Microbial Properties Database Editor Tutorial

EPA Science Inventory

A Microbial Properties Database Editor (MPDBE) has been developed to help consolidate microbial-relevant data to populate a microbial database and support a database editor by which an authorized user can modify physico-microbial properties related to microbial indicators and pat...

New Editors Appointed for Water Resources Research

NASA Astrophysics Data System (ADS)

2009-03-01

Praveen Kumar (University of Illinois at Urbana-Champaign), the newly appointed editor in chief of Water Resources Research (WRR), heads the new team of editors for the journal. The other editors are Tom Torgersen (University of Connecticut, Groton), who continues his editorship; Tissa Illangasekare (Colorado School of Mines, Golden); Graham Sander (Loughborough University, Loughborough, UK); and John Selker (Oregon State University, Corvallis). Hoshin Gupta (University of Arizona, Tucson) will join WRR at the end of 2009. The new editors will begin receiving submissions immediately. The incoming editorial board thanks outgoing editors Marc Parlange, Brian Berkowitz, Amilcare Porporato, and Scott Tyler, all of whom will assist during the transition.

TOAD Editor

NASA Technical Reports Server (NTRS)

Bingle, Bradford D.; Shea, Anne L.; Hofler, Alicia S.

1993-01-01

Transferable Output ASCII Data (TOAD) computer program (LAR-13755), implements format designed to facilitate transfer of data across communication networks and dissimilar host computer systems. Any data file conforming to TOAD format standard called TOAD file. TOAD Editor is interactive software tool for manipulating contents of TOAD files. Commonly used to extract filtered subsets of data for visualization of results of computation. Also offers such user-oriented features as on-line help, clear English error messages, startup file, macroinstructions defined by user, command history, user variables, UNDO features, and full complement of mathematical statistical, and conversion functions. Companion program, TOAD Gateway (LAR-14484), converts data files from variety of other file formats to that of TOAD. TOAD Editor written in FORTRAN 77.

Microbial properties database editor tutorial

USDA-ARS?s Scientific Manuscript database

A Microbial Properties Database Editor (MPDBE) has been developed to help consolidate microbialrelevant data to populate a microbial database and support a database editor by which an authorized user can modify physico-microbial properties related to microbial indicators and pathogens. Physical prop...

Conflicts of interest of editors of medical journals

PubMed Central

Minhajuddin, Abu

2018-01-01

Background Almost all medical journals now require authors to publicly disclose conflicts of interests (COI). The same standard and scrutiny is rarely employed for the editors of the journals although COI may affect editorial decisions. Methods We conducted a retrospective observational study to determine the prevalence and magnitude of financial relationships among editors of 60 influential US medical journals (10 each for internal medicine and five subspecialties: cardiology, gastroenterology, neurology, dermatology and allergy & immunology). Open Payments database was reviewed to determine the percentage of physician editors receiving payments and the nature and amount of these payments. Findings 703 unique physician editors were included in our analysis. 320/703 (46%) received 8659 general payments totaling $8,120,562. The median number of payments per editor was 9 (IQR 3–26) and the median amount per payment was $91 (IQR $21–441). The median total payment received by each editor in one year was $4,364 (IQR $319–23,143). 152 (48%) editors received payments more than $5,000 in a year, a threshold considered significant by the National Institutes of Health. COI policies for editors were available for 34/60 (57%) journals but only 7/34 (21%) publicly reported the disclosures and only 2 (3.%) reported the dollar amount received. Interpretation A significant number of editors of internal medicine and subspecialty medical journals have financial COI and very few are publicly disclosed. Specialty journal editors have more COI compared to general medicine journal editors. Current policies for disclosing COI for editors are inconsistent and do not comply with the recommended standards. PMID:29775468

ION Configuration Editor

NASA Technical Reports Server (NTRS)

Borgen, Richard L.

2013-01-01

The configuration of ION (Inter - planetary Overlay Network) network nodes is a manual task that is complex, time-consuming, and error-prone. This program seeks to accelerate this job and produce reliable configurations. The ION Configuration Editor is a model-based smart editor based on Eclipse Modeling Framework technology. An ION network designer uses this Eclipse-based GUI to construct a data model of the complete target network and then generate configurations. The data model is captured in an XML file. Intrinsic editor features aid in achieving model correctness, such as field fill-in, type-checking, lists of valid values, and suitable default values. Additionally, an explicit "validation" feature executes custom rules to catch more subtle model errors. A "survey" feature provides a set of reports providing an overview of the entire network, enabling a quick assessment of the model s completeness and correctness. The "configuration" feature produces the main final result, a complete set of ION configuration files (eight distinct file types) for each ION node in the network.

MPS Editor

NASA Technical Reports Server (NTRS)

Mathews, William S.; Liu, Ning; Francis, Laurie K.; OReilly, Taifun L.; Schrock, Mitchell; Page, Dennis N.; Morris, John R.; Joswig, Joseph C.; Crockett, Thomas M.; Shams, Khawaja S.

2011-01-01

Previously, it was time-consuming to hand-edit data and then set up simulation runs to find the effect and impact of the input data on a spacecraft. MPS Editor provides the user the capability to create/edit/update models and sequences, and immediately try them out using what appears to the user as one piece of software. MPS Editor provides an integrated sequencing environment for users. It provides them with software that can be utilized during development as well as actual operations. In addition, it provides them with a single, consistent, user friendly interface. MPS Editor uses the Eclipse Rich Client Platform to provide an environment that can be tailored to specific missions. It provides the capability to create and edit, and includes an Activity Dictionary to build the simulation spacecraft models, build and edit sequences of commands, and model the effects of those commands on the spacecraft. MPS Editor is written in Java using the Eclipse Rich Client Platform. It is currently built with four perspectives: the Activity Dictionary Perspective, the Project Adaptation Perspective, the Sequence Building Perspective, and the Sequence Modeling Perspective. Each perspective performs a given task. If a mission doesn't require that task, the unneeded perspective is not added to that project's delivery. In the Activity Dictionary Perspective, the user builds the project-specific activities, observations, calibrations, etc. Typically, this is used during the development phases of the mission, although it can be used later to make changes and updates to the Project Activity Dictionary. In the Adaptation Perspective, the user creates the spacecraft models such as power, data store, etc. Again, this is typically used during development, but will be used to update or add models of the spacecraft. The Sequence Building Perspective allows the user to create a sequence of activities or commands that go to the spacecraft. It provides a simulation of the activities and

A century of editors.

PubMed

Riley, R W

1983-07-08

They are unalike and far apart, these 13 past editors of The Journal. Between Nathan S. Davis's first issue and William R. Barclay's retirement, there was almost a century of change in medicine, society, the American Medical Association, prose style, and editorial needs. During these years, the editors ranged from the brilliant organizers John B. Hamilton and George H. Simmons to the diligent John H. Hollister and the devoted Johnson F. Hammond. There were editors with the hot determination of James C. Culbertson, John H. Talbott, and Robert H. Moser, and there were those with the cool precision of Austin Smith and Hugh H. Hussey. They varied from Morris Fishbein, who wrote and spoke "with the grade of an eagle in its unhindered soar," to Truman W. Miller, who wrote scarcely a word. Here, briefly, they are together.

DeviceEditor visual biological CAD canvas

PubMed Central

2012-01-01

Background Biological Computer Aided Design (bioCAD) assists the de novo design and selection of existing genetic components to achieve a desired biological activity, as part of an integrated design-build-test cycle. To meet the emerging needs of Synthetic Biology, bioCAD tools must address the increasing prevalence of combinatorial library design, design rule specification, and scar-less multi-part DNA assembly. Results We report the development and deployment of web-based bioCAD software, DeviceEditor, which provides a graphical design environment that mimics the intuitive visual whiteboard design process practiced in biological laboratories. The key innovations of DeviceEditor include visual combinatorial library design, direct integration with scar-less multi-part DNA assembly design automation, and a graphical user interface for the creation and modification of design specification rules. We demonstrate how biological designs are rendered on the DeviceEditor canvas, and we present effective visualizations of genetic component ordering and combinatorial variations within complex designs. Conclusions DeviceEditor liberates researchers from DNA base-pair manipulation, and enables users to create successful prototypes using standardized, functional, and visual abstractions. Open and documented software interfaces support further integration of DeviceEditor with other bioCAD tools and software platforms. DeviceEditor saves researcher time and institutional resources through correct-by-construction design, the automation of tedious tasks, design reuse, and the minimization of DNA assembly costs. PMID:22373390

Superficial Velocity Effects on HZ-PAN and AgZ-PAN for Kr/Xe Capture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welty, Amy Keil; Garn, Troy Gerry; Greenhalgh, Mitchell Randy

2016-04-01

Nearly all previous testing of HZ-PAN and AgZ-PAN was conducted at the same flow rate in order to maintain consistency among tests. This testing was sufficient for sorbent capacity determinations, but did not ensure that sorbents were capable of functioning under a range of flow regimes. Tests were conducted on both HZ-PAN and AgZ-PAN at superficial velocities between 20 and 700 cm/min. For HZ-PAN, Kr capacity increased from 60 mmol/kg to 110 mmol/kg as superficial velocity increased from 21 to 679 cm/min. Results for AgZ-PAN were similar, with capacity ranging from 72 to 124 mmol/kg over the same range ofmore » superficial. These results are promising for scaling up to process flows, demonstrating flexibility to operate in a broad range of superficial velocities while maintaining sorbent capacity. While preparing for superficial velocity testing it was also discovered that AgZ-PAN Xe capacity, previously observed to diminish over time, could be recovered with increased desorption temperature. Further, a substantial Xe capacity increase was observed. Previous room temperature capacities in the range of 22-25 mmol Xe/kg AgZ-PAN were increased to over 60 mmol Xe/kg AgZ-PAN. While this finding has not yet been fully explored to optimize activation and desorption temperatures, it is encouraging.« less

Editor's Choice Offered as a Service

NASA Astrophysics Data System (ADS)

Richman, Barbara T.

2010-06-01

Editor's Choice is now being offered as a service rather than on a subscription basis. As in the past, articles will be selected by collection editors with assistance from advisory panels. The selected articles will be listed on the AGU Web site (http://www.agu.org/pubs/journals/virtual/editors_choice/); these lists will be accessible to anyone. Those who are interested in reading the articles can access them through a personal or institutional subscription or can purchase them either individually or as part of a MultiChoice packet.

JSME: a free molecule editor in JavaScript.

PubMed

Bienfait, Bruno; Ertl, Peter

2013-01-01

A molecule editor, i.e. a program facilitating graphical input and interactive editing of molecules, is an indispensable part of every cheminformatics or molecular processing system. Today, when a web browser has become the universal scientific user interface, a tool to edit molecules directly within the web browser is essential. One of the most popular tools for molecular structure input on the web is the JME applet. Since its release nearly 15 years ago, however the web environment has changed and Java applets are facing increasing implementation hurdles due to their maintenance and support requirements, as well as security issues. This prompted us to update the JME editor and port it to a modern Internet programming language - JavaScript. The actual molecule editing Java code of the JME editor was translated into JavaScript with help of the Google Web Toolkit compiler and a custom library that emulates a subset of the GUI features of the Java runtime environment. In this process, the editor was enhanced by additional functionalities including a substituent menu, copy/paste, drag and drop and undo/redo capabilities and an integrated help. In addition to desktop computers, the editor supports molecule editing on touch devices, including iPhone, iPad and Android phones and tablets. In analogy to JME the new editor is named JSME. This new molecule editor is compact, easy to use and easy to incorporate into web pages. A free molecule editor written in JavaScript was developed and is released under the terms of permissive BSD license. The editor is compatible with JME, has practically the same user interface as well as the web application programming interface. The JSME editor is available for download from the project web page http://peter-ertl.com/jsme/

[The Chilean Association of Biomedical Journal Editors].

PubMed

Reyes, H

2001-01-01

On September 29th, 2000, The Chilean Association of Biomedical Journal Editors was founded, sponsored by the "Comisión Nacional de Investigación Científica y Tecnológica (CONICYT)" (the Governmental Agency promoting and funding scientific research and technological development in Chile) and the "Sociedad Médica de Santiago" (Chilean Society of Internal Medicine). The Association adopted the goals of the World Association of Medical Editors (WAME) and therefore it will foster "cooperation and communication among Editors of Chilean biomedical journals; to improve editorial standards, to promote professionalism in medical editing through education, self-criticism and self-regulation; and to encourage research on the principles and practice of medical editing". Twenty nine journals covering a closely similar number of different biomedical sciences, medical specialties, veterinary, dentistry and nursing, became Founding Members of the Association. A Governing Board was elected: President: Humberto Reyes, M.D. (Editor, Revista Médica de Chile); Vice-President: Mariano del Sol, M.D. (Editor, Revista Chilena de Anatomía); Secretary: Anna María Prat (CONICYT); Councilors: Manuel Krauskopff, Ph.D. (Editor, Biological Research) and Maritza Rahal, M.D. (Editor, Revista de Otorrinolaringología y Cirugía de Cabeza y Cuello). The Association will organize a Symposium on Biomedical Journal Editing and will spread information stimulating Chilean biomedical journals to become indexed in international databases and in SciELO-Chile, the main Chilean scientific website (www.scielo.cl).

WRR editor Ronald Cummings

NASA Astrophysics Data System (ADS)

1984-04-01

It has been nearly a year since Ronald Cummings took over as policy sciences editor of Water Resources Research (WRR), and in that time he has worked to make the journal live up to its role as “an interdisciplinary journal integrating research in the social and natural sciences of water.” Cummings takes the “interdisciplinary” part seriously. “I'd like to see a much broader range of policy issues presented to readers,” he says. “I would hope it would then stimulate interchange between our colleagues concerning evolving issues of the '80s and '90s.”Cummings brings a solid background as a resource economist to his 4-year term as editor, which began last January and runs until December 1987. Cummings succeeds Jared Cohon as policy sciences editor. Stephen J. Burges is the WRR editor for hydrological, physical, chemical, and biological sciences. Now a Professor of Economics and Director of the Program in Natural Resources Economics at the University of New Mexico, Cummings is a past president of the Association of Environmental and Resource Economists. He has been a consultant in matters of water resources management, forestry management, and energy policy for more than a decade, working on projects in both the United States and Latin America. Since joining the faculty at New Mexico in 1975, he has, among other things, worked with engineers at the Los Alamos National Laboratory in developing operation'management models for hot, dry rock geothermal systems.

Web-Based Media Contents Editor for UCC Websites

NASA Astrophysics Data System (ADS)

Kim, Seoksoo

The purpose of this research is to "design web-based media contents editor for establishing UCC(User Created Contents)-based websites." The web-based editor features user-oriented interfaces and increased convenience, significantly different from previous off-line editors. It allows users to edit media contents online and can be effectively used for online promotion activities of enterprises and organizations. In addition to development of the editor, the research aims to support the entry of enterprises and public agencies to the online market by combining the technology with various UCC items.

Remarks from a retiring Editor

NASA Astrophysics Data System (ADS)

Mansur, Louis K.

2015-10-01

At the end of 2015 I plan to step down as Chairman of Editors for the Journal of Nuclear Materials. I use the opportunity to express thoughts that have recurred to me but were muted in comparison with the day to day priorities of editorial work. The most important is that I hold the deepest gratitude for your enduring support- authors, reviewers, readers, the Advisory Editorial Board, and my fellow Editors.

29 CFR 793.8 - “News editor.”

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee who...

29 CFR 793.8 - “News editor.”

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee who...

29 CFR 793.8 - “News editor.”

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee who...

29 CFR 793.8 - “News editor.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee who...

29 CFR 793.8 - “News editor.”

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee who...

Editors' Fall Picks

ERIC Educational Resources Information Center

Hoffert, Barbara; Heilbrun, Margaret; Kuzyk, Raya; Kim, Ann; McCormack, Heather; Katterjohn, Anna; Burns, Ann; Williams, Wilda

2008-01-01

From the fall's cascade of great new books, "Library Journal's" editors select their favorites--a dark rendition of Afghan life, a look at the "self-esteem trap," a celebration of Brooklyn activism, and much more.

EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Nielsch, Kornelius

2012-01-01

On 1 January 2012 I will be assuming the position of Editor-in-Chief of the journal Semiconductor Science and Technology (SST). I am flattered by the confidence expressed in my ability to carry out this challenging job and I will try hard to justify this confidence. The previous Editor-in-Chief, Laurens Molenkamp, University of Würzburg, Germany, has worked tirelessly for the last ten years and has done an excellent job for the journal. Everyone at the journal is profoundly grateful for his leadership and for his achievements In 2012 several new members will join the Editorial Board: Professor Deli Wang (University of California, San Diego) with considerable expertise in semiconductor nanowires, Professor Saskia Fischer (Humboldt University, Berlin, Germany) with a background in semiconductor quantum devices, and Professor Erwin Kessels (Eindhoven University of Technology, Netherlands) with extensive experience in plasma processing of thin films and gate oxides. In particular, I want to express my gratitude to Professor Israel Bar-Joseph (Weizmann Institute of Science, Israel) and Professor Maria Tamargo (The City College of New York, USA), who will leave next year and who have vigorously served the Editorial Board for years. The journal has recently introduced a fast-track option for manuscripts. This option is a high-quality, high-profile outlet for new and important research across all areas of semiconductor research. Authors can expect to receive referee reports in less than 20 days from submission. Once accepted, you can expect the articles to be online within two or three weeks from acceptance and to be published in print in less than a month. Furthermore, all fast-track communications published in 2011 will be free to read for ten years. More detailed information on fast-track publication can be found on the following webpage: http://iopscience.iop.org/0268-1242/page/Fast track communications It is encouraging to see that since the journal introduced pre

New Editors Appointed for Sections of Journal of Geophysical Research

NASA Astrophysics Data System (ADS)

2009-04-01

New editors have been appointed for the Atmospheres, Biogeosciences, and Oceans sections of the Journal of Geophysical Research (JGR). Joost de Gouw (NOAA, Boulder, Colo.) and Renyi Zhang (Texas A&M, College Station) are filling the vacancies of retiring Atmospheres section editors John Austin and Jose Fuentes. De Gouw and Zhang join the continuing editors Steven Ghan and Yinon Rudich. Sara Pryor (Indiana University, Bloomington) is joining the Atmospheres section editorial board as an associate editor now; she will transition to editor in January 2010.

The pipes of pan.

PubMed

Chalif, David J

2004-12-01

The pipes of pan is the crowning achievement of Pablo Picasso's neoclassical period of the 1920s. This monumental canvas depicts a mythological Mediterranean scene in which two sculpted classical giants stare out, seemingly across the centuries, toward a distant and lost Arcadia. Picasso was influenced by Greco-Roman art during his travels in Italy, and his neoclassical works typically portray massive, immobile, and pensive figures. Pan and his pipes are taken directly from Greek mythological lore by Picasso and placed directly into 20th century art. He frequently turned to various mythological figures throughout his metamorphosing periods. The Pipes of Pan was also influenced by the painter's infatuation with the beautiful American expatriate Sara Murphy, and the finished masterpiece represents a revision of a previously conceived neoclassical work. The Pipes of Pan now hangs in the Musee Picasso in Paris.

ZED- A LINE EDITOR FOR THE DEC VAX

NASA Technical Reports Server (NTRS)

Scott, P. J.

1994-01-01

The ZED editor for the DEC VAX is a simple, yet powerful line editor for text, program source code, and non-binary data. Line editors can be superior to screen editors in some cases, such as executing complex multiple or conditional commands, or editing via slow modem lines. ZED excels in the area of text processing by using procedure files. For example, such procedures can reformat a file of addresses or remove all comment lines from a FORTRAN program. In addition to command files, ZED also features versatile search qualifiers, global changes, conditionals, on-line help, hexadecimal mode, space compression, looping, logical combinations of search strings, journaling, visible control characters, and automatic detabbing. The ZED editor was originally developed at Cambridge University in London and has been continuously enhanced since 1976. Users of the Cambridge implementation have devised such elaborate ZED procedures as chess games, calculators, and programs for evaluating Pi. This implementation of ZED strives to maintain the characteristics of the Cambridge editor. A complete ZED manual is included on the tape. ZED is written entirely in C for either batch or interactive execution on the DEC VAX under VMS 4.X and requires 80,896 bytes of memory. This program was released in 1988 and updated in 1989.

EDT mode for JED -- An advanced Unix text editor

NASA Astrophysics Data System (ADS)

McIlwrath, B. K.; Page, C. G.

This note describes Starlink extended EDT emulation for the JED editor. It provides a Unix text editor which can utilise the advanced facilities of DEC VTn00, xterm and similar terminals. JED in this mode provides a reasonably good emulation of the VAX/VMS editor EDT in addition to many extra facilities.

Inter- and Intraspecific Variations in the Pectoral Muscles of Common Chimpanzees (Pan troglodytes), Bonobos (Pan paniscus), and Humans (Homo sapiens).

PubMed

Potau, J M; Arias-Martorell, J; Bello-Hellegouarch, G; Casado, A; Pastor, J F; de Paz, F; Diogo, R

2018-01-01

We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens) . We have macroscopically dissected these muscles in six adult Pan troglodytes , five Pan paniscus of ages ranging from fetus to adult, and five adult Homo sapiens . Although Pan troglodytes are thought to lack a separate pectoralis abdominis muscle, we have identified this muscle in three of the Pan troglodytes ; none of the Pan paniscus , however, had this muscle. We have also found deep supernumerary fascicles in the pectoralis major of two Pan troglodytes and all five Pan paniscus . In all six Pan troglodytes , the pectoralis minor was inserted at the supraspinatus tendon, while, in Pan paniscus and Homo sapiens , it was inserted at the coracoid process of the scapula. Some of the anatomic features and variations of these muscles in common chimpanzees and bonobos are similar to those found in humans, therefore enhancing our knowledge of primate comparative anatomy and evolution and also shedding light on several clinical issues.

Inter- and Intraspecific Variations in the Pectoral Muscles of Common Chimpanzees (Pan troglodytes), Bonobos (Pan paniscus), and Humans (Homo sapiens)

PubMed Central

Arias-Martorell, J.; Bello-Hellegouarch, G.; Casado, A.; Pastor, J. F.; de Paz, F.; Diogo, R.

2018-01-01

We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens). We have macroscopically dissected these muscles in six adult Pan troglodytes, five Pan paniscus of ages ranging from fetus to adult, and five adult Homo sapiens. Although Pan troglodytes are thought to lack a separate pectoralis abdominis muscle, we have identified this muscle in three of the Pan troglodytes; none of the Pan paniscus, however, had this muscle. We have also found deep supernumerary fascicles in the pectoralis major of two Pan troglodytes and all five Pan paniscus. In all six Pan troglodytes, the pectoralis minor was inserted at the supraspinatus tendon, while, in Pan paniscus and Homo sapiens, it was inserted at the coracoid process of the scapula. Some of the anatomic features and variations of these muscles in common chimpanzees and bonobos are similar to those found in humans, therefore enhancing our knowledge of primate comparative anatomy and evolution and also shedding light on several clinical issues. PMID:29581990

STEVE -- a thinking person's screen editor

NASA Astrophysics Data System (ADS)

Fish, Adrian

STEve is an acronym for STarlink EVE and is an extended EDT-style EVE editor for use at Starlink nodes. The facility provides extra commands which are not part of standard EVE, and improves on one or two of the standard EVE commands. Help on all topics and keys is available from within the editor. The extensions and modifications present in STEve are particularly useful to Starlink users.

Professional Editing Strategies Used by Six Editors

ERIC Educational Resources Information Center

Bisaillon, Jocelyne

2007-01-01

Identifying the approach used by those revision experts par excellence--that is, professional editors--should enable researchers to better grasp the revision process. To further explore this hypothesis, the author conducted research among professional editors, six of whom she filmed as they engaged in their practice. An analysis of their work…

Precision Photometry and Astrometry from Pan-STARRS

NASA Astrophysics Data System (ADS)

Magnier, Eugene A.; Pan-STARRS Team

2018-01-01

The Pan-STARRS 3pi Survey has been calibrated with excellent precision for both astrometry and photometry. The Pan-STARRS Data Release 1, opened to the public on 2016 Dec 16, provides photometry in 5 well-calibrated, well-defined bandpasses (grizy) astrometrically registered to the Gaia frame. Comparisons with other surveys illustrate the high quality of the calibration and provide tests of remaining systematic errors in both Pan-STARRS and those external surveys. With photometry and astrometry of roughly 3 billion astronomical objects, the Pan-STARRS DR1 has substantial overlap with Gaia, SDSS, 2MASS and other surveys. I will discuss the astrometric tie between Pan-STARRS DR1 and Gaia and show comparisons between Pan-STARRS and other large-scale surveys.

Linguistic Prescriptivism in Letters to the Editor

ERIC Educational Resources Information Center

Lukac, Morana

2016-01-01

The public's concern with the fate of the standard language has been well documented in the history of the complaint tradition. The print media have for centuries featured letters to the editor on questions of language use. This study examines a corpus of 258 language-related letters to the editor published in the English-speaking print media. By…

A model of the biogeographical journey from Proto-pan to Pan paniscus.

PubMed

Myers Thompson, Jo A

2003-04-01

Pan paniscus is unique in the group of African apes because of its range south of the Congo River. Examination of the bio-geographical journey of the genus Pan to the species P. paniscus is important when discussing the evolution of African apes. This paper is a review of the paleo-geographic events, the zoogeography, and faunal sorting which influenced P. paniscus divergence from the Proto-pan ancestor within the recent Miocene through Pliocene Epochs, approximately 10-2 MYA. Finally, by elucidating modern day evidence of food plant forms in the southern periphery exploited by P. paniscus in the forest/savanna mosaic habitat, we are able to conclude with those extrinsic events that most influenced the occurrence and distribution of P. paniscus.

Academic Degradation and the Retreat of the Editors: Academic Irregularities and the Spreading of Academic Corruption from an Editor's Perspective

ERIC Educational Resources Information Center

Xun, Gong

2007-01-01

Against the backdrop of the grave academic crisis in China, editors have become the objects of wooing, favor-currying, connections-seeking, and collusions; they have been targeted for attacks, plots, extortions, and encroachments. Editing and publishing have become avenues for academic irregularities and academic corruption. Editors have the power…

Views of Iranian medical journal editors on medical research publication.

PubMed

Etemadi, Arash; Raiszadeh, Farbod; Alaeddini, Farshid; Azizi, Fereidoun

2004-01-01

Medical journal editors play an important role in optimizing research publication. This study evaluates the views of Iranian medical journal editors, and their knowledge of medical publication standards. In May 2001, 51 editors from all journals approved by the Ministry of Health were invited to participate, 27 of whom completed the study. A self-administered questionnaire, based on the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URMS) was used which consisted of 28 questions in 9 subject fields. These fields included: peer review, conflicts of interest, authorship criteria, publication ethics, duplicate publication, mass media, advertising, competing manuscripts, and the Internet. The knowledge of the editors was assessed by a scoring system, with a range of -46 to +44 points. Twenty-three of the participants were editors-in-chief and 4 were managing editors. Their average age was 47.3 +/- 8.7 years and 25 were male. All journals were peer-reviewed, most having 2 or 3 reviewers for each manuscript. Of the journals, 92.6% accepted or rejected an article on the basis of the views of most reviewers and 52%, sometimes or always, used a statistician as a reviewer. Most of the editors believed that writing the first draft and designing the study are authorship criteria, and most of them believed that these 2 are stated in URMS. Seven journals (25.9%) never published advertisements. Among journals that sold advertisements, the most popular policy (85%) was the rejection of advertisements because they advertised harmful products. Out of 27 journals, 12 were accessible on the Internet, and 7 had independent websites. Of the editors, 81.5% thought that a website is useful for their journal. The average knowledge score of the editors was 6.5 +/- 7.5. None had a negative score, 33% scored zero, 45% obtained average scores and 22% obtained good scores. The results show that peer review is favored by all the editors studied, though it seems that

Data Sharing: A New Editorial Initiative of the International Committee of Medical Journal Editors. Implications for the Editors´ Network.

PubMed

Alfonso, Fernando; Adamyan, Karlen; Artigou, Jean-Yves; Aschermann, Michael; Boehm, Michael; Buendia, Alfonso; Chu, Pao-Hsien; Cohen, Ariel; Cas, Livio Dei; Dilic, Mirza; Doubell, Anton; Echeverri, Dario; Enç, Nuray; Ferreira-González, Ignacio; Filipiak, Krzysztof J; Flammer, Andreas; Fleck, Eckart; Gatzov, Plamen; Ginghina, Carmen; Goncalves, Lino; Haouala, Habib; Hassanein, Mahmoud; Heusch, Gerd; Huber, Kurt; Hulín, Ivan; Ivanusa, Mario; Krittayaphong, Rungroj; Lau, Chu-Pak; Marinskis, Germanas; Mach, François; Moreira, Luiz Felipe; Nieminen, Tuomo; Oukerraj, Latifa; Perings, Stefan; Pierard, Luc; Potpara, Tatjana; Reyes-Caorsi, Walter; Rim, Se-Joong; Rødevand, Olaf; Saade, Georges; Sander, Mikael; Shlyakhto, Evgeny; Timuralp, Bilgin; Tousoulis, Dimitris; Ural, Dilek; Piek, J J; Varga, Albert; Lüscher, Thomas F

2017-05-01

The International Committee of Medical Journal Editors (ICMJE) provides recommendations to improve the editorial standards and scientific quality of biomedical journals. These recommendations range from uniform technical requirements to more complex and elusive editorial issues including ethical aspects of the scientific process. Recently, registration of clinical trials, conflicts of interest disclosure, and new criteria for authorship - emphasizing the importance of responsibility and accountability-, have been proposed. Last year, a new editorial initiative to foster sharing of clinical trial data was launched. This review discusses this novel initiative with the aim of increasing awareness among readers, investigators, authors and editors belonging to the Editors´ Network of the European Society of Cardiology. Resumo O Comitê Internacional de Editores de Revistas Médicas (ICMJE) fornece recomendações para aprimorar o padrão editorial e a qualidade científica das revistas biomédicas. Tais recomendações variam desde requisitos técnicos de uniformização até assuntos editoriais mais complexos e elusivos, como os aspectos éticos do processo científico. Recentemente, foram propostos registro de ensaios clínicos, divulgação de conflitos de interesse e novos critérios de autoria, enfatizando a importância da responsabilidade e da responsabilização. No último ano, lançou-se uma nova iniciativa editorial para fomentar o compartilhamento dos dados de ensaios clínicos. Esta revisão discute essa nova iniciativa visando a aumentar a conscientização de leitores, investigadores, autores e editores filiados à Rede de Editores da Sociedade Europeia de Cardiologia.

Data Sharing: A New Editorial Initiative of the International Committee of Medical Journal Editors. Implications for the Editors´ Network.

PubMed

Alfonso, Fernando; Adamyan, Karlen; Artigou, Jean Yves; Aschermann, Michael; Boehm, Michael; Buendia, Alfonso; Chu, Pao Hsien; Cohen, Ariel; Cas, Livio Dei; Dilic, Mirza; Doubell, Anton; Echeverri, Dario; Enç, Nuray; Ferreira-González, Ignacio; Filipiak, Krzysztof J; Flammer, Andreas; Fleck, Eckart; Gatzov, Plamen; Ginghina, Carmen; Goncalves, Lino; Haouala, Habib; Hassanein, Mahmoud; Heusch, Gerd; Huber, Kurt; Hulín, Ivan; Ivanusa, Mario; Krittayaphong, Rungroj; Lau, Chu Pak; Marinskis, Germanas; Mach, François; Moreira, Luiz Felipe; Nieminen, Tuomo; Oukerraj, Latifa; Perings, Stefan; Pierard, Luc; Potpara, Tatjana; Reyes-Caorsi, Walter; Rim, Se Joong; Rødevand, Olaf; Saade, Georges; Sander, Mikael; Shlyakhto, Evgeny; Timuralp, Bilgin; Tousoulis, Dimitris; Ural, Dilek; Piek, J J; Varga, Albert; Lüscher, Thomas F

2017-06-01

The International Committee of Medical Journal Editors (ICMJE) provides recommendations to improve the editorial standards and scientific quality of biomedical journals. These recommendations range from uniform technical requirements to more complex and elusive editorial issues including ethical aspects of the scientific process. Recently, registration of clinical trials, conflicts of interest disclosure, and new criteria for authorship -emphasizing the importance of responsibility and accountability-, have been proposed. Last year, a new editorial initiative to foster sharing of clinical trial data was launched. This review discusses this novel initiative with the aim of increasing awareness among readers, investigators, authors and editors belonging to the Editors´ Network of the European Society of Cardiology.

Investigation of needleless electrospun PAN nanofiber mats

NASA Astrophysics Data System (ADS)

Sabantina, Lilia; Mirasol, José Rodríguez; Cordero, Tomás; Finsterbusch, Karin; Ehrmann, Andrea

2018-04-01

Polyacrylonitrile (PAN) can be spun from a nontoxic solvent (DMSO, dimethyl sulfoxide) and is nevertheless waterproof, opposite to the biopolymers which are spinnable from aqueous solutions. This makes PAN an interesting material for electrospinning nanofiber mats which can be used for diverse biotechnological or medical applications, such as filters, cell growth, wound healing or tissue engineering. On the other hand, PAN is a typical base material for producing carbon nanofibers. Nevertheless, electrospinning PAN necessitates convenient spinning parameters to create nanofibers without too many membranes or agglomerations. Thus we have studied the influence of spinning parameters on the needleless electrospinning process of PAN dissolved in DMSO and the resulting nanofiber mats.

A Visual Editor in Java for View

NASA Technical Reports Server (NTRS)

Stansifer, Ryan

2000-01-01

In this project we continued the development of a visual editor in the Java programming language to create screens on which to display real-time data. The data comes from the numerous systems monitoring the operation of the space shuttle while on the ground and in space, and from the many tests of subsystems. The data can be displayed on any computer platform running a Java-enabled World Wide Web (WWW) browser and connected to the Internet. Previously a special-purpose program bad been written to display data on emulations of character-based display screens used for many years at NASA. The goal now is to display bit-mapped screens created by a visual editor. We report here on the visual editor that creates the display screens. This project continues the work we bad done previously. Previously we had followed the design of the 'beanbox,' a prototype visual editor created by Sun Microsystems. We abandoned this approach and implemented a prototype using a more direct approach. In addition, our prototype is based on newly released Java 2 graphical user interface (GUI) libraries. The result has been a visually more appealing appearance and a more robust application.

Editors' Fall Picks

ERIC Educational Resources Information Center

Heilbrun, Margaret; McCormack, Heather; Katterjohn, Anna; Kuzyk, Raya; Roncevic, Mirela; Fox, Bette-Lee; Hoffert, Barbara

2009-01-01

"Library Journal's" review editors select fall titles readers won't want to miss--"Waiting on a Train: The Embattled Future of Passenger Rail Service" (James McCommons); "Happy" (Alex Lemon); "Free for All: Joe Papp, the Public, and the Greatest Theater Story Ever Told" (Kenneth Turan & Joseph Papp); "In My Father's Shadow: A Daughter Remembers…

Editors' Spring Picks

ERIC Educational Resources Information Center

Library Journal, 2011

2011-01-01

While they do not represent the rainbow of reading tastes American public libraries accommodate, Book Review editors are a wildly eclectic bunch. One look at their bedside tables and ereaders would reveal very little crossover. This article highlights an eclectic array of spring offerings ranging from print books to an audiobook to ebook apps. It…

Data Sharing: A New Editorial Initiative of the International Committee of Medical Journal Editors. Implications for the Editors' Network.

PubMed

Alfonso, Fernando; Adamyan, Karlen; Artigou, Jean-Yves; Aschermann, Michael; Boehm, Michael; Buendia, Alfonso; Chu, Pao-Hsien; Cohen, Ariel; Cas, Livio Dei; Dilic, Mirza; Doubell, Anton; Echeverri, Dario; Enç, Nuray; Ferreira-González, Ignacio; Filipiak, Krzysztof J; Flammer, Andreas; Fleck, Eckart; Gatzov, Plamen; Ginghina, Carmen; Goncalves, Lino; Haouala, Habib; Hassanein, Mahmoud; Heusch, Gerd; Huber, Kurt; Hulín, Ivan; Ivanusa, Mario; Krittayaphong, Rungroj; Lau, Chu-Pak; Marinskis, Germanas; Mach, François; Moreira, Luiz Felipe; Nieminen, Tuomo; Oukerraj, Latifa; Perings, Stefan; Pierard, Luc; Potpara, Tatjana; Reyes-Caorsi, Walter; Rim, Se-Joong; Rødevand, Olaf; Saade, Georges; Sander, Mikael; Shlyakhto, Evgeny; Timuralp, Bilgin; Tousoulis, Dimitris; Ural, Dilek; Piek, J J; Varga, Albert; Lüscher, Thomas F

The International Committee of Medical Journal Editors (ICMJE) provides recommendations to improve the editorial standards and scientific quality of biomedical journals. These recommendations range from uniform technical requirements to more complex and elusive editorial issues including ethical aspects of the scientific process. Recently, registration of clinical trials, conflicts of interest disclosure, and new criteria for authorship - emphasizing the importance of responsibility and accountability -, have been proposed. Last year, a new editorial initiative to foster sharing of clinical trial data was launched. This review discusses this novel initiative with the aim of increasing awareness among readers, investigators, authors and editors belonging to the Editors' Network of the European Society of Cardiology. Copyright © 2017. Publicado por Masson Doyma México S.A.

Clinical Evaluation of Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): Recommendations from the 2013 PANS Consensus Conference

PubMed Central

Frankovich, Jennifer; Cooperstock, Michael; Cunningham, Madeleine W.; Latimer, M. Elizabeth; Murphy, Tanya K.; Pasternack, Mark; Thienemann, Margo; Williams, Kyle; Walter, Jolan; Swedo, Susan E.

2015-01-01

Abstract On May 23 and 24, 2013, the First PANS Consensus Conference was convened at Stanford University, calling together a geographically diverse group of clinicians and researchers from complementary fields of pediatrics: General and developmental pediatrics, infectious diseases, immunology, rheumatology, neurology, and child psychiatry. Participants were academicians with clinical and research interests in pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS) in youth, and the larger category of pediatric acute-onset neuropsychiatric syndrome (PANS). The goals were to clarify the diagnostic boundaries of PANS, to develop systematic strategies for evaluation of suspected PANS cases, and to set forth the most urgently needed studies in this field. Presented here is a consensus statement proposing recommendations for the diagnostic evaluation of youth presenting with PANS. PMID:25325534

Data Sharing: A New Editorial Initiative of the International Committee of Medical Journal Editors. Implications for the Editors´ Network

PubMed Central

Alfonso, Fernando; Adamyan, Karlen; Artigou, Jean-Yves; Aschermann, Michael; Boehm, Michael; Buendia, Alfonso; Chu, Pao-Hsien; Cohen, Ariel; Cas, Livio Dei; Dilic, Mirza; Doubell, Anton; Echeverri, Dario; Enç, Nuray; Ferreira-González, Ignacio; Filipiak, Krzysztof J.; Flammer, Andreas; Fleck, Eckart; Gatzov, Plamen; Ginghina, Carmen; Goncalves, Lino; Haouala, Habib; Hassanein, Mahmoud; Heusch, Gerd; Huber, Kurt; Hulín, Ivan; Ivanusa, Mario; Krittayaphong, Rungroj; Lau, Chu-Pak; Marinskis, Germanas; Mach, François; Moreira, Luiz Felipe; Nieminen, Tuomo; Oukerraj, Latifa; Perings, Stefan; Pierard, Luc; Potpara, Tatjana; Reyes-Caorsi, Walter; Rim, Se-Joong; Rødevand, Olaf; Saade, Georges; Sander, Mikael; Shlyakhto, Evgeny; Timuralp, Bilgin; Tousoulis, Dimitris; Ural, Dilek; Piek, J. J.; Varga, Albert; Lüscher, Thomas F.

2017-01-01

The International Committee of Medical Journal Editors (ICMJE) provides recommendations to improve the editorial standards and scientific quality of biomedical journals. These recommendations range from uniform technical requirements to more complex and elusive editorial issues including ethical aspects of the scientific process. Recently, registration of clinical trials, conflicts of interest disclosure, and new criteria for authorship - emphasizing the importance of responsibility and accountability-, have been proposed. Last year, a new editorial initiative to foster sharing of clinical trial data was launched. This review discusses this novel initiative with the aim of increasing awareness among readers, investigators, authors and editors belonging to the Editors´ Network of the European Society of Cardiology. PMID:28591318

The WebACS - An Accessible Graphical Editor.

PubMed

Parker, Stefan; Nussbaum, Gerhard; Pölzer, Stephan

2017-01-01

This paper is about the solution to accessibility problems met when implementing a graphical editor, a major challenge being the comprehension of the relationships between graphical components, which needs to be guaranteed for blind and vision impaired users. In the concrete case the HTML5 canvas and Javascript were used. Accessibility was reached by implementing a list view of elements, which also enhances the usability of the editor.

Pan-Eurasian experiment (PEEX) establishing a process towards high level Pan-Eurasian atmosphere-ecosystem observation networks

NASA Astrophysics Data System (ADS)

Lappalainen, Hanna K.; Petäjä, Tuukka; Zaytzeva, Nina; Viisanen, Yrjö; Kotlyakov, Vladimir; Kasimov, Nikolay; Bondur, Valery; Matvienko, Gennady; Zilitinkevich, Sergej; Kulmala, Markku

2014-05-01

Pan-Eurasian Experiment (PEEX) is a new multidisciplinary research approach aiming at resolving the major uncertainties in the Earth system science and global sustainability questions in the Arctic and boreal Pan-Eurasian regions (Kulmala et al. 2011). The main goal of PEEX Research agenda is to contribute to solving the scientific questions that are specifically important for the Pan-Eurasian region in the coming years, in particular the global climate change and its consequences to nature and human society. Pan Eurasian region represents one the Earth most extensive areas of boreal forest (taiga) and the largest natural wetlands, thus being a significant source area of trace gas emissions, biogenic aerosol particles, and source and sink area for the greenhouse gas (GHG) exchange in a global scale (Guenther et al. 1995, Timkovsky et al. 2010, Tunved et al. 2006, Glagolev et al. 2010). One of the first activities of the PEEX initiative is to establish a process towards high level Pan-Eurasian Observation Networks. Siberian region is currently lacking a coordinated, coherent ground based atmosphere-ecosystem measurement network, which would be crucial component for observing and predicting the effects of climate change in the Northern Pan- Eurasian region The vision of the Pan-Eurasion network will be based on a hierarchical SMEAR-type (Stations Measuring Atmosphere-Ecosystem Interactions) integrated land-atmosphere observation system (Hari et al. 2009). A suite of stations have been selected for the Preliminary Phase of PEEX Observation network. These Preliminary Phase stations includes the SMEAR-type stations in Finland (SMEAR-I-II-II-IV stations), in Estonia (SMEAR-Järviselja) and in China (SMEAR-Nanjing) and selected stations in Russia and ecosystem station network in China. PEEX observation network will fill in the current observational gap in the Siberian region and bring the Siberian observation setup into international context with the with standardized or

PDB Editor: a user-friendly Java-based Protein Data Bank file editor with a GUI.

PubMed

Lee, Jonas; Kim, Sung Hou

2009-04-01

The Protein Data Bank file format is the format most widely used by protein crystallographers and biologists to disseminate and manipulate protein structures. Despite this, there are few user-friendly software packages available to efficiently edit and extract raw information from PDB files. This limitation often leads to many protein crystallographers wasting significant time manually editing PDB files. PDB Editor, written in Java Swing GUI, allows the user to selectively search, select, extract and edit information in parallel. Furthermore, the program is a stand-alone application written in Java which frees users from the hassles associated with platform/operating system-dependent installation and usage. PDB Editor can be downloaded from http://sourceforge.net/projects/pdbeditorjl/.

Panning artifacts in digital pathology images

NASA Astrophysics Data System (ADS)

Avanaki, Ali R. N.; Lanciault, Christian; Espig, Kathryn S.; Xthona, Albert; Kimpe, Tom R. L.

2017-03-01

In making a pathologic diagnosis, a pathologist uses cognitive processes: perception, attention, memory, and search (Pena and Andrade-Filho, 2009). Typically, this involves focus while panning from one region of a slide to another, using either a microscope in a traditional workflow or software program and display in a digital pathology workflow (DICOM Standard Committee, 2010). We theorize that during panning operation, the pathologist receives information important to diagnosis efficiency and/or correctness. As compared to an optical microscope, panning in a digital pathology image involves some visual artifacts due to the following: (i) the frame rate is finite; (ii) time varying visual signals are reconstructed using imperfect zero-order hold. Specifically, after pixel's digital drive is changed, it takes time for a pixel to emit the expected amount of light. Previous work suggests that 49% of navigation is conducted in low-power/overview with digital pathology (Molin et al., 2015), but the influence of display factors has not been measured. We conducted a reader study to establish a relationship between display frame rate, panel response time, and threshold panning speed (above which the artifacts become noticeable). Our results suggest visual tasks that involve tissue structure are more impacted by the simulated panning artifacts than those that only involve color (e.g., staining intensity estimation), and that the panning artifacts versus normalized panning speed has a peak behavior which is surprising and may change for a diagnostic task. This is work in progress and our final findings should be considered in designing future digital pathology systems.

Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities.

PubMed

Sen, Dilara; Keung, Albert J

2018-01-01

The advent of locus-specific protein recruitment technologies has enabled a new class of studies in chromatin biology. Epigenome editors enable biochemical modifications of chromatin at almost any specific endogenous locus. Their locus specificity unlocks unique information including the functional roles of distinct modifications at specific genomic loci. Given the growing interest in using these tools for biological and translational studies, there are many specific design considerations depending on the scientific question or clinical need. Here we present and discuss important design considerations and challenges regarding the biochemical and locus specificities of epigenome editors. These include how to account for the complex biochemical diversity of chromatin; control for potential interdependency of epigenome editors and their resultant modifications; avoid sequestration effects; quantify the locus specificity of epigenome editors; and improve locus specificity by considering concentration, affinity, avidity, and sequestration effects.

Letter to the Editor

NASA Astrophysics Data System (ADS)

2000-01-01

All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Looking back on Physics Peter Gill Lecturer in Education, School of Education, King's College London, Franklin-Wilkins Building, Waterloo Road, London SE1 8WA

Makgadikgadi Salt Pan, Botswana, Africa

NASA Image and Video Library

1992-01-19

STS054-151-015 (13-19 Jan 1993) --- The Makgadikgadi Salt Pan is one of the largest features in Botswana visible from space. Any water that spills out of the Okavango Swamplands flows down to the Makgadikgadi where it evaporates. An ancient beach line can be seen as a smooth line around the west (left) side of the Pan. Orapa diamond mine can be detected due south of the pan as a small rectangle. The large geological feature known as the Great Dike of Zimbabwe can be seen far right. This large panorama shows clouds in southern Angola, Zambia and Zimbabwe in the distance.

EDITORIAL: Editor's Farewell

NASA Astrophysics Data System (ADS)

Hudson, R. P.

1989-01-01

The completion of Volume 26, 1989, marked the end of my tenure as Editor of Metrologia. My association with the journal, its parent body the Comité International des Poids et Mesures, its host organization the Bureau International des Poids et Mesures, the publishers Springer-Verlag and last (but by no means least) the Editorial Board, has been a pleasant one and I trust that the subscribers will have found the product to be generally satisfactory. There have been, it is true, some disappointments along the way and I shall mention two of these while expressing the hope that the new Editor will enjoy a greater success in their regard. First is the question of circulation, which has stayed dangerously low, although the shrinkage has tapered off in the most recent years. Because of the narrow public support, the costs of production are relatively high and this, through a consequently high subscription rate, tends to enshrine the unsatisfactory state of affairs. Modest schemes to broaden the journal's appeal and bring in a wider readership have foundered upon the first step, namely, that of procuring from staff members of the national standards laboratories the hoped-for articles which would discuss the state of the art in delivering the highest-quality measurement services to the public. However, some very interesting and bolder schemes are presently under discussion. I had also hoped to leaven the journal's content a little by regularly appearing articles on the latest developments within the great national laboratories. But, as with technical review articles, it has proven very difficult to find the right authors who can also spare the time, and only a few laboratories have found it possible to collaborate. In taking my leave, it remains for me to thank all the contributors, referees and readers for their support, to express the hope of an ever brighter future for Metrologia and to wish to the new Editor, Dr D A Blackburn, a happy and successful tenure.

Peer reviews and the role of a journal editor

USDA-ARS?s Scientific Manuscript database

Obtaining peer reviews for manuscripts submitted to scientific journals is becoming increasingly difficult. Changes to the system are necessary, and editors must cultivate and maintain a solid base of reviewers to help evaluate journal submissions. This article outlines some steps editors can and sh...

The Lives and Hard Times of Magazine Editors in the Big Apple: A Report on the Society of Magazine Editors' Educators Seminar.

ERIC Educational Resources Information Center

English, John W.

This report chronicles the first Society of Magazine Editors' educators seminar, which was held in New York from May 13-17, 1974, and was attended by ten journalism faculty. The industry's concerns, as expressed through editors, are paper, printing, postage, people, and profit. The Magazine Publishers Association (MPA) seems mostly concerned with…

Pan masala advertisements are surrogate for tobacco products.

PubMed

Sushma, C; Sharang, C

2005-01-01

Pan masala is a comparatively recent habit in India and is marketed with and without tobacco. Advertisements of tobacco products have been banned in India since 1st May 2004. The advertisements of plain pan masala, which continue in Indian media, have been suspected to be surrogate for tobacco products bearing the same name. The study was carried out to assess whether these advertisements were for the intended product, or for tobacco products with same brand name. The programme of a popular television Hindi news channel was watched for a 24-h period. Programmes on the same channel and its English counterpart were watched on different days to assess whether the advertisements were repeated. The total duration of telecast of a popular brand of plain pan masala (Pan Parag) was multiplied by the rate charged by the channel to provide the cost of advertisement of this product. The total sale value of the company was multiplied by the proportion of usage of plain pan masala out of gutka plus pan masala habit as observed from a different study, to provide the annual sale value of plain pan masala product under reference. The annual sale value of plain Pan Parag was estimated to be Rs. 67.1 million. The annual cost of the advertisement of the same product on two television channels was estimated at Rs. 244.6 million. The advertisements of plain pan masala seen on Indian television are a surrogate for the tobacco products bearing the same name.

Pan Progress

NASA Image and Video Library

2007-01-18

Pan is seen in this color view as it sweeps through the Encke Gap with its attendant ringlets. As the lemon-shaped little moon orbits Saturn, it always keeps its long axis pointed along a line toward the planet

A scoping review of competencies for scientific editors of biomedical journals.

PubMed

Galipeau, James; Barbour, Virginia; Baskin, Patricia; Bell-Syer, Sally; Cobey, Kelly; Cumpston, Miranda; Deeks, Jon; Garner, Paul; MacLehose, Harriet; Shamseer, Larissa; Straus, Sharon; Tugwell, Peter; Wager, Elizabeth; Winker, Margaret; Moher, David

2016-02-02

Biomedical journals are the main route for disseminating the results of health-related research. Despite this, their editors operate largely without formal training or certification. To our knowledge, no body of literature systematically identifying core competencies for scientific editors of biomedical journals exists. Therefore, we aimed to conduct a scoping review to determine what is known on the competency requirements for scientific editors of biomedical journals. We searched the MEDLINE®, Cochrane Library, Embase®, CINAHL, PsycINFO, and ERIC databases (from inception to November 2014) and conducted a grey literature search for research and non-research articles with competency-related statements (i.e. competencies, knowledge, skills, behaviors, and tasks) pertaining to the role of scientific editors of peer-reviewed health-related journals. We also conducted an environmental scan, searched the results of a previous environmental scan, and searched the websites of existing networks, major biomedical journal publishers, and organizations that offer resources for editors. A total of 225 full-text publications were included, 25 of which were research articles. We extracted a total of 1,566 statements possibly related to core competencies for scientific editors of biomedical journals from these publications. We then collated overlapping or duplicate statements which produced a list of 203 unique statements. Finally, we grouped these statements into seven emergent themes: (1) dealing with authors, (2) dealing with peer reviewers, (3) journal publishing, (4) journal promotion, (5) editing, (6) ethics and integrity, and (7) qualities and characteristics of editors. To our knowledge, this scoping review is the first attempt to systematically identify possible competencies of editors. Limitations are that (1) we may not have captured all aspects of a biomedical editor's work in our searches, (2) removing redundant and overlapping items may have led to the

EDITORIAL: Incoming Editor-in-Chief Incoming Editor-in-Chief

NASA Astrophysics Data System (ADS)

Birch, David

2012-01-01

It is a pleasure and an honour for me to be taking over as Editor-in-Chief of Measurement Science and Technology. MST is well known across research communities worldwide as a leading journal in which to publish new techniques and instrumentation. It has gained this enviable position largely because of the excellent guidance of its Editorial Board and dedicated staff at Institute of Physics Publishing over many years. I want to highlight in particular the contribution of the outgoing Editor Peter Hauptmann, and other Editors before him, in making the journal truly international. We thank Peter immensely for all his hard work in leading the journal, having exceptionally served two terms, each of five years. I come into the post of Editor at a very interesting and challenging time for research. The global recession is leading to cuts in research funding in many countries, researchers and their outputs are coming under closer scrutiny than ever before, and more is being expected of them. Journals play a critical role in monitoring and maintaining research standards, but we should be careful not to assume that journal Impact Factor is the sole measure of research quality. Although expediency may sometimes demand it, Impact Factor, as practitioners know, is subject dependent. One of the great things about science and technology for me is its level playing field. The key point is still innovation no matter where the work is done or where it is published. MST has a long pedigree of being the natural home of the highest quality papers from leading researchers wishing to report novel instrumentation and techniques. 2013 will mark the 90th anniversary of MST and we look forward to celebrating in style its sustained success. I recall with pride the first paper I published in Journal of Physics E: Scientific Instruments (as MST was previously titled) back in 1977. The paper reported the design and application of an early fluorescence lifetime spectrometer that I had constructed

7 CFR 58.913 - Evaporators and vacuum pans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

7 CFR 58.913 - Evaporators and vacuum pans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

7 CFR 58.913 - Evaporators and vacuum pans.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

7 CFR 58.913 - Evaporators and vacuum pans.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

7 CFR 58.913 - Evaporators and vacuum pans.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Evaporators and vacuum pans. 58.913 Section 58.913....913 Evaporators and vacuum pans. All equipment used in the removal of moisture from milk or milk... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. ...

Overview of ATLAS PanDA Workload Management

NASA Astrophysics Data System (ADS)

Maeno, T.; De, K.; Wenaus, T.; Nilsson, P.; Stewart, G. A.; Walker, R.; Stradling, A.; Caballero, J.; Potekhin, M.; Smith, D.; ATLAS Collaboration

2011-12-01

The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in addition to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.

Overview of ATLAS PanDA Workload Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maeno T.; De K.; Wenaus T.

2011-01-01

The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in additionmore » to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.« less

From the Board of Editors: on Plagiarism

NASA Astrophysics Data System (ADS)

2005-04-01

From the Board of Editors: on Plagiarism

Quantifying the effect of editor-author relations on manuscript handling times.

PubMed

Sarigöl, Emre; Garcia, David; Scholtes, Ingo; Schweitzer, Frank

2017-01-01

In this article we study to what extent the academic peer review process is influenced by social relations between the authors of a manuscript and the editor handling the manuscript. Taking the open access journal PlosOne as a case study, our analysis is based on a data set of more than 100,000 articles published between 2007 and 2015. Using available data on handling editor, submission and acceptance time of manuscripts, we study the question whether co-authorship relations between authors and the handling editor affect the manuscript handling time , i.e. the time taken between the submission and acceptance of a manuscript. Our analysis reveals (1) that editors handle papers co-authored by previous collaborators significantly more often than expected at random, and (2) that such prior co-author relations are significantly related to faster manuscript handling. Addressing the question whether these shorter manuscript handling times can be explained by the quality of publications, we study the number of citations and downloads which accepted papers eventually accumulate. Moreover, we consider the influence of additional (social) factors, such as the editor's experience, the topical similarity between authors and editors, as well as reciprocal citation relations between authors and editors. Our findings show that, even when correcting for other factors like time, experience, and performance, prior co-authorship relations have a large and significant influence on manuscript handling times, speeding up the editorial decision on average by 19 days.

EDITORIAL: Editor's Introduction

NASA Astrophysics Data System (ADS)

Blackburn, D. A.

1990-01-01

Since its first issue in 1965 Metrologia has had just three editors, a history of tenure which suggests that those who hold the post find in it sufficient to interest, occupy, challenge and amuse them. I see no reason to doubt that this happy circumstance will continue and look forward to my own period as editor with the intention of retaining, insofar as I am able to interpret them, the best traditions the journal has established so far. As I take up my editorial duties I have become aware that surrounding Metrologia there is a small community of authors, reviewers and readers on whose support the success of the journal entirely depends. It is a community in which the roles change daily with some of its members engaged, even simultaneously, as reader, reviewer and author. I am well aware that the goodwill extended to me as I enter this community is in no small part due the efforts of the outgoing editor, Dr Ralph Hudson, whose easy, engaging and courteous, yet firm, relationship with authors and reviewers emerges clearly from editorial correspondence. I thank him for that he has done and wish him an active and happy retirement. A short foray into the records of Metrologia shows - in the first editorial - that four main kinds of article were originally envisaged: research articles likely to contribute to progress in fundamental scientific measurements, reports of experiments or techniques of particular importance or originality in the area of secondary measurement, articles concerning the decisions of the Comité International des Poids et Mesures, and review articles. No balance was specified but a priority was assigned to articles dealing with fundamental metrology. Of the four categories, the first two represent the core of Metrologia's activity and largely determine its reputation as a publication. For this reason, editorial implementation of the policy set by the CIPM is mainly exercised through the operation of a reviewing system which is intentionally strict

Editorial independence at medical journals owned by professional associations: a survey of editors.

PubMed

Davis, Ronald M; Müllner, Marcus

2002-10-01

The purpose of this study was to assess the degree of editorial independence at a sample of medical journals and the relationship between the journals and their owners. We surveyed the editors of 33 medical journals owned by not-for-profit organizations ("associations"), including 10 journals represented on the International Committee of Medical Journal Editors (nine of which are general medical journals) and a random sample of 23 specialist journals with high impact factors that are indexed by the Institute for Scientific Information. The main outcome measures were the authority to hire, fire, and oversee the work of the editor; the editor's tenure and financial compensation; control of the journal's budget; publication of material about the association; and the editor's perceptions about editorial independence and pressure over editorial content. Of the 33 editors, 23 (70%) reported having complete editorial freedom, and the remainder reported a high level of freedom (a score of > or = 8, where 10 equals complete editorial freedom and 1 equals no editorial freedom). Nevertheless, a substantial minority of editors reported having received at least some pressure in recent years over editorial content from the association's leadership (42%), senior staff (30%), or rank-and-file members (39%). The association's board of directors has the authority to hire (48%) or fire (55%) the editor for about half of the journals, and the editor reports to the board for 10 journals (30%). Twenty-three editors (70%) are appointed for a specific term (median term = 5 years). Three-fifths of the journals have no control over their profit, and the majority of journals use the association's legal counsel and/or media relations staff. Stronger safeguards are needed to give editors protection against pressure over editorial content, including written guarantees of editorial freedom and governance structures that support those guarantees. Strong safeguards are also needed because editors

49 CFR 230.69 - Ash pans.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Ash pans. 230.69 Section 230.69 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders Ash Pans § 230...

Student-Centered Designs of Pan-African Literature Courses

ERIC Educational Resources Information Center

M'Baye, Babacar

2010-01-01

A student-centered teaching methodology is an essential ingredient of a successful Pan-African literary course. In this article, the author defines Pan-Africanism and how to go about designing a Pan-African literature course. The author combines reading assignments with journals, film presentations, and lectures in a productive learning…

Vaccination to conserved influenza antigens in mice using a novel Simian adenovirus vector, PanAd3, derived from the bonobo Pan paniscus.

