mélange yield an U-Pb age of 516±3.8 Ma, which represents the formation age of the Yanwan ophiolite. Meanwhile, the basalts in the Guanzizhen ophiolite mélange show N-MORB type geochemical signature, and the zircons from gabbro yield a U-Pb age of 471±1.4 Ma, which constraints the formation age of the mature oceanic crust. Additionally, there also exists a U-Pb age of 523±26 Ma (Lu et al.,2003) and Cambrian-Ordovician radiolarites from the interlayed silicarites within the volcanic rock in the Guojiagou ophiolite mélange (Cui et al., 1995). All these geochemical and geochronological evidences indicate that there existed an oceanic basin and its subduction, which separated the Northern China Block from the Southern China Block during 523 -471 Ma. Accordant with this ocean and its subduction, there had been existed an active continental margin, island-arc setting on the north side of the Shangdan ophiolite mélange which were marked by a series of moderate-basic intrude igneous mass along the Sifangtai-Lajimiao area (Li et al., 1993) and the Fushui area (Dong et al., 1997). In addition to, there also exist a great number of subduction-collisional granites intruding into island-arc basement along the active continental margin. Zircons from the Fushui intrusion yield a U-Pb age of 514±1.3 Ma (Chen et al., 2004), which constraints the time of the subduction. Above all, more and more data suggest that there exists a back-arc basin on the northern side of the island-arc terrain. To the east, it is presented by the Erlangping group in Xixia area, which consists mainly of clastic sediments, carbonatites and basic volcanic rocks. The geochemistry of the basalts show that they were formed in a back-arc basin setting (Sun et al.,1996), and the radiolarites from the interlayed silicalites show the Orovician-Silurian age (Wang et al., 1995). Our new investigation reveals some new tectonic assemblages exposed in the Yinggerzui area, Qinghusi area to the west. The detailed geochemical studies indicate that they were formed in a back-arc basin. All above evidences suggest that there had existed an Early Paleozoic subduction system, which consists of a subduction trench, island-Arc and back-arc basin along the northern Qinling zone. It is also indicated that the Paleo-ocean had been evolved into a complete evolutionary process including initial spreading (E-MORB ophiolite), maturated extension (N-MORB ophiolite) and subduction (Island-arc volcanic rocks). However, it is notable that there are large scale of Devonian clastic sediments distributing on the south of the Shangdan suture, and the pre-Mesozoic rocks in the South Qinling without any metamorphism or just underwent the low-greenschist facies metamorphism in some places, which are very different from the North Qinling Terrane consisting mainly of Precambrian rocks and evolving into an amphibolite facies metamorphism at ~1.0 Ga and greenschist facies metamorphism at ~400 Ma (Liu et al., 1993; Zhang et al., 1994). Accordingly, it is prefer that there only occurred a subduction of the Shangdan oceanic crust from south to north along the Shangdan suture on the south of the Northern Qinling Terrane. However, the Piaochi and the Anjiping granites possessing the sym-collisional type granite geochemistry and formation age of 450-486 (Chen et al., 1991; zhang et al., 1996) indicate that there occurred a collisional event between the North Qinling Island-arc Terrane and the Northern China Block caused by closing of the Early Paleozoic back-arc basin. Additionally, the studies of the metamorphism show that there are two zones of high / ultra-high pressure metamorphic rocks outcropping along the both side of the Northern Qingling island-arc terrane. On the north, it is characterized by eclogite and coesite outcropping in the Guanpo area, and the metamorphic zircon U-Pb age of 507±38 Ma and 509±12 Ma by means of SHRIM (Yang et al., 2002). Meanwhile, there also exist some high pressure basic granulite (Liu et al., 1995) and felsic granulite (Liu et al., 1996) distributing in the Xigou fault on the south margin of the Northern Qingling island-arc terrane. Zircon U-Pb ages of 485±3.3 Ma by means of LA－ICP－MS method (Chen et al., 2004) and 518±12 Ma by means of SHRIM (Liu et al., 2003) constrain the time of the metamorphism. All these metamorphic data suggest the Northern Qingling island-arc terrane had been evolved into a deep subduction event during 485-518 Ma. Based on all above evidences, we infer a new model about the tectonics and evolutionary history of the Norhtern Qinling Terrane. It is emphasized that the Early Paleozoic tectonics between the North China and Southern China Blocks had existed an ocean, island-arc and back-arc basin, and evolved into four stages of evolutionary stages: 1) initial spreading along the Shangdan zone during 516-523 Ma; 2) maturated ocean along the Shangdan zone during 516-471 Ma; 3) subduction along the south side of the Northern Qinling Terrane and formation of the Back-arc basin along the north side of the Northern Qinling Terrane during518-514; 4) closing of the back-arc basin, collision between the Northern Qingling island-arc terrane and the Northern China Block, and deep subduction of the Northern Qingling island-arc terrane during 518-485Ma. This work was supported by NSFC (40772140 & 40972140)

Direct discontinuous Galerkin method and its variations for second order elliptic equations

DOE PAGES

Huang, Hongying; Chen, Zheng; Li, Jin; ...

2016-08-23

In this study, we study direct discontinuous Galerkin method (Liu and Yan in SIAM J Numer Anal 47(1):475–698, 2009) and its variations (Liu and Yan in Commun Comput Phys 8(3):541–564, 2010; Vidden and Yan in J Comput Math 31(6):638–662, 2013; Yan in J Sci Comput 54(2–3):663–683, 2013) for 2nd order elliptic problems. A priori error estimate under energy norm is established for all four methods. Optimal error estimate under L 2 norm is obtained for DDG method with interface correction (Liu and Yan in Commun Comput Phys 8(3):541–564, 2010) and symmetric DDG method (Vidden and Yan in J Comput Mathmore » 31(6):638–662, 2013). A series of numerical examples are carried out to illustrate the accuracy and capability of the schemes. Numerically we obtain optimal (k+1)th order convergence for DDG method with interface correction and symmetric DDG method on nonuniform and unstructured triangular meshes. An interface problem with discontinuous diffusion coefficients is investigated and optimal (k+1)th order accuracy is obtained. Peak solutions with sharp transitions are captured well. Highly oscillatory wave solutions of Helmholz equation are well resolved.« less

Direct discontinuous Galerkin method and its variations for second order elliptic equations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Hongying; Chen, Zheng; Li, Jin

In this study, we study direct discontinuous Galerkin method (Liu and Yan in SIAM J Numer Anal 47(1):475–698, 2009) and its variations (Liu and Yan in Commun Comput Phys 8(3):541–564, 2010; Vidden and Yan in J Comput Math 31(6):638–662, 2013; Yan in J Sci Comput 54(2–3):663–683, 2013) for 2nd order elliptic problems. A priori error estimate under energy norm is established for all four methods. Optimal error estimate under L 2 norm is obtained for DDG method with interface correction (Liu and Yan in Commun Comput Phys 8(3):541–564, 2010) and symmetric DDG method (Vidden and Yan in J Comput Mathmore » 31(6):638–662, 2013). A series of numerical examples are carried out to illustrate the accuracy and capability of the schemes. Numerically we obtain optimal (k+1)th order convergence for DDG method with interface correction and symmetric DDG method on nonuniform and unstructured triangular meshes. An interface problem with discontinuous diffusion coefficients is investigated and optimal (k+1)th order accuracy is obtained. Peak solutions with sharp transitions are captured well. Highly oscillatory wave solutions of Helmholz equation are well resolved.« less

Augmented Hebbian reweighting accounts for accuracy and induced bias in perceptual learning with reverse feedback

PubMed Central

Liu, Jiajuan; Dosher, Barbara Anne; Lu, Zhong-Lin

2015-01-01

Using an asymmetrical set of vernier stimuli (−15″, −10″, −5″, +10″, +15″) together with reverse feedback on the small subthreshold offset stimulus (−5″) induces response bias in performance (Aberg & Herzog, 2012; Herzog, Eward, Hermens, & Fahle, 2006; Herzog & Fahle, 1999). These conditions are of interest for testing models of perceptual learning because the world does not always present balanced stimulus frequencies or accurate feedback. Here we provide a comprehensive model for the complex set of asymmetric training results using the augmented Hebbian reweighting model (Liu, Dosher, & Lu, 2014; Petrov, Dosher, & Lu, 2005, 2006) and the multilocation integrated reweighting theory (Dosher, Jeter, Liu, & Lu, 2013). The augmented Hebbian learning algorithm incorporates trial-by-trial feedback, when present, as another input to the decision unit and uses the observer's internal response to update the weights otherwise; block feedback alters the weights on bias correction (Liu et al., 2014). Asymmetric training with reversed feedback incorporates biases into the weights between representation and decision. The model correctly predicts the basic induction effect, its dependence on trial-by-trial feedback, and the specificity of bias to stimulus orientation and spatial location, extending the range of augmented Hebbian reweighting accounts of perceptual learning. PMID:26418382

Augmented Hebbian reweighting accounts for accuracy and induced bias in perceptual learning with reverse feedback.

PubMed

Liu, Jiajuan; Dosher, Barbara Anne; Lu, Zhong-Lin

2015-01-01

Using an asymmetrical set of vernier stimuli (-15″, -10″, -5″, +10″, +15″) together with reverse feedback on the small subthreshold offset stimulus (-5″) induces response bias in performance (Aberg & Herzog, 2012; Herzog, Eward, Hermens, & Fahle, 2006; Herzog & Fahle, 1999). These conditions are of interest for testing models of perceptual learning because the world does not always present balanced stimulus frequencies or accurate feedback. Here we provide a comprehensive model for the complex set of asymmetric training results using the augmented Hebbian reweighting model (Liu, Dosher, & Lu, 2014; Petrov, Dosher, & Lu, 2005, 2006) and the multilocation integrated reweighting theory (Dosher, Jeter, Liu, & Lu, 2013). The augmented Hebbian learning algorithm incorporates trial-by-trial feedback, when present, as another input to the decision unit and uses the observer's internal response to update the weights otherwise; block feedback alters the weights on bias correction (Liu et al., 2014). Asymmetric training with reversed feedback incorporates biases into the weights between representation and decision. The model correctly predicts the basic induction effect, its dependence on trial-by-trial feedback, and the specificity of bias to stimulus orientation and spatial location, extending the range of augmented Hebbian reweighting accounts of perceptual learning.

Imprecise intron losses are less frequent than precise intron losses but are not rare in plants.

PubMed

Ma, Ming-Yue; Zhu, Tao; Li, Xue-Nan; Lan, Xin-Ran; Liu, Heng-Yuan; Yang, Yu-Fei; Niu, Deng-Ke

2015-05-27

In this study, we identified 19 intron losses, including 11 precise intron losses (PILs), six imprecise intron losses (IILs), one de-exonization, and one exon deletion in tomato and potato, and 17 IILs in Arabidopsis thaliana. Comparative analysis of related genomes confirmed that all of the IILs have been fixed during evolution. Consistent with previous studies, our results indicate that PILs are a major type of intron loss. However, at least in plants, IILs are unlikely to be as rare as previously reported. This article was reviewed by Jun Yu and Zhang Zhang. For complete reviews, see the Reviewers' Reports section.

Organization of the Optical Society of America Photonic Science Topical Meeting Series (1991). Volume 16. Conference Edition: Summaries of papers presented at the Persistent Spectral Hole-Burning: Science and Applications Topical Meeting Held in Monterey, California on 26-28 September 1991

DTIC Science & Technology

1992-05-22

Duoyuan Wang, Lingzhi Hu, Huizhu He, Jie Xie, 532 nm. (p. 122) Junyl Zhang, Academy of Sciences of China. Photon-gated persistent spectral hole...hole-burning, Duoyuan VWang, Lingzhi Hu, Huizhu He, Lizeng Zhao, Xin Mi, Yuxin Ni, Academy of Sciences, China. FE5 Marker mode structure in the primary...Xiulang, Zhang Dongxiang, Mi Xin, Nie Yuxin Institute of Physics, Academia Sinica Beijing 100080, China, Fax:(86-1)2562605 Wang Duoyuan, Hu Lingzhi , He

Earthquakes & Tsunamis flirting with the Ionosphere: the Sumatra gossip !!

NASA Astrophysics Data System (ADS)

Occhipinti, G.; Coïsson, P.; Rolland, L. M.; Lognonne, P.

2009-12-01

The December 26, 2004 Sumatra Earthquake and the related Indian Ocean Tsunami generated the largest remote sensing data-set observing natural hazards. The observations showed both, ground motion and ocean sea surface displacement, as well as the related strong ionospheric anomalies. Total electron content (TEC) perturbations have been observed on a global scale, using ground-based GPS receivers [DasGupta et al., 2006, Liu et al., 2006b] and dual-frequency altimeters (e.g., Jason-1 and Topex/Poseidon [Artru et al., 2005]); plasma velocity perturbation has been observed by Doppler soundings [Liu et al., 2006b, Occhipinti et al., 2009]. The observed perturbations may be characterized as two different waves: the first one is an atmospheric wave in the acoustic domain induced by propagation of Rayleigh waves on the Earth surface; the second one is a slower atmospheric wave in the gravity domain strongly coupled with the generated tsunami. Both waves are reproduced by our accurate modeling taking into account the earthquake/tsunami-neutral atmosphere coupling at the base of the atmosphere, as well as the neutral-plasma coupling in the overlying ionosphere [Occhipinti et al., 2006, 2006, 2009]. Here we present a review of the ionospheric observations related to the Sumatra event in the light of modeling to deeply investigate the coupling mechanism between Solid-Earth/Ocean/Atmosphere/Ionosphere. The matching between data and modeling opens new perspectives in the solid earth research as well as in the tsunami detection providing a new insight into the role of the remote sensing in the monitoring of natural hazard. [Artru et al., 2005] Geophys. J. Int., 160, 2005 [DasGupta et al., 2006] Earth Planet. Space, 35, 929-959. [Liu et al., 2006a] Geophys. Res. Lett., 33, L02103, 2006. [Liu et al., 2006b] J. Geophys. Res., 111, A05303. [Occhipinti et al., 2006] Geophys. Res. Lett., 33, L20104, 2006 [Occhipinti et al., 2008] Geophys. J. Int., 173, 3, 753-1135, 2008. [Occhipinti et al., 2009] Geophys. Res. Lett., under review

Efficacy of modified LiuJunZi decoction on functional dyspepsia of spleen-deficiency and qi-stagnation syndrome: a randomized controlled trial

PubMed Central

2013-01-01

Background Chinese herbal medicine (CHM) has been used in China and some other countries for the treatment of patients with functional dyspepsia (FD). However, controlled studies supporting the efficacy of such treatments in patients with FD are lacking. In this trial, we aimed to assess the efficacy and safety of modified LiuJunZi decoction in patients with FD of spleen-deficiency and qi-stagnation syndrome. Methods We performed a randomized, double-blind, placebo-controlled trial with patients from five centers. Patients with FD of spleen-deficiency and qi-stagnation syndrome (n = 160) were randomly assigned to groups given CHM modified LiuJunZi decoction or placebo in a 2:1 ratio. Herbal or placebo granules were dissolved in 300 ml of boiled water cooled to 70°C. Patients in both groups were administered 150 ml (50°C) twice daily. The trial included a 4-week treatment period and a 4-week follow-up period. The primary outcomes were dyspepsia symptom scores, measured by the total dyspepsia symptom scale and the single dyspepsia symptom scale at weeks 0, 1, 2, 3, 4 and 8. The secondary outcome was the change of radiopaque barium markers emptied from the stomach between week 0 and week 4 of treatment. Results Compared with patients in the placebo group, patients in the CHM group showed significant improvements according to the scores of total dyspepsia symptoms and single dyspepsia symptoms obtained from patients (P < 0.01) and investigators (P < 0.01). They also showed an improvement in the number of radiopaque barium markers emptied from the stomach (P < 0.05). Conclusions CHM modified LiuJunZi decoction appears to offer symptomatic improvement in patients with FD of spleen-deficiency and qi-stagnation syndrome. Trial registration Chinese Clinical Trial Registry (ChiCTR): http://ChiCTR-TRC-10001074 PMID:23453018

Effects of Improving Primary Health Care Workers' Knowledge About Public Health Services in Rural China: A Comparative Study of Blended Learning and Pure E-Learning.

PubMed

Zhan, Xingxin; Zhang, Zhixia; Sun, Fang; Liu, Qian; Peng, Weijun; Zhang, Heng; Yan, Weirong

2017-05-01

Primary health care workers (PHCWs) are a major force in delivering basic public health services (BPHS) in rural China. It is necessary to take effective training approaches to improve PHCWs' competency on BPHS. Both electronic learning (e-learning) and blended learning have been widely used in the health workers' education. However, there is limited evidence on the effects of blended learning in comparison with pure e-learning. The aim of this study was to evaluate the effects of a blended-learning approach for rural PHCWs in improving their knowledge about BPHS as well as training satisfaction in comparison with a pure e-learning approach. The study was conducted among PHCWs in 6 rural counties of Hubei Province, China, between August 2013 and April 2014. Three counties were randomly allocated blended-learning courses (29 township centers or 612 PHCWs-the experimental group), and three counties were allocated pure e-learning courses (31 township centers or 625 PHCWs-the control group). Three course modules were administered for 5 weeks, with assessments at baseline and postcourse. Primary outcomes were score changes in courses' knowledge. Secondary outcome was participant satisfaction (5-point Likert scale anchored between 1 [strongly agree] and 5 [strongly disagree]). The experimental group had higher mean scores than the control group in knowledge achievement in three course modules: (1) module 1: 93.21 (95% CI 92.49-93.93) in experimental group versus 88.29 (95% CI 87.19-89.40) in the control group; adjusted difference, 4.92 (95% CI 2.61-7.24; P<.001); (2) module 2: 94.05 (95% CI 93.37-94.73) in the experimental group vs 90.22 (95% CI 89.12-91.31) in the control group; adjusted difference, 3.67 (95% CI 1.17-6.18; P=.004); (3) module 3: 93.88 (95% CI 93.08-94.68) in the experimental group versus 89.09 (95% CI 87.89-90.30) in control group; adjusted difference, 4.63 (95% CI 2.12-7.14; P<.001). The participants in the experimental learning group gave more positive responses with the four issues than control group participants: (1) the increase of interest in learning, 1.85 (95% CI 1.22-2.80; P=.003); (2) the increase of interaction with others, 1.77 (95% CI 1.20-2.60; P=.004); (3) the satisfaction with learning experience, 1.78 (95% CI 1.11-2.88; P=.02); and (4) achievement of learning objectives, 1.63 (95% CI 1.08-2.48; P=.02). Among PHCWs in rural China, a blended-learning approach to BPHS training could result in a higher knowledge achievement and satisfaction level compared with a pure e-learning approach. The findings of the study will contribute knowledge to improve the competency of PHCWs in similar settings. ©Xingxin Zhan, Zhixia Zhang, Fang Sun, Qian Liu, Weijun Peng, Heng Zhang, Weirong Yan. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 01.05.2017.

Structure, Behavior, Function as a Framework For Teaching and Learning about Complexity In Ecosystems: Lessons from Middle School Classrooms (Invited)

NASA Astrophysics Data System (ADS)

Hmelo-Silver, C.; Gray, S.; Jordan, R.

2010-12-01

Complex systems surround us, and as Sabelli (2006) has argued, understanding complex systems is a critical component of science literacy. Understanding natural and designed systems are also prominent in the new draft science standards (NRC, 2010) and therefore of growing importance in the science classroom. Our work has focused on promoting an understanding of one complex natural system, aquatic ecosystems, which given current events, is fast becoming a requisite for informed decision-making as citizens (Jordan et al. 2008). Learners have difficulty understanding many concepts related to complex natural systems (e.g., Hmelo-Silver, Marathe, & Liu, 2007; Jordan, Gray, Liu, Demeter, & Hmelo-Silver, 2009). Studies of how students think about complex ecological systems (e.g; Hmelo-Silver, Marathe, & Liu, 2007; Hogan, 2000, Hogan & Fisherkeller, 1996: Covitt & Gunkel, 2008) have revealed difficulties in thinking beyond linear flow, single causality, and visible structure. Helping students to learn about ecosystems is a complex task that requires providing opportunities for students to not only engage directly with ecosystems but also with resources that provide relevant background knowledge and opportunities for learners to make their thinking visible. Both tasks can be difficult given the large spatial and temporal scales on which ecosystems operate. Additionally, visible components interact with often invisible components which can obscure ecosystem processes for students. Working in the context of aquatic ecosystems, we sought to provide learners with representations and simulations that make salient the relationship between system components. In particular, we provided learners with opportunities to experience both the micro-level and macro-level phenomena that are key to understanding ecosystems (Hmelo-Silver, Liu, Gray, & Jordan, submitted; Liu & Hmelo-Silver, 2008; Jacobson & Wilensky, 2006). To accomplish this, we needed to help learners make connections across the levels of ecosystems. A big part of this is making phenomena accessible to their experience. We accomplished through the use of physical models and computers simulations at different scale. In an effort to promote a coherent understanding in our learners, we sought to develop tools that can provide dynamic feedback that will enable them to modify, enrich, and repair their mental models as needed (e.g., Roschelle, 1996). Additionally, we also wanted to develop a conceptual representation that can be used across multiple ecosystems to prepare students to learn about new systems in the future (Bransford & Schwartz, 1999). Our approach to this has been to use the structure-behavior-function (SBF) conceptual representation (Liu & Hmelo-Silver, 2009; Vattam et al., in press). Often, learning life science is about learning the names of structures. One of our design principles is to ensure instruction emphasizes the behaviors (or mechanisms) of systems as well as the functions (the system outputs) in addition to the structures. We have used simulations to help make behaviors and functions visible and a modeling tool that supports students in thinking about the SBF conceptual representation. In this presentation, we will report on the results of classroom interventions and the lessons learned.

Manufacturing Technology.

ERIC Educational Resources Information Center

Liu, Yuan H.; And Others

1994-01-01

Includes "Integrating Coursework in Design with Industry Projects" (Liu); "A 'Perfect' Project--Computer Assisted Manufacturing, Fabrication, and Recycling All in One" (Anderson); and "Fluid Sensing and Control" (Hawkins, Hardy). (SK)

Economic wealth and soil erosion in new Citrus plantations in Eastern Spain or how to explain the Land Degradation

NASA Astrophysics Data System (ADS)

Giménez-Morera, Antonio; Cerdà, Artemio; Pereira, Pauloq

2014-05-01

We use to accept the idea that the best oranges are coming from Valecia Region in Eastern Spain. Although the oranges are originally from Eastern Asia, Valencia is having a mild climate in winter, with a low recurrency of frost and is strategically located close to the largest market of citrus: Western Europe. This resulted in a continuous growth of production and trade of citrus, and contributed to make the Valencia Region the largest World exporter (Bono, 2010). This economical success reached the highest point after the EU and Spain agreement in 1986. This expansion of citrus plantations were done on steep slopes allowed by the drip irrigation systems that does not need leveling the land as it was done by new farmers with large properties. The traditional farming of oranges was done in small properties, flood irrigation and leveled land. Those changes are triggering intense soil erosion rates such were shown by previous researchers in Valencia (Cerdà et al., 2009). This impact is also shown in other regions with a similar citrus production evolution, and China is a clear example (Wang et al., 2010; Liu et al., 2012). Land This research evaluate the relations between the investment (economic wealth) of the owners of citrus plantations and the soil erosion rates on their orchards. The economic wealth of the onwers was measured on the size of their properties and after an interview. The soil erosion rates were measured by means of rainfall simulation experiments in each farm by means of thunderstorms of 10 years return period (55 mm h-1). The results show that the soil losses in the new plantations are extremely high (> 10 Mg ha-1 y-1), and that we can show three types of orchards: < 0.99 ha; 1-10 ha and > 10.1. The soil erosion rates where positively related to the size of the farms. The higher erosion rates are shown also by the scientific literature review. Chemically treated plantations (Cerdà, 2002) show high erosion rates due to the road construction too (Cerdà, 2007) and is higher than rainfed agriculture soil (García Orenes et al., 2009). Acknowledgements The research projects GL2008-02879/BTE, LEDDRA 243857 and RECARE FP7 project 603498 supported this research. References Bono, E. 2010. Naranja y desarrollo. La base agrícola exportadora de la economía del País Valenciano y el modelo de crecimiento hacea afuera. PUV, Valencia, 203 pp. Cerdà, A. 2001. Erosión hídrica del suelo en el Territorio Valenciano. El estado de la cuestión a través de la revisión bibliográfica. Geoforma Ediciones, Logroño, 79 pp. Cerdá, A. 2007. Soil water erosion on road embankments in Eastern Spain. Science of the Total Environments 378, 151-155. Cerdà, A., Morera, A.G., Bodí, M.B. 2009. Soil and water losses from new citrus orchards growing on sloped soils in the western Mediterranean basin. Earth Surface Processes and Landforms, 34 (13), 1822-1830. García-Orenes, F., Cerdà, A., Mataix-Solera, J., Guerrero, C., Bodí, M.B., Arcenegui, V., Zornoza, R. & Sempere, J.G. 2009. Effects of agricultural management on surface soil properties and soil-water losses in eastern Spain. Soil and Tillage Research, doi:10.1016/j.still.2009.06.002 Liu, Y., Tao, Y., Wan, K.Y., Zhang, G.S., Liu, D.B., Xiong, G.Y., Chen, F. 2012. Runoff and nutrient losses in citrus orchards on sloping land subjected to different surface mulching practices in the Danjiangkou Reservoir area of China. Agricultural Water Management, 110, 34-40. Wang, L., Tang, L., Wang, X., Chen, F. 2010. Effects of alley crop planting on soil and nutrient losses in the citrus orchards of the Three Gorges Region. Soil and Tillage Research, 110 (2), 243-250.

Revisiting syntactic development in deaf and hearing children from a dependency approach. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Yan, Jingqi

2017-07-01

Linguists are always endeavoring to discover universal rules to explain the language phenomena and interrelations [1]. Through a handful of corpus-based studies and a vast body of supporting evidence from psychological experiments, Liu, Xu and Liang [2] arrive at a conclusion on a general tendency toward dependency distance minimization (DDM) and relate this linguistic universal to the constraints of memory. Dependency distance (DD) is hereby introduced as a linguistic property, with quantitative features of frequency, and profound cognitive grounding as well. However, since the authors do not include language development, in this comment, I would like to discuss some future prospects from this perspective.

Depression, delinquency, and suicidal behaviors among college students.

PubMed

Bauer, Rebecca L; Chesin, Megan S; Jeglic, Elizabeth L

2014-01-01

Liu (2004) investigated the interaction between delinquency and depression among adolescents and found that delinquency moderated the relationship between depression and suicidal behaviors. This study also explored the relationship between depression, delinquency, and suicidal behaviors, although delinquency was expected to mediate, as opposed to moderate, the relationship between depression and suicidal behaviors. The participants comprised 354 college students. The students completed a series of questionnaires measuring delinquent behavior, depressive symptoms, and suicidal thoughts and behaviors. Contrary to Liu's (2004) findings, delinquency was found not to moderate but rather to partially mediate the relationship between depression and suicidal behaviors. The findings suggest that for some college students, depression is associated with delinquent behaviors, which, in turn, are associated with suicidal behaviors.

Kardar-Parisi-Zhang universality in the phase distributions of one-dimensional exciton-polaritons

NASA Astrophysics Data System (ADS)

Squizzato, Davide; Canet, Léonie; Minguzzi, Anna

2018-05-01

Exciton-polaritons under driven-dissipative conditions exhibit a condensation transition that belongs to a different universality class from that of equilibrium Bose-Einstein condensates. By numerically solving the generalized Gross-Pitaevskii equation with realistic experimental parameters, we show that one-dimensional exciton-polaritons display fine features of Kardar-Parisi-Zhang (KPZ) dynamics. Beyond the scaling exponents, we show that their phase distribution follows the Tracy-Widom form predicted for KPZ growing interfaces. We moreover evidence a crossover to the stationary Baik-Rains statistics. We finally show that these features are unaffected on a certain timescale by the presence of a smooth disorder often present in experimental setups.

Prescription Pattern of Chinese Herbal Products for Diabetes Mellitus in Taiwan: A Population-Based Study

PubMed Central

Huang, Chung-Yu; Lai, Jung-Nien; Hsu, Feng-Lin

2013-01-01

Background. Traditional Chinese medicine (TCM), when given as a therapy for symptom relief, has gained widespread popularity among diabetic patients. The aim of this study is to analyze the utilization of TCM among type 2 diabetic patients in Taiwan. Methods. The use of TCM for type 2 diabetic patients were evaluated using a randomly sampled cohort of 1,000,000 beneficiaries recruited from the National Health Insurance Research Database. Results. Overall, 77.9% (n = 31,289) of type 2 diabetic patients utilized TCM and 13.9% (n = 4,351) of them used TCM for the treatment of type 2 diabetes. Among the top ten most frequently prescribed herbal formulae, four remedies, Zhi-Bo-Di-Huang-Wan, Qi-Ju-Di-Huang-Wan, Ji-Sheng-Shen-Qi-Wan and Ba-Wei-Di-Huang-Wan are derivative formulae of Liu-Wei-Di-Huang-Wan. In other words, Liu-Wei-Di-Huang-Wan and its derivatives were found to be the most common herbal formulae prescribed by TCM doctors for the treatment of diabetes in Taiwan. Conclusion. Although some evidence does support the use TCM to treat diabetes, the results from the current study may have been confounded by placebo effect, which emphasize the need for well conducted, double-blind, randomized, placebo-controlled studies in order to further evaluate the efficacy of Liu-Wei-Di-Huang-Wan on patients with type 2 diabetes. PMID:23843864

Secondary electron emission from plasma-generated nanostructured tungsten fuzz

DOE PAGES

Patino, M.; Raitses, Y.; Wirz, R.

2016-11-14

Recently, several researchers (e.g., Q. Yang, Y.-W. You, L. Liu, H. Fan, W. Ni, D. Liu, C. S. Liu, G. Benstetter, and Y. Wang, Scientific Reports 5, 10959 (2015)) have shown that tungsten fuzz can grow on a hot tungsten surface under bombardment by energetic helium ions in different plasma discharges and applications, including magnetic fusion devices with plasma facing tungsten components. This work reports direct measurements of the total effective secondary electron emission (SEE) from tungsten fuzz. Using dedicated material surface diagnostics and in-situ characterization, we find two important results: (1) SEE values for tungsten fuzz are 40-63% lowermore » than for smooth tungsten and (2) the SEE values for tungsten fuzz are independent of the angle of the incident electron. The reduction in SEE from tungsten fuzz is most pronounced at high incident angles, which has important implications for many plasma devices since in a negative-going sheath the potential structure leads to relatively high incident angles for the electrons at the plasma confining walls. Overall, low SEE will create a relatively higher sheath potential difference that reduces plasma electron energy loss to the confining wall. Thus the presence or self-generation in a plasma of a low SEE surface such as tungsten fuzz can be desirable for improved performance of many plasma devices.:7px« less

Pseudopotential Computations for Metal/Alumina Interfaces

NASA Astrophysics Data System (ADS)

Zhang, Wenqing

2003-03-01

Metal/alumina interfaces are found, for example, in electronic devices, as thermal barrier coatings in gas turbines, and in coatings to inhibit corrosion and wear. Of particular importance to their performance is their adhesion. Ultrasoft pseudopotentials combined with plane wave methods and density-functional theory have been employed to compute the properties of these relatively complex interfaces, including effects of impurity segregation. Interfacial stoichiometry and impurity content affect interfacial properties importantly. Thermodynamic links between our first principles results and metallurgical variables such as oxygen activity and oxygen partial pressure are established. This allows for a comparison between theoretical predictions and experimental measurements. Good agreement is obtained for predicted interfacial variables such as atomic structure and adhesive bond strengths on comparison with results of sessile drop, fracture, and other experiments on interfaces of Ni, Cu, Al, and Ag with alumina [1-3], including effects of water and sulfur interfacial impurities. Understanding of the nature of the adhesive bonding at the atomic level is obtained by the pseudopotential first principles approach. [1] W.Zhang, and J.R.Smith, and A.G.Evans, Acta Mater., 50,3803(2002). [2] W.Zhang, and J.R.Smith, Phys. Rev. Lett. 85, 3225(2000). [3] W.Zhang, and J.R.Smith, Phys. Rev. B61, 16883(2000).

Mitochondrial Replacement Techniques, Scientific Tourism, and the Global Politics of Science.

PubMed

Chan, Sarah; Palacios-González, César; De Jesús Medina Arellano, María

2017-09-01

The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom as the most likely location for the first MRT birth, so it was a shock when, on September 27, 2016, an announcement went out that the first baby to result from use of the intervention had already been born. In New York City, United States-based scientist John Zhang used maternal spindle transfer (one of the recognized MRT methods) to generate five embryos for a woman carrying oocytes with deleterious mutations of the mitochondrial DNA. Zhang then shipped the only euploid embryo to Mexico, where it was transferred to the mother's uterus. Zhang's team's travel across international borders to carry out experimental procedures represents a form of scientific tourism that has not been properly ethically explored; it can, however, have seriously detrimental effects for developing countries. © 2017 The Hastings Center.

Reply to the comment by Q.Q. Qiao et al. on ;Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression; by Tao Zhang, Xiaomin Fang, Chunhui Song, Erwin Appel, and Yadong Wang [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044

NASA Astrophysics Data System (ADS)

Zhang, Tao; Fang, Xiaomin; Song, Chunhui; Appel, Erwin; Wang, Yadong

2017-07-01

Qiao et al. (2016) commented on our work (Zhang et al., 2014) and rejected our reinterpretation of the magnetostratigraphic results of Huang et al. (2006) and Li et al. (2006), with the results gained using the Dynamic Time Warping Algorithm technique (DTWAT) as their main basis. However, Qiao et al. (2016) did not provide details of their modeling inputs, and, in particular, the parameters they chose for their calculations, where such parameters can have a serious impact upon any results. We therefore performed calculations using the same software (i.e., Qupydon) as Qiao et al. (2016), using reliable parameter settings. The results showed that the ;interesting correlation; of a 6000 minimum cost output completely correlate with the magnetostratigraphic Chrons C18r to C3An.1n ( 40-6 Ma), which is consistent with our reinterpreted magnetostratigraphic results. Furthermore, we summarized previous biostratigraphic studies of nearby areas; the data resulting from this process also supported our reinterpreted magnetostratigraphic correlation. We were therefore able to confirm the revised magnetostratigraphic correlation of Zhang et al. (2014).

Preliminary results of strong ground motion simulation for the Lushan earthquake of 20 April 2013, China

NASA Astrophysics Data System (ADS)

Zhu, Gengshang; Zhang, Zhenguo; Wen, Jian; Zhang, Wei; Chen, Xiaofei

2013-08-01

The earthquake occurred in Lushan County on 20 April, 2013 caused heavy casualty and economic loss. In order to understand how the seismic energy propagates during this earthquake and how it causes the seismic hazard, we simulated the strong ground motions from a representative kinematic source model by Zhang et al. (Chin J Geophys 56(4):1408-1411, 2013) for this earthquake. To include the topographic effects, we used the curved grids finite difference method by Zhang and Chen (Geophys J Int 167(1):337-353, 2006), Zhang et al. (Geophys J Int 190(1):358-378, 2012) to implement the simulations. Our results indicated that the majority of seismic energy concentrated in the epicentral area and the vicinal Sichuan Basin, causing the XI and VII degree intensity. Due to the strong topographic effects of the mountain, the seismic intensity in the border area across the northeastern of Boxing County to the Lushan County also reached IX degree. Moreover, the strong influence of topography caused the amplifications of ground shaking at the mountain ridge, which is easy to cause landslides. These results are quite similar to those observed in the Wenchuan earthquake of 2008 occurred also in a strong topographic mountain area.

Non-climatic factors and long-term, continental-scale changes in seasonally frozen ground

NASA Astrophysics Data System (ADS)

Shiklomanov, Nikolay I.

2012-03-01

Numerous studies indicate that the northern high latitudes are experiencing an unprecedented rate of environmental change, including an increase in air temperatures (e.g. Serreze and Francis 2006), reduction of snow cover (e.g. Brown and Robinson 2011), ecosystem transformations and land cover changes (e.g. Callaghan et al 2011). Many of the potential environmental impacts of global warming in the high latitudes are associated with frozen ground, which occupies about 55% of the unglaciated land area in the northern hemisphere and consists of both permafrost and seasonally frozen ground. Frozen soils have a tremendous impact on hydrologic, climatic and biologic systems. Periodic freezing and thawing promote changes in soil structure, affect the surface and subsurface water cycle, and regulate the availability of nutrients in the soil for plants and biota that depend upon them. Freezing and thawing cycles can affect the decomposition of organic substances in the soil and greenhouse gas exchange between the atmosphere and land surface. Significant efforts have been devoted to permafrost-related studies, including the establishment of standardized observations (e.g. Romanovsky et al 2010, Shiklomanov et al 2008), modeling (e.g. Riseborough et al 2008), and climate-related feedback processes (e.g. Schuur et al 2008). Despite its vast extent and importance, seasonally frozen ground has received much less attention. One of the major obstacles in assessing changes in seasonally frozen ground is the lack of long-term data. In general, observations on soil temperature and freeze propagation are available for a limited area and involve a relatively short time period, precluding assessment of long-term, climate-driven change. A few known exceptions include shallow soil temperature and freeze/thaw depth observations conducted as part of the standard hydrometeorological monitoring system in China (e.g. Zhao et al 2004) and the Soviet Union/Russia (e.g. Gilichinsky et al 2000). In their recent paper entitled 'An observational 71-year history of seasonally frozen ground changes in Eurasian high latitudes', Frauenfeld and Zhang (2011) provided detailed analysis of soil temperature data to assess 1930-2000 trends in seasonal freezing depth. The data were obtained from 387 Soviet non-permafrost meteorological stations. The authors performed systematic, quality-controlled, integrative analysis over the entire former Soviet Union domain. The long-term changes in depth of seasonal freezing were discussed in relation to such forcing variables as air temperature, degree days of freezing/thawing, snow depth and summer precipitation as well as modes of the North Atlantic Oscillation. The spatially average approach adopted for the study provides a generalized continental-scale trend. The study greatly improves, expands and extends previous 1956-90 analysis of the ground thermal regime over the Eurasian high latitudes (Frauenfeld et al 2004). Although the work of Frauenfeld and Zhang (2011) is the most comprehensive assessment of the continental-scale long-term trends in seasonal freezing available to date, more detailed analysis is needed to determine the effect of climate change on seasonally frozen ground. It should be noted that, in addition to the variables considered for analysis, other non-climatic factors affect the depth of freezing propagation. Unlike the surface, which is influenced by the climate directly, the ground even at shallow depth receives a climatic signal that is substantially modified by edaphic processes, contributing to highly localized thermal sensitivities of the ground to climatic forcing. Subsurface properties, soil moisture, and snow and vegetation covers influence the depth of freezing. Topography also plays an important role in establishing the ground thermal regime. It is an important determinant of the amount of heat received by the ground surface, affects the distribution of snow and vegetation, and influences the surface and subsurface moisture regimes. As a result, the ground temperature and the related depth of freezing propagation are characterized by very high variability over short lateral distances. The data used for analysis by Frauenfeld and Zhang are single-point measurements obtained from a network of stations sparsely distributed over a very large spatial domain. Since no variability in edaphic conditions was considered, the presented results should be interpreted with some degree of caution. In addition, long-term soil observations at a single point using unautomated techniques unavoidably cause site disturbance, which may significantly modify the ground thermal regime over time. I would like to emphasize that the generalized continental trend in the depth of seasonal freezing presented by Frauenfeld and Zhang is very likely associated with changes in atmospheric forcing. However, any long-term continental trends of such a spatially heterogeneous and sensitive parameter as shallow soil temperature potentially include a significant non-climatic component. Although the single-point temperature data used by Frauenfeld and Zhang might not be sufficient to fully evaluate the localized effects on the overall trend, they are a terrific asset for further studies on climate and ground thermal regime. Detailed spatial assessment of the available ground temperature records over relatively homogeneous regions is a necessary next step in the assessment of climate-induced changes in seasonally frozen ground. Such an analysis is likely to show significant regional differences in long-term freeze propagation trends over Northern Eurasia and reveal region-specific sensitivities of the ground thermal regime to climatic forcing. References Brown R D and Robinson D A 2011 Northern hemisphere spring snow cover variability and change over 1922-2010 including an assessment of uncertainty Cryosphere 5 219-29 Callaghan T V, Tweedie C E and Webber P J 2011 Multi-decadal changes in tundra environments and ecosystems: the International Polar Year-Back to the Future Project (IPYBTF) AMBIO 40 555-7 Frauenfeld O W and Zhang T 2011 An observational 71-year history of seasonally frozen ground changes in the Eurasian high latitudes Environ. Res. Lett. 6 044024 Frauenfeld O W, Zhang T, Barry R G and Gilichinsky D 2004 Interdecadal changes in seasonal freeze and thaw depths in Russia J. Geophys. Res. 109 D5101 Gilichinsky D A et al 2000 Use of the data of hydrometeorological survey for century history of soil temperature trends in the seasonally frozen and permafrost areas of Russia Earth Cryosp. 4 59-66 (in Russian) Riseborough D, Shiklomanov N I, Etselmuller B and Gruber S 2008 Recent advances in permafrost modeling Permafr. Pereglac. Process. 19 137-56 Romanovsky V E et al 2010 Thermal state of permafrost in Russia Permafr. Periglac. Process. 21 136-55 Schuur E A G et al 2008 Vulnerability of permafrost carbon to climate change: implications for the global carbon cycle Bioscience 58 701-14 Serreze M C and Francis J A 2006 The Arctic amplification debate Clim. Change 76 241-64 Shiklomanov N I, Nelson F E, Streletskiy D A, Hinkel K M and Brown J 2008 The circumpolar active layer monitoring (CALM) program: data collection, management, and dissemination strategies Proc. of the 9th International Conf. on Permafrost (Fairbanks, AK, 29 June-3 July 2008) vol 1, pp 1647-52 Zhao L, Ping C L, Yang D, Cheng G, Ding Y and Liu S 2004 Changes of climate and seasonally frozen ground over the past 30 years in Qinghai-Xizang (Tibetan) Plateau, China Glob. Planet. Change 43 19-31

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fontes, Christopher J.; Zhang, Hong Lin

We calculated relativistic distorted-wave collision strength for all possible Δn=0 transitions, where n denotes the valence shell of the ground level, in the 67 Li-like, F-like and Na-like ions with Z in the range 26 ≤ Z ≤92. This choice produces 3 transitions with n=2 in the Li-like and F-like ions, and 10 transitions with n=3 in the Na-like ions. Moreover, for the Li-like and F-like ions, the calculations were made for the six final, or scattered, electron energies E'=0.008,0.04,0.10,0.21,0.41, and 0.75, where E' is in units of Zmore » $$2\\atop{eff}$$ Ry with Z eff = Z- 1.66 for Li-like ions and Z eff= Z- 6.667 for F-like ions. For the Na-like ions, the calculations were made for the six final electron energies E'=0.0025,0.015,0.04,0.10,0.21, and 0.40, with Z eff = Z- 8.34. In the present calculations, an improved “top-up” method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb–Bethe approximation used in previous works by Zhang, Sampson and Fontes [H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 31; H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 48 (1991) 25; D.H. Sampson, H.L. Zhang, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 209]. In those previous works, collision strengths were also provided for Li-, F- and Na-like ions, but for a more comprehensive set of transitions. Finally, the collision strengths covered in the present work should be more accurate than the corresponding data given in those previous works and are presented here to replace those earlier results.« less

Demonstrating Improvements from a NWP-based Satellite Precipitation Adjustment Technique in Tropical Mountainous Regions

NASA Astrophysics Data System (ADS)

Zhang, X.; Anagnostou, E. N.

2016-12-01

This research contributes to the improvement of high resolution satellite applications in tropical regions with mountainous topography. Such mountainous regions are usually covered by sparse networks of in-situ observations while quantitative precipitation estimation from satellite sensors exhibits strong underestimation of heavy orographically enhanced storm events. To address this issue, our research applies a satellite error correction technique based solely on high-resolution numerical weather predictions (NWP). Our previous work has demonstrated the accuracy of this method in two mid-latitude mountainous regions (Zhang et al. 2013*1, Zhang et al. 2016*2), while the current research focuses on a comprehensive evaluation in three topical mountainous regions: Colombia, Peru and Taiwan. In addition, two different satellite precipitation products, NOAA Climate Prediction Center morphing technique (CMORPH) and Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks-Cloud Classification System (PERSIANN-CCS), are considered. The study includes a large number of heavy precipitation events (68 events over the three regions) in the period 2004 to 2012. The NWP-based adjustments of the two satellite products are contrasted to their corresponding gauge-adjusted post-processing products. Preliminary results show that the NWP-based adjusted CMORPH product is consistently improved relative to both original and gauge-adjusted precipitation products for all regions and storms examined. The improvement of PERSIANN-CCS product is less significant and less consistent relative to the CMORPH performance improvements from the NWP-based adjustment. *1Zhang, Xinxuan, Emmanouil N. Anagnostou, Maria Frediani, Stavros Solomos, and George Kallos. "Using NWP simulations in satellite rainfall estimation of heavy precipitation events over mountainous areas." Journal of Hydrometeorology 14, no. 6 (2013): 1844-1858.*2 Zhang, Xinxuan, Emmanouil N. Anagnostou, and Humberto Vergara. "Hydrologic Evaluation of NWP-Adjusted CMORPH Estimates of Hurricane-Induced Precipitation in the Southern Appalachians." Journal of Hydrometeorology 17.4 (2016): 1087-1099.

On the relation between dependency distance, crossing dependencies, and parsing. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Gómez-Rodríguez, Carlos

2017-07-01

Liu et al. [1] provide a comprehensive account of research on dependency distance in human languages. While the article is a very rich and useful report on this complex subject, here I will expand on a few specific issues where research in computational linguistics (specifically natural language processing) can inform DDM research, and vice versa. These aspects have not been explored much in [1] or elsewhere, probably due to the little overlap between both research communities, but they may provide interesting insights for improving our understanding of the evolution of human languages, the mechanisms by which the brain processes and understands language, and the construction of effective computer systems to achieve this goal.

Comparison of internal wave properties calculated by Boussinesq equations with/without rigid-lid assumption

NASA Astrophysics Data System (ADS)

Liu, C. M.

2017-12-01

Wave properties predicted by the rigid-lid and the free-surface Boussinesq equations for a two-fluid system are theoretically calculated and compared in this study. Boussinesq model is generally applied to numerically simulate surface waves in coastal regions to provide credible information for disaster prevention and breaker design. As for internal waves, Liu et al. (2008) and Liu (2016) respectively derived a free-surface model and a rigid-lid Boussinesq models for a two-fluid system. The former and the latter models respectively contain four and three key variables which may result in different results and efficiency while simulating. Therefore, present study shows the results theoretically measured by these two models to provide more detailed observation and useful information for motions of internal waves.

Reviews of environmental contamination and toxicology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ware, G.

2007-07-01

Review of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavour in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications. This edition contains a paper 'Health effects of arsenic, fluorine and selenium from indoor burning of Chinese coal, by Liu Guijian, Zheng Liugen, Nurdan S. Duzgoren-Aydin, Gao Lianfen, Liu Junhua, and Peng Zicheng. Other papers are: Chemistry and fate of simazine; Ethanol production: energy, economic, and environmental losses; Arsenic behaviour from groundwater and soil to crops: impacts on agriculturemore » and food safety; Mercury content of hair in different populations relative to fish consumption; and Toxicology of 1,3-butadiene, chloroprene, and isoprene. 15 ills.« less

Extending network approach to language dynamics and human cognition. Comment on "Approaching human language with complex networks" by Cong and Liu

NASA Astrophysics Data System (ADS)

Gong, Tao; Shuai, Lan; Wu, Yicheng

2014-12-01

By analyzing complex networks constructed from authentic language data, Cong and Liu [1] advance linguistics research into the big data era. The network approach has revealed many intrinsic generalities and crucial differences at both the macro and micro scales between human languages. The axiom behind this research is that language is a complex adaptive system [2]. Although many lexical, semantic, or syntactic features have been discovered by means of analyzing the static and dynamic linguistic networks of world languages, available network-based language studies have not explicitly addressed the evolutionary dynamics of language systems and the correlations between language and human cognition. This commentary aims to provide some insights on how to use the network approach to study these issues.

Ionospheric Anomalies of the 2011 Tohoku Earthquake with Multiple Observations during Magnetic Storm Phase

NASA Astrophysics Data System (ADS)

Liu, Yang

2017-04-01

Ionospheric anomalies linked with devastating earthquakes have been widely investigated by scientists. It was confirmed that GNSS TECs suffered from drastically increase or decrease in some diurnal periods prior to the earthquakes. Liu et al (2008) applied a TECs anomaly calculation method to analyze M>=5.9 earthquakes in Indonesia and found TECs decadence within 2-7 days prior to the earthquakes. Nevertheless, strong TECs enhancement was observed before M8.0 Wenchuan earthquake (Zhao et al 2008). Moreover, the ionospheric plasma critical frequency (foF2) has been found diminished before big earthquakes (Pulinets et al 1998; Liu et al 2006). But little has been done regarding ionospheric irregularities and its association with earthquake. Still it is difficult to understand real mechanism between ionospheric anomalies activities and its precursor for the huge earthquakes. The M9.0 Tohoku earthquake, happened on 11 March 2011, at 05:46 UT time, was recognized as one of the most dominant events in related research field (Liu et al 2011). A median geomagnetic disturbance also occurred accompanied with the earthquake, which makes the ionospheric anomalies activities more sophisticated to study. Seismic-ionospheric disturbance was observed due to the drastic activities of earth. To further address the phenomenon, this paper investigates different categories of ionospheric anomalies induced by seismology activity, with multiple data sources. Several GNSS ground data were chosen along epicenter from IGS stations, to discuss the spatial-temporal correlations of ionospheric TECs in regard to the distance of epicenter. We also apply GIM TEC maps due to its global coverage to find diurnal differences of ionospheric anomalies compared with geomagnetic quiet day in the same month. The results in accordance with Liu's conclusions that TECs depletion occurred at days quite near the earthquake day, however the variation of TECs has special regulation contrast to the normal quiet days. Associated with geomagnetic storm at similar time, radio occultation data provided by COSMIC were deeply investigated within the whole month. It's quite different that the storm or earthquake didn't trigger scintillation burst. This is probably due to the storm occurrence local time was in noon sector, which has little impact on ionospheric irregularities increase, but help to enhance the effect of westward electricity, which on the other hand diminishes scintillation bubbles (Li et al 2008). A small geomagnetic disturbance was also found almost a week prior to the earthquake, the relationship of this event to the major earthquake is worth further discussion. Similar analysis of GNSS TECs have been done, the results indicated that it can be also referred as precursor to the major earthquake. Li G, Ning B, Zhao B, et al. Effects of geomagnetic storm on GPS ionospheric scintillations at Sanya[J]. Journal of Atmospheric and Solar-Terrestrial Physics, 2008, 70(7):1034-1045. Liu J Y, Chen Y I, Chuo Y J, et al. A statistical investigation of pre-earthquake ionospheric anomaly[J]. Journal of Geophysical Research Atmospheres, 2006, 111(A5). Liu J Y, Sun Y Y. Seismo-traveling ionospheric disturbances of ionograms observed during the 2011 Mw 9.0 Tohoku Earthquake[J]. Earth, Planets and Space, 2011, 63(7):897-902. Zhao B, Wang M, Yu T, et al. Is an unusual large enhancement of ionospheric electron density linked with the 2008 great Wenchuan earthquake?[J]. Journal of Geophysical Research Atmospheres, 2008, 113(A11):A11304. Pulinets S A. Seismic activity as a source of the ionospheric variability [J]. Advances in Space Research, 1998, 22(6):903-906.

CHROMASSI: a therapy advice system based on chrono-massage and acupression using the method of ZiWuLiuZhu.

PubMed

Nguyen, H P; Le, D L; Tran, Q M; Nguyen, V T; Nguyen, N O

1995-01-01

Massage and Acupression have a history of many years of use by the Vietnamese people in the treatment of diseases, and they can give wonderful therapeutic effects in painful syndromes and chronic diseases, etc. On the other hand, some methods of Chrono-Acupuncture based on chronobiological theory and the holistic concept of traditional medicine are studied and applied in clinical applications. This paper presents the therapy advice system based on Chrono-Massage and Acupression using the method of ZiWuLiuZhu called CHROMASSI. The system includes four major parts. Massage and Acupression Teaching: This part can provide the user with some background in Massage and Acupression theory such as the pathology of the meridians, the classification of points and their function, the therapeutic properties of points, the methods of Massage and Acupression (including Pression, Friction, Rubbing, Light Massage, Petrissage, Rolling and Rubbing, Percussion and Vibration), and the direction of the meridians circulation, displaying AcuPoints represented by color pictures of the 12 main meridians and 2 vessels. More than 330 popular AcuPoints are used in the system. Open AcuPoint Calculating: This module can help us to calculate open AcuPoints based on data about days, months, years and hours using the special method of ZiWuLiuZhu. The Points adopted by ZiWuLiuZhu are the Five Shu Points and Source Points including 66 points (all of them are located below the elbows and knees). The effectiveness of these points becomes particularly evident when they are needled or punctured at optimum time intervals. For example, at 9:00 a.m., September 22, 1994, the open Points by the ZiWuLiuZhu method will be the points K2 (Nhien Coc) and K10 (Am Coc). According to the chronotherapeutic method, first we have to pressure (or puncture) the above points in order to attain the sensation RDac KhiS (arrival of energy), then pressure the other treating points as in ordinary Massage and Acupression. Therapy Consultation: Knowledge of the system was provided by Prof. Nguyen Van Thang and Doctor Nguyen Nhu Oanh at the Vietnam National Institute of Oriental Medicine. CHROMASSI is able to advise on ways to treat about 153 diseases and symptoms in the following fields: Aches and Pains, Insomnia, Common Cold and Influenza, Sexual Disturbances, Medical Aesthetics in Face, Breast and Buttock, Hygiene, Cardio-Vascular Tract, Digestive Tract, Urinary Tract, Respiratory Tract, Genital Tract, Ear-Nose-Throat Tract, Nervous Tract. The system can provide information about Remarks, Acupoints formulas for treating by Massage and Acupression with colour pictures of meridians. Explanation: The CHROMASSI system can explain why the AcuPoints are used for treating diseases based on the theoretical bases of traditional Vietnamese medicine and on the meridians and collaterals system theory. The colour pictures representing the circulation of vital energy in the meridians are used for explanation. The CHROMASSI system was developed in TURBO-PROLOG and TURBO-PASCAL and can run on IBM PC/AT computers and compatibles. The system can be used for teaching and for clinics of Massage and Acupression combined with Chronotherapeutics. At present the system is used by some physicians for clinical applications. The first results indicate that, in 20 cases of generalized headache compared with the control group, the combining of chronoacupression using the ZiWuLiuZhu method and ordinary Massage and Acupression gave better effects than that obtained by either method alone.