PubMed

Vitelli, Alessandra; Quirion, Mary R; Lo, Chia-Yun; Misplon, Julia A; Grabowska, Agnieszka K; Pierantoni, Angiolo; Ammendola, Virginia; Price, Graeme E; Soboleski, Mark R; Cortese, Riccardo; Colloca, Stefano; Nicosia, Alfredo; Epstein, Suzanne L

2013-01-01

Among approximately 1000 adenoviruses from chimpanzees and bonobos studied recently, the Pan Adenovirus type 3 (PanAd3, isolated from a bonobo, Pan paniscus) has one of the best profiles for a vaccine vector, combining potent transgene immunogenicity with minimal pre-existing immunity in the human population. In this study, we inserted into a replication defective PanAd3 a transgene expressing a fusion protein of conserved influenza antigens nucleoprotein (NP) and matrix 1 (M1). We then studied antibody and T cell responses as well as protection from challenge infection in a mouse model. A single intranasal administration of PanAd3-NPM1 vaccine induced strong antibody and T cell responses, and protected against high dose lethal influenza virus challenge. Thus PanAd3 is a promising candidate vector for vaccines, including universal influenza vaccines.

EDITORIAL: Message from the Editor Message from the Editor

NASA Astrophysics Data System (ADS)

Thomas, Paul

2011-01-01

As usual, being an even year, the 23rd IAEA Fusion Energy Conference took place at Daejeon, Korea. The event was notable not just for the quality of the presentations but also for the spectacular opening ceremony, in the presence of the Prime Minister, Kim Hwang-sik. The Prime Minister affirmed the importance of research into fusion energy research and pledged support for ITER. Such political visibility is good news, of course, but it brings with it the obligation to perform. Fortunately, good performance was much in evidence in the papers presented at the conference, of which a significant proportion contain 'ITER' in the title. Given this importance of ITER and the undertaking by the Nuclear Fusion journal to publish papers associated with Fusion Energy Conference presentations, the Nuclear Fusion Editorial Board has decided to adopt a simplified journal scope that encompasses technology papers more naturally. The scope is available from http://iopscience.iop.org/0029-5515/page/Journal%20information but is reproduced here for clarity: Nuclear Fusion publishes articles making significant advances to the field of controlled thermonuclear fusion. The journal scope includes: the production, heating and confinement of high temperature plasmas; the physical properties of such plasmas; the experimental or theoretical methods of exploring or explaining them; fusion reactor physics; reactor concepts; fusion technologies. The key to scope acceptability is now '....significant advances....' rather than any particular area of controlled thermonuclear fusion research. It is hoped that this will make scope decisions easier for the Nuclear Fusion office, the referees and the Editor.The Nuclear Fusion journal has continued to make an important contribution to the research programme and has maintained its position as the leading journal in the field. This is underlined by the fact that Nuclear Fusion has received an impact factor of 4.270, as listed in ISI's 2009 Science Citation

The Pan-STARRS1 Surveys

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.

2014-01-01

Pan-STARRS1 is approaching the completion of the PS1 Science Mission. Operations of the PS1 System include the Observatory, Telescope, 1.4 Gigapixel Camera, Image Processing Pipeline , PSPS relational database and reduced science product software servers. The Pan-STARRS1 Surveys include: (1) A 3pi Steradian Survey, (2) A Medium Deep survey of 10 PS1 footprints spaced around the sky; (3) A solar system survey optimized for Near Earth Objects, (4) a Stellar Transit Survey; and (5) a Deep Survey of M31. The PS1 3pi Survey has now covered the sky north of dec=-30 with more than 12 visits in five bands: g,r,i,z and y or over ~60 epochs per 0.25 arcsec resolution element on the sky. The performance of the PS1 system, sky coverage, cadence, and data quality of the Pan-STARRS1 Surveys will be presented as well as progress in reprocessing of the data taken to date and the plans for the public release of all Pan-STARRS1 data products in the spring of 2015. The Pan-STARRS1 Surveys (PS1) have been made possible through contributions of the Institute for Astronomy, the University of Hawaii, the Pan-STARRS Project Office, the Max-Planck Society and its participating institutes, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching, The Johns Hopkins University, Durham University, the University of Edinburgh, Queen's University Belfast, the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated, the National Central University of Taiwan, the Space Telescope Science Institute, the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued through the Planetary Science Division of the NASA Science Mission Directorate, the National Science Foundation under Grant No. AST-1238877, the University of Maryland, and Eotvos Lorand University (ELTE).

SIRE: A Simple Interactive Rule Editor for NICBES

NASA Technical Reports Server (NTRS)

Bykat, Alex

1988-01-01

To support evolution of domain expertise, and its representation in an expert system knowledge base, a user-friendly rule base editor is mandatory. The Nickel Cadmium Battery Expert System (NICBES), a prototype of an expert system for the Hubble Space Telescope power storage management system, does not provide such an editor. In the following, a description of a Simple Interactive Rule Base Editor (SIRE) for NICBES is described. The SIRE provides a consistent internal representation of the NICBES knowledge base. It supports knowledge presentation and provides a user-friendly and code language independent medium for rule addition and modification. The SIRE is integrated with NICBES via an interface module. This module provides translation of the internal representation to Prolog-type rules (Horn clauses), latter rule assertion, and a simple mechanism for rule selection for its Prolog inference engine.

Kamide reflects on JGR and the role of editor

NASA Astrophysics Data System (ADS)

Woods, Peter

After serving the space physics community for more than 11 years, Y. Kamide of the Solar-Terrestrial Environment Laboratory at Nagoya University in Toyokawa, Japan, retired as editor of the Journal of Geophysical Research-Space Physics for the Asian/Pacific region. He had been a JGR editor since AGU first opened two editorial offices in Europe and the Asian/Pacific region in 1989. Even as the initial JGR editor in Asia, Kamide was not new to AGU editorial business. Before accepting the JGR position, Kamide served 3 years as the editor in Japan for Geophysical Research Letters.According to Kamide, over the last 5 years, the number of high-quality submissions to JGR in the Asian/Pacific region has increased dramatically, by a factor of 2.5. This increase came mostly from the younger generation of scientists, which bodes well for the future of JGR and space physics in general. Together with the substantial contributions to JGR from the European community, this achievement has been recognized by AGU as proof that JGR is truly an international journal of the highest editorial standards.

Adsorption Isotherms for Xenon and Krypton using INL HZ-PAN and AgZ-PAN Sorbents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garn, Troy G.; Greenhalgh, Mitchell; Rutledge, Veronica J.

2014-08-01

The generation of adsorption isotherms compliments the scale-up of off-gas processes used to control the emission of encapsulated radioactive volatile fission and activation products released during Used Nuclear Fuel (UNF) reprocessing activities. A series of experiments were conducted to obtain capacity results for varying Kr and Xe gas concentrations using HZ-PAN and AgZ-PAN engineered form sorbents. Gas compositions for Kr ranged from 150-40,000 ppmv and 250-5020 ppmv for Xe in a helium balance. The experiments were all performed at 220 K at a flowrate of 50 sccm. Acquired capacities were then respectively fit to the Langmuir equation using the Langmuirmore » linear regression method to obtain the equilibrium parameters Qmax and Keq. Generated experimental adsorption isotherms were then plotted with the Langmuir predicted isotherms to illustrate agreement between the two. The Langmuir parameters were provided for input into the OSPREY model to predict breakthrough of single component adsorption of Kr and Xe on HZ-PAN and AgZ-PAN sorbents at the experimental conditions tested. Kr and Xe capacities resulting from model breakthrough predictions were then compared to experimental capacities for model validation.« less

Letters to the Editor

NASA Astrophysics Data System (ADS)

1997-07-01

All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Joining capacitors R Bridges King Edward's School, Birmingham B15 2UA, UK Enjoying Physics John Bausor 5 Longcrofte Road, Edgware, Middlesex HA8 6RR, UK The disadvantages of success M L Cooper Newham College of Further Education, London

Authors and editors assort on gender and geography in high-rank ecological publications

PubMed Central

Belou, Rebecca M.

2018-01-01

Peer-reviewed publication volume and caliber are widely-recognized proxies for academic merit, and a strong publication record is essential for academic success and advancement. However, recent work suggests that publication productivity for particular author groups may also be determined in part by implicit biases lurking in the publication pipeline. Here, we explore patterns of gender, geography, and institutional rank among authors, editorial board members, and handling editors in high-impact ecological publications during 2015 and 2016. A higher proportion of lead authors had female first names (33.9%) than editorial board members (28.9%), and the proportion of female first names among handling editors was even lower (21.1%). Female editors disproportionately edited publications with female lead authors (40.3% of publications with female lead authors were handled by female editors, though female editors handled only 34.4% of all studied publications). Additionally, ecological authors and editors were overwhelmingly from countries in the G8, and high-ranking academic institutions accounted for a large portion of both the published work, and its editorship. Editors and lead authors with female names were typically affiliated with higher-ranking institutions than their male peers. This description of author and editor features provides a baseline for benchmarking future trends in the ecological publishing culture. PMID:29420647

Authors and editors assort on gender and geography in high-rank ecological publications.

PubMed

Manlove, Kezia R; Belou, Rebecca M

2018-01-01

Peer-reviewed publication volume and caliber are widely-recognized proxies for academic merit, and a strong publication record is essential for academic success and advancement. However, recent work suggests that publication productivity for particular author groups may also be determined in part by implicit biases lurking in the publication pipeline. Here, we explore patterns of gender, geography, and institutional rank among authors, editorial board members, and handling editors in high-impact ecological publications during 2015 and 2016. A higher proportion of lead authors had female first names (33.9%) than editorial board members (28.9%), and the proportion of female first names among handling editors was even lower (21.1%). Female editors disproportionately edited publications with female lead authors (40.3% of publications with female lead authors were handled by female editors, though female editors handled only 34.4% of all studied publications). Additionally, ecological authors and editors were overwhelmingly from countries in the G8, and high-ranking academic institutions accounted for a large portion of both the published work, and its editorship. Editors and lead authors with female names were typically affiliated with higher-ranking institutions than their male peers. This description of author and editor features provides a baseline for benchmarking future trends in the ecological publishing culture.

Area-to-point regression kriging for pan-sharpening

NASA Astrophysics Data System (ADS)

Wang, Qunming; Shi, Wenzhong; Atkinson, Peter M.

2016-04-01

Pan-sharpening is a technique to combine the fine spatial resolution panchromatic (PAN) band with the coarse spatial resolution multispectral bands of the same satellite to create a fine spatial resolution multispectral image. In this paper, area-to-point regression kriging (ATPRK) is proposed for pan-sharpening. ATPRK considers the PAN band as the covariate. Moreover, ATPRK is extended with a local approach, called adaptive ATPRK (AATPRK), which fits a regression model using a local, non-stationary scheme such that the regression coefficients change across the image. The two geostatistical approaches, ATPRK and AATPRK, were compared to the 13 state-of-the-art pan-sharpening approaches summarized in Vivone et al. (2015) in experiments on three separate datasets. ATPRK and AATPRK produced more accurate pan-sharpened images than the 13 benchmark algorithms in all three experiments. Unlike the benchmark algorithms, the two geostatistical solutions precisely preserved the spectral properties of the original coarse data. Furthermore, ATPRK can be enhanced by a local scheme in AATRPK, in cases where the residuals from a global regression model are such that their spatial character varies locally.

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses.

PubMed

Holtsberg, Frederick W; Shulenin, Sergey; Vu, Hong; Howell, Katie A; Patel, Sonal J; Gunn, Bronwyn; Karim, Marcus; Lai, Jonathan R; Frei, Julia C; Nyakatura, Elisabeth K; Zeitlin, Larry; Douglas, Robin; Fusco, Marnie L; Froude, Jeffrey W; Saphire, Erica Ollmann; Herbert, Andrew S; Wirchnianski, Ariel S; Lear-Rooney, Calli M; Alter, Galit; Dye, John M; Glass, Pamela J; Warfield, Kelly L; Aman, M Javad

2016-01-01

The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses. Monoclonal antibody (MAb) cocktails have shown great potential as EVD therapeutics; however, the existing protective MAbs are virus species specific. Here we report the development of pan-ebolavirus and pan-filovirus antibodies generated by repeated immunization of mice with filovirus glycoproteins engineered to drive the B cell responses toward conserved epitopes. Multiple pan-ebolavirus antibodies were identified that react to the Ebola, Sudan, Bundibugyo, and Reston viruses. A pan-filovirus antibody that was reactive to the receptor binding regions of all filovirus glycoproteins was also identified. Significant postexposure efficacy of several MAbs, including a novel antibody cocktail, was demonstrated. For the first time, we report cross-neutralization and in vivo protection against two highly divergent filovirus species, i.e., Ebola virus and Sudan virus, with a single antibody. Competition studies indicate that this antibody targets a previously unrecognized conserved neutralizing epitope that involves the glycan cap. Mechanistic studies indicated that, besides neutralization, innate immune cell effector functions may play a role in the antiviral activity of the antibodies. Our findings further suggest critical novel epitopes that can be utilized to design effective cocktails for broad protection against multiple filovirus species. Filoviruses represent a major public health threat in Africa and an emerging global concern. Largely driven by the U.S. biodefense funding programs and reinforced by the 2014 outbreaks, current immunotherapeutics are primarily focused on a single filovirus species called Ebola virus (EBOV) (formerly Zaire Ebola virus). However, other filoviruses including Sudan, Bundibugyo, and Marburg viruses have caused human outbreaks with mortality rates as high as 90%. Thus, cross

Bi-cubic interpolation for shift-free pan-sharpening

NASA Astrophysics Data System (ADS)

Aiazzi, Bruno; Baronti, Stefano; Selva, Massimo; Alparone, Luciano

2013-12-01

Most of pan-sharpening techniques require the re-sampling of the multi-spectral (MS) image for matching the size of the panchromatic (Pan) image, before the geometric details of Pan are injected into the MS image. This operation is usually performed in a separable fashion by means of symmetric digital low-pass filtering kernels with odd lengths that utilize piecewise local polynomials, typically implementing linear or cubic interpolation functions. Conversely, constant, i.e. nearest-neighbour, and quadratic kernels, implementing zero and two degree polynomials, respectively, introduce shifts in the magnified images, that are sub-pixel in the case of interpolation by an even factor, as it is the most usual case. However, in standard satellite systems, the point spread functions (PSF) of the MS and Pan instruments are centered in the middle of each pixel. Hence, commercial MS and Pan data products, whose scale ratio is an even number, are relatively shifted by an odd number of half pixels. Filters of even lengths may be exploited to compensate the half-pixel shifts between the MS and Pan sampling grids. In this paper, it is shown that separable polynomial interpolations of odd degrees are feasible with linear-phase kernels of even lengths. The major benefit is that bi-cubic interpolation, which is known to represent the best trade-off between performances and computational complexity, can be applied to commercial MS + Pan datasets, without the need of performing a further half-pixel registration after interpolation, to align the expanded MS with the Pan image.

Handedness in captive bonobos (Pan paniscus).

PubMed

Harrison, Rebecca M; Nystrom, Pia

2008-01-01

Species level right-handedness is often considered to be unique to humans. Handedness is held to be interrelated to our language ability and has been used as a means of tracing the evolution of language. Here we examine handedness in 3 captive groups of bonobos (Pan paniscus) comprising 22 individuals. We found no evidence for species level handedness. Conclusions that can be drawn from these findings are: (1) species level handedness evolved after the divergence of the Pan and Homo lineages; (2) inconsistent preferences may represent precursors to human handedness, and (3) Pan may have language abilities but these cannot be measured using handedness. Copyright 2008 S. Karger AG, Basel.

Writing filter processes for the SAGA editor, appendix G

NASA Technical Reports Server (NTRS)

Kirslis, Peter A.

1985-01-01

The SAGA editor provides a mechanism by which separate processes can be invoked during an editing session to traverse portions of the parse tree being edited. These processes, termed filter processes, read, analyze, and possibly transform the parse tree, returning the result to the editor. By defining new commands with the editor's user defined command facility, which invoke filter processes, authors of filter can provide complex operations as simple commands. A tree plotter, pretty printer, and Pascal tree transformation program were already written using this facility. The filter processes are introduced, parse tree structure is described and the library interface made available to the programmer. Also discussed is how to compile and run filter processes. Examples are presented to illustrate aspect of each of these areas.

Editor's message: Student involvement

Treesearch

Bill Block

2012-01-01

In the initial Editor's Message of this volume, I stated my intent to involve more students in the publication process. A number of people commented on it being a good idea, but only a couple have followed up. One was Paul Krausman, President of The Wildlife Society. We matched graduate students from the University of Montana wildlife program with manuscripts...

Letters to the Editor

NASA Astrophysics Data System (ADS)

1997-03-01

All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Criticisms of hands-on pseudoscience David J Fisher 27 Elderberry Road, Cardiff CF5 3RG, UK Measuring varying fields Don Koks Adelaide University, Australia Relativity at A-level: a comment David Sang 3 Ellasdale Road, Bognor Regis, PO21 2SG, UK

14. RW Meyer Sugar Mill: 18761889. Sorghum Pan. Manufactured by ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. RW Meyer Sugar Mill: 1876-1889. Sorghum Pan. Manufactured by John Nott & Co., Honolulu, Hawaii, 1878. View: In the sorghum pan, heat was applied to the cane juice to clarify it, evaporate its water content, and concentrate the sugar crystals. The pan was set on a slope so that the juice would move through the compartments by gravity. The hand-lever sluice valves in the partition walls between the compartments permitted the sugar boiler to regulate the movement of batches of cane juice flowing through the pan. The metal fins projecting from the bottom of the pan imparted a circuitous route to the juice as it flowed through the pan--this made it flow over a much greater heated surface. The fins also supplemented the pan's heating surface by ... - R. W. Meyer Sugar Mill, State Route 47, Kualapuu, Maui County, HI

Generating the Field: The Role of Editors in Disciplinary Formation

ERIC Educational Resources Information Center

Selfe, Cynthia; Villanueva, Victor; Parks, Steve

2017-01-01

In the following conversation, conducted asynchronously through email, three current and former editors discuss the role of publishing in creating a disciplinary identity. Speaking from the academic (Villanueva), digital (Selfe), and community (Parks), and, often crossing these three categories, the editors discuss how the field has failed to…

Research Reporting Guidelines in Dentistry: A Survey of Editors.

PubMed

Sarkis-Onofre, Rafael; Cenci, Maximiliano Sérgio; Moher, David; Pereira-Cenci, Tatiana

2017-01-01

The use of reporting guidelines has an important role in the development of health research, improving the quality and precision of the publications. This study evaluated how dental journals use reporting guidelines. All editors of dental journals registered on the 2013 Journal Citation Reports list (n=81) were invited to participate. The data were collected by a self-reported web-based questionnaire. Information about the profile of journal/editor and on the use of reporting guidelines by journals was gathered. Information/recommendations about the use of reporting guidelines were collected from the websites of all journals. Data were descriptively analyzed and frequencies were summarized. Thirty-four (42%) editors completed the questionnaire. Most journals are members of Committee on Publication Ethics (64.7%) and/or follow the International Committee of Medical Journal Editors recommendations (20.6%), while 26.5% are not members of any editorial group. Most editors are unfamiliar with the EQUATOR Network (55.9%), do not work full time (85.3%) and 88.2% have some income/payment. Most of them received educational training for this position (55.9%). The CONSORT Statement was endorsed by 61.8% of journals. Information from websites showed that 44.4% journals do not recommend any reporting guideline, 51.9% mention CONSORT Statement in the website and 28.4% only recommend the use of CONSORT Statement. There is clearly room for improving the use of reporting guidelines in dental journals. Broadening the understanding and the endorsement/adherence/implementation of reporting guidelines by journals may promote quality and transparence of published dental research.

From the Board of Editors: on Plagiarism

NASA Astrophysics Data System (ADS)

2005-03-01

Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially similar scientific content

7 CFR 58.217 - Evaporators and/or vacuum pans.

Code of Federal Regulations, 2011 CFR

2011-01-01

....217 Evaporators and/or vacuum pans. Evaporators or vacuum pans or both, with open type condensers shall be equipped with an automatic condenser water level control, barometric leg, or so constructed so... Sanitary Standards for Milk and Milk Products Evaporators and Vacuum Pans. When enclosed type condensers...

Multi-Column Xe/Kr Separation with AgZ-PAN and HZ-PAN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenhalgh, Mitchell Randy; Garn, Troy Gerry; Welty, Amy Keil

Previous multi-column xenon/krypton separation tests have demonstrated the capability of separating xenon from krypton in a mixed gas feed stream. The results of this initial testing with AgZ-PAN and HZ-PAN indicated that an excellent separation of xenon from krypton could be achieved. Building upon these initial results, a series of additional multi-column testing were performed in FY-16. The purpose of this testing was to scale up the sorbent beds, test a different composition of feed gas and attempt to improve the accuracy of the analysis of the individual capture columns’ compositions. Two Stirling coolers were installed in series to performmore » this testing. The use of the coolers instead of the cryostat provided two desired improvements, 1) removal of the large dilution due to the internal volume of the cryostat adsorption chamber, and 2) ability to increase the sorbent bed size for scale-up. The AgZ-PAN sorbent, due to its xenon selectivity, was loaded in the first column to capture the xenon while allowing the krypton to flow through and be routed to a second column containing the HZ-PAN for capture and analysis. The gases captured on both columns were sampled with evacuated sample bombs and subsequently analyzed via GC-MS for both krypton and xenon. The results of these tests can be used to develop the scope of future testing and analysis using this test bed for demonstrating the capture and separation of xenon and krypton using sorbents, for demonstrating desorption and regeneration of the sorbents, and for determining compositions of the desorbed gases. They indicate a need for future desorption studies in order to better quantify co-adsorbed species and final krypton purity.« less

EDITORIAL: Editorial from the new Editor-in-Chief for 2014 Editorial from the new Editor-in-Chief for 2014

NASA Astrophysics Data System (ADS)

Graham, W. G.

2014-02-01

I am honoured to take on the leadership of Plasma Sources Science and Technology (PSST) as the successor to Professor Mark J Kushner, with whom I have had the pleasure to work on the journal for many years. Under Mark's insightful and energetic leadership over the last six years, PSST has cemented its position as the journal of choice within its subject area and is now one of the most successful journals in the field. In this first issue of 2014, I would like to reflect on some of the events and achievements of 2013. At the start of the year the PSST Editorial Board, recognizing the vital importance of atomic, molecular and optical (AMO) data to low-temperature plasma physics, agreed that PSST would accept papers reporting such new data, generated through both experiment and theory. Jonathan Tennyson joined the Editorial Board to represent this area. In March Anne Bourdon joined the Associate Editor team and has since then played a key part in the journal's review process alongside our other Editors. During the autumn, PSST moved to a new editorial management system. In December Deborah O'Connell was awarded the 2013 Hershkowitz Early Career Award and Review and joins the Editorial Board as of 2014. I would also like to thank Miles Turner for his work in leading the drafting of a guide on the details necessary in the reporting of the results of computer simulations; the main conclusions of this report have been incorporated into the journal policy. Overall 2013 has been another successful year for PSST; paper submissions were up by 8% on the previous year and there was the highest ever number of downloads of PSST papers in one year. Another noteworthy feature of 2013 was the continuing improvement in publication times while maintaining our high standards for acceptance and providing expert feedback coupled with encouragement particularly to younger researchers and groups. Largely as a result of the hard work of our referees and Associate Editors, the average time

Preparing Students To Work on Newspaper Copy Desks: Are Educators Meeting Editors' Expectations?

ERIC Educational Resources Information Center

Auman, Ann E.; Cook, Betsy B.

A study surveyed two groups in the fall of 1994, journalism educators and newspaper editors. Educators completed a survey regarding the course content and skill areas emphasized in beginning level copy editing courses, while editors were asked to respond to questions regarding the skills they expect entry-level copy editors to have. Respondents…

Newspaper Ethics and Managing Editors: The Evolution of APME's Code.

ERIC Educational Resources Information Center

De Mott, John

A review of the 42-year development of the professional code of ethics of the Associated Press Managing Editors (APME) demonstrates an effort to elevate newspaper ethical standards around the country. Following the example of the American Society of Newspaper Editors in establishing its "Canons of Journalism" in 1923, the APME formed a…

The Introductory Psychology Textbook Market: Perceptions of Authors and Editors.

ERIC Educational Resources Information Center

Griggs, Richard A.; Jackson, Sherri L.

1989-01-01

Surveys psychology textbook authors and editors on their perceptions of the introductory psychology textbook market. Finds that the textbook market is divided into three levels according to quality, and that authors and editors are not familiar with most textbooks. Notes that the growth of used book companies has adversely affected the market.…

Greetings from the new Editor-in-Chief, Ronald Stambaugh Greetings from the new Editor-in-Chief, Ronald Stambaugh

NASA Astrophysics Data System (ADS)

Stambaugh, Ronald

2012-04-01

I am very pleased to join the outstanding leadership team for the journal Nuclear Fusion as Scientific Editor. The journal's high position in the field of fusion energy research derives in no small measure from the efforts of the IAEA team in Vienna, the production and marketing of IOP Publishing, the Board of Editors led by its chairman Mitsuru Kikuchi, the Associate Editor for Inertial Confinement Max Tabak and the outgoing Scientific Editor, Paul Thomas. During Paul's five year tenure submissions have grown by over 40%. The usage of the electronic journal has grown year by year with about 300 000 full text downloads of Nuclear Fusion articles in 2011, an impressive figure due in part to the launch of the full 50 year archive. High quality has been maintained while times for peer review and publishing have been reduced and the journal achieved some of the highest impact factors ever (as high as 4.27). The journal has contributed greatly to building the international scientific basis for fusion. I was privileged to serve from 2003 to 2010 as chairman of the Coordinating Committee for the International Tokamak Physics Activity (ITPA) which published in Nuclear Fusion the first ITER Physics Basis (1999) and its later update (2007). The scientific basis that has been developed to date for fusion has led to the construction of major facilities to demonstrate the production of power-plant relevant levels of fusion reactions. We look forward to the journal continuing to play a key role in the international effort toward fusion energy as these exciting major facilities and the various approaches to fusion continue to be developed. It is clear that Nuclear Fusion maintains its position in the field because of the perceived high quality of the submissions, the refereeing and the editorial processes, and the availability and utility of the online journal. The creation of the Nuclear Fusion Prize, led by the Board of Editors chairman Mitsuru Kikuchi, for the most outstanding

Pan Air Geometry Management System (PAGMS): A data-base management system for PAN AIR geometry data

NASA Technical Reports Server (NTRS)

Hall, J. F.

1981-01-01

A data-base management system called PAGMS was developed to facilitate the data transfer in applications computer programs that create, modify, plot or otherwise manipulate PAN AIR type geometry data in preparation for input to the PAN AIR system of computer programs. PAGMS is composed of a series of FORTRAN callable subroutines which can be accessed directly from applications programs. Currently only a NOS version of PAGMS has been developed.

Pan and Waves

NASA Image and Video Library

2013-07-08

The shepherd moon Pan orbits Saturn in the Encke gap while the A ring surrounding the gap displays wave features created by interactions between the ring particles and Saturnian moons in this image from NASA Cassini spacecraft.

Editor and authors' psychology and the chance of teaching.

PubMed

Grammaticos, Philip C

2006-01-01

It is the duty of the editor to communicate with the authors who submit their scientific work for publication. The question arises as to the best way to perform this communication. The goal is to publish papers that would make their authors proud and the readers of the journal, satisfied. This goal is expressed with honesty, kindness, politeness, diplomacy and when the editor communicated with authors from other Countries, the advice of a person familiar with the traditions of these Countries may be welcome. The unpleasant editor's duty to inform the authors of their paper being rejected, can be expressed either by writing a brief straight forward letter or by giving a more detailed answer or finally, by explaining to the authors their errors in a detailed manner, in other words, by giving them advice and consultation. In his reply to the authors whose paper has been rejected, the editor may touch a sensitive part of their behavior. Authors may consider their paper as "their intellectual child". Some times authors make unacceptable mistakes that may or may not be revealed by the reviewers. Explaining in detail errors and thus counseling the authors, is hard work for the editor but not always appreciated by the authors. The value of counseling and teaching has been emphasized even by ancient philosophers but nowadays enthusiasm in learning is sometimes lacking. Is there a solution to the above? Perhaps if "the instructions to authors" of a journal specified clearly the "submission terms" for accepting a paper for publication, then the authors could be self-evaluated and perhaps all parties concerned would be happier.

Core competencies for scientific editors of biomedical journals: consensus statement.

PubMed

Moher, David; Galipeau, James; Alam, Sabina; Barbour, Virginia; Bartolomeos, Kidist; Baskin, Patricia; Bell-Syer, Sally; Cobey, Kelly D; Chan, Leighton; Clark, Jocalyn; Deeks, Jonathan; Flanagin, Annette; Garner, Paul; Glenny, Anne-Marie; Groves, Trish; Gurusamy, Kurinchi; Habibzadeh, Farrokh; Jewell-Thomas, Stefanie; Kelsall, Diane; Lapeña, José Florencio; MacLehose, Harriet; Marusic, Ana; McKenzie, Joanne E; Shah, Jay; Shamseer, Larissa; Straus, Sharon; Tugwell, Peter; Wager, Elizabeth; Winker, Margaret; Zhaori, Getu

2017-09-11

Scientific editors are responsible for deciding which articles to publish in their journals. However, we have not found documentation of their required knowledge, skills, and characteristics, or the existence of any formal core competencies for this role. We describe the development of a minimum set of core competencies for scientific editors of biomedical journals. The 14 key core competencies are divided into three major areas, and each competency has a list of associated elements or descriptions of more specific knowledge, skills, and characteristics that contribute to its fulfillment. We believe that these core competencies are a baseline of the knowledge, skills, and characteristics needed to perform competently the duties of a scientific editor at a biomedical journal.

How Non-Daily Editors Describe Status and Function of Editorial Pages.

ERIC Educational Resources Information Center

Hynds, Ernest C.; Martin, Charles H.

1979-01-01

Results of a survey of 359 editors of nondaily newspapers indicates that most nondaily editors see their editorials and editorial pages as important segments of their newspapers and believe they can use them to help influence readers, particularly on local issues. (Author/GT)

Editorial Page Editors and Endorsements: Chain-owned vs. Independent Newspapers.

ERIC Educational Resources Information Center

St. Dizier, Byron

Questionnaires were sent to 114 of the 228 editorial page editors at newspapers in the United States with daily circulations greater than 50,000 for a study that compared (1) the editor-publisher relationship existing at chains to that found at independent papers, and (2) the 1984 presidential endorsements made by chains to those by independent…

Statement on Publication Ethics for Editors and Publishers.

PubMed

Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Gorin, Sergey V; Koroleva, Anna M; Kitas, George D

2016-09-01

The digitization and related developments in journal editing and publishing necessitate increasing the awareness of all stakeholders of science communication in the emerging global problems and possible solutions. Journal editors and publishers are frequently encountered with the fast-growing problems of authorship, conflicts of interest, peer review, research misconduct, unethical citations, and inappropriate journal impact metrics. While the number of erroneous and unethical research papers and wasteful, or 'predatory', journals is increasing exponentially, responsible editors are urged to 'clean' the literature by correcting or retracting related articles. Indexers are advised to implement measures for accepting truly influential and ethical journals and delisting sources with predatory publishing practices. Updating knowledge and skills of authors, editors and publishers, developing and endorsing recommendations of global editorial associations, and (re)drafting journal instructions can be viewed as potential tools for improving ethics of academic journals. The aim of this Statement is to increase awareness of all stakeholders of science communication of the emerging ethical issues in journal editing and publishing and initiate a campaign of upgrading and enforcing related journal instructions.

Statement on Publication Ethics for Editors and Publishers

PubMed Central

2016-01-01

The digitization and related developments in journal editing and publishing necessitate increasing the awareness of all stakeholders of science communication in the emerging global problems and possible solutions. Journal editors and publishers are frequently encountered with the fast-growing problems of authorship, conflicts of interest, peer review, research misconduct, unethical citations, and inappropriate journal impact metrics. While the number of erroneous and unethical research papers and wasteful, or 'predatory', journals is increasing exponentially, responsible editors are urged to 'clean' the literature by correcting or retracting related articles. Indexers are advised to implement measures for accepting truly influential and ethical journals and delisting sources with predatory publishing practices. Updating knowledge and skills of authors, editors and publishers, developing and endorsing recommendations of global editorial associations, and (re)drafting journal instructions can be viewed as potential tools for improving ethics of academic journals. The aim of this Statement is to increase awareness of all stakeholders of science communication of the emerging ethical issues in journal editing and publishing and initiate a campaign of upgrading and enforcing related journal instructions. PMID:27510376

R. E. (Ted) Munn — Founding editor; a mini-biography

NASA Astrophysics Data System (ADS)

Taylor, Peter; Thomas, Morley; Truhlar, Ed; Whelpdale, Doug

1996-02-01

Ted Munn founded Boundary-Layer Meteorology in 1970 and served as Editor for 75 volumes over a 25 year period. This short article briefly reviews Ted's scientific career with the Atmospheric Environment Service (of Canada), the International Institute for Applied Systems Analysis in Austria and with the Institute of Environmental Studies at the University of Toronto, and as editor of this journal.

3. RW Meyer Sugar Mill: 18761889. Sorghum pan and boiling ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. RW Meyer Sugar Mill: 1876-1889. Sorghum pan and boiling range flue. Manufactured by John Nott & Co., Honolulu, Hawaii, 1878. View: South side of sorghum pan and boiling range flue. In the sorghum pan heat was applied to the cane juice to clarify it, evaporate its water content, and concentrate the sugar crystals. Hot gasses moved through the flue underneath the entire copper bottom of the sorghum pan from the furnace (east) end to the smokestack (west) end of the boiling range. The sorghum pan sides are of redwood. The flue is built of fire-brick, masonry, and portland cement. - R. W. Meyer Sugar Mill, State Route 47, Kualapuu, Maui County, HI

Skeletal development in Pan paniscus with comparisons to Pan troglodytes.

PubMed

Bolter, Debra R; Zihlman, Adrienne L

2012-04-01

Fusion of skeletal elements provides markers for timing of growth and is one component of a chimpanzee's physical development. Epiphyseal closure defines bone growth and signals a mature skeleton. Most of what we know about timing of development in chimpanzees derives from dental studies on Pan troglodytes. Much less is known about the sister species, Pan paniscus, with few in captivity and a wild range restricted to central Africa. Here, we report on the timing of skeletal fusion for female captive P. paniscus (n = 5) whose known ages range from 0.83 to age 11.68 years. Observations on the skeletons were made after the individuals were dissected and bones cleaned. Comparisons with 10 female captive P. troglodytes confirm a generally uniform pattern in the sequence of skeletal fusion in the two captive species. We also compared the P. paniscus to a sample of three unknown-aged female wild P. paniscus, and 10 female wild P. troglodytes of known age from the Taï National Park, Côte d'Ivoire. The sequence of teeth emergence to bone fusion is generally consistent between the two species, with slight variations in late juvenile and subadult stages. The direct-age comparisons show that skeletal growth in captive P. paniscus is accelerated compared with both captive and wild P. troglodytes populations. The skeletal data combined with dental stages have implications for estimating the life stage of immature skeletal materials of wild P. paniscus and for more broadly comparing the skeletal growth rates among captive and wild chimpanzees (Pan), Homo sapiens, and fossil hominins. Copyright © 2012 Wiley Periodicals, Inc.

Ethical dilemmas in scientific publication: pitfalls and solutions for editors.

PubMed

Gollogly, Laragh; Momen, Hooman

2006-08-01

Editors of scientific journals need to be conversant with the mechanisms by which scientific misconduct is amplified by publication practices. This paper provides definitions, ways to document the extent of the problem, and examples of editorial attempts to counter fraud. Fabrication, falsification, duplication, ghost authorship, gift authorship, lack of ethics approval, non-disclosure, 'salami' publication, conflicts of interest, auto-citation, duplicate submission, duplicate publications, and plagiarism are common problems. Editorial misconduct includes failure to observe due process, undue delay in reaching decisions and communicating these to authors, inappropriate review procedures, and confounding a journal's content with its advertising or promotional potential. Editors also can be admonished by their peers for failure to investigate suspected misconduct, failure to retract when indicated, and failure to abide voluntarily by the six main sources of relevant international guidelines on research, its reporting and editorial practice. Editors are in a good position to promulgate reasonable standards of practice, and can start by using consensus guidelines on publication ethics to state explicitly how their journals function. Reviewers, editors, authors and readers all then have a better chance to understand, and abide by, the rules of publishing.

Transferable Output ASCII Data (TOAD) editor version 1.0 user's guide

NASA Technical Reports Server (NTRS)

Bingel, Bradford D.; Shea, Anne L.; Hofler, Alicia S.

1991-01-01

The Transferable Output ASCII Data (TOAD) editor is an interactive software tool for manipulating the contents of TOAD files. The TOAD editor is specifically designed to work with tabular data. Selected subsets of data may be displayed to the user's screen, sorted, exchanged, duplicated, removed, replaced, inserted, or transferred to and from external files. It also offers a number of useful features including on-line help, macros, a command history, an 'undo' option, variables, and a full compliment of mathematical functions and conversion factors. Written in ANSI FORTRAN 77 and completely self-contained, the TOAD editor is very portable and has already been installed on SUN, SGI/IRIS, and CONVEX hosts.

Line-Editor Computer Program

NASA Technical Reports Server (NTRS)

Scott, Peter J.

1989-01-01

ZED editing program for DEC VAX computer simple, powerful line editor for text, program source code, and nonbinary data. Excels in processing of text by use of procedure files. Also features versatile search qualifiers, global changes, conditionals, online help, hexadecimal mode, space compression, looping, logical combinations of search strings, journaling, visible control characters, and automatic detabbing. Users of Cambridge implementation devised such ZED procedures as chess games, calculators, and programs for evaluating pi. Written entirely in C.

From the Board of Editors: on Plagiarism

NASA Astrophysics Data System (ADS)

2005-04-01

Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially

From the Board of Editors: on Plagiarism

NASA Astrophysics Data System (ADS)

2005-05-01

Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially

29 CFR 793.11 - Combination announcer, news editor and chief engineer.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Combination announcer, news editor and chief engineer. 793...)(9) OF THE FAIR LABOR STANDARDS ACT Requirements for Exemption § 793.11 Combination announcer, news... as a news editor. In such cases, the primary employment test under the section 13(b)(9) exemption...

29 CFR 793.11 - Combination announcer, news editor and chief engineer.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Combination announcer, news editor and chief engineer. 793...)(9) OF THE FAIR LABOR STANDARDS ACT Requirements for Exemption § 793.11 Combination announcer, news... as a news editor. In such cases, the primary employment test under the section 13(b)(9) exemption...

29 CFR 793.11 - Combination announcer, news editor and chief engineer.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Combination announcer, news editor and chief engineer. 793...)(9) OF THE FAIR LABOR STANDARDS ACT Requirements for Exemption § 793.11 Combination announcer, news... as a news editor. In such cases, the primary employment test under the section 13(b)(9) exemption...

STARLSE -- Starlink Extensions to the VAX Language Sensitive Editor

NASA Astrophysics Data System (ADS)

Warren-Smith, R. F.

STARLSE is a ``Starlink Sensitive'' editor based on the VAX Language Sensitive Editor (LSE). It exploits the extensibility of LSE to provide additional features which assist in the writing of portable Fortran 77 software with a standard Starlink style. STARLSE is intended mainly for use by those writing ADAM applications and subroutine libraries for distribution as part of the Starlink Software Collection, although it may also be suitable for other software projects. It is designed to integrate with the SST (Simple Software Tools) package.

Microstructural characterization of PAN based carbon fiber reinforced nylon 6 polymer composites

NASA Astrophysics Data System (ADS)

Munirathnamma, L. M.; Ningaraju, S.; Kumar, K. V. Aneesh; Ravikumar, H. B.

2018-04-01

Microstructural characterization of nylon 6/polyacrolonitrile based carbon fibers (PAN-CFs) of 10 to 40 wt% has been performed by positron lifetime technique (PLT). The positron lifetime parameters viz., o-Ps lifetime (τ3), o-Ps intensity (I3) and fractional free volume (Fv) of nylon 6/PAN-CF composites are correlated with the mechanical properties viz., Tensile strength and Young's modulus. The Fv show negative deviation with the reinforcement of 10 to 40 wt% of PAN-CF from the linear additivity relation. The negative deviation in nylon 6/PAN-CF composite suggests the induced molecular packing due to the chemical interaction between the polymeric chains of nylon 6 and PAN-CF. This is evident from Fourier Transform Infrared Spectrometry (FTIR) studies. The FTIR results suggests that observed negative deviation in PALS results of nylon 6/PAN-CF reinforced polymer composites is due to the induced chemical interaction at N-H-O sites. The improved tensile strength (TS) and Young's modulus (YM) in nylon 6/PAN-CF reinforced polymer composites is due to AS4C (surface treated and epoxy coated) PAN-CF has shown highest adhesion level due to better stress transfer between nylon 6 and PAN-CF.

Thanks to outgoing Associate Editors

NASA Astrophysics Data System (ADS)

Lichti, Derek D.; Weng, Qihao

2018-04-01

As of the end of December 2017, Professors Eberhard Gülch, Olaf Hellwich, Minho Kim, and Lalit Kumar have retired as Associate Editors of the ISPRS Journal of Photogrammetry and Remote Sensing. Our Journal's readership has benefited greatly from their longstanding commitment to their editorial duties. Both Profs. Gülch and Hellwich began their service to the Journal in 2007, while Profs. Kumar and Kim began in 2012 and 2014, respectively. In their many years as editors, they have witnessed the incredible growth of the Journal in terms of the number of papers submitted and published as well as the impact factor. Thanks to their high standards for paper quality and rigorous peer review, these professors have been important contributors to the Journal's current high standing. They were very versatile in terms of the scope of papers they could handle. Eberhard handled papers in photogrammetry, terrain modelling and geographic information systems (GIS) while Olaf handled papers in radar, computer vision and GIS. Both Lalit and Minho handled papers in optical remote sensing. On behalf of the Journal and the International Society for Photogrammetry and Remote Sensing, we thank them for many years of dedicated service to the Journal.

Chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) quantify split solid objects.

PubMed

Cacchione, Trix; Hrubesch, Christine; Call, Josep

2013-01-01

Recent research suggests that gorillas' and orangutans' object representations survive cohesion violations (e.g., a split of a solid object into two halves), but that their processing of quantities may be affected by them. We assessed chimpanzees' (Pan troglodytes) and bonobos' (Pan paniscus) reactions to various fission events in the same series of action tasks modelled after infant studies previously run on gorillas and orangutans (Cacchione and Call in Cognition 116:193-203, 2010b). Results showed that all four non-human great ape species managed to quantify split objects but that their performance varied as a function of the non-cohesiveness produced in the splitting event. Spatial ambiguity and shape invariance had the greatest impact on apes' ability to represent and quantify objects. Further, we observed species differences with gorillas performing lower than other species. Finally, we detected a substantial age effect, with ape infants below 6 years of age being outperformed by both juvenile/adolescent and adult apes.

Letters to the Editor: Public Writing as a Response to Reading.

ERIC Educational Resources Information Center

Rinehammer, Nora

A study conducted by the copy editor of a small daily newspaper in Porter County, Indiana examines readers' motivations for writing letters to the editor. Analysis was based on letters that appeared in "The Vidette Messenger" September 16-30, 1992. Of 75 letters, 32 were responses to information published in the paper during the last 2…

The Pan-STARRS1 Small Area Survey 2

NASA Astrophysics Data System (ADS)

Metcalfe, N.; Farrow, D. J.; Cole, S.; Draper, P. W.; Norberg, P.; Burgett, W. S.; Chambers, K. C.; Denneau, L.; Flewelling, H.; Kaiser, N.; Kudritzki, R.; Magnier, E. A.; Morgan, J. S.; Price, P. A.; Sweeney, W.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.

2013-11-01

The Panoramic Survey Telescope and Rapid Response System 1 (Pan-STARRS1) survey is acquiring multi-epoch imaging in five bands (gP1, rP1, iP1, zP1, yP1) over the entire sky north of declination -30° (the 3π survey). In 2011 July a test area of about 70 deg2 was observed to the expected final depth of the main survey. In this, the first of a series of papers targeting the galaxy count and clustering properties of the combined multi-epoch test area data, we present a detailed investigation into the depth of the survey and the reliability of the Pan-STARRS1 analysis software. We show that the Pan-STARRS1 reduction software can recover the properties of fake sources, and show good agreement between the magnitudes measured by Pan-STARRS1 and those from Sloan Digital Sky Survey. We also examine the number of false detections apparent in the Pan-STARRS1 data. Our comparisons show that the test area survey is somewhat deeper than the Sloan Digital Sky Survey in all bands, and, in particular, the z band approaches the depth of the stacked Sloan Stripe 82 data.

Using TES retrievals to investigate PAN in North American biomass burning plumes

NASA Astrophysics Data System (ADS)

Fischer, Emily V.; Zhu, Liye; Payne, Vivienne H.; Worden, John R.; Jiang, Zhe; Kulawik, Susan S.; Brey, Steven; Hecobian, Arsineh; Gombos, Daniel; Cady-Pereira, Karen; Flocke, Frank

2018-04-01

Peroxyacyl nitrate (PAN) is a critical atmospheric reservoir for nitrogen oxide radicals, and plays a lead role in their redistribution in the troposphere. We analyze new Tropospheric Emission Spectrometer (TES) PAN observations over North America from July 2006 to July 2009. Using aircraft observations from the Colorado Front Range, we demonstrate that TES can be sensitive to elevated PAN in the boundary layer (˜ 750 hPa) even in the presence of clouds. In situ observations have shown that wildfire emissions can rapidly produce PAN, and PAN decomposition is an important component of ozone production in smoke plumes. We identify smoke-impacted TES PAN retrievals by co-location with NOAA Hazard Mapping System (HMS) smoke plumes. Depending on the year, 15-32 % of cases where elevated PAN is identified in TES observations (retrievals with degrees of freedom (DOF) > 0.6) overlap smoke plumes during July. Of all the retrievals attempted in the July 2006 to July 2009 study period, 18 % is associated with smoke . A case study of smoke transport in July 2007 illustrates that PAN enhancements associated with HMS smoke plumes can be connected to fire complexes, providing evidence that TES is sufficiently sensitive to measure elevated PAN several days downwind of major fires. Using a subset of retrievals with TES 510 hPa carbon monoxide (CO) > 150 ppbv, and multiple estimates of background PAN, we calculate enhancement ratios for tropospheric average PAN relative to CO in smoke-impacted retrievals. Most of the TES-based enhancement ratios fall within the range calculated from in situ measurements.

Correction of β-thalassemia mutant by base editor in human embryos.

PubMed

Liang, Puping; Ding, Chenhui; Sun, Hongwei; Xie, Xiaowei; Xu, Yanwen; Zhang, Xiya; Sun, Ying; Xiong, Yuanyan; Ma, Wenbin; Liu, Yongxiang; Wang, Yali; Fang, Jianpei; Liu, Dan; Songyang, Zhou; Zhou, Canquan; Huang, Junjiu

2017-11-01

β-Thalassemia is a global health issue, caused by mutations in the HBB gene. Among these mutations, HBB -28 (A>G) mutations is one of the three most common mutations in China and Southeast Asia patients with β-thalassemia. Correcting this mutation in human embryos may prevent the disease being passed onto future generations and cure anemia. Here we report the first study using base editor (BE) system to correct disease mutant in human embryos. Firstly, we produced a 293T cell line with an exogenous HBB -28 (A>G) mutant fragment for gRNAs and targeting efficiency evaluation. Then we collected primary skin fibroblast cells from a β-thalassemia patient with HBB -28 (A>G) homozygous mutation. Data showed that base editor could precisely correct HBB -28 (A>G) mutation in the patient's primary cells. To model homozygous mutation disease embryos, we constructed nuclear transfer embryos by fusing the lymphocyte or skin fibroblast cells with enucleated in vitro matured (IVM) oocytes. Notably, the gene correction efficiency was over 23.0% in these embryos by base editor. Although these embryos were still mosaic, the percentage of repaired blastomeres was over 20.0%. In addition, we found that base editor variants, with narrowed deamination window, could promote G-to-A conversion at HBB -28 site precisely in human embryos. Collectively, this study demonstrated the feasibility of curing genetic disease in human somatic cells and embryos by base editor system.

The Pan-STARRS1 Surveys

NASA Astrophysics Data System (ADS)

Chambers, Kenneth; Pan-STARRS Team

2018-01-01

The Pan-STARRS1 Surveys are complete and the first data release, DR1, is available from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. The data include a database of measured attributes of 3 billion objects, stacked images, and metadata of the 3pi Steradian Survey. The DR1 contains all stationary objects with mean and stack photometry registered on the GAIA astrometric frame. DR2 is in preparation and will be released this winter with all the individual epoch images and time domain photometry and forced photometry on the individual epoch images. The characteristics of the Pan-STARRS1 Surveys will be presented, including image quality, depth, cadence, and coverage. Measured attributes include PSF model magnitudes, aperture magnitudes, Kron Magnitudes, radial moments, Petrosian magnitudes, DeVaucoulers, Exponential, and Sersic magnitudes for extended objects. Images include total intensity, variance, and masks.An overview of the Pan-STARRS1 Surveys and data releases will be presented together with a brief description of the data collected since the end of the PS1 Science Consortium surveys, and the plans for the upcoming survey with PS1 and PS2 begining in February 2018.

PanCoreGen - Profiling, detecting, annotating protein-coding genes in microbial genomes.

PubMed

Paul, Sandip; Bhardwaj, Archana; Bag, Sumit K; Sokurenko, Evgeni V; Chattopadhyay, Sujay

2015-12-01

A large amount of genomic data, especially from multiple isolates of a single species, has opened new vistas for microbial genomics analysis. Analyzing the pan-genome (i.e. the sum of genetic repertoire) of microbial species is crucial in understanding the dynamics of molecular evolution, where virulence evolution is of major interest. Here we present PanCoreGen - a standalone application for pan- and core-genomic profiling of microbial protein-coding genes. PanCoreGen overcomes key limitations of the existing pan-genomic analysis tools, and develops an integrated annotation-structure for a species-specific pan-genomic profile. It provides important new features for annotating draft genomes/contigs and detecting unidentified genes in annotated genomes. It also generates user-defined group-specific datasets within the pan-genome. Interestingly, analyzing an example-set of Salmonella genomes, we detect potential footprints of adaptive convergence of horizontally transferred genes in two human-restricted pathogenic serovars - Typhi and Paratyphi A. Overall, PanCoreGen represents a state-of-the-art tool for microbial phylogenomics and pathogenomics study. Copyright © 2015 Elsevier Inc. All rights reserved.

Comparing maternal styles in bonobos (Pan paniscus) and chimpanzees (Pan troglodytes).

PubMed

De Lathouwers, Mieke; Van Elsacker, Linda

2004-12-01

Studies on Cercopithecine primate maternal styles, using factor analysis on a set of maternal behaviors, commonly render two factors that describe separate dimensions of maternal behavior: protectiveness and rejection. The aims of this study were to 1) investigate whether this method for determining maternal styles in Cercopithecine species can be applied to bonobos (Pan paniscus) and chimpanzees (Pan troglodytes), 2) determine whether they follow the same pattern, and 3) assess whether species differences in maternal style are apparent. We performed a factor analysis on nine maternal behaviors using data on eight mother-infant pairs of each species. This resulted in three factors: protectiveness, distance, and refusal. Protectiveness is positively correlated with time spent in ventral contact, making contact, approaching, and restraining. Distance is positively related with breaking contact and leaving. Refusal is positively correlated with rejecting and nipple-rejecting. The pattern of protectiveness corresponds with the pattern found in Cercopithecine species, suggesting a high consistency of this dimension across species and higher taxa. The retention of the other two factors indicates that in the Pan species, breaking contact and leaving represent another dimension, apart from rejecting and nipple-rejecting, which usually fall under one dimension in Cercopithecine species. An interspecific comparison of the factor scores for each dimension of maternal behavior reveals that, on average, bonobos and chimpanzees score equally on protectiveness. Scores on distance increase positively with infant age in chimpanzees, and negatively in bonobos, and on average bonobos have higher scores on refusal. These interspecies differences in maternal style are discussed in the light of interspecies differences in infant development, infant vulnerability to aggression, interbirth intervals, and female sociality. Copyright 2004 Wiley-Liss, Inc.

A "Situational" and "Coorientational" Measure of Specialized Magazine Editors' Perceptions of Readers.

ERIC Educational Resources Information Center

Jeffers, Dennis W.

A study was undertaken of specialized magazine editors' perceptions of audience characteristics as well as the perceived role of their publications. Specifically, the study examines the relationship between the editors' perceptions of reader problem recognition, level of involvement, constraint recognition, and possession of reference criteria and…

Preparation of durable flame retardant PAN fabrics based on amidoximation and phosphorylation

NASA Astrophysics Data System (ADS)

Zhang, Yue; Ren, Yuanlin; Liu, Xiaohui; Huo, Tongguo; Qin, Yiwen

2018-01-01

This paper aims to develop a method to impart polyacrylonitrile (PAN) fabric durable flame retadancy. PAN fabric was modified with hydroxylamine hydrochloride (HA) to prepare amidoxime PAN fabric (A-PAN) followed by phosphorylation with phosphoric acid (PA) to obtain flame retardant PAN fabric (P-A-PAN). Thermogravimetric (TG) analysis, differential scanning calorimetry (DSC), microscale combustion calorimetry (MCC) and pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS) were used to analyze the thermal degradation process and flame retardant mechanisms. The structure of the fabrics was characterized by Fourier transform infrared spectroscopy (FTIR) and X-ray Photoelectron Spectroscopy (XPS). The surface morphology of fabrics was observed by scanning electron microscope (SEM). Moreover, the flame retardancy of fabrics before and after washing was evaluated by Limiting oxygen index (LOI) and horizontal burning test. The results showed that the P-A-PAN possessed an excellent thermal stability with the highest LOI value of 34.1% and the highest char residue of 55.67% at 800 °C. Most importantly, the P-A-PAN possessed a wonderful flame retardant durability with a little decrease of LOI after 20 washing cycles. When they were ignited, the P-A-PAN fabrics before and after washing were both nonflammable due to the char residue formation of modified fabric.

The Pan-STARRS1 Survey Data Release

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.; Pan-STARRS Team

2017-01-01

The first Pan-STARRS1 Science Mission is complete and an initial Data Release 1, or DR1, including a database of measured attributes, stacked images, and metadata of the 3PI Survey, will be available from the STScI MAST archive. This release will contain all stationary objects with mean and stack photometry registered on the GAIA astrometric frame.The characteristics of the Pan-STARRS1 Surveys will be presented, including image quality, depth, cadence, and coverage. Measured attributes include PSF model magnitudes, aperture magnitudes, Kron Magnitudes, radial moments, Petrosian magnitudes, DeVaucoulers, Exponential, and Sersic magnitudes for extended objects. Images include total intensity, variance, and masks.An overview of both DR1 and the second data release DR2, to follow in the spring of 2017, will be presented. DR2 will add all time domain data and individual warped images. We will also report on the status of the Pan-STARRS2 Observatory and ongoing science with Pan-STARRS. The science from the PS1 surveys has included results in many t fields of astronomy from Near Earth Objects to cosmology.The Pan-STARRS1 Surveys have been made possible through contributions of the Institute for Astronomy of the University of Hawaii; the Pan-STARRS Project Office; the Max-Planck Society and its participating institutes: the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching; The Johns Hopkins University; Durham University; the University of Edinburgh; Queen's University Belfast; the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated; the National Central University of Taiwan; the Space Telescope Science Institute; the National Aeronautics and Space Administration under Grants No. NNX08AR22G, NNX12AR65G, NNX14AM74G issued through the Planetary Science Division of the NASA Science Mission Directorate; the National Science Foundation under Grant No. AST

INFLUENCE OF PEROXYACETYL NITRATE (PAN) ON WATER STRESS IN BEAN PLANTS

EPA Science Inventory

Bean plants (Phaseolus vulgaris) were exposed to 395 micrograms/cu m (0.08 ppm) peroxyacetyl nitrate (PAN) for 0.5 hr and subjected to drought stress following exposure. PAN influenced the plant water potential of PAN-sensitive 'Provider' resulting in visible wilting and reduced ...

A Fast Response Ammonia Sensor Based on Coaxial PPy-PAN Nanofiber Yarn.

PubMed

Liu, Penghong; Wu, Shaohua; Zhang, Yue; Zhang, Hongnan; Qin, Xiaohong

2016-06-23

Highly orientated polypyrrole (PPy)-coated polyacrylonitrile (PAN) (PPy-PAN) nanofiber yarn was prepared with an electrospinning technique and in-situ chemical polymerization. The morphology and chemical structure of PPy-PAN nanofiber yarn was characterized by scanning electron microscopy (SEM), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and fourier transform infrared spectroscopy (FTIR), which indicated that the PPy as the shell layer was homogeneously and uniformly polymerized on the surface of PAN nanofiber. The effects of different concentration of doping acid on the responses of PPy-PAN nanofiber yarn sensor were investigated. The electrical responses of the gas sensor based on the PPy-PAN nanofiber yarn to ammonia were investigated at room temperature. The nanoyarn sensor composed of uniaxially aligned PPy-PAN nanofibers with a one-dimensional structure exhibited a transient response, and the response time was less than 1 s. The excellent sensing properties mentioned above give rise to good potential application prospects in the field of ammonia sensor.

A Portable Burn Pan for the Disposal of Excess Propellants

DTIC Science & Technology

2016-06-01

of Vegetation in Vacinity of Burn Pan Caused by Radiant Heat ............... 32 Figure 12. Wet Propellant (120 kg) and Dry Propellant (460 kg) Burn...35 Figure 14. Graph of Component Temperatures During an HUTS Burn Pan Test ........................ 37 Figure 15. IR Camera Thermal...detector HUTS Howitzer Unit Training System burn pan IR Infrared JBER Joint Base Elmendorf Richardson (AK) Kg Kilogram m meter mg/kg milligram

The XML Metadata Editor of GFZ Data Services

NASA Astrophysics Data System (ADS)

Ulbricht, Damian; Elger, Kirsten; Tesei, Telemaco; Trippanera, Daniele

2017-04-01

Following the FAIR data principles, research data should be Findable, Accessible, Interoperable and Reuseable. Publishing data under these principles requires to assign persistent identifiers to the data and to generate rich machine-actionable metadata. To increase the interoperability, metadata should include shared vocabularies and crosslink the newly published (meta)data and related material. However, structured metadata formats tend to be complex and are not intended to be generated by individual scientists. Software solutions are needed that support scientists in providing metadata describing their data. To facilitate data publication activities of 'GFZ Data Services', we programmed an XML metadata editor that assists scientists to create metadata in different schemata popular in the earth sciences (ISO19115, DIF, DataCite), while being at the same time usable by and understandable for scientists. Emphasis is placed on removing barriers, in particular the editor is publicly available on the internet without registration [1] and the scientists are not requested to provide information that may be generated automatically (e.g. the URL of a specific licence or the contact information of the metadata distributor). Metadata are stored in browser cookies and a copy can be saved to the local hard disk. To improve usability, form fields are translated into the scientific language, e.g. 'creators' of the DataCite schema are called 'authors'. To assist filling in the form, we make use of drop down menus for small vocabulary lists and offer a search facility for large thesauri. Explanations to form fields and definitions of vocabulary terms are provided in pop-up windows and a full documentation is available for download via the help menu. In addition, multiple geospatial references can be entered via an interactive mapping tool, which helps to minimize problems with different conventions to provide latitudes and longitudes. Currently, we are extending the metadata editor

Sampling bee communities using pan traps: alternative methods increase sample size

USDA-ARS?s Scientific Manuscript database

Monitoring of the status of bee populations and inventories of bee faunas require systematic sampling. Efficiency and ease of implementation has encouraged the use of pan traps to sample bees. Efforts to find an optimal standardized sampling method for pan traps have focused on pan trap color. Th...

Ethics and the psychiatry journal editor: responsibilities and dilemmas.

PubMed

Greenberg, David; D Strous, Rael

2014-01-01

An array of potential ethical stumbling blocks awaits the editors of scientific journals. There are issues of particular relevance to mental health journals, and others unique to local journals with a relatively small circulation and low impact factor. The blind review system, conflict of interests, redundant publication, fraud and plagiarism, guest and ghost authorship and ghost writing, advertising, language and stigma, patient consent, and "rigging" the Impact Factor are all issues of importance. It is critical that editors are aware and informed of these important issues, and have an accessible forum for evaluating problems as they arise.

Letters to the Editor

NASA Astrophysics Data System (ADS)

1998-03-01

All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Comment on `Magnetic and electric field strengths of high voltage power lines and household appliances' José Luis Giordano Dept. de Ciencia y Tecnología de Materiales y Fluidos, CPSI, Universidad de Zaragoza, Spain Twins paradox S R Carson Norton College, Malton, North Yorkshire, UK On alternative ways of finding the ratio of specific heats of gases Tomas Ficker Physics Department, Technical University of Brno, Czech Republic

An international survey and modified Delphi process revealed editors' perceptions, training needs, and ratings of competency-related statements for the development of core competencies for scientific editors of biomedical journals.