Altered Sleep Stage Transitions of REM Sleep: A Novel and Stable Biomarker of Narcolepsy

PubMed Central

Liu, Yaping; Zhang, Jihui; Lam, Venny; Ho, Crover Kwok Wah; Zhou, Junying; Li, Shirley Xin; Lam, Siu Ping; Yu, Mandy Wai Man; Tang, Xiangdong; Wing, Yun-Kwok

2015-01-01

Objectives: To determine the diagnostic values, longitudinal stability, and HLA association of the sleep stage transitions in narcolepsy. Methods: To compare the baseline differences in the sleep stage transition to REM sleep among 35 patients with type 1 narcolepsy, 39 patients with type 2 narcolepsy, 26 unaffected relatives, and 159 non-narcoleptic sleep patient controls, followed by a reassessment at a mean duration of 37.4 months. Results: The highest prevalence of altered transition from stage non-N2/N3 to stage R in multiple sleep latency test (MSLT) and nocturnal polysomnography (NPSG) was found in patients with type 1 narcolepsy (92.0% and 57.1%), followed by patients with type 2 narcolepsy (69.4% and 12.8%), unaffected relatives (46.2% and 0%), and controls (39.3% and 1.3%). Individual sleep variables had varied sensitivity and specificity in diagnosing narcolepsy. By incorporating a combination of sleep variables, the decision tree analysis improved the sensitivity to 94.3% and 82.1% and enhanced specificity to 82.4% and 83% for the diagnosis of type 1 and type 2 narcolepsy, respectively. There was a significant association of DBQ1*0602 with the altered sleep stage transition (OR = 16.0, 95% CI: 1.7–149.8, p = 0.015). The persistence of the altered sleep stage transition in both MSLT and NPSG was high for both type 1 (90.5% and 64.7%) and type 2 narcolepsy (92.3% and 100%), respectively. Conclusions: Altered sleep stage transition is a significant and stable marker of narcolepsy, which suggests a vulnerable wake-sleep dysregulation trait in narcolepsy. Altered sleep stage transition has a significant diagnostic value in the differential diagnosis of hypersomnias, especially when combined with other diagnostic sleep variables in decision tree analysis. Citation: Liu Y, Zhang J, Lam V, Ho CK, Zhou J, Li SX, Lam SP, Yu MW, Tang X, Wing YK. Altered sleep stage transitions of REM sleep: a novel and stable biomarker of narcolepsy. J Clin Sleep Med 2015;11(8):885–894. PMID:25979093

Traditional Chinese Medicine Induced Liver Injury

PubMed Central

2014-01-01

Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol Zhee, Cang Er Zi, Chai Hu, Chaso, Chi R Yun, Chuan Lian Zi, Ci Wu Jia, Da Chai Hu Tang, Da Huang, Du Huo, Gan Cao, Ge Gen, Ho Shou Wu, Hu Bohe You, Hu Zhang, Huang Qin, Huang Yao Zi, Hwang Geun Cho, Ji Gu Cao, Ji Ji, Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou Wu Pian, Tian Hua Fen, White flood, Wu Bei Zi, Xi Shu, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, Zhen Chu Cao, and various unclassified Chinese herbal mixtures. Causality was firmly established for a number of herbal TCM products by a positive reexposure test result, the liver specific scale of CIOMS (Council for International Organizations of Medical Sciences), or both. Otherwise, the quality of case data was mixed, especially regarding analysis of the herb ingredients because of adulteration with synthetic drugs, contamination with heavy metals, and misidentification. In addition, non-herbal TCM elements derived from Agaricus blazei, Agkistrodon, Antelope, Bombyx, Carp, Fish gallbladder, Phellinus, Scolopendra, Scorpio, and Zaocys are also known or potential hepatotoxins. For some patients, the clinical course was severe, with risks for acute liver failure, liver transplantation requirement, and lethality. In conclusion, the use of few herbal TCM products may rarely be associated with hepatotoxicity in some susceptible individuals, necessitating a stringent pretreatment evaluation of the risk/benefit ratio, based on results of multicenter, randomized, double-blind, placebo-controlled clinical trials. PMID:26357619

Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density.

PubMed

Wang, W; Huang, S; Hou, W; Liu, Y; Fan, Q; He, A; Wen, Y; Hao, J; Guo, X; Zhang, F

2017-10-01

Several genome-wide association studies (GWAS) of bone mineral density (BMD) have successfully identified multiple susceptibility genes, yet isolated susceptibility genes are often difficult to interpret biologically. The aim of this study was to unravel the genetic background of BMD at pathway level, by integrating BMD GWAS data with genome-wide expression quantitative trait loci (eQTLs) and methylation quantitative trait loci (meQTLs) data METHOD: We employed the GWAS datasets of BMD from the Genetic Factors for Osteoporosis Consortium (GEFOS), analysing patients' BMD. The areas studied included 32 735 femoral necks, 28 498 lumbar spines, and 8143 forearms. Genome-wide eQTLs (containing 923 021 eQTLs) and meQTLs (containing 683 152 unique methylation sites with local meQTLs) data sets were collected from recently published studies. Gene scores were first calculated by summary data-based Mendelian randomisation (SMR) software and meQTL-aligned GWAS results. Gene set enrichment analysis (GSEA) was then applied to identify BMD-associated gene sets with a predefined significance level of 0.05. We identified multiple gene sets associated with BMD in one or more regions, including relevant known biological gene sets such as the Reactome Circadian Clock (GSEA p-value = 1.0 × 10 -4 for LS and 2.7 × 10 -2 for femoral necks BMD in eQTLs-based GSEA) and insulin-like growth factor receptor binding (GSEA p-value = 5.0 × 10 -4 for femoral necks and 2.6 × 10 -2 for lumbar spines BMD in meQTLs-based GSEA). Our results provided novel clues for subsequent functional analysis of bone metabolism, and illustrated the benefit of integrating eQTLs and meQTLs data into pathway association analysis for genetic studies of complex human diseases. Cite this article : W. Wang, S. Huang, W. Hou, Y. Liu, Q. Fan, A. He, Y. Wen, J. Hao, X. Guo, F. Zhang. Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density. Bone Joint Res 2017;6:572-576. © 2017 Wang et al.

Haemophilus ducreyi Seeks Alternative Carbon Sources and Adapts to Nutrient Stress and Anaerobiosis during Experimental Infection of Human Volunteers.

PubMed

Gangaiah, Dharanesh; Zhang, Xinjun; Baker, Beth; Fortney, Kate R; Gao, Hongyu; Holley, Concerta L; Munson, Robert S; Liu, Yunlong; Spinola, Stanley M

2016-05-01

Haemophilus ducreyi causes the sexually transmitted disease chancroid in adults and cutaneous ulcers in children. In humans, H. ducreyi resides in an abscess and must adapt to a variety of stresses. Previous studies (D. Gangaiah, M. Labandeira-Rey, X. Zhang, K. R. Fortney, S. Ellinger, B. Zwickl, B. Baker, Y. Liu, D. M. Janowicz, B. P. Katz, C. A. Brautigam, R. S. Munson, Jr., E. J. Hansen, and S. M. Spinola, mBio 5:e01081-13, 2014, http://dx.doi.org/10.1128/mBio.01081-13) suggested that H. ducreyi encounters growth conditions in human lesions resembling those found in stationary phase. However, how H. ducreyi transcriptionally responds to stress during human infection is unknown. Here, we determined the H. ducreyi transcriptome in biopsy specimens of human lesions and compared it to the transcriptomes of bacteria grown to mid-log, transition, and stationary phases. Multidimensional scaling showed that the in vivo transcriptome is distinct from those of in vitro growth. Compared to the inoculum (mid-log-phase bacteria), H. ducreyi harvested from pustules differentially expressed ∼93 genes, of which 62 were upregulated. The upregulated genes encode homologs of proteins involved in nutrient transport, alternative carbon pathways (l-ascorbate utilization and metabolism), growth arrest response, heat shock response, DNA recombination, and anaerobiosis. H. ducreyi upregulated few genes (hgbA, flp-tad, and lspB-lspA2) encoding virulence determinants required for human infection. Most genes regulated by CpxRA, RpoE, Hfq, (p)ppGpp, and DksA, which control the expression of virulence determinants and adaptation to a variety of stresses, were not differentially expressed in vivo, suggesting that these systems are cycling on and off during infection. Taken together, these data suggest that the in vivo transcriptome is distinct from those of in vitro growth and that adaptation to nutrient stress and anaerobiosis is crucial for H. ducreyi survival in humans. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Spin-Orbit Torque-Assisted Switching in Magnetic Insulator Thin Films with Perpendicular Magnetic Anisotropy

NASA Astrophysics Data System (ADS)

Wu, Mingzhong

As an in-plane charge current flows in a heavy metal film with spin-orbit coupling, it produces a torque that can induce magnetization switching in a neighboring ferromagnetic metal film. Such spin-orbit torque (SOT)-induced switching has been studied extensively in recent years and has shown higher efficiency than switching using conventional spin-transfer torque. This presentation reports the SOT-assisted switching in heavy metal/magnetic insulator systems.1 The experiments made use of Pt/BaFe12O19 bi-layered structures. Thanks to its strong spin-orbit coupling, Pt has been widely used to produce pure spin currents in previous studies. BaFe12O19 is an M-type barium hexagonal ferrite and is often referred as BaM. It is one of the few magnetic insulators with strong magneto-crystalline anisotropy and shows an effective uniaxial anisotropy field of about 17 kOe. It's found that the switching response in the BaM film strongly depends on the charge current applied to the Pt film. When a constant magnetic field is applied in the film plane, the charge current in the Pt film can switch the normal component of the magnetization (M⊥) in the BaM film between the up and down states. The current also dictates the up and down states of the remnant magnetization when the in-plane field is reduced to zero. When M⊥ is measured by sweeping an in-plane field, the response manifests itself as a hysteresis loop, which evolves in a completely opposite manner if the sign of the charge current is flipped. When the coercivity is measured by sweeping an out-of-plane field, its value can be reduced or increased by as much as about 500 Oe if an appropriate charge current is applied. 1. P. Li, T. Liu, H. Chang, A. Kalitsov, W. Zhang, G. Csaba, W. Li, D. Richardson, A. Demann, G. Rimal, H. Dey, J. S. Jiang, W. Porod, S. Field, J. Tang, M. C. Marconi, A. Hoffmann, O. Mryasov, and M. Wu, Nature Commun. 7:12688 doi: 10.1038/ncomms12688 (2016).

Emergence of Sex Differences in Insomnia Symptoms in Adolescents: A Large-Scale School-Based Study

PubMed Central

Zhang, Jihui; Chan, Ngan Yin; Lam, Siu Ping; Li, Shirley Xin; Liu, Yaping; Chan, Joey W.Y.; Kong, Alice Pik Shan; Ma, Ronald C.W.; Chan, Kate C.C.; Li, Albert Martin; Wing, Yun-Kwok

2016-01-01

Study Objectives: This study aimed to explore the moderation of pubertal status on the onset of sex differences in the prevalence of insomnia symptoms and their health correlates. Methods: A total of 7,507 children and adolescents (weighted percentage of female: 48.5%) aged between 6–17 y were recruited from thirty-one primary and secondary schools. Participants with difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS), and/or early morning awakening (EMA) ≥ 3 times/week in the past month were considered as having insomnia symptoms. The severity of insomnia was measured by the Insomnia Severity Index (ISI). Results: The prevalence of insomnia symptoms increased from 3.4% to 12.2% in girls (3.6-fold) and from 4.3% to 9.1% in boys (2.1-fold) from Tanner stage 1 to 5. There was a significant interaction between sex and Tanner stage in the prevalence of insomnia (P < 0.001) with an emergence of female preponderance at Tanner stage 4 even after controlling for age, family income, and school start time. Similar sex-Tanner stage interactions were found in DIS, DMS, and ISI total score but not EMA. Insomnia symptoms were strongly associated with behavioral problems, poor mental health, and poor general health in both sexes. Boys with insomnia would report more maladaptive lifestyles (smoking, alcohol, and energy drinks) whereas girls with insomnia were more susceptible to emotional and relationship difficulties. Conclusions: Pubertal maturation was associated with a progressive increase in the prevalence of insomnia symptoms with the emergence of female preponderance in both the prevalence and severity of insomnia symptoms at late puberty. Clinical Trials Registration: Chinese Clinical Trial Register, http://www.chictr.org.cn, ID: ChiCTR-TRC-12002798 Citation: Zhang J, Chan NY, Lam SP, Li SX, Liu Y, Chan JW, Kong AP, Ma RC, Chan KC, Li AM, Wing YK. Emergence of sex differences in insomnia symptoms in adolescents: a large-scale school-based study. SLEEP 2016;39(8):1563–1570. PMID:27091537

Mortality and Its Risk Factors in Patients with Rapid Eye Movement Sleep Behavior Disorder

PubMed Central

Zhou, Junying; Zhang, Jihui; Lam, Siu Ping; Mok, Vincent; Chan, Anne; Li, Shirley Xin; Liu, Yaping; Tang, Xiangdong; Yung, Wing Ho; Wing, Yun Kwok

2016-01-01

Study Objectives: To determine the mortality and its risk factors in patients with rapid eye movement (REM) sleep behavior disorder (RBD). Methods: A total of 205 consecutive patients with video-polysomnography confirmed RBD (mean age = 66.4 ± 10.0 y, 78.5% males) were recruited. Medical records and death status were systematically reviewed in the computerized records of the health care system. Standardized mortality ratio (SMR) was used to calculate the risk ratio of mortality in RBD with reference to the general population. Results: Forty-three patients (21.0%) died over a mean follow-up period of 7.1 ± 4.5 y. The SMR was not increased in the overall sample, SMR (95% confidence interval [CI]) = 1.00 (0.73–1.33). However, SMR (95% CI) increased to 1.80 (1.21–2.58) and 1.75 (1.11–2.63) for RBD patients in whom neurodegenerative diseases and dementia, respectively, eventually developed. In the Cox regression model, mortality risk was significantly associated with age (hazard ratio [HR] = 1.05; 95% CI, 1.01–1.10), living alone (HR = 2.04; 95% CI, 1.39–2.99), chronic obstructive pulmonary disease (HR = 3.38; 95% CI, 1.21–9.46), cancer (HR = 10.09; 95% CI, 2.65–38.42), periodic limb movements during sleep (HR = 3.06; 95% CI, 1.50–6.24), and development of neurodegenerative diseases (HR = 2.84; 95% CI, 1.47–5.45) and dementia (HR = 2.66; 95% CI, 1.39–5.08). Conclusions: Patients with RBD have a higher mortality rate than the general population only if neurodegenerative diseases develop. Several risk factors on clinical and sleep aspects are associated with mortality in RBD patients. Our findings underscore the necessity of timely neuroprotective interventions in the early phase of RBD before the development of neurodegenerative diseases. Citation: Zhou J, Zhang J, Lam SP, Mok V, Chan A, Li SX, Liu Y, Tang X, Yung WH, Wing YK. Mortality and its risk factors in patients with rapid eye movement sleep behavior disorder. SLEEP 2016;39(8):1543–1550. PMID:27306273

Estimation of the weighted CTDI{sub {infinity}} for multislice CT examinations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li Xinhua; Zhang Da; Liu, Bob

2012-02-15

Purpose: The aim of this study was to examine the variations of CT dose index (CTDI) efficiencies, {epsilon}(CTDI{sub 100})=CTDI{sub 100}/CTDI{sub {infinity}}, with bowtie filters and CT scanner types. Methods: This was an extension of our previous study [Li, Zhang, and Liu, Phys. Med. Biol. 56, 5789-5803 (2011)]. A validated Monte Carlo program was used to calculate {epsilon}(CTDI{sub 100}) on a Siemens Somatom Definition scanner. The {epsilon}(CTDI{sub 100}) dependencies on tube voltages and beam widths were tested in previous studies. The influences of different bowtie filters and CT scanner types were examined in this work. The authors tested the variations ofmore » {epsilon}(CTDI{sub 100}) with bowtie filters on the Siemens Definition scanner. The authors also analyzed the published CTDI measurements of four independent studies on five scanners of four models from three manufacturers. Results: On the Siemens Definition scanner, the difference in {epsilon}(CTDI{sub W}) between using the head and body bowtie filters was 2.5% (maximum) in the CT scans of the 32-cm phantom, and 1.7% (maximum) in the CT scans of the 16-cm phantom. Compared with CTDI{sub W}, the weighted CTDI{sub {infinity}} increased by 30.5% (on average) in the 32-cm phantom, and by 20.0% (on average) in the 16-cm phantom. These results were approximately the same for 80-140 kV and 1-40 mm beam widths (4.2% maximum deviation). The differences in {epsilon}(CTDI{sub 100}) between the simulations and the direct measurements of four previous studies were 1.3%-5.0% at the center/periphery of the 16-cm/32-cm phantom (on average). Conclusions: Compared with CTDI{sub vol}, the equilibrium dose for large scan lengths is 30.5% higher in the 32-cm phantom, and is 20.0% higher in the 16-cm phantom. The relative increases are practically independent of tube voltages (80-140 kV), beam widths (up to 4 cm), and the CT scanners covered in this study.« less

Role of Arcuate Nucleus in the Regulation of Feeding Behavior in the Process of Altitude Acclimatization in Rats.

PubMed

Liu, Xiang-Wen; Yin, Jie; Ma, Qi-Sheng; Qi, Chu-Chu; Mu, Ji-Ying; Zhang, Lang; Gao, Li-Ping; Jing, Yu-Hong

2017-09-01

Liu, Xiang-Wen, Jie Yin, Qi-Sheng Ma, Chu-Chu Qi, Ji-Ying Mu, Lang Zhang, Li-Ping Gao, and Yu-Hong Jing. Role of arcuate nucleus in the regulation of feeding behavior in the process of altitude acclimatization in rats. High Alt Med Biol. 18:234-241, 2017.-Highly efficient energy utilization and metabolic homeostasis maintenance rely on neuromodulation. Altitude exposure is known to stimulate neuroendocrine systems to respond to acute hypoxia and adaptive acclimatization. However, limited data on how the adaptive regulation of the arcuate nucleus performs in the process of altitude acclimatization are available. In the present study, male Sprague Dawley rats were transported to Huashixia, Qinghai (with an altitude of 4400 m) from Xian (with an altitude of 300 m) by air; rats were consistently raised in Xian as control. Food uptake and body weight were measured consecutively after being subjected to high-altitude condition. Contents of plasma leptin and ghrelin were analyzed by the Enzyme Linked Immunosorbent Assay (ELISA) Kits. Brain coronal sections were obtained, and neuropeptide Y (NPY), proopiomelanocotin (POMC), and c-fos immunoreactivity in arcuate nucleus were observed. Arcuate nucleus was isolated from the hypothalamus, and the mRNA of NPY and POMC were measured by quantitative real-time polymerase chain reaction. Our results showed both food consumption and body weight decreased in the high plateau compared with rats raised in the low-altitude condition. Plasma leptin increased at the early stage, and ghrelin decreased at a later stage after reaching the high plateau. The peak of c-fos immunoreactivity in the arcuate nucleus was at day 3 after reaching the high plateau. The expression level of NPY increased, and POMC decreased in the arcuate nucleus at day 7 after reaching the high plateau compared with the plain control group. These results indicate that the arcuate nucleus of hypothalamus performs an important function in regulating feeding behavior during altitude acclimatization. Our study suggested that altitude acclimation is regulated by the hypothalamus that received leptin and ghrelin signals to response by its microcircuit, including NPY- and POMC-neurons in the arcuate nucleus.

From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus.

PubMed

Dooley, Andrea J; Shindo, Nice; Taggart, Barbara; Park, Jewn-Giew; Pang, Yuan-Ping

2006-02-15

Virtual screening, a fast, computational approach to identify drug leads [Perola, E.; Xu, K.; Kollmeyer, T. M.; Kaufmann, S. H.; Prendergast, F. G. J. Med. Chem.2000, 43, 401; Miller, M. A. Nat. Rev. Drug Disc.2002, 1 220], is limited by a known challenge in crystallographically determining flexible regions of proteins. This approach has not been able to identify active inhibitors of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) using solely the crystal structures of a SARS-CoV cysteine proteinase with a flexible loop in the active site [Yang, H. T.; Yang, M. J.; Ding, Y.; Liu, Y. W.; Lou, Z. Y. Proc. Natl. Acad. Sci. U.S.A.2003, 100, 13190; Jenwitheesuk, E.; Samudrala, R. Bioorg. Med. Chem. Lett.2003, 13, 3989; Rajnarayanan, R. V.; Dakshanamurthy, S.; Pattabiraman, N. Biochem. Biophys. Res. Commun.2004, 321, 370; Du, Q.; Wang, S.; Wei, D.; Sirois, S.; Chou, K. Anal. Biochem.2005, 337, 262; Du, Q.; Wang, S.; Zhu, Y.; Wei, D.; Guo, H. Peptides2004, 25, 1857; Lee, V.; Wittayanarakul, K.; Remsungenen, T.; Parasuk, V.; Sompornpisut, P. Science (Asia)2003, 29, 181; Toney, J.; Navas-Martin, S.; Weiss, S.; Koeller, A. J. Med. Chem.2004, 47, 1079; Zhang, X. W.; Yap, Y. L. Bioorg. Med. Chem.2004, 12, 2517]. This article demonstrates a genome-to-drug-lead approach that uses terascale computing to model flexible regions of proteins, thus permitting the utilization of genetic information to identify drug leads expeditiously. A small-molecule inhibitor of SARS-CoV, exhibiting an effective concentration (EC50) of 23 microM in cell-based assays, was identified through virtual screening against a computer-predicted model of the cysteine proteinase. Screening against two crystal structures of the same proteinase failed to identify the 23-microM inhibitor. This study suggests that terascale computing can complement crystallography, broaden the scope of virtual screening, and accelerate the development of therapeutics to treat emerging infectious diseases such as SARS and Bird Flu.

Inverse U-shaped Association between Sleep Duration and Semen Quality: Longitudinal Observational Study (MARHCS) in Chongqing, China

PubMed Central

Chen, Qing; Yang, Huan; Zhou, Niya; Sun, Lei; Bao, Huaqiong; Tan, Lu; Chen, Hongqiang; Ling, Xi; Zhang, Guowei; Huang, Linping; Li, Lianbing; Ma, Mingfu; Yang, Hao; Wang, Xiaogang; Zou, Peng; Peng, Kaige; Liu, Taixiu; Cui, Zhihong; Ao, Lin; Roenneberg, Till; Zhou, Ziyuan; Cao, Jia

2016-01-01

Study Objectives: To investigate the association between sleep duration and semen parameters as well as reproductive hormone levels. Methods: We designed a cohort of male college students in Chongqing, China. A total of 796 subjects were recruited in 2013 and 656 (82.4%) were followed up in 2014. Each time, semen and peripheral blood samples were collected for semen quality and reproductive hormone measurement. Sleep duration was estimated by revised Munich Chronotype Questionnaire. In 2014, sleep quality was also measured by Pittsburgh Sleep Quality Index (PSQI). Results: There was a substantial inverse U-shaped association between sleep duration and two semen parameters (semen volume and total sperm number), with 7.0–7.5 h/day of sleep showing highest parameters. Either longer or shorter sleep was associated with decreased semen parameters in a dose-response manner (P = 0.002 and 0.001, respectively). Sleeping > 9.0 h was associated with a 21.5% (95% confidence interval 9.2, 32.2) reduction in semen volume and 39.4% (23.3, 52.1) reduction in total sperm number; sleeping ≤ 6.5 h was associated with 4.6% (−10.5, 22.3) and 25.7% (−1.2, 60.1) reduction. Increase of the two parameters was found in those who changed sleep duration toward 7.0–7.5 h/day from 2013 to 2014. The U-shaped association was independent from PSQI and was replicated in another dataset of 1,346 males. No association found between sleep duration and reproductive hormone. Conclusions: Either restricted or excessive sleep may impair semen quality. Further research is needed to validate this finding. Citation: Chen Q, Yang H, Zhou N, Sun L, Bao H, Tan L, Chen H, Ling X, Zhang G, Huang L, Li L, Ma M, Yang H, Wang X, Zou P, Peng K, Liu T, Cui Z, Ao L, Roenneberg T, Zhou Z, Cao J. Inverse u-shaped association between sleep duration and semen quality: longitudinal observational study (MARHCS) in Chongqing, China. SLEEP 2016;39(1):79–86. PMID:26350472

Generalized Factorial Moments

NASA Astrophysics Data System (ADS)

Bialas, A.

2004-02-01

It is shown that the method of eliminating the statistical fluctuations from event-by-event analysis proposed recently by Fu and Liu can be rewritten in a compact form involving the generalized factorial moments.

Reply to comment by X. X. Zhang et al. on "Three-dimensional quantification of soil hydraulic properties using X-ray computed tomography and image-based modeling"

NASA Astrophysics Data System (ADS)

Tracy, Saoirse R.; Daly, Keith R.; Sturrock, Craig J.; Crout, Neil M. J.; Mooney, Sacha J.; Roose, Tiina

2016-07-01

In response to the comment raised by Zhang et al. (2016, doi: 10.1002/2015WR018432) we explore the differences in average velocity computed using slip and no-slip boundary conditions at the air water interface. We consider a porous medium in which the air phase acts to impede the movement of water rather than to lubricate it, a case closer to the observed distribution of water in our CT images. We find that, whilst the slip boundary condition may be a more accurate approximation, in cases where the air phase is seen to impede water movement the differences between the two approaches are negligible.

A Provably Secure RFID Authentication Protocol Based on Elliptic Curve for Healthcare Environments.

PubMed

Farash, Mohammad Sabzinejad; Nawaz, Omer; Mahmood, Khalid; Chaudhry, Shehzad Ashraf; Khan, Muhammad Khurram

2016-07-01

To enhance the quality of healthcare in the management of chronic disease, telecare medical information systems have increasingly been used. Very recently, Zhang and Qi (J. Med. Syst. 38(5):47, 32), and Zhao (J. Med. Syst. 38(5):46, 33) separately proposed two authentication schemes for telecare medical information systems using radio frequency identification (RFID) technology. They claimed that their protocols achieve all security requirements including forward secrecy. However, this paper demonstrates that both Zhang and Qi's scheme, and Zhao's scheme could not provide forward secrecy. To augment the security, we propose an efficient RFID authentication scheme using elliptic curves for healthcare environments. The proposed RFID scheme is secure under common random oracle model.

A three-dimensional spin-diffusion model for micromagnetics

PubMed Central

Abert, Claas; Ruggeri, Michele; Bruckner, Florian; Vogler, Christoph; Hrkac, Gino; Praetorius, Dirk; Suess, Dieter

2015-01-01

We solve a time-dependent three-dimensional spin-diffusion model coupled to the Landau-Lifshitz-Gilbert equation numerically. The presented model is validated by comparison to two established spin-torque models: The model of Slonzewski that describes spin-torque in multi-layer structures in the presence of a fixed layer and the model of Zhang and Li that describes current driven domain-wall motion. It is shown that both models are incorporated by the spin-diffusion description, i.e., the nonlocal effects of the Slonzewski model are captured as well as the spin-accumulation due to magnetization gradients as described by the model of Zhang and Li. Moreover, the presented method is able to resolve the time dependency of the spin-accumulation. PMID:26442796

Genetics Home Reference: X-linked acrogigantism

MedlinePlus

... sons. In females, the condition results from new ( de novo ) duplications involving the GPR101 gene that occur ... P, Oldfield EH, Bours V, Liu P, W de Herder W, Pellegata N, Lupski JR, Daly AF, ...

Genetics Home Reference: Donnai-Barrow syndrome

MedlinePlus

... Robson C, Liu T, MacLaughlin DT, Noonan KM, Russell MK, Walsh CA, Donahoe PK, Pober BR. Mutations ... Ragge NK, Thomas NS, Robinson DO, Noonan KM, Russell MK, Donnai D, Raymond FL, Walsh CA, Donahoe ...

VizieR Online Data Catalog: Lithium abundances of a large sample of red giants (Liu+, 2014)

NASA Astrophysics Data System (ADS)

Liu, Y. J.; Tan, K. F.; Wang, L.; Zhao, G.; Sato, B.; Takeda, Y.; Li, H. N.

2017-06-01

The sample stars analyzed here are comprised of 321 giants from the Okayama Planet Search Program (Sato et al. 2003ApJ...597L.157S) and 57 giants from the Xinglong Planet Search Program (Liu et al. 2008ApJ...672..553L). Both programs aim to detect planets around intermediate mass G type (and early K type) giants. The spectra were taken with the High Dispersion Echelle Spectrograph at Okayama Astrophysical Observatory (OAO), which was equipped at the coude focus of the 1.88 m telescope during 2008-2010. Before 2008 October, one CCD system with wavelength coverage of 5000-6200 Å was used, and after that the new mosaic 3 CCD system with wavelength a coverage of 4000-7540 Å replaced it. (2 data files).

Soft silicone rubber in phononic structures: Correct elastic moduli

NASA Astrophysics Data System (ADS)

Still, Tim; Oudich, M.; Auerhammer, G. K.; Vlassopoulos, D.; Djafari-Rouhani, B.; Fytas, G.; Sheng, P.

2013-09-01

We report on a combination of experiments to determine the elastic moduli of a soft poly (dimethylsiloxane) rubber that was utilized in a smart experiment on resonant phononic modes [Liu , ScienceSCIEAS0036-807510.1126/science.289.5485.1734 289, 1734 (2000)] and whose reported moduli became widely used as a model system in theoretical calculations of phononic materials. We found that the most peculiar hallmark of these values, an extremely low longitudinal sound velocity, is not supported by our experiments. Anyhow, performing theoretical band structure calculations, we can reproduce the surprising experimental findings of Liu even utilizing the correct mechanical parameters. Thus, the physical conclusions derived in the theoretical works do not require the use of an extremely low longitudinal velocity, but can be reproduced assuming only a low value of the shear modulus, in agreement with our experiments.

Modeling of the Radiation Belt Dynamics During the Two Largest Geomagnetic Storms of Solar Cycle 24

NASA Astrophysics Data System (ADS)

Zheng, Y.; Rastaetter, L.; Kuznetsova, M. M.

2016-12-01

In this paper, radiation belt response to the two largest geomagnetic storms of Solar Cycle 24 (17 March 2015 and the 22 June 2015) is investigated in detail. Even though both storms are primarily CME driven, each has its own complexities [Liu et al., 2015, Kataoka et al., 2015]. Using the CCMC's run-on-request system, modeling results using the RBE (Radiation Belt Environment) model within the SWMF (Space Weather Modeling Framework) and the RBE model coupled with the SWMF and RCM (Rice Convection Model, which takes the ring current's contribution into consideration) will be examined. Comparative and comprehensive analyses of the same event from two different models and of two events from the same model/model suite will be provided. Focus will be specially given to impacts of different solar wind drivers on radiation belt dynamics and to the coupling and interactions of different plasma populations/physical processes within the region. Liu, Ying D., H. Hu, R. Wang, Z. Yang, B., Zhu, Y. A., Liu, J. G. Luhmann, J. D. Richardson (2015), Plasma and Magnetic Field Characteristics of Solar Coronal Mass Ejections in Relation to Geomagnetic Storm Intensity and Variability, The Astrophysical Journal Letters, Volume 809, Issue 2, article id. L34, 6 pp. doi:10.1088/2041-8205/809/2/L34. Kataoka, R., D. Shiota, E. Kilpua, and K. Keika (2015), Pileup accident hypothesis of magnetic storm on 17 March 2015, Geophys. Res. Lett., 42, 5155-5161, doi:10.1002/2015GL064816.

Notes on recent approaches concerning the Kirchhoff-law-Johnson-noise-based secure key exchange

NASA Astrophysics Data System (ADS)

Kish, Laszlo B.; Horvath, Tamas

2009-08-01

We critically analyze the results and claims in [P.-L. Liu, Phys. Lett. A 373 (2009) 901]. We show that the strong security leak appeared in the simulations is only an artifact and not caused by “multiple reflections”. Since no wave modes exist at cable length of 5% of the shortest wavelength of the signal, no wave is present to reflect it. In the high wave impedance limit, the conditions used in the simulations are heavily unphysical (requiring cable diameters up to 28000 times greater than the measured size of the known universe) and the results are modeling artifacts due to the unphysical values. At the low cable impedance limit, the observed artifacts are due to violating the recommended (and tested) conditions by neglecting the cable capacitance restrictions and using about 100 times longer cable than recommended without cable capacitance compensation arrangement. We implement and analyze the general circuitry of Liu's circulator [P.-L. Liu, Phys. Lett. A 373 (2009) 901] and confirm that they are conceptually secure against passive attacks. We introduce an asymmetric, more robust version without feedback loop. Then we crack all these systems by an active attack: a circulator-based man-in-the middle attack. Finally, we analyze the proposed method to increase security by dropping only high-risk bits. We point out the differences between different types of high-risk bits and show the shortage of this strategy for some simple key exchange protocols.

Taxonomic Approach to the Tachinid Flies Dinera carinifrons (Fallén) (Diptera: Tachinidae) and Dinera fuscata Zhang and Shima using Molecular and Morphometric Data

PubMed Central

Lutovinovas, Erikas; Malenovský, Igor; Tóthová, Andrea; Ziegler, Joachim; Vaňhara, Jaromír

2013-01-01

Molecular phylogenetic and traditional morphometric methods were applied to examine six Palaearctic taxa of the taxonomically difficult tachinid fly genus Dinera Robineau-Desvoidy (Diptera: Tachinidae), with particular reference to D. carinifrons (Fallén) and D. fuscata Zhang and Shima. Results of a phylogenetic analysis based on the mitochondrial markers 12S and 16S rDNA and multivariate statistical analyses of 19 morphometric characters were used to delimit both species. A lectotype was designated for D. carinifrons to stabilize the nomenclature in the group. Dinera carinifrons has a transpalaearctic distribution and is present in Central Europe, especially in high altitudes of the Alps. It differs from the similar and closely related D. fuscata in that it has a slightly larger body size, a dense greyish microtrichosity on the body, and different head proportions. Dinera fuscata, as delimited here, is widespread in the Palaearctic region, including Europe. Slight differences in both molecular and morphometric characters were found between western (Europe and Iran) and eastern (China and Japan) populations of D. fuscata, which are interpreted as an intraspecific variation. Differential diagnosis between D. carinifrons and D. fuscata is provided in the form of a revised portion of the determination key to the Palaearctic Dinera by Zhang and Shima (2006). PMID:24787238

Controlling Self-Assembly in Al(110) Homoepitaxy

NASA Astrophysics Data System (ADS)

Tiwary, Yogesh; Fichthorn, Kristen

2010-03-01

Homoepitaxial growth on Al(110) exhibits nanoscale self-assembly into huts with well-defined (100) and (111) facets [1]. Although some of the diffusion mechanisms underlying this kinetic self-assembly were identified and incorporated into a two-dimensional model [2], we used density-functional theory (DFT) to identify many other mechanisms that are needed to describe the three-dimensional assembly seen experimentally [3]. We developed a three-dimensional kinetic Monte Carlo (KMC) model of Al(110) homoepitaxy. The inputs to the model were obtained from DFT [3,4]. Our model is in agreement with experimentally observed trends for this system. We used KMC to predict self-assembly under various growth conditions. To achieve precise placement of Al nanohuts, we simulated thermal-field-directed assembly [5]. Our results indicate that this technique can be used to create uniform arrays of nanostructures. [1] F. Buatier de Mongeot, W. Zhu, A. Molle, R. Buzio, C. Boragno, U. Valbusa, E. Wang, and Z. Zhang, Phys. Rev. Lett. 91, 016102 (2003). [2] W. Zhu, F. Buatier de Mongeot, U. Valbusa, E. G. Wang, and Z. Y. Zhang, Phys. Rev. Lett. 92, 106102 (2004). [3] Y. Tiwary and K. A. Fichthorn, submitted to Phys. Rev. B. [4] Y. Tiwary and K. A. Fichthorn, Phys. Rev. B 78, 205418 (2008). [5] C. Zhang and R. Kalyanaraman, Appl. Phys. Lett. 83, 4827 (2003).

Building bridges with the West

NASA Astrophysics Data System (ADS)

Banks, Michael

2017-06-01

Michael Banks talks to theoretical condensed-matter physicist Fuchun Zhang, director of the new Kavli Institute of Theoretical Sciences in Beijing, about the challenges of attracting top-class talent to China

Genetics Home Reference: isolated lissencephaly sequence

MedlinePlus

... This Page Dobyns WB. The clinical patterns and molecular genetics of lissencephaly and subcortical band heterotopia. Epilepsia. 2010 ... Feb 23. Review. Citation on PubMed Liu JS. Molecular genetics of neuronal migration disorders. Curr Neurol Neurosci Rep. ...

Genetics Home Reference: Bowen-Conradi syndrome

MedlinePlus

... Page Armistead J, Khatkar S, Meyer B, Mark BL, Patel N, Coghlan G, Lamont RE, Liu S, Wiechert J, ... or Free article on PubMed Central Armistead J, Patel N, Wu X, Hemming R, Chowdhury B, Basra ...

ARM - Midlatitude Continental Convective Clouds - Single Column Model Forcing (xie-scm_forcing)

DOE Data Explorer

Xie, Shaocheng; McCoy, Renata; Zhang, Yunyan

2012-10-25

The constrained variational objective analysis approach described in Zhang and Lin [1997] and Zhang et al. [2001]was used to derive the large-scale single-column/cloud resolving model forcing and evaluation data set from the observational data collected during Midlatitude Continental Convective Clouds Experiment (MC3E), which was conducted during April to June 2011 near the ARM Southern Great Plains (SGP) site. The analysis data cover the period from 00Z 22 April - 21Z 6 June 2011. The forcing data represent an average over the 3 different analysis domains centered at central facility with a diameter of 300 km (standard SGP forcing domain size), 150 km and 75 km, as shown in Figure 1. This is to support modeling studies on various-scale convective systems.

Model for growth of fractal solid state surface and possibility of its verification by means of atomic force microscopy

NASA Astrophysics Data System (ADS)

Kulikov, D. A.; Potapov, A. A.; Rassadin, A. E.; Stepanov, A. V.

2017-10-01

In the paper, methods of verification of models for growth of solid state surface by means of atomic force microscopy are suggested. Simulation of growth of fractals with cylindrical generatrix on the solid state surface is presented. Our mathematical model of this process is based on generalization of the Kardar-Parisi-Zhang equation. Corner stones of this generalization are both conjecture of anisotropy of growth of the surface and approximation of small angles. The method of characteristics has been applied to solve the Kardar-Parisi-Zhang equation. Its solution should be considered up to the gradient catastrophe. The difficulty of nondifferentiability of fractal initial generatrix has been overcome by transition from a mathematical fractal to a physical one.

When Charged Black Holes Merge

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-08-01

Most theoretical models assume that black holes arent charged. But a new study shows that mergers of charged black holes could explain a variety of astrophysical phenomena, from fast radio bursts to gamma-ray bursts.No HairThe black hole no hair theorem states that all black holes can be described by just three things: their mass, their spin, and their charge. Masses and spins have been observed and measured, but weve never measured the charge of a black hole and its widely believed that real black holes dont actually have any charge.That said, weve also never shown that black holes dont have charge, or set any upper limits on the charge that they might have. So lets suppose, for a moment, that its possible for a black hole to be charged. How might that affect what we know about the merger of two black holes? A recent theoretical study by Bing Zhang (University of Nevada, Las Vegas) examines this question.Intensity profile of a fast radio burst, a sudden burst of radio emission that lasts only a few milliseconds. [Swinburne Astronomy Productions]Driving TransientsZhangs work envisions a pair of black holes in a binary system. He argues that if just one of the black holes carries charge possibly retained by a rotating magnetosphere then it may be possible for the system to produce an electromagnetic signal that could accompany gravitational waves, such as a fast radio burst or a gamma-ray burst!In Zhangs model, the inspiral of the two black holes generates a global magnetic dipole thats perpendicular to the plane of the binarys orbit. The magnetic flux increases rapidly as the separation between the black holes decreases, generating an increasingly powerful magnetic wind. This wind, in turn, can give rise to a fast radio burst or a gamma-ray burst, depending on the value of the black holes charge.Artists illustration of a short gamma-ray burst, thought to be caused by the merger of two compact objects. [ESO/A. Roquette]Zhang calculates lower limits on the charge necessary to produce each phenomenon. For a 10-solar-mass black hole, he finds that the merger can generate a fast radio burst if the black holes charge is more than ~1012 Coulombs (roughly one billion times the charge that travels through a AA battery from full to empty). If its charge is more than ~1016 Coulombs, it can generate a gamma-ray burst.Limits on ChargeZhangs calculations are not just useful in the hypothetical scenario where black holes are charged. They could, in fact, be a way of testing whether black holes are charged.As we accumulate future gravitational-wave observations (and with two observations by LIGO already announced, it seems likely that there will be many more), we will grow a larger sample of follow-up observations in radio through gamma-ray wavelengths. Our detections or our lack of detections of fast radio bursts or gamma-ray bursts associated with these black-hole mergers will allow us to set some of the first real limits on the charge of black holes.CitationBing Zhang 2016 ApJ 827 L31. doi:10.3847/2041-8205/827/2/L31

New Ultra-Compact Dwarf Galaxies in Clusters

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-02-01

How do ultra-compact dwarf galaxies (UCDs) galaxies that are especially small and dense form and evolve? Scientists have recently examined distant galaxy clusters, searching for more UCDs to help us answer this question.Origins of DwarfsIn recent years we have discovered a growing sample of small, very dense galaxies. Galaxies that are tens to hundreds of light-years across, with masses between a million and a billion solar masses, fall into category of ultra-compact dwarfs (UCDs).An example of an unresolved compact object from the authors survey that is likely an ultra-compact dwarf galaxy. [Adapted from Zhang Bell 2017]How do these dense and compact galaxies form? Two possibilities are commonly suggested:An initially larger galaxy was tidally stripped during interactions with other galaxies in a cluster, leaving behind only its small, dense core as a UCD.UCDs formed as compact galaxies at very early cosmic times. The ones living in a massive dark matter halo may have been able to remain compact over time, evolving into the objectswe see today.To better understand which of these formation scenarios applies to which galaxies, we need a larger sample size! Our census of UCDs is fairly limited and because theyare small and dim, most of the ones weve discovered are in the nearby universe. To build a good sample, we need to find UCDs at higher redshifts as well.A New SampleIn a recent study, two scientists from University of Michigan have demonstrated how we might find more UCDs. Yuanyuan Zhang (also affiliated with Fermilab) and Eric Bell used the Cluster Lensing and Supernova Survey with Hubble (CLASH) to search 17 galaxy clusters at intermediate redshifts of 0.2 z 0.6, looking for unresolved objects that might be UCDs.The mass and size distributions of the UCD candidates reported in this study, in the context of previously known nuclear star clusters, globular clusters (GCs), UCDs, compact elliptical galaxies (cEs), and dwarf galaxies. [Zhang Bell 2017]Zhang and Bell discovered a sample of compact objects grouped around the central galaxies of the clusters that are consistent with ultra-compact galaxies. The inferred sizes (many around 600 light-years in radius) and masses (roughly one billion solar masses) of these objects suggest that this sample may contain some of the densest UCDs discovered to date.The properties of this new set of UCD candidates arent enough to distinguish between formation scenarios yet, but the authors argue that if we find more such galaxies, we will be able to use the statistics of their spatial and color distributions to determine how they were formed.Zhang and Bell estimate that the 17 CLASH clusters studied in this work each contain an average of 2.7 of these objects in the central million light-years of the cluster. The authors work here suggests that searching wide-field survey data for similar discoveries is a plausible way to increase our sample of UCDs. This will allow us to statistically characterize these dense, compact galaxies and better understand their origins.CitationYuanyuan Zhang and Eric F. Bell 2017 ApJL 835 L2. doi:10.3847/2041-8213/835/1/L2

Hanyu Zhang | NREL

Science.gov Websites

investigate approaches that can make 2D materials with better functionality by studying the energetic ., Engineering Chemically-Exfoliated Large-Area Two-Dimensional MoS2 Nanolayers with Porphyrins for Improved

Genetics Home Reference: Pyle disease

MedlinePlus

... of print] Citation on PubMed Haraguchi R, Kitazawa R, Mori K, Tachibana R, Kiyonari H, Imai Y, Abe T, ... K, Kiviranta R, Solban N, Liu J, Brommage R, Boduroglu K, Bonafé L, Campos-Xavier B, Dikoglu E, Eastell ...

Dependency distance minimization in understanding of ambiguous structure. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Zhao, Yiyi

2017-07-01

Dependency Distance, proposed by Hudson [1], calculated by Liu [2,3], is an important concept in Dependency Theory. It can be used as a measure of the syntactic difficulty, and lots of research [2,4] have testified the universal of Dependency Distance in various languages. Human languages seem to present a preference for short dependency distance, which may be explained in terms of general cognitive constraint of limited working memory [5]. Psychological experiments in English, German, Russian and Chinese support the hypothesis that Dependency Distance minimization (DDM) make languages to evolve into some syntactic patterns to reduce memory burden [6-9]. The study of psychology focuses on the process and mechanism of syntactic structure selection in speech comprehension. In many speech comprehension experiments [10], ambiguous structure is an important experimental material.

The carbon-14 spike in the 8th century was not caused by a cometary impact on Earth

NASA Astrophysics Data System (ADS)

Usoskin, Ilya G.; Kovaltsov, Gennady A.

2015-11-01

A mysterious increase of radiocarbon 14 C ca. 775 AD in the Earth's atmosphere has been recently found by Miyake et al. (Miyake, F., Nagaya, K., Masuda, K., Nakamura, T. [2012]. Nature, 486, 240). A possible source of this event has been discussed widely, the most likely being an extreme solar energetic particle event. A new exotic hypothesis has been presented recently by Liu et al. (Liu, Y. [2014]. Sci. Rep., 4, 3728) who proposed that the event was caused by a cometary impact on Earth bringing additional 14 C to the atmosphere. Here we calculated a realistic mass and size of such a comet to show that it would have been huge (≈100 km across and 1017-1020 g of mass) and would have produced a disastrous geological/biological impact on Earth. The absence of an evidence for such a dramatic event makes this hypothesis invalid.

Relativistic distorted-wave collision strengths for Δn = 0 transitions in the 67 Li-like, F-like and Na-like ions with 26 ≤ Z ≤ 92

NASA Astrophysics Data System (ADS)

Fontes, Christopher J.; Zhang, Hong Lin

2017-01-01

Relativistic distorted-wave collision strengths have been calculated for all possible Δn = 0 transitions, where n denotes the valence shell of the ground level, in the 67 Li-like, F-like and Na-like ions with Z in the range 26 ≤ Z ≤ 92. This choice produces 3 transitions with n = 2 in the Li-like and F-like ions, and 10 transitions with n = 3 in the Na-like ions. For the Li-like and F-like ions, the calculations were made for the six final, or scattered, electron energies E‧ = 0.008 , 0.04 , 0.10 , 0.21 , 0.41, and 0.75, where E‧ is in units of Zeff2 Ry with Zeff = Z - 1.66 for Li-like ions and Zeff = Z - 6.667 for F-like ions. For the Na-like ions, the calculations were made for the six final electron energies E‧ = 0.0025 , 0.015 , 0.04 , 0.10 , 0.21, and 0.40, with Zeff = Z - 8.34. In the present calculations, an improved "top-up" method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb-Bethe approximation used in previous works by Zhang, Sampson and Fontes [H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 31; H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 48 (1991) 25; D.H. Sampson, H.L. Zhang, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 209]. In those previous works, collision strengths were also provided for Li-, F- and Na-like ions, but for a more comprehensive set of transitions. The collision strengths covered in the present work should be more accurate than the corresponding data given in those previous works and are presented here to replace those earlier results.

Relativistic distorted-wave collision strengths for Δn = 0 transitions in the 67 Li-like, F-like and Na-like ions with 26 ≤ Z ≤ 92

DOE PAGES

Fontes, Christopher J.; Zhang, Hong Lin

2017-01-01

We calculated relativistic distorted-wave collision strength for all possible Δn=0 transitions, where n denotes the valence shell of the ground level, in the 67 Li-like, F-like and Na-like ions with Z in the range 26 ≤ Z ≤92. This choice produces 3 transitions with n=2 in the Li-like and F-like ions, and 10 transitions with n=3 in the Na-like ions. Moreover, for the Li-like and F-like ions, the calculations were made for the six final, or scattered, electron energies E'=0.008,0.04,0.10,0.21,0.41, and 0.75, where E' is in units of Zmore » $$2\\atop{eff}$$ Ry with Z eff = Z- 1.66 for Li-like ions and Z eff= Z- 6.667 for F-like ions. For the Na-like ions, the calculations were made for the six final electron energies E'=0.0025,0.015,0.04,0.10,0.21, and 0.40, with Z eff = Z- 8.34. In the present calculations, an improved “top-up” method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb–Bethe approximation used in previous works by Zhang, Sampson and Fontes [H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 31; H.L. Zhang, D.H. Sampson, C.J. Fontes, At. Data Nucl. Data Tables 48 (1991) 25; D.H. Sampson, H.L. Zhang, C.J. Fontes, At. Data Nucl. Data Tables 44 (1990) 209]. In those previous works, collision strengths were also provided for Li-, F- and Na-like ions, but for a more comprehensive set of transitions. Finally, the collision strengths covered in the present work should be more accurate than the corresponding data given in those previous works and are presented here to replace those earlier results.« less

Genetics Home Reference: hereditary hyperekplexia

MedlinePlus

... Howell OW, Vanbellinghen JF, Rees MI, Chung SK, Lynch JW. New hyperekplexia mutations provide insight into glycine ... Zhang Y, Bode A, Nguyen B, Keramidas A, Lynch JW. Investigating the Mechanism by Which Gain-of- ...

Molecular modeling studies of 1,4-dihydro-4-oxoquinoline ribonucleosides with anti-HSV-1 activity

NASA Astrophysics Data System (ADS)

Yoneda, Julliane Diniz; Albuquerque, Magaly Girão; Leal, Kátia Zaccur; Seidl, Peter Rudolf; de Alencastro, Ricardo Bicca

2011-12-01

Eight human herpes viruses ( e.g., herpes simplex, varicella-zoster, Epstein-Barr, cytomegalovirus, Kaposi's sarcoma) are responsible for several diseases from sub-clinic manifestations to fatal infections, mostly in immunocompromised patients. The major limitations of the currently available antiviral drug therapy are drug resistance, host toxicity, and narrow spectrum of activity. However, some non-nucleoside 1,4-dihydro-4-oxoquinoline derivatives ( e.g., PNU-183792) [4] shows broad spectrum antiviral activity. We have developed molecular modeling studies, including molecular docking and molecular dynamics simulations, based on a model proposed by Liu and co-workers [14] in order to understand the mechanism of action of a 6-chloro substituted 1,4-dihydro-4-oxoquinoline ribonucleoside, synthesized by the synthetic group, which showed anti-HSV-1 activity [9]. The molecular docking simulations confirmed the Liu's model showing that the ligand needs to dislocate template residues from the active site in order to interact with the viral DNA polymerase enzyme, reinforcing that the interaction with the Val823 residue is pivotal for the inhibitory activity of non-nucleoside 1,4-dihydro-4-oxoquinoline derivatives, such as PNU-183792, with the HSV-1. The molecular dynamics simulations showed that the 6-chloro-benzyl group of PNU-183792 maintains its interaction with residues of the HSV-1 DNA polymerase hydrophobic pocket, considered important according to the Liu's model, and also showed that the methyl group bounded to the nitrogen atom from PNU-183792 is probably contributing to a push-pull effect with the carbonyl group.

Distributed approximating functional fit of the H{sub 3} {ital ab initio} potential-energy data of Liu and Siegbahn

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frishman, A.; Hoffman, D.K.; Kouri, D.J.

1997-07-01

We report a distributed approximating functional (DAF) fit of the {ital ab initio} potential-energy data of Liu [J. Chem. Phys. {bold 58}, 1925 (1973)] and Siegbahn and Liu [{ital ibid}. {bold 68}, 2457 (1978)]. The DAF-fit procedure is based on a variational principle, and is systematic and general. Only two adjustable parameters occur in the DAF leading to a fit which is both accurate (to the level inherent in the input data; RMS error of 0.2765 kcal/mol) and smooth ({open_quotes}well-tempered,{close_quotes} in DAF terminology). In addition, the LSTH surface of Truhlar and Horowitz based on this same data [J. Chem. Phys.more » {bold 68}, 2466 (1978)] is itself approximated using only the values of the LSTH surface on the same grid coordinate points as the {ital ab initio} data, and the same DAF parameters. The purpose of this exercise is to demonstrate that the DAF delivers a well-tempered approximation to a known function that closely mimics the true potential-energy surface. As is to be expected, since there is only roundoff error present in the LSTH input data, even more significant figures of fitting accuracy are obtained. The RMS error of the DAF fit, of the LSTH surface at the input points, is 0.0274 kcal/mol, and a smooth fit, accurate to better than 1cm{sup {minus}1}, can be obtained using more than 287 input data points. {copyright} {ital 1997 American Institute of Physics.}« less

EDITORIAL: Nanotechnology in vivo Nanotechnology in vivo

NASA Astrophysics Data System (ADS)

Demming, Anna

2010-04-01

Since the development of x-rays the ability to image inside our bodies has provided medicine with a potent diagnostic tool, as well as fascinating us with the eerie evidence of our mechanistic mortality. In December 2008 Osamu Shimomura, Martin Chalfie and Roger Y Tsien received a Nobel Prize for the discovery and development of the green fluorescent protein. The award recognised a new discovery that further facilitated our abilities to follow cellular activities and delve deeper into the workings of living organisms. Since the first observation of green fluorescent protein in jelly fish over thirty years ago, quantum dots have emerged as a potential alternative tool for imaging [1]. The advantages of quantum dots over organic dyes and fluorescent proteins include intense luminescence, high molar extinction coefficient, resistance to photobleaching, and broad excitation with narrow emission bands. However, one drawback for biological applications has been the layer of hydrophobic organic ligands often present at the surface as a result of the synthesis procedures. One solution to improve the solubility of quantum dots has been to conjugate them with a hydrophilic substance, as reported by Nie et al [2]. Chitosan is a hydrophilic, non-toxic, biocompatible and biodegradable substance and has been conjugated with quantum dots such as CdSe-ZnS [2] for bioassays and intracellular labelling. As well as luminescence, different nanoparticles present a variety of exceptional properties that render them useful in a range of bio applications, including MRI, drug delivery and cancer hyperthermia therapy. The ability to harness these various attributes in one system was reported by researchers in China, who incorporated magnetic nanoparticles, fluorescent quantum dots and pharmaceutical drugs into chitosan nanoparticles for multifunctional smart drug delivery systems [3]. More recently silicon quantum dots have emerged as a less cytotoxic alternative to CdSe for bio-imaging labels [4]. A surface hydroxyl group renders silicon quantum dots soluble in water and the photoluminescence can be made stable with oxygen-passivation. In addition, researchers in Japan have demonstrated how the initially modest yield in the preparation of silicon quantum dots can be improved to tens of milligrams per batch, thus further promoting their application in bio-imaging [5]. In the search for non-toxic quantum dots, researchers at the Amrita Centre for Nanoscience in India have prepared heavy metal-free quantum dot bio-probes based on single phase ZnS [6]. The quantum dots are selectively doped with metals, transition metals and halides to provide tuneable luminescence properties, and they are surface conjugated with folic acid for cancer targeting. The quantum dots were demonstrated to be water-soluble, non-toxic in normal and cancer cell lines, and have bright, tuneable luminescence. So far most of the quantum dots developed for bio-imaging have had excitation and emission wavelengths in the visible spectrum, which is highly absorbed by tissue. This limits imaging with these quantum dots to superficial tissues. This week, researchers in China and the US reported work developing functionalized dots for in vivo tumour vasculature in the infrared part of the spectrum [7]. In addition the quantum dots were functionalised with glycine-aspartic acid (RGD) peptides, which target the vasculature of almost all types of growing tumours, unlike antibody- or aptamer-mediated targeting strategies that are specific to a particular cancer type. In this issue, researchers in China and the US demonstrate a novel type of contrast agent for ultrasonic tumour imaging [8]. Contrast-enhanced ultrasonic tumour imaging extends the diagnostic and imaging capabilities of traditional techniques. The use of nanoparticles as ultrasound contrast agents exploits the presence of open pores in the range of 380 to 780 nm in tumour blood vessels, which enhance the permeability and retention of nanoparticles in the tumour vasculature. However, previous reports on techniques to generate nanobubbles have either been slow or problematic due to the resulting development of cardiac dimension reduction, hypotension and tachycardia. Xing and colleagues have now demonstrated the use of polyoxyethylene 40 stearate, which is known to be biocompatible, degradable and non-toxic, as an alternative surfactant for generating nanobubbles. In the early 1980s scanning probe micrographs of nanosized features unleashed the power of imaging to push forward the science of structures and mechanisms at the nanoscale. The continued development of new and increasingly sophisticated nanoparticles and systems looks set to empower medicine in the same way, providing further means to exploit the mechanistic nature of biological organisms for better health and longevity. References [1] Leon R, Petroff P M, Leonard D and Fafard S 1995 Science 267 1966-8 [2] Nie Q, Tan W B and Zhang Y 2006 Nanotechnology 17 140-4 [3] Li L, Chen D, Zhang Y, Deng Z, Ren X, Meng X, Tang F, Ren J and Zhang L 2007 Nanotechnology 18 405102 [4] Fujioka K et al 2008 Nanotechnology 19 415102 [5] Shinoda K, Yangisawa S, Sato K amd Hirakuri K 2006 J. Cryst. Growth 288 84-6 [6] Manzoor K, Johny S, Thomas D, Setua S, Menon D and Nair S 2009 Nanotechnology 20 065102 [7] Hu R, Yong K-T, Roy I, Ding H, Law W-C, Cai H, Zhang X, Vathy L A, Bergey E J and Prasad P N 2010 Nanotechnology 21 145105 [8] Xing, Z, Ke H, Wang J, Zhao B, Yue X, Dai Z and Liu J 2010 Nanotechnology 21 145607

Genetics Home Reference: Stargardt macular degeneration

MedlinePlus

... called the macula. The macula is responsible for sharp central vision, which is needed for detailed tasks ... STARGARDT DISEASE 3 Sources for This Page Molday RS, Zhang K. Defective lipid transport and biosynthesis in ...