PubMed

Galipeau, James; Cobey, Kelly D; Barbour, Virginia; Baskin, Patricia; Bell-Syer, Sally; Deeks, Jonathan; Garner, Paul; Shamseer, Larissa; Sharon, Straus; Tugwell, Peter; Winker, Margaret; Moher, David

2017-01-01

Background: Scientific editors (i.e., those who make decisions on the content and policies of a journal) have a central role in the editorial process at biomedical journals. However, very little is known about the training needs of these editors or what competencies are required to perform effectively in this role. Methods: We conducted a survey of perceptions and training needs among scientific editors from major editorial organizations around the world, followed by a modified Delphi process in which we invited the same scientific editors to rate the importance of competency-related statements obtained from a previous scoping review. Results: A total of 148 participants completed the survey of perceptions and training needs. At least 80% of participants agreed on six of the 38 skill and expertise-related statements presented to them as being important or very important to their role as scientific editors. At least 80% agreed on three of the 38 statements as necessary skills they perceived themselves as possessing (well or very well).  The top five items on participants' list of top training needs were training in statistics, research methods, publication ethics, recruiting and dealing with peer reviewers, and indexing of journals. The three rounds of the Delphi were completed by 83, 83, and 73 participants, respectively, which ultimately produced a list of 23 "highly rated" competency-related statements and another 86 "included" items. Conclusion: Both the survey and the modified Delphi process will be critical for understanding knowledge and training gaps among scientific editors when designing curriculum around core competencies in the future.

The PanCam Instrument for the ExoMars Rover

NASA Astrophysics Data System (ADS)

Coates, A. J.; Jaumann, R.; Griffiths, A. D.; Leff, C. E.; Schmitz, N.; Josset, J.-L.; Paar, G.; Gunn, M.; Hauber, E.; Cousins, C. R.; Cross, R. E.; Grindrod, P.; Bridges, J. C.; Balme, M.; Gupta, S.; Crawford, I. A.; Irwin, P.; Stabbins, R.; Tirsch, D.; Vago, J. L.; Theodorou, T.; Caballo-Perucha, M.; Osinski, G. R.; PanCam Team

2017-07-01

The scientific objectives of the ExoMars rover are designed to answer several key questions in the search for life on Mars. In particular, the unique subsurface drill will address some of these, such as the possible existence and stability of subsurface organics. PanCam will establish the surface geological and morphological context for the mission, working in collaboration with other context instruments. Here, we describe the PanCam scientific objectives in geology, atmospheric science, and 3-D vision. We discuss the design of PanCam, which includes a stereo pair of Wide Angle Cameras (WACs), each of which has an 11-position filter wheel and a High Resolution Camera (HRC) for high-resolution investigations of rock texture at a distance. The cameras and electronics are housed in an optical bench that provides the mechanical interface to the rover mast and a planetary protection barrier. The electronic interface is via the PanCam Interface Unit (PIU), and power conditioning is via a DC-DC converter. PanCam also includes a calibration target mounted on the rover deck for radiometric calibration, fiducial markers for geometric calibration, and a rover inspection mirror.

Experience with ATLAS MySQL PanDA database service

NASA Astrophysics Data System (ADS)

Smirnov, Y.; Wlodek, T.; De, K.; Hover, J.; Ozturk, N.; Smith, J.; Wenaus, T.; Yu, D.

2010-04-01

The PanDA distributed production and analysis system has been in production use for ATLAS data processing and analysis since late 2005 in the US, and globally throughout ATLAS since early 2008. Its core architecture is based on a set of stateless web services served by Apache and backed by a suite of MySQL databases that are the repository for all PanDA information: active and archival job queues, dataset and file catalogs, site configuration information, monitoring information, system control parameters, and so on. This database system is one of the most critical components of PanDA, and has successfully delivered the functional and scaling performance required by PanDA, currently operating at a scale of half a million jobs per week, with much growth still to come. In this paper we describe the design and implementation of the PanDA database system, its architecture of MySQL servers deployed at BNL and CERN, backup strategy and monitoring tools. The system has been developed, thoroughly tested, and brought to production to provide highly reliable, scalable, flexible and available database services for ATLAS Monte Carlo production, reconstruction and physics analysis.

Pan-sharpening via compressed superresolution reconstruction and multidictionary learning

NASA Astrophysics Data System (ADS)

Shi, Cheng; Liu, Fang; Li, Lingling; Jiao, Licheng; Hao, Hongxia; Shang, Ronghua; Li, Yangyang

2018-01-01

In recent compressed sensing (CS)-based pan-sharpening algorithms, pan-sharpening performance is affected by two key problems. One is that there are always errors between the high-resolution panchromatic (HRP) image and the linear weighted high-resolution multispectral (HRM) image, resulting in spatial and spectral information lost. The other is that the dictionary construction process depends on the nontruth training samples. These problems have limited applications to CS-based pan-sharpening algorithm. To solve these two problems, we propose a pan-sharpening algorithm via compressed superresolution reconstruction and multidictionary learning. Through a two-stage implementation, compressed superresolution reconstruction model reduces the error effectively between the HRP and the linear weighted HRM images. Meanwhile, the multidictionary with ridgelet and curvelet is learned for both the two stages in the superresolution reconstruction process. Since ridgelet and curvelet can better capture the structure and directional characteristics, a better reconstruction result can be obtained. Experiments are done on the QuickBird and IKONOS satellites images. The results indicate that the proposed algorithm is competitive compared with the recent CS-based pan-sharpening methods and other well-known methods.

22. RW Meyer Sugar Mill: 18761889. Sorghum Pan. Manufactured by ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. RW Meyer Sugar Mill: 1876-1889. Sorghum Pan. Manufactured by John Nott & Co., Honolulu, Hawaii, 1878. View: Historical view, 1934, T.T. Waterman Collection, Hawaiian Sugar Planters' Association, Oahu, Hawaii. View looking toward east end of sorghum pan and interior of east end of the boiling house. Walls and final compartment of the sorghum pan are still intact. - R. W. Meyer Sugar Mill, State Route 47, Kualapuu, Maui County, HI

Multi-component testing using HZ-PAN and AgZ-PAN Sorbents for OSPREY Model validation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garn, Troy G.; Greenhalgh, Mitchell; Lyon, Kevin L.

2015-04-01

In efforts to further develop the capability of the Off-gas SeParation and RecoverY (OSPREY) model, multi-component tests were completed using both HZ-PAN and AgZ-PAN sorbents. The primary purpose of this effort was to obtain multi-component xenon and krypton capacities for comparison to future OSPREY predicted multi-component capacities using previously acquired Langmuir equilibrium parameters determined from single component isotherms. Experimental capacities were determined for each sorbent using two feed gas compositions of 1000 ppmv xenon and 150 ppmv krypton in either a helium or air balance. Test temperatures were consistently held at 220 K and the gas flowrate was 50 sccm.more » Capacities were calculated from breakthrough curves using TableCurve® 2D software by Jandel Scientific. The HZ-PAN sorbent was tested in the custom designed cryostat while the AgZ-PAN was tested in a newly installed cooling apparatus. Previous modeling validation efforts indicated the OSPREY model can be used to effectively predict single component xenon and krypton capacities for both engineered form sorbents. Results indicated good agreement with the experimental and predicted capacity values for both krypton and xenon on the sorbents. Overall, the model predicted slightly elevated capacities for both gases which can be partially attributed to the estimation of the parameters and the uncertainty associated with the experimental measurements. Currently, OSPREY is configured such that one species adsorbs and one does not (i.e. krypton in helium). Modification of OSPREY code is currently being performed to incorporate multiple adsorbing species and non-ideal interactions of gas phase species with the sorbent and adsorbed phases. Once these modifications are complete, the sorbent capacities determined in the present work will be used to validate OSPREY multicomponent adsorption predictions.« less

Spontaneous triadic engagement in bonobos (Pan paniscus) and chimpanzees (Pan troglodytes).

PubMed

MacLean, Evan; Hare, Brian

2013-08-01

Humans are believed to have evolved a unique motivation to participate in joint activities that first develops during infancy and supports the development of shared intentionality. We conducted five experiments with bonobos (Pan paniscus) and chimpanzees (Pan troglodytes) (Total n = 119) to assess their motivation to spontaneously participate in joint activities with a conspecific or a human. We found that even the youngest subjects preferred to interact together with a human and a toy rather than engaging in an identical game alone. In addition, we found that subjects could spontaneously interact with a human in a turn-taking game involving passing a ball back and forth and used behaviors to elicit additional interaction when the game was disrupted. However, when paired with a conspecific, subjects preferred to interact with an object individually rather than together. Our results indicate that nonhuman apes are motivated to engage in triadic activities if they occur spontaneously with humans and require a minimum amount of coordination. These findings leave open the question of whether these activities are coordinated through shared intentions.

Open Simulation Laboratories [Guest editors' introduction

DOE PAGES

Alexander, Francis J.; Meneveau, Charles

2015-09-01

The introduction for the special issue on open simulation laboratories, the guest editors describe how OSLs will become more common as their potential is better understood and they begin providing access to valuable datasets to much larger segments of the scientific community. Moreover, new analysis tools and ways to do science will inevitably develop as a result.

PanGEA: identification of allele specific gene expression using the 454 technology.

PubMed

Kofler, Robert; Teixeira Torres, Tatiana; Lelley, Tamas; Schlötterer, Christian

2009-05-14

Next generation sequencing technologies hold great potential for many biological questions. While mainly used for genomic sequencing, they are also very promising for gene expression profiling. Sequencing of cDNA does not only provide an estimate of the absolute expression level, it can also be used for the identification of allele specific gene expression. We developed PanGEA, a tool which enables a fast and user-friendly analysis of allele specific gene expression using the 454 technology. PanGEA allows mapping of 454-ESTs to genes or whole genomes, displaying gene expression profiles, identification of SNPs and the quantification of allele specific gene expression. The intuitive GUI of PanGEA facilitates a flexible and interactive analysis of the data. PanGEA additionally implements a modification of the Smith-Waterman algorithm which deals with incorrect estimates of homopolymer length as occuring in the 454 technology To our knowledge, PanGEA is the first tool which facilitates the identification of allele specific gene expression. PanGEA is distributed under the Mozilla Public License and available at: http://www.kofler.or.at/bioinformatics/PanGEA

Error Pattern Analysis Applied to Technical Writing: An Editor's Guide for Writers.

ERIC Educational Resources Information Center

Monagle, E. Brette

The use of error pattern analysis can reduce the time and money spent on editing and correcting manuscripts. What is required is noting, classifying, and keeping a frequency count of errors. First an editor should take a typical page of writing and circle each error. After the editor has done a sufficiently large number of pages to identify an…

PAN and O3 enhancement at Taehwa Research Forest in Korea

NASA Astrophysics Data System (ADS)

Gil, J.; Lee, M.; Rhee, H.; Lee, Y.; Park, H.; Kim, S.

2017-12-01

PAN (Peroxyacetyl Nitrate) is one of the most important secondary pollutant produced by the reaction of NOx (= NO + NO2) and oxygenated VOCs (Volatile Organic Compounds). It is considered more reliable indicator of photochemical pollution than O3 in urban area. To observe the evolution of biogenic emission being mixed with urban pollutants, measurement was conducted at TRF (Taehwa Research Forest) near SMA (Seoul Metropolitan Area) in Korea during 2012, and 2013. PAN with reactive gases (O3, NOx, CO, SO2) were measured at six heights (4.1, 9.5, 15, 20, 31, 39 m) of a 41m tower along with BVOCs (Biogenic Volatile Organic Compounds). PAN was measured using a fast GC-LCD (Gas Chromatography with Luminol-based Chemiluminescence Detection). For PAN and O3, the 5%ile, 50%ile, and 95%ile were 0.12 ppbv, 0.46 ppbv, and 2.09 ppbv, and 18.4 ppbv, 44.7 ppbv, and 66.6 ppbv respectively. PAN was visibly higher during warm seasons (0.69 ppbv) than cold seasons (0.35 ppbv) and their monthly mean concentrations were the highest in June. The PAN maxima (7.78 ppbv) was observed in August 2013 with the elevation of O3 and NOx. It is noteworthy that there were enhancement of PAN and O3 around 6 PM, along with isoprene emission and a sudden increase of NO2 near the time for enhancement. A F0AM (Framework for 0-D Atmospheric Modeling) was used to identify the contribution of BVOCs and NOx to PAN and O3 enhancement.

An increasing problem in publication ethics: Publication bias and editors' role in avoiding it.

PubMed

Ekmekci, Perihan Elif

2017-06-01

Publication bias is defined as "the tendency on the parts of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or the strength of the study findings."Publication bias distorts the accumulated data in the literature, causes the over estimation of potential benefits of intervention and mantles the risks and adverse effects, and creates a barrier to assessing the clinical utility of drugs as well as evaluating the long-term safety of medical interventions. The World Medical Association, the International Committee of Medical Journals, and the Committee on Publication Ethics have conferred responsibilities and ethical obligations to editors concerning the avoidance of publication bias. Despite the explicit statements in these international documents, the editors' role in and ability to avoid publication bias is still being discussed. Unquestionably, all parties involved in clinical research have the ultimate responsibility to sustain the research integrity and validity of accumulated general knowledge. Cooperation and commitment is required at every step of a clinical trial. However, this holistic approach does not exclude effective measures to be taken at the editors' level. The editors of major medical journals concluded that one precaution that editors can take is to mandate registration of all clinical trials in a public repository as a precondition to submitting manuscripts to journals. Raising awareness regarding the value of publishing negative data for the scientific community and human health, and increasing the number of journals that are dedicated to publishing negative results or that set aside a section in their pages to do so, are positive steps editors can take to avoid publication bias.

The future of PanDA in ATLAS distributed computing

NASA Astrophysics Data System (ADS)

De, K.; Klimentov, A.; Maeno, T.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.

2015-12-01

Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, while data processing requires more than a few billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of locally managed computing in HEP was discarded in favour of a far more automated, flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at more than a million computing jobs per day, and processing over an exabyte of data in 2013. There are many new challenges that PanDA will face in the near future, in addition to new challenges of scale, heterogeneity and increasing user base. PanDA will need to handle rapidly changing computing infrastructure, will require factorization of code for easier deployment, will need to incorporate additional information sources including network metrics in decision making, be able to control network circuits, handle dynamically sized workload processing, provide improved visualization, and face many other challenges. In this talk we will focus on the new features, planned or recently implemented, that are relevant to the next decade of distributed computing workload management using PanDA.

Evolution of the ATLAS PanDA workload management system for exascale computational science

NASA Astrophysics Data System (ADS)

Maeno, T.; De, K.; Klimentov, A.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.; Yu, D.; Atlas Collaboration

2014-06-01

An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated at a very large scale the value of automated dynamic brokering of diverse workloads across distributed computing resources. The next generation of PanDA will allow other data-intensive sciences and a wider exascale community employing a variety of computing platforms to benefit from ATLAS' experience and proven tools.

From evaporating pans to transpiring plants (John Dalton Medal Lecture)

NASA Astrophysics Data System (ADS)

Roderick, Michael

2013-04-01

The name of the original inventor of irrigated agriculture is lost to antiquity. Nevertheless, one can perhaps imagine an inquisitive desert inhabitant noting the greener vegetation along a watercourse and putting two and two together. Once water was being supplied and food was being produced it would be natural to ask a further question: how much water can we put on? No doubt much experience was gained down through the ages, but again, one can readily imagine someone inverting a rain gauge, filling it with water and measuring how fast the water evaporated. The inverted rain gauge measures the demand for water by the atmosphere. We call it the evaporative demand. I do not know if this is what actually happened but it sure makes an interesting start to a talk. Evaporation pans are basically inverted rain gauges. The rain gauge and evaporation pan measure the supply and demand respectively and these instruments are the workhorses of agricultural meteorology. Rain gauges are well known. Evaporation pans are lesser known but are in widespread use and are a key part of several national standardized meteorological networks. Many more pans are used for things like scheduling irrigation on farms or estimating evaporation from lakes. Analysis of the long records now available from standardized networks has revealed an interesting phenomenon, i.e., pan evaporation has increased in some places and decreased in other but when averaged over large numbers of pans there has been a steady decline. These independent reports from, for example, the US, Russia, China, India, Thailand, are replicated in the southern hemisphere in, for example, Australia, New Zealand and South Africa. One often hears the statement that because the earth is expected to warm with increasing greenhouse gas emissions then it follows that water will evaporate faster. The pan evaporation observations show that this widely held expectation is wrong. When expectations disagree with observations, it is the

The saliva microbiome of Pan and Homo

PubMed Central

2013-01-01

Background It is increasingly recognized that the bacteria that live in and on the human body (the microbiome) can play an important role in health and disease. The composition of the microbiome is potentially influenced by both internal factors (such as phylogeny and host physiology) and external factors (such as diet and local environment), and interspecific comparisons can aid in understanding the importance of these factors. Results To gain insights into the relative importance of these factors on saliva microbiome diversity, we here analyze the saliva microbiomes of chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) from two sanctuaries in Africa, and from human workers at each sanctuary. The saliva microbiomes of the two Pan species are more similar to one another, and the saliva microbiomes of the two human groups are more similar to one another, than are the saliva microbiomes of human workers and apes from the same sanctuary. We also looked for the existence of a core microbiome and find no evidence for a taxon-based core saliva microbiome for Homo or Pan. In addition, we studied the saliva microbiome from apes from the Leipzig Zoo, and found an extraordinary diversity in the zoo ape saliva microbiomes that is not found in the saliva microbiomes of the sanctuary animals. Conclusions The greater similarity of the saliva microbiomes of the two Pan species to one another, and of the two human groups to one another, are in accordance with both the phylogenetic relationships of the hosts as well as with host physiology. Moreover, the results from the zoo animals suggest that novel environments can have a large impact on the microbiome, and that microbiome analyses based on captive animals should be viewed with caution as they may not reflect the microbiome of animals in the wild. PMID:24025115

The ATLAS PanDA Monitoring System and its Evolution

NASA Astrophysics Data System (ADS)

Klimentov, A.; Nevski, P.; Potekhin, M.; Wenaus, T.

2011-12-01

The PanDA (Production and Distributed Analysis) Workload Management System is used for ATLAS distributed production and analysis worldwide. The needs of ATLAS global computing imposed challenging requirements on the design of PanDA in areas such as scalability, robustness, automation, diagnostics, and usability for both production shifters and analysis users. Through a system-wide job database, the PanDA monitor provides a comprehensive and coherent view of the system and job execution, from high level summaries to detailed drill-down job diagnostics. It is (like the rest of PanDA) an Apache-based Python application backed by Oracle. The presentation layer is HTML code generated on the fly in the Python application which is also responsible for managing database queries. However, this approach is lacking in user interface flexibility, simplicity of communication with external systems, and ease of maintenance. A decision was therefore made to migrate the PanDA monitor server to Django Web Application Framework and apply JSON/AJAX technology in the browser front end. This allows us to greatly reduce the amount of application code, separate data preparation from presentation, leverage open source for tools such as authentication and authorization mechanisms, and provide a richer and more dynamic user experience. We describe our approach, design and initial experience with the migration process.

The PanCam Instrument for the ExoMars Rover

PubMed Central

Coates, A.J.; Jaumann, R.; Griffiths, A.D.; Leff, C.E.; Schmitz, N.; Josset, J.-L.; Paar, G.; Gunn, M.; Hauber, E.; Cousins, C.R.; Cross, R.E.; Grindrod, P.; Bridges, J.C.; Balme, M.; Gupta, S.; Crawford, I.A.; Irwin, P.; Stabbins, R.; Tirsch, D.; Vago, J.L.; Theodorou, T.; Caballo-Perucha, M.; Osinski, G.R.

2017-01-01

Abstract The scientific objectives of the ExoMars rover are designed to answer several key questions in the search for life on Mars. In particular, the unique subsurface drill will address some of these, such as the possible existence and stability of subsurface organics. PanCam will establish the surface geological and morphological context for the mission, working in collaboration with other context instruments. Here, we describe the PanCam scientific objectives in geology, atmospheric science, and 3-D vision. We discuss the design of PanCam, which includes a stereo pair of Wide Angle Cameras (WACs), each of which has an 11-position filter wheel and a High Resolution Camera (HRC) for high-resolution investigations of rock texture at a distance. The cameras and electronics are housed in an optical bench that provides the mechanical interface to the rover mast and a planetary protection barrier. The electronic interface is via the PanCam Interface Unit (PIU), and power conditioning is via a DC-DC converter. PanCam also includes a calibration target mounted on the rover deck for radiometric calibration, fiducial markers for geometric calibration, and a rover inspection mirror. Key Words: Mars—ExoMars—Instrumentation—Geology—Atmosphere—Exobiology—Context. Astrobiology 17, 511–541.

EDITORIAL: Incoming Editor-in-Chief

NASA Astrophysics Data System (ADS)

Lidström, Suzanne

2012-04-01

When Professor Anders Bárány took over as the Executive Editor of Physica Scripta, in 1986, he talked of his trepidation at having to 'dress himself' in his predecessor's 'editorial coveralls'. At that time, they had been worn by Professor Nils Robert Nilsson, a major figure in the physics community, for almost 20 years. Just one year prior to this, Professor Roger Wäppling had been recruited to the position of Subeditor in conjunction with a decision to expand the number of contributions in the field of condensed matter physics, to turn it into one of the dominant subjects in the broad-based journal. Physica Scripta had already gained a reputation for being a high quality journal with wide coverage of both experimental and theoretical physics. Interestingly, in the mid 1980s, the number of papers submitted had been growing and an impressive 250 submissions per year had been attained, with all of the manuscripts being handled in-house. Not many miles away in the town of Uppsala, a group of English students was stepping off a train on a magnificent snowy day in January to embark on their final year projects. A couple of us enjoyed ourselves so much that we stayed on afterwards as PhD students, thereby encountering the mixed pleasure of studying physics in a second language for the first time. I used to copy the notes down meticulously in Swedish, then try to work backwards with a textbook to improve my language skills. One day, returning from a particularly incomprehensible lecture on solid state physics, I showed my roommates my notes and asked if they could please explain what the lecture had been about: 'I don't know', they replied, 'but this bit is about sheep!' Meanwhile, back at Physica Scripta, the journal continued to flourish: 400 submissions were received in 1996, and the march of progress was well underway. Manuscripts could now be sent in on disks and Physica Scripta was available on the World Wide Web. Roger was appointed to manage the journal and

The Pan-STARRS search for Near-Earth Objects

NASA Astrophysics Data System (ADS)

Wainscoat, Richard J.; Weryk, Robert; Chambers, Kenneth

2018-01-01

The Pan-STARRS1 telescope on Haleakala, Hawaii has become the leading discovery telescope for Near-Earth Objects (NEOs), and is now responsible for discovering almost half of all new NEOs, more than half of all larger NEOs, and more than half of all new comets. The survey routinely reaches depths of V=22 or fainter (in dark sky conditions) over an area of approximately 1,000 square degrees per night. The survey strategy will be described. The survey will soon be augmented by the addition of the Pan-STARRS2 telescope, which has similar optics and an improved camera, and which will roughly double the survey power. A sample of the important recent solar system discoveries made by the Pan-STARRS survey will be summarized.

Characterization of low thermal conductivity PAN-based carbon fibers

NASA Technical Reports Server (NTRS)

Katzman, Howard A.; Adams, P. M.; Le, T. D.; Hemminger, Carl S.

1992-01-01

The microstructure and surface chemistry of eight low thermal conductivity (LTC) PAN-based carbon fibers were determined and compared with PAN-based fibers heat treated to higher temperatures. Based on wide-angle x ray diffraction, the LTC PAN fibers all appear to have a similar turbostratic structure with large 002 d-spacings, small crystallite sizes, and moderate preferred orientation. Limited small-angle x ray scattering (SAXS) results indicate that, with the exception of LTC fibers made by BASF, the LTC fibers do not have well developed pores. Transmission electron microscopy shows that the texture of the two LTC PAN-based fibers studied (Amoco T350/23X and /25X) consists of multiple sets of parallel, wavy, bent layers that interweave with each other forming a complex three dimensional network oriented randomly around the fiber axis. X ray photoelectron spectroscopy (XPS) analysis finds correlations between heat treated temperatures and the surface composition chemistry of the carbon fiber samples.

15. RW Meyer Sugar Mill: 18761889. Sorghum pan and boiling ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. RW Meyer Sugar Mill: 1876-1889. Sorghum pan and boiling range flue. Manufactured by John Nott & Co., Honolulu, Hawaii, 1878. View: North side of sorghum pan and boiling range flue, with furnace-end in background. In the sorghum pan heat was applied to the cane juice to clarify it, evaporate its water content, and concentrate the sugar crystals. Hot gasses moved through the flue underneath the entire copper bottom of the sorghum pan from the furnace end (in background) to the smokestack end (in foreground). After the hot cane juice moved through the separate compartments until it reached the final compartment (now missing two sides) where it was drawn out from the copper lip in the corner. - R. W. Meyer Sugar Mill, State Route 47, Kualapuu, Maui County, HI

What a Book Editor Does All Day.

ERIC Educational Resources Information Center

Allen, Patricia

1982-01-01

Describes the major tasks that an editor for a commercial publishing house, in this case a children's book publisher, performs on a day-to-day basis, including manuscript selection, working with authors and illustrators in completing a book, scheduling books for publication, and managing economic and production activities. (JL)

The ATLAS PanDA Pilot in Operation

NASA Astrophysics Data System (ADS)

Nilsson, P.; Caballero, J.; De, K.; Maeno, T.; Stradling, A.; Wenaus, T.; ATLAS Collaboration

2011-12-01

The Production and Distributed Analysis system (PanDA) [1-2] was designed to meet ATLAS [3] requirements for a data-driven workload management system capable of operating at LHC data processing scale. Submitted jobs are executed on worker nodes by pilot jobs sent to the grid sites by pilot factories. This paper provides an overview of the PanDA pilot [4] system and presents major features added in light of recent operational experience, including multi-job processing, advanced job recovery for jobs with output storage failures, gLExec [5-6] based identity switching from the generic pilot to the actual user, and other security measures. The PanDA system serves all ATLAS distributed processing and is the primary system for distributed analysis; it is currently used at over 100 sites worldwide. We analyze the performance of the pilot system in processing real LHC data on the OSG [7], EGI [8] and Nordugrid [9-10] infrastructures used by ATLAS, and describe plans for its evolution.

Magazine Article Placement: How Editors, Regular Contributors, and Novice Writers Rate Query Letters.

ERIC Educational Resources Information Center

Jolliffe, Lee

About 350,000 freelance magazine articles were purchased by magazine editors last year from the 22,000 freelancers and 225,000 would-be freelancers in the United States. A study examined the factors editors judge most important in selecting freelance magazine article proposals, using factor analysis and qualitative examination of persuasive…

Letter to the editor of TAAP, in response to letter from Anders et al.

EPA Science Inventory

To the Editor, Toxicology and Applied Pharmacology: We would like to address the letter to the editor submitted by Anders et al. regarding the substantive issues raised regarding our paper "Evaluation of two different metabolic hypotheses for dichloromethane toxicity using physi...

Kinematic measurement from panned cinematography.

PubMed

Gervais, P; Bedingfield, E W; Wronko, C; Kollias, I; Marchiori, G; Kuntz, J; Way, N; Kuiper, D

1989-06-01

Traditional 2-D cinematography has used a stationary camera with its optical axis perpendicular to the plane of motion. This method has constrained the size of the object plane or has introduced potential errors from a small subject image size with large object field widths. The purpose of this study was to assess a panning technique that could overcome the inherent limitations of small object field widths, small object image sizes and limited movement samples. The proposed technique used a series of reference targets in the object field that provided the necessary scales and origin translations. A 102 m object field was panned. Comparisons between criterion distances and film measured distances for field widths of 46 m and 22 m resulted in absolute mean differences that were comparable to that of the traditional method.

Editors' report, 2012.

PubMed

García-Puig, J; Alonso-Vega, G Gaspar; Ríos-Blanco, J J

2013-01-01

The editors of Revista Clínica Española (Rev Clin Esp) inform on their editorial activity during the last 12 months: a) objectives and attainments; b) editorial activity; and c) objectives for 2013. In 2012 the most relevant modifications concerning the editorial activity have been: a) revision by the responsible editor of all manuscripts sent to peer review, and b) translation into English of five manuscripts with abstract of each issue. From the first January to the 30th September 2012 we handled 457 manuscripts (50 manuscripts per month) a figure 22.5% higher than in 2011 (40.8 manuscripts per month). We have accepted 27.2% of all manuscripts (originals, 13.0%). We asked for 295 revisions to 241 reviewers and we have received 66.1% of the revisions asked for in less than two weeks (mean time to receive a revision, 11.3 days). The mean time to adopt an editorial decision for all manuscripts («accept»/«reject») has been 23.9 days (31.3 days in 2011; 35.4 in 2010). This figure has been 29.4 days for the original manuscripts (9.5 and 12.3 days less than in 2011 and 2010, respectively). The mean time taken since a manuscript is received to publication has dropped from 203 days in 2010, 168 in 2011 and 115 in 2012 (less than 3 months). The collaboration with the working groups has reported 19 published manuscripts in 2012. We hope that in 2013 both the English version and the digitalization of Rev Clin Esp from 1940 to 1999 (the journal is already digitalized since 2000) will become a reality. The renewal of the actual sections (i.e., clinical conference, an image for a diagnosis) pretends, with the collaboration of all, to make our journal, each day, better. Copyright © 2012 Elsevier España, S.L. All rights reserved.

RPAN: rice pan-genome browser for ∼3000 rice genomes.

PubMed

Sun, Chen; Hu, Zhiqiang; Zheng, Tianqing; Lu, Kuangchen; Zhao, Yue; Wang, Wensheng; Shi, Jianxin; Wang, Chunchao; Lu, Jinyuan; Zhang, Dabing; Li, Zhikang; Wei, Chaochun

2017-01-25

A pan-genome is the union of the gene sets of all the individuals of a clade or a species and it provides a new dimension of genome complexity with the presence/absence variations (PAVs) of genes among these genomes. With the progress of sequencing technologies, pan-genome study is becoming affordable for eukaryotes with large-sized genomes. The Asian cultivated rice, Oryza sativa L., is one of the major food sources for the world and a model organism in plant biology. Recently, the 3000 Rice Genome Project (3K RGP) sequenced more than 3000 rice genomes with a mean sequencing depth of 14.3×, which provided a tremendous resource for rice research. In this paper, we present a genome browser, Rice Pan-genome Browser (RPAN), as a tool to search and visualize the rice pan-genome derived from 3K RGP. RPAN contains a database of the basic information of 3010 rice accessions, including genomic sequences, gene annotations, PAV information and gene expression data of the rice pan-genome. At least 12 000 novel genes absent in the reference genome were included. RPAN also provides multiple search and visualization functions. RPAN can be a rich resource for rice biology and rice breeding. It is available at http://cgm.sjtu.edu.cn/3kricedb/ or http://www.rmbreeding.cn/pan3k. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Disordered eating and food restrictions in children with PANDAS/PANS.

PubMed

Toufexis, Megan D; Hommer, Rebecca; Gerardi, Diana M; Grant, Paul; Rothschild, Leah; D'Souza, Precilla; Williams, Kyle; Leckman, James; Swedo, Susan E; Murphy, Tanya K

2015-02-01

Sudden onset clinically significant eating restrictions are a defining feature of the clinical presentation of some of the cases of pediatric acute-onset neuropsychiatric syndrome (PANS). Restrictions in food intake are typically fueled by contamination fears; fears of choking, vomiting, or swallowing; and/or sensory issues, such as texture, taste, or olfactory concerns. However, body image distortions may also be present. We investigate the clinical presentation of PANS disordered eating and compare it with that of other eating disorders. We describe 29 patients who met diagnostic criteria for PANS. Most also exhibited evidence that the symptoms might be sequelae of infections with Group A streptococcal bacteria (the pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections [PANDAS] subgroup of PANS). The clinical presentations are remarkable for a male predominance (2:1 M:F), young age of the affected children (mean=9 years; range 5-12 years), acuity of symptom onset, and comorbid neuropsychiatric symptoms. The food refusal associated with PANS is compared with symptoms listed for the new Diagnostic and Statistical Manual of Mental Disorders, 5th ed. (DSM-V) diagnosis of avoidant/restrictive food intake disorder (ARFID). Treatment implications are discussed, as well as directions for further research.

FloorspaceJS - A New, Open Source, Web-Based Geometry Editor for Building Energy Modeling (BEM): Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Macumber, Daniel L; Horowitz, Scott G; Schott, Marjorie

Across most industries, desktop applications are being rapidly migrated to web applications for a variety of reasons. Web applications are inherently cross platform, mobile, and easier to distribute than desktop applications. Fueling this trend are a wide range of free, open source libraries and frameworks that make it incredibly easy to develop powerful web applications. The building energy modeling community is just beginning to pick up on these larger trends, with a small but growing number of building energy modeling applications starting on or moving to the web. This paper presents a new, open source, web based geometry editor formore » Building Energy Modeling (BEM). The editor is written completely in JavaScript and runs in a modern web browser. The editor works on a custom JSON file format and is designed to be integrated into a variety of web and desktop applications. The web based editor is available to use as a standalone web application at: https://nrel.github.io/openstudio-geometry-editor/. An example integration is demonstrated with the OpenStudio desktop application. Finally, the editor can be easily integrated with a wide range of possible building energy modeling web applications.« less

Magazine Editors and the Writing Process: An Analysis of How Editors Work with Staff and Free-Lance Writers.

ERIC Educational Resources Information Center

Schierhorn, Ann B.; Endres, Kathleen L.

Editors of business and consumer magazines chosen by a random sample were asked in a mail survey what method they used in working with staff writers and free-lance writers. They were asked how they work with writers in the five stages of the writing process--idea, reporting, organizing, writing and rewriting. The first mailing to consumer…

Smart Polyacrylonitrile (PAN) Nanofibers with Thermal Energy Storage and Retrieval Functionality

NASA Astrophysics Data System (ADS)

Cherry, De'Andre James

Phase change materials (PCMs) are generally substances with a high heat of fusion in the process of solid to liquid phase change. The nature of PCMs make them efficient materials to store and retrieve large amounts of thermal energy. Presently, high efficiency thermal energy storage/retrieval in applications where flexibility and space saving are required, such as smart textiles, still remains as a challenge. In this study, lauric acid (LA) and myristic acid (MA) were combined to prepare a specific binary fatty acid eutectic (LA-MA) with a melting point near the operating body temperature of a human being and then encapsulated in polyacrylonitrile (PAN) nanofibers through the electrospinning technique. Functionalized PCM-enhanced PAN nanofibers containing LA-MA at 30%, 50%, 70% and 100% of the weight of the PAN were successfully synthesized. The morphological structures and thermal energy storage capacity of the PCM-enhanced PAN nanofibers were characterized by electron microscopy (EM) and differential scanning calorimetry (DSC). The novel PCM-enhanced PAN nanofibers maintained their cylindrical fiber morphology after multiple heating-cooling cycles and retained their latent heat storage functionality. Thus, it is envisioned that the prepared PCM-enhanced PAN nanofibers will find use in applications such as smart textiles where temperature regulation functionality is required.

PanGEA: Identification of allele specific gene expression using the 454 technology

PubMed Central

Kofler, Robert; Teixeira Torres, Tatiana; Lelley, Tamas; Schlötterer, Christian

2009-01-01

Background Next generation sequencing technologies hold great potential for many biological questions. While mainly used for genomic sequencing, they are also very promising for gene expression profiling. Sequencing of cDNA does not only provide an estimate of the absolute expression level, it can also be used for the identification of allele specific gene expression. Results We developed PanGEA, a tool which enables a fast and user-friendly analysis of allele specific gene expression using the 454 technology. PanGEA allows mapping of 454-ESTs to genes or whole genomes, displaying gene expression profiles, identification of SNPs and the quantification of allele specific gene expression. The intuitive GUI of PanGEA facilitates a flexible and interactive analysis of the data. PanGEA additionally implements a modification of the Smith-Waterman algorithm which deals with incorrect estimates of homopolymer length as occuring in the 454 technology Conclusion To our knowledge, PanGEA is the first tool which facilitates the identification of allele specific gene expression. PanGEA is distributed under the Mozilla Public License and available at: PMID:19442283

Message from the Editor

NASA Astrophysics Data System (ADS)

Stambaugh, Ronald D.

2014-01-01

This last year being an odd numbered year, the pages of Nuclear Fusion saw a large influx of expanded papers from the 2012 Fusion Energy Conference in San Diego. Many papers have focused on the scientific and technical challenges posed by ITER. Contributions are steadily increasing from the new superconducting tokamaks in Asia. The ITER Project continues to move ahead. Construction at the Cadarache site is quite remarkable. Buildings completed include the huge Poloidal Field Coils Winding Facility and the Headquarters building, which has been occupied by the ITER staff. Work is progressing on the Assembly building and the Cryostat Workshop. The base of the tokamak complex is being laid. Besides the construction that is taking place and will take place at the site, components from around the world have to navigate the complex route from Marseilles to the site. A test convoy replicating the dimensions and weights of the most exceptional ITER loads successfully traversed that route in 2013. We are pleased to report that the IAEA and ITER have finalized the agreement for ITER authors to publish papers in Nuclear Fusion . Nuclear Fusion is proud to continue its key role in providing the leading forum for the documentation of scientific progress and exchange of research results internationally toward fusion energy. Refereeing The Nuclear Fusion editorial office appreciates greatly the effort made by our referees to sustain the high quality of the journal. Since January 2005, we have been offering the most active referees over the past year a personal subscription to Nuclear Fusion with electronic access for one year, free of charge. We have excluded our Board Members, Guest Editors of special editions and those referees who were already listed in previous years. The following people have been selected: J.M. Canik, Oak Ridge National Laboratory, USA I.T. Chapman, Culham Centre for Fusion Energy, UK L.-G. Eriksson, Commission of the European Communities, Belgium T. Evans

EDITORIAL: A word from the new Editor-in-Chief A word from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Mostowski, Jan

2011-01-01

TIn the autumn of 2010 I became the Editor-in Chief of European Journal of Physics (EJP). EJP is a place for teachers, instructors and professors to exchange their views on teaching physics at university level and share their experience. It is general opinion that no good research is possible without connection with good, high-quality teaching, at the university level in particular. Therefore excellence in physics teaching is important to the physics community. European Journal of Physics is proud of its contribution to achieving this goal. As Editor-in-Chief, I will continue to work to this general objective of the journal. We will publish articles on specific topics in physics, stressing originality of presentation and suitability for use in students'laboratories, lectures and physics teaching in general. We will also publish more pedagogical papers presenting the achievements of particular teaching methods. In addition, we will continue to publish special sections on particular areas of physics, as well as the annual special section on physics competitions. European Journal of Physics is in good shape. Due to the work of the previous editors and the publisher, the readership is high and growing steadily, and many excellent papers are being submitted and published. I hope that this positive trend for the journal will continue, and I will do my best to keep to this high standard. A few words about myself. I work in the Institute of Physics in Warsaw, Poland. My main research interests are in theoretical quantum optics and I have published about 80 research papers on this topic. For many years I was involved in teaching physics at university and in high school. I am a co-author of a textbook on physics for high-school students and of a problem book in quantum mechanics. For the last ten years, I have been involved in the International Physics Olympiad and over the last few years I have been a member of the Editorial Board of European Journal of Physics.

EDITORIAL: Greetings from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Bhattacharya, P.

2004-04-01

On 1 January, 2004, I assumed the position of Editor-in-Chief of Journal of Physics D: Applied Physics. I will start by saying that I will do my best to justify the confidence of the journal management and publishing staff in my abilities. I was fortunate to have been able to work, as an Editorial Board member, with my predecessor, the previous Editor-in-Chief, Professor Allister Ferguson. Allister has provided a high degree of intellectual stewardship for the journal in the last five years. He has made the job appear a worthy challenge for me. I therefore take this opportunity to thank Allister on behalf of the Editorial Board and publishing staff of the journal. Several other factors contributed to my decision to accept this position. The first is the group of people who actually go about the business of publishing. The Senior Publisher, Nicola Gulley (and her predecessor Sophy Le Masurier); the Managing Editor, Jill Membrey; the Publishing Administrators, Nina Blakesley and Sarah Towell; the Production Editor, Katie Gerrard and their office staff form an amazing group and have managed to make the operation of the journal incredibly efficient. An index of this is the speed with which incoming manuscripts are processed. The average time between the receipt of a manuscript and its web publication, if accepted, is 130 days. This is three to five times shorter than for most other journals. A factor that contributes to this success is a responsive pool of referees that the publishing staff have as a valuable resource. Ultimately, the standard bearers of any journal are the referees. Therefore, a grateful `thank you' is due from all of us at J. Phys. D to all our referees, who diligently perform this honourable task. The Associate Editors of the journal, Professors Lawler, Margaritondo and O'Grady, also provide immense scientific leadership. They help in defining new directions for the journal and in the publishing process. Last, but not least, a remarkable asset of

Mutagenicity of pan residues and gravy from fried meat.

PubMed

Overvik, E; Nilsson, L; Fredholm, L; Levin, O; Nord, C E; Gustafsson, J A

1987-02-01

Lean pork meat was fried with or without the addition of frying-fat at 200 or 250 degrees C. The pan residues were collected by washing the hot pan with boiling water. When producing thickened gravy the water was substituted by a mixture of water and flour, milk and flour or cream and flour. The basic extracts were tested for mutagenicity in Ames' Salmonella test on strain TA98 with the addition of S9 mix. High amounts of mutagenicity were found in all samples. The amounts of mutagenicity in the pan residues were at a comparable level of the amounts found in the meat crusts. Thickening of the gravy caused only small changes in the mutagenicity.

The Pan Zhichang Incident

ERIC Educational Resources Information Center

Yuchen, Zhu

2007-01-01

This article examines why Pan Zhichang, a well-known professor and Ph.D. candidate supervisor at Nanjing University, has repeatedly been accused of plagiarism. It may not be difficult to check whether he has committed plagiarism, but seeking the deeper social and systemic reasons for a person's repeated "negligence" is indeed a…

Brief communication: dental development timing in captive Pan paniscus with comparisons to Pan troglodytes.

PubMed

Bolter, Debra R; Zihlman, Adrienne L

2011-08-01

Dental eruption provides markers of growth and is one component of a chimpanzee's physical development. Dental markers help characterize transitions between life stages, e.g., infant to juvenile. Most of what we know about the timing of development in chimpanzees derives from Pan troglodytes. Much less is known about the sister species, Pan paniscus, with few in captivity and a restricted wild range in central Africa. Here we report on the dental eruption timing for female captive P. paniscus (n = 5) from the Milwaukee and San Diego Zoos whose ages are known and range from birth to age 8.54 years. Some observations were recorded in zoo records on the gingiva during life; others were made at death on the gingiva and on the skeleton. At birth, P. paniscus infants have no teeth emerged. By 0.83 years, all but the deciduous second molars (dm(2) ) (when both upper and lower dentitions are referenced collectively, no super or subscript notation is used) and canines (dc) are emerged. For permanent teeth, results show a sequence polymorphism for an early P4 eruption, not previously described for P. paniscus. Comparisons between P. paniscus and P. troglodytes document absolute timing differences of emergence in upper second incisors (I(2) ), and upper and lower canines (C) and third molars (M3). The genus Pan encompasses variability in growth not previously recognized. These preliminary data suggest that physical growth in captive P. paniscus may be accelerated, a general pattern found in captive P. troglodytes. Copyright © 2011 Wiley-Liss, Inc.

Financial, nonfinancial and editors' conflicts of interest in high-impact biomedical journals.

PubMed

Bosch, Xavier; Pericas, Juan M; Hernández, Cristina; Doti, Pamela

2013-07-01

To assess financial, nonfinancial and editors' conflicts of interest (COI) disclosure policies among the most influential biomedical journals publishing original research. We conducted a cross-sectional study of 399 high-impact biomedical journals in 27 biomedical categories of the Journal Citation Reports (JCR) in December 2011. Information relevant to COI and requirements for disclosures that was publicly available on journal websites was collected. While financial COI disclosures were required by 358 (89.7%) and nonfinancial by 280 (70.2%) journals, 155 (38.8%) required editors' disclosures. Journals in the first decile of the JCR classification scored significantly higher than those in the second decile for all disclosure policies. Ninety (22.6%) journals were published by Elsevier and 59 (14.8%) by Wiley-Blackwell, with Elsevier scoring significantly better in financial disclosure policies (P = 0.022). Clinical journals scored significantly higher than basic journals for all disclosure policies. No differences were observed between open-access (n = 25) and nonopen-access (n = 374) journals for any type of disclosure. Somewhat incoherently, authors' disclosure statements were included in some published manuscript in 57.1% of journals without any COI disclosure policies. Authors' financial COI disclosures were required by about 90% of high-impact clinical and basic journals publishing original research. Unlike recent studies showing a significantly lower prevalence of nonfinancial compared with financial disclosures, the former were required by about 70% of journals, suggesting that editors are increasingly concerned about nonfinancial competing interests. Only 40% of journals required disclosure of editors' COI, in conflict with the recommendations of the most influential editors' associations. © 2013 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.

Payments by US pharmaceutical and medical device manufacturers to US medical journal editors: retrospective observational study

PubMed Central

Bell, Chaim M; Matelski, John J; Detsky, Allan S; Cram, Peter

2017-01-01

Objective To estimate financial payments from industry to US journal editors. Design Retrospective observational study. Setting 52 influential (high impact factor for their specialty) US medical journals from 26 specialties and US Open Payments database, 2014. Participants 713 editors at the associate level and above identified from each journal’s online masthead. Main outcome measures All general payments (eg, personal income) and research related payments from pharmaceutical and medical device manufacturers to eligible physicians in 2014. Percentages of editors receiving payments and the magnitude of such payments were compared across journals and by specialty. Journal websites were also reviewed to determine if conflict of interest policies for editors were readily accessible. Results Of 713 eligible editors, 361 (50.6%) received some (>$0) general payments in 2014, and 139 (19.5%) received research payments. The median general payment was $11 (£8; €9) (interquartile range $0-2923) and the median research payment was $0 ($0-0). The mean general payment was $28 136 (SD $415 045), and the mean research payment was $37 963 (SD $175 239). The highest median general payments were received by journal editors from endocrinology ($7207, $0-85 816), cardiology ($2664, $0-12 912), gastroenterology ($696, $0-20 002), rheumatology ($515, $0-14 280), and urology ($480, $90-669). For high impact general medicine journals, median payments were $0 ($0-14). A review of the 52 journal websites revealed that editor conflict of interest policies were readily accessible (ie, within five minutes) for 17/52 (32.7%) of journals. Conclusions Industry payments to journal editors are common and often large, particularly for certain subspecialties. Journals should consider the potential impact of such payments on public trust in published research. PMID:29074628

panMetaDocs, eSciDoc, and DOIDB - an infrastructure for the curation and publication of file-based datasets for 'GFZ Data Services'

NASA Astrophysics Data System (ADS)

Ulbricht, Damian; Elger, Kirsten; Bertelmann, Roland; Klump, Jens

2016-04-01

With the foundation of DataCite in 2009 and the technical infrastructure installed in the last six years it has become very easy to create citable dataset DOIs. Nowadays, dataset DOIs are increasingly accepted and required by journals in reference lists of manuscripts. In addition, DataCite provides usage statistics [1] of assigned DOIs and offers a public search API to make research data count. By linking related information to the data, they become more useful for future generations of scientists. For this purpose, several identifier systems, as ISBN for books, ISSN for journals, DOI for articles or related data, Orcid for authors, and IGSN for physical samples can be attached to DOIs using the DataCite metadata schema [2]. While these are good preconditions to publish data, free and open solutions that help with the curation of data, the publication of research data, and the assignment of DOIs in one software seem to be rare. At GFZ Potsdam we built a modular software stack that is made of several free and open software solutions and we established 'GFZ Data Services'. 'GFZ Data Services' provides storage, a metadata editor for publication and a facility to moderate minted DOIs. All software solutions are connected through web APIs, which makes it possible to reuse and integrate established software. Core component of 'GFZ Data Services' is an eSciDoc [3] middleware that is used as central storage, and has been designed along the OAIS reference model for digital preservation. Thus, data are stored in self-contained packages that are made of binary file-based data and XML-based metadata. The eSciDoc infrastructure provides access control to data and it is able to handle half-open datasets, which is useful in embargo situations when a subset of the research data are released after an adequate period. The data exchange platform panMetaDocs [4] makes use of eSciDoc's REST API to upload file-based data into eSciDoc and uses a metadata editor [5] to annotate the files

"Clones," Codes, and Conflicts of Interest in Cartooning: Cartoonists and Editors Look at Ethics.

ERIC Educational Resources Information Center

Riffe, Daniel; And Others

A study examined differences between political cartoonists and op-ed page editors on both traditional ethical issues (such as conflicts of interest) and the special, style-related concerns of editorial cartoonists. Hypotheses proposed were that editors and cartoonists (1) would condemn "cloning" or copying, reflecting an ethical…

PanDA for COMPASS at JINR

NASA Astrophysics Data System (ADS)

Petrosyan, A. Sh.

2016-09-01

PanDA (Production and Distributed Analysis System) is a workload management system, widely used for data processing at experiments on Large Hadron Collider and others. COMPASS is a high-energy physics experiment at the Super Proton Synchrotron. Data processing for COMPASS runs locally at CERN, on lxbatch, the data itself stored in CASTOR. In 2014 an idea to start running COMPASS production through PanDA arose. Such transformation in experiment's data processing will allow COMPASS community to use not only CERN resources, but also Grid resources worldwide. During the spring and summer of 2015 installation, validation and migration work is being performed at JINR. Details and results of this process are presented in this paper.

Authors, editors, and the signs, symptoms and causes of plagiarism.

PubMed

Shashok, Karen

2011-07-01

Plagiarism and inadequate citing appear to have reached epidemic proportions in research publication. This article discusses how plagiarism is defined and suggests some possible causes for the increase in the plagiarism disease. Most editors do not have much tolerance for text re-use with inadequate citation regardless of reasons why words are copied from other sources without correct attribution. However, there is now some awareness that re-use of words in research articles to improve the writing or "the English" (which has become a common practice) should be distinguished from intentional deceit for the purpose of stealing other authors' ideas (which appears to remain a very rare practice). Although it has become almost as easy for editors to detect duplicate text as it is for authors to re-use text from other sources, editors often fail to consider the reasons why researchers resort to this strategy, and tend to consider any text duplication as a symptom of serious misconduct. As a result, some authors may be stigmatized unfairly by being labeled as plagiarists. The article concludes with practical advice for researchers on how to improve their writing and citing skills and thus avoid accusations of plagiarism.

Authors, editors, and the signs, symptoms and causes of plagiarism

PubMed Central

Shashok, Karen

2011-01-01

Plagiarism and inadequate citing appear to have reached epidemic proportions in research publication. This article discusses how plagiarism is defined and suggests some possible causes for the increase in the plagiarism disease. Most editors do not have much tolerance for text re-use with inadequate citation regardless of reasons why words are copied from other sources without correct attribution. However, there is now some awareness that re-use of words in research articles to improve the writing or “the English” (which has become a common practice) should be distinguished from intentional deceit for the purpose of stealing other authors’ ideas (which appears to remain a very rare practice). Although it has become almost as easy for editors to detect duplicate text as it is for authors to re-use text from other sources, editors often fail to consider the reasons why researchers resort to this strategy, and tend to consider any text duplication as a symptom of serious misconduct. As a result, some authors may be stigmatized unfairly by being labeled as plagiarists. The article concludes with practical advice for researchers on how to improve their writing and citing skills and thus avoid accusations of plagiarism. PMID:21957412

An electronic pan/tilt/zoom camera system

NASA Technical Reports Server (NTRS)

Zimmermann, Steve; Martin, H. Lee

1991-01-01

A camera system for omnidirectional image viewing applications that provides pan, tilt, zoom, and rotational orientation within a hemispherical field of view (FOV) using no moving parts was developed. The imaging device is based on the effect that from a fisheye lens, which produces a circular image of an entire hemispherical FOV, can be mathematically corrected using high speed electronic circuitry. An incoming fisheye image from any image acquisition source is captured in memory of the device, a transformation is performed for the viewing region of interest and viewing direction, and a corrected image is output as a video image signal for viewing, recording, or analysis. As a result, this device can accomplish the functions of pan, tilt, rotation, and zoom throughout a hemispherical FOV without the need for any mechanical mechanisms. A programmable transformation processor provides flexible control over viewing situations. Multiple images, each with different image magnifications and pan tilt rotation parameters, can be obtained from a single camera. The image transformation device can provide corrected images at frame rates compatible with RS-170 standard video equipment.

From the desk of the Editor-in-Chief

NASA Astrophysics Data System (ADS)

Hei, Tom K.

2015-07-01

Life Sciences in Space Research had a prominent presence at the International Congress of Radiation Research (ICRR) meeting held in Kyoto, Japan from May 25th-29th, with seven of the eleven editors attending the meeting. A journal booth was also put up at the pre-ICRR satellite meeting on Space Radiation and Heavy Ions in Therapy (SRHITS) held a few days earlier in Osaka. Since the inception of LSSR last year, the editors and publisher have promoted the journal at a number of major conferences including COSPAR 2014 in Moscow, the annual meeting of the Radiation Research Society and the NASA Space Radiation Investigators Meeting. These efforts have increased awareness of the journal among investigators in space life sciences and related fields. The number of monthly downloads of articles from the journal website averages 2000, a respectable number for a brand new journal.

Photodegradation inhibitors for polyacrylonitrile/Ag (PAN/Ag) films. Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sergides, C.A.; Chughtai, A.R.; Smith, D.M.

1985-09-01

Three types of UV stabilizers have been investigated for the photostabilization of PAN/Ag films. First, the effect of UV-absorber stabilizers, like the hydrohybenzophenone derivatives (UVINUL SERIES, BASF) absorbing UV radiation in the same region as PAN, was studied. Such additives generally had little effect, while in some cases, photodegradation of PAN was enhanced because of photosensitization. Second, the effect of quencher stabilizers like nickel chelate complexes (Irgastab 2002, CIBA-GEIGY) on the photodegradation of PAN/Ag films was examined. They resulted in marked decreases in the photodegradation of the polymer. Thirdly, antioxidant stabilizers, such as 2,6-di-tert-butyl-4-methylphenol derivatives (Irganox 1010, CIBA-GEIGY), were studiedmore » and also found to have a significant inhibiting effect on the photodegradation of PAN. Increasing the concentration of an effective stabilizer was observed to further decrease the photodegradation. The stabilizer concentration was kept generally low, and a combination of 1% wt antioxidant (Irganox 1010) and 0.5% wt quencher (Irgastab 2002) proved to be optimum. Irganox 1010 and Irgastab 2002 in separate preliminary experiments (in the absence of the polymer) were found to be stable to ultraviolet radiation of air mass one (WG 305).« less

Wintertime peroxyacetyl nitrate (PAN) in the megacity Beijing: role of photochemical and meteorological processes.

PubMed

Zhang, Hualong; Xu, Xiaobin; Lin, Weili; Wang, Ying

2014-01-01

Previous measurements of peroxyacetyl nitrate (PAN) in Asian megacities were scarce and mainly conducted for relative short periods in summer. Here, we present and analyze the measurements of PAN, O3, NO(x), etc., made at an urban site (CMA) in Beijing from 25 January to 22 March 2010. The hourly concentration of PAN averaged 0.70 x 10(-9) mol/mol (0.23 x 10(-9) -3.51 x 10(-9) mol/mol) and was well correlated with that of NO2 but not O3, indicating that the variations of the winter concentrations of PAN and 03 in urban Beijing are decoupled with each other. Wind conditions and transport of air masses exert very significant impacts on O3, PAN, and other species. Air masses arriving at the site originated either from the boundary layer over the highly polluted N-S-W sector or from the free troposphere over the W-N sector. The descending free-tropospheric air was rich in O3, with an average PAN/O3 ratio smaller than 0.031, while the boundary layer air over the polluted sector contained higher levels of PAN and primary pollutants, with an average PAN/O3 ratio of 0.11. These facts related with transport conditions can well explain the observed PAN-O3 decoupling. Photochemical production is important to PAN in the winter over Beijing. The concentration of the peroxyacetyl (PA) radical was estimated to be in the range of 0.0014 x 10(-12) -0.0042 x 10(-12) mol/mol. The contributions of the formation reaction and thermal decomposition to PAN's variation were calculated and found to be significant even in the colder period in air over Beijing, with the production exceeding the decomposition.

Are Editors Out of the Tenure Process?

ERIC Educational Resources Information Center

Howard, Jennifer

2007-01-01

University presses have complained for years that tenure committees unfairly expect their editors to be arbiters of what counts as tenure-worthy work. At the same time, the presses have been caught in a business-side squeeze between dwindling sales (and shrinking subsidies) and the ever-greater pressure on scholars to publish. In this article, the…

Computational pan-genomics: status, promises and challenges.

PubMed

2018-01-01

Many disciplines, from human genetics and oncology to plant breeding, microbiology and virology, commonly face the challenge of analyzing rapidly increasing numbers of genomes. In case of Homo sapiens, the number of sequenced genomes will approach hundreds of thousands in the next few years. Simply scaling up established bioinformatics pipelines will not be sufficient for leveraging the full potential of such rich genomic data sets. Instead, novel, qualitatively different computational methods and paradigms are needed. We will witness the rapid extension of computational pan-genomics, a new sub-area of research in computational biology. In this article, we generalize existing definitions and understand a pan-genome as any collection of genomic sequences to be analyzed jointly or to be used as a reference. We examine already available approaches to construct and use pan-genomes, discuss the potential benefits of future technologies and methodologies and review open challenges from the vantage point of the above-mentioned biological disciplines. As a prominent example for a computational paradigm shift, we particularly highlight the transition from the representation of reference genomes as strings to representations as graphs. We outline how this and other challenges from different application domains translate into common computational problems, point out relevant bioinformatics techniques and identify open problems in computer science. With this review, we aim to increase awareness that a joint approach to computational pan-genomics can help address many of the problems currently faced in various domains. © The Author 2016. Published by Oxford University Press.

Monoclonal antibodies to the equine CD2 T lymphocyte marker, to a pan-granulocyte/monocyte marker and to a unique pan-B lymphocyte marker.

PubMed

Tumas, D B; Brassfield, A L; Travenor, A S; Hines, M T; Davis, W C; McGuire, T C

1994-12-01

Murine monoclonal antibodies, HB88A, B29A and DH59B separately identify the CD2 T lymphocyte molecule, a unique pan-B lymphocyte surface marker and a pan-granulocyte/monocyte surface molecule, respectively, in the horse. Specificity was shown by two-color immunofluorescent flow cytometry and immunofluorescent microscopy. MAb HB88A reacted with a 52 kDa pan-T lymphocyte molecule present on 75% +/- 7 of peripheral blood lymphocytes (PBL) (n = 15 horses). It also reacted with lymphocytes restricted to T lymphocyte dependent areas of lymph node and spleen. Specificity of mAb HB88A to CD2 was demonstrated by its reactivity to COS7 cells which expressed a transfected 1.5 kb equine lymphocyte c-DNA clone having 77.5% overall sequence homology with human CD2 c-DNA. MAb B29A reacted with a pan-B lymphocyte specific cell surface complex, 143, 72, 50, 40, 27 and 14.5 kDa, present on 19% +/- 7 of PBL (n = 15 horses). This complex has not been described in the horse or other species. MAb DH59B reacted with a 96 kDa pan-granulocyte/monocyte specific surface protein and identified macrophages and Kupffer cells in equine tissue sections. Together these mAbs can be used to identify and quantitate the major constituents of equine leukocytes.

The Pan-STARRS PS1 Image Processing Pipeline

NASA Astrophysics Data System (ADS)

Magnier, E.