Diet-derived microRNAs: unicorn or silver bullet?

PubMed

Witwer, Kenneth W; Zhang, Chen-Yu

2017-01-01

In ancient lore, a bullet cast from silver is the only effective weapon against monsters. The uptake of active diet-derived microRNAs (miRNAs) in consumers may be the silver bullet long sought after in nutrition and oral therapeutics. However, the majority of scientists consider the transfer and regulation of consumer's gene activity by these diet-derived miRNAs to be a fantasy akin to spotting a unicorn. Nevertheless, groups like Dr. Chen-Yu Zhang's lab in Nanjing University have stockpiled breathtaking amounts of data to shoot down these naysayers. Meanwhile, Dr. Ken Witwer at John Hopkins has steadfastly cautioned the field to beware of fallacies caused by contamination, technical artifacts, and confirmation bias. Here, Dr. Witwer and Dr. Zhang share their realities of dietary miRNAs by answering five questions related to this controversial field.

Optical conductivity of cuprates in the pseudogap state: Yang-Rice-Zhang model and antiferromagnetic spin waves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Navinder; Sharma, Raman

In the underdoped regime of the cuprate phase diagram, the modified version of the Resonance Valence Bond (RVB) model by Yang, Rice and Zhang (YRZ) captures the strong electronic correlation effects very well as corroborated by the ARPES and many other experiments. However, under a non-equilibrium transport setting, YRZ says nothing about the scattering mechanisms of the charge carriers. In the present investigation we include, in a very simplified way, the scattering of charge carriers due to antiferromagnetic type spin waves (ASW). The effect of ASW excitations on conductivity has been studied by changing combined life times of the includedmore » process. It has been found that there is a qualitative change in the conductivity in the right direction. The theoretical conductivity reproduces qualitatively the experimental one.« less

Non-Zhang-Rice Singlet Character of the First Ionization State of T-CuO

NASA Astrophysics Data System (ADS)

Adolphs, Clemens P. J.; Moser, Simon; Sawatzky, George A.; Berciu, Mona

2016-02-01

We argue that tetragonal CuO (T-CuO) has the potential to finally settle long-standing modeling issues for cuprate physics. We compare the one-hole quasiparticle (qp) dispersion of T-CuO to that of cuprates, in the framework of the strongly correlated (Ud d→∞ ) limit of the three-band Emery model. Unlike in CuO2 , magnetic frustration in T-CuO breaks the C4 rotational symmetry and leads to strong deviations from the Zhang-Rice singlet picture in parts of the reciprocal space. Our results are consistent with angle-resolved photoemission spectroscopy data but in sharp contradiction to those of a one-band model previously suggested for them. These differences identify T-CuO as an ideal material to test a variety of scenarios proposed for explaining cuprate phenomenology.

[ZHANG Tangfa's characteristics of acupuncture academic ideology and clinical treatment of syndrome differentiation].

PubMed

Zhang, Hongxing

2015-10-01

Through collecting and sorting of works, literature and medical cases regarding professor ZHANG Tangfa, it is found that his acupuncture academic ideology and clinical treatment of syndrome differentiation can be summarized as: tracing the source and paying attention to basic theory, especially the meridian theory and conception vessel and governor vessel; focusing on acupuncture manipulation and emphasizing acupuncture basic skills; highly valuing treating spirit, acquiring and maintaining needling sensation; underlining "three differentiations" that is consisted of syndrome differentiation, disease differentiation and meridian differentiation to guide the clinical prescriptions of acupoints; exploring and ingenious use of scalp acupuncture; being concerned on research of difficult and complicated diseases; advocating comparative studies to optimize the clinical treatment plan; proposing the combination of Chinese and western medicine, including diagnosis, treatment and basic theory, to improve the clinical therapeutic effects of acupuncture.

Upgrade of absolute extreme ultraviolet diagnostic on J-TEXT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, X. L.; Cheng, Z. F., E-mail: chengfe@hust.edu.cn; Hou, S. Y.

The absolute extreme ultraviolet (AXUV) diagnostic system is used for radiation observation on J-TEXT tokamak [J. Zhang, G. Zhuang, Z. J. Wang, Y. H. Ding, X. Q. Zhang, and Y. J. Tang, Rev. Sci. Instrum. 81, 073509 (2010)]. The upgrade of the AXUV system is aimed to improve the spatial resolution and provide a three-dimensional image on J-TEXT. The new system consists of 12 AXUV arrays (4 AXUV16ELG arrays, 8 AXUV20ELG arrays). The spatial resolution in the cross-section is 21 mm for the AXUV16ELG arrays and 17 mm for the AXUV20ELG arrays. The pre-amplifier is also upgraded for a highermore » signal to noise ratio. By upgrading the AXUV imaging system, a more accurate observation on the radiation information is obtained.« less

Why are some HIV/AIDS patients reluctant to receive antiviral therapy as soon as possible in China?

PubMed

Sun, Yang; Lu, Hongzhou

2014-06-01

In more than 20 years of medical practice, a surprising phenomenon has often occurred: some patients with acquired immunodeficiency syndrome (AIDS) decide not to go to the hospital and they do not let others know that they are suffering from the disease unless they believe that they are dieing. Zhang Shan (a pseudonym) is one such patient with human immunodeficiency virus (HIV)/AIDS who was reluctant to receive antiviral therapy as soon as possible, and this paper shares Zhang's story as he related it. Clearly, there are numerous views as to why patients in China behave as Zhang did. Presented here are several reasons, including society, history, morality and ideology, family, and education. Although all of these reasons do play a role, the patient's mindset and behavior is the most significant reason for a patient's reluctance to seek treatment or disclose his/her status. If the individual patient's mindset and behavior are not dealt with effectively, then HIV/AIDS can continue to spread and threaten additional lives and even the fabric of society. This paper analyzes the reasons why patients are hesitant to receive antiviral therapy, but this paper also suggests steps healthcare personnel can take to encourage patients to seek treatment. Such steps can save the lives of current patients with HIV/AIDS. In addition, sound public health measures and a rational approach to treatment are important to helping potential patients with HIV/AIDS.

DRINKING WATER ARSENIC AND PERINATAL OUTCOMES

EPA Science Inventory

Drinking Water Arsenic and Perinatal Outcomes
DT Lobdell, Z Ning, RK Kwok, JL Mumford, ZY Liu, P Mendola

Many studies have documented an association between drinking water arsenic (DWA) and cancer, vascular diseases, and dermatological outcomes, but few have investigate...

Scymnus camptodromus (Coleoptera: Coccinellidae) larval development and predation of hemlock woolly adelgid (Hemiptera: Adelgidae)

Treesearch

Samita Limbu; Melody A. Keena; David Long; Nancy Ostiguy; Kelli Hoover

2015-01-01

Development time and prey consumption of Scymnus (Neopullus) camptodromus Yu and Liu (Coleoptera: Coccinellidae) larvae by instar, strain, and temperature were evaluated. S. camptodromus, a specialist predator of hemlock woolly adelgid Adelges tsugae (Annand) (Hemiptera:...

One new species of the subgenus Xizicus (Zangxizicus) (Orthoptera: Tettigoniidae: Meconematinae) from China.

PubMed

Lin, Chang Yan; Xia, Su Cai; Ming, Shi Fu

2016-09-26

The paper reports one new species of the tribe Meconematini, Xizicus (Zangxizicus), curvus Chang & Shi sp. nov., and supplies the character photographs of the new species and Xizicus(Zangxizicus) tibeticus Wang, Jing, Liu & Li, 2014.

SLAC All Access: X-ray Microscope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nelson, Johanna; Liu, Yijin

2012-08-14

SLAC physicists Johanna Nelson and Yijin Liu give a brief overview of the X-ray microscope at the Stanford Synchrotron Radiation Lightsource (SSRL) that is helping improve rechargeable-battery technology by letting researchers peek into the inner workings of batteries as they operate.

SLAC All Access: X-ray Microscope

ScienceCinema

Nelson, Johanna; Liu, Yijin

2018-01-16

SLAC physicists Johanna Nelson and Yijin Liu give a brief overview of the X-ray microscope at the Stanford Synchrotron Radiation Lightsource (SSRL) that is helping improve rechargeable-battery technology by letting researchers peek into the inner workings of batteries as they operate.

Deciphering the Ubiquitin Code.

PubMed

Dittmar, Gunnar; Selbach, Matthias

2017-03-02

In this issue of Molecular Cell, Zhang et al. (2017) systematically identify proteins interacting with all possible di-ubiquitin linkages, thus providing a catalog of readers of the ubiquitin code. Copyright © 2017 Elsevier Inc. All rights reserved.

Dubbing SAGA unveils new epigenetic crosstalk.

PubMed

Pijnappel, W W M Pim; Timmers, H Th Marc

2008-02-01

In a recent issue of Molecular Cell, two independent studies (Zhang et al., 2008; Zhao et al., 2008) provide compelling evidence that targeted deubiquitylation of histones is intimately linked to transcription activation, epigenetic regulation, and cancer progression.

Genetics Home Reference: atopic dermatitis

MedlinePlus

... JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa ... J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, ...

Host range specificity of Scymnus camptodromus (Coleoptera: Coccinellidae), a predator of hemlock woolly adelgid (Hemiptera: Adelgidae)

Treesearch

Samita Limbu; Katie Cassidy; Melody Keena; Patrick Tobin; Kelli Hoover

2015-01-01

Scymnus (Neopullus) camptodromus Yu and Liu (Coleoptera: Coccinellidae) was brought to the United States from China as a potential biological control agent for hemlock woolly adelgid (Adelges tsugae Annand) (Hemiptera: Adelgidae). Scymnus camptodromus phenology is...

Identification of Metastatic Tumor Stem Cell

DTIC Science & Technology

2011-09-01

Aya Kobayashi, Bo Xia, Misako Watabe, Sudha K Pai, Shigeru Hirota, Fei Xing, Wen Liu, Puspa R Pandey, Koji Fukuda, Vishnu Modur, Arnab Ghosh, Andrew...Xing, Puspa R. Pandey, Koji Fukuda, Megumi Iiizumi, Kounosuke Watabe. Hyaluronan synthase 2 promotes tumor progression by stimulating interaction of

Expressing the sense of Congress that China release democratic activist Liu Xiaobo from imprisonment.

THOMAS, 111th Congress

Rep. Minnick, Walter [D-ID-1

2009-06-12

Senate - 10/01/2009 Received in the Senate and referred to the Committee on Foreign Relations. (All Actions) Tracker: This bill has the status Agreed to in HouseHere are the steps for Status of Legislation:

How Is Hypoparathyroidism Treated?

MedlinePlus

... treatment of hypoparathyroidism. Journal of Clinical Endocrinology and Metabolism, 83 , 3480-3486. Winer, K. K., Zhang, B., Shrader, J. A., Peterson, D., Smith, M., Albert, P. S., et al. (2012). Synthetic human parathyroid hormone 1-34 replacement therapy: A randomized ...

Ames Lab 101: Real-Time 3D Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Song

2010-08-02

Ames Laboratory scientist Song Zhang explains his real-time 3-D imaging technology. The technique can be used to create high-resolution, real-time, precise, 3-D images for use in healthcare, security, and entertainment applications.

Ames Lab 101: Real-Time 3D Imaging

ScienceCinema

Zhang, Song

2017-12-22

Ames Laboratory scientist Song Zhang explains his real-time 3-D imaging technology. The technique can be used to create high-resolution, real-time, precise, 3-D images for use in healthcare, security, and entertainment applications.

76 FR 11798 - National Center for Research Resources; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-03

... Blvd., 1064, Bethesda, MD 20892-4874 (Telephone Conference Call). Contact Person: Guo Zhang, PhD... Health, 6701 Democracy Blvd., Dem. 1, Room 1064, MSC 4874, Bethesda, MD 20892-4874, 301-435-0812, zhanggu...

Generalized One-Band Model Based on Zhang-Rice Singlets for Tetragonal CuO.

PubMed

Hamad, I J; Manuel, L O; Aligia, A A

2018-04-27

Tetragonal CuO (T-CuO) has attracted attention because of its structure similar to that of the cuprates. It has been recently proposed as a compound whose study can give an end to the long debate about the proper microscopic modeling for cuprates. In this work, we rigorously derive an effective one-band generalized t-J model for T-CuO, based on orthogonalized Zhang-Rice singlets, and make an estimative calculation of its parameters, based on previous ab initio calculations. By means of the self-consistent Born approximation, we then evaluate the spectral function and the quasiparticle dispersion for a single hole doped in antiferromagnetically ordered half filled T-CuO. Our predictions show very good agreement with angle-resolved photoemission spectra and with theoretical multiband results. We conclude that a generalized t-J model remains the minimal Hamiltonian for a correct description of single-hole dynamics in cuprates.

Exact short-time height distribution for the flat Kardar-Parisi-Zhang interface

NASA Astrophysics Data System (ADS)

Smith, Naftali R.; Meerson, Baruch

2018-05-01

We determine the exact short-time distribution -lnPf(" close=")H ,t )">H ,t =Sf(H )/√{t } of the one-point height H =h (x =0 ,t ) of an evolving 1 +1 Kardar-Parisi-Zhang (KPZ) interface for flat initial condition. This is achieved by combining (i) the optimal fluctuation method, (ii) a time-reversal symmetry of the KPZ equation in 1 +1 dimension, and (iii) the recently determined exact short-time height distribution -lnPst(H ) of the latter, one encounters two branches: an analytic and a nonanalytic. The analytic branch is nonphysical beyond a critical value of H where a second-order dynamical phase transition occurs. Here we show that, remarkably, it is the analytic branch of Sst(H ) which determines the large-deviation function Sf(H ) of the flat interface via a simple mapping Sf(H )=2-3 /2SstWhen fast and slow interfaces grow together: Connection to the half-space problem of the Kardar-Parisi-Zhang class

NASA Astrophysics Data System (ADS)

Ito, Yasufumi; Takeuchi, Kazumasa A.

2018-04-01

We study height fluctuations of interfaces in the (1 +1 ) -dimensional Kardar-Parisi-Zhang (KPZ) class, growing at different speeds in the left half and the right half of space. Carrying out simulations of the discrete polynuclear growth model with two different growth rates, combined with the standard setting for the droplet, flat, and stationary geometries, we find that the fluctuation properties at and near the boundary are described by the KPZ half-space problem developed in the theoretical literature. In particular, in the droplet case, the distribution at the boundary is given by the largest-eigenvalue distribution of random matrices in the Gaussian symplectic ensemble, often called the GSE Tracy-Widom distribution. We also characterize crossover from the full-space statistics to the half-space one, which arises when the difference between the two growth speeds is small.

A bilinear pairing based anonymous authentication scheme in wireless body area networks for mHealth.

PubMed

Jiang, Qi; Lian, Xinxin; Yang, Chao; Ma, Jianfeng; Tian, Youliang; Yang, Yuanyuan

2016-11-01

Wireless body area networks (WBANs) have become one of the key components of mobile health (mHealth) which provides 24/7 health monitoring service and greatly improves the quality and efficiency of healthcare. However, users' concern about the security and privacy of their health information has become one of the major obstacles that impede the wide adoption of WBANs. Anonymous and unlinkable authentication is critical to protect the security and privacy of sensitive physiological information in transit from the client to the application provider. We first show that the anonymous authentication scheme of Wang and Zhang based on bilinear pairing is prone to client impersonation attack. Then, we propose an enhanced anonymous authentication scheme to remedy the flaw in Wang and Zhang's scheme. We give the security analysis to demonstrate that the enhanced scheme achieves the desired security features and withstands various known attacks.

Recovering information of tunneling spectrum from weakly isolated horizon

NASA Astrophysics Data System (ADS)

Chen, Ge-Rui; Huang, Yong-Chang

2015-02-01

In this paper we investigate the properties of tunneling spectrum from weakly isolated horizon (WIH)—a locally defined black hole. We find that there exist correlations among Hawking radiations from a WIH, information can be carried out by such correlations, and the radiation is an entropy conservation process. Through revisiting the calculation of the tunneling spectrum from a WIH, we find that Zhang et al.'s (Ann Phys 326:350, 2011) requirement that radiated particles have the same angular momenta of a unit mass as that of the black hole is unnecessary, and the energy and angular momenta of the emitted particles are very arbitrary, restricted only by keeping the cosmic censorship hypothesis of black holes. So we resolve the information loss paradox based on the method of Zhang et al. (Phys Lett B 675:98, 2009; Ann Phys 326:350, 2011; Int J Mod Phys D 22:1341014, 2013) in a general case.

Temperature- and Bias-Dependence of Magnetoresistance in Doped Manganite Thin Film Trilayer Junctions

NASA Astrophysics Data System (ADS)

Sun, J. Z.; Xiao, Gang

1998-03-01

Large low-field magnetoresistance, up to a factor of five change in resistance, was observed in trilayer junctions formed by epitaxial thin films of La_0.67Sr_0.33 MnO3 - SrTiO3 - La_0.67Sr_0.33MnO3 at 4.2K and 100 Oe. Such magnetoresistance decreases with increasing sample temperature, and disappears for temperatures above 150K. The magnetoresistance also decreases upon increasing bias voltage across the junction. We present systematic experimental studies of both temperature and bias-dependence. These results in manganite trilayer junctions at low temperatures are similar to what has been observed in metallic trilayer magnetic tunneling valves, and are qualitatively consistent with the interface magnon excitation model proposed by Zhang et al.(S. Zhang, P. M. Levy, A. C. Marley and S. S. P. Parkin, Phys. Rev. Lett. 79), 3744 (1997).

Improved statistical fluctuation analysis for measurement-device-independent quantum key distribution with four-intensity decoy-state method.

PubMed

Mao, Chen-Chen; Zhou, Xing-Yu; Zhu, Jian-Rong; Zhang, Chun-Hui; Zhang, Chun-Mei; Wang, Qin

2018-05-14

Recently Zhang et al [ Phys. Rev. A95, 012333 (2017)] developed a new approach to estimate the failure probability for the decoy-state BB84 QKD system when taking finite-size key effect into account, which offers security comparable to Chernoff bound, while results in an improved key rate and transmission distance. Based on Zhang et al's work, now we extend this approach to the case of the measurement-device-independent quantum key distribution (MDI-QKD), and for the first time implement it onto the four-intensity decoy-state MDI-QKD system. Moreover, through utilizing joint constraints and collective error-estimation techniques, we can obviously increase the performance of practical MDI-QKD systems compared with either three- or four-intensity decoy-state MDI-QKD using Chernoff bound analysis, and achieve much higher level security compared with those applying Gaussian approximation analysis.

Generalized One-Band Model Based on Zhang-Rice Singlets for Tetragonal CuO

NASA Astrophysics Data System (ADS)

Hamad, I. J.; Manuel, L. O.; Aligia, A. A.

2018-04-01

Tetragonal CuO (T-CuO) has attracted attention because of its structure similar to that of the cuprates. It has been recently proposed as a compound whose study can give an end to the long debate about the proper microscopic modeling for cuprates. In this work, we rigorously derive an effective one-band generalized t -J model for T-CuO, based on orthogonalized Zhang-Rice singlets, and make an estimative calculation of its parameters, based on previous ab initio calculations. By means of the self-consistent Born approximation, we then evaluate the spectral function and the quasiparticle dispersion for a single hole doped in antiferromagnetically ordered half filled T-CuO. Our predictions show very good agreement with angle-resolved photoemission spectra and with theoretical multiband results. We conclude that a generalized t -J model remains the minimal Hamiltonian for a correct description of single-hole dynamics in cuprates.

An Efficient Remote Authentication Scheme for Wireless Body Area Network.

PubMed

Omala, Anyembe Andrew; Kibiwott, Kittur P; Li, Fagen

2017-02-01

Wireless body area network (WBAN) provide a mechanism of transmitting a persons physiological data to application providers e.g. hospital. Given the limited range of connectivity associated with WBAN, an intermediate portable device e.g. smartphone, placed within WBAN's connectivity, forwards the data to a remote server. This data, if not protected from an unauthorized access and modification may be lead to poor diagnosis. In order to ensure security and privacy between WBAN and a server at the application provider, several authentication schemes have been proposed. Recently, Wang and Zhang proposed an authentication scheme for WBAN using bilinear pairing. However, in their scheme, an application provider could easily impersonate a client. In order to overcome this weakness, we propose an efficient remote authentication scheme for WBAN. In terms of performance, our scheme can not only provide a malicious insider security, but also reduce running time of WBAN (client) by 51 % as compared to Wang and Zhang scheme.

The beam diagnostic instruments in Beijing radioactive ion-beam facilities isotope separator on-line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, Y., E-mail: yjma@ciae.ac.cn; Cui, B.; Ma, R.

The beam diagnostic instruments for Beijing Radioactive Ion-beam Facilities Isotope Separator On-Line are introduced [B. Q. Cui, Z. H. Peng, Y. J. Ma, R. G. Ma, B. Tang, T. Zhang, and W. S. Jiang, Nucl. Instrum. Methods 266, 4113 (2008); T. J. Zhang, X. L. Guan, and B. Q. Cui, in Proceedings of APAC 2004, Gyeongju, Korea, 2004, http://www.jacow.org , p. 267]. For low intensity ion beam [30–300 keV/1 pA–10 μA], the beam profile monitor, the emittance measurement unit, and the analyzing slit will be installed. For the primary proton beam [100 MeV/200 μA], the beam profile scanner will bemore » installed. For identification of the nuclide, a beam identification unit will be installed. The details of prototype of the beam diagnostic units and some experiment results will be described in this article.« less

Infrared conductivity of cuprates using Yang-Rice-Zhang ansatz: Review of our recent investigations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Navinder; Sharma, Raman

2015-05-15

A review of our recent investigations related to the ac transport properties in the psedogapped state of cuprate high temperature superconductors is presented. For our theoretical calculations we use a phenomenological Green’s function proposed by Yang, Rice and Zhang (YRZ). This is based upon the renormalized mean-field theory of the Hubbard model and takes into account the strong electron-electron interaction present in Cuprates. The pseudogap is also taken into account through a proposed self energy. We have tested the form of the Green’s function by computing ac conductivity of cuprates and then compared with experimental results. We found agreement betweenmore » theory and experiment in reproducing the doping evolution of ac conductivity but there is a problem with absolute magnitudes and their frequency dependence. This shows a partial success of the YRZ ansatz. The ways to rectify it are suggested and worked out.« less

Towards a footwear design tool: influence of shoe midsole properties and ground stiffness on the impact force during running.

PubMed

Ly, Quoc Hung; Alaoui, Amina; Erlicher, Silvano; Baly, Laurent

2010-01-19

Several spring-damper-mass models of the human body have been developed in order to reproduce the measured ground vertical reaction forces during human running (McMahon and Cheng, 1990; Ferris et al., 1999; Liu and Nigg, 2000). In particular, Liu and Nigg introduced at the lower level of their model, i.e. at the interface between the human body and the ground, a nonlinear element representing simultaneously the shoe midsoles and the ground flexibility. The ground reaction force is modelled as the force supported by this nonlinear element, whose parameters are identified from several sets of experimental data. This approach proved to be robust and quite accurate. However, it does not explicitly take into account the shoe and the ground properties. It turns out to be impossible to study the influence of shoe materials on the impact force, for instance for footwear design purposes. In this paper, a modification of the Liu and Nigg's model is suggested, where the original nonlinear element is replaced with a bi-layered spring-damper-mass model: the first layer represents the shoe midsole and the second layer is associated with the ground. Ground is modelled as an infinite elastic half-space. We have assumed a viscoelastic behaviour of the shoe material, so the damping of shoe material is taken into account. A methodology for the shoe-soles characterization is proposed and used together with the proposed model. A parametric study is then conducted and the influence of the shoe properties on the impact force is quantified. Moreover, it is shown that impact forces are strongly affected by the ground stiffness, which should therefore be considered as an essential parameter in the footwear design. Copyright 2009 Elsevier Ltd. All rights reserved.

Magnetic Viruses: Utilizing Self-Assembly for Biomedical Applications

NASA Astrophysics Data System (ADS)

Hoffmann, Axel

2006-03-01

Magnetic nanoparticles coated with biochemical surfactants have emerged recently as an important component for enabling many biological and medical applications. We implemented a biotemplating approach to create such magnetic nanoparticles by utilizing native protein capsid shells derived in high yield from the T7 bacteriophage virus. The magnetic nanoparticles are grown via bio-mineralization reactions inside of hollowed-out capsids that retain their original chemical recognition properties. The resultant ``magnetic viruses'' are uniform in geometry, physical properties, and biochemical functionality. This makes these viruses ideally suited for many biomedical applications among which we investigated specifically a novel sensing scheme for target recognition based on Brownian relaxation. For this scheme we use the ac-susceptibility of the functionalized magnetic nanoparticles suspended in liquid. Upon binding the target of interest to the particles, their Brownian relaxation time is modified, which is readily detected by a change of the frequency dependence of the magnetic susceptibility. This scheme has several advantages; (i) it requires only one binding event for sensing; (ii) there is a useful signal both in the absence and presence of the target; (iii) the signal contains information about the size of the target besides the biochemical affinity; and (iv) since the binding modifies the magnetic susceptibility of the magnetic particles there is no need for removing unbound labels. C. Liu, S.-H. Chung, Q. Jin, A. Sutton, F. Yan, B. K. Kay, S. D. Bader, L. Makowski, and L. Chen, J. Magn. Magn. Mater, in press. S.H. Chung, A. Hoffmann, S. D. Bader, C. Liu, B. Kay, L. Makowski, and L. Chen, Appl. Phys. Lett. 85, 2971 (2004) ; S. H. Chung, A. Hoffmann, K. Guslienko, S. D. Bader, C. Liu, B. Kay, L. Makowski, and L. Chen, J. Appl. Phys. 97, 10R101 (2005).

Low-intensity ultrasound adjuvant therapy: enhancement of doxorubicin-induced cytotoxicity and the acoustic mechanisms involved.