The Pan-STARRS PS1 Image Processing Pipeline (IPP) performs the image processing and data analysis tasks needed to enable the scientific use of the images obtained by the Pan-STARRS PS1 prototype telescope. The primary goals of the IPP are to process the science images from the Pan-STARRS telescopes and make the results available to other systems within Pan-STARRS. It also is responsible for combining all of the science images in a given filter into a single representation of the non-variable component of the night sky defined as the "Static Sky". To achieve these goals, the IPP also performs other analysis functions to generate the calibrations needed in the science image processing, and to occasionally use the derived data to generate improved astrometric and photometric reference catalogs. It also provides the infrastructure needed to store the incoming data and the resulting data products. The IPP inherits lessons learned, and in some cases code and prototype code, from several other astronomy image analysis systems, including Imcat (Kaiser), the Sloan Digital Sky Survey (REF), the Elixir system (Magnier & Cuillandre), and Vista (Tonry). Imcat and Vista have a large number of robust image processing functions. SDSS has demonstrated a working analysis pipeline and large-scale databasesystem for a dedicated project. The Elixir system has demonstrated an automatic image processing system and an object database system for operational usage. This talk will present an overview of the IPP architecture, functional flow, code development structure, and selected analysis algorithms. Also discussed is the HW highly parallel HW configuration necessary to support PS1 operational requirements. Finally, results are presented of the processing of images collected during PS1 early commissioning tasks utilizing the Pan-STARRS Test Camera #3.

Regulatory logic of pan-neuronal gene expression in C. elegans

PubMed Central

Stefanakis, Nikolaos; Carrera, Ines; Hobert, Oliver

2015-01-01

While neuronal cell types display an astounding degree of phenotypic diversity, most if not all neuron types share a core panel of terminal features. However, little is known about how pan-neuronal expression patterns are genetically programmed. Through an extensive analysis of the cis-regulatory control regions of a battery of pan-neuronal C.elegans genes, including genes involved in synaptic vesicle biology and neuropeptide signaling, we define a common organizational principle in the regulation of pan-neuronal genes in the form of a surprisingly complex array of seemingly redundant, parallel-acting cis-regulatory modules that direct expression to broad, overlapping domains throughout the nervous system. These parallel-acting cis-regulatory modules are responsive to a multitude of distinct trans-acting factors. Neuronal gene expression programs therefore fall into two fundamentally distinct classes. Neuron type-specific genes are generally controlled by discrete and non-redundantly acting regulatory inputs, while pan-neuronal gene expression is controlled by diverse, coincident and seemingly redundant regulatory inputs. PMID:26291158

BRDF of Salt Pan Regolith Samples

NASA Technical Reports Server (NTRS)

Georgiev, Georgi T.; Gatebe, Charles K.; Butler, James J.; King, Michael D.

2008-01-01

Laboratory Bi-directional Reflectance Distribution Function (BRDF) measurements of salt pan regolith samples are presented in this study in an effort to understand the role of spatial and spectral variability of the natural biome. The samples were obtained from Etosha Pan, Namibia (19.20 deg S, 15.93 deg E, alt. 1100 m). It is shown how the BRDF depends on the measurement geometry - incident and scatter angles and on the sample particle sizes. As a demonstration of the application of the results, airborne BRDF measurements acquires with NASA's Cloud Absorption Radiometer (CAR) over the same general site where the regolith samples were collected are compared with the laboratory results. Good agreement between laboratory measured and field measured BRDF is reported.

How is research publishing going to progress in the next 20 years?: transcription of session for editors, associate editors, publishers and others with an interest in scientific publishing held at IADR meeting in Seattle on Wednesday, 20 March 2013.

PubMed

Eaton, Kenneth A; Rex Holland, G; Giannobile, William V; Hancocks, Stephen; Robinson, Peter G; Lynch, Christopher D

2014-03-01

On March 20th 2013, a one-hour session for Editors, Associate Editors, Publishers and others with an interest in scientific publishing was held at the IADR International Session in Seattle. Organised by Kenneth Eaton and Christopher Lynch (Chair and Secretary, respectively, of the British Dental Editors Forum), the meeting sought to bring together leading international experts in dental publishing, as well as authors, reviewers and students engaged in research. The meeting was an overwhelming success, with more than 100 attendees. A panel involving four leading dental editors led a discussion on anticipated developments in publishing dental research with much involvement and contribution from audience members. This was the third such meeting held at the IADR for Editors, Associate Editors, Publishers and others with an interest in scientific publishing. A follow-up session will take place in Cape Town on 25 June 2014 as part of the annual IADR meeting. The transcript of the Seattle meeting is reproduced in this article. Where possible speakers are identified by name. At the first time of mention their role/position is also stated, thereafter only their name appears. We are grateful to Stephen Hancocks Ltd. for their generous sponsorship of this event. For those who were not able to attend the authors hope this article gives a flavour of the discussions and will encourage colleagues to attend future events. Involvement is open to Editors, Associate Editors, Publishers and others with an interest in scientific publishing. It is a very open group and all those with an interest will be welcome to join in. Copyright © 2014 Elsevier Ltd. All rights reserved.

Measurements of peroxyacetyl nitrate (PAN) and NO2 at the South Pacific Ocean

NASA Astrophysics Data System (ADS)

Yeon, J.; Song, D.; Lee, J. S.; Rhee, T. S.; Park, K.; Lee, G.

2014-12-01

We measured peroxyacetyl nitrate (PAN) and NO2 in remote marine boundary area during the SHIPPO (Shipborne Pole to Pole Observation). The measurements were made on the R/V Araon from Christ church, New Zealand to Gwangyang, South Korea along the western Pacific Ocean from March 30th to April 25th, 2014. Both PAN and NO2 were analyzed every 2 minute by a fast chromatograph with luminol-based chemiluminescence detection. In order to improve their detection limits, random noise from PMT has been successfully reduced by ensembled chromatograms with every 30 samples. Additionally, we replaced Nylon membrane surface with reflective aluminum surface and applied the new Luminol solution, which enhanced the signals significantly with detection limits of 6 pptv and 40 ppbv for PAN and NO2, respectively. Average concentrations of PAN and NO2 were 8 pptv for PAN and 80 pptv for NO2 during the experiment. The back trajectory analysis showed that the directly influenced air masses from anthropogenic activities were rare except the latitudes higher than 20°N. Relatively good correlations between PAN and NO2 were consistently observed, while PAN and O3 were not clearly correlated except in the air masses recently originated from land masses.

IN DEFENSE OF ECORISK ASSESSMENT (LETTER TO EDITOR)

EPA Science Inventory

Dear Editor: We are writing to convey a more accurate portrayal of the status of ecological ("environmental" in Europe) risk assessment that was presented in the recent article by M. Power and L.S. McCarty (Fallacies in Ecological Risk Assessment Practices," August 1997, pp 370A-...

Contributions of burner, pan, meat and salt to PM emission during grilling.

PubMed

Amouei Torkmahalleh, Mehdi; Ospanova, Saltanat; Baibatyrova, Aknur; Nurbay, Shynggys; Zhanakhmet, Gulaina; Shah, Dhawal

2018-07-01

Grilling ground beef meat was conducted in two locations at Nazarbayev University, Kazakhstan. The experiments were designed such that only particles from beef meat were isolated. A similar experimental protocol was applied at both locations. The average particle number and mass emission rates for grilling pure meat itself (excluding particles from pan and burner) were found to be 9.4 × 10 12 (SD = 7.2 × 10 12 particle min -1 and 7.6 × 10 (SD = 6.3 × 10) mg.min -1 , respectively. The PM emissions (number and mass) from the burner were found to be negligible compared to the pan and meat emissions. Ultrafine particle (UFP) concentrations from the heated pan itself were comparable to those of grilled meat. However, the particle mass concentrations from the pan itself were negligible. Approximately an hour of continuous heating resulted in zero emissions from the pan. Copyright © 2018 Elsevier Inc. All rights reserved.

Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis.

PubMed

Shi, Wanliang; Chen, Jiazhen; Feng, Jie; Cui, Peng; Zhang, Shuo; Weng, Xinhua; Zhang, Wenhong; Zhang, Ying

2014-08-01

Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the treatment of both drug-susceptible and multidrug-resistant tuberculosis (MDR-TB). PZA is a prodrug that is converted to its active form, pyrazinoic acid (POA), by a nicotinamidase/pyrazinamidase encoded by the pncA gene, the mutation of which is the major cause of PZA resistance. Although RpsA (ribosomal protein S1, involved in trans-translation) has recently been shown to be a target of POA/PZA, whole-genome sequencing has identified mutations in the panD gene encoding aspartate decarboxylase in PZA-resistant strains lacking pncA and rpsA mutations. To gain more insight into a possible new target of PZA, we isolated 30 POA-resistant mutants lacking mutations in pncA and rpsA from M. tuberculosis in vitro, and whole-genome sequencing of 3 mutants identified various mutations in the panD gene. Additionally, sequencing analysis revealed that the remaining 27 POA-resistant mutants all harbored panD mutations affecting the C-terminus of the PanD protein, with PanD M117I being the most frequent mutation (24/30, 80%). Conditional overexpression of panD from M. tuberculosis, M. smegmatis or E. coli, or of M. tuberculosis mutant PanD M117I, all conferred resistance to POA and PZA in M. tuberculosis. β-alanine and pantothenate, which are downstream products of PanD, were found to antagonize the antituberculosis activity of POA. In addition, the activity of the M. tuberculosis PanD enzyme was inhibited by POA at therapeutically relevant concentrations in a concentration-dependent manner but was not inhibited by the prodrug PZA or the control compound nicotinamide. These findings suggest that PanD represents a new target of PZA/POA. These results have implications for a better understanding of this peculiar persister drug and for the design of new drugs targeting M. tuberculosis persisters for improved treatment.

PD2P: PanDA Dynamic Data Placement for ATLAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maeno, T.; De, K.; Panitkin, S.

2012-12-13

The PanDA (Production and Distributed Analysis) system plays a key role in the ATLAS distributed computing infrastructure. PanDA is the ATLAS workload management system for processing all Monte-Carlo (MC) simulation and data reprocessing jobs in addition to user and group analysis jobs. The PanDA Dynamic Data Placement (PD2P) system has been developed to cope with difficulties of data placement for ATLAS. We will describe the design of the new system, its performance during the past year of data taking, dramatic improvements it has brought about in the efficient use of storage and processing resources, and plans for the future.

Kepler K2 Campaign 14 search for supernovae using Pan-STARRS

NASA Astrophysics Data System (ADS)

Smartt, S. J.; Smith, K. W.; Rest, A.; Garnavich, P. M.; Tucker, B. E.; Margheim, S.; Kasen, D.; Olling, R.; Shaya, E.; Zenteno, A.; Chambers, K. C.; Huber, M. E.; Flewelling, H.; Magnier, E. A.; Schultz, A.; Lowe, T.; Tonry, J.; Waters, C.; Wright, D. E.; Young, D. R.

2017-06-01

12 transients have been discovered as part of the Kepler K2 Campaign 14 search using the Pan-STARRS telescope augmenting the Pan-STARRS Search for Transients (PSST) http://star.pst.qub.ac.uk/ps1threepi/.

xLPR Sim Editor 1.0 User's Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mariner, Paul E.

2017-03-01

The United States Nuclear Regulatory Commission in cooperation with the Electric Power Research Institute contracted Sandia National Laboratories to develop the framework of a probabilistic fracture mechanics assessment code called xLPR ( Extremely Low Probability of Rupture) Version 2.0 . The purpose of xLPR is to evaluate degradation mechanisms in piping systems at nuclear power plants and to predict the probability of rupture. This report is a user's guide for xLPR Sim Editor 1.0 , a graphical user interface for creating and editing the xLPR Version 2.0 input file and for creating, editing, and using the xLPR Version 2.0 databasemore » files . The xLPR Sim Editor, provides a user - friendly way for users to change simulation options and input values, s elect input datasets from xLPR data bases, identify inputs needed for a simulation, and create and modify an input file for xLPR.« less

Initiation of a pan-genomic research project for Xylella fastidiosa

USDA-ARS?s Scientific Manuscript database

Differences in genomic structure and nucleotide polymorphism among strains form the genetic basis for adaptability of a bacterial species. This can be described by a bacterial pan-genome, which is defined as the full complement of genes in all strains of a species. The pan-genome is composed of a "c...

An investigation of electrochemomechanical actuation of conductive Polyacrylonitrile (PAN) nanofiber composites

NASA Astrophysics Data System (ADS)

Gonzalez, Mark A.; Walter, Wayne W.

2014-03-01

A polymer-based nanofiber composite actuator designed for contractile actuation was fabricated by electrospinning, stimulated by electrolysis, and characterized by electrochemical and mechanical testing to address performance limitations and understand the activation processing effects on actuation performance. Currently, Electroactive polymers (EAPs) have provided uses in sensory and actuation technology, but have either low force output or expand rather than contract, falling short in capturing the natural kinetics and mechanics of muscle needed to provide breakthroughs in the bio-medical and robotic fields. In this study, activated Polyacrylonitrile (PAN) fibers have demonstrated biomimetic functionalities similar to the sarcomere contraction responsible for muscle function. Activated PAN has also been shown to contract and expand by electrolysis when in close vicinity to the anode and cathode, respectively. PAN nanofibers (~500 nm) especially show faster response to changes in environmental pH and improved mechanical properties compared to larger diameter fibers. Tensile testing was conducted to examine changes in mechanical properties between annealing and hydrolysis processing. Voltage driven transient effects of localized pH were examined to address pHdefined actuation thresholds of PAN fibers. Electrochemical contraction rates of the PAN/Graphite composite actuator demonstrated up to 25%/min. Strains of 58.8%, ultimate stresses up to 77.1 MPa, and moduli of 0.21 MPa were achieved with pure PAN nanofiber mats, surpassing mechanical properties of natural muscles. Further improvements, however, to contraction rates and Young's moduli were found essential to capture the function and performance of skeletal muscles appropriately.

Adequacy of authors’ replies to criticism raised in electronic letters to the editor: cohort study

PubMed Central

Delamothe, Tony; Godlee, Fiona; Lundh, Andreas

2010-01-01

Objective To investigate whether substantive criticism in electronic letters to the editor, defined as a problem that could invalidate the research or reduce its reliability, is adequately addressed by the authors. Design Cohort study. Setting BMJ between October 2005 and September 2007. Inclusion criteria Research papers generating substantive criticism in the rapid responses section on bmj.com. Main outcome measures Severity of criticism (minor, moderate, or major) as judged by two editors and extent to which the criticism was addressed by authors (fully, partly, or not) as judged by two editors and the critics. Results A substantive criticism was raised against 105 of 350 (30%, 95% confidence interval 25% to 35%) included research papers, and of these the authors had responded to 47 (45%, 35% to 54%). The severity of the criticism was the same in those papers as in the 58 without author replies (mean score 2.2 in both groups, P=0.72). For the 47 criticisms with replies, there was no relation between the severity of the criticism and the adequacy of the reply, neither as judged by the editors (P=0.88 and P=0.95, respectively) nor by the critics (P=0.83; response rate 85%). However, the critics were much more critical of the replies than the editors (average score 2.3 v 1.4, P<0.001). Conclusions Authors are reluctant to respond to criticisms of their work, although they are not less likely to respond when criticisms are severe. Editors should ensure that authors take relevant criticism seriously and respond adequately to it. PMID:20699306

Payments by US pharmaceutical and medical device manufacturers to US medical journal editors: retrospective observational study.

PubMed

Liu, Jessica J; Bell, Chaim M; Matelski, John J; Detsky, Allan S; Cram, Peter

2017-10-26

Objective  To estimate financial payments from industry to US journal editors. Design  Retrospective observational study. Setting  52 influential (high impact factor for their specialty) US medical journals from 26 specialties and US Open Payments database, 2014. Participants  713 editors at the associate level and above identified from each journal's online masthead. Main outcome measures  All general payments (eg, personal income) and research related payments from pharmaceutical and medical device manufacturers to eligible physicians in 2014. Percentages of editors receiving payments and the magnitude of such payments were compared across journals and by specialty. Journal websites were also reviewed to determine if conflict of interest policies for editors were readily accessible. Results  Of 713 eligible editors, 361 (50.6%) received some (>$0) general payments in 2014, and 139 (19.5%) received research payments. The median general payment was $11 (£8; €9) (interquartile range $0-2923) and the median research payment was $0 ($0-0). The mean general payment was $28 136 (SD $415 045), and the mean research payment was $37 963 (SD $175 239). The highest median general payments were received by journal editors from endocrinology ($7207, $0-85 816), cardiology ($2664, $0-12 912), gastroenterology ($696, $0-20 002), rheumatology ($515, $0-14 280), and urology ($480, $90-669). For high impact general medicine journals, median payments were $0 ($0-14). A review of the 52 journal websites revealed that editor conflict of interest policies were readily accessible (ie, within five minutes) for 17/52 (32.7%) of journals. Conclusions  Industry payments to journal editors are common and often large, particularly for certain subspecialties. Journals should consider the potential impact of such payments on public trust in published research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a

Influence of peroxyacetyl nitrate (PAN) on odd nitrogen in the troposphere and lower stratosphere

NASA Technical Reports Server (NTRS)

Aikin, A. C.; Herman, J. R.; Maier, E. J. R.; Mcquillan, C. J.

1983-01-01

Nonmethane hydrocarbon breakdown in the atmosphere produces aldehydes of which a fraction are transferred into peroxyacetyl nitrates (PAN) in the presence of NO and NO2. Since ethane is destroyed photochemically primarily above 1 km, PAN can be introduced into the upper troposphere and lower stratosphere without the need to be transported from the boundary layer where most hydrocarbons are destroyed and where PAN may be lost due to thermal decomposition and heterogeneous loss. Mixing ratios of ethane in the lower troposphere increase by a factor of 4-8 from equatorial to northern mid-latitudes. This difference is directly translatable into a PAN latitude gradient. At mid-latitudes the concentration of PAN below 20 km is 0.1 ppb comparable to and in some instances larger than predicted HO2NO2 mixing ratios. Like HO2NO2 and HNO3, PAN serves as a reservoir for odd nitrogen.

Evaluation of the tablets' surface flow velocities in pan coaters.

PubMed

Dreu, Rok; Toschkoff, Gregor; Funke, Adrian; Altmeyer, Andreas; Knop, Klaus; Khinast, Johannes; Kleinebudde, Peter

2016-09-01

The tablet pan coating process involves various types of transverse tablet bed motions, ranging from rolling to cascading. To preserve satisfactory results in terms of coating quality after scale-up, understanding the dynamics of pan coating process should be achieved. The aim of this study was to establish a methodology of estimating translational surface velocities of the tablets in a pan coater and to assess their dependence on the drum's filling degree, the pan speed, the presence of baffles and the selected tablet properties in a dry bed system and during coating while varying the drum's filling degree and the pan speed. Experiments were conducted on the laboratory scale and on the pilot scale in side-vented pan coaters. Surface movement of biconvex two-layer tablets was assessed before, during and after the process of active coating. In order to determine the tablets' surface flow velocities, a high-speed video of the tablet surface flow was recorded via a borescope inserted into the coating drum and analysed via a cross-correlation algorithm. The obtained tablet velocity data were arranged in a linear fashion as a function of the coating drum's radius and frequency. Velocity data obtained during coating were close to those of dry tablets after coating. The filling degree had little influence on the tablet velocity profile in a coating drum with baffles but clearly affected it in a coating drum without baffles. In most but not all cases, tablets with a lower static angle of repose had tablet velocity profiles with lower slopes than tablets with higher inter-tablet friction. This particular tablet velocity response can be explained by case specific values of tablet bed's dynamic angle of repose. Copyright © 2016 Elsevier B.V. All rights reserved.

Stone tool production and utilization by bonobo-chimpanzees (Pan paniscus).

PubMed

Roffman, Itai; Savage-Rumbaugh, Sue; Rubert-Pugh, Elizabeth; Ronen, Avraham; Nevo, Eviatar

2012-09-04

Using direct percussion, language-competent bonobo-chimpanzees Kanzi and Pan-Banisha produced a significantly wider variety of flint tool types than hitherto reported, and used them task-specifically to break wooden logs or to dig underground for food retrieval. For log breaking, small flakes were rotated drill-like or used as scrapers, whereas thick cortical flakes were used as axes or wedges, leaving consistent wear patterns along the glued slits, the weakest areas of the log. For digging underground, a variety of modified stone tools, as well as unmodified flint nodules, were used as shovels. Such tool production and utilization competencies reported here in Pan indicate that present-day Pan exhibits Homo-like technological competencies.

Structural Oil Pan With Integrated Oil Filtration And Cooling System

DOEpatents

Freese, V, Charles Edwin

2000-05-09

An oil pan for an internal combustion engine includes a body defining a reservoir for collecting engine coolant. The reservoir has a bottom and side walls extending upwardly from the bottom to present a flanged lip through which the oil pan may be mounted to the engine. An oil cooler assembly is housed within the body of the oil pan for cooling lubricant received from the engine. The body includes an oil inlet passage formed integrally therewith for receiving lubricant from the engine and delivering lubricant to the oil cooler. In addition, the body also includes an oil pick up passage formed integrally therewith for providing fluid communication between the reservoir and the engine through the flanged lip.

LETTER TO EDITOR ON ARTICLE "ARSENIC MEANS BUSINESS"

EPA Science Inventory

The letter to the editor was written to point out that different forms of arsenic are found in source waters and that the technologies listed in the article such as POU RO will not necessarily be effective on all waters. The letter pointed out that most technologies are more eff...

Particle size fraction -Response: Letter to the Editors

EPA Science Inventory

To the Editors: We, the undersigned, would like to comment on the article by Cho et al. (Cho et al. 2009), which was published in the November 2009 issue (volume 11, number 11, page 1682-1689) of Environmental Health Perspectives. We read the paper with great interest as the dis...

Satellite-derived pan-Arctic melt onset dataset, 2000-2009

NASA Astrophysics Data System (ADS)

Wang, L.; Derksen, C.; Howell, S.; Wolken, G. J.; Sharp, M. J.; Markus, T.

2009-12-01

The SeaWinds Scatterometer on QuikSCAT (QS) has been in orbit for over a decade since its launch in June 1999. Due to its high sensitivity to the appearance of liquid water in snow and day/night all weather capability, QS data have been successfully used to detect melt onset and melt duration for various elements of the cryosphere. These melt datasets are especially useful in the polar regions where the application of imagery from optical sensors is hindered by polar nights and frequent cloud cover. In this study, we generate a pan-Arctic, pan-cryosphere melt onset dataset by combining estimates from previously published algorithms optimized for individual cryospheric elements and applied to QS and Special Sensor Microwave Imager (SSM/I) data for the northern high latitude land surface, ice caps, large lakes, and sea ice. Comparisons of melt onset along the boundaries between different components of the cryosphere show that in general the integrated dataset provides consistent and spatially coherent melt onset estimates across the pan-Arctic. We present the climatology and the anomaly patterns in melt onset during 2000-2009, and identify synoptic-scale linkages between atmospheric conditions and the observed patterns. We also investigate the possible trends in melt onset in the pan-Arctic during the 10-year period.

TCGA's Pan-Cancer Efforts and Expansion to Include Whole Genome Sequence - TCGA

Cancer.gov

Carolyn Hutter, Ph.D., Program Director of NHGRI's Division of Genomic Medicine, discusses the expansion of TCGA's Pan-Cancer efforts to include the Pan-Cancer Analysis of Whole Genomes (PAWG) project.

A Portable Burn Pan for the Disposal of Excess Propellants

DTIC Science & Technology

2016-11-01

pan caused by radiant heat .............................. 39 11 Wet propellant (12-0 kg burn) and dry propellant (460 kg) burn residues...43 13 Graph of component temperatures during an ATU burn pan test ......................................... 45 14 IR Camera thermal...than anticipated. Dr. Packer also fully embraced the concept, requesting background reports and papers as well as test reports from all the

Beacon Editor: Capturing Signal Transduction Pathways Using the Systems Biology Graphical Notation Activity Flow Language.

PubMed

Elmarakeby, Haitham; Arefiyan, Mostafa; Myers, Elijah; Li, Song; Grene, Ruth; Heath, Lenwood S

2017-12-01

The Beacon Editor is a cross-platform desktop application for the creation and modification of signal transduction pathways using the Systems Biology Graphical Notation Activity Flow (SBGN-AF) language. Prompted by biologists' requests for enhancements, the Beacon Editor includes numerous powerful features for the benefit of creation and presentation.

Parting messages from current and former editors of the Journal of Andrology.

PubMed

Bartke, Andrzej; Orgebin-Crist, Marie-Claire; Desjardins, Claude; Lewis, Ron; Tindall, Don; Hamilton, David W; Pryor, Jon L; Schlegel, Peter N; Hardy, Matthew P; Burnett, Arthur L Bud; Darney, Sally P; Sandlow, Jay

2012-01-01

The proposal to produce this final commemorative issue for the Journal of Andrology arose during our regular discussions as current editors soon after it was announced that the Journal would complete its own life course and merge into a new publication (to be named Andrology) with the International Journal of Andrology. We considered the momentous occasion to be one that should be celebrated with an enduring tribute in recognition of the Journal's exceptional 33-year existence. Among the various contributions sought for inclusion in this issue, we envisioned an article assembling collected short essays from all living former editors drawing on notable events and highlights, if not less well-known challenges and successes arising during their editorship eras. We thought that any such production of musings, viewpoints, and most of all words of wisdom from those who have had major roles in the direction and accomplishments of the Journal would offer an illuminating read for the society's members and friends and provide all readers another venue to share in and enjoy the Journal's great history. We are enthralled to have gathered these collections, all personal compositions of the former editors-in-chief, and for their effort that has helped us complete this special endeavor we express to them our tremendous gratitude. Serving as the Journal's last editors, we are also grateful to contribute our essay at the very end as part of this joyous chronicle.

May 2018 Letters to the Editor-in-Chief.

PubMed

2018-05-01

Letters to the Editor-in-Chief of JOSPT as follows: "Regarding 'Unraveling the Mechanisms of Manual Therapy'" with Authors' Response "The Use of a Broad or Narrow Definition of Injury in Dance Surveillance" with Authors' Response J Orthop Sports Phys Ther 2018;48(5):421-424. doi:10.2519/jospt.2018.0201.

EDITORIAL: Outgoing Editor-in-Chief Outgoing Editor-in-Chief

NASA Astrophysics Data System (ADS)

Hauptmann, Peter

2012-01-01

I started in 2002 as Editor-in-Chief of a well established journal—MST (Measurement Science and Technology). It was a time when modern means of communication offered new opportunities for the scientific community—for all scientists and engineers whether at universities, in industry or at other institutions—to access better quality information in a shorter time. This development helped us to be more efficient in our daily scientific work and to anticipate new trends faster than before. A flood of information was created by different search engines. A few online journals or journals published in emerging countries with a similar profile to MST appeared on the market. MST had to provide new answers in response to these developments. In 2002 I postulated two requirements to the journal. Firstly, the publisher has to be up to date. My impression over the years has been that IOPP is excellently organized. That has made it easier for the board members and all our reviewers to concentrate on the scientific aspects of our input to the journal. During all my visits to Bristol or my contacts with the IOPP staff I always met very professional and enthusiastic staff members. They have not only supported and encouraged the ideas and initiatives of the Editorial Board members, but they have also worked hard on establishing one of the most effective journal operations in the field of measurement science and technology. Many authors are well aware of this. Thus I am able to declare that the first requirement for a successful journal has been met. Secondly, the scientific level has to be high and the journal should attract readers from all over the world. This task was the responsibility of the Editorial Board members and of myself. Our strategy was on the one hand to ensure continuity in MST but on the other hand to be open to new trends and developments. Examples of these new aspects of the journal are fields like micro- and nanometrology, measurement techniques for

Evaluation of chemopreventive effects of betel leaf on the genotoxicity of pan masala.

PubMed

Trivedi, A H; Patel, R K; Rawal, U M; Adhvaryu, S G; Balar, D B

1994-01-01

The antigenotoxic effect of the aqueous extract of betel leaf (BL-ext.) against the pan masala was tested with the help of cytogenetic endpoints like chromosome aberration (CA) and sister chromatid exchange (SCE) utilizing Chinese hamster ovary (CHO) cells. Compared to the cultures treated with aqueous extract of pan masala alone, a reduction in CA and SCE frequencies in CHO cells was observed following a combined treatment with pan masala (with or without tobacco) extract and BL-ext. The protective effect of BL-ext. against the genomic damage caused by pan masala was statistically significant only after treating the cells for a longer period.

A Generic Metadata Editor Supporting System Using Drupal CMS

NASA Astrophysics Data System (ADS)

Pan, J.; Banks, N. G.; Leggott, M.

2011-12-01

Metadata handling is a key factor in preserving and reusing scientific data. In recent years, standardized structural metadata has become widely used in Geoscience communities. However, there exist many different standards in Geosciences, such as the current version of the Federal Geographic Data Committee's Content Standard for Digital Geospatial Metadata (FGDC CSDGM), the Ecological Markup Language (EML), the Geography Markup Language (GML), and the emerging ISO 19115 and related standards. In addition, there are many different subsets within the Geoscience subdomain such as the Biological Profile of the FGDC (CSDGM), or for geopolitical regions, such as the European Profile or the North American Profile in the ISO standards. It is therefore desirable to have a software foundation to support metadata creation and editing for multiple standards and profiles, without re-inventing the wheels. We have developed a software module as a generic, flexible software system to do just that: to facilitate the support for multiple metadata standards and profiles. The software consists of a set of modules for the Drupal Content Management System (CMS), with minimal inter-dependencies to other Drupal modules. There are two steps in using the system's metadata functions. First, an administrator can use the system to design a user form, based on an XML schema and its instances. The form definition is named and stored in the Drupal database as a XML blob content. Second, users in an editor role can then use the persisted XML definition to render an actual metadata entry form, for creating or editing a metadata record. Behind the scenes, the form definition XML is transformed into a PHP array, which is then rendered via Drupal Form API. When the form is submitted the posted values are used to modify a metadata record. Drupal hooks can be used to perform custom processing on metadata record before and after submission. It is trivial to store the metadata record as an actual XML file

Real-Time Penetrating Particle Analyzer (PAN)

NASA Astrophysics Data System (ADS)

Wu, X.; Ambrosi, G.; Bertucci, B.

2018-02-01

The PAN can measure penetrating particles with great precision to study energetic particles, solar activities, and the origin and propagation of cosmic rays. The real-time monitoring of penetrating particles is crucial for deep space human travel.

Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action.

PubMed

Barnard, Leanne; Mostert, Konrad J; van Otterlo, Willem A L; Strauss, Erick

2018-05-11

Pantothenamides (PanAms) are analogues of pantothenate, the biosynthetic precursor of coenzyme A (CoA), and show potent antimicrobial activity against several bacteria and the malaria parasite in vitro. However, pantetheinase enzymes that normally degrade pantetheine in human serum also act on the PanAms, thereby reducing their potency. In this study, we designed analogues of the known antibacterial PanAm N-heptylpantothenamide (N7-Pan) to be resistant to pantetheinase by using three complementary structural modification strategies. We show that, while two of these are effective in imparting resistance, the introduced modifications have an impact on the analogues' interaction with pantothenate kinase (PanK, the first CoA biosynthetic enzyme), which acts as a metabolic activator and/or target of the PanAms. This, in turn, directly affects their mode of action. Importantly, we discover that the phosphorylated version of N7-Pan shows pantetheinase resistance and antistaphylococcal activity, providing a lead for future studies in the ongoing search of PanAm analogues that show in vivo efficacy.

nu/TPU -- A DEC TPU compatible editor for UNIX

NASA Astrophysics Data System (ADS)

Rehan, S. C.

nu/TPU is a fully programmable text processing utility compatible with the TPU system found on VMS systems. People used to using TPU or EDT on the former Starlink VAX/VMS service will find that nu/TPU is very similar to these editors.

Horatio Alger in the Newsroom: Social Origins of American Editors

ERIC Educational Resources Information Center

Hart, Jack R.

1976-01-01

Concludes that American newspaper editors of the late nineteenth and early twentieth centuries came from elite social backgrounds, which is contrary to the rags-to-riches image fostered by previous historians. (RB)

PROGRAMMABLE DISPLAY PUSHBUTTON LEGEND EDITOR

NASA Technical Reports Server (NTRS)

Busquets, A. M.

1994-01-01

The Programmable Display Pushbutton (PDP) is a pushbutton device available from Micro Switch which has a programmable 16 x 35 matrix of LEDs on the pushbutton surface. Any desired legends can be displayed on the PDPs, producing user-friendly applications which greatly reduce the need for dedicated manual controls. Because the PDP can interact with the operator, it can call for the correct response before transmitting its next message. It is both a simple manual control and a sophisticated programmable link between the operator and the host system. The Programmable Display Pushbutton Legend Editor, PDPE, is used to create the LED displays for the pushbuttons. PDPE encodes PDP control commands and legend data into message byte strings sent to a Logic Refresh and Control Unit (LRCU). The LRCU serves as the driver for a set of four PDPs. The legend editor (PDPE) transmits to the LRCU user specified commands that control what is displayed on the LED face of the individual pushbuttons. Upon receiving a command, the LRCU transmits an acknowledgement that the message was received and executed successfully. The user then observes the effect of the command on the PDP displays and decides whether or not to send the byte code of the message to a data file so that it may be called by an applications program. The PDPE program is written in FORTRAN for interactive execution. It was developed on a DEC VAX 11/780 under VMS. It has a central memory requirement of approximately 12800 bytes. It requires four Micro Switch PDPs and two RS-232 VAX 11/780 terminal ports. The PDPE program was developed in 1985.

Most Business Editors Find Journalism Graduates Still Unprepared

ERIC Educational Resources Information Center

Pardue, Mary Jane

2014-01-01

In 2002, a study was published in "Newspaper Research Journal" that explored the preparedness of graduating journalism students to cover business news. In 2012, a follow-up survey of business editors at the nation's daily newspapers was done to see whether progress had been made in the training of journalism students for the…

Publishing in Educational Psychology Journals: Comments from Editors

ERIC Educational Resources Information Center

Nihalani, Priya K.; Mayrath, Michael C.

2008-01-01

The following paper emphasizes the importance of publishing and learning how to publish in educational psychology journals. We have compiled a set of recommendations based on advice from editors in the field and several other sources on how to publish. Additionally, this paper provides a step-by-step guide that graduate students and junior faculty…

Uniform requirements for manuscripts submitted to biomedical journals. International Committee of Medical Journal Editors.

PubMed Central

1994-01-01

In the 13 years since it was first published the "Uniform requirements for manuscripts submitted to biomedical journals" (the Vancouver style), developed by the International Committee of Medical Journal Editors, has been widely accepted by both authors and editors; over 400 journals have stated that they will consider manuscripts that conform to its requirements. This is the fourth edition of the "Uniform requirements." PMID:8287338

"A Constant Transit of Finding": Fantasy as Realisation in "Pan's Labyrinth"

ERIC Educational Resources Information Center

Clark, Roger; McDonald, Keith

2010-01-01

This article considers Guillermo Del Toro's "Pan's Labyrinth" as a text which utilises key codes and conventions of children's literature as a means of encountering the trauma of Fascism. The article begins by placing "Pan's Labyrinth" at a contextual crossroads involving fairy tale and a Spanish cinematic tradition and…

EDITORIAL: Message from the Editor

NASA Astrophysics Data System (ADS)

Thomas, Paul

2009-01-01

Plasmaphysik, Germany) V. Philipps (Forschungszentrum Juelich, Germany) S. Zweben (Princeton Plasma Physics Laboratory, USA) Y. Hirano (National Institute of Advanced Industrial Science and Technology, Japan) Y. Takase (Tokyo University, Japan) In addition there is a group of several hundred referees who have helped us in the past year to maintain the high scientific standard of Nuclear Fusion. At the end of this issue we give the full list of all referees for 2008. Our thanks to them! Authors The winner of the 2007 award was Clemente Angioni for the paper entitled `Density response to central electron heating: theoretical investigations and experimental observations in ASDEX Upgrade' (Nucl. Fusion 44 8277-845). The winner of the 2008 Nuclear Fusion award is Todd Evans et al for the paper `Suppression of large edge localized modes with edge resonant magnetic fields in high confinement DIII-D plasmas' (Nucl. Fusion 45 595-607). The awards were presented by the IAEA Deputy Director General, Werner Burkart, and the Chairman of the Board of Editors, Mitsuru Kikuchi, on 16 October 2008 at the 22nd IAEA Fusion Energy Conference in Geneva, Switzerland. Given the topicality of these papers for the ITER design, it is a matter of pride to the journal that the work should be published in Nuclear Fusion. Reviews Like many who have worked for a long time in the field, I still make use of Nuclear Fusion Reviews that go back 20 or 30 years. It is particularly useful, therefore, that the Board of Editors has been working to re-activate the review programme. The first fruits will appear in this issue, in the form of `A review of zonal flow experiments', by Akihide Fujisawa. The special procedures for Reviews should be noted: most specifically that they should normally be commissioned by the Board of Editors. However, not only is the Board of Editors working on a programme but I am sure that they would be pleased to consider suggestions for review subjects. Letters The reputation of Nuclear

Manuals for Editors and Authors: A Decision Model.

ERIC Educational Resources Information Center

Kirschner, Paul A.

A series of eight manuals dealing with the triad text characteristics--learning processes--learning outcomes are being prepared for use by authors and editors as an aid in the design and writing of educational texts. These manuals are based upon a model for the functioning of text characteristics which in turn is part of a decision model for the…

PanDA Pilot Submission using Condor-G: Experience and Improvements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao X.; Hover John; Wlodek Tomasz

2011-01-01

PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA 'AutoPilot' scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison.more » In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.« less

Adolescent Sexual Initiation through the Lens of Letters to the Editor Published in Polish Teenage Magazines

ERIC Educational Resources Information Center

Kopacz, Marek S.; Bajka-Kopacz, Aleksandra

2012-01-01

Almost all teenage magazines invite readers to submit questions concerning relationships, published as letters to the editor, popularly called "advice columns," often containing explicit questions about sexuality. This study aims to examine, firstly, how themes related to sexual initiation are presented in letters to the editor published…

EDITORIAL: Greetings from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Garcia, Ephrahim

2008-02-01

I am Professor Ephrahim Garcia, an Associate Professor at Sibley School of Mechanical and Aerospace Engineering at Cornell University in Ithaca, New York. I have been at Cornell University since 2002, spent four years as a Program Manager at the Defense Advanced Research Project Agency from 1998-2002, and before that seven years at the Department of Mechanical Engineering at Vanderbilt University in Nashville, Tennessee. I have served on the Editorial Advisory Board of Smart Materials and Structures (SMS) for the last six years. It is a humbling thing to be asked to take up the post of Editor-in-Chief in a field with so many talented researchers. I would like to say a heartfelt thanks to the members of the Editorial Board and IOP Publishing for their confidence in me. Most importantly, I would like to thank Professor Vijay Varadan of the University of Arkansas and Professor Richard Claus of Virginia Polytechnic Institute and State University for their efforts in launching the journal 16 years ago. They have been stewards, promoters and, especially Vijay, key to the operation and function of SMS for all these years, and our research community is indebted to them. Professors Varadan and Claus have dedicated their careers to the area of smart materials and structures and we are very grateful for their leadership, mentoring and contribution. SMS is a thriving journal offering papers on all technical areas concerned with smart materials, systems and structures from the micro- and nanoscale to the macroscale. The journal is undergoing some major changes, including the recent transferal of papers to IOP Publishing's peer-review management system. With this new system authors can expect fast publication times of around 4 or 5 months from submission, and excellent author service. In this world of ever changing technology, the Editorial Board and I aim to reduce the time to publication for researchers in this exciting area of science and engineering. I am in the process of

Multiple extreme environmental conditions of intermittent soda pans in the Carpathian Basin (Central Europe).

PubMed

Boros, Emil; Katalin, V-Balogh; Vörös, Lajos; Horváth, Zsófia

2017-01-01

Soda lakes and pans represent saline ecosystems with unique chemical composition, occurring on all continents. The purpose of this study was to identify and characterise the main environmental gradients and trophic state that prevail in the soda pans (n=84) of the Carpathian Basin in Central Europe. Underwater light conditions, dissolved organic matter, phosphorus and chlorophyll a were investigated in 84 pans during 2009-2010. Besides, water temperature was measured hourly with an automatic sensor throughout one year in a selected pan. The pans were very shallow (median depth: 15 cm), and their extremely high turbidity (Secchi depth median: 3 cm, min: 0.5 cm) was caused by high concentrations of inorganic suspended solids (median: 0.4 g L -1 , max: 16 g L -1 ), which was the dominant (>50%) contributing factor to the vertical attenuation coefficient in 67 pans (80%). All pans were polyhumic (median DOC: 47 mg L -1 ), and total phosphorus concentration was also extremely high (median: 2 mg L -1 , max: 32 mg L -1 ). The daily water temperature maximum (44 °C) and fluctuation maximum (28 °C) were extremely high during summertime. The combination of environmental boundaries: shallowness, daily water temperature fluctuation, intermittent hydroperiod, high turbidity, polyhumic organic carbon concentration, high alkalinity and hypertrophy represent a unique extreme aquatic ecosystem.

Multiple extreme environmental conditions of intermittent soda pans in the Carpathian Basin (Central Europe)

PubMed Central

Boros, Emil; Katalin, V.-Balogh; Vörös, Lajos; Horváth, Zsófia

2017-01-01

Soda lakes and pans represent saline ecosystems with unique chemical composition, occurring on all continents. The purpose of this study was to identify and characterise the main environmental gradients and trophic state that prevail in the soda pans (n=84) of the Carpathian Basin in Central Europe. Underwater light conditions, dissolved organic matter, phosphorus and chlorophyll a were investigated in 84 pans during 2009–2010. Besides, water temperature was measured hourly with an automatic sensor throughout one year in a selected pan. The pans were very shallow (median depth: 15 cm), and their extremely high turbidity (Secchi depth median: 3 cm, min: 0.5 cm) was caused by high concentrations of inorganic suspended solids (median: 0.4 g L–1, max: 16 g L–1), which was the dominant (>50%) contributing factor to the vertical attenuation coefficient in 67 pans (80%). All pans were polyhumic (median DOC: 47 mg L–1), and total phosphorus concentration was also extremely high (median: 2 mg L–1, max: 32 mg L–1). The daily water temperature maximum (44 °C) and fluctuation maximum (28 °C) were extremely high during summertime. The combination of environmental boundaries: shallowness, daily water temperature fluctuation, intermittent hydroperiod, high turbidity, polyhumic organic carbon concentration, high alkalinity and hypertrophy represent a unique extreme aquatic ecosystem. PMID:28572691

Pan-genome and phylogeny of Bacillus cereus sensu lato.

PubMed

Bazinet, Adam L

2017-08-02

Bacillus cereus sensu lato (s. l.) is an ecologically diverse bacterial group of medical and agricultural significance. In this study, I use publicly available genomes and novel bioinformatic workflows to characterize the B. cereus s. l. pan-genome and perform the largest phylogenetic and population genetic analyses of this group to date in terms of the number of genes and taxa included. With these fundamental data in hand, I identify genes associated with particular phenotypic traits (i.e., "pan-GWAS" analysis), and quantify the degree to which taxa sharing common attributes are phylogenetically clustered. A rapid k-mer based approach (Mash) was used to create reduced representations of selected Bacillus genomes, and a fast distance-based phylogenetic analysis of this data (FastME) was performed to determine which species should be included in B. cereus s. l. The complete genomes of eight B. cereus s. l. species were annotated de novo with Prokka, and these annotations were used by Roary to produce the B. cereus s. l. pan-genome. Scoary was used to associate gene presence and absence patterns with various phenotypes. The orthologous protein sequence clusters produced by Roary were filtered and used to build HaMStR databases of gene models that were used in turn to construct phylogenetic data matrices. Phylogenetic analyses used RAxML, DendroPy, ClonalFrameML, PAUP*, and SplitsTree. Bayesian model-based population genetic analysis assigned taxa to clusters using hierBAPS. The genealogical sorting index was used to quantify the phylogenetic clustering of taxa sharing common attributes. The B. cereus s. l. pan-genome currently consists of ≈60,000 genes, ≈600 of which are "core" (common to at least 99% of taxa sampled). Pan-GWAS analysis revealed genes associated with phenotypes such as isolation source, oxygen requirement, and ability to cause diseases such as anthrax or food poisoning. Extensive phylogenetic analyses using an unprecedented amount of data

Developing Media Module Proposed to Editor in Editorial Division

NASA Astrophysics Data System (ADS)

Kristanto, A.; Mustaji; Mariono, A.; Sulistiowati; Nuryati, D. W.

2018-01-01

In this era of technology in Indonesia, various publishers introduce themselves and participate in advancing the quality of education through the publication of various books as the learning sources. One of the publishers is PT. JP Press. In compiling the learning sources, we found some problems that are left unresolved by the editor. The purpose of this research is to overcome the problems that exist in PT. JP Press by developing media module. This development research uses the ADDIE model. The types of data used in this study are qualitative and quantitative data obtained based on the results of structured interviews with material experts and media experts, as well as the editorial response questionnaire provided for individual try-out and small group try-out. Therefore, it can be concluded that the medium of elementary school supplementary module proposed to the editors of PT. JP Press is valuable to be used in the teaching and learning activities.

Innovative uses of GigaPan Technology for Onsite and Distance Education

NASA Astrophysics Data System (ADS)

Bentley, C.; Schott, R. C.; Piatek, J. L.; Richards, B.

2013-12-01

GigaPans are gigapixel panoramic images that can be viewed at a wide range of magnifications, allowing users to explore them in various degrees of detail from the smallest scale to the full image extent. In addition to panoramic images captured with the GigaPan camera mount ('Dry Falls' - http://www.gigapan.com/gigapans/89093), users can also upload annotated images (For example, 'Massanutten sandstone slab with trace fossils (annotated)', http://www.gigapan.com/gigapans/124295) and satellite images (For example, 'Geology vs. Topography - State of Connecticut', http://www.gigapan.com/gigapans/111265). Panoramas with similar topics have been gathered together on the site in galleries, both user-generated and site-curated (For example, http://www.gigapan.com/galleries?categories=geology&page=1). Further innovations in display technology have also led to the development of improved viewers (for example, the annotations in the image linked above can be explored via paired viewers at http://coursecontent.nic.edu/bdrichards/gigapixelimages/callanview) GigaPan panoramas can be created through use of the GigaPan robotic camera mount and a digital camera (different models of the camera mount are available and work with a wide range of cameras). The camera mount can be used to create high-resolution pans ranging in scale from hand sample to outcrop up to landscape via the stitching software included with the robotic mount. The software can also be used to generate GigaPan images from other sources, such as thin section or satellite images, so these images can also be viewed with the online viewer. GigaPan images are typically viewed via a web-based interface that allows the user to interact with the image from the limits of the image detail up to the full panorama. After uploading, information can be added to panoramas with both text captions and geo-referencing (geo-located panoramas can then be viewed in Google Earth). Users can record specific locations and zoom levels in

Multivalent small molecule pan-RAS inhibitors

PubMed Central

Welsch, Matthew E.; Kaplan, Anna; Chambers, Jennifer M.; Stokes, Michael E.; Bos, Pieter H.; Zask, Arie; Zhang, Yan; Sanchez-Martin, Marta; Badgley, Michael A.; Huang, Christine S.; Tran, Timothy H.; Akkiraju, Hemanth; Brown, Lewis M.; Nandakumar, Renu; Cremers, Serge; Yang, Wan S.; Tong, Liang; Olive, Kenneth P.; Ferrando, Adolfo; Stockwell, Brent R.

2017-01-01

SUMMARY Design of small molecules that disrupt protein-protein interactions, including the interaction of RAS proteins and their effectors, have potential use as chemical probes and therapeutic agents. We describe here the synthesis and testing of potential small molecule pan-RAS ligands, which were designed to interact with adjacent sites on the surface of oncogenic KRAS. One compound, termed 3144, was found to bind to RAS proteins using microscale thermophoresis, nuclear magnetic resonance spectroscopy and isothermal titration calorimetry, and to exhibit lethality in cells partially dependent on expression of RAS proteins. This compound was metabolically stable in liver microsomes and displayed anti-tumor activity in xenograft mouse cancer models. These findings suggest that pan-RAS inhibition may be an effective therapeutic strategy for some cancers, and that structure-based design of small molecules targeting multiple adjacent sites to create multivalent inhibitors may be effective for some proteins. PMID:28235199

Technical research aspect of the Pan-Pacific Information Network using satellite

NASA Astrophysics Data System (ADS)

Iida, Takashi; Morikawa, Hisashi; Noguchi, Shoichi

The Pan-Pacific Information Network would provide an important new mechanism for education, research, health service, emergency communication, and cultural exchange. The paper discusses the technical research items related to the Pan-Pacific Information Network, reviews small earth-station systems, and considers the system configuration pointed to the network in the Asia/Pacific region.

Targeting the HER family with Pan-HER effectively overcomes resistance to cetuximab

PubMed Central

Iida, Mari; Bahrar, Harsh; Brand, Toni M; Pearson, Hannah E; Coan, John P; Orbuch, Rachel A; Flanigan, Bailey G; Swick, Adam D; Prabakaran, Prashanth; Lantto, Johan; Horak, Ivan D.; Kragh, Michael; Salgia, Ravi; Kimple, Randy J; Wheeler, Deric L

2016-01-01

Cetuximab, an antibody against the Epidermal Growth Factor Receptor (EGFR) has shown efficacy in treating head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer and non-small cell lung cancer (NSCLC). Despite the clinical success of cetuximab, many patients do not respond to cetuximab. Furthermore, virtually all patients who do initially respond become refractory, highlighting both intrinsic and acquired resistance to cetuximab as significant clinical problems. To understand mechanistically how cancerous cells acquire resistance, we previously developed models of acquired resistance using the H226 NSCLC and UM-SCC1 HNSCC cell lines. Cetuximab-resistant clones showed a robust upregulation and dependency on the HER family receptors EGFR, HER2 and HER3. Here, we examined Pan-HER, a mixture of six antibodies targeting these receptors on cetuximab-resistant clones. In cells exhibiting acquired or intrinsic resistance to cetuximab, Pan-HER treatment decreased all three receptors’ protein levels and down-stream activation of AKT and MAPK. This correlated with decreased cell proliferation in cetuximab-resistant clones. To determine whether Pan-HER had a therapeutic benefit in vivo, we established de novo cetuximab-resistant mouse xenografts and treated resistant tumors with Pan-HER. This regimen resulted in a superior growth delay of cetuximab-resistant xenografts compared to mice continued on cetuximab. Furthermore, intrinsically cetuximab-resistant HNSCC patient-derived xenograft tumors treated with Pan-HER exhibited significant growth delay compared to vehicle/cetuximab controls. These results suggest that targeting HER family receptors simultaneously with Pan-HER is a promising treatment strategy for tumors displaying intrinsic or acquired resistance to cetuximab. PMID:27422810

Comparing infant and juvenile behavior in bonobos (Pan paniscus) and chimpanzees (Pan troglodytes): a preliminary study.

PubMed

De Lathouwers, Mieke; Van Elsacker, Linda

2006-10-01

The dichotomy between the two Pan species, the bonobo (Pan paniscus) and chimpanzee (Pan troglodytes) has been strongly emphasized until very recently. Given that most studies were primarily based on adult individuals, we shifted the "continuity versus discontinuity" discussion to the infant and juvenile stage. Our aim was to test quantitatively, some conflicting statements made in literature considering species differences between immature bonobos and chimpanzees. On one hand it is suggested that infant bonobos show retardation in motor and social development when compared with chimpanzees. Additionally it is expected that the weaning process is more traumatic to chimpanzee than bonobo infants. But on the other hand the development of behaviors is expected to be very similar in both species. We observed eight mother-infant pairs of each species in several European zoos. Our preliminary research partially confirms that immature chimpanzees seem spatially more independent, spending more time at a larger distance from their mother than immature bonobos. However, the other data do not seem to support the hypothesis that bonobo infants show retardation of motor or social development. The development of solitary play, environmental exploration, social play, non-copulatory mounts and aggressive interactions do not differ between the species. Bonobo infants in general even groom other group members more than chimpanzee infants. We also found that older bonobo infants have more nipple contact than same aged chimpanzees and that the weaning process seems to end later for bonobos than for immature chimpanzee. Additionally, although immature bonobos show in general more signs of distress, our data suggest that the weaning period itself is more traumatic for chimpanzees.

Characteristics of PAN (Peroxyacetyl Nitrate) in Outflow Plumes Over the Yellow Sea During KORUS-AQ Campaign

NASA Astrophysics Data System (ADS)

Seo, J.; Inae, K.; Lee, M.; Shin, B.; Ryoo, S.; Jung, J.; Kim, S. W.

2017-12-01

Peroxyacetyl nitrate (PAN) is a secondary atmospheric pollutant which is generated by photochemical reaction of VOCs (Volatile Organic Compounds) and NOx (NO+NO2). While PAN has been known as an indicator of photochemical smog in urban areas, it serves as a robust tracer for long-range transport in remote regions. Research vessel Gisang 1 explored the Yellow Sea during May and June 2016, measuring reactive gases including PAN, O3, and NOx. The research area covers the region between 31° 38°N and 124° 127°E. PAN was measured using GC-LCD (Gas Chromatography Luminol Chemiluminescence Detection) every 2 minutes. The average mixing ratio of PAN was the highest (1.1 ppbv) in the second shift (May 17-30) and lower in the first (0.92 ppbv) and third (0.48 ppbv) shift. The PAN concentrations higher than the 95th percentile (2.19 ppbv) were observed on May 21 and 22 in air mass passing through Seoul Metropolitan Areas. In contrast, on May 4 and 29, both PAN and O3 were high under influence of Chinese outflows. On May 6 when dust storm passed through the Yellow Sea, both PAN and O3 concentrations were at their minimum levels. It is noteworthy that PAN concentration was higher with low O3 level near the west coast of Korean peninsula, which was likely to be the influence of ship emissions.

PanFP: pangenome-based functional profiles for microbial communities.

PubMed

Jun, Se-Ran; Robeson, Michael S; Hauser, Loren J; Schadt, Christopher W; Gorin, Andrey A

2015-09-26

For decades there has been increasing interest in understanding the relationships between microbial communities and ecosystem functions. Current DNA sequencing technologies allows for the exploration of microbial communities in two principle ways: targeted rRNA gene surveys and shotgun metagenomics. For large study designs, it is often still prohibitively expensive to sequence metagenomes at both the breadth and depth necessary to statistically capture the true functional diversity of a community. Although rRNA gene surveys provide no direct evidence of function, they do provide a reasonable estimation of microbial diversity, while being a very cost-effective way to screen samples of interest for later shotgun metagenomic analyses. However, there is a great deal of 16S rRNA gene survey data currently available from diverse environments, and thus a need for tools to infer functional composition of environmental samples based on 16S rRNA gene survey data. We present a computational method called pangenome-based functional profiles (PanFP), which infers functional profiles of microbial communities from 16S rRNA gene survey data for Bacteria and Archaea. PanFP is based on pangenome reconstruction of a 16S rRNA gene operational taxonomic unit (OTU) from known genes and genomes pooled from the OTU's taxonomic lineage. From this lineage, we derive an OTU functional profile by weighting a pangenome's functional profile with the OTUs abundance observed in a given sample. We validated our method by comparing PanFP to the functional profiles obtained from the direct shotgun metagenomic measurement of 65 diverse communities via Spearman correlation coefficients. These correlations improved with increasing sequencing depth, within the range of 0.8-0.9 for the most deeply sequenced Human Microbiome Project mock community samples. PanFP is very similar in performance to another recently released tool, PICRUSt, for almost all of survey data analysed here. But, our method is unique

Isotopic composition of atmospheric moisture from pan water evaporation measurements.

PubMed

Devi, Pooja; Jain, Ashok Kumar; Rao, M Someshwer; Kumar, Bhishm

2015-01-01

A continuous and reliable time series data of the stable isotopic composition of atmospheric moisture is an important requirement for the wider applicability of isotope mass balance methods in atmospheric and water balance studies. This requires routine sampling of atmospheric moisture by an appropriate technique and analysis of moisture for its isotopic composition. We have, therefore, used a much simpler method based on an isotope mass balance approach to derive the isotopic composition of atmospheric moisture using a class-A drying evaporation pan. We have carried out the study by collecting water samples from a class-A drying evaporation pan and also by collecting atmospheric moisture using the cryogenic trap method at the National Institute of Hydrology, Roorkee, India, during a pre-monsoon period. We compared the isotopic composition of atmospheric moisture obtained by using the class-A drying evaporation pan method with the cryogenic trap method. The results obtained from the evaporation pan water compare well with the cryogenic based method. Thus, the study establishes a cost-effective means of maintaining time series data of the isotopic composition of atmospheric moisture at meteorological observatories. The conclusions drawn in the present study are based on experiments conducted at Roorkee, India, and may be examined at other regions for its general applicability.

[The relevance of the International Committee of Medical Journal Editors (ICMJE) for medical publishing and research].

PubMed

Reyes, Humberto B

2014-01-01

The International Committee of Medical Journal Editors is a leading independent institution providing guidance for the report of biomedical research and health related topics in medical journals. Established in 1978, it is currently constituted by editors of fourteen general medical journals from different countries, plus one representative for the US National Library of Medicine and one representative for the World Association of Biomedical Journal Editors. Since 1978 the Committee provides a document, originally named "Uniform Requirements…", "to help authors, editors, and others involved in peer review and biomedical publishing create and distribute accurate, clear, unbiased medical journal articles". This document has been updated several times and the last version was released in August 2013, now renamed "Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals", available in www.icmje.org and citable as "ICMJE Recommendations". A vast proportion of medical journals, worldwide, have adopted these recommendations as rules. The ICMJE discusses and provides guidance on several relevant aspects including criteria on authorship, peer review, scientific misconduct, conflicts of interest, clinical trials registration, good editorial practices, the relations between editors and journal owners, the protection of individuals subject to medical research, the solvency of electronic publications, among others. The 2013 ICMJE Annual Meeting took place in Santiago, Chile, in November 4 and 5. The photograph shows attendants to the final session.

EUPAN enables pan-genome studies of a large number of eukaryotic genomes.

PubMed

Hu, Zhiqiang; Sun, Chen; Lu, Kuang-Chen; Chu, Xixia; Zhao, Yue; Lu, Jinyuan; Shi, Jianxin; Wei, Chaochun

2017-08-01

Pan-genome analyses are routinely carried out for bacteria to interpret the within-species gene presence/absence variations (PAVs). However, pan-genome analyses are rare for eukaryotes due to the large sizes and higher complexities of their genomes. Here we proposed EUPAN, a eukaryotic pan-genome analysis toolkit, enabling automatic large-scale eukaryotic pan-genome analyses and detection of gene PAVs at a relatively low sequencing depth. In the previous studies, we demonstrated the effectiveness and high accuracy of EUPAN in the pan-genome analysis of 453 rice genomes, in which we also revealed widespread gene PAVs among individual rice genomes. Moreover, EUPAN can be directly applied to the current re-sequencing projects primarily focusing on single nucleotide polymorphisms. EUPAN is implemented in Perl, R and C ++. It is supported under Linux and preferred for a computer cluster with LSF and SLURM job scheduling system. EUPAN together with its standard operating procedure (SOP) is freely available for non-commercial use (CC BY-NC 4.0) at http://cgm.sjtu.edu.cn/eupan/index.html . ccwei@sjtu.edu.cn or jianxin.shi@sjtu.edu.cn. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

High levels of Y-chromosome nucleotide diversity in the genus Pan

PubMed Central

Stone, Anne C.; Griffiths, Robert C.; Zegura, Stephen L.; Hammer, Michael F.

2002-01-01

Although some mitochondrial, X chromosome, and autosomal sequence diversity data are available for our closest relatives, Pan troglodytes and Pan paniscus, data from the nonrecombining portion of the Y chromosome (NRY) are more limited. We examined ≈3 kb of NRY DNA from 101 chimpanzees, seven bonobos, and 42 humans to investigate: (i) relative levels of intraspecific diversity; (ii) the degree of paternal lineage sorting among species and subspecies of the genus Pan; and (iii) the date of the chimpanzee/bonobo divergence. We identified 10 informative sequence-tagged sites associated with 23 polymorphisms on the NRY from the genus Pan. Nucleotide diversity was significantly higher on the NRY of chimpanzees and bonobos than on the human NRY. Similar to mtDNA, but unlike X-linked and autosomal loci, lineages defined by mutations on the NRY were not shared among subspecies of P. troglodytes. Comparisons with mtDNA ND2 sequences from some of the same individuals revealed a larger female versus male effective population size for chimpanzees. The NRY-based divergence time between chimpanzees and bonobos was estimated at ≈1.8 million years ago. In contrast to human populations who appear to have had a low effective size and a recent origin with subsequent population growth, some taxa within the genus Pan may be characterized by large populations of relatively constant size, more ancient origins, and high levels of subdivision. PMID:11756656

Form gene clustering method about pan-ethnic-group products based on emotional semantic

NASA Astrophysics Data System (ADS)

Chen, Dengkai; Ding, Jingjing; Gao, Minzhuo; Ma, Danping; Liu, Donghui

2016-09-01

The use of pan-ethnic-group products form knowledge primarily depends on a designer's subjective experience without user participation. The majority of studies primarily focus on the detection of the perceptual demands of consumers from the target product category. A pan-ethnic-group products form gene clustering method based on emotional semantic is constructed. Consumers' perceptual images of the pan-ethnic-group products are obtained by means of product form gene extraction and coding and computer aided product form clustering technology. A case of form gene clustering about the typical pan-ethnic-group products is investigated which indicates that the method is feasible. This paper opens up a new direction for the future development of product form design which improves the agility of product design process in the era of Industry 4.0.

Magazine or journal--what is the difference? The role of the monitoring editor.

PubMed

Bretscher, Anthony

2013-04-01

Scientific communication, career advancement, and funding decisions are all dependent on research publications. The way manuscripts are handled by high-visibility, professionally edited magazines differs from the way academic journals evaluate manuscripts, using active scientists as monitoring editors. In this essay, I discuss the benefits that come with the involvement of active scientists. I enumerate the decisions a monitoring editor has to make, and how he or she goes about making them. Finally, I indicate ways in which authors can help to make the process a smoother and more positive experience.

A method for installing zero-tension pan and wick lysimeters in soil

USDA-ARS?s Scientific Manuscript database

Zero-tension pan lysimeters and passive capillary fiberglass wick lysimeters are useful in determining water quality and volumetric aspects of subsurface water flow. Installation of pan and wick lysimeters beneath undisturbed soil may be complicated by the tendency for the soil to cave-in as the lys...

Can editors save peer review from peer reviewers?

PubMed

D'Andrea, Rafael; O'Dwyer, James P

2017-01-01

Peer review is the gold standard for scientific communication, but its ability to guarantee the quality of published research remains difficult to verify. Recent modeling studies suggest that peer review is sensitive to reviewer misbehavior, and it has been claimed that referees who sabotage work they perceive as competition may severely undermine the quality of publications. Here we examine which aspects of suboptimal reviewing practices most strongly impact quality, and test different mitigating strategies that editors may employ to counter them. We find that the biggest hazard to the quality of published literature is not selfish rejection of high-quality manuscripts but indifferent acceptance of low-quality ones. Bypassing or blacklisting bad reviewers and consulting additional reviewers to settle disagreements can reduce but not eliminate the impact. The other editorial strategies we tested do not significantly improve quality, but pairing manuscripts to reviewers unlikely to selfishly reject them and allowing revision of rejected manuscripts minimize rejection of above-average manuscripts. In its current form, peer review offers few incentives for impartial reviewing efforts. Editors can help, but structural changes are more likely to have a stronger impact.

Rotatable prism for pan and tilt

NASA Technical Reports Server (NTRS)

Ball, W. B.

1980-01-01

Compact, inexpensive, motor-driven prisms change field of view of TV camera. Camera and prism rotate about lens axis to produce pan effect. Rotating prism around axis parallel to lens produces tilt. Size of drive unit and required clearance are little more than size of camera.

PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats

PubMed Central

Winocur, Gordon; Wojtowicz, J. Martin; Shevtsova, Olga; Fuller, Steven; Ghanbari, Hossein A.

2018-01-01

Chemotherapy-induced cognitive impairment (CICI) occurs in a substantial proportion of treated cancer patients, with no drug currently available for its therapy. This study investigated whether PAN-811, a ribonucleotide reductase inhibitor, can reduce cognitive impairment and related suppression of neurogenesis following chemotherapy in an animal model. Young adult rats in Chemo and Chemo+PAN-811 groups received 3 intraperitoneal (i.p.) injections of methotrexate (MTX) and 5-fluorouracil (5-FU), and those in Saline and Saline+PAN-811 groups received equal volumes of physiological saline at 10-day intervals. PAN-811 in saline was delivered through i.p. injection, 10 min following each saline (Saline+PAN-811 group) or MTX/5-FU (Chemo+PAN-811 group) treatment, while equal volumes of saline were delivered to Saline and Chemo groups. Over Days 31–66, rats were administered tests of spatial memory, nonmatching-to-sample rule learning, and discrimination learning, which are sensitive to dysfunction in hippocampus, frontal lobe and striatum, respectively. On Day 97, neurogenesis was immnunohistochemically evaluated by counting doublecortin-positive (DCX+) cells in the dentate gyrus (DG). The results demonstrated that the Chemo group was impaired on the three cognitive tasks, but co-administration of PAN-811 significantly reduced all MTX/5-FU-induced cognitive impairments. In addition, MTX/5-FU reduced DCX+ cells to 67% of that in Saline control rats, an effect that was completely blocked by PAN-811 co-administration. Overall, we present the first evidence that PAN-811 protects cognitive functions and preserves neurogenesis from deleterious effects of MTX/5-FU. The current findings provide a basis for rapid clinical translation to determine the effect of PAN-811 on CICI in human. PMID:29370277

Structure, thermal and luminescence properties of Eu/Tb(BA)3phen/PAN fibers fabricated by electrospinning

NASA Astrophysics Data System (ADS)

Wang, Shiwei; Xie, Guangbo; Zhang, Jingjing; Zhang, Sen; Li, Tingju

2018-04-01

Novel high luminescence fibers often exhibit potential applications in the fields of color displays and sensor systems. In this study, Eu(BA)3phen and Tb(BA)3phen powders was successfully synthesized by solvothermal reactions, firstly. Then, three kinds of novel flexible Eu(BA)3phen/PAN, Tb(BA)3phen/PAN and Eu/Tb(BA)3phen/PAN (BA = benzoic acid, phen = phenanthroline, PAN = Polyacrylonitrile) fibers had been successfully prepared by electrospinning technology. The characterizations of the final products have been investigated in detail. It was found that the diameter of the as-prepared fibers were almost uniform with the fabricated complexes doping into PAN successfully. Thermogravimetric analysis indicates that the thermal stability of the pure PAN fiber could be improved by the incorporation of the complex, although only 1 wt % was added. Furthermore, in Eu/Tb(BA)3phen complex, the fluorescence intensity of Eu3+ ions was remarkably increased by adding Tb3+ ions. This is primarily due to an energy transfer from the 5D4 level of Tb (III) to the 5D0 level of Eu (III) ions, where Tb3+ acted as sensitizer. The corresponding luminescent fibers displayed the same regularity as the complexes. Moreover, with the increasing of the incorporation of complexes into PAN, the fluorescence intensities were significantly enhanced and reached its maximum value at 2.5 wt % for Eu(BA)3phen/PAN fibers and 2.0 wt% for Tb(BA)3phen/PAN fibers. The further intensity decreased with the increasing content of the complexes because of typical emission concentration quenching.

Trends in pan evaporation and actual evapotranspiration across the conterminous U.S.: paradoxical or complementary?

Treesearch

Michael T. Hobbins; Jorge A. Ramirez; Thomas C. Brown

2004-01-01

Pan evaporation (ETpan) has decreased at 64% of pans in the conterminous U.S. over the past half-century. Comparing trends in ETpan and water budget-derived actual evapotranspiration (ET*a), we observe the so-called ‘‘Pan Evaporation Paradox,’’ which we confirm is no more than a...

FlaME: Flash Molecular Editor - a 2D structure input tool for the web.

PubMed

Dallakian, Pavel; Haider, Norbert

2011-02-01

So far, there have been no Flash-based web tools available for chemical structure input. The authors herein present a feasibility study, aiming at the development of a compact and easy-to-use 2D structure editor, using Adobe's Flash technology and its programming language, ActionScript. As a reference model application from the Java world, we selected the Java Molecular Editor (JME). In this feasibility study, we made an attempt to realize a subset of JME's functionality in the Flash Molecular Editor (FlaME) utility. These basic capabilities are: structure input, editing and depiction of single molecules, data import and export in molfile format. The result of molecular diagram sketching in FlaME is accessible in V2000 molfile format. By integrating the molecular editor into a web page, its communication with the HTML elements on this page is established using the two JavaScript functions, getMol() and setMol(). In addition, structures can be copied to the system clipboard. A first attempt was made to create a compact single-file application for 2D molecular structure input/editing on the web, based on Flash technology. With the application examples presented in this article, it could be demonstrated that the Flash methods are principally well-suited to provide the requisite communication between the Flash object (application) and the HTML elements on a web page, using JavaScript functions.

Development of pan-Arctic database for river chemistry

USGS Publications Warehouse

McClelland, J.W.; Holmes, R.M.; Peterson, B.J.; Amon, R.; Brabets, T.; Cooper, L.; Gibson, J.; Gordeev, V.V.; Guay, C.; Milburn, D.; Staples, R.; Raymond, P.A.; Shiklomanov, I.; Striegl, Robert G.; Zhulidov, A.; Gurtovaya, T.; Zimov, S.

2008-01-01

More than 10% of all continental runoff flows into the Arctic Ocean. This runoff is a dominant feature of the Arctic Ocean with respect to water column structure and circulation. Yet understanding of the chemical characteristics of runoff from the pan-Arctic watershed is surprisingly limited. The Pan- Arctic River Transport of Nutrients, Organic Matter, and Suspended Sediments ( PARTNERS) project was initiated in 2002 to help remedy this deficit, and an extraordinary data set has emerged over the past few years as a result of the effort. This data set is publicly available through the Cooperative Arctic Data and Information Service (CADIS) of the Arctic Observing Network (AON). Details about data access are provided below.

Volumetric and Lateralized Differences in Selected Brain Regions of Chimpanzees (Pan troglodytes) and Bonobos (Pan paniscus)

PubMed Central

Hopkins, William D.; Lyn, Heidi; Cantalupo, Claudio

2009-01-01

The two species of Pan, bonobos and common chimpanzees, have been reported to have different social organization, cognitive and linguistic abilities and motor skill, despite their close biological relationship. Here, we examined whether bonobos and chimpanzee differ in selected brain regions that may map to these different social and cognitive abilities. Eight chimpanzees and eight bonobos matched on age, sex and rearing experiences were magnetic resonance images scanned and volumetric measures were obtained for the whole brain, cerebellum, striatum, motor-hand area, hippocampus, inferior frontal gyrus and planum temporale. Chimpanzees had significantly larger cerebellum and borderline significantly larger hippocampus and putamen, after adjusting for brain size, compared with bonobos. Bonobos showed greater leftward asymmetries in the striatum and motor-hand area compared with chimpanzees. No significant differences in either the volume or lateralization for the so-called language homologs were found between species. The results suggest that the two species of Pan are quite similar neurologically, though some volumetric and lateralized differences may reflect inherent differences in social organization, cognition and motor skills. PMID:19760676

Volumetric and lateralized differences in selected brain regions of chimpanzees (Pan troglodytes) and bonobos (Pan paniscus).

PubMed

Hopkins, William D; Lyn, Heidi; Cantalupo, Claudio

2009-12-01

The two species of Pan, bonobos and common chimpanzees, have been reported to have different social organization, cognitive and linguistic abilities and motor skill, despite their close biological relationship. Here, we examined whether bonobos and chimpanzee differ in selected brain regions that may map to these different social and cognitive abilities. Eight chimpanzees and eight bonobos matched on age, sex and rearing experiences were magnetic resonance images scanned and volumetric measures were obtained for the whole brain, cerebellum, striatum, motor-hand area, hippocampus, inferior frontal gyrus and planum temporale. Chimpanzees had significantly larger cerebellum and borderline significantly larger hippocampus and putamen, after adjusting for brain size, compared with bonobos. Bonobos showed greater leftward asymmetries in the striatum and motor-hand area compared with chimpanzees. No significant differences in either the volume or lateralization for the so-called language homologs were found between species. The results suggest that the two species of Pan are quite similar neurologically, though some volumetric and lateralized differences may reflect inherent differences in social organization, cognition and motor skills.

3 CFR 8495 - Proclamation 8495 of April 9, 2010. Pan American Day and Pan American Week, 2010

Code of Federal Regulations, 2011 CFR

2011-01-01

... United States of America A Proclamation More than 200 years of history and significant current events... Americas. The year 2010 marks the 80th anniversary of the first Pan American Day Proclamation; the..., and Chile. These milestones remind us of our shared histories of independence and interdependence, and...

How Innovative Are Editors?: Evidence across Journals and Disciplines

ERIC Educational Resources Information Center

Petersen, Jessica

2017-01-01

Journal editors play a crucial role in the scientific publication system, as they make the final decision on acceptance or rejection of manuscripts. Some critics, however, suspect that the more innovative a manuscript is, the less likely it will be accepted for publication. Especially top-tier journals are accused of rejecting innovative research.…

CMS Configuration Editor: GUI based application for user analysis job

NASA Astrophysics Data System (ADS)

de Cosa, A.

2011-12-01

We present the user interface and the software architecture of the Configuration Editor for the CMS experiment. The analysis workflow is organized in a modular way integrated within the CMS framework that organizes in a flexible way user analysis code. The Python scripting language is adopted to define the job configuration that drives the analysis workflow. It could be a challenging task for users, especially for newcomers, to develop analysis jobs managing the configuration of many required modules. For this reason a graphical tool has been conceived in order to edit and inspect configuration files. A set of common analysis tools defined in the CMS Physics Analysis Toolkit (PAT) can be steered and configured using the Config Editor. A user-defined analysis workflow can be produced starting from a standard configuration file, applying and configuring PAT tools according to the specific user requirements. CMS users can adopt this tool, the Config Editor, to create their analysis visualizing in real time which are the effects of their actions. They can visualize the structure of their configuration, look at the modules included in the workflow, inspect the dependences existing among the modules and check the data flow. They can visualize at which values parameters are set and change them according to what is required by their analysis task. The integration of common tools in the GUI needed to adopt an object-oriented structure in the Python definition of the PAT tools and the definition of a layer of abstraction from which all PAT tools inherit.

Dynamic analysis of pan evaporation variations in the Huai River Basin, a climate transition zone in eastern China.

PubMed

Li, Meng; Chu, Ronghao; Shen, Shuanghe; Islam, Abu Reza Md Towfiqul

2018-06-01

Pan evaporation (E pan ), which we examine in this study to better understand atmospheric evaporation demand, represents a pivotal indicator of the terrestrial ecosystem and hydrological cycle, particularly in the Huai River Basin (HRB) in eastern China, where high potential risks of drought and flooding are commonly observed. In this study, we examine the spatiotemporal trend patterns of climatic factors and E pan by using the Mann-Kendall test and the Theil-Sen estimator based on a daily meteorological dataset from 89 weather stations during 1965-2013 in the HRB. Furthermore, the PenPan model is employed to estimate E pan at a monthly time scale, and a differential equation method is applied to quantify contributions from four meteorological variables to E pan trends. The results show that E pan significantly decreased (P<0.001) at an average rate of -8.119mm·a -2 at annual time scale in the whole HRB, with approximately 90% of stations occupied. Meanwhile, the generally higher E pan values were detected in the northern HRB. The values of the aerodynamic components in the PenPan model were much greater than those of the radiative components, which were responsible for the variations in the E pan trend. The significantly decreasing wind speed (u 2 ) was the most dominant factor that controlled the decreasing E pan trend at each time scale, followed by the notable decreasing net radiation (R n ) at the annual time scale also in growing season and summer. However, the second dominant factor shifted to the mean temperature (T a ) during the spring and winter and the vapor pressure deficit (vpd) during the autumn. These phenomena demonstrated a positive link between the significance of climate variables and their control over the E pan trend. Copyright © 2017 Elsevier B.V. All rights reserved.

Imitation in Neonatal Chimpanzees ("Pan Troglodytes")

ERIC Educational Resources Information Center

Myowa-Yamakoshi, Masako; Tomonaga, Masaki; Tanaka, Masayuki; Matsuzawa, Tetsuro

2004-01-01

This paper provides evidence for imitative abilities in neonatal chimpanzees ("Pan troglodytes"), our closest relatives. Two chimpanzees were reared from birth by their biological mothers. At less than 7 days of age the chimpanzees could discriminate between, and imitate, human facial gestures (tongue protrusion and mouth opening). By the time…

ATLAS WORLD-cloud and networking in PanDA

NASA Astrophysics Data System (ADS)

Barreiro Megino, F.; De, K.; Di Girolamo, A.; Maeno, T.; Walker, R.; ATLAS Collaboration

2017-10-01

The ATLAS computing model was originally designed as static clouds (usually national or geographical groupings of sites) around the Tier 1 centres, which confined tasks and most of the data traffic. Since those early days, the sites’ network bandwidth has increased at 0(1000) and the difference in functionalities between Tier 1s and Tier 2s has reduced. After years of manual, intermediate solutions, we have now ramped up to full usage of World-cloud, the latest step in the PanDA Workload Management System to increase resource utilization on the ATLAS Grid, for all workflows (MC production, data (re)processing, etc.). We have based the development on two new site concepts. Nuclei sites are the Tier 1s and large Tier 2s, where tasks will be assigned and the output aggregated, and satellites are the sites that will execute the jobs and send the output to their nucleus. PanDA dynamically pairs nuclei and satellite sites for each task based on the input data availability, capability matching, site load and network connectivity. This contribution will introduce the conceptual changes for World-cloud, the development necessary in PanDA, an insight into the network model and the first half-year of operational experience.

PAN AIR modeling studies. [higher order panel method for aircraft design

NASA Technical Reports Server (NTRS)

Towne, M. C.; Strande, S. M.; Erickson, L. L.; Kroo, I. M.; Enomoto, F. Y.; Carmichael, R. L.; Mcpherson, K. F.

1983-01-01

PAN AIR is a computer program that predicts subsonic or supersonic linear potential flow about arbitrary configurations. The code's versatility and generality afford numerous possibilities for modeling flow problems. Although this generality provides great flexibility, it also means that studies are required to establish the dos and don'ts of modeling. The purpose of this paper is to describe and evaluate a variety of methods for modeling flows with PAN AIR. The areas discussed are effects of panel density, internal flow modeling, forebody modeling in subsonic flow, propeller slipstream modeling, effect of wake length, wing-tail-wake interaction, effect of trailing-edge paneling on the Kutta condition, well- and ill-posed boundary-value problems, and induced-drag calculations. These nine topics address problems that are of practical interest to the users of PAN AIR.

A Portable Burn Pan for the Disposal of Excess Propellants

DTIC Science & Technology

2015-11-01

project objective for the total mass of the HTU burn pan of less than 120 kg. The bonnet was made more durable while eliminating hazardous sharp edges...remaining in the pan will need to be considered hazardous . The sponsoring facility representatives, Mr. Steve Thurmond and Ms. Ellen Clark, agreed to...Don’t need the door on the bonnet any more – remove from next iteration − Beef up the mounting of the legs on the base After-action Tasks (CRREL

Pan American World Airways flight training: A new direction. Flight operations resource management

NASA Technical Reports Server (NTRS)

Butler, Roy

1987-01-01

The Pan Am Flight Training Department shares the experiences it is having in its attempt to integrate cockpit resource management philosophies into its training programs. A slide-tape presentation on Pan Am's new direction in flight training is presented and briefly discussed.

Share your sweets: Chimpanzee (Pan troglodytes) and bonobo (Pan paniscus) willingness to share highly attractive, monopolizable food sources.

PubMed

Byrnit, Jill T; Høgh-Olesen, Henrik; Makransky, Guido

2015-08-01

All over the world, humans (Homo sapiens) display resource-sharing behavior, and common patterns of sharing seem to exist across cultures. Humans are not the only primates to share, and observations from the wild have long documented food sharing behavior in our closest phylogenetic relatives, chimpanzees (Pan troglodytes) and bonobos (Pan paniscus). However, few controlled studies have been made in which groups of Pan are introduced to food items that may be shared or monopolized by a first food possessor, and very few studies have examined what happens to these sharing patterns if the food in question is a highly attractive, monopolizable food source. The one study to date to include food quality as the independent variable used different types of food as high- and low-value items, making differences in food divisibility and size potentially confounding factors. It was the aim of the present study to examine the sharing behavior of groups of captive chimpanzees and bonobos when introducing the same type of food (branches) manipulated to be of 2 different degrees of desirability (with or without syrup). Results showed that the large majority of food transfers in both species came about as sharing in which group members were allowed to cofeed or remove food from the stock of the food possessor, and the introduction of high-value food resulted in more sharing, not less. Food sharing behavior differed between species in that chimpanzees displayed significantly more begging behavior than bonobos. Bonobos, instead, engaged in sexual invitations, which the chimpanzees never did. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Integration of PanDA workload management system with Titan supercomputer at OLCF

NASA Astrophysics Data System (ADS)

De, K.; Klimentov, A.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.

2015-12-01

The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently distributes jobs to more than 100,000 cores at well over 100 Grid sites, the future LHC data taking runs will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). The current approach utilizes a modified PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multicore worker nodes. It also gives PanDA new capability to collect, in real time, information about unused worker nodes on Titan, which allows precise definition of the size and duration of jobs submitted to Titan according to available free resources. This capability significantly reduces PanDA job wait time while improving Titan's utilization efficiency. This implementation was tested with a variety of Monte-Carlo workloads on Titan and is being tested on several other supercomputing platforms. Notice: This manuscript has been authored, by employees of Brookhaven Science Associates, LLC under Contract No. DE-AC02-98CH10886 with the U.S. Department of Energy. The publisher by accepting the manuscript for publication acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes.

Bioenergy and biodiversity: Key lessons from the Pan American region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kline, Keith L.; Martinelli, Fernanda Silva; Mayer, Audrey L.

Understanding how large-scale bioenergy production can affect biodiversity and ecosystems is important if society is to meet current and future sustainable development goals. A variety of bioenergy production systems have been established within different contexts throughout the Pan American region, with wide-ranging results in terms of documented and projected effects on biodiversity and ecosystems. The Pan American region is home to the majority of commercial bioenergy production and therefore the region offers a broad set of experiences and insights on both conflicts and opportunities for biodiversity and bioenergy. This paper synthesizes lessons learned focusing on experiences in Canada, the Unitedmore » States, and Brazil, regarding the conflicts that can arise between bioenergy production and ecological conservation, and benefits that can be derived when bioenergy policies promote planning and more sustainable land management systems. Lastly, we propose a research agenda to address priority information gaps that are relevant to biodiversity concerns and related policy challenges in the Pan American region.« less

Bioenergy and Biodiversity: Key Lessons from the Pan American Region

NASA Astrophysics Data System (ADS)

Kline, Keith L.; Martinelli, Fernanda Silva; Mayer, Audrey L.; Medeiros, Rodrigo; Oliveira, Camila Ortolan F.; Sparovek, Gerd; Walter, Arnaldo; Venier, Lisa A.

2015-12-01

Understanding how large-scale bioenergy production can affect biodiversity and ecosystems is important if society is to meet current and future sustainable development goals. A variety of bioenergy production systems have been established within different contexts throughout the Pan American region, with wide-ranging results in terms of documented and projected effects on biodiversity and ecosystems. The Pan American region is home to the majority of commercial bioenergy production and therefore the region offers a broad set of experiences and insights on both conflicts and opportunities for biodiversity and bioenergy. This paper synthesizes lessons learned focusing on experiences in Canada, the United States, and Brazil regarding the conflicts that can arise between bioenergy production and ecological conservation, and benefits that can be derived when bioenergy policies promote planning and more sustainable land-management systems. We propose a research agenda to address priority information gaps that are relevant to biodiversity concerns and related policy challenges in the Pan American region.

[Stanisława Adamowiczowa--first editor in-chief of Journal "Przeglad Epidemiologiczny"].

PubMed

Gromulska, Marta

2010-01-01

First issue of Epidemiological Review was published in 1920. First editor in chief was Stanisława Adamowiczowa, PhD (1888-1965), who had worked in National Central Epidemiological Institute since 1919, and later, for period of 45 years, interrupted by breaks resulting from political situation, worked in National Institute of Hygiene. In this jubilee article, we present scientific resume of S. Adamowiczowa which focuses on her achievements in infectious diseases epidemiology, and particularly in analysis and evaluation of current epidemiological data distribution in Poland and worldwide in the period. She was the pioneer in systemic organization of registries of new cases of diseases in the highly populated Polish cities; she initiated use of statistical methods in this field. As editor in chief of Epidemiological Review, she started publishing Epidemiological Chronicle, which is continuously added as a supplement to every second issue, each year. Name of S. Adamowiczowa is associated with Ludwik Rajchman--director of Hygiene Section in League of Nations, with Witold Chodźko PhD--she led courses in National School of Hygiene in Warsaw, with prof. Marcin Kacprzak--as co-author and co-editor of books on hygiene and epidemiology. A brief list of scientific publications of S. Adamowiczowa is also presented.

Genre Analysis of Decision Letters from Editors of Scientific Journals: Building on Flowerdew and Dudley-Evans (2002)

ERIC Educational Resources Information Center

Farley, Peter C.

2017-01-01

Flowerdew and Dudley-Evans (2002) described a prototypical structure for decision letters based on a personal database of letters written by one editor for the journal "English for Specific Purposes." In this article, I analyse a publicly available corpus of 59 decision letters from 48 different editors of a wide range of scientific…

FlaME: Flash Molecular Editor - a 2D structure input tool for the web

PubMed Central

2011-01-01

Background So far, there have been no Flash-based web tools available for chemical structure input. The authors herein present a feasibility study, aiming at the development of a compact and easy-to-use 2D structure editor, using Adobe's Flash technology and its programming language, ActionScript. As a reference model application from the Java world, we selected the Java Molecular Editor (JME). In this feasibility study, we made an attempt to realize a subset of JME's functionality in the Flash Molecular Editor (FlaME) utility. These basic capabilities are: structure input, editing and depiction of single molecules, data import and export in molfile format. Implementation The result of molecular diagram sketching in FlaME is accessible in V2000 molfile format. By integrating the molecular editor into a web page, its communication with the HTML elements on this page is established using the two JavaScript functions, getMol() and setMol(). In addition, structures can be copied to the system clipboard. Conclusion A first attempt was made to create a compact single-file application for 2D molecular structure input/editing on the web, based on Flash technology. With the application examples presented in this article, it could be demonstrated that the Flash methods are principally well-suited to provide the requisite communication between the Flash object (application) and the HTML elements on a web page, using JavaScript functions. PMID:21284863

Pan Am gets big savings at no cost

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanz, D.

Pan American World Airways' contract with an energy management control systems distributor enabled the company's terminal and maintenance facilities at JFK airport in New York to shift from housekeeping to major savings without additional cost. Energy savings from a pneumatic control system were split almost equally between Pan Am and Thomas S. Brown Associates (TSBA) Inc., and further savings are expected from a planned computer-controlled system. A full-time energy manager, able to give top priority to energy-consumption problems, was considered crucial to the program's success. Early efforts in light-level reduction and equipment scheduling required extensive persuasion and policing, but successfulmore » energy savings allowed the manager to progress to the more-extensive plants with TSBA.« less

An Investigation of Electrochemomechanical Actuation of Conductive Polyacrylonitrile (PAN) Nanofiber Composites

NASA Astrophysics Data System (ADS)

Gonzalez, Mark A.

A polymer-based nanofiber composite actuator designed for linear actuation was fabricated by electrospinning, actuated by electrolysis, and characterized by electrical and mechanical testing to address performance limitations and understand the activation processing effects on actuation performance. Currently, Electroactive polymers (EAPs) have provided uses in sensory and actuation technology, but have either low force output or expand rather than contract, falling short in capturing the natural motion and function of muscle desperately needed to provide breakthroughs in the bio-medical and robotic fields. Previous research has shown activated Polyacrylonitrile (PAN) fibers having biomimetic functionalities similar to the sarcomere contraction responsible for muscle function. Activated PAN is also known to contract and expand by electrolysis when in close vicinity to the anode and cathode, respectively. PAN nanofibers especially show faster response to changes in environmental pH and improved mechanical properties over larger diameter fibers. Conductive additives were introduced to the electrospinning solution and activated in an attempt to create composite PAN nanofiber gel actuators with improved conductivity and eliminate the need of stiff electrodes. Tensile testing was conducted to examine changes in mechanical properties between annealing and hydrolysis processing. Introducing conductive additives did not show a significant increase in conductivity and created unusable samples, requiring alternative electrode materials. Electrochemical contraction rates up to 25%/ min were achieved. Strains of 58.8%, ultimate stresses up to 77.1 MPa, and moduli of 0.21 MPa were achieved with pure PAN nanofiber mats, surpassing mechanical properties of natural muscles. Improvements to contraction rates and young's moduli are necessary to capture the function and performance of skeletal muscles properly.

Letter from the Editor

NASA Astrophysics Data System (ADS)

Strassmeier, Klaus G.

2008-01-01

As of 2006, Astronomische Nachrichten -- Astronomical Notes has reached its all-time high regarding the ISI journal impact factor, with an impressive increase of 60% compared to 2005. We now rank at position 1,399, as shown in the statistics below. This is solely due to the increased number and quality of published articles: In 2006, Astronomische Nachrichten -- Astronomical Notes published 208 research papers and received 1,033 citations -- five citations per paper on average. In 2007, we have published 177 research papers, and one may be curious to see how their factor will develop. In co-operation with Wiley InterScience we have achieved an average o nline publication time of just 4.5 months. As in the past, publication in Astronomische Nachrichten -- Astronomical Notes} continues to be free of charge. Also, all articles of the first issue of each volume can be downloaded free of charge, as can all articles labelled ``Editor's Choice'', which are additionally featured with a color image on the front cover.

Seasonal variation in pans in relation to limno-chemistry, size, hydroperiod, and river connectivity in a semi-arid subtropical region

NASA Astrophysics Data System (ADS)

Nhiwatiwa, Tamuka; Dalu, Tatenda

2017-02-01

Seasonal pans are hydrologically dynamic, with significant changes in water volume and depth in response to high evaporation, infiltration rates and inundation events. Intra-seasonal and inter-seasonal changes in endorheic and floodplain pans in relation to limnology, size, hydroperiod, and river connectivity were studied over two rainfall seasons across 36 pans at the Save Valley Conservancy. In the study region, floodplain pans were identified as pans that had connectivity with the Save River, while the endorheic pans (large and small) were hydrologically isolated basins. Seasonal trends for physico-chemical variables were initial low and gradual increased for both rainfall seasons. Significant inter-seasonal differences for several physico-chemical variables were observed. No significant differences in physico-chemical variables were observed between large and small endorheic pans, with the except for vegetation cover, which was higher in large pans. Floodplain pans differed from the endorheic systems in pH, conductivity, nutrients and suspended solids. Connectivity was found to be insignificant, as connections between these systems were probably too infrequent. Seasonal pans were uniquely distinguished by their morphometric, physico-chemical and hydrological characteristics. Inevitably, they are vulnerable to climate change with the extent of their resilience currently unknown.

Space Weather Editors in Transition: Hail and Farewell

NASA Astrophysics Data System (ADS)

Knipp, Delores J.

2017-02-01

I hope you will join me in welcoming Dr. Daniel Welling of University of Michigan and Dr. T. Paul O'Brien of the Aerospace Corporation to the Space Weather (SWE) editorial team. Dan and Paul have answered the call to fill the shoes of two departing editors: Dr. Howard Singer and Dr. Barbara Giles. Dan brings insight related to space weather model development, while Paul brings expertise in the geospace radiation environment.

A Comprehensive review on the open source hackable text editor-ATOM

NASA Astrophysics Data System (ADS)

Sumangali, K.; Borra, Lokesh; Suraj Mishra, Amol

2017-11-01

This document represents a comprehensive study of “Atom”, one of the best open-source code editors available with many features built-in to support multitude of programming environments and to provide a more productive toolset for developers.

The Pan-STARRS data server and integrated data query tool

NASA Astrophysics Data System (ADS)

Guo, Jhen-Kuei; Chen, Wen-Ping; Lin, Chien-Cheng; Chen, Ying-Tung; Lin, Hsing-Wen

2013-06-01

The Pan-STARRS project is operated by an international consortium. Located in Haleakala, Hawaii, the Pan-STARRS telescope system patrols the entire visible sky several times a month, with an aim to identify and characterize varying celestial objects of phenomena or in brightness (supernovae, novae, variable stars, etc) or in position (comets, asteroids, near-earth objects, X-planet etc.) PS1 science mission has started officially from May, 2010 and expects to end in the end of 2013. As of early 2012, every patch of sky observable from Hawaii has been observed in at least 5 bands (g', r', i', z', y') for 5 to 40 epochs. We have set up a data depository at NCU to serve the users in Taiwan. The massive amounts of Pan-STARRS data are downloaded via Internet from the Institute for Astronomy, University of Hawaii whenever new observations are obtained and processed. So far we have stored a total of 200 TB worth of data. In addition to star/galaxy catalogs, a postage stamp server provides access to FITS images. The Pan-STARRS Published Science Products Subsystem (PSPS) has recently passed its operational readiness, that provides users to query individual PS1 measurements. Here we present the data query tool to interface with the PS1 catalogs and postage stamp images, together with other complementary databases such as 2MASS and other data at IRSA (NASA/IPAC Infrared Science Archive).

Conflicts of interest in biomedical publications: considerations for authors, peer reviewers, and editors.

PubMed

Gasparyan, Armen Yuri; Ayvazyan, Lilit; Akazhanov, Nurbek A; Kitas, George D

2013-12-01

This article overviews evidence on common instances of conflict of interest (COI) in research publications from general and specialized fields of biomedicine. Financial COIs are viewed as the most powerful source of bias, which may even distort citation outcomes of sponsored publications. The urge to boost journal citation indicators by stakeholders of science communication is viewed as a new secondary interest, which may compromize the interaction between authors, peer reviewers and editors. Comprehensive policies on disclosure of financial and non-financial COIs in scholarly journals are presented as proxies of their indexing in evidence-based databases, and examples of successful medical journals are discussed in detail. Reports on clinical trials, systematic reviews, meta-analyses and clinical practice guidelines may be unduly influenced by author-pharmaceutical industry relations, but these publications do not always contain explicit disclosures to allow the readers to judge the reliability of the published conclusions and practice-changing recommendations. The article emphasizes the importance of adhering to the guidance on COI from learned associations such as the International Committee of Medical Journal Editors (ICMJE). It also considers joint efforts of authors, peer reviewers and editors as a foundation for appropriately defining and disclosing potential COIs.

Pan-STARRS Data Release 1

NASA Astrophysics Data System (ADS)

Flewelling, Heather

2017-01-01

We present an overview of the first and second Pan-STARRS data release (DR1 and DR2), and how to use the Published Science Products Subsystem (PSPS) and the Pan-STARRS Science Interface (PSI) to access the images and the catalogs. The data will be available from the STScI MAST archive. The PSPS is an SQLServer database that can be queried via script or web interface. This database has relative photometry and astrometry and object associations, making it easy to do searches across the entire sky as well as tools to generate lightcurves of individual objects as a function of time. Both releases of data use the 3pi survey, which has 5 filters (g,r,i,z,y), roughly 60 epochs (12 per filter) and covers 3/4 of the sky and everything north of -30 degrees declination. The first release of data (DR1) will contain stack images, mean attribute catalogs and static sky catalogs based off of the stacks. The second release of data (DR2) will contain the time domain data. For the images, this will include single exposures that have been detrended and warped. For the catalogs, this will include catalogs of all exposures as well as forced photometry.

An interactive editor for definition of touch-sensitive zones for a graphic display

NASA Technical Reports Server (NTRS)

Monroe, Burt L., III; Jones, Denise R.

1987-01-01

In the continuing effort to develop more efficient man-machine communications methods, touch displays have shown potential as straightforward input systems. The development of software necessary to handle such systems, however, can become tedious. In order to reduce the need for redundant programming, a touch editor has been developed which allows a programmer to interactively define touch-sensitive areas for a graphic display. The information produced during the editing process is written to a data file, which can be accessed easily when needed by an application program. This paper outlines the structure, logic, and use of the editor, as well as the hardware with which it is presently compatible.

29 CFR 793.11 - Combination announcer, news editor and chief engineer.

Code of Federal Regulations, 2010 CFR

2010-07-01

... editor and chief engineer. The 13(b)(9) exemption, as was made clear during the debate on the amendment... television stations. It is known at the time of such debate that these stations employ only a small number of...

29 CFR 793.11 - Combination announcer, news editor and chief engineer.

Code of Federal Regulations, 2011 CFR

2011-07-01

... editor and chief engineer. The 13(b)(9) exemption, as was made clear during the debate on the amendment... television stations. It is known at the time of such debate that these stations employ only a small number of...

Introduction of a pan-scan protocol for blunt trauma activations: what are the consequences?

PubMed

James, Melissa K; Schubl, Sebastian D; Francois, Michael P; Doughlin, Geoffrey K; Lee, Shi-Wen

2017-01-01

The aim of this study is to determine if the introduction of a pan-scan protocol during the initial assessment for blunt trauma activations would affect missed injuries, incidental findings, treatment times, radiation exposure, and cost. A 6-month prospective study was performed on patients with blunt trauma at a level 1 trauma center. During the last 3 months of the study, a pan-scan protocol was introduced to the trauma assessment. Categorical data were analyzed by Fisher exact test and continuous data were analyzed by Mann-Whitney nonparametric test. There were a total of 220 patients in the pre-pan-scan period and 206 patients during the pan-scan period. There was no significant difference in injury severity or mortality between the groups. Introduction of the pan-scan protocol substantially reduced the incidence of missed injuries from 3.2% to 0.5%, the length of stay in the emergency department by 68.2 minutes (95% confidence interval [CI], -134.4 to -2.1), and the mean time to the first operating room visit by 1465 minutes (95% CI, -2519 to -411). In contrast, fixed computed tomographic scan cost increased by $48.1 (95% CI, 32-64.1) per patient; however, total radiology cost per patient decreased by $50 (95% CI, -271.1 to 171.4). In addition, the rate of incidental findings increased by 14.4% and the average radiation exposure per patient was 8.2 mSv (95% CI, 5.0-11.3) greater during the pan-scan period. Although there are advantages to whole-body computed tomography, elucidation of the appropriate blunt trauma patient population is warranted when implementing a pan-scan protocol. Copyright © 2016 Elsevier Inc. All rights reserved.

Application of streptavidin mass spectrometric immunoassay tips for immunoaffinity based antibody phage display panning.

PubMed

Chin, Chai Fung; Ler, Lian Wee; Choong, Yee Siew; Ong, Eugene Boon Beng; Ismail, Asma; Tye, Gee Jun; Lim, Theam Soon

2016-01-01

Antibody phage display panning involves the enrichment of antibodies against specific targets by affinity. In recent years, several new methods for panning have been introduced to accommodate the growing application of antibody phage display. The present work is concerned with the application of streptavidin mass spectrometry immunoassay (MSIA™) Disposable Automation Research Tips (D.A.R.T's®) for antibody phage display. The system was initially designed to isolate antigens by affinity selection for mass spectrometry analysis. The streptavidin MSIA™ D.A.R.T's® system allows for easy attachment of biotinylated target antigens on the solid surface for presentation to the phage library. As proof-of-concept, a domain antibody library was passed through the tips attached with the Hemolysin E antigen. After binding and washing, the bound phages were eluted via standard acid dissociation and the phages were rescued for subsequent panning rounds. Polyclonal enrichment was observed for three rounds of panning with five monoclonal domain antibodies identified. The proposed method allows for a convenient, rapid and semi-automated alternative to conventional antibody panning strategies. Copyright © 2015 Elsevier B.V. All rights reserved.

What do PANs Tell us about VOC-NOx Photochemistry in the Urban/Rural Interface?

NASA Astrophysics Data System (ADS)

Roberts, J. M.; Flocke, F. M.; Zheng, W.; Bertman, S.; Marchewka, M.; Williams, E.; Lerner, B.; Kuster, W.; Goldan, P.; Gilman, J.; Sommariva, R.; Trainer, M.; Fehsenfeld, F.

2006-12-01

Peroxycarboxylic Nitric Anhydrides (PANs) are co-products of the VOC-NOx photochemistry that is responsible for O3 and secondary organic aerosol (SOA) formation in the troposphere. The relative abundance of the various PAN type compounds can provide important diagnostic information as to the contribution of different VOC sources to these processes. Anthropogenic, biogenic and petrochemical VOC sources have shown distinct profiles of PAN, PPN, MPAN, PiBN, and APAN, which can be analyzed using simple numerical models and compared to the results of detailed chemical mechanisms. One result of these studies is that the PAN compounds can be used to better define the contribution of isoprene to O3 production in the urban/rural interface. Another result is that high relative concentrations of APAN are characteristic of high petrochemical source impact. In addition, changes in the relative abundance of PPN and PAN can indicate the aging of a continental photochemical plume. This paper will present selected results from five field experiments and modeling studies from the Nashville 1999 Southern Oxidant Study up through the TexAQS 2006 study, in and around Houston, TX.

Does early care affect joint attention in great apes (Pan troglodytes, Pan paniscus, Pongo abelii, Pongo pygmaeus, Gorilla gorilla)?

PubMed

Pitman, Caisie A; Shumaker, Robert W

2009-08-01

The ability to share attention with another is the foundation on which other theory of mind skills are formed. The quality of care received during infancy has been correlated with increased joint attention in humans. The purpose of this study was to assess the effects of care style (responsive or basic) and caregiver type (ape or human) during the first 6 months on joint attention in 4 great ape species (Pan troglodytes, Gorilla gorilla, Pongo spp., and Pan pansicus). Great apes engaged in joint attention with conspecifics and humans regardless of the style of early care they experienced from either a great ape mother or human caregiver. This finding suggests that joint attention is a robust ability in great apes that is resilient against at least some differences in early care. Future studies using additional measures of early care quality are recommended. Copyright 2009 APA, all rights reserved.

PREFACE: 17th Pan-American Synchrotron Radiation Instrumentation Conference SRI2013

NASA Astrophysics Data System (ADS)

Williams, Gwyn P.; Revesz, Peter; Arp, Uwe

2014-03-01

These proceedings are a collection of the articles presented at the seventeenth Pan-American Synchrotron Radiation Instrumentation Conference SRI2013, held on the campus of the National Institute of Standards and Technology (NIST), located in Gaithersburg, Maryland, United States of America, 19-21 June, 2013. SRI2013 was jointly hosted by the Cornell University Cornell High Energy Synchrotron Source (CHESS), the Thomas Jefferson National Accelerator Facility (Jefferson Lab), and the Synchrotron Ultraviolet Radiation Facility (SURF III) at NIST. This meeting's focus was clearly on instrumentation, thus fulfilling the intent of this SRI meeting series, which was initiated at NIST, then the National Bureau of Standards (NBS), in 1979. SRI2013 hosted more than 150 delegates, despite the new US governmental travel restrictions. This proceedings series aims to be an essential reference work for practitioners in the field. It primarily documents the evolution and development of techniques, but also recent scientific advances, that were presented during the two and a half days of the conference. We are extremely thankful to all the authors who contributed to making these proceedings a volume of reference as well as to the reviewers for their careful reading and constructive recommendations for improving the articles. Great thanks go to Robert Dragoset at NIST, for creating and maintaining the conference website and generating the conference logo. We are also thankful for the excellent support we received from the Conference Program at NIST, especially Kathy Kilmer and Angela Ellis. And we would like to dedicate these proceedings to the memory of Kathy Kilmer, who passed away on 15 October, 2013. NIST will not be the same without her. The Co-Editors: Uwe Arp (SURF/NIST) Peter Reversz (CHESS) Gwyn P Williams (Jefferson Lab)

Publishing datasets with eSciDoc and panMetaDocs

NASA Astrophysics Data System (ADS)

Ulbricht, D.; Klump, J.; Bertelmann, R.

2012-04-01

Currently serveral research institutions worldwide undertake considerable efforts to have their scientific datasets published and to syndicate them to data portals as extensively described objects identified by a persistent identifier. This is done to foster the reuse of data, to make scientific work more transparent, and to create a citable entity that can be referenced unambigously in written publications. GFZ Potsdam established a publishing workflow for file based research datasets. Key software components are an eSciDoc infrastructure [1] and multiple instances of the data curation tool panMetaDocs [2]. The eSciDoc repository holds data objects and their associated metadata in container objects, called eSciDoc items. A key metadata element in this context is the publication status of the referenced data set. PanMetaDocs, which is based on PanMetaWorks [3], is a PHP based web application that allows to describe data with any XML-based metadata schema. The metadata fields can be filled with static or dynamic content to reduce the number of fields that require manual entries to a minimum and make use of contextual information in a project setting. Access rights can be applied to set visibility of datasets to other project members and allow collaboration on and notifying about datasets (RSS) and interaction with the internal messaging system, that was inherited from panMetaWorks. When a dataset is to be published, panMetaDocs allows to change the publication status of the eSciDoc item from status "private" to "submitted" and prepare the dataset for verification by an external reviewer. After quality checks, the item publication status can be changed to "published". This makes the data and metadata available through the internet worldwide. PanMetaDocs is developed as an eSciDoc application. It is an easy to use graphical user interface to eSciDoc items, their data and metadata. It is also an application supporting a DOI publication agent during the process of

Campylobacter in chicken livers and their destruction by pan frying.

PubMed

Whyte, R; Hudson, J A; Graham, C

2006-12-01

To enumerate Campylobacter spp. on the external surface and internal portions of chicken livers, and to assess the cooking required to inactivate naturally present cells. Of 30 livers tested all yielded Campylobacter spp. on their surfaces and 90% were found to contain the organism in internal tissue. Four (13%) livers contained >10(4) MPN campylobacters, and an additional seven (23%) contained >10(3) MPN campylobacters per liver. The internal temperature of pan-fried livers under the conditions used reached a maximum of 70-80 degrees C, and maintaining this temperature for 2-3 min was necessary to inactivate naturally occurring Campylobacter spp. All isolates identified were either C. jejuni or C. coli. Chicken livers represent a potential source of human campylobacteriosis as they contained >10(4) MPN per liver in 13% of the samples tested. Pan-frying can produce an acceptable product that is safe to eat. SIGNIFICANCE AND IMPACT OF THIS STUDY: The data provided can be used in exposure assessments of Campylobacter in poultry products in terms of both quantitative data and assessing pan-frying and its ability to destroy campylobacters.

Geometric morphometric analysis of mandibular shape diversity in Pan.

PubMed

Robinson, Chris

2012-07-01

The aim of this research is to determine whether geometric morphometric (GM) techniques can provide insights into how the shape of the mandibular corpus differs between bonobos and chimpanzees and to explore the potential implications of those results for our understanding of hominin evolution. We focused on this region of the mandible because of the relative frequency with which it has been recovered in the hominin fossil record. In addition, no previous study had explored in-depth three-dimensional (3D) mandibular corpus shape differences between adults of the two Pan species using geometric morphometrics. GM methods enable researchers to quantitatively analyze and visualize 3D shape changes in skeletal elements and provide an important compliment to traditional two-dimensional analyses. Eighteen mandibular landmarks were collected using a Microscribe 3DX portable digitizer. Specimen configurations were superimposed using Generalized Procrustes analysis and the projections of the fitted coordinates to tangent space were analyzed using multivariate statistics. The size-adjusted corpus shapes of Pan paniscus and Pan troglodytes could be assigned to species with approximately 93% accuracy and the Procrustes distance between the two species was significant. Analyses of the residuals from a multivariate linear regression of the data on centroid size suggested that much of the shape difference between the species is size-related. Chimpanzee subspecies and a small sample of Australopithecus specimens could be correctly identified to taxon, at best, only 75% of the time, although the Procrustes distances between these taxa were significant. The shape of the mandibular symphysis was identified as especially useful in differentiating Pan species from one another. This suggests that this region of the mandible has the potential to be informative for taxonomic analyses of fossil hominoids, including hominins. The results also have implications for phylogenetic hypotheses of

Evolution of the ATLAS PanDA Production and Distributed Analysis System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maeno, T.; De, K.; Wenaus, T.

2012-12-13

Evolution of the ATLAS PanDA Production and Distributed Analysis System T Maeno1,5, K De2, T Wenaus1, P Nilsson2, R Walker3, A Stradling2, V Fine1, M Potekhin1, S Panitkin1 and G Compostella4 Published under licence by IOP Publishing Ltd Journal of Physics: Conference Series, Volume 396, Part 3 Article PDF References Citations Metrics 101 Total downloads Cited by 8 articles Turn on MathJax Share this article Article information Abstract The PanDA (Production and Distributed Analysis) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at LHC data processing scale. PanDAmore » has performed well with high reliability and robustness during the two years of LHC data-taking, while being actively evolved to meet the rapidly changing requirements for analysis use cases. We will present an overview of system evolution including automatic rebrokerage and reattempt for analysis jobs, adaptation for the CernVM File System, support for the multi-cloud model through which Tier-2 sites act as members of multiple clouds, pledged resource management and preferential brokerage, and monitoring improvements. We will also describe results from the analysis of two years of PanDA usage statistics, current issues, and plans for the future.« less

The ExoMars PanCam Instrument

NASA Astrophysics Data System (ADS)

Griffiths, Andrew; Coates, Andrew; Muller, Jan-Peter; Jaumann, Ralf; Josset, Jean-Luc; Paar, Gerhard; Barnes, David

2010-05-01

The ExoMars mission has evolved into a joint European-US mission to deliver a trace gas orbiter and a pair of rovers to Mars in 2016 and 2018 respectively. The European rover will carry the Pasteur exobiology payload including the 1.56 kg Panoramic Camera. PanCam will provide multispectral stereo images with 34 deg horizontal field-of-view (580 microrad/pixel) Wide-Angle Cameras (WAC) and (83 microrad/pixel) colour monoscopic "zoom" images with 5 deg horizontal field-of-view High Resolution Camera (HRC). The stereo Wide Angle Cameras (WAC) are based on Beagle 2 Stereo Camera System heritage [1]. Integrated with the WACs and HRC into the PanCam optical bench (which helps the instrument meet its planetary protection requirements) is the PanCam interface unit (PIU); which provides image storage, a Spacewire interface to the rover and DC-DC power conversion. The Panoramic Camera instrument is designed to fulfil the digital terrain mapping requirements of the mission [2] as well as providing multispectral geological imaging, colour and stereo panoramic images and solar images for water vapour abundance and dust optical depth measurements. The High Resolution Camera (HRC) can be used for high resolution imaging of interesting targets detected in the WAC panoramas and of inaccessible locations on crater or valley walls. Additionally HRC will be used to observe retrieved subsurface samples before ingestion into the rest of the Pasteur payload. In short, PanCam provides the overview and context for the ExoMars experiment locations, required to enable the exobiology aims of the mission. In addition to these baseline capabilities further enhancements are possible to PanCam to enhance it's effectiveness for astrobiology and planetary exploration: 1. Rover Inspection Mirror (RIM) 2. Organics Detection by Fluorescence Excitation (ODFE) LEDs [3-6] 3. UVIS broadband UV Flux and Opacity Determination (UVFOD) photodiode This paper will discuss the scientific objectives and resource

EDITORIAL: New Editor-in-Chief for Nanotechnology New Editor-in-Chief for Nanotechnology

NASA Astrophysics Data System (ADS)

Couzin, Nina

2009-01-01

Nanotechnology is proud to announce the appointment of Professor Mark Reed, Yale University, as the new Editor-in-Chief from January 2009. Mark Reed holds the Harold Hodgkinson Chair of Engineering and Applied Science at Yale University. He has made significant contributions in the areas of quantum dots, electronic transport in nanoscale and mesoscopic systems, artificially structured materials and devices, and molecular electronics. Professor Reed has been associated with the journal as an Editorial Board member for a number of years and we are delighted that he has agreed to take on the scientific leadership of the journal in its 20th year. We also take the opportunity to thank Professor Mark Welland, Cambridge University, for his work as Editor-in-Chief since 2001, and for presiding over the re-launch and remarkable growth of the journal since then. Nanotechnology is unique in that it was the first peer-reviewed journal in the area of nanoscience, the first issue appearing in 1990. Since then it has established a distinguished publication record and has become a leading journal covering all aspects of nanoscale science and technology, as well as specializing in in-depth, comprehensive articles not seen in letter format journals. Published weekly and featuring subject sections, the journal is truly multidisciplinary in nature and is an excellent medium to quickly deliver your research results to readers worldwide. Nanotechnology is proud to be offering some of the fastest publication times around (less than three months on average from receipt to online publication). We offer free online access to all published papers for 30 days, ensuring that anyone with access to the internet will be able to read your paper. We were also the first journal to give our authors the opportunity to communicate their research to a wider audience through nanotechweb.org and other IOP websites. See the journal's homepage at www.iop.org/Journals/nano for more details. We are looking

Comparison of PAN and Black Carbon Levels in Mexico City: 1997 and 2003

NASA Astrophysics Data System (ADS)

Gaffney, J. S.; Marley, N. A.

2004-12-01

Peroxyacetyl nitrate (PAN) is a secondary oxidant formed by the oxidation of hydrocarbons in the presence of nitrogen dioxide. PAN is a good indicator compound for hydrocarbon reactivity that leads to ozone formation. Black carbon (BC) is formed by incomplete combustion processes such as diesel soot formation and is a good indicator of primary carbonaceous aerosols in urban areas. We used a fast-response luminol method to measure PAN and BC during the Mexico City Metropolitan Area 2003/Mexico City Megacity 2003 field study in April 2003. We compare these results with our previous PAN measurements in Mexico City during February 1997, made with a gas chromatograph-electron capture detector system. The decreased PAN levels observed in 2003 are consistent with the application of emissions controls on spark ignition gasoline-fueled vehicles, leading to lower levels of the nitrogen oxides and reactive volatile hydrocarbons needed to form PAN. Black carbon data for Mexico City in 2003, taken with a seven-channel aethalometer, are compared with data from 1997, estimated from thermal analyses as elemental carbon (EC). The comparison indicates little change in the levels of BC/EC over the six-year period. This observation is consistent with the application of minimal controls to diesel engines, the likely major source of BC in the Mexico City megacity complex during this period. The authors wish to thank the researchers at Centro Nacional de Investigación en Calidad Ambiental (CENICA), Mexico City. This work was supported by the U.S. Department of Energy, Atmospheric Science Program. We also wish to acknowledge Drs. Mario and Luisa Molina for their help in organizing and directing the Mexico City Metropolitan Area 2003 field study, during which these data were collected.

[Co-editors and editors with Jewish origins of the first German journals for anaesthesia. Their fate under National Socialism and an attempt at a biographical appreciation].

PubMed

Goerig, M; Goetz, A E

2010-09-01

The decision to publish the journals Der Schmerz and Narkose und Anaesthesie in 1928 was an important step towards the professionalization of anaesthesiology in Germany. The appearance of both journals, which for economic reasons merged into Schmerz - Narkose - Anaesthesie 1 year later, was initiated and vehemently supported by Jewish physicians. As editors and co-editors they were deeply involved with the editorial tasks of the journals for years from the early beginnings. When the National Socialistic Party took over the government in Germany many of the Jewish colleagues were forced to quit their editorial tasks, were eliminated and replaced by "Arians", they were persecuted and often arrested, forced to emigrate or decided to commit suicide due to inhumane personal circumstances. It is our intention to recall the biography and the terrible fate of the nearly unknown Jewish members of the editorial board of the first German anaesthesia journals. Moreover the biographic sketches promote a continuous discussion about the victims of an inhumane and barbarous ideology.

SOPanG: online text searching over a pan-genome.

PubMed

Cislak, Aleksander; Grabowski, Szymon; Holub, Jan

2018-06-22

The many thousands of high-quality genomes available nowadays imply a shift from single genome to pan-genomic analyses. A basic algorithmic building brick for such a scenario is online search over a collection of similar texts, a problem with surprisingly few solutions presented so far. We present SOPanG, a simple tool for exact pattern matching over an elastic-degenerate string, a recently proposed simplified model for the pan-genome. Thanks to bit-parallelism, it achieves pattern matching speeds above 400MB/s, more than an order of magnitude higher than of other software. SOPanG is available for free from: https://github.com/MrAlexSee/sopang. Supplementary data are available at Bioinformatics online.

A new two-Dimensional Physical Basis for the Complementary Relation Between Terrestrial and pan Evaporation

NASA Astrophysics Data System (ADS)

Pettijohn, J. C.; Salvucci, G. D.

2008-12-01

Archived global measurements of water loss from evaporation pans constitute an important indirect measure of evaporative flux. Historical data from evaporation pans shows a decreasing trend over the last half century, but the relationship between pan evaporation and moisture-limited terrestrial evaporation is complex, leading to ambiguities in the interpretation of this data. Under energy-limited conditions, pan evaporation (Epan) and moisture-limited terrestrial evaporation (E) increase or decrease together, while in moisture- limited conditions these fluxes form a complementary relation in which increases in one rate accompany decreases in the other. This has lead to debate about the meaning of the observed trends in the context of changing climate. Here a two-dimensional numerical model of a wet pan in a drying landscape is used to demonstrate that, over a wide range of realistic atmospheric and surface conditions, the influence that changes in E have on Epan (1) are complementary and linear, (2) do not depend upon surface wind speed, and (3) are strikingly asymmetrical, in that a unit decrease in E causes approximately a five-fold increase in Epan, as found in a recent analysis of daily evaporation from US grasslands (Kahler and Brutsaert, 2006). Previous attempts to explain the CR have been based on one dimensional diffusion and energy balance arguments, leading to analytic solutions based on Penman-type bulk difference equations. But without acknowledging the spatially complex multidimensional humidity and temperature field around the pan, and specifically how these fields change as the contrast between the wet pan and the drying land surface increases, such integrated bulk difference equations are a priori incomplete (they ignore important divergence terms), and thus these explanations must be considered physically incomplete. Results of the present study improve the theoretical foundation of the CR, thus increasing the reliability with which it can be

Multi-sensor fusion of Landsat 8 thermal infrared (TIR) and panchromatic (PAN) images.

PubMed

Jung, Hyung-Sup; Park, Sung-Whan

2014-12-18

Data fusion is defined as the combination of data from multiple sensors such that the resulting information is better than would be possible when the sensors are used individually. The multi-sensor fusion of panchromatic (PAN) and thermal infrared (TIR) images is a good example of this data fusion. While a PAN image has higher spatial resolution, a TIR one has lower spatial resolution. In this study, we have proposed an efficient method to fuse Landsat 8 PAN and TIR images using an optimal scaling factor in order to control the trade-off between the spatial details and the thermal information. We have compared the fused images created from different scaling factors and then tested the performance of the proposed method at urban and rural test areas. The test results show that the proposed method merges the spatial resolution of PAN image and the temperature information of TIR image efficiently. The proposed method may be applied to detect lava flows of volcanic activity, radioactive exposure of nuclear power plants, and surface temperature change with respect to land-use change.

Theoretical evaluation of a V/STOL fighter model utilizing the PAN AIR code

NASA Technical Reports Server (NTRS)

Howell, G. A.; Bhateley, I. C.

1982-01-01

The PAN AIR computer code was investigated as a tool for predicting closely coupled aerodynamic and propulsive flowfields of arbitrary configurations. The NASA/Ames V/STOL fighter model, a configuration of complex geometry, was analyzed with the PAN AIR code. A successful solution for this configuration was obtained when the nozzle exit was treated as an impermeable surface and no wakes were included around the nozzle exit. When separated flow was simulated from the end of the nacelle, requiring the use of wake networks emanating from the nozzle exit, a number of problems were encountered. A circular body nacelle model was used to investigate various techniques for simulating the exhaust plume in PAN AIR. Several approaches were tested and eliminated because they could not correctly simulate the interference effects. Only one plume modeling technique gave good results. A PAN AIR computation that used a plume shape and inflow velocities obtained from the Navier-Stokes solution for the plume produced results for the effects of power that compared well with experimental data.

Sensor Package Pan and Tilt Unit on Atlantis during STS-132

NASA Image and Video Library

2010-05-15

S132-E-005110 (15 May 2010) --- While preparing for the routine inspection of Atlantis’ thermal protection system on Flight Day 2, the STS-132 crew discovered a cable was being pinched and preventing the sensor package pan and tilt unit from moving properly. There are alternate sensor packages that do not require the pan and tilt function; and personnel in the Johnson Space Center’s Mission Control Center are evaluating those procedures. Photo credit: NASA or National Aeronautics and Space Administration

Are the Editors faced with e-problems performing their duties and responsibilities satisfactorily?