PubMed

Kondo, Takashi; Yoshida, Toru; Ogawa, Ryohei; Hassan, Mariame A; Furusawa, Yukihiro; Zhao, Qing-Li; Watanabe, Akihiko; Morii, Akihiro; Feril, Loreto B; Tachibana, Katsuro; Kitagawa, Hiroshi; Tabuchi, Yoshiaki; Takasaki, Ichiro; Shehata, Mohammad H; Kudo, Nobuki; Tsukada, Kazuhiro

2009-06-01

In this study, the effects of low-intensity pulsed ultrasound (LIU) as an adjuvant to doxorubicin (DOX) treatment was further investigated in comparison to hyperthermia as another widely used adjuvant. The effects were compared with respect to cell killing and apoptosis induction in U937 cells. Human primary liver cancer (PLC) cells were also used to evaluate the effects of the combinations. The use of an echo contrast agent was investigated for further enhancement of cytotoxicity. Finally, the acoustic mechanisms involved were investigated. The effects of different treatment regimens on cell viability were determined using the Trypan blue dye-exclusion test. Apoptosis induction was detected by flow cytometry using fluorescein isothiocyanate-annexin V and propidium iodide staining. The mechanistic study involved electron paramagnetic spin trapping for detecting free radical formation as an indicator of the occurrence of inertial cavitation and spectrophotometry for sucrose hydrolysis as an indicator for noncavitational effects. The combination treatments exerted synergistic effects on cytotoxicity depending on the acoustic conditions used. The use of LIU as an adjuvant to DOX treatment was shown to be superior to the use of hyperthermia as an adjuvant. Moreover, the combination seems to be promising for other cancer types provided that the acoustic conditions are properly selected with respect to drug concentration. The key ultrasound mechanism responsible for the synergism observed was shown to be the production of free radicals by inertial cavitation. Non-cavitational forces were also shown to contribute to the effect. This study is motivating to engage in in vivo research with various cancer types as a step toward clinical applicability and is emphasizing on the importance of developing therapeutic protocols for setting LIU parameters with respect to other therapeutic conditions.

Assessment of Template-Based Modeling of Protein Structure in CASP11

PubMed Central

Modi, Vivek; Xu, Qifang; Adhikari, Sam; Dunbrack, Roland L.

2016-01-01

We present the assessment of predictions submitted in the template-based modeling (TBM) category of CASP11 (Critical Assessment of Protein Structure Prediction). Model quality was judged on the basis of global and local measures of accuracy on all atoms including side chains. The top groups on 39 human-server targets based on model 1 predictions were LEER, Zhang, LEE, MULTICOM, and Zhang-Server. The top groups on 81 targets by server groups based on model 1 predictions were Zhang-Server, nns, BAKER-ROSETTASERVER, QUARK, and myprotein-me. In CASP11, the best models for most targets were equal to or better than the best template available in the Protein Data Bank, even for targets with poor templates. The overall performance in CASP11 is similar to the performance of predictors in CASP10 with slightly better performance on the hardest targets. For most targets, assessment measures exhibited bimodal probability density distributions. Multi-dimensional scaling of an RMSD matrix for each target typically revealed a single cluster with models similar to the target structure, with a mode in the GDT-TS density between 40 and 90, and a wide distribution of models highly divergent from each other and from the experimental structure, with density mode at a GDT-TS value of ~20. The models in this peak in the density were either compact models with entirely the wrong fold, or highly non-compact models. The results argue for a density-driven approach in future CASP TBM assessments that accounts for the bimodal nature of these distributions instead of Z-scores, which assume a unimodal, Gaussian distribution. PMID:27081927

Relativistic distorted-wave collision strengths for the 49 Δn=0 optically allowed transitions with n=2 in the 67 N-like ions with 26≤Z≤92

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fontes, Christopher J., E-mail: cjf@lanl.gov; Zhang, Hong Lin

2014-09-15

Relativistic distorted-wave collision strengths have been calculated for the 49 Δn=0 optically allowed transitions with n=2 in the 67 N-like ions with nuclear charge number Z in the range 26≤Z≤92. The calculations were made for the four final, or scattered, electron energies E{sup ′}=0.20, 0.42, 0.80, and 1.40, where E{sup ′} is in units of Z{sub eff}{sup 2} Ry with Z{sub eff}=Z−5. In the present calculations, an improved “top-up” method, which employs relativistic plane waves, was used to obtain the high partial-wave contribution for each transition, in contrast to the partial-relativistic Coulomb–Bethe approximation used in the previous work by Zhangmore » and Sampson [H.L. Zhang and D.H. Sampson, At. Data Nucl. Data Tables 72 (1999) 153]. In that earlier work, collision strengths were also provided for N-like ions, but for a more comprehensive data set consisting of all possible 105 Δn=0 transitions, six scattered energies and the 81 ions with Z in the range 12≤Z≤92. The collision strengths covered in the present work should be more accurate than the corresponding data given by Zhang and Sampson [H.L. Zhang and D.H. Sampson, At. Data Nucl. Data Tables 72 (1999) 153] and are presented here to replace those earlier results.« less

Radiation Environment at GEO from the FY2G Satellite Observations

NASA Astrophysics Data System (ADS)

Wang, C.

2016-12-01

WANG Chun-Qin1,2*, Zhang Shen-Yi1,2 Jing Tao1,2, Zhang Huan-Xin1,2 Li Jia-Wei3 Zhang Xiao-Xin3 Sun Yue-Qiang1,2 Liang Jin-Bao1,2 Wei Fei1,2 Shen Guo-Hong1,2 Huang Cong3 Shi Chun-Yan1,21.National Space Science Center, Chinese Academy of Sciences, Beijing 100190, China; 2.Beijing Key Laboratory of Space Environment Exploration, Beijing 100190,China 3.National Satellite Meteorological Center, National Center for Space Weather, Beijing 100081, China; Abstract Recent measurements of the high energy electrons and protons with energetic particle instrument carried on the FY-2G satellite are presented. The instrument consist of two detectors-the high energy electrons instrument which can measure 200keV to greater than 4MeV electrons with eleven channels, and the high energy protons and heavy ions instrument which mainly senses incident flux of solar protons with seven channels from 4MeV to 300 MeV. The paper shows electrons and protons observations from Jan 2015 until Oct 2015. A precise description and preliminary analysis of particle dynamic during disturbances of magnetic storms、substorms and solar eruptions suggest that both of the detectors show accurate response to various disturbances and provide refined particles data. Comparison results of FY2G satellite with GOES series satellites reflect obvious local difference in particle flux evolvement especially during intensive disturbances time, which can be helpful for data assimilation of multi-satellite as well as further research in more complicated magnetosphere energy particle dynamic.

Zfp206 regulates ES cell gene expression and differentiation.

PubMed

Zhang, Wen; Walker, Emily; Tamplin, Owen J; Rossant, Janet; Stanford, William L; Hughes, Timothy R

2006-01-01

Understanding transcriptional regulation in early developmental stages is fundamental to understanding mammalian development and embryonic stem (ES) cell properties. Expression surveys suggest that the putative SCAN-Zinc finger transcription factor Zfp206 is expressed specifically in ES cells [Zhang,W., Morris,Q.D., Chang,R., Shai,O., Bakowski,M.A., Mitsakakis,N., Mohammad,N., Robinson,M.D., Zirngibl,R., Somogyi,E. et al., (2004) J. Biol., 3, 21; Brandenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K. et al., (2004) Nat. Biotechnol., 22, 707-716]. Here, we confirm this observation, and we show that ZFP206 expression decreases rapidly upon differentiation of cultured mouse ES cells, and during development of mouse embryos. We find that there are at least six isoforms of the ZFP206 transcript, the longest being predominant. Overexpression and depletion experiments show that Zfp206 promotes formation of undifferentiated ES cell clones, and positively regulates abundance of a very small set of transcripts whose expression is also specific to ES cells and the two- to four-cell stages of preimplantation embryos. This set includes members of the Zscan4, Thoc4, Tcstv1 and eIF-1A gene families, none of which have been functionally characterized in vivo but whose members include apparent transcription factors, RNA-binding proteins and translation factors. Together, these data indicate that Zfp206 is a regulator of ES cell differentiation that controls a set of genes expressed very early in development, most of which themselves appear to be regulators.

Corrigendum to ;Power-law distributed temporal heterogeneity of human activities promotes cooperation on complex networks; [Physica A 457 (2016) 93-100

NASA Astrophysics Data System (ADS)

Liu, Chao; Li, Rong

2017-06-01

The authors regret that the address of the author Chao Liu has been published incorrectly. It should read as: School of Mathematics, Shanghai University of Finance and Economics, Shanghai 200433, China.

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Chemical and Mechanical Properties of Surfaces, Interfaces and Nanostructures Inorganic-Organic (2016). top Inorganic-Organic Nanocomposites Program Leader: Ting Xu Co-PI's: A. Paul Alivisatos, Yi Liu , Miquel Salmeron, Lin-Wang Wang The organic/inorganic nanocomposite program aims to design and synthesize

Asynchronous Discussions in Online Multicultural Education

ERIC Educational Resources Information Center

Licona, Miguel M.; Gurung, Binod

2011-01-01

With the proliferation of technological innovations, especially information and communication technologies, there is a rapidly increasing trend for universities to offer online courses (Tallent-Runnels, Thomas, Lan, Cooper, Ahern, Shaw, & Liu, 2006). Rationalized within the premises of cost and time efficiency, online education promises a new mode…

Kinetics Modeling of Hypergolic Propellants

DTIC Science & Technology

2013-07-01

comprehensive preconditioning and employs the line Gauss Seidel algorithm for the solution of the linear system. A multi-block unstructured mesh is...Explosives, Pyrotechnics, 33(3):209–212, 2008. 24Wei-Guang Liu, Shiqing Wang, Siddharth Dasgupta, Stefan T Thynell, William A Goddard III, Sergey Zybin

COMMITTEES: SQM2008-International Conference on Strangeness in Quark Matter SQM2008-International Conference on Strangeness in Quark Matter

NASA Astrophysics Data System (ADS)

2008-04-01

Local Organising Committee Xiangzhou Cai (SINPA) Weiqin Chao (CCAST) Liewen Chen (SJTU) Jianping Cheng (Tsinghua University) Jinghua Fu (CCNU) Yuanning Gao (Tsinghua University) Xiaomei Li (CIAE) Zuotang Liang (Shandong University) Feng Liu (CCNU), Co-chair Yuxin Liu (PKU) Qing Wang (Tsinghua University) Qun Wang (USTC) Hushan Xu (IMP) Daicui Zhou (CCNU) Pengfei Zhuang (Tsinghua University), Co-chair Bingsong Zou (IHEP) International Advisory Committee Jörg Aichelin, Nantes Federico Antinori, Padova Tamás Biró, Budapest Peter Braun-Munzinger, GSI Jean Cleymans, Cape Town László Csernai, Bergen Timothy Hallman, BNL Huan Zhong Huang, UCLA Takeshi Kodama, Rio de Janeiro Carlos Lourenço, CERN Yu-Gang Ma, Shanghai Jes Masden, Aarhus Yasuo Miake, Tsukuba Berndt Müller, Duke Grazyna Odyniec, LBNL Helmut Oeschler, Darmstadt Johann Rafelski, Arizona Hans Georg Ritter, LBNL Karel Šafařík, CERN Jack Sandweiss, Yale George S F Stephans, MIT Horst Stöcker, Frankfurt Thomas Ullrich, BNL Nu Xu, LBNL William A Zajc, Columbia

Brillouin Scattering of Picosecond Laser Pulses in Preformed, Short-Scale-Length Plasmas

NASA Astrophysics Data System (ADS)

Gaeris, A. C.; Fisher, Y.; Delettrez, J. A.; Meyerhofer, D. D.

1996-11-01

Brillouin scattering (BS) has been studied in short-scale-length, preformed plasmas. The backscattered and specularly reflected light resulting from the interaction of high-power picosecond pulses with preformed silicon plasmas has been measured. A first laser pulse forms a short-scale-length plasma -- without significant BS -- while a second delayed pulse interacts with an expanded, drifting underdense region of the plasma with density scale length (0 <= Ln <= 600 λ _L). The pulses are generated at λ L = 1054 nm, with intensities up to 10^16 W/cm^2. The backscattered light spectra, threshold intensities, and enhanced reflectivities have been determined for different plasma-density scale lengths and are compared to Liu, Rosenbluth, and White's(C. S. Liu, M. N. Rosenbluth, and R. B. White, Phys. Fluids 17, 1211 (1974).) WKB treatment of stimulated Brillouin scattering in inhomogeneous drifting plasmas. This work was supported by the U.S. Department of Energy Office of Inertial Confinement Fusion under Cooperative Agreement No. DE-FC03-92SF19460.

On the interpretation of complex network analysis of language. Comment on "Approaching human language with complex networks" by Jin Cong, Haitao Liu

NASA Astrophysics Data System (ADS)

Čech, Radek

2014-12-01

After a rapid and successful development of the theory of complex networks at the turn of the millennium [1,2], attempts to apply this theory to a language analysis emerged immediately [3,4]. The first results seemed to bring new insights to the functioning of language. Moreover, some authors assumed that this approach can even solve some fundamental problems concerning language evolution [5,6]. However, after a decade of the application of complex network theory to language analysis, the initial expectations have not been fulfilled, in my opinion, and the need for a deeper, linguistically based explanation of observed properties has been still more obvious. Cong and Liu's review [7] can be seen as a successful attempt to clarify the main aspects of this kind of research from the linguistics point of view. However, I see two problematic aspects in their study relating to the nature of the character of explanation.

Computer simulation as an important approach to explore language universal. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Lu, Qian

2017-07-01

Exploring language universal is one of the major goals of linguistic researches, which are largely devoted to answering the ;Platonic questions; in linguistics, that is, what is the language knowledge, how to get and use this knowledge. However, if solely guided by linguistic intuition, it is very difficult for syntactic studies to answer these questions, or to achieve abstractions in the scientific sense. This suggests that linguistic analyses based on the probability theory may provide effective ways to investigate into language universals in terms of biological motivations or cognitive psychological mechanisms. With the view that ;Language is a human-driven system;, Liu, Xu & Liang's review [1] pointed out that dependency distance minimization (DDM), which has been corroborated by big data analysis of corpus, may be a language universal shaped in language evolution, a universal that has profound effect on syntactic patterns.

First-principles studies of the v7×v7R19.1° structure of sulfur on the Pd(1 1 1) surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alfonso, D.R.

2007-11-01

Density functional theory is used to investigate the v7×v7R19.1° structure of sulfur on the Pd(111) surface. Among the different models that were considered, the densely packed mixed sulfur-metal overlayer structure proposed by Liu et al. [W. Liu, K.A.R. Mitchell, W. Berndt, Surf. Sci. 393 (1997) L119] was found to be the most energetically favorable. This model consists of arrangement of Pd triangles and pentagons on top of Pd(111) with the sulfur atoms at 3/7 monolayer coverage. The dominant mechanism for sulfur interaction with Pd in the overlayer region is the rehybridization of sulfur 3p and metal 4d bands. Simulated scanningmore » tunneling microscopy image for this structure shows some similarity with that obtained from experiment. Our study confirms that surface sulfide with no structural resemblance to its bulk counterparts can form on Pd(111).« less

Collaborators | Center for Cancer Research

Cancer.gov

Collaborators Structural Biophysics Laboratory, CCR Macromolecular NMR Section (R. Andrew Byrd, Ph.D.) Protein-Nucleic Acid Interactions Section (Yun-Xing Wang, Ph.D.) Protein Processing Section (Kylie J. Walters, Ph.D.) Kinase Complexes Section (Ping Zhang, Ph.D.) Macromolecular Crystallography Laboratory, CCR

Validation of Biomarkers for Prostate Cancer Prognosis

DTIC Science & Technology

2013-10-01

prostate cancer research community for testing candidate biomarkers. Groups using the resource include Dr. Jeremy Squire, Dr. Gustavo Ayala, and Dr...Ferrari, Javier Hernandez , Antonio Hurtado-Coll, Kyle Kuchinsky, Janet Liew, Rosario Mendez-Meza, Elizabeth Smith, Imelda Tenggarra, Xiaotun Zhang

Uncertainty in regional and zonal monthly mean downward surface irradiances from Edition 4.0 CERES Energy Balanced and Filled (EBAF) data product

NASA Astrophysics Data System (ADS)

Kato, S.; Rutan, D. A.; Rose, F. G.; Loeb, N. G.

2017-12-01

The surface of the Earth receives solar radiation (shortwave) and emission from the atmosphere (longwave). At a global and annual mean approximately 12% of solar radiation incident on the surface is reflected and the rest is absorbed by the surface. The surface emits radiation proportional to the forth power of the temperature. Although the uncertainty in global and annual mean surface irradiances is estimated in earlier studies (Zhang et al. 1995, 2004; L'Ecuyer et al. 2008; Stephens et al. 2012; Kato et al. 2012), only a few studies estimated the uncertainty in computed surface irradiances at smaller spatial and temporal scales (Zhang et al. 1995, 2004; Kato et al. 2012). We use surface observations at 46 buoys and 36 land sites and newly released the Edition 4.0 Clouds and the Earth's Radiant Energy System (CERES) Energy Balanced and Filled (EBAF)-surface data product to estimate the uncertainty in regional and zonal monthly mean downward shortwave and longwave surface irradiances. The root-mean-square difference of monthly mean computed and observed irradiances is used for the regional uncertainty. The uncertainty is separated into bias and spatially random components. The random component decreases when irradiances are averaged over a larger area, nearly inversely proportional to the number of surface observation sites. The presentation provides the uncertainty in the regional and zonal monthly mean downward surface irradiances over ocean and land. ReferencesKato, S. and N.G.Loeb, D. A.Rutan, F. G. Rose, S. Sun-Mack,W.F.Miller, and Y. Chen, 2012. Surv. Geophys., 33, 395-412, doi:10.1007/s10712-012-9179-x. L'Ecuyer, T. S., N. B. Wood, T. Haladay, G. L. Stephens, and P. W. Stackhouse Jr., 2008, J. Geophys. Res., 113, D00A15, doi:10.1029/2008JD009951. Stephens, G. L. and Coauthors, 2012, Nat. Geosci., 5, 691-696, doi:10.1038/ngeo1580. Zhang, Y., W. B. Rossow, A. A. Lacis, V. Oinas, and M. I. Mishchenko, 2004, J. Geophys. Res., 109, D19105, doi:10.1029/2003JD004457. Zhang, Y.-C., W. B. Rossow, and A. A. Lacis, 1995, J. Geophys. Res., 100, 1149-1165.

Evaluation of five dry particle deposition parameterizations for incorporation into atmospheric transport models

NASA Astrophysics Data System (ADS)

Khan, Tanvir R.; Perlinger, Judith A.

2017-10-01

Despite considerable effort to develop mechanistic dry particle deposition parameterizations for atmospheric transport models, current knowledge has been inadequate to propose quantitative measures of the relative performance of available parameterizations. In this study, we evaluated the performance of five dry particle deposition parameterizations developed by Zhang et al. (2001) (Z01), Petroff and Zhang (2010) (PZ10), Kouznetsov and Sofiev (2012) (KS12), Zhang and He (2014) (ZH14), and Zhang and Shao (2014) (ZS14), respectively. The evaluation was performed in three dimensions: model ability to reproduce observed deposition velocities, Vd (accuracy); the influence of imprecision in input parameter values on the modeled Vd (uncertainty); and identification of the most influential parameter(s) (sensitivity). The accuracy of the modeled Vd was evaluated using observations obtained from five land use categories (LUCs): grass, coniferous and deciduous forests, natural water, and ice/snow. To ascertain the uncertainty in modeled Vd, and quantify the influence of imprecision in key model input parameters, a Monte Carlo uncertainty analysis was performed. The Sobol' sensitivity analysis was conducted with the objective to determine the parameter ranking from the most to the least influential. Comparing the normalized mean bias factors (indicators of accuracy), we find that the ZH14 parameterization is the most accurate for all LUCs except for coniferous forest, for which it is second most accurate. From Monte Carlo simulations, the estimated mean normalized uncertainties in the modeled Vd obtained for seven particle sizes (ranging from 0.005 to 2.5 µm) for the five LUCs are 17, 12, 13, 16, and 27 % for the Z01, PZ10, KS12, ZH14, and ZS14 parameterizations, respectively. From the Sobol' sensitivity results, we suggest that the parameter rankings vary by particle size and LUC for a given parameterization. Overall, for dp = 0.001 to 1.0 µm, friction velocity was one of the three most influential parameters in all parameterizations. For giant particles (dp = 10 µm), relative humidity was the most influential parameter. Because it is the least complex of the five parameterizations, and it has the greatest accuracy and least uncertainty, we propose that the ZH14 parameterization is currently superior for incorporation into atmospheric transport models.

Expression, purification, and characterization of human acetyl-CoA carboxylase 2.

PubMed

Kim, Ki Won; Yamane, Harvey; Zondlo, James; Busby, James; Wang, Minghan

2007-05-01

The full-length human acetyl-CoA carboxylase 1 (ACC1) was expressed and purified to homogeneity by two separate groups (Y.G. Gu, M. Weitzberg, R.F. Clark, X. Xu, Q. Li, T. Zhang, T.M. Hansen, G. Liu, Z. Xin, X. Wang, T. McNally, H. Camp, B.A. Beutel, H.I. Sham, Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors, J. Med. Chem. 49 (2006) 3770-3773; D. Cheng, C.H. Chu, L. Chen, J.N. Feder, G.A. Mintier, Y. Wu, J.W. Cook, M.R. Harpel, G.A. Locke, Y. An, J.K. Tamura, Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes, Protein Expr. Purif., in press). However, neither group was successful in expressing the full-length ACC2 due to issues of solubility and expression levels. The two versions of recombinant human ACC2 in these reports are either truncated (lacking 1-148 aa) or have the N-terminal 275 aa replaced with the corresponding ACC1 region (1-133 aa). Despite the fact that ACC activity was observed in both cases, these constructs are not ideal because the N-terminal region of ACC2 could be important for the correct folding of the catalytic domains. Here, we report the high level expression and purification of full-length human ACC2 that lacks only the N-terminal membrane attachment sequence (1-20 and 1-26 aa, respectively) in Trichoplusia ni cells. In addition, we developed a sensitive HPLC assay to analyze the kinetic parameters of the recombinant enzyme. The recombinant enzyme is a soluble protein and has a K(m) value of 2 microM for acetyl-CoA, almost 30-fold lower than that reported for the truncated human ACC2. Our recombinant enzyme also has a lower K(m) value for ATP (K(m)=52 microM). Although this difference could be ascribed to different assay conditions, our data suggest that the longer human ACC2 produced in our system may have higher affinities for the substrates and could be more similar to the native enzyme.

Integrated underground gas storage of CO2 and CH4 for renewable energy storage for a test case in China

NASA Astrophysics Data System (ADS)

Kühn, Michael; Li, Qi; Nakaten, Natalie, Christine; Kempka, Thomas

2017-04-01

Integration and further development of the energy supply system in China is a major challenge for the years to come. Part of the strategy is the implementation of a low carbon energy system based on carbon dioxide capture and storage (CCS). The innovative idea presented here is based on an extension of the power-to-gas-to-power (PGP) technology by establishing a closed carbon dioxide cycle [1]. Thereto, hydrogen generated from excess renewable energy is transformed into methane for combustion in a combined cycle gas power plant. To comply with the fluctuating energy demand, carbon dioxide produced during methane combustion and required for the methanation process as well as excess methane are temporarily stored in two underground reservoirs located close to each other [2]. Consequently, renewable energy generation units can be operated even if energy demand is below consumption, while stored energy can be fed into the grid as energy demand exceeds production [3]. We studied a show case for Xinjiang in China [4] to determine the energy demand of the entire process chain based on numerical computer simulations for the operation of the CO2 and CH4 storage reservoirs, and to ascertain the pressure regimes present in the storage formations during the injection and production phases of the annual cycle. [1] Streibel M., Nakaten N., Kempka T., Kühn M. (2013) Analysis of an integrated carbon cycle for storage of renewables. Energy Procedia 40, 202-211. doi: 10.1016/j.egypro.2013.08.024. [2] Kühn M., Streibel M., Nakaten N.C., Kempka T. (2014) Integrated Underground Gas Storage of CO2 and CH4 to Decarbonise the "Power-to-gas-to-gas-to-power" Technology. Energy Procedia 59, 9-15. doi: 10.1016/j.egypro.2014.10.342 [3] Kühn M., Nakaten N.C., Streibel M., Kempka T. (2014) CO2 Geological Storage and Utilization for a Carbon Neutral "Power-to-gas-to-power" Cycle to Even Out Fluctuations of Renewable Energy Provision. Energy Procedia 63, 8044-8049. doi: 10.1016/j.egypro.2014.11.841 [4] Li Q., Chen Z.A., Zhang J.T., Liu L.C., Li X.C., Jia L. (2016) Positioning and Revision of CCUS Technology Development in China. International Journal of Greenhouse Gas Control 46, 282-293. doi: 10.1016/j.ijggc.2015.02.024

[The Seongho () School's Study of the Ancient Learning () and Its Influence on the Debate about Materia Medica in the Late Joseon Dynasty].

PubMed

Cho, Sung-San

2015-08-01

This study will determine the ways in which the ancient learning (gu xue, ) scholarship of the Seongho School, and its interest in the materia medica (ben cao xue, ) were related during the late Joseon period. The Seongho School centered its studies mainly on classical Chinese texts of the Han (206 BC－AD 220) and pre-Han (?－221 BC) (xian-qin lianghan, ) periods rather than those of the Tang and Song dynasties (618-1279). gu xue scholarship emerged during the Ming dynasty era (1368 －1644) as an alternative to the scholarly trends of the Song dynasty, which were dependent on Zhu Xi's (, 1130－1200) Neo-Confucianism and its interpretation of Han and pre-Han classical Chinese texts. This scholarly trend influenced Korean and Japanese literature, philosophy, and even medicine from the seventeenth through the nineteenth centuries. Focusing on Korean scholarship, we find a great deal of research regarding the influence of gu xue on Korean classical Chinese literature and Confucian philosophy in the late Joseon period; however, no study has examined how this style of scholarship influenced the field of medicine during the same period. This study will investigate how the intellectuals of the Seongho School, who did the most to develop gu xue among Joseon intellectuals, were influenced by this style of scholarship in their study of the materia medica. Jeong Yak-yong (1762－1836), the representative intellectual of the Seongho School, did not focus on complicated metaphysical medical theories, such as the Yin-Yang and Five Elements theory (yin yang wu xing shui, ) or the Five Movements and Six Atmospheres theory (wu yun liu qi shui, ). Instead, his interests lay in the exact diagnoses of diseases and meticulous herbal prescriptions which formed an essential part of the Treatise on Exogenous Febrile Disease (Shang han lun, ) written by Zhang Zhungjing (, 150－219) in the Han dynasty. The Treatise was compatible with the scholarly purpose of gu xue in that they both eschewed metaphysical explanations. The Seongho School's interest in the materia medica stemmed from a desire to improve the delivery and quality of medical practices in rural communities, where metaphysical theories of medicine did not prevail and the cost of medicine was prohibitive.