PubMed

Ali Jawaid, Shaukat; Jawaid, Masood

2013-09-01

Astonishing revolution in information technology, developments in electronic publishing and availability of manuscript management software's has provided lot of facilities to authors, reviewers as well as editors but it has also given birth to lot of e-problems. This communication highlights some of these e-problems besides discussing the manuscript management system practiced by Pakistan Journal of Medical Sciences through modified Open Journal System. It also cautions the editors of small journals faced with financial and human resource constraints to keep themselves abreast of all these developments, go for automation in e publishing gradually as all the stake holders i.e. authors, reviewers and office management staff learns these and become used to it.

75 FR 13085 - Pan-Pacific Education and Communications Experiments by Satellite (PEACESAT): Closing Date

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-18

.... 100305127-0127-01] Pan-Pacific Education and Communications Experiments by Satellite (PEACESAT): Closing..., Public Law No. 111-117, the U.S. Department of Commerce announces the solicitation of applications for a grant for the Pan-Pacific Education and Communications Experiments by Satellite (PEACESAT) Program...

Measurements of peroxyacetyl nitrate (PAN) and peroxypropionyl nitrate (PPN) at selected urban, rural and remote sites

NASA Technical Reports Server (NTRS)

Singh, Hanwant B.; Salas, Louis J.

1989-01-01

PAN and PPN were measured in a series of eight field studies performed at urban, rural and remote locations in the contiguous U.S. during 1983-1985. Seven of the eight studies were performed in the winter/spring period, a period of sparsely available data. Nearly 2000 air samples were analyzed during these studies. Mean PAN and PPN levels in the range of 45-1600 ppt (max. 7.9 ppb) and 5-230 ppt (max. 0.9 ppb), respectively, were measured. Despite a great deal of observed variability, PAN and PPN showed virtually identical behavior at all sites and in all seasons, supporting the view that these nitrogenous compounds are produced and destroyed by very similar mechanisms. On the average PPN concentrations were about 8 percent (range 3-14 percent) of PAN values. It is inferred that PPN/PAN ratio is highest in urban areas and declines as polluted air masses are transported over long distances.

Partially-Averaged Navier-Stokes (PANS) approach for study of fluid flow and heat transfer characteristics in Czochralski melt

NASA Astrophysics Data System (ADS)

Verma, Sudeep; Dewan, Anupam

2018-01-01

The Partially-Averaged Navier-Stokes (PANS) approach has been applied for the first time to model turbulent flow and heat transfer in an ideal Czochralski set up with the realistic boundary conditions. This method provides variable level of resolution ranging from the Reynolds-Averaged Navier-Stokes (RANS) modelling to Direct Numerical Simulation (DNS) based on the filter control parameter. For the present case, a low-Re PANS model has been developed for Czochralski melt flow, which includes the effect of coriolis, centrifugal, buoyant and surface tension induced forces. The aim of the present study is to assess improvement in results on switching to PANS modelling from unsteady RANS (URANS) approach on the same computational mesh. The PANS computed results were found to be in good agreement with the reported experimental, DNS and Large Eddy Simulation (LES) data. A clear improvement in computational accuracy is observed in switching from the URANS approach to the PANS methodology. The computed results further improved with a reduction in the PANS filter width. Further the capability of the PANS model to capture key characteristics of the Czochralski crystal growth is also highlighted. It was observed that the PANS model was able to resolve the three-dimensional turbulent nature of the melt, characteristic flow structures arising due to flow instabilities and generation of thermal plumes and vortices in the Czochralski melt.

University-government relationships in the training of technical writers-editors

NASA Technical Reports Server (NTRS)

Stohrer, Freda F.; Pinelli, Thomas E.

1979-01-01

Traditional and nontraditional methods of training technical writers-editors are reviewed. Combining work experience with classroom instruction in the form of cooperative education provides a method of strengthening the Federal career service in professional occupations. The NASA Langley experience that successfully introduced students to the special demands of technical writing and editing is described.

Efficiency of malaise traps and colored pan traps for collecting flower visiting insects from three forested ecosystems

Treesearch

Joshua W. Campbell; J.L. Hanula

2007-01-01

Pan and Malaise traps have been used widely to sample insect abundance and diversity, but no studies have compared their performance for sampling pollinators in forested ecosystems. Malaise trap design and color of pan traps are important parameters that influence insect pollinator catches. We compared pan trap (blue, yellow, white, and red) and Malaise trap catches...

How Educators, Editors View Aspects of J School's Role in Press Criticism.

ERIC Educational Resources Information Center

Ryan, Michael

1978-01-01

A survey of newspaper editors and journalism school deans and faculty members revealed that media criticism by journalism schools occurs infrequently and that both academic and media people have mixed reactions about its advisability. (GW)

Conflicts of interest in biomedical publications: considerations for authors, peer reviewers, and editors

PubMed Central

Gasparyan, Armen Yuri; Ayvazyan, Lilit; Akazhanov, Nurbek A.; Kitas, George D.

2013-01-01

This article overviews evidence on common instances of conflict of interest (COI) in research publications from general and specialized fields of biomedicine. Financial COIs are viewed as the most powerful source of bias, which may even distort citation outcomes of sponsored publications. The urge to boost journal citation indicators by stakeholders of science communication is viewed as a new secondary interest, which may compromize the interaction between authors, peer reviewers, and editors. Comprehensive policies on disclosure of financial and non-financial COIs in scholarly journals are presented as proxies of their indexing in evidence-based databases, and examples of successful medical journals are discussed in detail. Reports on clinical trials, systematic reviews, meta-analyses, and clinical practice guidelines may be unduly influenced by author-pharmaceutical industry relations, but these publications do not always contain explicit disclosures to allow the readers to judge the reliability of the published conclusions and practice-changing recommendations. The article emphasizes the importance of adhering to the guidance on COI from learned associations such as the International Committee of Medical Journal Editors (ICMJE). It also considers joint efforts of authors, peer reviewers, and editors as a foundation for appropriately defining and disclosing potential COIs. PMID:24382859

PanDA: Exascale Federation of Resources for the ATLAS Experiment at the LHC

NASA Astrophysics Data System (ADS)

Barreiro Megino, Fernando; Caballero Bejar, Jose; De, Kaushik; Hover, John; Klimentov, Alexei; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Padolski, Siarhei; Panitkin, Sergey; Petrosyan, Artem; Wenaus, Torre

2016-02-01

After a scheduled maintenance and upgrade period, the world's largest and most powerful machine - the Large Hadron Collider(LHC) - is about to enter its second run at unprecedented energies. In order to exploit the scientific potential of the machine, the experiments at the LHC face computational challenges with enormous data volumes that need to be analysed by thousand of physics users and compared to simulated data. Given diverse funding constraints, the computational resources for the LHC have been deployed in a worldwide mesh of data centres, connected to each other through Grid technologies. The PanDA (Production and Distributed Analysis) system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, Cloud Computing and HPC. It is currently running steadily up to 200 thousand simultaneous cores (limited by the available resources for ATLAS), up to two million aggregated jobs per day and processes over an exabyte of data per year. The success of PanDA in ATLAS is triggering the widespread adoption and testing by other experiments. In this contribution we will give an overview of the PanDA components and focus on the new features and upcoming challenges that are relevant to the next decade of distributed computing workload management using PanDA.

Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

PubMed Central

Gaughan, Thomas; Buckley, Ashura; Hommer, Rebecca; Grant, Paul; Williams, Kyle; Leckman, James F.; Swedo, Susan E.

2016-01-01

Study Objectives: Polysomnographic investigation of sleep architecture in children presenting with pediatric acute-onset neuropsychiatric syndrome (PANS). Methods: Fifteen consecutive subjects meeting criteria for PANS (mean age = 7.2 y; range 3–10 y) underwent single-night full polysomnography (PSG) read by a pediatric neurologist. Results: Thirteen of 15 subjects (87%) had abnormalities detected with PSG. Twelve of 15 had evidence of rapid eye movement (REM) sleep motor disinhibition, as characterized by excessive movement, laughing, hand stereotypies, moaning, or the continuation of periodic limb movements during sleep (PLMS) into REM sleep. Conclusions: This study shows various forms of REM sleep motor disinhibition present in a population of children with PANS. Citation: Gaughan T, Buckley A, Hommer R, Grant P; Williams K, Leckman JF, Swedo SE. Rapid eye movement sleep abnormalities in children with pediatric acute-onset neuropsychiatric syndrome (PANS). J Clin Sleep Med 2016;12(7):1027–1032. PMID:27166296

Chromato-panning: an efficient new mode of identifying suitable ligands from phage display libraries

PubMed Central

Noppe, Wim; Plieva, Fatima; Galaev, Igor Yu; Pottel, Hans; Deckmyn, Hans; Mattiasson, Bo

2009-01-01

Background Phage Display technology is a well established technique for high throughput screening of affinity ligands. Here we describe a new compact chromato-panning procedure for selection of suitable binders from a phage peptide display library. Results Both phages and E. coli cells pass non-hindered through the interconnected pores of macroporous gel, so called cryogel. After coupling a ligand to a monolithic cryogel column, the phage library was applied on the column and non-bound phages were washed out. The selection of strong phage-binders was achieved already after the first panning cycle due to the efficient separation of phage-binders from phage-non-binders in chromatographic mode rather than in batch mode as in traditional biopanning procedures. E. coli cells were applied on the column for infection with the specifically bound phages. Conclusion Chromato-panning allows combining several steps of the panning procedure resulting in 4–8 fold decrease of total time needed for phage selection. PMID:19292898

Letter from the Editor

NASA Astrophysics Data System (ADS)

Strassmeier, Klaus G.

2009-01-01

As of 2007, Astronomische Nachrichten -- Astronomical Notes has reached its all-time high regarding the ISI journal impact factor, with an impressive increase of 60% compared to 2005. We now rank at 1,461, as shown in the statistics below. This is solely due to the increased quality of the published articles: In 2006, Astronomische Nachrichten -- Astronomical Notes published 208 research papers and received 1,033 citations -- five citations per paper on average. In 2007, we have published 177 research papers with roughly the same number of citations. In co-operation with Wiley InterScience we have achieved an average online publication time of just 4.5 months. We hope that the year 2008 will be comparably prosperous. As in the past, publication in Astronomische Nachrichten -- Astronomical Notes continues to be free of charge. Also, all articles of the first issue of each volume can be downloaded free of charge, as can all articles labelled ``Editor's Choice'', which are additionally featured with a color image on the front cover.

Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions

PubMed Central

Tucci, Serena; de Manuel, Marc; Ghirotto, Silvia; Benazzo, Andrea; Prado-Martinez, Javier; Lorente-Galdos, Belen; Nam, Kiwoong; Dabad, Marc; Hernandez-Rodriguez, Jessica; Comas, David; Navarro, Arcadi; Schierup, Mikkel H.; Andres, Aida M.; Barbujani, Guido; Hvilsom, Christina; Marques-Bonet, Tomas

2016-01-01

The genus Pan is the closest genus to our own and it includes two species, Pan paniscus (bonobos) and Pan troglodytes (chimpanzees). The later is constituted by four subspecies, all highly endangered. The study of the Pan genera has been incessantly complicated by the intricate relationship among subspecies and the statistical limitations imposed by the reduced number of samples or genomic markers analyzed. Here, we present a new method to reconstruct complete mitochondrial genomes (mitogenomes) from whole genome shotgun (WGS) datasets, mtArchitect, showing that its reconstructions are highly accurate and consistent with long-range PCR mitogenomes. We used this approach to build the mitochondrial genomes of 20 newly sequenced samples which, together with available genomes, allowed us to analyze the hitherto most complete Pan mitochondrial genome dataset including 156 chimpanzee and 44 bonobo individuals, with a proportional contribution from all chimpanzee subspecies. We estimated the separation time between chimpanzees and bonobos around 1.15 million years ago (Mya) [0.81–1.49]. Further, we found that under the most probable genealogical model the two clades of chimpanzees, Western + Nigeria-Cameroon and Central + Eastern, separated at 0.59 Mya [0.41–0.78] with further internal separations at 0.32 Mya [0.22–0.43] and 0.16 Mya [0.17–0.34], respectively. Finally, for a subset of our samples, we compared nuclear versus mitochondrial genomes and we found that chimpanzee subspecies have different patterns of nuclear and mitochondrial diversity, which could be a result of either processes affecting the mitochondrial genome, such as hitchhiking or background selection, or a result of population dynamics. PMID:27345955

Surface properties of poly(acrylonitrile) (PAN) precipitation polymerized in supercritical CO2 and the influence of the molecular weight.

PubMed

Shen, Qing; Gu, Qing-Feng; Hu, Jian-Feng; Teng, Xin-Rong; Zhu, Yun-Feng

2003-11-15

In this paper, the surface properties, e.g., the total surface free energy and the related Lifshitz-van der Waals and Lewis acid-base components, of polyacrylonitrile (PAN) precipitation polymerized in supercritical CO(2) have been characterized. Moreover, the influence of molecular weight varying has been also investigated. Results show that the surface properties of PAN resulting from supercritical CO(2) are different from those obtained by the conventional method. Of these data, one important finding is that the supercritical CO(2) PAN seems to decrease the surface free energy with the increased molecular weight. Based on previous recorded NMR spectra of this PAN and especially compared to commercial PAN, such phenomena are discussed and ascribed to an increase of the H-bonds and a reduction of the isotacticity in the supercritical CO(2) condition for PAN.

Does pan diameter influence carbon monoxide levels during heating of water to boiling point with a camping stove?

PubMed

Leigh-Smith, Simon; Stevenson, Richard; Watt, Martin; Watt, Ian; McFadyen, Angus; Grant, Stan

2004-01-01

To determine whether pan diameter influences carbon monoxide (CO) concentration during heating of water to boiling point with a camping stove. The hypothesis was that increasing pan diameter increases CO concentration because of greater flame dispersal and a larger flame. This was a randomized, prospective study. A Coleman Dual Fuel 533 stove was used to heat pans of water to boiling point, with CO concentration monitored every 30 seconds for 5 minutes. The stove was inside a partially ventilated 200-L cardboard box model that was inside an environmental chamber at -6 degrees C. Water temperature, water volume, and flame characteristics were all standardized. Ten trials were performed for each of 2 pan diameters (base diameters of 165 mm [small] and 220 mm [large]). There was a significant difference (P = .002) between the pans for CO levels at each measurement interval from 60 seconds onward. These differences were markedly larger after 90 seconds, with a mean difference of 185 ppm (95% CI 115, 276 ppm) for all the results from 120 seconds onwards. This study has shown that there is significantly higher CO production with a large-diameter pan compared with a small-diameter pan. These findings were evident by using a camping stove to heat water to boiling point when a maximum blue flame was present throughout. Thus, in enclosed environments it is recommended that small-diameter pans be used in an attempt to prevent high CO levels.

EDITORIAL: Letter from the Editor Letter from the Editor

NASA Astrophysics Data System (ADS)

Pashinin, Pavel P.

2013-01-01

Dear readers, contributors, and members of the world laser physics community. It is a great honour for us to introduce to you our new publishing partner, IOP Publishing, a subsidiary of the Institute of Physics, United Kingdom. IOP Publishing is a world renowned authority in producing journals, magazines, websites and services that enable researchers and research organizations to present their work to a world-wide audience. Laser Physics, the first English-language scientific journal in Russia, was founded in 1990 on the initiative of Alexander M Prokhorov, a pioneer and leader in laser physics research. Professor Prokhorov served as the first Editor-in-Chief of the journal until 2002. We are proud that it is our 23rd year of publishing Laser Physics and our 10th year of publishing Laser Physics Letters. We would like to honour the memory of our friend, late Professor Igor Yevseyev, whose enthusiasm and unwavering dedication to our journals contributed most significantly to their success. It was initially his idea in 2011 to approach IOP with a partnership proposal. We deeply regret that he is no longer with us as we enter this productive alliance. Now, in partnership with IOP, we are turning a new page in providing world-wide access to the cutting-edge research results in our journals, serving our well established global audience. We see new horizons opening for our journals for years to come and hope that our readers share our enthusiasm and aspirations. Please accept our best wishes for all your new scientific endeavors in the exciting field of laser physics.

Conflicts of interest for medical publishers and editors: protecting the integrity of scientific scholarship.

PubMed

Desai, Sapan S; Shortell, Cynthia K

2011-09-01

Competition of interest may exist at all levels in the medical publication process. Ensuring the integrity of scientific scholarship involves protecting editorial independence, promoting the use of scientific arbitration boards, promoting transparency throughout all stages of publication, and protecting the relationship between the publisher and its editors through an effective legal framework. It is incumbent upon the publisher, editors, authors, and readers to ensure that the highest standards of scientific scholarship are upheld. Doing so will help reduce fraud and misrepresentation in medical research and increase the trustworthiness of landmark findings in science. Copyright © 2011 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

Visions of Students Today: A Message from the Editors

ERIC Educational Resources Information Center

Wentzell, G. W.; Richlin, L.; Cox. M. D.

2012-01-01

In Michael Wesch's (2007) now widely seen video "A Vision of Students Today" (http://www.youtube.com/watch?v=dGCJ46vyR9o), a camera pans across a large, traditional classroom where college students hold up messages about themselves as members of the current generation of learners, who have been dubbed Millennials (Howe & Strauss, 2000). The video…

Gerhart Panning (1900-1944): a German forensic pathologist and his involvement in Nazi crimes during Second World War.

PubMed

Preuss, Johanna; Madea, Burkhard

2009-03-01

Twenty years after the Second World War the public were made aware of War Crimes committed by the German forensic pathologist, Gerhart Panning (1900-1944). From 1942 till 1944, Panning was professor at the Institute of Forensic Medicine at the University of Bonn. Panning died of tuberculosis on 22 March 1944. After the Second World War, Panning's widow tried to obtain denazification for her husband. There were no particularly serious doubts. In 1965, Konrad Graf von Moltke, the son of Helmuth James Graf von Moltke (1907-1944), presented to the court a private letter from his father to his mother. In this letter, written in 1941, Panning's experiments on Soviet prisoners are described. In the so-called Callsen trial in the court of Darmstadt from 1960 to 1968, the experiments were confirmed by witnesses. In 1941, Panning performed experiments in cooperation with the Sicherheitsstaffel (Nazi special police) in the Ukraine to prove that captured ammunition of the soviet infantry violated international law. For this purpose, different parts of the bodies of living Soviets were used as firing targets. He published the results of these experiments in a scientific journal without any evidence of the origin of these observations. In this article, Panning's life and crimes have been described.

John F. Dewey—Tectonics Editor

NASA Astrophysics Data System (ADS)

Richman, Barbara T.

‘I want the journal to acquire a reputation for very rapid, fair, and accurate reviewing,’ asserted John F. Dewey, editor-in-chief of AGU's newest journal, Tectonics. Dewey said that he will rule the bimonthly, which will begin publication in February, ‘with a bit of a rod of iron’ to ensure that Tectonics is ‘where only original and important papers are published.’‘I'm going to be very strict with reviewers,’ Dewey explained in his quick British clip. ‘If the review does not come back to me within 10 days to 2 weeks, I'll review the paper myself. I'm also going to have a system whereby, if a paper needs major surgery after being refereed, it will be rejected. Papers will have to be in virtually publishable condition before they are first submitted,’ he said.

Do author-suggested reviewers rate submissions more favorably than editor-suggested reviewers? A study on atmospheric chemistry and physics.

PubMed

Bornmann, Lutz; Daniel, Hans-Dieter

2010-10-14

Ratings in journal peer review can be affected by sources of bias. The bias variable investigated here was the information on whether authors had suggested a possible reviewer for their manuscript, and whether the editor had taken up that suggestion or had chosen a reviewer that had not been suggested by the authors. Studies have shown that author-suggested reviewers rate manuscripts more favorably than editor-suggested reviewers do. Reviewers' ratings on three evaluation criteria and the reviewers' final publication recommendations were available for 552 manuscripts (in total 1145 reviews) that were submitted to Atmospheric Chemistry and Physics, an interactive open access journal using public peer review (authors' and reviewers' comments are publicly exchanged). Public peer review is supposed to bring a new openness to the reviewing process that will enhance its objectivity. In the statistical analysis the quality of a manuscript was controlled for to prevent favorable reviewers' ratings from being attributable to quality instead of to the bias variable. Our results agree with those from other studies that editor-suggested reviewers rated manuscripts between 30% and 42% less favorably than author-suggested reviewers. Against this backdrop journal editors should consider either doing without the use of author-suggested reviewers or, if they are used, bringing in more than one editor-suggested reviewer for the review process (so that the review by author-suggested reviewers can be put in perspective).

The First Pan-Starrs Medium Deep Field Variable Star Catalog

NASA Astrophysics Data System (ADS)

Flewelling, Heather

2013-01-01

We present the first Pan-Starrs 1 Medium Deep Field Variable Star Catalog (PS1-MDF-VSC). The Pan-Starrs 1 (PS1) telescope is a 1.8 meter survey telescope with a 1.4 Gigapixel camera, and is located in Haleakala, Hawaii. The Medium Deep survey, which consists of 10 fields located uniformly across the sky, totalling 70 square degrees, is observed each night, in 2-3 filters per field, with 8 exposures per filter. We have located and classified several hundred periodic variable stars within the Medium Deep fields, and we present the first catalog listing the properties of these variable stars.

Decadal change in PAN & O3 and their precursors levels in Seoul during May and June

NASA Astrophysics Data System (ADS)

Kim, H.; Rhee, H.; Lee, M.; Lee, G.; Jang, J.; Shin, H. J.

2017-12-01

In Seoul, PAN and O3 concentrations were examined for the two months of May and June, when O3 concentration is the highest of the year. The measurement sets of PAN and O3 are available for 2004, 2005, 2015 and 2016. PAN was measured by a fast GC system coupled with Luminol chemiluminescence. The hourly maximum PAN and O3 concentrations were10 ppbv and 123 ppbv in 2004,8 ppbv and 141 ppbv in 2005, 4.4 ppbv and 143 ppbv in 2015, and 7.5 ppbv and 127 ppbv in 2016, respectively. The total concentrations of NOX and VOCs were evidently decreased but with different proportions in their subclasses. While alkans and aromatics were considerably decreased, biogenic VOC(BVOC) were increased about twice, leading to increased contribution of BVOC to OH reactivity. Although NOX was decreased by 35%, NO2/NOX ratio was increased for the decade. PAN levels were decreased over the years corresponding to decrease in precursor levels. However, the concentration of O3 was increased due to an increase in NO2 / NO ratio and BVOC.

Mineralogy and geochemistry of the sediments of the Etosha Pan Region in northern Namibia: a reconstruction of the depositional environment

NASA Astrophysics Data System (ADS)

Buch, M. W.; Rose, D.

1996-04-01

The paper presents the results of mineralogical and chemical analyses of the clay fraction (<2 μm) of samples from boreholes in the Etosha Pan and smaller pans of the Owambo-Pans-Plain in the Etosha National Park, northern Namibia. Four mineral associations can be differentiated within the vertical succession of the profiles in the Etosha Pan: I) analcime/K-feldspar and mica association; II) analcime/K-feldspar and sepiolite (loughlinite) association; III) expandable sheet silicate (saponite/stevensite) association; and IV) calcite and dolomite association. These mineral associations are the expression of the seasonal saline-alkaline to calciferous, saline-alkaline environment of the present Etosha Pan. The sedimentological and pedological descriptions, combined with the results of the mineralogical and chemical analyses, show a clear differentiation of the profiles of the Etosha Pan in: i) disintegrated sedimentary rocks of the Andoni Formation (mineral association I); ii) par-autochthonous sediments (mineral associations I and II); and iii) allochthonous sediments (mineral associations III and IV). Based on this vertical mineralogical differentiation, four sedimentological-mineralogical/ chemical zones are defined for the actual floor of the Etosha Pan. The zonation shows that a thin cover of allochthonous sediments is only present along the southern margin of the Etosha Pan, including Fisher's Pan. The results support the hypothesis that the Etosha Pan is an erosional form rather than a palaeolake. In principle, the zonal configuration of the recent allochthonous and parautochthonous sediments identified on the Etosha Pan provides a small-scale depositional environment model for the formation of the Etosha limestone and sediments of the Andoni Formation during the Oligocene and Miocene. Thus, the findings help to reconstruct the depositional environment of the evolution of the extensive depocentre of the Etosha basin during the Late Tertiary.

Pan Sharpening Quality Investigation of Turkish In-Operation Remote Sensing Satellites: Applications with Rasat and GÖKTÜRK-2 Images

NASA Astrophysics Data System (ADS)

Ozendi, Mustafa; Topan, Hüseyin; Cam, Ali; Bayık, Çağlar

2016-10-01

Recently two optical remote sensing satellites, RASAT and GÖKTÜRK-2, launched successfully by the Republic of Turkey. RASAT has 7.5 m panchromatic, and 15 m visible bands whereas GÖKTÜRK-2 has 2.5 m panchromatic and 5 m VNIR (Visible and Near Infrared) bands. These bands with various resolutions can be fused by pan-sharpening methods which is an important application area of optical remote sensing imagery. So that, the high geometric resolution of panchromatic band and the high spectral resolution of VNIR bands can be merged. In the literature there are many pan-sharpening methods. However, there is not a standard framework for quality investigation of pan-sharpened imagery. The aim of this study is to investigate pan-sharpening performance of RASAT and GÖKTÜRK-2 images. For this purpose, pan-sharpened images are generated using most popular pan-sharpening methods IHS, Brovey and PCA at first. This procedure is followed by quantitative evaluation of pan-sharpened images using Correlation Coefficient (CC), Root Mean Square Error (RMSE), Relative Average Spectral Error (RASE), Spectral Angle Mapper (SAM) and Erreur Relative Globale Adimensionnelle de Synthése (ERGAS) metrics. For generation of pan-sharpened images and computation of metrics SharpQ tool is used which is developed with MATLAB computing language. According to metrics, PCA derived pan-sharpened image is the most similar one to multispectral image for RASAT, and Brovey derived pan-sharpened image is the most similar one to multispectral image for GÖKTÜRK-2. Finally, pan-sharpened images are evaluated qualitatively in terms of object availability and completeness for various land covers (such as urban, forest and flat areas) by a group of operators who are experienced in remote sensing imagery.

Gravity and solidity in four great ape species (Gorilla gorilla, Pongo pygmaeus, Pan troglodytes, Pan paniscus): vertical and horizontal variations of the table task.

PubMed

Cacchione, Trix; Call, Josep; Zingg, Robert

2009-05-01

Three experiments modeled after infant studies were run on four great ape species (Gorilla gorilla, Pongo pygmaeus, Pan troglodytes, Pan paniscus) to investigate their reasoning about solidity and gravity constraints. The aims were: (a) to find out if great apes are subject to gravity biased search or display sensitivity for object solidity, (b) to check for species differences, and (c) to assess if a gravity hypothesis or more parsimonious explanations best account for failures observed. Results indicate that great apes, unlike monkeys, show no reliable gravity bias, that ape species slightly differ in terms of their performance, and that the errors made are best explained by a gravity account. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

The Pan 13th Annual Forum

DTIC Science & Technology

2007-11-01

NOTES 14. ABSTRACT This conference grant supported the Parkinson’s Action Network (PAN)’s 13th Annual Research and Education Forum for...community. PAN’s Research and Education Forum serves as a premier educational program for Parkinson’s physicians, patients, researchers as well...participants will learn about the latest research and discuss creative ideas for new research endeavors. Fundamental to the success of the Forum is the premise

Improving the Yield of Rural Education Research: An Editor's Swan Song

ERIC Educational Resources Information Center

Coladarci, Theodore

2007-01-01

In my 15th and final year as JRRE editor, I identify methodological and substantive shortcomings in the rural education research literature and, in turn, suggest strategies for improvement. I structure my observations around the following considerations: describing the rural context of research, making the rural argument, framing the research…

Shape of the piriform aperture in Gorilla gorilla, Pan troglodytes, and modern Homo sapiens: characterization and polymorphism analysis.

PubMed

Schmittbuhl, M; Le Minor, J M; Allenbach, B; Schaaf, A

1998-07-01

By using new methodologies based on automatic image analysis, the shape of the piriform aperture was analyzed in Gorilla gorilla (33 males, 13 females), Pan troglodytes (35 males, 22 females), and modern Homo sapiens (30 males, 12 females). The determination of the piriform aperture index (breadth/height) allowed the authors to demonstrate a marked elongation of the aperture in Homo compared with Gorilla and Pan. Individual characterization of the shape was possible with great precision and without ambiguity by using Fourier analysis. An absolute, interspecific partition between Gorilla, Pan, and Homo resulted from the canonical discriminant analysis of the Fourier descriptors. However, a closeness of shape between some individuals in Pan and some in Gorilla and Homo was observed, demonstrating a morphological continuum of the shape of the piriform aperture in hominoids: Pan was in intermediate position between Gorilla and Homo. Interspecific differences between Homo and the group Pan-Gorilla were explained principally by the differences in elongation (amplitude of the second harmonic) and pentagonality (amplitude of the fifth harmonic) and by differences in orientation of quadrangularity (phase of the fourth harmonic). Differences in the shape of the piriform aperture between Pan and Gorilla were explained by differences in orientation of elongation (phase of the second harmonic) and by differences in the component of triangularity (amplitude of the third harmonic). In Gorilla and Pan, the little, elongated, and relatively trapezoidal piriform aperture seems to be a shared primitive feature (plesiomorphic), whereas an elongated piriform aperture seems to be a characteristic and derived feature (apomorphic) of modern Homo sapiens.

Evaluation of common methods for sampling invertebrate pollinator assemblages: net sampling out-perform pan traps.

PubMed

Popic, Tony J; Davila, Yvonne C; Wardle, Glenda M

2013-01-01

Methods for sampling ecological assemblages strive to be efficient, repeatable, and representative. Unknowingly, common methods may be limited in terms of revealing species function and so of less value for comparative studies. The global decline in pollination services has stimulated surveys of flower-visiting invertebrates, using pan traps and net sampling. We explore the relative merits of these two methods in terms of species discovery, quantifying abundance, function, and composition, and responses of species to changing floral resources. Using a spatially-nested design we sampled across a 5000 km(2) area of arid grasslands, including 432 hours of net sampling and 1296 pan trap-days, between June 2010 and July 2011. Net sampling yielded 22% more species and 30% higher abundance than pan traps, and better reflected the spatio-temporal variation of floral resources. Species composition differed significantly between methods; from 436 total species, 25% were sampled by both methods, 50% only by nets, and the remaining 25% only by pans. Apart from being less comprehensive, if pan traps do not sample flower-visitors, the link to pollination is questionable. By contrast, net sampling functionally linked species to pollination through behavioural observations of flower-visitation interaction frequency. Netted specimens are also necessary for evidence of pollen transport. Benefits of net-based sampling outweighed minor differences in overall sampling effort. As pan traps and net sampling methods are not equivalent for sampling invertebrate-flower interactions, we recommend net sampling of invertebrate pollinator assemblages, especially if datasets are intended to document declines in pollination and guide measures to retain this important ecosystem service.

gLExec and MyProxy integration in the ATLAS/OSG PanDA workload management system

NASA Astrophysics Data System (ADS)

Caballero, J.; Hover, J.; Litmaath, M.; Maeno, T.; Nilsson, P.; Potekhin, M.; Wenaus, T.; Zhao, X.

2010-04-01

Worker nodes on the grid exhibit great diversity, making it difficult to offer uniform processing resources. A pilot job architecture, which probes the environment on the remote worker node before pulling down a payload job, can help. Pilot jobs become smart wrappers, preparing an appropriate environment for job execution and providing logging and monitoring capabilities. PanDA (Production and Distributed Analysis), an ATLAS and OSG workload management system, follows this design. However, in the simplest (and most efficient) pilot submission approach of identical pilots carrying the same identifying grid proxy, end-user accounting by the site can only be done with application-level information (PanDA maintains its own end-user accounting), and end-user jobs run with the identity and privileges of the proxy carried by the pilots, which may be seen as a security risk. To address these issues, we have enabled PanDA to use gLExec, a tool provided by EGEE which runs payload jobs under an end-user's identity. End-user proxies are pre-staged in a credential caching service, MyProxy, and the information needed by the pilots to access them is stored in the PanDA DB. gLExec then extracts from the user's proxy the proper identity under which to run. We describe the deployment, installation, and configuration of gLExec, and how PanDA components have been augmented to use it. We describe how difficulties were overcome, and how security risks have been mitigated. Results are presented from OSG and EGEE Grid environments performing ATLAS analysis using PanDA and gLExec.

Evaluation of Common Methods for Sampling Invertebrate Pollinator Assemblages: Net Sampling Out-Perform Pan Traps

PubMed Central

Popic, Tony J.; Davila, Yvonne C.; Wardle, Glenda M.

2013-01-01

Methods for sampling ecological assemblages strive to be efficient, repeatable, and representative. Unknowingly, common methods may be limited in terms of revealing species function and so of less value for comparative studies. The global decline in pollination services has stimulated surveys of flower-visiting invertebrates, using pan traps and net sampling. We explore the relative merits of these two methods in terms of species discovery, quantifying abundance, function, and composition, and responses of species to changing floral resources. Using a spatially-nested design we sampled across a 5000 km2 area of arid grasslands, including 432 hours of net sampling and 1296 pan trap-days, between June 2010 and July 2011. Net sampling yielded 22% more species and 30% higher abundance than pan traps, and better reflected the spatio-temporal variation of floral resources. Species composition differed significantly between methods; from 436 total species, 25% were sampled by both methods, 50% only by nets, and the remaining 25% only by pans. Apart from being less comprehensive, if pan traps do not sample flower-visitors, the link to pollination is questionable. By contrast, net sampling functionally linked species to pollination through behavioural observations of flower-visitation interaction frequency. Netted specimens are also necessary for evidence of pollen transport. Benefits of net-based sampling outweighed minor differences in overall sampling effort. As pan traps and net sampling methods are not equivalent for sampling invertebrate-flower interactions, we recommend net sampling of invertebrate pollinator assemblages, especially if datasets are intended to document declines in pollination and guide measures to retain this important ecosystem service. PMID:23799127

The complete mitochondrial genome of the central chimpanzee, Pan troglodytes troglodytes.

PubMed

Liu, Bang; Hu, Xiao-di; Gao, Li-Zhi

2016-07-01

This study first report the complete mitochondrial genome sequence of the central chimpanzee, Pan troglodytes troglodytes. The genome was a total of 16 556 bp in length and had a base composition of A (31.05%), G (12.95%), C (30.84%), and T (25.16%), indicating that the percentage of A + T (56.21%) is higher than G + C (43.79%). Similar to other primates, it possessed a typically conserved structure, including 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes and 1 control region (D-loop). Most of these genes were found to locate on the H-strand except for the ND6 gene and 8 tRNA genes. The phylogenetic analysis showed that the P. t. troglodytes mitochondrial genome formed a cluster with the other three Pan troglodytes genomes and that the genus Pan is closely related to the genus Homo. This mitochondrial genome sequence would supply useful genetic resources to help the conservation management of primate germplasm and uncover hominoid evolution.

Localization and regulation of mouse pantothenate kinase 2 [The PanK2 Genes of Mouse and Human Specify Proteins with Distinct Subcellular Locations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leonardi, Roberta; Zhang, Yong-Mei; Lykidis, Athanasios

2007-09-07

Coenzyme A (CoA) biosynthesis is initiated by pantothenatekinase (PanK) and CoA levels are controlled through differentialexpression and feedback regulation of PanK isoforms. PanK2 is amitochondrial protein in humans, but comparative genomics revealed thatacquisition of a mitochondrial targeting signal was limited to primates.Human and mouse PanK2 possessed similar biochemical properties, withinhibition by acetylCoA and activation by palmitoylcarnitine. Mouse PanK2localized in the cytosol, and the expression of PanK2 was higher in humanbrain compared to mouse brain. Differences in expression and subcellularlocalization should be considered in developing a mouse model for humanPanK2 deficiency.

Effect of Buttermilk on the Physicochemical, Rheological, and Sensory Qualities of Pan and Pita Bread

PubMed Central

2017-01-01

The aim of this study was to evaluate the influence of buttermilk on the physicochemical and sensory attributes of pan and pita breads. Different amounts of buttermilk (30, 60, and 100% of added water) were mixed with other ingredients of pan and pita bread formulations. The doughs and bread were analyzed for rheological, physicochemical, and sensory qualities. The results demonstrated that incorporation of different concentrations of buttermilk in bread formulations progressively enhanced water absorption capacity, dough development time, gelatinization temperature, and peak viscosity, whereas it reduced the dough stability and temperature at peak viscosity. Supplementation of wheat flour with 30% buttermilk significantly (P ≤ 0.05) enhanced the physical properties of pan bread compared to nonsupplemented control. Incorporation of different percentages of buttermilk in bread formulation concomitantly (P ≤ 0.05) increased protein, oil, and ash contents and it reduced the carbohydrate contents of both types of bread. Incorporation of 60 and 100% of buttermilk in bread formula showed low scores of all sensory attributes compared to control and 30% buttermilk containing pan and pita bread. In conclusion, supplementation of bread formulas with 30% buttermilk is recommended for improving the nutritional and sensorial qualities of pan and pita bread. PMID:29318139

PanFP: Pangenome-based functional profiles for microbial communities

DOE PAGES

Jun, Se -Ran; Hauser, Loren John; Schadt, Christopher Warren; ...

2015-09-26

For decades there has been increasing interest in understanding the relationships between microbial communities and ecosystem functions. Current DNA sequencing technologies allows for the exploration of microbial communities in two principle ways: targeted rRNA gene surveys and shotgun metagenomics. For large study designs, it is often still prohibitively expensive to sequence metagenomes at both the breadth and depth necessary to statistically capture the true functional diversity of a community. Although rRNA gene surveys provide no direct evidence of function, they do provide a reasonable estimation of microbial diversity, while being a very cost effective way to screen samples of interestmore » for later shotgun metagenomic analyses. However, there is a great deal of 16S rRNA gene survey data currently available from diverse environments, and thus a need for tools to infer functional composition of environmental samples based on 16S rRNA gene survey data. As a result, we present a computational method called pangenome based functional profiles (PanFP), which infers functional profiles of microbial communities from 16S rRNA gene survey data for Bacteria and Archaea. PanFP is based on pangenome reconstruction of a 16S rRNA gene operational taxonomic unit (OTU) from known genes and genomes pooled from the OTU s taxonomic lineage. From this lineage, we derive an OTU functional profile by weighting a pangenome s functional profile with the OTUs abundance observed in a given sample. We validated our method by comparing PanFP to the functional profiles obtained from the direct shotgun metagenomic measurement of 65 diverse communities via Spearman correlation coefficients. These correlations improved with increasing sequencing depth, within the range of 0.8 0.9 for the most deeply sequenced Human Microbiome Project mock community samples. PanFP is very similar in performance to another recently released tool, PICRUSt, for almost all of survey data analysed here. But

PanDaTox: A tool for accelerated metabolic engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amitai, Gil; Sorek, Rotem

2012-07-18

Metabolic engineering is often facilitated by cloning of genes encoding enzymes from various heterologous organisms into E. coli. Such engineering efforts are frequently hampered by foreign genes that are toxic to the E. coli host. We have developed PanDaTox (www.weizmann.ac.il/pandatox), a web-based resource that provides experimental toxicity information for more than 1.5 million genes from hundreds of different microbial genomes. The toxicity predictions, which were extensively experimentally verified, are based on serial cloning of genes into E. coli as part of the Sanger whole genome shotgun sequencing process. PanDaTox can accelerate metabolic engineering projects by allowing researchers to exclude toxicmore » genes from the engineering plan and verify the clonability of selected genes before the actual metabolic engineering experiments are conducted.« less

The effects of an editor serving as one of the reviewers during the peer-review process.

PubMed

Giordan, Marco; Csikasz-Nagy, Attila; Collings, Andrew M; Vaggi, Federico

2016-01-01

Background Publishing in scientific journals is one of the most important ways in which scientists disseminate research to their peers and to the wider public. Pre-publication peer review underpins this process, but peer review is subject to various criticisms and is under pressure from growth in the number of scientific publications. Methods Here we examine an element of the editorial process at eLife , in which the Reviewing Editor usually serves as one of the referees, to see what effect this has on decision times, decision type, and the number of citations. We analysed a dataset of 8,905 research submissions to eLife since June 2012, of which 2,747 were sent for peer review. This subset of 2747 papers was then analysed in detail.   Results The Reviewing Editor serving as one of the peer reviewers results in faster decision times on average, with the time to final decision ten days faster for accepted submissions (n=1,405) and five days faster for papers that were rejected after peer review (n=1,099). Moreover, editors acting as reviewers had no effect on whether submissions were accepted or rejected, and a very small (but significant) effect on citation rates. Conclusions An important aspect of eLife 's peer-review process is shown to be effective, given that decision times are faster when the Reviewing Editor serves as a reviewer. Other journals hoping to improve decision times could consider adopting a similar approach.

Pan-Continental Droughts in North America over the Last Millennium

NASA Technical Reports Server (NTRS)

Cook, Benjamin I.; Smerdon, Jason E.; Seager, Richard; Cook, Edward R.

2014-01-01

Regional droughts are common in North America, but pan-continental droughts extending across multiple regions, including the 2012 event, are rare relative to single-region events. Here, the tree-ring-derived North American Drought Atlas is used to investigate drought variability in four regions over the last millennium, focusing on pan-continental droughts. During the Medieval Climate Anomaly (MCA), the central plains (CP), Southwest (SW), and Southeast (SE) regions experienced drier conditions and increased occurrence of droughts and the Northwest (NW) experienced several extended pluvials. Enhanced MCA aridity in the SW and CP manifested as multidecadal megadroughts. Notably, megadroughts in these regions differed in their timing and persistence, suggesting that they represent regional events influenced by local dynamics rather than a unified, continental-scale phenomena. There is no trend in pan-continental drought occurrence, defined as synchronous droughts in three or more regions. SW, CP, and SE (SW+CP+SE) droughts are the most common, occurring in 12 percent of all years and peaking in prevalence during the twelfth and thirteenth centuries; patterns involving three other regions occur in about 8 percent of years. Positive values of the Southern Oscillation index (La Nina conditions) are linked to SW, CP, and SE (SW+CP+SE) droughts and SW, CP, and NW (SW+CP+NW) droughts, whereas CP, NW, and SE (CP+NW+SE) droughts are associated with positive values of the Pacific decadal oscillation and Atlantic multidecadal oscillation. While relatively rare, pan-continental droughts are present in the paleo record and are linked to defined modes of climate variability, implying the potential for seasonal predictability. Assuming stable drought teleconnections, these events will remain an important feature of future North American hydroclimate, possibly increasing in their severity in step with other expected hydroclimate responses to increased greenhouse gas forcing.

A survey of the awareness, knowledge, policies and views of veterinary journal Editors-in-Chief on reporting guidelines for publication of research

PubMed Central

2014-01-01

Background Wider adoption of reporting guidelines by veterinary journals could improve the quality of published veterinary research. The aims of this study were to assess the knowledge and views of veterinary Editors-in-Chief on reporting guidelines, identify the policies of their journals, and determine their information needs. Editors-in-Chief of 185 journals on the contact list for the International Association of Veterinary Editors (IAVE) were surveyed in April 2012 using an online questionnaire which contained both closed and open questions. Results The response rate was 36.8% (68/185). Thirty-six of 68 editors (52.9%) stated they knew what a reporting guideline was before receiving the questionnaire. Editors said they had found out about reporting guidelines primarily through articles in other journals, via the Internet and through their own journal. Twenty of 57 respondents (35.1%) said their journal referred to reporting guidelines in its instructions to authors. CONSORT, REFLECT, and ARRIVE were the most frequently cited. Forty-four of 68 respondents (68.2%) believed that reporting guidelines should be adopted by all refereed veterinary journals. Qualitative analysis of the open questions revealed that lack of knowledge, fear, resistance to change, and difficulty in implementation were perceived as barriers to the adoption of reporting guidelines by journals. Editors suggested that reporting guidelines be promoted through communication and education of the veterinary community, with roles for the IAVE and universities. Many respondents believed a consensus policy on guideline implementation was needed for veterinary journals. Conclusions Further communication and education about reporting guidelines for editors, authors and reviewers has the potential to increase their adoption by veterinary journals in the future. PMID:24410882

Programming the Navier-Stokes computer: An abstract machine model and a visual editor

NASA Technical Reports Server (NTRS)

Middleton, David; Crockett, Tom; Tomboulian, Sherry

1988-01-01

The Navier-Stokes computer is a parallel computer designed to solve Computational Fluid Dynamics problems. Each processor contains several floating point units which can be configured under program control to implement a vector pipeline with several inputs and outputs. Since the development of an effective compiler for this computer appears to be very difficult, machine level programming seems necessary and support tools for this process have been studied. These support tools are organized into a graphical program editor. A programming process is described by which appropriate computations may be efficiently implemented on the Navier-Stokes computer. The graphical editor would support this programming process, verifying various programmer choices for correctness and deducing values such as pipeline delays and network configurations. Step by step details are provided and demonstrated with two example programs.

Pan-London tuberculosis services: a service evaluation

PubMed Central

2012-01-01

Background London has the largest proportion of tuberculosis (TB) cases of any western European capital, with almost half of new cases drug-resistant. Prevalence varies considerably between and within boroughs with research suggesting inadequate control of TB transmission in London. Economic pressures may exacerbate the already considerable challenges for service organisation and delivery within this context. This paper presents selected findings from an evaluation of London’s TB services’ organisation, delivery, professional workforce and skill mix, intended to support development of a strategic framework for a pan-London TB service. These may also interest health service professionals and managers in TB services in the UK, other European cities and countries and in services currently delivered by multiple providers operating independently. Methods Objectives were: 1) To establish how London’s TB services are structured and delivered in relation to leadership, management, organisation and delivery, coordination, staffing and support; 2) To identify tools/models for calculating skill mix as a basis for identifying skill mix requirements in delivering TB services across London; 3) To inform a strategic framework for the delivery of a pan-London TB service, which may be applicable to other European cities. The multi-method service audit evaluation comprised documentary analysis, semi-structured interviews with TB service users (n = 10), lead TB health professionals and managers (n = 13) representing London’s five sectors and focus groups with TB nurses (n = 8) and non-London network professionals (n = 2). Results Findings showed TB services to be mainly hospital-based, with fewer community-based services. Documentary analysis and professionals’ interviews suggested difficulties with early access to services, low suspicion index amongst some GPs and restricted referral routes. Interviews indicated lack of managed accommodation for

Do Author-Suggested Reviewers Rate Submissions More Favorably than Editor-Suggested Reviewers? A Study on Atmospheric Chemistry and Physics

PubMed Central

Bornmann, Lutz; Daniel, Hans-Dieter

2010-01-01

Background Ratings in journal peer review can be affected by sources of bias. The bias variable investigated here was the information on whether authors had suggested a possible reviewer for their manuscript, and whether the editor had taken up that suggestion or had chosen a reviewer that had not been suggested by the authors. Studies have shown that author-suggested reviewers rate manuscripts more favorably than editor-suggested reviewers do. Methodology/Principal Findings Reviewers' ratings on three evaluation criteria and the reviewers' final publication recommendations were available for 552 manuscripts (in total 1145 reviews) that were submitted to Atmospheric Chemistry and Physics, an interactive open access journal using public peer review (authors' and reviewers' comments are publicly exchanged). Public peer review is supposed to bring a new openness to the reviewing process that will enhance its objectivity. In the statistical analysis the quality of a manuscript was controlled for to prevent favorable reviewers' ratings from being attributable to quality instead of to the bias variable. Conclusions/Significance Our results agree with those from other studies that editor-suggested reviewers rated manuscripts between 30% and 42% less favorably than author-suggested reviewers. Against this backdrop journal editors should consider either doing without the use of author-suggested reviewers or, if they are used, bringing in more than one editor-suggested reviewer for the review process (so that the review by author-suggested reviewers can be put in perspective). PMID:20976226

Integration Of PanDA Workload Management System With Supercomputers for ATLAS and Data Intensive Science

NASA Astrophysics Data System (ADS)

Klimentov, A.; De, K.; Jha, S.; Maeno, T.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Wells, J.; Wenaus, T.

2016-10-01

The.LHC, operating at CERN, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250,000 cores with a peak performance of 0.3 petaFLOPS, LHC data taking runs require more resources than grid can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility. Current approach utilizes modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on LCFs multi-core worker nodes. This implementation was tested with a variety of Monte-Carlo workloads on several supercomputing platforms for ALICE and ATLAS experiments and it is in full pro duction for the ATLAS since September 2015. We will present our current accomplishments with running PanDA at supercomputers and demonstrate our ability to use PanDA as a portal independent of the

GigaPan Technology to Enhance In-Class and In-Field Learning in Community College Settings

NASA Astrophysics Data System (ADS)

Villalobos, J. I.; Bentley, C.

2014-12-01

Community college students account for over 40% of all undergraduates in the United States as well as the majority of minority and non-traditional students attending undergraduate courses. Implementing innovative, cost effective, and formative pedagogies to the diverse backgrounds of students that typically enroll at a community is often a challenge. Interactive pedagogies in geology pose a unique challenge considering that students gain the most long-term knowledge when topics covered in a course are exposed to them in outdoor settings where they are allowed to explore and make connections. The ability to expose students to real world examples is challenging to many community college faculty considering that that many; lack funds or means for transportation of students, do not have administrative support on such endeavors, teach evening or night classes, or have a high percentage of students who are physically limited or have obligations to work and family. A joint collaborative between El Paso Community College (EPCC) and Northern Virginia Community College (NOVA) has explored the usage of GigaPan technology to create multi-layered online material to minimize these issues faced by many community college faculty and students. The primary layer of the online material is GigaPans of local geological sites that highlight large-scale structures in the El Paso, Texas region that are commonly used in local field trips and lab book material. The second layer is of Macro-GigaPans of hand samples of key outcrops from the primarily GigaPans which facilitate student learning, exploration, and ability to make connections by exploring smaller scale features of the primary layer. A third layer of online material, GigaPans of thin sections of hand samples (from secondary layers), and curriculum based on the GigaPans was then created to assist students in evaluating proposed hypotheses on the primary layers' geological origin. GigaPan cirriculum was utilized in introductory

NGSPanPipe: A Pipeline for Pan-genome Identification in Microbial Strains from Experimental Reads.

PubMed

Kulsum, Umay; Kapil, Arti; Singh, Harpreet; Kaur, Punit

2018-01-01

Recent advancements in sequencing technologies have decreased both time span and cost for sequencing the whole bacterial genome. High-throughput Next-Generation Sequencing (NGS) technology has led to the generation of enormous data concerning microbial populations publically available across various repositories. As a consequence, it has become possible to study and compare the genomes of different bacterial strains within a species or genus in terms of evolution, ecology and diversity. Studying the pan-genome provides insights into deciphering microevolution, global composition and diversity in virulence and pathogenesis of a species. It can also assist in identifying drug targets and proposing vaccine candidates. The effective analysis of these large genome datasets necessitates the development of robust tools. Current methods to develop pan-genome do not support direct input of raw reads from the sequencer machine but require preprocessing of reads as an assembled protein/gene sequence file or the binary matrix of orthologous genes/proteins. We have designed an easy-to-use integrated pipeline, NGSPanPipe, which can directly identify the pan-genome from short reads. The output from the pipeline is compatible with other pan-genome analysis tools. We evaluated our pipeline with other methods for developing pan-genome, i.e. reference-based assembly and de novo assembly using simulated reads of Mycobacterium tuberculosis. The single script pipeline (pipeline.pl) is applicable for all bacterial strains. It integrates multiple in-house Perl scripts and is freely accessible from https://github.com/Biomedinformatics/NGSPanPipe .

Endocranial shape asymmetries in Pan paniscus, Pan troglodytes and Gorilla gorilla assessed via skull based landmark analysis.

PubMed

Balzeau, Antoine; Gilissen, Emmanuel

2010-07-01

Brain shape asymmetries or petalias consist of the extension of one cerebral hemisphere beyond the other. A larger frontal or caudal projection is usually coupled with a larger lateral extent of the more projecting hemisphere relative to the other. The concurrence of these petalial components is characteristic of hominins. Studies aimed at quantifying petalial asymmetries in human and great ape endocasts rely on the definition of the midline of the endocranial surface. Studies of brain material show that, at least in humans, most of the medial surface of the left occipital lobe distorts along the midline and protrudes on to the right side, making it difficult for midline and corresponding left and right reference point identification. In order to accurately quantify and compare brain shape asymmetries in extant hominid species, we propose here a new protocol based on the objective definition of cranial landmarks. We describe and quantify for the first time in three dimensions the positions of frontal and occipital protrusions in large samples of Pan paniscus, Pan troglodytes and Gorilla gorilla. This study confirms the existence of frontal and occipital petalias in African apes. Moreover, the detailed analysis of the 3D structure of these petalias reveals shared features, as well as features that are unique to the different great ape species.

Charge Diffusion Variations in Pan-STARRS1 CCDs

NASA Astrophysics Data System (ADS)

Magnier, Eugene A.; Tonry, J. L.; Finkbeiner, D.; Schlafly, E.; Burgett, W. S.; Chambers, K. C.; Flewelling, H. A.; Hodapp, K. W.; Kaiser, N.; Kudritzki, R.-P.; Metcalfe, N.; Wainscoat, R. J.; Waters, C. Z.

2018-06-01

Thick back-illuminated deep-depletion CCDs have superior quantum efficiency over previous generations of thinned and traditional thick CCDs. As a result, they are being used for wide-field imaging cameras in several major projects. We use observations from the Pan-STARRS 3π survey to characterize the behavior of the deep-depletion devices used in the Pan-STARRS 1 Gigapixel Camera. We have identified systematic spatial variations in the photometric measurements and stellar profiles that are similar in pattern to the so-called “tree rings” identified in devices used by other wide-field cameras (e.g., DECam and Hypersuprime Camera). The tree-ring features identified in these other cameras result from lateral electric fields that displace the electrons as they are transported in the silicon to the pixel location. In contrast, we show that the photometric and morphological modifications observed in the GPC1 detectors are caused by variations in the vertical charge transportation rate and resulting charge diffusion variations.

Millisecond Pulsar Companions in SDSS and Pan-Starrs

NASA Astrophysics Data System (ADS)

McMann, Natasha; Holley-Bockelmann, Kelly; McLaughlin, Maura; Kaplan, David; NANOGrav

2018-01-01

Millisecond pulsars (MSPs) are being timed precisely in hopes of detecting gravitational waves (GWs). In order to detect GWs, pulsars must be studied in great detail. The perturbations in timing caused by binaries must be determined so as not to confuse them with a GW perturbation. This study used a list of published MSPs to determine if any known MSP’s white dwarf companions are located and visible in the Sloan Digital Sky Survey (SDSS) and the Panoramic Survey Telescope and Rapid Response System (Pan-Starrs) Footprints. No new possible companions were discovered but five objects were found in the SDSS and 18, including the same five from SDSS, were found in Pan-Starrs that could be the companion to an MSP. All objects are less than 1.5 arcseconds away from the MSP’s position. In order to verify the object as the companion, the color magnitudes must be compared to those previously published.

2012 Special NSREC Issue of the IEEE Transactions on Nuclear Science Comments by the Editors

NASA Astrophysics Data System (ADS)

Schwank, Jim; Brown, Dennis; Girard, Sylvain; Gouker, Pascale; Gerardin, Simone; Quinn, Heather; Barnaby, Hugh

2012-12-01

The December 2012 special issue of the IEEE Transactions on Nuclear Science contains selected papers from the 49th annual IEEE International Nuclear and Space Radiation Effects Conference (NSREC) held July 16-20, 2012, in Miami, Florida USA. 95 papers presented at the 2012 NSREC were submitted for consideration for this year’s special issue. Those papers that appear in this special issue were able to successfully complete the review process before the deadline for the December issue. A few additional papers may appear in subsequent issues of the TRANSACTIONS. This publication is the premier archival journal for research on space and nuclear radiation effects in materials, devices, circuits, and systems. This distinction is the direct result of the conscientious efforts of both the authors, who present and document their work, and the reviewers, who selflessly volunteer their time and talent to help review the manuscripts. Each paper in this journal has been reviewed by experts selected by the editors for their expertise and knowledge of the particular subject areas. The peer review process for a typical technical journal generally takes six months to one year to complete. To publish this special issue of the IEEE Transactions on Nuclear Science (in December), the review process, from initial submission to final form, must be completed in about 10 weeks. Because of the short schedule, both the authors and reviewers are required to respond very quickly. The reviewers listed on the following pages contributed vitally to this quick-turn review process.We would like to express our sincere appreciation to each of them for accepting this difficult, but critical role in the process. To provide consistent reviews of papers throughout the year, the IEEE Transactions on Nuclear Science relies on a year-round editorial board that manages reviews for submissions throughout the year to the TRANSACTIONS in the area of radiation effects. The review process is managed by a Senior

40 CFR 428.90 - Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., dry digestion, and mechanical reclaimed rubber subcategory. 428.90 Section 428.90 Protection of... POINT SOURCE CATEGORY Pan, Dry Digestion, and Mechanical Reclaimed Rubber Subcategory § 428.90 Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory. The...

40 CFR 428.90 - Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., dry digestion, and mechanical reclaimed rubber subcategory. 428.90 Section 428.90 Protection of... POINT SOURCE CATEGORY Pan, Dry Digestion, and Mechanical Reclaimed Rubber Subcategory § 428.90 Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory. The...

Token transfers among great apes (Gorilla gorilla, Pongo pygmaeus, Pan paniscus, and Pan troglodytes): species differences, gestural requests, and reciprocal exchange.

PubMed

Pelé, Marie; Dufour, Valérie; Thierry, Bernard; Call, Josep

2009-11-01

Great apes appear to be the nonhuman primates most capable of recognizing trading opportunities and engaging in transfers of commodities with conspecifics. Spontaneous exchange of goods between them has not yet been reported. We tested gorillas (Gorilla gorilla), orangutans (Pongo pygmaeus), bonobos (Pan paniscus), and chimpanzees (Pan troglodytes) in a token-exchange task involving two conspecifics and a human experimenter. Tested in pairs, subjects had to exchange tokens with a partner to obtain food from the experimenter. We observed 4, 5, 264, and 328 transfers of tokens in gorillas, chimpanzees, orangutans, and bonobos, respectively. Most gifts were indirect in gorillas, chimpanzees, and bonobos, whereas most were direct in orangutans. The analysis showed no evidence of calculated reciprocity in interactions. A main finding of the study was the high rate of repeated gifts and begging gestures recorded in orangutans. This raises the question of the meaning of pointing in great apes and their ability to understand the communicative intent of others.

Assessing Toxicity of Obscurant Grade Pan-Based Carbon Fiber Aquatic Species Chronic Tests

DTIC Science & Technology

2004-12-01

ASSESSING TOXICITY OF OBSCURANT GRADE PAN-BASED CARBON FIBER: AQUATIC SPECIES CHRONIC TESTS N. A. Chester, M. V. Haley, C. W. Kurnas and R. T...with minimal restrictions. To this end we are investigating the toxicity of PAN-based carbon fibers to the aquatic species Ceriodaphnia dubia (water... toxicity methods to provide ecotoxicological results for both lethal and sub-lethal parameters, including LC50 (24-, 48- and 96-h), IC50, EC20, and

Foliar injury response of petunia and kidney bean to simultaneous and alternate exposures to ozone and pan

NASA Astrophysics Data System (ADS)

Nouchi, Isamu; Mayumi, Hirokazu; Yamazoe, Fumio

Petunia at about 6 weeks old and kidney bean at two growing stages (6-7 days old and 16-18 days old) were exposed separately to O 3, (0-0.40 ppm) and PAN (0-0.25 ppm) for 4 h and to the mixture for the same time. In addition, petunia was exposed to O, (0.10-0.40 ppm) and then PAN (0.010-0.040 ppm) for 4 h, respectively. Foliar injury of petunia and kidney bean in exposures to the mixtures of O 3 and PAN was significantly smaller than that induced by each oxidant, with the exception of PAN injury on young leaves of 16-18 day-old kidney bean. The percentage of foliar injury caused by either of the mixed pollutants decreased with an increase of the concentration of the other oxidant, and was found to approximate a logarithmic function of the combined pollutant concentrations expressed as O 3, minum PAN or vice versa. Alternate exposures caused no additive or synergistic injuries.

On the theory relating changes in area-average and pan evaporation (Invited)

NASA Astrophysics Data System (ADS)

Shuttleworth, W.; Serrat-Capdevila, A.; Roderick, M. L.; Scott, R.