Calibration of soil moisture flow simulation models aided by the active heated fiber optic distributed temperature sensing AHFO

NASA Astrophysics Data System (ADS)

Rodriguez-Sinobas, Leonor; Zubelzu, Sergio; Sobrino, Fernando Fernando; Sánchez, Raúl

2017-04-01

Most of the studies dealing with the development of water flow simulation models in soils, are calibrated using experimental data measured by soil probe sensors or tensiometers which locate at specific points in the study area. However since the beginning of the XXI century, the use of Distributed Fiber Optic Temperature Measurement for estimating temperature variation along a cable of fiber optic has been assessed in multiple environmental applications. Recently, its application combined with an active heating pulses technique (AHFO) has been reported as a sensor to estimate soil moisture. This method applies a known amount of heat to the soil and monitors the temperature evolution, which mainly depends on the soil moisture content. Thus, it allows estimations of soil water content every 12.5 cm along the fiber optic cable, as long as 1500 m , with 2 % accuracy , every second. This study presents the calibration of a soil water flow model (developed in Hydrus 2D) with the AHFO technique. The model predicts the distribution of soil water content of a green area irrigated by sprinkler irrigation. Several irrigation events have been evaluated in a green area located at the ETSI Agronómica, Agroalimentaria y Biosistemas in Madrid where an installation of 147 m of fiber optic cable at 15 cm depth is deployed. The Distribute Temperature Sensing unit was a SILIXA ULTIMA SR (Silixa Ltd, UK) and has spatial and temporal resolution of 0.29 m. Data logged in the DTS unit before, during and after the irrigation event were used to calibrate the estimations in the Hydrus 2D model during the infiltration and redistribution of soil water content within the irrigation interval. References: Karandish, F., & Šimůnek, J. (2016). A field-modeling study for assessing temporal variations of soil-water-crop interactions under water-saving irrigation strategies. Agricultural Water Management, 178, 291-303. Li, Y., Šimůnek, J., Jing, L., Zhang, Z., & Ni, L. (2014). Evaluation of water movement and water losses in a direct-seeded-rice field experiment using Hydrus-1D. Agricultural Water Management, 142, 38-46. Tan, X., Shao, D., & Liu, H. (2014). Simulating soil water regime in lowland paddy fields under different water managements using HYDRUS-1D. Agricultural Water Management, 132, 69-78.

NEU1 Sialidase Regulates the Sialylation State of CD31 and Disrupts CD31-driven Capillary-like Tube Formation in Human Lung Microvascular Endothelia*

PubMed Central

Lee, Chunsik; Liu, Anguo; Miranda-Ribera, Alba; Hyun, Sang Won; Lillehoj, Erik P.; Cross, Alan S.; Passaniti, Antonino; Grimm, P. Richard; Kim, Bo-Young; Welling, Paul A.; Madri, Joseph A.; DeLisser, Horace M.; Goldblum, Simeon E.

2014-01-01

The highly sialylated vascular endothelial surface undergoes changes in sialylation upon adopting the migratory/angiogenic phenotype. We recently established endothelial cell (EC) expression of NEU1 sialidase (Cross, A. S., Hyun, S. W., Miranda-Ribera, A., Feng, C., Liu, A., Nguyen, C., Zhang, L., Luzina, I. G., Atamas, S. P., Twaddell, W. S., Guang, W., Lillehoj, E. P., Puché, A. C., Huang, W., Wang, L. X., Passaniti, A., and Goldblum, S. E. (2012) NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia. NEU1 restrains endothelial cell migration whereas NEU3 does not. J. Biol. Chem. 287, 15966–15980). We asked whether NEU1 might regulate EC capillary-like tube formation on a Matrigel substrate. In human pulmonary microvascular ECs (HPMECs), prior silencing of NEU1 did not alter tube formation. Infection of HPMECs with increasing multiplicities of infection of an adenovirus encoding for catalytically active WT NEU1 dose-dependently impaired tube formation, whereas overexpression of either a catalytically dead NEU1 mutant, NEU1-G68V, or another human sialidase, NEU3, did not. NEU1 overexpression also diminished EC adhesion to the Matrigel substrate and restrained EC migration in a wounding assay. In HPMECs, the adhesion molecule, CD31, also known as platelet endothelial cell adhesion molecule-1, was sialylated via α2,6-linkages, as shown by Sambucus nigra agglutinin lectin blotting. NEU1 overexpression increased CD31 binding to Arachis hypogaea or peanut agglutinin lectin, indicating CD31 desialylation. In the postconfluent state, when CD31 ectodomains are homophilically engaged, NEU1 was recruited to and desialylated CD31. In postconfluent ECs, CD31 was desialylated compared with subconfluent cells, and prior NEU1 silencing completely protected against CD31 desialylation. Prior CD31 silencing and the use of CD31-null ECs each abrogated the NEU1 inhibitory effect on EC tube formation. Sialyltransferase 6 GAL-I overexpression increased α2,6-linked CD31 sialylation and dose-dependently counteracted NEU1-mediated inhibition of EC tube formation. These combined data indicate that catalytically active NEU1 inhibits in vitro angiogenesis through desialylation of its substrate, CD31. PMID:24550400

Changing Workplace.

ERIC Educational Resources Information Center

1998

This document contains four papers from a symposium on the changing workplace and its relationship to human resource development (HRD). In "Globalization, Immigration and Quality of Life Dynamics for Reverse Brain Drains" (Ben-Chieh Liu, Maw Lin Lee, Hau-Lien), the factors responsible for the brain drain from Taiwan to the United States…

Integration of Technology into the Classroom: Case Studies.

ERIC Educational Resources Information Center

Johnson, D. LaMont, Ed.; Maddux, Cleborne D., Ed.; Liu, Leping, Ed.

This book contains the following case studies on the integration of technology in education: (1) "First Steps toward a Statistically Generated Information Technology Integration Model" (D. LaMont Johnson and Leping Liu); (2) "Case Studies: Are We Rejecting Rigor or Rediscovering Richness?" (Cleborne D. Maddux); (3)…

Making the Most of MASINT and Advanced Geospatial Intelligence

DTIC Science & Technology

2012-04-10

mining contracts and new job creation that ultimately supports economic development. This 22 type of forensic level analysis can make MASINT an...and Technology, ed. John D. Bossler (London: Taylor and Francis, 2002), 305 17 Jian Guo Liu and Philippa J. Mason, Essential Image Processing and

Lessons Learned in Part-of-Speech Tagging of Conversational Speech

DTIC Science & Technology

2010-10-01

for conversational speech recognition. In Plenary Meeting and Symposium on Prosody and Speech Processing. Slav Petrov and Dan Klein. 2007. Improved...inference for unlexicalized parsing. In HLT-NAACL. Slav Petrov. 2010. Products of random latent variable grammars. In HLT-NAACL. Brian Roark, Yang Liu

BIOINSPIRED DESIGN AND DIRECTED EVOLUTION OF IRON CONTAINING ENZYMES FOR GREENSYNTHETIC PROCESSES AND BIOREMEDIATION

EPA Science Inventory

SU833912
Title: Bioinspired Design and Directed Evolution of Iron Containing Enzymes for Green Synthetic Processes and BioremediationEdward I. Solomon, Shaun D. Wong, Lei Liu, Caleb B. Bell, IIICynthia Nolt-Helms
Project Period: August 15, 2008 - August 14,...

Author Correction: The evolutionary history of vertebrate RNA viruses.

PubMed

Shi, Mang; Lin, Xian-Dan; Chen, Xiao; Tian, Jun-Hua; Chen, Liang-Jun; Li, Kun; Wang, Wen; Eden, John-Sebastian; Shen, Jin-Jin; Liu, Li; Holmes, Edward C; Zhang, Yong-Zhen

2018-06-26

Change history: In this Article, author Li Liu should be associated with affiliation number 5 (College of Marine Sciences, South China Agricultural University, Guangzhou, Guangdong, China), rather than affiliation number 4 (Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang, China). This has been corrected online.

Electric Vehicle Sharing Planning and Operations

DOT National Transportation Integrated Search

2018-02-01

Dongfang Zhao (ORCID ID 0000-0002-5424-9915); Xiaopeng (Shaw) Li (ORCID ID 0000-0002-5264-3775); Yu Zhang (ORCID ID 0000-0003-1202-626X) This project includes literature review and proposing a model for EV planning and operations. We first conducted ...

NITROTYROSINATION OF A TUBULIN INDUCES EPITHELIAL BARRIER DYSFUNCTION

EPA Science Inventory

Nitrotyrosination of a-Tubulin Induces Epithelial Transport Dysfunction. Yuh-Chin Huang, Lisa Dailey, Wen-Li Zhang and Ilona Jaspers. ORD, Environmental Protection Agency and CEMLB, University of North Carolina

a-Tubulin undergoes a cyclic removal and readdition of tyrosin...

75 FR 32956 - Center for Scientific Review; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-10

... Center, 5701 Marinelli Road, Bethesda, MD 20852. Contact Person: Joanna M. Pyper, PhD, Scientific Review...: Yi-Hsin Liu, PhD, Scientific Review Officer, Center for Scientific Review, National Institutes of... . Name of Committee: Center for Scientific Review Special Emphasis Panel, RFA-DA-10-017: Seek, Test, and...

U.S. EPA, Pesticide Product Label, HEMPEL'S ANTIFOULING COMBIC 7699-5111 RED, 06/08/1989

EPA Pesticide Factsheets

2011-04-19

... II ... Dis ''''Ii" .d ,. II f" "ulss,n If U. Utt at tM h. .f ,lSticie. ."liu.ti.. .i1 .. ... PRACTiCM. TREATI'IENT IF SIIlUII(I. ',ill ,,..,11, • ht,lt "ntit, .f .ilt •• " "'itu. "htil stlllill If. ...

Novel Preclinical Testing Strategies for Treatment of Metastatic Pheochromocytoma

DTIC Science & Technology

2015-11-01

Girma M. Woldemichael b, Carole Sourbier c, Martin J. Lizak d, James F. Powers e, Arthur S. Tischler e, Karel Pacak a a Program in Reproductive... Petra Bullova, Svenja Nölting, Hana Turkova, James F. Powers, Qingsong Liu, Sylvie Guichard, Arthur S. Tischler, Ashley B. Grossman, and Karel Pacak

A Drug Discovery Partnership for Personalized Breast Cancer Therapy

DTIC Science & Technology

2012-09-01

flexible searches of compound databases using detailed pharmacophore and CoMFA QSAR results. (Months 9-24). 1,3,8-trihydroxyanthraquinone was taken...Cytochrome P450 Inhibitors- A Study of Their Potency and Selectivity”, J. Sridhar, J. Liu, C.L.K. Stevens, and M. Foroozesh, Society of Toxicology

Profiling Vocabulary in Psychology Journal Abstracts: A Comparison between Iranian and Anglo-American Journals

ERIC Educational Resources Information Center

Akbarian, Is'haaq; Ghanbarzadeh, Zahra; Shahri, Mohammad Afzali

2017-01-01

Lexical profiling has yielded fruitful results for language description and pedagogy (Liu, 2014), and particularly highlighted the significance of academic vocabulary for EFL learners in this process. This investigation, likewise, attempts to comparatively profile the vocabulary, more particularly the academic vocabulary, in the…

77 FR 60986 - Environmental Impacts Statements; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-05

.../2012, Contact: Liana Liu 360-753-9553. EIS No. 20120312, Final EIS, USFS, NV, Geothermal Leasing on the Humboldt-Toiyabe National Forest, To Facilitate the Development and Production of Geothermal Energy, Ely..., Contact: Jerald Weaver 360-378-2223. EIS No. 20120314, Draft EIS, WAPA, WY, Hermosa West Wind Energy...

Olfactory and visual responses of the long-legged chafer hoplia spectabilis medvedev (Coleoptera: Scarabaeidae) in Qinghai province, China

USDA-ARS?s Scientific Manuscript database

The long-legged chafer, Hoplia spectabilis Medvedev (Coleoptera: Scarabaeidae), has recently been recorded in outbreak numbers in pastureland of Qinghai province, China. It is causing significant damage to several species of woody shrubs, especially Hippophae neurocarpa Liu and Ho (Elaeagnaceae), D...

Erratum: Erratum to: Realistic interpretation of quantum mechanics and encounter-delayed-choice experiment

NASA Astrophysics Data System (ADS)

Long, GuiLu; Qin, Wei; Yang, Zhe; Li, Jun-Lin

2018-05-01

In our article [1] we made a mistake in citing ref. [32], which is the same as ref. [28]. We now replace ref. [32] with the correct reference "L. Hao, D. Liu, and G. L. Long, Sci. China Phys. Mech. Astron. 53, 1765 (2010)" [2].

Micro Power

DTIC Science & Technology

2004-02-01

GENERATOR ENERGIZED BY A MEMS BASED CHEMICAL- THERMAL REACTOR” 5-6 PI: Professor Robert F. Savinell Co-I(s): Professors C. C. Liu, M. H . Litt, and J. S...January 8, 2002 PI Chih-Ming Ho UCLA Yu-Chong Tai Caltech Siegfried Janson Henry Helvajian Aerospace Corporation H.Q. Yang Andrzej J. Przekwasa CFDRC Co

Educational Opportunities for Adults in California

ERIC Educational Resources Information Center

de Cos, Patricia L.

2004-01-01

Assembly member Carol Liu, Chair of the Assembly Select Committee on Adult Education, requested that the California Research Bureau prepare a report on adult education. The legislative request specified that the following topics be covered: (1) a definition of adult education; (2) recent information on student enrollment, funding sources and…

Liu Xin (first century BC-first century AD)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Astronomer to the Chinese war-lord Wang Mang. A hundred years before Ptolemy he constructed astronomical tables, and listed 1080 stars in six magnitude categories. He determined the year to be 365.2502 days. In AD 4, he organized a national congress on the modern scale, attended by 1000 scientists....

Fourteen-Day Subchronic Oral Toxicity Study of Nitroguanidine in Rats

DTIC Science & Technology

1988-06-01

Beckett , SGT Samuel S. Liu, BS, and SP4 Gary E. Mattison provided hematology support; SP4 Julius Harmon and Mary E. Lyons provided clinical...Count xlO6/^! xl03/|il White Blnod Cell Differential Neutro- Lympho- Eosino- Mono- phils cytes phils cytes % % % % 0 85D00308

Crossing scales and disciplines to achieve forest sustainability

Treesearch

Michael J. Papaik; Brian Sturtevant; Christian Messier

2008-01-01

Forest land managers are faced with unprecedented global pressures to produce resources for human consumption (e.g., Liu and Diamond 2005), while still maintaining essential ecosystem services benefiting society at multiple spatial scales (Costanza et al. 1997). These global pressures alone present daunting challenges to sustainable forest management (SFM) worldwide (...

Assessing Higher-Order Thinking Using a Networked Portfolio System with Peer Assessment

ERIC Educational Resources Information Center

Liu, Eric Zhi-Feng; Zhuo, Yi-Chin; Yuan, Shyan-Ming

2004-01-01

In the past, the quantitative evidences of portfolio assessment have been explored under online instruction. Liu, Lin, and Yuan provide a long-term measure of peer-self, peer-instructor and self-instructor correlation coefficients under networked innovative assessment procedures. Analytical results indicated that undergraduate students could…

Developing Collaborative Cyber Communities to Prepare Tomorrow's Teachers

ERIC Educational Resources Information Center

Lord, Gillian; Lomicka, Lara L.

2004-01-01

Computer-mediated exchange and interaction have become topics of debate and discussion in the past several years due to the growing interest in synchronous and asynchronous communication and their role in language acquisition, learning, and teaching (Liu, Moore, Graham, & Lee, 2002). This article offers a model for a collaborative course on…

422nd Brookhaven Lecture. Aerosols, Clouds and Climate: From Micro to Micro

ScienceCinema

Yangang Liu

2018-01-05

As scientists who study aerosols, clouds, and precipitation know, particles in the atmosphere interact with one another and affect the Earth's climate through a myriad of complex processes. Learn more about this topic from Yangang Liu as he presents "Aerosols, Clouds, and Climate: From Micro to Macro."

Computer Games Functioning as Motivation Stimulants

ERIC Educational Resources Information Center

Lin, Grace Hui Chin; Tsai, Tony Kung Wan; Chien, Paul Shih Chieh

2011-01-01

Numerous scholars have recommended computer games can function as influential motivation stimulants of English learning, showing benefits as learning tools (Clarke and Dede, 2007; Dede, 2009; Klopfer and Squire, 2009; Liu and Chu, 2010; Mitchell, Dede & Dunleavy, 2009). This study aimed to further test and verify the above suggestion,…

Genetics Home Reference: CATSPER1-related nonsyndromic male infertility

MedlinePlus

... Avenarius MR, Hildebrand MS, Zhang Y, Meyer NC, Smith LL, Kahrizi K, Najmabadi H, Smith RJ. Human male infertility caused by mutations in ... article on PubMed Central Hildebrand MS, Avenarius MR, Smith RJH. CATSPER-Related Male Infertility. 2009 Dec 3 [ ...

Three-dimensional wave field modeling by a collocated-grid finite-difference method in the anelastic model with surface topography

NASA Astrophysics Data System (ADS)

Wang, N.; Li, J.; Borisov, D.; Gharti, H. N.; Shen, Y.; Zhang, W.; Savage, B. K.

2016-12-01

We incorporate 3D anelastic attenuation into the collocated-grid finite-difference method on curvilinear grids (Zhang et al., 2012), using the rheological model of the generalized Maxwell body (Emmerich and Korn, 1987; Moczo and Kristek, 2005; Käser et al., 2007). We follow a conventional procedure to calculate the anelastic coefficients (Emmerich and Korn, 1987) determined by the Q(ω)-law, with a modification in the choice of frequency band and thus the relaxation frequencies that equidistantly cover the logarithmic frequency range. We show that such an optimization of anelastic coefficients is more accurate when using a fixed number of relaxation mechanisms to fit the frequency independent Q-factors. We use curvilinear grids to represent the surface topography. The velocity-stress form of the 3D isotropic anelastic wave equation is solved with a collocated-grid finite-difference method. Compared with the elastic case, we need to solve additional material-independent anelastic functions (Kristek and Moczo, 2003) for the mechanisms at each relaxation frequency. Based on the stress-strain relation, we calculate the spatial partial derivatives of the anelastic functions indirectly thereby saving computational storage and improving computational efficiency. The complex-frequency-shifted perfectly matched layer (CFS-PML) is used for the absorbing boundary condition based on the auxiliary difference equation (Zhang and Shen, 2010). The traction image method (Zhang and Chen, 2006) is employed for the free-surface boundary condition. We perform several numerical experiments including homogeneous full-space models and layered half-space models, considering both flat and 3D Gaussian-shape hill surfaces. The results match very well with those of the spectral-element method (Komatitisch and Tromp, 2002; Savage et al., 2010), verifying the simulations by our method in the anelastic model with surface topography.

Thermostaphylospora grisealba gen. nov., sp. nov., isolated from mushroom compost and transfer of Thermomonospora chromogena Zhang et al. 1998 to Thermostaphylospora chromogena comb. nov.

PubMed

Wu, Hao; Liu, Bin; Shao, Yuanyuan; Ou, Xiaoyun; Huang, Fuchang

2018-02-01

A novel thermophilic actinomycete, designated strain 3-12X T , was isolated from mushroom compost in Guangxi University, Nanning, China. The novel isolate contained meso-diaminopimelic acid as the diagnostic diamino acid and the whole-cell sugars were glucose and ribose. The predominant menaquinones were MK-9(H4) and MK-9(H6). The polar phospholipids were diphosphatidylglycerol, hydroxy-phosphatidylethanolamine, phosphatidylmethylethanolamine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylinositol mannoside, ninhydrin-positive phosphoglycolipids and glycolipids. Major fatty acids were so-C16 : 0 and C17 : 0. The G+C content of the genomic DNA was 74.6 %. The 16S rRNA gene sequence analysis showed that the closest phylogenetic neighbour of strain 3-12X T was Thermomonospora chromogena ATCC 43196 T (97.0 %), other closely related strains all belonged to the family Streptosporangiaceae and showed more than 6 % divergence. The chemotaxonomic characteristics of strain 3-12X T were significantly different from Thermomonospora chromogena ATCC 43196 T and DNA-DNA hybridization showed low relatedness (48.6-55.6 %) between them, so they should be different species. Thermomonospora chromogena was removed from the genus Thermomonospora by Zhang et al. 1998 on the basis of phylogenetic, chemotaxonomic and phenotypic evidence, but its taxonomic position remains uncertain. Based on the phenotypic and phylogenetic data, strain 3-12X T represents a novel species in a new genus in the family Streptosporangiaceae. The name Thermostaphylospora griseoalba gen. nov., sp. nov. is proposed. The type strain of Thermostaphylospora grisealba is 3-12X T (=DSM 46781 T =CGMCC 4.7160 T ). We also propose transferring Thermomonospora chromogenaZhang et al. 1998 to Thermostaphylospora chromogena comb. nov. (type strain ATCC 43196 T =JCM 6244 T ).

Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples.

PubMed

Vartanian, Jean-Pierre; Wain-Hobson, Simon

2002-05-28

Nuclear mtDNA sequences (numts) are a widespread family of paralogs evolving as pseudogenes in chromosomal DNA [Zhang, D. E. & Hewitt, G. M. (1996) TREE 11, 247-251 and Bensasson, D., Zhang, D., Hartl, D. L. & Hewitt, G. M. (2001) TREE 16, 314-321]. When trying to identify the species origin of an unknown DNA sample by way of an mtDNA locus, PCR may amplify both mtDNA and numts. Indeed, occasionally numts dominate confounding attempts at species identification [Bensasson, D., Zhang, D. X. & Hewitt, G. M. (2000) Mol. Biol. Evol. 17, 406-415; Wallace, D. C., et al. (1997) Proc. Natl. Acad. Sci. USA 94, 14900-14905]. Rhesus and cynomolgus macaque mtDNA haplotypes were identified in a study of oral polio vaccine samples dating from the late 1950s [Blancou, P., et al. (2001) Nature (London) 410, 1045-1046]. They were accompanied by a number of putative numts. To confirm that these putative numts were of macaque origin, a library of numts corresponding to a small segment of 12S rDNA locus has been made by using DNA from a Chinese rhesus macaque. A broad distribution was found with up to 30% sequence variation. Phylogenetic analysis showed that the evolutionary trajectories of numts and bona fide mtDNA haplotypes do not overlap with the signal exception of the host species; mtDNA fragments are continually crossing over into the germ line. In the case of divergent mtDNA sequences from old oral polio vaccine samples [Blancou, P., et al. (2001) Nature (London) 410, 1045-1046], all were closely related to numts in the Chinese macaque library.

EDITORIAL: Designer fabrication: nanotemplates get in shape Designer fabrication: nanotemplates get in shape

NASA Astrophysics Data System (ADS)

Demming, Anna

2013-02-01

People working in device design rarely see something that works without thinking how it could be made to work better. The work on anodic aluminum oxide materials in this issue provides a case in point [1]. Over the past century researchers have observed, manipulated and exploited the porous structures that result when anodizing aluminum in for example oxalic, sulfuric, and phosphoric acid solutions [1, 2]. The self-organized pore arrays have demonstrated the potential to facilitate high through-put, low-cost fabrication of nanocomposites as well as other nanostructures. The straight self-aligned nanochannels in porous anodic aluminum oxide (AAO) have long been accepted as an inherent property of these films and for many applications they are an attractive attribute. However, researchers in Taiwan have considered a novel manifestation of AAO materials which may enhance their natural attributes by generating arrays that bend [3]. Their work is an example of how even well studied systems continue to harbour surprises and scope for creative innovation. As the authors point out, 'This novel fan-out platform facilitates probing and handling many signals from different areas on a sample's surface and is therefore promising for applications in detection and manipulation at the nanoscale level'. It has long been recognized that the inter-pore distance, pore diameter and pore depth in AAO can be controlled by changing the anodization conditions. These accommodating features have motivated researchers to seek a better understanding of how to optimize fabrication conditions. A collaboration of researchers in Sweden, Chile and Uruguay studied the structural and optical properties of silver nanowires electrodeposited in commercially available nanoporous alumina templates, with a nominal pore diameter of 20 nm [4]. Their results revealed a decrease in the uniformity of pore filling with increasing deposition overpotential and suggested that overpotentials were preferred for the formation of single crystal silver nanowires. More recently Hyungjun Kim and colleagues at the Pohang University of Science and Technology in Korea combined atomic layer deposition of ruthenium with AAO templates to fabricate a range of metal nanostructures directly onto silicon substrates, including nanodots, nanowires and nanowire array devices [5]. Ruthenium has been intensively studied for semiconductor devices, for use in metal gate electrodes, capacitor electrodes for dynamic random access memories and seed layers for electrochemical plating of copper interconnect formation. The work may prove significant in the semiconductor device industry where the ability to integrate with existing silicon technology is an important advantage. According to recent research in China AAO templates may also benefit LED devices. Zhou and colleagues reported the fabrication of GaN LEDs by soft UV nanoimprint lithography based on a replication stamp of self-ordered AAO membrane for the first time [6]. Photonic crystal nanostructures had been mooted as a possible solution to the total internal reflection that diminishes the external quantum efficiency of GaN LED devices compared with the performance that theory predicts. Conventional approaches to photonic crystal fabrication, such as electron-beam lithography or focused ion-beam techniques are problematic to scale up to industrial scales. In contrast to this, AAO templates are well suited to scaling up. Zhou et al reported an enhancement to the photoluminescence intensity from their nano-patterned GaN LED sample of 41% [6]. The fan-out AAO channel structure reported by Liu and colleagues in this issue introduces a new versatility in the application of AAO templates [1]. They allow mapping of information from a small area at one end of the channels to a large area at the other end with a one-to-one correspondence, and may benefit building integrated circuits containing many elements. As the researchers explain, planar fan-out probes have already been used to investigate nanomaterials, such as the electrical properties of nanorods, but the two-dimensional geometry introduces unwanted noise as a result of the probe touching a region other than the sensed one. The researchers describe a mechanism for bending nanochannels grown from AAO to create non-planar fan-out structures that avoid the draw backs of planar architectures. The approach exploits the linear proportionality in AAO between the inter-distance and diameter of the nanochannels and the anodization voltage. Doubling the voltage induces a larger repulsion among the nanochannels in each cell. As a result their growth directions become oblique while the pore diameter and inter-pore distance increase accordingly. This year, 2013, marks the centenary of the development of the Bohr model of the atom, for which Niels Bohr won the Nobel Prize. The model built on Rutherford's previous model and in a similar manner each of the developments in fabricating nanostructures and devices based on AAO have built on previous knowledge but with the addition of creative inspiration, which makes all the difference. In fact Niels Bohr is said to have once chided someone 'No, no, you're not thinking; you're just being logical'. Anyone working in research will be aware that success in science and technology requires creativity at least as much as in the arts. Advances in nanofabrication empower that creativity, inspiring designs and bringing them from the realms of fantasy to reality. References [1] Liu C-Y, Lai M Y, Tsai K-T, Chang H-H, He J-H, Shiue J and Wang Y-L 2013 A novel vertical fan-out platform based on an array of curved anodic alumina nanochannels Nanotechnology 24 055306 [2] Verwey E J W 1935 Electrolytic conduction of a solid insulator at high fields. The formation of the anodic oxide film on aluminium Physica 2 1059-63 [3] Li A P, Müller F, Bimer A, Nielsch K and Gösele U 1998 Hexagonal pore arrays with a 50-420 nm interpore distance formed by self-organization in anodic alumina J. Appl. Phys. 84 6023-6 [4] Riveros G, Green S, Cortes A, Gómez H, Marotti R E and Dalchiele E A 2006 Silver nanowire arrays electrochemically grown into nanoporous anodic alumina templates Nanotechnology 17 561-70 [5] Kim W-H, Park S-J, Son J-Y and Kim H 2008 Ru nanostructure fabrication using an anodic aluminum oxide nanotemplate and highly conformal Ru atomic layer deposition Nanotechnology 19 045302 [6]Zhou W, Min G, Song Z, Zhang J, Liu Y and Zhang J 2010 Enhanced efficiency of light emitting diodes with a nano-patterned gallium nitride surface realized by soft UV nanoimprint lithography Nanotechnology 21 205304

Extreme soil erosion rates in citrus slope plantations and control strategies. A literature review

NASA Astrophysics Data System (ADS)

Cerdà, Artemi; Ángel González Peñaloza, Félix; Pereira, Paulo; Reyes Ruiz Gallardo, José; García Orenes, Fuensanta; Burguet, María