2009-12-01

Theory relating changes in area-average evaporation with changes in the evaporation from pans or open water is developed. Such changes can arise by Type (a) processes related to large-scale changes in atmospheric concentrations and circulation that modify surface evaporation rates in the same direction, and Type (b) processes related to coupling between the surface and atmospheric boundary layer (ABL) at the landscape scale that usually modify area-average evaporation and pan evaporation in different directions. The interrelationship between evaporation rates in response to Type (a) changes is derived. They have the same sign and broadly similar magnitude but the change in area-average evaporation is modified by surface resistance. As an alternative to assuming the complementary evaporation hypothesis, the results of previous modeling studies that investigated surface-atmosphere coupling are parameterized and used to develop a theoretical description of Type (b) coupling via vapor pressure deficit (VPD) in the ABL. The interrelationship between appropriately normalized pan and area-average evaporation rates is shown to vary with temperature and wind speed but, on average, the Type (b) changes are approximately equal and opposite. Long-term Australian pan evaporation data are analyzed to demonstrate the simultaneous presence of Type (a) and (b) processes, and observations from three field sites in southwestern USA show support for the theory describing Type (b) coupling via VPD. England's victory over Australia in 2009 Ashes cricket test match series will not be mentioned.

Editor in Chief[R] Beginning: Grammar Disasters and Punctuation Faux Pas.

ERIC Educational Resources Information Center

Beckwith, Carrie; Block, Cheryl; Broz, Christine; Hockett, Margaret; White, David

This workbook is designed as an introduction to the "Editor in Chief" series, which reinforces the rules of written English. In this workbook, student first review the rules of grammar and mechanics using multiple-choice questions; then the students learn to apply these rules in context by editing stories in a variety of formats. This "Beginning"…

A profile of Fritiof S. Sjöstrand--the founding editor.

PubMed

Maunsbach, Arvid B

2008-09-01

The Journal of Ultrastructure Research was founded in 1957 by Fritiof S. Sjöstrand, who served as Editor-in-Chief until 1990, when the journal changed the name to the Journal of Structural Biology. This profile summarizes the developments that led to the start of the journal and aspects of Fritiof Sjöstrand's scientific and personal carrier.

Artificial intelligence in peer review: How can evolutionary computation support journal editors?

PubMed

Mrowinski, Maciej J; Fronczak, Piotr; Fronczak, Agata; Ausloos, Marcel; Nedic, Olgica

2017-01-01

With the volume of manuscripts submitted for publication growing every year, the deficiencies of peer review (e.g. long review times) are becoming more apparent. Editorial strategies, sets of guidelines designed to speed up the process and reduce editors' workloads, are treated as trade secrets by publishing houses and are not shared publicly. To improve the effectiveness of their strategies, editors in small publishing groups are faced with undertaking an iterative trial-and-error approach. We show that Cartesian Genetic Programming, a nature-inspired evolutionary algorithm, can dramatically improve editorial strategies. The artificially evolved strategy reduced the duration of the peer review process by 30%, without increasing the pool of reviewers (in comparison to a typical human-developed strategy). Evolutionary computation has typically been used in technological processes or biological ecosystems. Our results demonstrate that genetic programs can improve real-world social systems that are usually much harder to understand and control than physical systems.

40 CFR 428.90 - Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., dry digestion, and mechanical reclaimed rubber subcategory. 428.90 Section 428.90 Protection of... MANUFACTURING POINT SOURCE CATEGORY Pan, Dry Digestion, and Mechanical Reclaimed Rubber Subcategory § 428.90 Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory. The...

40 CFR 428.90 - Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., dry digestion, and mechanical reclaimed rubber subcategory. 428.90 Section 428.90 Protection of... MANUFACTURING POINT SOURCE CATEGORY Pan, Dry Digestion, and Mechanical Reclaimed Rubber Subcategory § 428.90 Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory. The...

40 CFR 428.90 - Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., dry digestion, and mechanical reclaimed rubber subcategory. 428.90 Section 428.90 Protection of... MANUFACTURING POINT SOURCE CATEGORY Pan, Dry Digestion, and Mechanical Reclaimed Rubber Subcategory § 428.90 Applicability; description of the pan, dry digestion, and mechanical reclaimed rubber subcategory. The...

Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study.

PubMed

Tammemagi, Martin C; Schmidt, Heidi; Martel, Simon; McWilliams, Annette; Goffin, John R; Johnston, Michael R; Nicholas, Garth; Tremblay, Alain; Bhatia, Rick; Liu, Geoffrey; Soghrati, Kam; Yasufuku, Kazuhiro; Hwang, David M; Laberge, Francis; Gingras, Michel; Pasian, Sergio; Couture, Christian; Mayo, John R; Nasute Fauerbach, Paola V; Atkar-Khattra, Sukhinder; Peacock, Stuart J; Cressman, Sonya; Ionescu, Diana; English, John C; Finley, Richard J; Yee, John; Puksa, Serge; Stewart, Lori; Tsai, Scott; Haider, Ehsan; Boylan, Colm; Cutz, Jean-Claude; Manos, Daria; Xu, Zhaolin; Goss, Glenwood D; Seely, Jean M; Amjadi, Kayvan; Sekhon, Harmanjatinder S; Burrowes, Paul; MacEachern, Paul; Urbanski, Stefan; Sin, Don D; Tan, Wan C; Leighl, Natasha B; Shepherd, Frances A; Evans, William K; Tsao, Ming-Sound; Lam, Stephen

2017-11-01

Results from retrospective studies indicate that selecting individuals for low-dose CT lung cancer screening on the basis of a highly predictive risk model is superior to using criteria similar to those used in the National Lung Screening Trial (NLST; age, pack-year, and smoking quit-time). We designed the Pan-Canadian Early Detection of Lung Cancer (PanCan) study to assess the efficacy of a risk prediction model to select candidates for lung cancer screening, with the aim of determining whether this approach could better detect patients with early, potentially curable, lung cancer. We did this single-arm, prospective study in eight centres across Canada. We recruited participants aged 50-75 years, who had smoked at some point in their life (ever-smokers), and who did not have a self-reported history of lung cancer. Participants had at least a 2% 6-year risk of lung cancer as estimated by the PanCan model, a precursor to the validated PLCOm2012 model. Risk variables in the model were age, smoking duration, pack-years, family history of lung cancer, education level, body-mass index, chest x-ray in the past 3 years, and history of chronic obstructive pulmonary disease. Individuals were screened with low-dose CT at baseline (T0), and at 1 (T1) and 4 (T4) years post-baseline. The primary outcome of the study was incidence of lung cancer. This study is registered with ClinicalTrials.gov, number NCT00751660. 7059 queries came into the study coordinating centre and were screened for PanCan risk. 15 were duplicates, so 7044 participants were considered for enrolment. Between Sept 24, 2008, and Dec 17, 2010, we recruited and enrolled 2537 eligible ever-smokers. After a median follow-up of 5·5 years (IQR 3·2-6·1), 172 lung cancers were diagnosed in 164 individuals (cumulative incidence 0·065 [95% CI 0·055-0·075], incidence rate 138·1 per 10 000 person-years [117·8-160·9]). There were ten interval lung cancers (6% of lung cancers and 6% of individuals with cancer

Comparative Pan-Genome Analysis of Piscirickettsia salmonis Reveals Genomic Divergences within Genogroups.

PubMed

Nourdin-Galindo, Guillermo; Sánchez, Patricio; Molina, Cristian F; Espinoza-Rojas, Daniela A; Oliver, Cristian; Ruiz, Pamela; Vargas-Chacoff, Luis; Cárcamo, Juan G; Figueroa, Jaime E; Mancilla, Marcos; Maracaja-Coutinho, Vinicius; Yañez, Alejandro J

2017-01-01

Piscirickettsia salmonis is the etiological agent of salmonid rickettsial septicemia, a disease that seriously affects the salmonid industry. Despite efforts to genomically characterize P. salmonis , functional information on the life cycle, pathogenesis mechanisms, diagnosis, treatment, and control of this fish pathogen remain lacking. To address this knowledge gap, the present study conducted an in silico pan-genome analysis of 19 P. salmonis strains from distinct geographic locations and genogroups. Results revealed an expected open pan-genome of 3,463 genes and a core-genome of 1,732 genes. Two marked genogroups were identified, as confirmed by phylogenetic and phylogenomic relationships to the LF-89 and EM-90 reference strains, as well as by assessments of genomic structures. Different structural configurations were found for the six identified copies of the ribosomal operon in the P. salmonis genome, indicating translocation throughout the genetic material. Chromosomal divergences in genomic localization and quantity of genetic cassettes were also found for the Dot/Icm type IVB secretion system. To determine divergences between core-genomes, additional pan-genome descriptions were compiled for the so-termed LF and EM genogroups. Open pan-genomes composed of 2,924 and 2,778 genes and core-genomes composed of 2,170 and 2,228 genes were respectively found for the LF and EM genogroups. The core-genomes were functionally annotated using the Gene Ontology, KEGG, and Virulence Factor databases, revealing the presence of several shared groups of genes related to basic function of intracellular survival and bacterial pathogenesis. Additionally, the specific pan-genomes for the LF and EM genogroups were defined, resulting in the identification of 148 and 273 exclusive proteins, respectively. Notably, specific virulence factors linked to adherence, colonization, invasion factors, and endotoxins were established. The obtained data suggest that these genes could be

Comparative Pan-Genome Analysis of Piscirickettsia salmonis Reveals Genomic Divergences within Genogroups

PubMed Central

Nourdin-Galindo, Guillermo; Sánchez, Patricio; Molina, Cristian F.; Espinoza-Rojas, Daniela A.; Oliver, Cristian; Ruiz, Pamela; Vargas-Chacoff, Luis; Cárcamo, Juan G.; Figueroa, Jaime E.; Mancilla, Marcos; Maracaja-Coutinho, Vinicius; Yañez, Alejandro J.

2017-01-01

Piscirickettsia salmonis is the etiological agent of salmonid rickettsial septicemia, a disease that seriously affects the salmonid industry. Despite efforts to genomically characterize P. salmonis, functional information on the life cycle, pathogenesis mechanisms, diagnosis, treatment, and control of this fish pathogen remain lacking. To address this knowledge gap, the present study conducted an in silico pan-genome analysis of 19 P. salmonis strains from distinct geographic locations and genogroups. Results revealed an expected open pan-genome of 3,463 genes and a core-genome of 1,732 genes. Two marked genogroups were identified, as confirmed by phylogenetic and phylogenomic relationships to the LF-89 and EM-90 reference strains, as well as by assessments of genomic structures. Different structural configurations were found for the six identified copies of the ribosomal operon in the P. salmonis genome, indicating translocation throughout the genetic material. Chromosomal divergences in genomic localization and quantity of genetic cassettes were also found for the Dot/Icm type IVB secretion system. To determine divergences between core-genomes, additional pan-genome descriptions were compiled for the so-termed LF and EM genogroups. Open pan-genomes composed of 2,924 and 2,778 genes and core-genomes composed of 2,170 and 2,228 genes were respectively found for the LF and EM genogroups. The core-genomes were functionally annotated using the Gene Ontology, KEGG, and Virulence Factor databases, revealing the presence of several shared groups of genes related to basic function of intracellular survival and bacterial pathogenesis. Additionally, the specific pan-genomes for the LF and EM genogroups were defined, resulting in the identification of 148 and 273 exclusive proteins, respectively. Notably, specific virulence factors linked to adherence, colonization, invasion factors, and endotoxins were established. The obtained data suggest that these genes could be

77 FR 40147 - Pan Am Southern, LLC.-Abandonment Exemption-in Worcester County, MA; Springfield Terminal Railway...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... (Sub No. 41X)] Pan Am Southern, LLC.--Abandonment Exemption--in Worcester County, MA; Springfield Terminal Railway Company--Discontinuance of Service Exemption--in Worcester County, MA Pan Am Southern, LLC... B. Burns, Corporate Counsel, Iron Horse Park, North Billerica, MA 01862. If the verified notice...

Mass spectral determination of phenylacetonitrile (PAN) levels in body tissues of adult desert locust, Schistocerca gregaria

USDA-ARS?s Scientific Manuscript database

: Wings and legs of the gregarious desert locust, Schistocerca gregaria have been shown to be release sites of phenylacetonitrile (PAN), the major adult male-produced pheromone. However, there is limited information on the distribution of PAN within the locust. Here we show, using gas chromatograph...

Pan-sharpening algorithm to remove thin cloud via mask dodging and nonsampled shift-invariant shearlet transform

NASA Astrophysics Data System (ADS)

Shi, Cheng; Liu, Fang; Li, Ling-Ling; Hao, Hong-Xia

2014-01-01

The goal of pan-sharpening is to get an image with higher spatial resolution and better spectral information. However, the resolution of the pan-sharpened image is seriously affected by the thin clouds. For a single image, filtering algorithms are widely used to remove clouds. These kinds of methods can remove clouds effectively, but the detail lost in the cloud removal image is also serious. To solve this problem, a pan-sharpening algorithm to remove thin cloud via mask dodging and nonsampled shift-invariant shearlet transform (NSST) is proposed. For the low-resolution multispectral (LR MS) and high-resolution panchromatic images with thin clouds, a mask dodging method is used to remove clouds. For the cloud removal LR MS image, an adaptive principal component analysis transform is proposed to balance the spectral information and spatial resolution in the pan-sharpened image. Since the clouds removal process causes the detail loss problem, a weight matrix is designed to enhance the details of the cloud regions in the pan-sharpening process, but noncloud regions remain unchanged. And the details of the image are obtained by NSST. Experimental results over visible and evaluation metrics demonstrate that the proposed method can keep better spectral information and spatial resolution, especially for the images with thin clouds.

EDITORIAL: Incoming Editor-in-Chief

NASA Astrophysics Data System (ADS)

Webb, Steve

2006-01-01

Physics in Medicine and Biology (PMB) is a journal that originated in the UK but is now rightly regarded as one of the pre-eminent international journals for the publication of material coming within its remit. It is 50 years old and its maturity is an outcome of the consistent support of high performing authors, a supportive and professional publishing house, dedicated referees, many vigorous and conscientious editorial boards and the collective input of the 10 previous Editors as listed in his incoming editorial (January 2000 issue) by the retiring Editor, Professor Alun Beddoe. The scientific climate and it associated publication modus operandi in the 1950s was very different from that at the current time and the journal has evolved to reflect this. Hence today the scope of content is somewhat broader, the size of the journal is vastly greater, the whole publication process is slicker and more efficient and a paper in PMB is highly prized by its authors and those who look to quality factors and impact. The quality of the journal still relies on the voluntary labour and expertise of its busy international referees and Board members. For many years I have tried to place my own research material in PMB and encourage my teams to do likewise, not only acknowledging the prestige of the journal but also because of the extraordinarily fast turnaround time of all the processes without any loss of quality. This serves us very well and the publishing team are to be congratulated. Some things seem to change more slowly or not at all, however. The prediction, when I started my research career, that books and journals would be dinosaurs by now has manifestly not come true and, whilst most of us are addicted (and why not?) to the electronic ways of doing things that can be done by more traditional ways, PMB and a packet of reprints from time to time arriving by post still has a reassuring feel despite the fact that the papers have been `on-line' for a while before. An incoming

PAN AIR summary document (version 1.0)

NASA Technical Reports Server (NTRS)

Derbyshire, T.; Sidwell, K. W.

1982-01-01

The capabilities and limitations of the panel aerodynamics (PAN AIR) computer program system are summarized. This program uses a higher order panel method to solve boundary value problems involving the Prandtl-Glauert equation for subsonic and supersonic potential flows. Both aerodynamic and hydrodynamic problems can be solved using this modular software which is written for the CDC 6600 and 7600, and the CYBER 170 series computers.

The Pan-STARRS Survey for Transients (PSST)

NASA Astrophysics Data System (ADS)

Huber, Mark; Carter Chambers, Kenneth; Flewelling, Heather; Smartt, Stephen J.; Smith, Ken; Wright, Darryl

2015-08-01

The Pan-STARRS1 (PS1) Science Consortium finished the 3Pi survey of the whole sky north of -30 degrees between 2010-2014 in grizy (PS1 specific filters) and the PS1 telescope has been running a wide-field survey for near earth objects, funded by NASA through the NEO Observation Program. This survey takes data in a w-band (wide-band filter spanning g,r,i) in dark time, and combinations of r, i, z and y during bright time. We are now processing these data through the Pan-STARRS IPP difference imaging pipeline and recovering stationary transients. Effectively the 3Pi survey for transients that started during the PS1 Science Consortium is being continued under the new NEO optimized operations mode. The observing procedure in this case is to take a quad of exposures, typically 30-45 seconds separated by 10-20 minutes each, typically revealing high confidence transients (greater than 5-sigma) to depths of i~ 20.7, y~18.3 (AB mags). This cadence may be repeated on subsequent nights in a return pointing.Continuing the public release of the first 880 transients from the PS1 3Pi survey during the search period September 2013 - January 2014, beginning February 2015, the transient events using the data from the the Pan-STARRS NEO Science Consortium are now regularly added. These are mostly supernova candidates, but the list also contains some variable stars, AGN, and nuclear transients. The light curves are too sparsely sampled to be of standalone use, but they may be of use to the community in combining with existing data (e.g. Fraser et al. 2013, ApJ, 779, L8), constraining explosion and rise times (e.g. Nicholl et al. 2013, Nature, 502, 346) as well as many being new discoveries.For additional details visit http://star.pst.qub.ac.uk/ps1threepi/

Pan-American Health Organization CD-ROM Pilot Project.

ERIC Educational Resources Information Center

Brito, Claudio J.

1987-01-01

Examines the difficulties faced by the implementors of information dissemination systems in developing nations and explores the possible use of optical data disk technologies to overcome them. A pilot project of the Pan American Health Organization for the production of a CD-ROM containing bibliographic references on public health is described.…

An editor for the generation and customization of geometry restraints

DOE PAGES

Moriarty, Nigel W.; Draizen, Eli J.; Adams, Paul D.

2017-02-01

Chemical restraints for use in macromolecular structure refinement are produced by a variety of methods, including a number of programs that use chemical information to generate the required bond, angle, dihedral, chiral and planar restraints. These programs help to automate the process and therefore minimize the errors that could otherwise occur if it were performed manually. Furthermore, restraint-dictionary generation programs can incorporate chemical and other prior knowledge to provide reasonable choices of types and values. However, the use of restraints to define the geometry of a molecule is an approximation introduced with efficiency in mind. The representation of a bondmore » as a parabolic function is a convenience and does not reflect the true variability in even the simplest of molecules. Another complicating factor is the interplay of the molecule with other parts of the macromolecular model. Finally, difficult situations arise from molecules with rare or unusual moieties that may not have their conformational space fully explored. These factors give rise to the need for an interactive editor for WYSIWYG interactions with the restraints and molecule. Restraints Editor, Especially Ligands (REEL) is a graphical user interface for simple and error-free editing along with additional features to provide greater control of the restraint dictionaries in macromolecular refinement.« less

An editor for the generation and customization of geometry restraints.

PubMed

Moriarty, Nigel W; Draizen, Eli J; Adams, Paul D

2017-02-01

Chemical restraints for use in macromolecular structure refinement are produced by a variety of methods, including a number of programs that use chemical information to generate the required bond, angle, dihedral, chiral and planar restraints. These programs help to automate the process and therefore minimize the errors that could otherwise occur if it were performed manually. Furthermore, restraint-dictionary generation programs can incorporate chemical and other prior knowledge to provide reasonable choices of types and values. However, the use of restraints to define the geometry of a molecule is an approximation introduced with efficiency in mind. The representation of a bond as a parabolic function is a convenience and does not reflect the true variability in even the simplest of molecules. Another complicating factor is the interplay of the molecule with other parts of the macromolecular model. Finally, difficult situations arise from molecules with rare or unusual moieties that may not have their conformational space fully explored. These factors give rise to the need for an interactive editor for WYSIWYG interactions with the restraints and molecule. Restraints Editor, Especially Ligands (REEL) is a graphical user interface for simple and error-free editing along with additional features to provide greater control of the restraint dictionaries in macromolecular refinement.

Role of Peroxyacyl Nitrates (PANs) Species in Tropospheric Chemistry in the Southeastern U.S. during SOAS 2013

NASA Astrophysics Data System (ADS)

Toma, S.; Bertman, S. B.; Xiong, F.; Shepson, P. B.; Romer, P.; Duffey, K.; Wooldridge, P. J.; Cohen, R. C.; Baumann, K.

2014-12-01

Measurements of PANs, mainly focused on peroxyacetyl nitrate (PAN), peroxypropinoyl nitrate (PPN), and peroxymethacryloyl nitrate (MPAN), were made during the Southern Oxidant and Aerosol Study (SOAS) from June 1 to July 15, 2013 at the SEARCH ground site in Centerville, Alabama. Grab samples were measured at ground level by GC­ECD every 20 min. Since emissions of biogenic volatile organic compounds in the Southeast are high and there are a variety of anthropogenic pollution sources in the area, the location allows the study of biogenic/anthropogenic interactions. PANs showed a diurnal behavior with double peaks around noon and again at the end of the afternoon. Mean mixing ratios during the daytime were 178, 5, and 9 pptv for PAN, PPN, and MPAN respectively with highest levels in air from the North. The ratios of PPN or MPAN with PAN are used to predict the relative importance of biogenic and anthropogenic VOC sources. It appears that biogenic VOC sources were slightly more important. The concentrations measured in 2013 are lower than levels at similar sites in the Southeastern U.S. made over the last 20 years. A comparison is made to assess the role of changes in NOx emissions in the Southeastern U.S and resultant photoproducts like PANs and ozone. While absolute levels of PANs are lower, the relative amount MPAN is similar at Centreville while the relative amount of PPN decreased dramatically. This suggests that the impact of anthropogenic VOC emissions on the atmospheric chemistry seen in Centerville, 2013 was lower than seen in the SE previously. Recent laboratory experiments have suggested that the hydroxynitrate of MPAN could be a main precursor to formation of secondary organic aerosol. Field data of speciated MPAN along with particle values, including particulate nitrogen, will allow the relationship between gas phase MPAN and aerosol composition to be explored.

Modeling the motion and orientation of various pharmaceutical tablet shapes in a film coating pan using DEM.

PubMed

Ketterhagen, William R

2011-05-16

Film coating uniformity is an important quality attribute of pharmaceutical tablets. Large variability in coating thickness can limit process efficiency or cause significant variation in the amount or delivery rate of the active pharmaceutical ingredient to the patient. In this work, the discrete element method (DEM) is used to computationally model the motion and orientation of several novel pharmaceutical tablet shapes in a film coating pan in order to predict coating uniformity. The model predictions are first confirmed with experimental data obtained from an equivalent film coating pan using a machine vision system. The model is then applied to predict coating uniformity for various tablet shapes, pan speeds, and pan loadings. The relative effects of these parameters on both inter- and intra-tablet film coating uniformity are assessed. The DEM results show intra-tablet coating uniformity is strongly influenced by tablet shape, and the extent of this can be predicted by a measure of the tablet shape. The tablet shape is shown to have little effect on the mixing of tablets, and thus, the inter-tablet coating uniformity. The pan rotation speed and pan loading are shown to have a small effect on intra-tablet coating uniformity but a more significant impact on inter-tablet uniformity. These results demonstrate the usefulness of modeling in guiding drug product development decisions such as selection of tablet shape and process operating conditions. Copyright © 2011 Elsevier B.V. All rights reserved.

Towards new constraints on the impacts of fires on air quality and the nitrogen cycle: Extending the nadir satellite record of peroxyacetyl nitrate (PAN) with CrIS

NASA Astrophysics Data System (ADS)

Fischer, E. V.; Payne, V.; Kulawik, S. S.; Fu, D.

2017-12-01

Peroxyacetyl nitrate (PAN) plays a critical role both in atmospheric chemistry and in the redistribution of nitrogen in the troposphere. As a thermally unstable reservoir for nitrogen oxide radicals (NOx) PAN allows NOxto be transported large distances from the original source, thereby extending the range of air quality impacts from fires. Satellite measurements of PAN from the nadir-viewing Aura Tropospheric Emission Spectrometer (TES) have shown large enhancements in PAN associated with fires, and have recently been used to shed new light on the role of fires, PAN precursor emissions and dynamics on the global distribution of PAN and long-range transport of ozone. TES PAN retrievals have also been used to explore interannual variability in PAN mixing ratios in the Western US. The Cross-track Infrared Sounder (CrIS) on S-NPP and the upcoming JPSS series provides a means to continue the satellite record of PAN from the nadir view, with increased spatial coverage. Retrievals of PAN from TES have so far relied on the PAN absorption feature centered at 1150 cm-1, a spectral region not covered by CrIS. Our team has recently developed an approach that would allow the use of another PAN spectral feature centered at 790 cm-1, a spectral region that is covered by CrIS. Here, we apply this approach to CrIS spectra and compare the characteristics of the CrIS PAN retrievals, including vertical sensitivity and uncertainty estimates, with those of the TES PAN product. The CrIS PAN measurements can offer improved spatial coverage, extend the existing satellite PAN record and provide new opportunities for validation of satellite PAN retrievals.

René Marcelle (December 30, 1931-December 18, 2011), the first editor-in-chief of Photosynthesis Research.

PubMed

Govindjee; Marcelle, Dominique

2016-07-01

This tribute honors the first editor-in-chief of Photosynthesis Research, René Marcelle the Belgian plant physiologist who, with publishers in The Netherlands, launched the journal in 1980. Here, we present a glimpse of René Marcelle's early life, his education and research, as well as his editorial work for the journal and other conferences in plant physiology. He worked on control of photosynthesis, both the biological and environmental aspects, as well as on crassulacean acid metabolism. He is best remembered as a kind-hearted and humane editor.

VizieR Online Data Catalog: Companions to nearby stars from Pan-STARRS 1 (Deacon+, 2014)

NASA Astrophysics Data System (ADS)

Deacon, N. R.; Liu, M. C.; Magnier, E. A.; Aller, K. M.; Best, W. M. J.; Dupuy, T.; Bowler, B. P.; Mann, A. W.; Redstone, J. A.; Burgett, W. S.; Chambers, K. C.; Draper, P. W.; Flewelling, H.; Hodapp, K. W.; Kaiser, N.; Kudritzki, R.-P.; Morgan, J. S.; Metcalfe, N.; Price, P. A.; Tonry, J. L.; Wainscoat, R. J.

2017-04-01

Pan-STARRS 1 is a wide-field 1.8m telescope situated on Haleakala on Maui in the Hawaiian Islands. Run by a consortium of astronomical research institutions, it has been surveying the sky north of δ=-30° since 2010 May. Just over half of the telescope's operating time is reserved for the 3π Survey, a multi-filter, multi-epoch survey of three-fourths of the sky (~30,000 deg2). We conducted our search over several iterations of the Pan-STARRS 1 3π database. In all our searches we queried the most up-to-date Pan-STARRS 1 3π database using the Desktop Virtual Observatory software (Magnier et al. 2008, IAU Symp. 248, A Giant Step: from Milli- to Micro-arcsecond Astrometry (Cambridge: Cambridge Univ. Press), 553). Initially, our search involved combining 2MASS and Pan-STARRS 1 data to calculate proper motions in a similar process to that used by Deacon et al. (2011, J/AJ/142/77). For this PS1 + 2MASS search, we required that objects had more than one detection in the yP1 band. PS1 detections were required to have a significance greater than 5σ to be included in the astrometric and photometric solutions of their parent object. We also required that the objects be classified as good quality, point-source detections in both Pan-STARRS 1 and 2MASS. (10 data files).

THE NEW ONLINE METADATA EDITOR FOR GENERATING STRUCTURED METADATA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Devarakonda, Ranjeet; Shrestha, Biva; Palanisamy, Giri

Nobody is better suited to describe data than the scientist who created it. This description about a data is called Metadata. In general terms, Metadata represents the who, what, when, where, why and how of the dataset [1]. eXtensible Markup Language (XML) is the preferred output format for metadata, as it makes it portable and, more importantly, suitable for system discoverability. The newly developed ORNL Metadata Editor (OME) is a Web-based tool that allows users to create and maintain XML files containing key information, or metadata, about the research. Metadata include information about the specific projects, parameters, time periods, andmore » locations associated with the data. Such information helps put the research findings in context. In addition, the metadata produced using OME will allow other researchers to find these data via Metadata clearinghouses like Mercury [2][4]. OME is part of ORNL s Mercury software fleet [2][3]. It was jointly developed to support projects funded by the United States Geological Survey (USGS), U.S. Department of Energy (DOE), National Aeronautics and Space Administration (NASA) and National Oceanic and Atmospheric Administration (NOAA). OME s architecture provides a customizable interface to support project-specific requirements. Using this new architecture, the ORNL team developed OME instances for USGS s Core Science Analytics, Synthesis, and Libraries (CSAS&L), DOE s Next Generation Ecosystem Experiments (NGEE) and Atmospheric Radiation Measurement (ARM) Program, and the international Surface Ocean Carbon Dioxide ATlas (SOCAT). Researchers simply use the ORNL Metadata Editor to enter relevant metadata into a Web-based form. From the information on the form, the Metadata Editor can create an XML file on the server that the editor is installed or to the user s personal computer. Researchers can also use the ORNL Metadata Editor to modify existing XML metadata files. As an example, an NGEE Arctic scientist use OME to

Curbing Early-Career Teacher Attrition: A Pan-Canadian Document Analysis of Teacher Induction and Mentorship Programs

ERIC Educational Resources Information Center

Kutsyuruba, Benjamin; Tregunna, Leigha

2014-01-01

Over the past two decades, the phenomenon of teachers abandoning the profession has been noted internationally, and has increasingly caught the attention of policy makers and educational leaders. Despite this awareness, no pan-Canadian statistics or comprehensive reviews are available. This paper reports on the exploratory, pan-Canadian document…

Can Chimpanzees ("Pan troglodytes") Discriminate Appearance from Reality?

ERIC Educational Resources Information Center

Krachun, Carla; Call, Josep; Tomasello, Michael

2009-01-01

A milestone in human development is coming to recognize that how something looks is not necessarily how it is. We tested appearance-reality understanding in chimpanzees ("Pan troglodytes") with a task requiring them to choose between a small grape and a big grape. The apparent relative size of the grapes was reversed using magnifying and…

Life and times of the impact factor: retrospective analysis of trends for seven medical journals (1994-2005) and their Editors' views

PubMed Central

Chew, Mabel; Villanueva, Elmer V; Van Der Weyden, Martin B

2007-01-01

Objective (1) To analyse trends in the journal impact factor (IF) of seven general medical journals (Ann Intern Med, BMJ, CMAJ, JAMA, Lancet, Med J Aust and N Engl J Med) over 12 years; and (2) to ascertain the views of these journals' past and present Editors on factors that had affected their journals' IFs during their tenure, including direct editorial policies. Design Retrospective analysis of IF data from ISI Web of Knowledge Journal Citation Reports—Science Edition, 1994 to 2005, and interviews with Editors-in-Chief. Setting Medical journal publishing. Participants Ten Editors-in-Chief of the journals, except Med J Aust, who served between 1999 and 2004. Main outcome measures IFs and component numerator and denominator data for the seven general medical journals (1994 to 2005) were collected. IFs are calculated using the formula: (Citations in year z to articles published in years x and y)/(Number of citable articles published in years x and y), where z is the current year and x and y are the previous two years. Editors' views on factors that had affected their journals' IFs were also obtained. Results IFs generally rose over the 12-year period, with the N Engl J Med having the highest IF throughout. However, percentage rises in IF relative to the baseline year of 1994 were greatest for CMAJ (about 500%) and JAMA (260%). Numerators for most journals tended to rise over this period, while denominators tended to be stable or to fall, although not always in a linear fashion. Nine of ten eligible editors were interviewed. Possible reasons given for rises in citation counts included: active recruitment of high-impact articles by courting researchers; offering authors better services; boosting the journal's media profile; more careful article selection; and increases in article citations. Most felt that going online had not affected citations. Most had no deliberate policy to publish fewer articles (lowering the IF denominator), which was sometimes the unintended

Using pan-sharpened high resolution satellite data to improve impervious surfaces estimation

NASA Astrophysics Data System (ADS)

Xu, Ru; Zhang, Hongsheng; Wang, Ting; Lin, Hui

2017-05-01

Impervious surface is an important environmental and socio-economic indicator for numerous urban studies. While a large number of researches have been conducted to estimate the area and distribution of impervious surface from satellite data, the accuracy for impervious surface estimation (ISE) is insufficient due to high diversity of urban land cover types. This study evaluated the use of panchromatic (PAN) data in very high resolution satellite image for improving the accuracy of ISE by various pan-sharpening approaches, with a further comprehensive analysis of its scale effects. Three benchmark pan-sharpening approaches, Gram-Schmidt (GS), PANSHARP and principal component analysis (PCA) were applied to WorldView-2 in three spots of Hong Kong. The on-screen digitization were carried out based on Google Map and the results were viewed as referenced impervious surfaces. The referenced impervious surfaces and the ISE results were then re-scaled to various spatial resolutions to obtain the percentage of impervious surfaces. The correlation coefficient (CC) and root mean square error (RMSE) were adopted as the quantitative indicator to assess the accuracy. The accuracy differences between three research areas were further illustrated by the average local variance (ALV) which was used for landscape pattern analysis. The experimental results suggested that 1) three research regions have various landscape patterns; 2) ISE accuracy extracted from pan-sharpened data was better than ISE from original multispectral (MS) data; and 3) this improvement has a noticeable scale effects with various resolutions. The improvement was reduced slightly as the resolution became coarser.

Cryoconite pans on Snowball Earth: supraglacial oases for Cryogenian eukaryotes?

PubMed

Hoffman, P F

2016-11-01

Geochemical, paleomagnetic, and geochronological data increasingly support the Snowball Earth hypothesis for Cryogenian glaciations. Yet, the fossil record reveals no clear-cut evolutionary bottleneck. Climate models and the modern cryobiosphere offer insights on this paradox. Recent modeling implies that Snowball continents never lacked ice-free areas. Wind-blown dust from these areas plus volcanic ash were trapped by snow on ice sheets and sea ice. At a Snowball onset, sea ice was too thin to flow and ablative ice was too cold for dust retention. After a few millenia, sea ice reached 100 s of meters in thickness and began to flow as a 'sea glacier' toward an equatorial ablation zone. At first, dust advected to the ablative surface was recycled by winds, but as the surface warmed with rising CO 2 , dust aka cryoconite began to accumulate. As a sea glacier has no terminus, cryoconite saturated the surface. It absorbed solar radiation, supported cyanobacterial growth, and sank to an equilibrium depth forming holes and decameter-scale pans of meltwater. As meltwater production rose, drainages developed, connecting pans to moulins, where meltwater was flushed into the subglacial ocean. Flushing cleansed the surface, creating a stabilizing feedback. If the dust flux rose, cryoconite was removed; if the dust flux waned, cryoconite accumulated. In addition to cyanobacteria, modern cryoconite holes are inhabited by green algae, fungi, protists, and certain metazoans. On Snowball Earth, cryoconite pans provided stable interconnected habitats for eukaryotes tolerant of fresh to brackish cold water on an ablation surface 60 million km 2 in area. Flushing and burial of organic matter was a potential source of atmospheric oxygen. Dominance of green algae among Ediacaran eukaryotic primary producers is a possible legacy of Cryogenian cryoconite pans, but a schizohaline ocean-supraglacial freshwater and subglacial brine-may have exerted selective stress on early metazoans, or

PanDA for ATLAS distributed computing in the next decade

NASA Astrophysics Data System (ADS)

Barreiro Megino, F. H.; De, K.; Klimentov, A.; Maeno, T.; Nilsson, P.; Oleynik, D.; Padolski, S.; Panitkin, S.; Wenaus, T.; ATLAS Collaboration

2017-10-01

The Production and Distributed Analysis (PanDA) system has been developed to meet ATLAS production and analysis requirements for a data-driven workload management system capable of operating at the Large Hadron Collider (LHC) data processing scale. Heterogeneous resources used by the ATLAS experiment are distributed worldwide at hundreds of sites, thousands of physicists analyse the data remotely, the volume of processed data is beyond the exabyte scale, dozens of scientific applications are supported, while data processing requires more than a few billion hours of computing usage per year. PanDA performed very well over the last decade including the LHC Run 1 data taking period. However, it was decided to upgrade the whole system concurrently with the LHC’s first long shutdown in order to cope with rapidly changing computing infrastructure. After two years of reengineering efforts, PanDA has embedded capabilities for fully dynamic and flexible workload management. The static batch job paradigm was discarded in favor of a more automated and scalable model. Workloads are dynamically tailored for optimal usage of resources, with the brokerage taking network traffic and forecasts into account. Computing resources are partitioned based on dynamic knowledge of their status and characteristics. The pilot has been re-factored around a plugin structure for easier development and deployment. Bookkeeping is handled with both coarse and fine granularities for efficient utilization of pledged or opportunistic resources. An in-house security mechanism authenticates the pilot and data management services in off-grid environments such as volunteer computing and private local clusters. The PanDA monitor has been extensively optimized for performance and extended with analytics to provide aggregated summaries of the system as well as drill-down to operational details. There are as well many other challenges planned or recently implemented, and adoption by non-LHC experiments such

Publication Criteria and Recommended Areas of Improvement within School Psychology Journals as Reported by Editors, Journal Board Members, and Manuscript Authors

ERIC Educational Resources Information Center

Albers, Craig A.; Floyd, Randy G.; Fuhrmann, Melanie J.; Martinez, Rebecca S.

2011-01-01

Two online surveys were completed by editors, associate editors, editorial board members, and members or fellows of the Division 16 of the American Psychological Association. These surveys targeted (a) the criteria for a manuscript to be published in school psychology journals, and (b) the components of the peer-review process that should be…

Detectability of Chelyabinsk-like impactors with Pan-STARRS

NASA Astrophysics Data System (ADS)

Micheli, Marco; Wainscoat, Richard J.; Denneau, Larry

2018-03-01

In this work we present the results of our analysis of the detectability of an object in the size range of the recent Chelyabinsk impactor under the current discovery and follow-up capabilities, using the specific observational strategy of the Pan-STARRS survey as a reference point. We first discuss the observability of real-life cases inspired by the impact trajectories of 2008 TC3, 2014 AA, the past Earth encounters with 2014 RC and 2015 TB145, the upcoming fly-by of 2012 TC4 and the Chelyabinsk event. We then expand our analysis with the investigation of synthetic impactors with realistic orbital distributions. Among the various conclusions of our analysis, we discuss how the time of first detectability of an object does not necessarily correspond to the moment when that same object can be recognized as an impactor. We also point out how objects discovered only a few days before impact can be immediately identified as impactors, partly thanks to the good astrometric quality that telescopes like Pan-STARRS currently achieve.

Implementation of the Pan-STARRS Image Processing Pipeline

NASA Astrophysics Data System (ADS)

Fang, Julia; Aspin, C.

2007-12-01

Pan-STARRS, or Panoramic Survey Telescope and Rapid Response System, is a wide-field imaging facility that combines small mirrors with gigapixel cameras. It surveys the entire available sky several times a month, which ultimately requires large amounts of data to be processed and stored right away. Accordingly, the Image Processing Pipeline--the IPP--is a collection of software tools that is responsible for the primary image analysis for Pan-STARRS. It includes data registration, basic image analysis such as obtaining master images and detrending the exposures, mosaic calibration when applicable, and lastly, image sum and difference. In this paper I present my work of the installation of IPP 2.1 and 2.2 on a Linux machine, running the Simtest, which is simulated data to test your installation, and finally applying the IPP to two different sets of UH 2.2m Tek data. This work was conducted by a Research Experience for Undergraduates (REU) position at the University of Hawaii's Institute for Astronomy and funded by the NSF.

Xe/Kr Selectivity Measurements using AgZ-PAN at Various Temperatures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garn, Troy Gerry; Greenhalgh, Mitchell Randy; Watson, Tony Leroy

2015-05-01

In preparation for planned FY-15 Xe/Kr multi-column testing, a series of experiments were performed to determine the selectivity of Xe over Kr using the silver converted mordenite-polyacrylonitrile (AgZ-PAN) sorbent. Results from these experiments will be used for parameter selection guidelines to define test conditions for Kr gas capture purity evaluations later this year. The currently configured experimental test bed was modified by installing a new cooling apparatus to permit future multi-column testing with independent column temperature control. The modified test bed will allow for multi-column testing to facilitate a Xe separation followed by a Kr separation using engineered form sorbents.more » Selectivity experiments were run at temperatures of 295, 250 and 220 K. Two feed gas compositions of 1000 ppmv Xe, 150 ppmv Kr in either a He or an air balance were used. AgZ-PAN sorbent selectivity was calculated using Xe and Kr capacity determinations. AgZ-PAN sorbent selectivities for Xe over Kr of 72 were calculated at room temperature (295 K) using the feed gas with a He balance and 34 using the feed gas with an air balance. As the test temperatures were decreased the selectivity of Xe over Kr also decreased due to an increase in both Xe and Kr capacities. At 220 K, the sorbent selectivities for Xe over Kr were 22 using the feed gas with a He balance and 28 using the feed gas with an air balance. The selectivity results indicate that AgZ-PAN used in the first column of a multi-column configuration will provide adequate partitioning of Xe from Kr in the tested temperature range to produce a more pure Kr end product for collection.« less

Persnickety editor, Founding Father, Mentor and Friend: The Legacy of Fred Mumpton

NASA Technical Reports Server (NTRS)

Ming, Douglas W.

2006-01-01

This paper is a tribute to Dr Fred Munpton, the founder of the International Committee on Natural Zeolites (ICNZ), by one of his students, who later succeed him as president of the ICNZ. The tribute reflects on Dr. Mumpton's skills as an editor and his zeal for the study of natural zeolites.

Stories of Three Editors: A Qualitative Study of Editing in the Workplace.

ERIC Educational Resources Information Center

Thompson, Isabelle K.; Rothschild, Joyce M.

1995-01-01

Presents generalizations about the editing process in a governmental agency. Suggests that editing is a complex, meaning-making process. Notes that the three vary greatly in their readiness to use their personal authority in interpreting the audience's needs. Suggests that editors gain authority by assuming the role of language specialists and by…

Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4.

PubMed

Hosoda, Waki; Chianchiano, Peter; Griffin, James F; Pittman, Meredith E; Brosens, Lodewijk Aa; Noë, Michaël; Yu, Jun; Shindo, Koji; Suenaga, Masaya; Rezaee, Neda; Yonescu, Raluca; Ning, Yi; Albores-Saavedra, Jorge; Yoshizawa, Naohiko; Harada, Kenichi; Yoshizawa, Akihiko; Hanada, Keiji; Yonehara, Shuji; Shimizu, Michio; Uehara, Takeshi; Samra, Jaswinder S; Gill, Anthony J; Wolfgang, Christopher L; Goggins, Michael G; Hruban, Ralph H; Wood, Laura D

2017-05-01

High-grade pancreatic intraepithelial neoplasia (HG-PanIN) is the major precursor of pancreatic ductal adenocarcinoma (PDAC) and is an ideal target for early detection. To characterize pure HG-PanIN, we analysed 23 isolated HG-PanIN lesions occurring in the absence of PDAC. Whole-exome sequencing of five of these HG-PanIN lesions revealed a median of 33 somatic mutations per lesion, with a total of 318 mutated genes. Targeted next-generation sequencing of 17 HG-PanIN lesions identified KRAS mutations in 94% of the lesions. CDKN2A alterations occurred in six HG-PanIN lesions, and RNF43 alterations in five. Mutations in TP53, GNAS, ARID1A, PIK3CA, and TGFBR2 were limited to one or two HG-PanINs. No non-synonymous mutations in SMAD4 were detected. Immunohistochemistry for p53 and SMAD4 proteins in 18 HG-PanINs confirmed the paucity of alterations in these genes, with aberrant p53 labelling noted only in three lesions, two of which were found to be wild type in sequencing analyses. Sixteen adjacent LG-PanIN lesions from ten patients were also sequenced using targeted sequencing. LG-PanIN harboured KRAS mutations in 94% of the lesions; mutations in CDKN2A, TP53, and SMAD4 were not identified. These results suggest that inactivation of TP53 and SMAD4 are late genetic alterations, predominantly occurring in invasive PDAC. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Measurements of PANs during the New England Air Quality Study 2002

NASA Astrophysics Data System (ADS)

Roberts, J. M.; Marchewka, M.; Bertman, S. B.; Sommariva, R.; Warneke, C.; de Gouw, J.; Kuster, W.; Goldan, P.; Williams, E.; Lerner, B. M.; Murphy, P.; Fehsenfeld, F. C.

2007-10-01

Measurements of peroxycarboxylic nitric anhydrides (PANs) were made during the New England Air Quality Study 2002 cruise of the NOAA RV Ronald H Brown. The four compounds observed, PAN, peroxypropionic nitric anhydride (PPN), peroxymethacrylic nitric anhydride (MPAN), and peroxyisobutyric nitric anhydride (PiBN) were compared with results from other continental and Gulf of Maine sites. Systematic changes in PPN/PAN ratio, due to differential thermal decomposition rates, were related quantitatively to air mass aging. At least one early morning period was observed when O3 seemed to have been lost probably due to NO3 and N2O5 chemistry. The highest O3 episode was observed in the combined plume of isoprene sources and anthropogenic volatile organic compounds (VOCs) and NOx sources from the greater Boston area. A simple linear combination model showed that the organic precursors leading to elevated O3 were roughly half from the biogenic and half from anthropogenic VOC regimes. An explicit chemical box model confirmed that the chemistry in the Boston plume is well represented by the simple linear combination model. This degree of biogenic hydrocarbon involvement in the production of photochemical ozone has significant implications for air quality control strategies in this region.

Guidelines for Reviewers and the Editor at the Nuclear Safety Information Center.

ERIC Educational Resources Information Center

Whetsel, H. B.

The main purpose of this report is to help novice reviewers accelerate their apprenticeship at the Nuclear Safety Information Center, a computerized information service sponsored by the U.S. Atomic Energy Commission. Guidelines for reviewers are presented in Part 1; Part 2 contains guidelines for the novice editor. The goal of the reviewers and…

Performances of malaria P.f/Pan rapid test device Acon® (Pf HRP2/pan aldolase) and malaria Pf rapid test device Acon® (Pf HRP2) for the diagnosis of malaria in adults and children living in Gabon, Central Africa.

PubMed

Bouyou Akotet, Marielle Karine; Mawili-Mboumba, Denise Patricia; Madoungou, Blondel; Kombila, Maryvonne

2013-09-01

The Malaria Pf Rapid Test Device Acon® (Acon Labs) and the pan HRP2/aldolase RDT, Malaria P.f/Pan Rapid Test Device Acon® (Acon Labs), performances were evaluated for malaria species diagnosis in 592 febrile patients living in Gabon using microscopy as gold standard. Sensitivities were equal or above 96.0% for Plasmodium falciparum detection, of 62.5% for non-P. falciparum malaria species detection and higher in younger children (100%). Negative predictive values were greater than 97.0%. Acon®HRP2 had a higher specificity (96.6%) and lower false-positive (FP) rate (9.3%) compared to Acon®Pf/Pan, which had a specificity of 87.3% and a FP rate of 27.1% (P < 0.01). Overall, 32.5% of all Acon® Pf/Pan tests resulted in a "faint band" with only 2 resulted from samples with a parasitemia below 100 p/μL. The accuracy of Acon®HRP2 RDT for the diagnosis of P. falciparum infection is confirmed. However, the high FP rate observed with Acon®Pf/Pan is a limitation for its use. Copyright © 2013 Elsevier Inc. All rights reserved.

Population Screening Using Sewage Reveals Pan-Resistant Bacteria in Hospital and Community Samples.

PubMed

Meir-Gruber, Lital; Manor, Yossi; Gefen-Halevi, Shiraz; Hindiyeh, Musa Y; Mileguir, Fernando; Azar, Roberto; Smollan, Gill; Belausov, Natasha; Rahav, Galia; Shamiss, Ari; Mendelson, Ella; Keller, Nathan

2016-01-01

The presence of pan-resistant bacteria worldwide possesses a threat to global health. It is difficult to evaluate the extent of carriage of resistant bacteria in the population. Sewage sampling is a possible way to monitor populations. We evaluated the presence of pan-resistant bacteria in Israeli sewage collected from all over Israel, by modifying the pour plate method for heterotrophic plate count technique using commercial selective agar plates. This method enables convenient and fast sewage sampling and detection. We found that sewage in Israel contains multiple pan-resistant bacteria including carbapenemase resistant Enterobacteriacae carrying blaKPC and blaNDM-1, MRSA and VRE. blaKPC carrying Klebsiella pneumonia and Enterobacter cloacae were the most common Enterobacteriacae drug resistant bacteria found in the sewage locations we sampled. Klebsiella pneumonia, Enterobacter spp., Escherichia coli and Citrobacter spp. were the 4 main CRE isolated from Israeli sewage and also from clinical samples in our clinical microbiology laboratory. Hospitals and Community sewage had similar percentage of positive samplings for blaKPC and blaNDM-1. VRE was found to be more abundant in sewage in Israel than MRSA but there were more locations positive for MRSA and VRE bacteria in Hospital sewage than in the Community. Therefore, our upgrade of the pour plate method for heterotrophic plate count technique using commercial selective agar plates can be a useful tool for routine screening and monitoring of the population for pan-resistant bacteria using sewage.

Population Screening Using Sewage Reveals Pan-Resistant Bacteria in Hospital and Community Samples

PubMed Central

Mileguir, Fernando; Azar, Roberto; Smollan, Gill; Belausov, Natasha; Rahav, Galia; Shamiss, Ari; Mendelson, Ella; Keller, Nathan

2016-01-01

The presence of pan-resistant bacteria worldwide possesses a threat to global health. It is difficult to evaluate the extent of carriage of resistant bacteria in the population. Sewage sampling is a possible way to monitor populations. We evaluated the presence of pan-resistant bacteria in Israeli sewage collected from all over Israel, by modifying the pour plate method for heterotrophic plate count technique using commercial selective agar plates. This method enables convenient and fast sewage sampling and detection. We found that sewage in Israel contains multiple pan-resistant bacteria including carbapenemase resistant Enterobacteriacae carrying blaKPC and blaNDM-1, MRSA and VRE. blaKPC carrying Klebsiella pneumonia and Enterobacter cloacae were the most common Enterobacteriacae drug resistant bacteria found in the sewage locations we sampled. Klebsiella pneumonia, Enterobacter spp., Escherichia coli and Citrobacter spp. were the 4 main CRE isolated from Israeli sewage and also from clinical samples in our clinical microbiology laboratory. Hospitals and Community sewage had similar percentage of positive samplings for blaKPC and blaNDM-1. VRE was found to be more abundant in sewage in Israel than MRSA but there were more locations positive for MRSA and VRE bacteria in Hospital sewage than in the Community. Therefore, our upgrade of the pour plate method for heterotrophic plate count technique using commercial selective agar plates can be a useful tool for routine screening and monitoring of the population for pan-resistant bacteria using sewage. PMID:27780222

Osteological histology of the Pan-Alcidae (Aves, Charadriiformes): correlates of wing-propelled diving and flightlessness.

PubMed

Smith, N Adam; Clarke, Julia A

2014-02-01

Although studies of osteological morphology, gross myology, myological histology, neuroanatomy, and wing-scaling have all documented anatomical modifications associated with wing-propelled diving, the osteohistological study of this highly derived method of locomotion has been limited to penguins. Herein we present the first osteohistological study of the derived forelimbs and hind limbs of wing-propelled diving Pan-Alcidae (Aves, Charadriiformes). In addition to detailing differences between wing-propelled diving charadriiforms and nondiving charadriiforms, microstructural modifications to the humeri, ulnae and femora of extinct flightless pan-alcids are contrasted with those of volant alcids. Histological thin-sections of four species of pan-alcids (Alca torda, †Alca grandis, †Pinguinus impennis, †Mancalla cedrosensis) and one outgroup charadriiform (Stercorarius longicaudus) were compared. The forelimb bones of wing-propelled diving charadriiforms were found to have significantly thicker (∼22%) cortical bone walls. Additionally, as in penguins, the forelimbs of flightless pan-alcids are found to be osteosclerotic. However, unlike the pattern documented in penguins that display thickened cortices in both forelimbs and hind limbs, the forelimb and hind limb elements of pan-alcids display contrasting microstructural morphologies with thickened forelimb cortices and relatively thinner femoral cortices. Additionally, the identification of medullary bone in the sampled †Pinguinus impennis specimen suggests that further osteohistological investigation could provide an answer to longstanding questions regarding sexual dimorphism of Great Auks. Finally, these results suggest that it is possible to discern volant from flightless wing-propelled divers from fragmentary fossil remains. Copyright © 2013 Wiley Periodicals, Inc.

Semi-automated XML markup of biosystematic legacy literature with the GoldenGATE editor.

PubMed

Sautter, Guido; Böhm, Klemens; Agosti, Donat

2007-01-01

Today, digitization of legacy literature is a big issue. This also applies to the domain of biosystematics, where this process has just started. Digitized biosystematics literature requires a very precise and fine grained markup in order to be useful for detailed search, data linkage and mining. However, manual markup on sentence level and below is cumbersome and time consuming. In this paper, we present and evaluate the GoldenGATE editor, which is designed for the special needs of marking up OCR output with XML. It is built in order to support the user in this process as far as possible: Its functionality ranges from easy, intuitive tagging through markup conversion to dynamic binding of configurable plug-ins provided by third parties. Our evaluation shows that marking up an OCR document using GoldenGATE is three to four times faster than with an off-the-shelf XML editor like XML-Spy. Using domain-specific NLP-based plug-ins, these numbers are even higher.

Molecular principles behind pyrazinamide resistance due to mutations in panD gene in Mycobacterium tuberculosis.

PubMed

Pandey, Bharati; Grover, Sonam; Tyagi, Chetna; Goyal, Sukriti; Jamal, Salma; Singh, Aditi; Kaur, Jagdeep; Grover, Abhinav

2016-04-25

The latest resurrection of drug resistance poses serious threat to the treatment and control of the disease. Mutations have been detected in panD gene in the Mycobacterium tuberculosis (Mtb) strains. Mutation of histidine to arginine at residue 21 (H21R) and isoleucine to valine at residue 29 (I49V) in the non-active site of panD gene has led to PZA resistance. This study will help in reconnoitering the mechanism of pyrazinamide (PZA) resistance caused due to double mutation identified in the panD gene of M. tuberculosis clinical isolates. It is known that panD gene encodes aspartate decarboxylase essential for β-alanine synthesis that makes it a potential therapeutic drug target for tuberculosis treatment. The knowledge about the molecular mechanism conferring drug resistance in M. tuberculosis is scarce, which is a significant challenge in designing successful therapeutic drug. In this study, structural and dynamic repercussions of H21R-I49V double mutation in panD complexed with PZA have been corroborated through docking and molecular dynamics based simulation. The double mutant (DM) shows low docking score and thus, low binding affinity for PZA as compared to the native protein. It was observed that the mutant protein exhibits more structural fluctuation at the ligand binding site in comparison to the native type. Furthermore, the flexibility and compactness analyses indicate that the double mutation influence interaction of PZA with the protein. The hydrogen-bond interaction patterns further supported our results. The covariance and PCA analysis elucidated that the double mutation affects the collective motion of residues in phase space. The results have been presented with an explanation for the induced drug resistance conferred by the H21R-I49V double mutation in panD gene and gain valuable insight to facilitate the advent of efficient therapeutics for combating resistance against PZA. Copyright © 2016 Elsevier B.V. All rights reserved.

Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure.

PubMed

Gordon, Sean P; Contreras-Moreira, Bruno; Woods, Daniel P; Des Marais, David L; Burgess, Diane; Shu, Shengqiang; Stritt, Christoph; Roulin, Anne C; Schackwitz, Wendy; Tyler, Ludmila; Martin, Joel; Lipzen, Anna; Dochy, Niklas; Phillips, Jeremy; Barry, Kerrie; Geuten, Koen; Budak, Hikmet; Juenger, Thomas E; Amasino, Richard; Caicedo, Ana L; Goodstein, David; Davidson, Patrick; Mur, Luis A J; Figueroa, Melania; Freeling, Michael; Catalan, Pilar; Vogel, John P

2017-12-19

While prokaryotic pan-genomes have been shown to contain many more genes than any individual organism, the prevalence and functional significance of differentially present genes in eukaryotes remains poorly understood. Whole-genome de novo assembly and annotation of 54 lines of the grass Brachypodium distachyon yield a pan-genome containing nearly twice the number of genes found in any individual genome. Genes present in all lines are enriched for essential biological functions, while genes present in only some lines are enriched for conditionally beneficial functions (e.g., defense and development), display faster evolutionary rates, lie closer to transposable elements and are less likely to be syntenic with orthologous genes in other grasses. Our data suggest that differentially present genes contribute substantially to phenotypic variation within a eukaryote species, these genes have a major influence in population genetics, and transposable elements play a key role in pan-genome evolution.

Integration Of PanDA Workload Management System With Supercomputers for ATLAS and Data Intensive Science

DOE Office of Scientific and Technical Information (OSTI.GOV)

De, K; Jha, S; Klimentov, A

2016-01-01

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Managementmore » System for managing the workflow for all data processing on over 150 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 250,000 cores with a peak performance of 0.3 petaFLOPS, LHC data taking runs require more resources than Grid computing can possibly provide. To alleviate these challenges, LHC experiments are engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with supercomputers in United States, Europe and Russia (in particular with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF), MIRA supercomputer at Argonne Leadership Computing Facilities (ALCF), Supercomputer at the National Research Center Kurchatov Institute , IT4 in Ostrava and others). Current approach utilizes modified PanDA pilot framework for job submission to the supercomputers batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on LCFs multi-core worker nodes. This

The limits of endowment effects in great apes (Pan paniscus, Pan troglodytes, Gorilla gorilla, Pongo pygmaeus).

PubMed

Kanngiesser, Patricia; Santos, Laurie R; Hood, Bruce M; Call, Josep

2011-11-01

The endowment effect describes the bias that people often value things that they possess more than things they do not possess. Thus, they are often reluctant to trade items in their possession for items of equivalent value. Some nonhuman primates appear to share this bias with humans, but it remains an open question whether they show endowment effects to the same extent as humans do. We investigated endowment effects in all four great ape species (Pan paniscus, Pan troglodytes, Gorilla gorilla, Pongo pygmaeus) by varying whether apes were endowed with food items (Experiment 1, N = 22) or tools that were instrumental in retrieving food (Experiment 2, N = 23). We first assessed apes' preferences for items of a pair and their willingness to trade items in their possession. We then endowed apes with one item of a pair and offered them to trade for the other item. Apes showed endowment effects for food, but not for tools. In Experiment 3, we endowed bonobos (N = 4) and orangutans (N = 5) with either one or 12 food items. Endowment effects did not differ between species and were not influenced by the number of endowed food items. Our findings suggest that endowment effects in great apes are restricted to immediate food gratification and remain unaffected by the quantity of food rewards. However, endowment effects do not seem to extend to other, nonconsumable possessions even when they are instrumental in retrieving food. In general, apes do not show endowment effects across a range of different commodities as humans typically do.

Fabrication of novel chitosan/PAN/magnetic ZSM-5 zeolite coated sponges for absorption of oil from water surfaces.

PubMed

Samadi, Saman; Yazd, Shabnam Sharif; Abdoli, Hossein; Jafari, Pooya; Aliabadi, Majid

2017-12-01

In the present study, the chitosan (bottom layer)/polyacrylonitrile (top layer, PAN) nanofibers were coated on the sponge surface. The synthesized magnetic Fe 3 O 4 - ZSM-5 nanozeolites have been loaded into the chitosan/PAN nanofibers to increase the performance of nanofibers toward absorption of lubricating oil, motor oil and pump oil from water surfaces. Scanning electron microscope (SEM), Transmission electron microscope (TEM) and X-ray diffraction (XRD) analysis were used to characterize the synthesized nanozeolites. The morphology and wettability of nanofibers were determined using SEM and water contact angle tests. The influence of Fe 3 O 4 - ZSM-5 nanozeolite content and chitosan/PAN/Fe 3 O 4 - ZSM-5 nanofiber thickness was evaluated on the potential of sponges for oils absorption. The maximum capacity of the chitosan/PAN/Fe 3 O 4 - ZSM-5 nanofibers coated sponges for absorption of motor oil, lubricating oil and pump oil was found to be 99.4, 95.3 and 88.1g/g, in Fe 3 O 4 - ZSM-5 2wt.% and nanofiber thickness of 12μm (chitosan layer of 2μm and PAN layer of 10μm). The reusability of nanofibrous sponges showed that the hydrophobic chitosan/PAN/Fe 3 O 4 - ZSM-5 nanofibers coated sponges can be easily reused in water-oil separation for many cycles. Copyright © 2017 Elsevier B.V. All rights reserved.