2013-04-01

Soil Erosion is a natural process that shapes the Earth. Due to the impact of agriculture, soil erosion rates increase, landforms show gullies and rills, and soils are depleted. In the Mediterranean, wheat, olive and vineyards were the main agriculture products, but new plantations are being found in sloping terrain due to the drip-irrigation. This new strategy results in the removal of the traditional terraces in order to make suitable for mechanization the agriculture plantation. Citrus is a clear example of the impact of the new chemical agriculture with a high investment in herbicides, pesticides, mechanisation, land levelling and drip computer controlled irrigation systems. The new plantation of citrus orchards is found in the Mediterranean, but also in California, Florida, China and Brazil. Chile, Argentina, and South Africa are other producers that are moving to an industrial production of citrus. This paper shows how the citrus plantations are found as one of the most aggressive plantation due to the increase in soil erosion, and how we can apply successful control strategies. The research into the high erosion rates of citrus orchard built on the slopes are mainly found in China (Wu et al., 1997; Xu et al., 2010; Wang et al., 2011; Wu et al., 2011; Liu et al., 2011; Lü et al., 2011; Xu et al., 2012) and in the Mediterranean (Cerdà and Jurgensen, 2008; 2009; Cerdà et al., 2009a; 2009b; Cerdà et al., 2011; 2012) Most of the research done devoted to the measurements of the soil losses but also some research is done related to the soil properties (Lu et al., 1997; Lü et al., 2012; Xu et al., 2012) and the impact of cover crops to reduce the soil losses (Lavigne et al., 2012; Le Bellec et al., 2012) and the use of residues such as dried citrus peel in order to reduce the soil losses. There are 116 million tonnes of citrus produced yearly, and this affects a large surface of the best land. The citrus orchards are moving from flood irrigated to drip irrigated land, and this contributes to increase the soil losses due to the sloping terrain. Although citrus is a world wide food, and occupy a large surface little is being researched on their impact on soil erosion, land degradation and strategies to control the soil, water and nutrient losses. This paper review the research developed until now and the results show that there is a poor background on this topic. It is necessary to develop research projects to improve the knowledge on the impact of citrus plantations on soil degradation and soil erosion. Another key information from the literature review done, is that most of the research was done in two regions of China and one of the Mediterranean. Definitively, a poor understanding of a huge environmental problem that need more scientific research. Acknowledgements The research projects GL2008-02879/BTE and LEDDRA 243857 supported this research. References Bombino, G., Denisi, P., Fortugno, D., Tamburino, V., Zema, D.A., Zimbone, S.M. 2010. Land spreading of solar-dried citrus peel to control runoff and soil erosion. WIT Transactions on Ecology and the Environment, 140, 145-154. Cerdà, A., Giménez Morera, A., Burguet, M., Arcenegui, V., González Peñaloza, F.A., García-Orenes, F., Pereira, P. 2012. The impact of the farming, abandonment and agricultural intensification on loss of water and soil. The example of the northern slopes of the Serra Grossa, Eastern Spain [El impacto del cultivo, el abandono y la intensificación de la agricultura en la pérdida de agua y suelo. el ejemplo de la vertiente norte de la serra grossa en el este peninsular] Cuadernos de Investigacion Geografica, 38 (1), 75-94. Cerdà, A., Jurgensen, M.F. 2008. The influence of ants on soil and water losses from an orange orchard in eastern Spain. Journal of Applied Entomology, 132 (4), 306-314. Cerdà, A., Jurgensen, M.F. 2011. Ant mounds as a source of sediment on citrus orchard plantations in eastern Spain. A three-scale rainfall simulation approach. Catena, 85 (3), 231-236. Cerdà, A., Jurgensen, M.F., Bodi, M.B. 2009. Effects of ants on water and soil losses from organically-managed citrus orchards in eastern Spain. Biologia, 64 (3), 527-531. Cerdà, A., Morera, A.G., Bodí, M.B. 2009. Soil and water losses from new citrus orchards growing on sloped soils in the western Mediterranean basin. Earth Surface Processes and Landforms, 34 (13), 1822-1830. Lavigne, C., Achard, R., Tixier, P., Lesueur Jannoyer, M. 2012. How to integrate cover crops to enhance sustainability in banana and citrus cropping systems. Acta Horticulturae, 928, 351-358. Le Bellec, F., Damas, O., Boullenger, G., Vannière, H., Lesueur Jannoyer, M., Tournebize, R., Ozier Lafontaine, H. 2012. Weed control with a cover crop (Neonotonia wightii) in mandarin orchards in Guadeloupe (FWI). Acta Horticulturae, 928, 359-366. Liu, Y., Tao, Y., Wan, K.Y., Zhang, G.S., Liu, D.B., Xiong, G.Y., Chen, F. 2012. Runoff and nutrient losses in citrus orchards on sloping land subjected to different surface mulching practices in the Danjiangkou Reservoir area of China. Agricultural Water Management, 110, 34-40. Lu, J., Wilson, M.J., Yu, J. 1997. Effects of trench planting and soil chiselling on soil properties and citrus production in hilly ultisols of China Soil and Tillage Research, 43 (3-4), 309-318. Lü, W., Zhang, H., Wu, Y., Cheng, J., Li, J., Wang, X. 2012. The impact of plant hedgerow in Three Gorges on the soil chemicophysical properties and soil erosion. Key Engineering Materials, 500, 142-148. Wang, L., Tang, L., Wang, X., Chen, F. 2010. Effects of alley crop planting on soil and nutrient losses in the citrus orchards of the Three Gorges Region. Soil and Tillage Research, 110 (2), 243-250. Wu J., Li Q., Yan L. 1997. Effect of intercropping on soil erosion in young citrus plantation - a simulation study. Chinese Journal of Applied Ecology, 8 (2), 143-146. Wu, D.-M., Yu, Y.-C., Xia, L.-Z., Yin, S.-X., Yang, L.-Z. 2011. Soil fertility indices of citrus orchard land along topographic gradients in the three gorges area of China. Pedosphere, 21 (6), 782-792. Xu, Q., Wang, T., Li, Z., Cai, C., Shi, Z., Jiang, C. 2010. Effect of soil conservation measurements on runoff, erosion and plant production: A case study on steeplands from the Three Gorges Area, China. Journal of Food, Agriculture and Environment, 8 (3-4 PART 2), 980-984. Xu, Q.X., Wang, T.W., Cai, C.F., Li, Z.X., Shi, Z.H. 2012. Effects of soil conservation on soil properties of citrus orchards in the Three-Gorges Area, China. Land Degradation and Development, 23 (1), 34-42.

China Report, Political, Sociological and Military Affairs

DTIC Science & Technology

1985-07-30

CENTRAL-SOUTH REGION More College Students Join CPC in Guangzhou Area (XINHUA, 28 Jun 85) 46 Briefs People’s Congress Session Scheduled ^’ c ...Zhang Xiangming, Doje Cering, Cau Xu, Danzeng, Jiangcun Luobu, Hu Songjie , Sengqen Lozong Guiancain, Jangzhong Zhaxidoje, Peng Zhe, (Luoje Dansu

Orphan Receptor TR3/nur77 and Apoptosis in Prostate Cancer Cells

DTIC Science & Technology

2004-07-01

chromosomal translocation identified in (Zhang et al. 1992b, Kastner et al. 1995, Mangelsdorf & extra-skeletal myxoid chondrosarcoma (Labelle et al...chromosomal 281-319. translocation in human chondrosarcomas is a highly potent Hoffman AD, Engelstein D, Bogenrieder T, Papandreou CN, transcriptional

JiaoShi-JiaZhang De HeZuo (Teacher-Parent Partnerships). ERIC Digest.

ERIC Educational Resources Information Center

Swick, Kevin J.

Research provides insight into parent attributes that support partnerships with teachers. These attributes include warmth, sensitivity, nurturance, the ability to listen, consistency, positive self-image, personal competence, and effective interpersonal skills. Researchers have cited positive attitudes, continuous teacher training, involvement in…

77 FR 76491 - Findings of Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Research Integrity (ORI) has taken final action in the following case: Shuang-Qing Zhang, Ph.D., Texas Tech... Sciences, TTUHSC, engaged in research misconduct in research supported by National Institute of General...

DEPOSITION DISTRICUTION AMONG THE PARALLEL PATHWAYS IN THE HUMAN LUNG CONDUCTING AIRWAY STRUCTURE.

EPA Science Inventory

DEPOSITION DISTRIBUTION AMONG THE PARALLEL PATHWAYS IN THE HUMAN LUNG CONDUCTING AIRWAY STRUCTURE. Chong S. Kim*, USEPA National Health and Environmental Effects Research Lab. RTP, NC 27711; Z. Zhang and C. Kleinstreuer, Department of Mechanical and Aerospace Engineering, North C...

STOTEN2016 Tong data

EPA Pesticide Factsheets

CTAG model inputs and outputsThis dataset is associated with the following publication:Tong, Z., R. Baldauf , V. Isakov , P.J. Deshmukh, and M. Zhang. Roadside vegetation barrier designs to mitigate near-road air pollution impacts. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 541: 920-927, (2016).

Thermal Conductivity Measurement Setup for Low Temperature Characterization of Laser Materials

DTIC Science & Technology

2014-09-01

JM, Kowalewski K, Guelzow J, Vitali V. Opt. Express. 2010;18:24770. 3. Sanamyan T, Kanskar M, Xiao Y, Kedlaya D, Dubinskii, M. Opt. Express. 2010;19...J ZHANG L MERKLE M DUBINSKIY N TER-GABRIELYAN V FROMZEL 14 INTENTIONALLY LEFT BLANK.

CBE Faculty and Staff

Science.gov Websites

About Us Research Staff Edward Arens Fred Bauman Gail Brager Darryl Dickerhoff Ali Ghahramani Uhl Zhe Wang Tom Webster Hui Zhang Research Affiliates Student Researchers Visiting Scholars Industry interdisciplinary group based in several academic departments, who collaborate regularly on research to improve the

Isostaticity in Cosserat Continuum

DTIC Science & Technology

2012-01-01

Geotech . Eng. Div. 106(4), 419–433 (1980) 13. Walker, D.M., Tordesillas, A., Thornton, C., Behringer, R.P., Zhang, J., Peters, J.F.: Percolating contact...thermomicromechanical approach to multiscale continuum modeling of dense granular materials. Acta Geotech . 3, 225–240 (2008) 17. Oda, M., Takemura, T

TRANSPORT AND DEPOSITION OF NANO-SIZE PARTICLES IN THE UPPER HUMAN RESPIRATORY AIRWAYS

EPA Science Inventory

TRANSPORT AND DEPOSITION OF NANO-SIZE PARTICLES IN THE UPPER HUMAN RESPIRATORY AIRWAYS. Zhe Zhang*, Huawei Shi, Clement Kleinstreuer, Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695-7910; Chong S. Kim, National Health and En...

TARGETED DELIVERY OF INHALED PROTEINS

EPA Science Inventory

ETD-02-047 (Martonen) GPRA # 10108

TARGETED DELIVERY OF INHALED PROTEINS
T. B. Martonen1, J. Schroeter2, Z. Zhang3, D. Hwang4, and J. S. Fleming5
1Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, Research Triangle Park...

ARSENIC EFFECTS ON TELOMERE AND TELOMERASE ACTIVITY

EPA Science Inventory

Arsenic effects on telomere and telomerase activity. T-C. Zhang, M. T. Schmitt, J. Mo, J. L. Mumford, National Research Council and U.S Environmental Protection Agency, NHEERL, Research Triangle Park, NC 27711
Arsenic is a known carcinogen and also an anticancer agent for acut...

Tian Tian | NREL

Science.gov Websites

Tian Tian Photo of Tian Tian Tian Tian Researcher III-Market Research Analysis Tian.Tian@nrel.gov Research Interests Renewable energy regulation Renewable energy business and financing models in various Muljadi, Yincheng Zhang, Mackay Miller, Weisheng Wang, and Jing Wang. "Comparative Study of Standards

Editorial: Serving the Optics and Photonics Community for 40 Years.

PubMed

Zhang, Xi-Cheng

2017-06-01

Editor-in-Chief Xi-Cheng Zhang celebrates Optics Letters' 40th anniversary by discussing the Journal's success and clarifying an editorial policy that balances the Journal's high standards with the fulfillment of its mission to support the greater optics and photonics community.

Opioids and the immune system: what is their mechanism of action?

PubMed Central

Eisenstein, Toby K

2011-01-01

There is a significant amount of literature showing that morphine and other opioids modulate immune responses. The findings support many mechanisms by which this may occur. In vitro experiments provide evidence for direct actions of opioids on immune cells using a variety of functional end points. When these drugs are given in vivo, a plethora of immune parameters are also altered. The paper in this issue of the journal by Zhang et al. provides new information on morphine alteration of immune cell subsets in the spleen and thymus of mice and the potential role of glucocorticoids in these observed phenomena. This Commentary reviews the in vitro activities of morphine on leucocytes, as well as other documented mechanisms by which morphine can alter immune function in vivo. LINKED ARTICLE This article is a commentary on Zhang et al., pp. 1829–1844 of this issue. To view this paper visit http://dx.doi.org/10.1111/j.1476-5381.2011.01475.x PMID:21627636

Brain MRI Tumor Detection using Active Contour Model and Local Image Fitting Energy

NASA Astrophysics Data System (ADS)

Nabizadeh, Nooshin; John, Nigel

2014-03-01

Automatic abnormality detection in Magnetic Resonance Imaging (MRI) is an important issue in many diagnostic and therapeutic applications. Here an automatic brain tumor detection method is introduced that uses T1-weighted images and K. Zhang et. al.'s active contour model driven by local image fitting (LIF) energy. Local image fitting energy obtains the local image information, which enables the algorithm to segment images with intensity inhomogeneities. Advantage of this method is that the LIF energy functional has less computational complexity than the local binary fitting (LBF) energy functional; moreover, it maintains the sub-pixel accuracy and boundary regularization properties. In Zhang's algorithm, a new level set method based on Gaussian filtering is used to implement the variational formulation, which is not only vigorous to prevent the energy functional from being trapped into local minimum, but also effective in keeping the level set function regular. Experiments show that the proposed method achieves high accuracy brain tumor segmentation results.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, T., E-mail: xietao@ustc.edu.cn; Key Laboratory of Geospace Environment, CAS, Hefei, Anhui 230026; Qin, H.

A unified ballooning theory, constructed on the basis of two special theories [Zhang et al., Phys. Fluids B 4, 2729 (1992); Y. Z. Zhang and T. Xie, Nucl. Fusion Plasma Phys. 33, 193 (2013)], shows that a weak up-down asymmetric mode structure is normally formed in an up-down symmetric equilibrium; the weak up-down asymmetry in mode structure is the manifestation of non-trivial higher order effects beyond the standard ballooning equation. It is shown that the asymmetric mode may have even higher growth rate than symmetric modes. The salient features of the theory are illustrated by investigating a fluid model formore » the ion temperature gradient (ITG) mode. The two dimensional (2D) analytical form of the ITG mode, solved in ballooning representation, is then converted into the radial-poloidal space to provide the natural boundary condition for solving the 2D mathematical local eigenmode problem. We find that the analytical expression of the mode structure is in a good agreement with finite difference solution. This sets a reliable framework for quasi-linear computation.« less

Growing surfaces with anomalous diffusion: Results for the fractal Kardar-Parisi-Zhang equation

NASA Astrophysics Data System (ADS)

Katzav, Eytan

2003-09-01

In this paper I study a model for a growing surface in the presence of anomalous diffusion, also known as the fractal Kardar-Parisi-Zhang equation (FKPZ). This equation includes a fractional Laplacian that accounts for the possibility that surface transport is caused by a hopping mechanism of a Levy flight. It is shown that for a specific choice of parameters of the FKPZ equation, the equation can be solved exactly in one dimension, so that all the critical exponents, which describe the surface that grows under FKPZ, can be derived for that case. Afterwards, the self-consistent expansion (SCE) is used to predict the critical exponents for the FKPZ model for any choice of the parameters and any spatial dimension. It is then verified that the results obtained using SCE recover the exact result in one dimension. At the end a simple picture for the behavior of the fractal KPZ equation is suggested and the upper critical dimension of this model is discussed.

Photochemical Control of the Distribution of Venusian Water and Comparison to Venus Express SOIR Observations

NASA Astrophysics Data System (ADS)

Parkinson, Chris; Yung, Yuk; Esposito, Larry; Gao, Peter; Bougher, Steve

2014-11-01

We use the JPL/Caltech 1-D KINETICS photochemical model to solve the continuity diffusion equation for the atmospheric constituent abundances and total number density as a function of radial distance from the planet Venus. The photochemistry of the Venus atmosphere from 58 to 112 km is modeled using an updated and expanded chemical scheme (Zhang et al., 2010; 2012), guided by the results of recent observations. We mainly follow Zhang et al. (2010; 2012) to guide our choice of boundary conditions for 40 species. We fit the SOIR Venus Express results of 1 ppm at 70-90 km (Bertaux et al (2007) by modeling water from between 10 - 35 ppm at our 58 km lower boundary and using an SO2 mixing ratio of 25 ppm as our nominal reference value. We then vary the SO2 mixing ratio at the lower boundary between 5 and 75 ppm and find that it can control the water distribution at higher altitudes.

Two new species of free-living marine nematodes (Nematoda: Oncholaimida: Enchelidiidae) from Maemul Island, Korea.

PubMed

Hong, Jung-Ho; Lee, Wonchoel

2014-04-04

Two new species of the family Enchelidiidae Filipjev, 1918 were collected from marine sediments near Maemul Island in South Korea: a new species of Abelbolla Huang & Zhang, 2004 and a new species of Ledovitia Filipjev, 1927. Abelbolla maemulensis sp. nov. is characterized by its small size (1,493 × 38 µm, body length × maximum body diameter); the presence of a circular amphid; the gubernacular apophysis with swollen distal tip; and the complex structure of the gubernaculum. It is close to Abelbolla huanghaiensis Huang & Zhang, 2004, but differs by the structure of gubernacular apophysis and body length (1,493 vs 2,303 µm). Ledovitia brevis sp. nov. can be separated from its congeners by its small size of body, the length of gubernacular apophysis, and the length of the spicules. It is close to Ledovitia pharetrata Wieser, 1953a, but differs by the length of the body (1,699 vs 2,640 µm) and the spicules (40 vs 100 µm).

Identification of QTLs for 14 Agronomically Important Traits in Setaria italica Based on SNPs Generated from High-Throughput Sequencing.

PubMed

Zhang, Kai; Fan, Guangyu; Zhang, Xinxin; Zhao, Fang; Wei, Wei; Du, Guohua; Feng, Xiaolei; Wang, Xiaoming; Wang, Feng; Song, Guoliang; Zou, Hongfeng; Zhang, Xiaolei; Li, Shuangdong; Ni, Xuemei; Zhang, Gengyun; Zhao, Zhihai

2017-05-05

Foxtail millet ( Setaria italica ) is an important crop possessing C4 photosynthesis capability. The S. italica genome was de novo sequenced in 2012, but the sequence lacked high-density genetic maps with agronomic and yield trait linkages. In the present study, we resequenced a foxtail millet population of 439 recombinant inbred lines (RILs) and developed high-resolution bin map and high-density SNP markers, which could provide an effective approach for gene identification. A total of 59 QTL for 14 agronomic traits in plants grown under long- and short-day photoperiods were identified. The phenotypic variation explained ranged from 4.9 to 43.94%. In addition, we suggested that there may be segregation distortion on chromosome 6 that is significantly distorted toward Zhang gu. The newly identified QTL will provide a platform for sequence-based research on the S. italica genome, and for molecular marker-assisted breeding. Copyright © 2017 Zhang et al.

Improving Comprehensive Medication Review Acceptance by Using a Standardized Recruitment Script: A Randomized Control Trial.

PubMed

Miguel, Alexander; Hall, Anna; Liu, Wei; Garrett, Jeremy; Ballew, Angel; Yang, Tsu-Hsaun; Segal, Richard

2017-01-01

The Centers for Medicare & Medicaid Services (CMS) require prescription drug plan sponsors to offer a comprehensive medication review (CMR) annually to eligible beneficiaries through the plans' Medication Therapy Management Programs (MTMPs). In 2011, the Pharmacy Quality Alliance endorsed the CMR completion rate as a quality measure for MTMPs, and CMS has adopted the measure into the 2016 CMS star ratings. CMS star ratings are used to describe the quality of plans to assist Medicare plan enrollees in choosing a plan and to determine quality bonus payments for Medicare Advantage plans. Star ratings are measured on a scale of 1 to 5, with 5 being the highest possible rating for an individual measure. Currently, the majority of plans score 2 stars or less on the CMR completion rate measure. To demonstrate the effectiveness of a standardized CMR recruitment script emphasizing the benefits of the service to increase acceptance of CMR offers among beneficiaries of a Medicare prescription drug plan. A CMR recruitment script, shaped by the Health Belief Model, was developed based on a previous pilot study. The original script described the CMR service but did not emphasize key benefits or barriers from the beneficiary perspective. The updated script aimed to enhance beneficiary understanding of the CMR service, explain the benefits from the beneficiary perspective, and address potential barriers to accepting the service. The updated script was tested during the 2012 MTMP enrollment in a randomized controlled experiment, using the original script as the control. The CMR service was offered to MTMP members via phone calls by live call agents who spoke with members who answered, using 1 of the 2 scripts. Both scripts asked members if they were willing to have a pharmacist call them back and perform a CMR at a later date. Two call attempts were made to all eligible beneficiaries. If contact was not made after 2 unsuccessful outreach attempts, a computer-generated voicemail message was left, and an informational letter regarding the MTMP and CMR was subsequently mailed. CMR acceptance rates, defined as the proportion of beneficiaries who spoke with a call agent and agreed to participate in the CMR service, divided by the total number of beneficiaries contacted who confirmed their membership with the Part D plan, were compared between those exposed to the original script and those exposed to the updated script. Multivariate logistic regression was employed to examine factors that may have influenced members' decisions regarding the offer to participate in CMRs. There were 105,701 beneficiaries in the first quarter of the MTMP 2012 enrollment who were eligible for the MTM service. Approximately 10% of eligible beneficiaries answered the live calls and listened to the scripts. On average, members who responded to calls were aged 68.9 years, prescribed 10.5 chronic medications, and had 6 different chronic conditions. Among members who answered the calls, 52.9% were exposed to the original script, and 47.1% heard the updated script. For the updated script, 48.2% of the members accepted the offer to be subsequently contacted by a pharmacist to complete the CMR, whereas 38.1% of members exposed to the original script agreed to the CMR offer. Logistic regression results indicated that members who received the updated script were 1.58 (95% CI = 1.45-1.72) times more likely to accept the CMR offer compared with those who received the original script. Among other factors, increased number of chronic medications (OR = 1.038, 95% CI = 1.020-1.057), increased number of disease conditions (OR = 1.039, 95% CI = 1.014-1.064), and previous involvement in the MTMP were positively associated with acceptance of the CMR offer. The updated script outperformed the original script in promoting member willingess to participate in a CMR by describing key components and emphasizing benefits of participation. CMR engagement remains a challenge for Medicare plan sponsors. This study demonstrates that to overcome common hurdles to CMR engagement, sponsors should seek strategies to educate members regarding MTM programs and the benefits and components of a CMR. No outside funding supported this study. Research for this study was conducted while Liu was a postdoctoral fellow at the University of Florida. Liu is currently an employee of the U.S. Food and Drug Administration (FDA). The views expressed here are those of the authors and not necessarily those of the FDA. Yang reports receiving a research fellowship funded by WellCare Health Plans at the time of this study. The authors report no other potential conflicts of interest. Study concept and design were primarily contributed by Yang, Segal, and Miguel, along with Hall, Liu, and Ballew. Miguel, Liu, Yang, Ballew, and Hall collected the data, which were analysed and interpreted primarily by Liu, along with Yang and Segal and assisted by the other authors. The manuscript was written primarily by Miguel, Hall, and Garret, along with Liu, Yang, and Ballew, and revised by Ballew, Segal, Hall, and Miguel, along with Liu and Yang.

Annunciation: Implementing an Emancipatory Communitarian Approach to Vocational Psychology

ERIC Educational Resources Information Center

McWhirter, Ellen Hawley; Blustein, David L.; Perry, Justin C.

2005-01-01

The informative and critical reactions from Fred Borgen; William Liu and Saba Rasheed Ali; Tod Sloan; and Kathy Gainor provide more reason and resolve to incorporate the emancipatory communitarian approach in vocational psychology. To move from a preoccupation with denunciation to the generation of solutions, or annunciation, we respond to each of…

PREGNANCY AND PERINATAL OUTCOMES IN RELATION TO DRINKING WATER ARSENIC EXPOSURE IN BAMEN, INNER MONGOLIA, CHINA

EPA Science Inventory

Pregnancy and Perinatal Outcomes in Relation to Drinking Water Arsenic Exposure in BaMen, Inner Mongolia, China
Danelle T. Lobdell, Zhixiong Ning, Richard K. Kwok, Judy Mumford, Zhi Yi Liu, Pauline Mendola

Introduction: Close to 40 million people worldwide are exposed t...

Comparative Analysis of Predictive Models for Liver Toxicity Using ToxCast Assays and Quantitative Structure-Activity Relationships (MCBIOS)

EPA Science Inventory

Comparative Analysis of Predictive Models for Liver Toxicity Using ToxCast Assays and Quantitative Structure-Activity Relationships Jie Liu1,2, Richard Judson1, Matthew T. Martin1, Huixiao Hong3, Imran Shah1 1National Center for Computational Toxicology (NCCT), US EPA, RTP, NC...

Learners' Preferences in Using Online Learning Resources

ERIC Educational Resources Information Center

Li, Sha; Leh, Amy; Fu, Yujian; Zhao, Xiang

2009-01-01

This article describes an action research in a graduate educational technology class. The study employed the Online Top-Down Modeling Model (Li & Liu, 2005) as a case in which the students used the learning resources from the course website to perform various learning activities. The findings of this research identify the students' eight…

"Speak Out. Act Up. Move Forward." Disobedience-Based Arts Education

ERIC Educational Resources Information Center

Kotin, Alison; Aguirre McGregor, Stella; Pellecchia, DeAnna; Schatz, Ingrid; Liu, Shaw Pong

2013-01-01

In this essay, Alison Kotin, Stella Aguirre McGregor, DeAnna Pellecchia, Ingrid Schatz, and Shaw Pong Liu reflect on their experiences working with public high school students to create "Speak Out. Act Up. Move Forward.," a performative response to current and historical acts of civil disobedience. The authors--a group of instructors…

New Theory and Algorithms for Scalable Data Fusion

DTIC Science & Technology

2013-07-14

neural spike train data analysis: state-of-the-art and future challenges. Nature Neuroscience , 7(5), May 2004. [11] T. Cai, W. Liu, and X. Luo. A...in which the goal is to predict users’ preferences for items (such as movies or music ) based on their and other users’ ratings of related items. The

Teacher Attitudes of Inclusion and Academic Performance of Students with Disabilities

ERIC Educational Resources Information Center

Sutton, Jonathan Earl

2013-01-01

Since the integration of the inclusion model, supported by the IDEA (1997), within public schools, teacher resistance and frustration has risen (Hardy, 1999). The climate of general education teachers' classrooms furthermore, has not been the same (Liu & Meyer, 2005). Key elements ensuring success of inclusion and the implementation of…

Data used in Xu et al., 2016

EPA Pesticide Factsheets

Mercury emissions data from anthropogenic sources as described in Xu et al., 2016.This dataset is associated with the following publication:Xu, X., N. Liu, M. Landis, X. Feng, and G. Qiu. Characteristics and distributions of atmospheric mercury emitted from anthropogenic sources in Guiyang, southwestern China. Acta Geochimica. Springer, Heidelburg, GERMANY, 1-11, (2016).

Comparative biology of three Scymnus lady beetles (Coleoptera: Coccinellidae): predators of Adelges tsugae (Homoptera: Adelgidae)

Treesearch

Wenhua Lu; Michael E. Montgomery

2000-01-01

Scymnus (Neopullus) sinuanodulus Yu et Yao, S. (N.) camptodromusYu et Liu, and Scymnus (Neopullus) n. sp. (in press) were collected in the People's Republic of China from hemlocks infested with the hemlock woolly adelgid, Adelges tsugae Annand. To date, 3 of the 14 provinces in China where...