Pan-derived isotopic composition of atmospheric vapour in a Mediterranean wetland (Rhône River Delta, France).

PubMed

Vallet-Coulomb, Christine; Cartapanis, Olivier; Radakovitch, Olivier; Sonzogni, Corinne; Pichaud, Marc

2010-03-01

A continuous record of atmospheric vapour isotopic composition (delta(A)) can be derived from the isotope mass balance of a water body submitted to natural evaporation. In this paper, we present preliminary results of the application of this method to a drying evaporation pan, located in a Mediterranean wetland, during a two-month summer period. Results seem consistent with few atmospheric vapour data based on the assumption of isotopic equilibrium with precipitation, but we observed a shift between pan-derived delta(A) and the composition of vapour samples collected by cold trapping. These results suggest that further investigations are necessary to evaluate the effect of diurnal variations of atmospheric conditions on the applicability of the pan-evaporation method, and on the representative of grab atmospheric samples. We also propose a sensitivity analysis for evaluating the impact of the different measured components on delta(A) calculation, and show an improvement in the method efficiency as the pan is drying.

Editorial: Conflict of interest policy for Editors of The American Journal of Clinical Nutrition

USDA-ARS?s Scientific Manuscript database

Integrity in the publication process requires impartiality at all levels of review. The American Journal of Clinical Nutrition (AJCN) adheres to the policy of the International Committee of Medical Journal Editors (ICMJE), Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writin...

Editors' message--Hydrogeology Journal in 2003

USGS Publications Warehouse

Voss, Clifford; Olcott, Perry; Schneider, Robert

2004-01-01

Hydrogeology Journal appeared in six issues containing a total of 710 pages and 48 major articles, including 31 Papers and 14 Reports, as well as some Technical Notes and Book Reviews. The number of submitted manuscripts continues to increase. The final issue of 2003 also contained the annual volume index. Hydrogeology Journal (HJ) is an international forum for hydrogeology and related disciplines and authors in 2003 were from about 28 countries. Articles advanced hydrogeologic science and described hydrogeologic systems in many regions worldwide. These articles focused on a variety of general topics and on studies of hydrogeology in 24 countries: Afghanistan, Algeria, Argentina, Australia, Bangladesh, Belgium, Canada, Chile, China, Denmark, France, India, Italy, Mexico, Netherlands, New Zealand, Nigeria, Norway, Portugal, Russia, South Africa, Switzerland, Turkey, and U.S.A. The Guest Editor of the 2003 HJ theme issue on “Hydromechanics in Geology and Geotechnics”, Ove Stephansson, assembled a valuable collection of technical reviews and research papers from eminent authors on important aspects of the subject area.

NaF-loaded core-shell PAN-PMMA nanofibers as reinforcements for Bis-GMA/TEGDMA restorative resins.

PubMed

Cheng, Liyuan; Zhou, Xuegang; Zhong, Hong; Deng, Xuliang; Cai, Qing; Yang, Xiaoping

2014-01-01

A kind of core-shell nanofibers containing sodium fluoride (NaF) was produced and used as reinforcing materials for dimethacrylate-based dental restorative resins in this study. The core-shell nanofibers were prepared by coaxial-electrospinning with polyacrylonitrile (PAN) and poly(methyl methacrylate) (PMMA) solutions as core and shell fluids, respectively. The produced PAN-PMMA nanofibers varied in fiber diameter and the thickness of PMMA shell depending on electrospinning parameters. NaF-loaded nanofibers were obtained by incorporating NaF nanocrystals into the core fluid at two loadings (0.8 or 1.0wt.%). Embedment of NaF nanocrystals into the PAN core did not damage the core-shell structure. The addition of PAN-PMMA nanofibers into Bis-GMA/TEGDMA clearly showed the reinforcement due to the good interfacial adhesion between fibers and resin. The flexural strength (Fs) and flexural modulus (Ey) of the composites decreased slightly as the thickness of PMMA shell increasing. Sustained fluoride releases with minor initial burst release were achieved from NaF-loaded core-shell nanofibers and the corresponding composites, which was quite different from the case of embedding NaF nanocrystals into the dental resin directly. The study demonstrated that NaF-loaded PAN-PMMA core-shell nanofibers were not only able to improve the mechanical properties of restorative resin, but also able to provide sustained fluoride release to help in preventing secondary caries. © 2013.

Palaeoamyda messeliana nov. comb. (Testudines, Pan-Trionychidae) from the Eocene Messel Pit and Geiseltal localities, Germany, taxonomic and phylogenetic insights.

PubMed

Cadena, Edwin

2016-01-01

Abundant pan-trionychid (soft-shell) turtles specimens have been found in Eocene sequences of central Europe, particularly from two localities in Germany, the Messel Pit (a UNESCO World Natural Heritage Site) and Geiseltal, traditionally attributed to Trionyx messelianus or Rafetoides austriacus . Over the last two decades new specimens of this taxon from these two localities have been discovered and fully prepared. However, they have remained unstudied, as well as their phylogenetic position inside Pan-Trionychidae is unknown. Five new specimens of Palaeoamyda messeliana nov. comb. from Messel Pit and Geiseltal localities are fully described here. A revised diagnosis for the species is also presented here, together with its inclusion in a phylogenetic analysis of Pan-Trionychidae that shows that this species is sister to the extant Amyda cartilaginea , one of the most abundant pan-trionychid (soft-shell) turtles from Asia, both members of the clade Chitrini. The specimens described in here are among the best and most complete fossil pan-trionychid skeletons so far known.

Shape of the orbital opening: individual characterization and analysis of variability in modern humans, Gorilla gorilla, and Pan troglodytes.

PubMed

Schmittbuhl, M; Le Minor, J M; Allenbach, B; Schaaf, A

1999-05-01

The description of the human orbital shape is principally qualitative in the classical literature, and characterised by adjectives such as circular, rectangular or quadrangular. In order to provide a precise quantification and interpretation of this shape, a study based on automatic image analysis and Fourier analysis was carried out on 45 human skulls (30 males, 15 females), and for comparison on 61 skulls of Gorilla gorilla (40 males, 21 females), and 34 skulls of Pan troglodytes (20 males, 14 females). Sexual dimorphism in the shape of the orbital opening was not demonstrated. Its dominant morphological features could be characterized by Fourier analysis; elliptical elongation and quadrangularity were dominant morphological features of the shape of the orbital opening in the three species. Elliptical elongation was more marked in humans and Pan, whereas quadrangularity was particularly emphasized in Gorilla. An intraspecific variability of the shape of the orbital opening existed in humans, Gorilla and Pan, and seemed close in the three species. Interspecific partition between humans, Gorilla and Pan was demonstrated despite the variability observed in the three species studied. Interspecific differences between Gorilla and the Pan-humans group were principally explained by the differences in quadrangularity, and by differences in orientation of triangularity and pentagonality. Differences in the shape of the orbital opening between humans and Pan were principally explained by differences in hexagonality, and by differences in orientation of quadrangularity. A closeness of shape between some humans and some individuals in Pan and, to a lesser degree, with some individuals in Gorilla was observed, demonstrating the existence of a morphological continuum of the shape of the orbital opening in hominoids.

Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure

DOE PAGES

Gordon, Sean P.; Contreras-Moreira, Bruno; Woods, Daniel P.; ...

2017-12-19

While prokaryotic pan-genomes have been shown to contain many more genes than any individual organism, the prevalence and functional significance of differentially present genes in eukaryotes remains poorly understood. Whole-genome de novo assembly and annotation of 54 lines of the grass Brachypodium distachyon yield a pan-genome containing nearly twice the number of genes found in any individual genome. Genes present in all lines are enriched for essential biological functions, while genes present in only some lines are enriched for conditionally beneficial functions (e.g., defense and development), display faster evolutionary rates, lie closer to transposable elements and are less likely tomore » be syntenic with orthologous genes in other grasses. Our data suggest that differentially present genes contribute substantially to phenotypic variation within a eukaryote species, these genes have a major influence in population genetics, and transposable elements play a key role in pan-genome evolution.« less

Piggy: a rapid, large-scale pan-genome analysis tool for intergenic regions in bacteria.

PubMed

Thorpe, Harry A; Bayliss, Sion C; Sheppard, Samuel K; Feil, Edward J

2018-04-01

The concept of the "pan-genome," which refers to the total complement of genes within a given sample or species, is well established in bacterial genomics. Rapid and scalable pipelines are available for managing and interpreting pan-genomes from large batches of annotated assemblies. However, despite overwhelming evidence that variation in intergenic regions in bacteria can directly influence phenotypes, most current approaches for analyzing pan-genomes focus exclusively on protein-coding sequences. To address this we present Piggy, a novel pipeline that emulates Roary except that it is based only on intergenic regions. A key utility provided by Piggy is the detection of highly divergent ("switched") intergenic regions (IGRs) upstream of genes. We demonstrate the use of Piggy on large datasets of clinically important lineages of Staphylococcus aureus and Escherichia coli. For S. aureus, we show that highly divergent (switched) IGRs are associated with differences in gene expression and we establish a multilocus reference database of IGR alleles (igMLST; implemented in BIGSdb).

Extensive gene content variation in the Brachypodium distachyon pan-genome correlates with population structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gordon, Sean P.; Contreras-Moreira, Bruno; Woods, Daniel P.

While prokaryotic pan-genomes have been shown to contain many more genes than any individual organism, the prevalence and functional significance of differentially present genes in eukaryotes remains poorly understood. Whole-genome de novo assembly and annotation of 54 lines of the grass Brachypodium distachyon yield a pan-genome containing nearly twice the number of genes found in any individual genome. Genes present in all lines are enriched for essential biological functions, while genes present in only some lines are enriched for conditionally beneficial functions (e.g., defense and development), display faster evolutionary rates, lie closer to transposable elements and are less likely tomore » be syntenic with orthologous genes in other grasses. Our data suggest that differentially present genes contribute substantially to phenotypic variation within a eukaryote species, these genes have a major influence in population genetics, and transposable elements play a key role in pan-genome evolution.« less

Esthetic or Functional, Saccharine or Shocking? An Editor Looks at Values in Children's Books.

ERIC Educational Resources Information Center

Giblin, James Cross

1977-01-01

Discusses artistic or esthetic, social and cultural, functional, and commercial values looked for by children's book editors in selecting and publishing manuscripts. Also reviews changes in social and cultural values as shown by children's books published in 1947, 1957, and 1967. (GT)

What Does It Take to Change an Editor's Mind? Identifying Minimally Important Difference Thresholds for Peer Reviewer Rating Scores of Scientific Articles.

PubMed

Callaham, Michael; John, Leslie K

2018-01-05

We define a minimally important difference for the Likert-type scores frequently used in scientific peer review (similar to existing minimally important differences for scores in clinical medicine). The magnitude of score change required to change editorial decisions has not been studied, to our knowledge. Experienced editors at a journal in the top 6% by impact factor were asked how large a change of rating in "overall desirability for publication" was required to trigger a change in their initial decision on an article. Minimally important differences were assessed twice for each editor: once assessing the rating change required to shift the editor away from an initial decision to accept, and the other assessing the magnitude required to shift away from an initial rejection decision. Forty-one editors completed the survey (89% response rate). In the acceptance frame, the median minimally important difference was 0.4 points on a scale of 1 to 5. Editors required a greater rating change to shift from an initial rejection decision; in the rejection frame, the median minimally important difference was 1.2 points. Within each frame, there was considerable heterogeneity: in the acceptance frame, 38% of editors did not change their decision within the maximum available range; in the rejection frame, 51% did not. To our knowledge, this is the first study to determine the minimally important difference for Likert-type ratings of research article quality, or in fact any nonclinical scientific assessment variable. Our findings may be useful for future research assessing whether changes to the peer review process produce clinically meaningful differences in editorial decisionmaking. Copyright © 2017 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

An ab initio molecular orbital study of the mechanism for the gas-phase water-mediated decomposition and the formation of hydrates of peroxyacetyl nitrate (PAN).

PubMed

Li, Yumin; Francisco, Joseph S

2005-08-31

There is uncertainty in the mechanism for the hydrolysis of peroxyacetyl nitrate (PAN), and experimental attempts to detect products of the direct reaction have been unsuccessful. Ab initio calculations are used to examine the energetics of water-mediated decomposition of gas-phase PAN into acetic acid and peroxynitric acid. On the basis of ab initio calculations, an alternative reaction mechanism for the decomposition of PAN is proposed. The calculations indicate that the barrier for one water addition to PAN is large. However, including additional water molecules reveals a substantially lower energy route. The calculations suggest that the formation of PAN hydrate complexes are energetically favorable and stable. Additional waters are increasingly efficient at stabilizing hydrated PAN.

Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary.

PubMed

Brynildsrud, Ola; Bohlin, Jon; Scheffer, Lonneke; Eldholm, Vegard

2016-11-25

Genome-wide association studies (GWAS) have become indispensable in human medicine and genomics, but very few have been carried out on bacteria. Here we introduce Scoary, an ultra-fast, easy-to-use, and widely applicable software tool that scores the components of the pan-genome for associations to observed phenotypic traits while accounting for population stratification, with minimal assumptions about evolutionary processes. We call our approach pan-GWAS to distinguish it from traditional, single nucleotide polymorphism (SNP)-based GWAS. Scoary is implemented in Python and is available under an open source GPLv3 license at https://github.com/AdmiralenOla/Scoary .

EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Gardner, Jason S.

2012-01-01

As I begin my tenure as Editor-in-Chief of Journal of Physics: Condensed Matter (JPCM), I look upon this opportunity as both an honour and a real challenge. The journal is in great shape thanks to the work of my predecessors, Marshall Stoneham and David Ferry. The journal's solid reputation is based largely on the work these gentlemen have done over the past decade. The other main reason for the success of JPCM is the amazing staff in Bristol; keep up the good work, please. When discussing the journal with scientists from all corners of the globe, one thing is always mentioned—JPCM is a very reliable journal with well-written, high-quality papers, and a fast but rigorous peer-review process that provides fair, detailed and constructive referee reports for the benefit of authors. This is due almost entirely to our great authors and referees; we rely on them every day—thank you. As the new Editor-in-Chief I hope to continue to improve still further the journal's status in condensed matter science. As mentioned above, our reputation is excellent, but the reality is that we live in a world of bibliometrics and rankings. Over the past few years JPCM has been repositioned as a journal at the forefront of condensed matter physics, and the impact of the journal should increase further as a result of continued emphasis on commissioning in cutting-edge areas identified by the Editorial Board and the journal team. In addition to regular papers, JPCM has a number of other content streams that authors and readers can benefit from. Fast track communications (FTCs) offer exceptionally fast publication for work of the highest impact and urgency. By their select nature, FTCs benefit from personal treatment by the Editorial Board and the average receipt-to-first-decision time is just 11 days (the average receipt-to-publication time is just 45 days). Topical reviews in JPCM make the journal one of the most authoritative sources of review content for condensed matter physics

Mapping the groundwater vulnerability for pollution at the pan African scale.

PubMed

Ouedraogo, Issoufou; Defourny, Pierre; Vanclooster, Marnik

2016-02-15

We estimated vulnerability and pollution risk of groundwater at the pan-African scale. We therefore compiled the most recent continental scale information on soil, land use, geology, hydrogeology and climate in a Geographical Information System (GIS) at a resolution of 15 km × 15 km and at the scale of 1:60,000,000. The groundwater vulnerability map was constructed by means of the DRASTIC method. The map reveals that groundwater is highly vulnerable in Central and West Africa, where the watertable is very low. In addition, very low vulnerability is found in the large sedimentary basins of the African deserts where groundwater is situated in very deep aquifers. The groundwater pollution risk map is obtained by overlaying the DRASTIC vulnerability map with land use. The northern, central and western part of the African continent is dominated by high pollution risk classes and this is very strongly related to shallow groundwater systems and the development of agricultural activities. Subsequently, we performed a sensitivity analysis to evaluate the relative importance of each parameter on groundwater vulnerability and pollution risk. The sensitivity analysis indicated that the removal of the impact of vadose zone, the depth of the groundwater, the hydraulic conductivity and the net recharge causes a large variation in the mapped vulnerability and pollution risk. The mapping model was validated using nitrate concentration data of groundwater as a proxy of pollution risk. Pan-African concentration data were inferred from a meta-analysis of literature data. Results shows a good match between nitrate concentration and the groundwater pollution risk classes. The pan African assessment of groundwater vulnerability and pollution risk is expected to be of particular value for water policy and for designing groundwater resources management programs. We expect, however, that this assessment can be strongly improved when better pan African monitoring data related to groundwater

Common statistical and research design problems in manuscripts submitted to high-impact psychiatry journals: what editors and reviewers want authors to know.

PubMed

Harris, Alex H S; Reeder, Rachelle; Hyun, Jenny K

2009-10-01

Journal editors and statistical reviewers are often in the difficult position of catching serious problems in submitted manuscripts after the research is conducted and data have been analyzed. We sought to learn from editors and reviewers of major psychiatry journals what common statistical and design problems they most often find in submitted manuscripts and what they wished to communicate to authors regarding these issues. Our primary goal was to facilitate communication between journal editors/reviewers and researchers/authors and thereby improve the scientific and statistical quality of research and submitted manuscripts. Editors and statistical reviewers of 54 high-impact psychiatry journals were surveyed to learn what statistical or design problems they encounter most often in submitted manuscripts. Respondents completed the survey online. The authors analyzed survey text responses using content analysis procedures to identify major themes related to commonly encountered statistical or research design problems. Editors and reviewers (n=15) who handle manuscripts from 39 different high-impact psychiatry journals responded to the survey. The most commonly cited problems regarded failure to map statistical models onto research questions, improper handling of missing data, not controlling for multiple comparisons, not understanding the difference between equivalence and difference trials, and poor controls in quasi-experimental designs. The scientific quality of psychiatry research and submitted reports could be greatly improved if researchers became sensitive to, or sought consultation on frequently encountered methodological and analytic issues.

Public Release of Pan-STARRS Data

NASA Astrophysics Data System (ADS)

Flewelling, Heather; Consortium, panstarrs

2015-08-01

Pan-STARRS 1 is a 1.8 meter survey telescope, located on Haleakala, Hawaii, with a 1.4 Gigapixel camera, a 7 square degree field of view, and 5 filters (g,r,i,z,y). The public release of data, which is available to everyone, consists of 4 years of data taken between May 2010 and April 2014. Two of the surveys available in the public release are the 3pi survey and the Medium Deep (MD) survey. The 3pi survey has roughly 60 epochs (12 per filter) covering 3/4 of the sky and everything north of -30 degrees declination. The MD survey consists of 10 fields, observed in a couple of filters each night, usually 8 exposures per filter per field, for about 4000 epochs per MD field. The available data product are accessed through the “Postage Stamp Server” and through the Published Science Products Subsystem (PSPS), both of these are available through the Pan-STARRS Science Interface (PSI). The Postage Stamp Server provides images and catalogs for different stages of processing on single exposures, stack images, difference images, and forced photometry. The PSPS is a SQLServer database that can be queried via script or web interface, with a database for each MD field and a large database for the 3pi survey. This database has relative photometry and astrometry and object associations, making it easy to do searches across the entire sky as well as tools to generate lightcurves of individual objects as a function of time.

Interview with the editor: David L. Turpin by Robert P. Scholz.

PubMed

Turpin, David L

2010-04-01

David L. Turpin has worked on dental journals for over 30 years--from his early days on the Pacific Coast Society of Orthodontists Bulletin, to the Angle Orthodontist, and to the American Journal of Orthodontics and Dentofacial Orthopedics. He will retire as editor-in-chief of the American Journal of Orthodontics and Dentofacial Orthopedics at the end of 2010. Copyright (c) 2010 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

The PanCam instrument on the 2018 Exomars rover: Scientific objectives

NASA Astrophysics Data System (ADS)

Jaumann, Ralf; Coates, Andrew; Hauber, Ernst; Hoffmann, Harald; Schmitz, Nicole; Le Deit, Laetitia; Tirsch, Daniela; Paar, Gerhard; Griffiths, Andrew

2010-05-01

The Exomars Panoramic Camera System is an imaging suite of three camera heads to be mounted on the ExoMars rover`s mast, with the boresight 1.8 m above ground. As late as the ExoMars Pasteur Payload Design Review (PDR) in 2009, the PanCam consists of two identical wide angle cameras (WAC) with fixed focal length lenses, and a high resolution camera (HRC) with an automatic focus mechanism, placed adjacent to the right WAC. The WAC stereo pair provides binocular vision for stereoscopic studies as well as 12 filter positions (per camera) for stereoscopic colour imaging and scientific multispectral studies. The stereo baseline of the pair is 500 mm. The two WAC have 22 mm focal length, f/10 lenses that illuminate detectors with 1024 × 1024 pixels. WAC lenses are fixed, with an optimal focus set to 4 m, and a focus ranging from 1.2 m (corresponding to the nearest view of the calibration target on the rover deck) to infinity. The HRC is able to focus between 0.9 m (distance to a drill core on the rover`s sample tray) and infinity. The instantaneous field of views of WAC and HRC are 580 μrad/pixel and 83 μrad/pixel, respectively. The corresponding resolution (in mm/pixel) at a distance of 2 m are 1.2 (WAC) and 0.17 (HRC), at 100 m distance it is 58 (WAC) and 8.3 (HRC). WAC and HRC will be geometrically co-aligned. The main scientific goal of PanCam is the geologic characterisation of the environment in which the rover is operating, providing the context for investigations carried out by the other instruments of the Pasteur payload. PanCam data will serve as a bridge between orbital data (high-resolution images from HRSC, CTX, and HiRISE, and spectrometer data from OMEGA and CRISM) and the data acquired in situ on the Martian surface. The position of HRC on top of the rover`s mast enables the detailed panoramic inspection of surface features over the full horizontal range of 360° even at large distances, an important prerequisite to identify the scientifically most

Martin Stutzmann: Editor, Teacher, Scientist and Friend

NASA Astrophysics Data System (ADS)

Cardona, Manuel

2005-03-01

On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

Tracking the displacement of objects: a series of tasks with great apes (Pan troglodytes, Pan paniscus, Gorilla gorilla, and Pongo pygmaeus) and young children (Homo sapiens).

PubMed

Barth, Jochen; Call, Josep

2006-07-01

The authors administered a series of object displacement tasks to 24 great apes and 24 30-month-old children (Homo sapiens). Objects were placed under 1 or 2 of 3 cups by visible or invisible displacements. The series included 6 tasks: delayed response, inhibition test, A not B, rotations, transpositions, and object permanence. Apes and children solved most tasks performing at comparable levels except in the transposition task, in which apes performed better than children. Ape species performed at comparable levels in all tasks except in single transpositions, in which chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) performed better than gorillas (Gorilla gorilla) and orangutans (Pongo pygmeaus). All species found nonadjacent trials and rotations especially difficult. The number of elements that changed locations, the type of displacement, and having to inhibit predominant reaching responses were factors that negatively affected the subjects' performance.

In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery.

PubMed

Khoshkholgh-Sima, Baharak; Sardari, Soroush; Izadi Mobarakeh, Jalal; Khavari-Nejad, Ramezan Ali

2015-01-01

Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of noncompliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need to develop novel antitubercular medicines that target new or more effective biochemical pathways to prevent drug resistant Mycobacterium. Integrated study of metabolic pathways through in-silico approach played a key role in antimycobacterial design process in this study. Our results suggest that pantothenate synthetase (PanC), anthranilate phosphoribosyl transferase (TrpD) and 3-isopropylmalate dehydratase (LeuD) might be appropriate drug targets. In the next step, in-silico ligand analysis was used for more detailed study of chemical tractability of targets. This was helpful to identify pantothenate synthetase (PanC, Rv3602c) as the best target for antimycobacterial design procedure. Virtual library screening on the best ligand of PanC was then performed for inhibitory ligand design. At the end, five chemical intermediates showed significant inhibition of Mycobacterium bovis with good selectivity indices (SI) ≥10 according to Tuberculosis Antimicrobial Acquisition & Coordinating Facility of US criteria for antimycobacterial screening programs.

The Pan-American Federation of Neurological Societies (PAFNS): A New Regional Organization.

PubMed

Medina, Marco T; Román, Gustavo C

2016-07-15

The Pan-American Federation of Neurological Societies (PAFNS) was created on 15 November 2011 during the 20th World Congress of Neurology in Marrakech by virtue of the "Declaration of Morocco" signed by the WFN Latin American delegates and ratified on 5 March 2012 by delegates attending the 13th Pan-American Congress of Neurology in La Paz, Bolivia. On 20 March 2013 delegates attending the 65th Annual Meeting of the American Academy of Neurology in San Diego, California, USA, gave formal approval to the PAFNS Constitution. The neurological societies from the following countries have approved and signed the constitution as founding members and active ordinary members: Argentina, Brazil, Bolivia, Chile, Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Uruguay, and Venezuela. The Ibero-American Stroke Society (SIECV), the Commission on Latin American Affairs of the International League Against Epilepsy (ILAE) and the World Sleep Society have requested the status of Associate Members. The WFN and the American Academy of Neurology provided seed grants for the creation of the Pan-American Federation of Neurological Societies. PAFNS represents a major step for the improvement of regional neurological care, education and research. Copyright © 2016 Elsevier B.V. All rights reserved.

Comments on ``Anonymous Reviews'' An Editor's View of Anonymous Reviews

NASA Astrophysics Data System (ADS)

Goff, John A.

I have read with great interest the recent Forum commentaries in Eos by Myrl Beck, Charles Robinove, Robert Criss, and Anne Hofmeister regarding anonymous reviews. I heartily support their position that anonymous reviews should be avoided. I have not written an anonymous review in ages (and regret the few that I did), and have always appreciated and respected greatly anyone who signs a critical review of one of my own papers. However, I would like to add some perspective from the editorial standpoint. I have served as JGR associate editor for 3 years (never anonymously!), and as Eos editor for seismology and tectonophysics for 4. Over the years, I have rejected a fair number of papers, most of those based on anonymous reviews (fortunately, none of the above commentators was one of them). The vast majority of anonymous reviews I received were well considered. While I would wish that all reviews were signed, I don't think we can summarily dismiss the fear that many would have of enmity and reprisal over a critical review. Some of these fears are likely justified. On more than one occasion, have I witnessed overly aggressive responses on the part of authors to anonymous reviews that I considered to be entirely fair and constructive in their criticisms. I do think we need to do all we can to discourage anonymous reviews, but it will be difficult to completely remove that choice from the process.

Print versus Electronic: Editors' Insights on the Costs and Benefits of Online Journals.

ERIC Educational Resources Information Center

Angell, Brian D.; Smith, Gabie E.

1998-01-01

Responses from 26 of 40 editors of electronic journals indicates that 57% were motivated to go online by creative possibilities; only 42% had existing print-journal counterparts; 34.6% felt they reach a broader or different audience online; and 50% felt online journals were less costly and had the advantage of speed of production. (SK)

Removal of water contaminants by nanoscale zero-valent iron immobilized in PAN-based oxidized membrane

NASA Astrophysics Data System (ADS)

Liu, Chunyi; Li, Xiang; Ma, Bomou; Qin, Aiwen; He, Chunju

2014-12-01

The functionalizing nanoporous polyacrylonitrile-based oxidized membrane (PAN-OM) firmly immobilized with highly reactive nanoscale zero-valent iron (NZVI) are successfully prepared via an innovative in situ synthesis method. Due to the formation of ladder structure, the PAN-OM present excellent thermal and chemical stabilities as a new carrier for the in-situ growth of NZVI via firm chelation and reduction action, respectively, which prevent the aggregation and release of NZVI. The developed NZVI-immobilized membrane present effective decolorizing efficiency to both anionic methyl blue and cationic methylene blue with a pseudo-first-order decay and degrading efficiency to trichloroethylene (TCE). The regeneration and stability results show that NZVI-immobilized membrane system can be regenerated without obvious performance reduction, which remain the reactivity after half a year storage period. These results suggest that PAN-based oxidized membrane immobilized with NZVI exhibit significant potential for environmental applications.

Wikipedia and medicine: quantifying readership, editors, and the significance of natural language.

PubMed

Heilman, James M; West, Andrew G

2015-03-04

Wikipedia is a collaboratively edited encyclopedia. One of the most popular websites on the Internet, it is known to be a frequently used source of health care information by both professionals and the lay public. This paper quantifies the production and consumption of Wikipedia's medical content along 4 dimensions. First, we measured the amount of medical content in both articles and bytes and, second, the citations that supported that content. Third, we analyzed the medical readership against that of other health care websites between Wikipedia's natural language editions and its relationship with disease prevalence. Fourth, we surveyed the quantity/characteristics of Wikipedia's medical contributors, including year-over-year participation trends and editor demographics. Using a well-defined categorization infrastructure, we identified medically pertinent English-language Wikipedia articles and links to their foreign language equivalents. With these, Wikipedia can be queried to produce metadata and full texts for entire article histories. Wikipedia also makes available hourly reports that aggregate reader traffic at per-article granularity. An online survey was used to determine the background of contributors. Standard mining and visualization techniques (eg, aggregation queries, cumulative distribution functions, and/or correlation metrics) were applied to each of these datasets. Analysis focused on year-end 2013, but historical data permitted some longitudinal analysis. Wikipedia's medical content (at the end of 2013) was made up of more than 155,000 articles and 1 billion bytes of text across more than 255 languages. This content was supported by more than 950,000 references. Content was viewed more than 4.88 billion times in 2013. This makes it one of if not the most viewed medical resource(s) globally. The core editor community numbered less than 300 and declined over the past 5 years. The members of this community were half health care providers and 85

Highlighting impact: Do editors' selections identify influential papers?

NASA Astrophysics Data System (ADS)

Antonoyiannakis, Manolis

A recent trend in scientific publishing is that journal editors highlight each week a select set among the papers published (usually) in their respective journals. The highlighted papers are deemed of higher quality, importance, or interest than the 'average' paper and feature prominently in the publishers' websites. We perform a citation analysis of the highlighted papers for a number of journals from various publishers in physics. By comparing the performance of highlighted papers relative to (a) typical papers and (b) highly cited papers in their source journals and in other journals in the field, we explore whether, and to what extent, the selection process at the time of publication identifies papers that will turn out to be influential. We discuss the broader implications for research assessment.

Dynamic calibration of pan-tilt-zoom cameras for traffic monitoring.

PubMed

Song, Kai-Tai; Tai, Jen-Chao

2006-10-01

Pan-tilt-zoom (PTZ) cameras have been widely used in recent years for monitoring and surveillance applications. These cameras provide flexible view selection as well as a wider observation range. This makes them suitable for vision-based traffic monitoring and enforcement systems. To employ PTZ cameras for image measurement applications, one first needs to calibrate the camera to obtain meaningful results. For instance, the accuracy of estimating vehicle speed depends on the accuracy of camera calibration and that of vehicle tracking results. This paper presents a novel calibration method for a PTZ camera overlooking a traffic scene. The proposed approach requires no manual operation to select the positions of special features. It automatically uses a set of parallel lane markings and the lane width to compute the camera parameters, namely, focal length, tilt angle, and pan angle. Image processing procedures have been developed for automatically finding parallel lane markings. Interesting experimental results are presented to validate the robustness and accuracy of the proposed method.

Debiasing the Distant Solar System Populations Using Pan-STARRS1

NASA Astrophysics Data System (ADS)

Lilly Schunova, Eva; Weryk, Robert J.; Chastel, Serge; Denneau, Larry; Jedicke, Robert; Wainscoat, Richard J.; Chambers, Kenneth C.

2017-10-01

We discuss our on-going effort to identify Trans-Neptunian Objects (TNOs) in the Pan-STARRS1 dataset, and to debias the size-frequency distributions (SFD) of detected TNO sub-populations in order to estimate their true population sizes. To measure our detection efficiency we used the model of Grav et al. (2011)[1], which includes Kuiper belt Objects (KBOs), Scattered Disc Objects (SDOs), and Centaurs. Our debiasing method accounts for the per-chip CCD sensitivity as well as CCD cell gaps. The search method for finding distant Solar System objects, which was developed for our initial work (Weryk et al., 2016)[2], led to discovery of 29 Centaurs, 243 KBOs and 61 SDOs from Pan-STARRS data spanning years 2010-2015. Our work is extended using more recent PS1 data.[1] Grav, T., et al. (2011), Publications of the Astronomical Society of Pacific, Volume 123, Issue 902, pp. 423.[2] Weryk, R.J., et al. (2016), eprint arXiv:1607.04895.

Coaxial Electrospinning and Characterization of Core-Shell Structured Cellulose Nanocrystal Reinforced PMMA/PAN Composite Fibers

PubMed Central

Li, Chao; Li, Qingde; Ni, Xiaohui; Liu, Guoxiang; Cheng, Wanli; Han, Guangping

2017-01-01

A modified coaxial electrospinning process was used to prepare composite nanofibrous mats from a poly(methyl methacrylate) (PMMA) solution with the addition of different cellulose nanocrystals (CNCs) as the sheath fluid and polyacrylonitrile (PAN) solution as the core fluid. This study investigated the conductivity of the as-spun solutions that increased significantly with increasing CNCs addition, which favors forming uniform fibers. This study discussed the effect of different CNCs addition on the morphology, thermal behavior, and the multilevel structure of the coaxial electrospun PMMA + CNCs/PAN composite nanofibers. A morphology analysis of the nanofibrous mats clearly demonstrated that the CNCs facilitated the production of the composite nanofibers with a core-shell structure. The diameter of the composite nanofibers decreased and the uniformity increased with increasing CNCs concentrations in the shell fluid. The composite nanofibrous mats had the maximum thermal decomposition temperature that was substantially higher than electrospun pure PMMA, PAN, as well as the core-shell PMMA/PAN nanocomposite. The BET (Brunauer, Emmett and Teller) formula results showed that the specific surface area of the CNCs reinforced core-shell composite significantly increased with increasing CNCs content. The specific surface area of the composite with 20% CNCs loading rose to 9.62 m2/g from 3.76 m2/g for the control. A dense porous structure was formed on the surface of the electrospun core-shell fibers. PMID:28772933

Pan-genome analysis of Aeromonas hydrophila, Aeromonas veronii and Aeromonas caviae indicates phylogenomic diversity and greater pathogenic potential for Aeromonas hydrophila.

PubMed

Ghatak, Sandeep; Blom, Jochen; Das, Samir; Sanjukta, Rajkumari; Puro, Kekungu; Mawlong, Michael; Shakuntala, Ingudam; Sen, Arnab; Goesmann, Alexander; Kumar, Ashok; Ngachan, S V

2016-07-01

Aeromonas species are important pathogens of fishes and aquatic animals capable of infecting humans and other animals via food. Due to the paucity of pan-genomic studies on aeromonads, the present study was undertaken to analyse the pan-genome of three clinically important Aeromonas species (A. hydrophila, A. veronii, A. caviae). Results of pan-genome analysis revealed an open pan-genome for all three species with pan-genome sizes of 9181, 7214 and 6884 genes for A. hydrophila, A. veronii and A. caviae, respectively. Core-genome: pan-genome ratio (RCP) indicated greater genomic diversity for A. hydrophila and interestingly RCP emerged as an effective indicator to gauge genomic diversity which could possibly be extended to other organisms too. Phylogenomic network analysis highlighted the influence of homologous recombination and lateral gene transfer in the evolution of Aeromonas spp. Prediction of virulence factors indicated no significant difference among the three species though analysis of pathogenic potential and acquired antimicrobial resistance genes revealed greater hazards from A. hydrophila. In conclusion, the present study highlighted the usefulness of whole genome analyses to infer evolutionary cues for Aeromonas species which indicated considerable phylogenomic diversity for A. hydrophila and hitherto unknown genomic evidence for pathogenic potential of A. hydrophila compared to A. veronii and A. caviae.

[Evaluation of a Neuropsychiatric Disorder: From PANDAS to PANS and CANS].

PubMed

Baytunca, Muharrem Burak; Donuk, Tuğba; Erermiş, Serpil

2016-01-01

PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections) syndrome is a disorder seen before adolescence that possesses an abrupt onset of obsessive-compulsive disorder symptoms and/or tics. Swedo and colleagues defined this disorder in 1998 as a syndrome related to Group A streptoccoccus (GAS) infection with neurological issues, such as motor hyperactivation and choreiform movements. The progress of the disorder may be described as wax-and-waning, apart from abrupt onset, and this relapse and remission course is associated with exacerbating infections, according to the creators of PANDAS syndrome. Ruling out of Rheumatoid Fever and Sydenham's Chorea was a necessity for making a proper diagnosis. Since the recognition of this syndrome, clinicians encountered many children who could not fulfill all 5 criteria, which must be met for PANDAS diagnosis. In addition, due to literature showing failure and lack of strong evidence of a major role of GAS, the newly-defined categories PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and CANS (Childhood Acute Neuropsychiatric Syndrome) were created to encompass those of "almost met" non-PANDAS cases. PANS and CANS include concurrent significant psychiatric symptoms with abrupt onset of OCD symptoms and/or tics but do not require identification of any infection agent, immune dysfunction, or enviromental precipitants. In this paper, we aimed to discuss PANS/ CANS, alterations of PANDAS, and diagnoses in which "almost met" PANDAS patients should be classified on the basis of a case who developed an abrupt onset of anxiety, obsessions, and vocal tics.

The pan-sharpening of satellite and UAV imagery for agricultural applications

NASA Astrophysics Data System (ADS)

Jenerowicz, Agnieszka; Woroszkiewicz, Malgorzata

2016-10-01

Remote sensing techniques are widely used in many different areas of interest, i.e. urban studies, environmental studies, agriculture, etc., due to fact that they provide rapid, accurate and information over large areas with optimal time, spatial and spectral resolutions. Agricultural management is one of the most common application of remote sensing methods nowadays. Monitoring of agricultural sites and creating information regarding spatial distribution and characteristics of crops are important tasks to provide data for precision agriculture, crop management and registries of agricultural lands. For monitoring of cultivated areas many different types of remote sensing data can be used- most popular are multispectral satellites imagery. Such data allow for generating land use and land cover maps, based on various methods of image processing and remote sensing methods. This paper presents fusion of satellite and unnamed aerial vehicle (UAV) imagery for agricultural applications, especially for distinguishing crop types. Authors in their article presented chosen data fusion methods for satellite images and data obtained from low altitudes. Moreover the authors described pan- sharpening approaches and applied chosen pan- sharpening methods for multiresolution image fusion of satellite and UAV imagery. For such purpose, satellite images from Landsat- 8 OLI sensor and data collected within various UAV flights (with mounted RGB camera) were used. In this article, the authors not only had shown the potential of fusion of satellite and UAV images, but also presented the application of pan- sharpening in crop identification and management.

Strengthened PAN-based carbon fibers obtained by slow heating rate carbonization

PubMed Central

Kim, Min-A; Jang, Dawon; Tejima, Syogo; Cruz-Silva, Rodolfo; Joh, Han-Ik; Kim, Hwan Chul; Lee, Sungho; Endo, Morinobu

2016-01-01

Large efforts have been made over the last 40 years to increase the mechanical strength of polyacrylonitrile (PAN)-based carbon fibers (CFs) using a variety of chemical or physical protocols. In this paper, we report a new method to increase CFs mechanical strength using a slow heating rate during the carbonization process. This new approach increases both the carbon sp3 bonding and the number of nitrogen atoms with quaternary bonding in the hexagonal carbon network. Theoretical calculations support a crosslinking model promoted by the interstitial carbon atoms located in the graphitic interlayer spaces. The improvement in mechanical performance by a controlled crosslinking between the carbon hexagonal layers of the PAN based CFs is a new concept that can contribute further in the tailoring of CFs performance based on the understanding of their microstructure down to the atomic scale. PMID:27004752

Strengthened PAN-based carbon fibers obtained by slow heating rate carbonization.

PubMed

Kim, Min-A; Jang, Dawon; Tejima, Syogo; Cruz-Silva, Rodolfo; Joh, Han-Ik; Kim, Hwan Chul; Lee, Sungho; Endo, Morinobu

2016-03-23

Large efforts have been made over the last 40 years to increase the mechanical strength of polyacrylonitrile (PAN)-based carbon fibers (CFs) using a variety of chemical or physical protocols. In this paper, we report a new method to increase CFs mechanical strength using a slow heating rate during the carbonization process. This new approach increases both the carbon sp(3) bonding and the number of nitrogen atoms with quaternary bonding in the hexagonal carbon network. Theoretical calculations support a crosslinking model promoted by the interstitial carbon atoms located in the graphitic interlayer spaces. The improvement in mechanical performance by a controlled crosslinking between the carbon hexagonal layers of the PAN based CFs is a new concept that can contribute further in the tailoring of CFs performance based on the understanding of their microstructure down to the atomic scale.

Panning for sperm gold: Isolation and purification of apyrene and eupyrene sperm from lepidopterans.

PubMed

Karr, Timothy L; Walters, James R

2015-08-01

We describe a simple and straightforward procedure for the purification and separation of apyrene and eupyrene forms of lepidopteran sperm. The procedure is generally applicable to both butterfly and moth species with results varying according to the relative amounts of sperm produced and size of sperm storage organs. The technique relies upon inherent differences between eupyene sperm bundles and free apyrene sperm morphology. These differences allow for separation of the sperm morphs by repeated "panning" of sperm bundles into the center of a plastic dish. The purified eupyrene sperm bundles can then be removed and apyrene sperm collected from the supernatant by centrifugation. Efficacy of the purification process was confirmed by light microscopy and gel electrophoresis of the resulting fractions. Both one- and two-dimensional gel electrophoresis identified significant protein differences between the fractions further suggesting that the panning procedure effectively separated eurpyrene from apyrene sperm. The panning procedure should provide a convenient and accessible technique for further studies of sperm biology in lepidopterans. Copyright © 2015 Elsevier Ltd. All rights reserved.

Measurements of postnatal growth of the skull of Pan troglodytes verus using lateral cephalograms.

PubMed

Arnold, Wolfgang H; Protsch von Zieten, Reiner; Schmidt, Ekehard

2003-03-01

The postnatal growth of the viscerocranium in relation to the neurocranium of Pan troglodytes verus has been investigated using standardized lateral cephalograms. Sex and age were determined on the basis of cranial morphology and the skulls were divided into four age groups: infantile, juvenile, subadult and adult. The cephalograms were traced on transparencies and specific anatomical landmarks were identified for the measurement of lines angles and the area of the neurocranium and viscerocranium. The results showed that the skull of Pan troglodytes verus exhibits klinorhynchy. During postnatal growth it develops towards airorhynchy, but never shows true airorhynchy. In the infantile age group the measured area of the neurocranium is larger than that of the viscerocranium. The measured area of the viscerocranium increases until adulthood and is larger than that of the neurocranium in the subadult and adult group. From the results we conclude that in Pan troglodytes verus growth of the neurocranium seizes early in juvenile individuals, whereas the viscerocranium grows until adulthood. This may reflect an adaptation to the masticatory system.

Demonstrating a Lack of Reactivity Using a Teflon-Coated Pan.

ERIC Educational Resources Information Center

Richmond, Thomas G.

1995-01-01

Illustrates the chemical resistance of polytetrafluoroethene to mineral acids using an ordinary Teflon-coated frying pan. The demonstration can also be used to lead to a discussion of the long lifetimes of fluorocarbons and chlorofluorocarbons in the atmosphere and their roles in the breakdown of the ozone layer. (AIM)

24. Roof detail from liftbed truck, showing pan roof above ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. Roof detail from lift-bed truck, showing pan roof above breezeway, with sawn redwood trim, tube-type drains; note missing rain gutter at roof edge, deteriorated condition of slates; view to south, 90mm lens. - Southern Pacific Depot, 559 El Camino Real, San Carlos, San Mateo County, CA

Patterns of mandibular variation in Pan and Gorilla and implications for African ape taxonomy.

PubMed

Taylor, Andrea B; Groves, Colin P

2003-05-01

Pan and Gorilla taxonomy is currently in a state of flux, with the number of existing species and subspecies of common chimpanzee and gorilla having been recently challenged. While Pan and Gorilla systematics have been evaluated on the basis of craniometric and odontometric data, only a handful of studies have evaluated multivariate craniometric variation within P. troglodytes, and none have evaluated in detail mandibular variation in either P. troglodytes or Gorilla gorilla. In this paper, we examine ontogenetic and adult mandibular variation in Pan and Gorilla. We test the hypothesis that patterns and degrees of mandibular variation in Pan and Gorilla closely correspond to those derived from previous analyses of craniometric variation. We then use these data to address some current issues surrounding Pan and Gorilla taxonomy. Specifically, we evaluate the purported distinctiveness of P.t. verus from the other two subspecies of Pan troglodytes, and the recent proposals to recognize Nigerian gorillas as a distinct subspecies, Gorilla gorilla diehli, and to acknowledge mountain and lowland gorillas as two separate species. Overall, patterns and degrees of multivariate mandibular differentiation parallel those obtained previously for the cranium and dentition. Thus, differences among the three conventionally recognized gorilla subspecies are somewhat greater than among subspecies of common chimpanzees, but differences between P. paniscus and P. troglodytes are greater than those observed between any gorilla subspecies. In this regard, the mandible does not appear to be more variable, or of less taxonomic value, than the face and other parts of the cranium. There are, however, some finer differences in the pattern and degree of morphological differentiation in Pan and Gorilla, both with respect to cranial and dental morphology, and in terms of the application and manner of size adjustment. Mandibular differentiation supports the conventional separation of bonobos from

Prediction of Pan-Specific B-Cell Epitopes From Nucleocapsid Protein of Hantaviruses Causing Hantavirus Cardiopulmonary Syndrome.

PubMed

Kalaiselvan, Sagadevan; Sankar, Sathish; Ramamurthy, Mageshbabu; Ghosh, Asit Ranjan; Nandagopal, Balaji; Sridharan, Gopalan

2017-08-01

Hantaviruses are emerging viral pathogens that causes hantavirus cardiopulmonary syndrome (HCPS) in the Americas, a severe, sometimes fatal, respiratory disease in humans with a case fatality rate of ≥50%. IgM and IgG-based serological detection methods are the most common approaches used for laboratory diagnosis of hantaviruses. Such emerging viral pathogens emphasizes the need for improved rapid diagnostic devices and vaccines incorporating pan-specific epitopes of genotypes. We predicted linear B-cell epitopes for hantaviruses that are specific to genotypes causing HCPS in humans using in silico prediction servers. We modeled the Andes and Sin Nombre hantavirus nucleocapsid protein to locate the identified epitopes. Based on the mean percent prediction probability score, epitope IMASKSVGS/TAEEKLKKKSAF was identified as the best candidate B-cell epitope specific for hantaviruses causing HCPS. Promiscuous epitopes were identified in the C-terminal of the protein. Our study for the first time has reported pan-specific B-cell epitopes for developing immunoassays in the detection of antibodies to hantaviruses causing HCPS. Identification of epitopes with pan-specific recognition of all genotypes causing HCPS could be valuable for the development of immunodiagnositic tools toward pan-detection of hantavirus antibodies in ELISA. J. Cell. Biochem. 118: 2320-2324, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Postmarketing surveillance: perspectives of a journal editor.

PubMed

Gelenberg, A J

1993-01-01

In the absence of a systematic monitoring program for drugs newly approved by the Food and Drug Administration (FDA), reports in clinical journals provide a legitimate forum for disseminating information about unexpected pharmacologic events. A journal editor bears the responsibility for publishing educated clinical observations that meet standards of scientific rigor while not giving premature credibility to chance and dubious reports of side effects of new drugs. Often this responsibility involves overcoming the fear of bad publicity and withstanding pressures from pharmaceutical companies to print only positive information about new products. Published preliminary observations may contribute to the problem of product liability, but they also generate testable hypotheses and healthy debate. If hypotheses later prove to be incorrect, they can be refuted by systematic studies and clarified in reviews and editorials. Our goal of effective education will be reached not by self-censorship but by scientific openness.

Soda pans of the Pannonian steppe harbor unique bacterial communities adapted to multiple extreme conditions.

PubMed

Szabó, Attila; Korponai, Kristóf; Kerepesi, Csaba; Somogyi, Boglárka; Vörös, Lajos; Bartha, Dániel; Márialigeti, Károly; Felföldi, Tamás

2017-05-01

Soda pans of the Pannonian steppe are unique environments regarding their physical and chemical characteristics: shallowness, high turbidity, intermittent character, alkaline pH, polyhumic organic carbon concentration, hypertrophic condition, moderately high salinity, sodium and carbonate ion dominance. The pans are highly productive environments with picophytoplankton predominance. Little is known about the planktonic bacterial communities inhabiting these aquatic habitats; therefore, amplicon sequencing and shotgun metagenomics were applied to reveal their composition and functional properties. Results showed a taxonomically complex bacterial community which was distinct from other soda lakes regarding its composition, e.g. the dominance of class Alphaproteobacteria was observed within phylum Proteobacteria. The shotgun metagenomic analysis revealed several functional gene components related to the harsh and at the same time hypertrophic environmental conditions, e.g. proteins involved in stress response, transport and hydrolase systems targeting phytoplankton-derived organic matter. This is the first detailed report on the indigenous planktonic bacterial communities coping with the multiple extreme conditions present in the unique soda pans of the Pannonian steppe.

Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution.

PubMed

Zihlman, Adrienne L; Bolter, Debra R

2015-06-16

The human body has been shaped by natural selection during the past 4-5 million years. Fossils preserve bones and teeth but lack muscle, skin, fat, and organs. To understand the evolution of the human form, information about both soft and hard tissues of our ancestors is needed. Our closest living relatives of the genus Pan provide the best comparative model to those ancestors. Here, we present data on the body composition of 13 bonobos (Pan paniscus) measured during anatomical dissections and compare the data with Homo sapiens. These comparative data suggest that both females and males (i) increased body fat, (ii) decreased relative muscle mass, (iii) redistributed muscle mass to lower limbs, and (iv) decreased relative mass of skin during human evolution. Comparison of soft tissues between Pan and Homo provides new insights into the function and evolution of body composition.

A Regional, Integrated Monitoring System for the Hydrology of the Pan-Arctic Land Mass

NASA Technical Reports Server (NTRS)

Serreze, Mark; Barry, Roger; Nolin, Anne; Armstrong, Richard; Zhang, Ting-Jung; Vorosmarty, Charles; Lammers, Richard; Frolking, Steven; Bromwich, David; McDonald, Kyle

2005-01-01

Work under this NASA contract developed a system for monitoring and historical analysis of the major components of the pan-Arctic terrestrial water cycle. It is known as Arctic-RIMS (Regional Integrated Hydrological Monitoring System for the Pan-Arctic Landmass). The system uses products from EOS-era satellites, numerical weather prediction models, station records and other data sets in conjunction with an atmosphere-land surface water budgeting scheme. The intent was to compile operational (at 1-2 month time lags) gridded fields of precipitation (P), evapotranspiration (ET), P-ET, soil moisture, soil freeze/thaw state, active layer thickness, snow extent and its water equivalent, soil water storage, runoff and simulated discharge along with estimates of non-closure in the water budget. Using "baseline" water budgeting schemes in conjunction with atmospheric reanalyses and pre-EOS satellite data, water budget fields were conjunction with atmospheric reanalyses and pre-EOS satellite data, water budget fields were compiled to provide historical time series. The goals as outlined in the original proposal can be summarized as follows: 1) Use EOS data to compile hydrologic products for the pan-Arctic terrestrial regions including snowcover/snow water equivalent (SSM/A MODIS, AMSR) and near-surface freeze/thaw dynamics (Sea Winds on QuikSCAT and ADEOS I4 SSMI and AMSR). 2) Implement Arctic-RIMS to use EOS data streams, allied fields and hydrologic models to produce allied outputs that fully characterize pan-Arctic terrestrial and aerological water budgets. 3) Compile hydrologically-based historical products providing a long-term baseline of spatial and temporal variability in the water cycle.

Near Field Cosmology with the Pan-Andromeda Archaeological Survey

NASA Astrophysics Data System (ADS)

McConnachie, A. W.; PAndAS Collaboration

2012-08-01

I describe the Pan-Andromeda Archaeological Survey (PAndAS), and discuss several recent science highlights, including studies of its dwarf satellite systems, its stellar halo, and correlations with the HI content. I also discuss the need for a large scale, wide field, multi-object spectroscopic survey, such as the type made possible with the proposed Next Generation Canada-France-Hawaii Telescope (NG-CFHT).

Analyses of the soil surface dynamic of South African Kalahari salt pans based on hyperspectral and multitemporal data

NASA Astrophysics Data System (ADS)

Milewski, Robert; Chabrillat, Sabine; Behling, Robert; Mielke, Christian; Schleicher, Anja Maria; Guanter, Luis

2016-04-01

The consequences of climate change represent a major threat to sustainable development and growth in Southern Africa. Understanding the impact on the geo- and biosphere is therefore of great importance in this particular region. In this context the Kalahari salt pans (also known as playas or sabkhas) and their peripheral saline and alkaline habitats are an ecosystem of major interest. They are very sensitive to environmental conditions, and as thus hydrological, mineralogical and ecological responses to climatic variations can be analysed. Up to now the soil composition of salt pans in this area have been only assessed mono-temporally and on a coarse regional scale. Furthermore, the dynamic of the salt pans, especially the formation of evaporites, is still uncertain and poorly understood. High spectral resolution remote sensing can estimate evaporite content and mineralogy of soils based on the analyses of the surface reflectance properties within the Visible-Near InfraRed (VNIR 400-1000 nm) and Short-Wave InfraRed (SWIR 1000-2500 nm) regions. In these wavelength regions major chemical components of the soil interact with the electromagnetic radiation and produce characteristic absorption features that can be used to derive the properties of interest. Although such techniques are well established for the laboratory and field scale, the potential of current (Hyperion) and upcoming spaceborne sensors such as EnMAP for quantitative mineralogical and salt spectral mapping is still to be demonstrated. Combined with hyperspectral methods, multitemporal remote sensing techniques allow us to derive the recent dynamic of these salt pans and link the mineralogical analysis of the pan surface to major physical processes in these dryland environments. In this study we focus on the analyses of the Namibian Omongwa salt pans based on satellite hyperspectral imagery and multispectral time-series data. First, a change detection analysis is applied using the Iterative

A Portable Burn Pan for the Disposal of Excess Propellants

DTIC Science & Technology

2015-11-01

National Guard Bureau; John Hunt , formerly at Camp Grayling; Jo Anderson, formerly at Ft. Indiantown Gap; and Steve Thurmond, formerly at US Army Alaska...Finally at CRREL, Marianne Walsh, Charlie Smith, Tommie Hall, Matt Bigl, Chris Donnelly, and Jordan Hodge all played major roles in the success of the burn pan.

PanMetaDocs - A tool for collecting and managing the long tail of "small science data"

NASA Astrophysics Data System (ADS)

Klump, J.; Ulbricht, D.

2011-12-01

In the early days of thinking about cyberinfrastructure the focus was on "big science data". Today, the challenge is not anymore to store several terabytes of data, but to manage data objects in a way that facilitates their re-use. Key to re-use by a user as a data consumer is proper documentation of the data. Also, data consumers need discovery metadata to find the data they need and they need descriptive metadata to be able to use the data they retrieved. Thus, data documentation faces the challenge to extensively and completely describe these objects, hold the items easily accessible at a sustainable cost level. However, data curation and documentation do not rank high in the everyday work of a scientist as a data producer. Data producers are often frustrated by being asked to provide metadata on their data over and over again, information that seemed very obvious from the context of their work. A challenge to data archives is the wide variety of metadata schemata in use, which creates a number of maintenance and design challenges of its own. PanMetaDocs addresses these issues by allowing an uploaded files to be described by more than one metadata object. PanMetaDocs, which was developed from PanMetaWorks, is a PHP based web application that allow to describe data with any xml-based metadata schema. Its user interface is browser based and was developed to collect metadata and data in collaborative scientific projects situated at one or more institutions. The metadata fields can be filled with static or dynamic content to reduce the number of fields that require manual entries to a minimum and make use of contextual information in a project setting. In the development of PanMetaDocs the business logic of panMetaWorks is reused, except for the authentication and data management functions of PanMetaWorks, which are delegated to the eSciDoc framework. The eSciDoc repository framework is designed as a service oriented architecture that can be controlled through a

Community Air Monitoring for Pesticide Drift Using Pesticide Action Network's (PAN) Drift Catcher

NASA Astrophysics Data System (ADS)

Marquez, E.

2016-12-01

Community air monitoring projects for pesticides in the air have been conducted by PAN in collaboration with community members and locally based groups engaged around pesticide issues. PAN is part of an international network working to promote a just, thriving food system and replace the use of hazardous pesticides with ecologically sound alternatives. The Drift Catcher is an air-monitoring device with a design based on the California Air Resource Board's air monitoring equipment, and has been used in community-based projects in 11 states. Observations of pesticide drift made by community members cannot always be confirmed by regulatory agencies—if an inspection is made hours or days after a drift incident, the evidence may no longer be present. The Drift Catcher makes it possible to collect scientific evidence of pesticide drift in areas where people live, work, and play. One of the most recent Drift Catcher projects was done in California, in partnership with the Safe Strawberry Coalition and led by the statewide coalition Californians for Pesticide Reform. The data were used to support a call for stronger mitigation rules for the fumigant chloropicrin and to support a campaign asking for stronger pesticide rules to protect children attending school in close proximity to agricultural fields. The Drift Catcher data are used by organizers and community members to engage policymakers with the intention of making policy change on a local and/or statewide level. On the national level, PAN's Drift Catcher data has helped win regulatory recognition of volatilization drift for pesticides other than fumigants. Lessons learned from conducting community-based research projects will also be discussed. PAN is also currently assessing other community-based monitoring tools, such as community surveys and drift questionnaires that may allow communities to collect data that can also support the campaign work.

Making the First Cut: An Analysis of Academic Medicine Editors' Reasons for Not Sending Manuscripts Out for External Peer Review.

PubMed

Meyer, Holly S; Durning, Steven J; Sklar, David P; Maggio, Lauren A

2018-03-01

Manuscripts submitted to Academic Medicine (AM) undergo an internal editor review to determine whether they will be sent for external peer review. Increasingly, manuscripts are rejected at this early stage. This study seeks to inform scholars about common reasons for internal editor review rejections, increase transparency of the process, and provide suggestions for improving submissions. A mixed-methods approach was used to retrospectively analyze editors' free-text comments. Descriptive content analysis was performed of editors' comments for 369 manuscripts submitted between December 2014 and December 2015, and rejected prior to external peer review from AM. Comments were analyzed, categorized, and counted for explicit reasons for rejection. Nine categories of rejection reasons were identified: ineffective study question and/or design (338; 92%); suboptimal data collection process (180; 49%); weak discussion and/or conclusions (139; 37%); unimportant or irrelevant topic to the journal's mission (137; 37%); weak data analysis and/or presentation of results (120; 33%); text difficult to follow, to understand (89; 24%); inadequate or incomplete introduction (67; 18%); other publishing considerations (42; 11%); and issues with scientific conduct (20; 5%). Manuscripts had, on average, three or more reasons for rejection. Findings suggest that clear identification of a research question that is addressed by a well-designed study methodology on a topic aligned with the mission of the journal would address many of the problems that lead to rejection through the internal review process. The findings also align with research on external peer review.

An expert opinion on PANDAS/PANS: highlights and controversies.

PubMed

Chiarello, Francesca; Spitoni, Silvia; Hollander, Eric; Matucci Cerinic, Marco; Pallanti, Stefano

2017-06-01

'Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections' (PANDAS) identified a unique subgroup of patients with abrupt onset of obsessive compulsive disorder (OCD) symptoms clinically related to Streptococcus infection and accompanied by neuropsychological and motor symptoms. After almost 20 years, PANDAS has not been accepted as distinct disorder and new criteria for paediatric acute-onset neuropsychiatric syndrome (PANS) have been replaced it, highlighting the fact that several agents rather than only Streptococcus might be involved. Extensive review of the PANDAS/PANS literature was performed on PubMed. Although antibiotics have been reported to be effective for acute and prophylactic phases in several uncontrolled studies and non-steroidal anti-inflammatory drugs (NSAID) are used during exacerbations, clinical multicenter trials are still missing. Selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioural therapy (CBT) are still the first line of recommendation for acute onset OCD spectrum. Immunological therapies should be restricted to a few cases. While PANDAS has found no confirmation as a distinct syndrome, and it is not presented in DSM-5, patients with acute onset OCD spectrum, neurocognitive and motor symptoms should be evaluated for inflammatory, infective, immunological and metabolic abnormalities with a comprehensive diagnostic algorithm.

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours | Office of Cancer Genomics

Cancer.gov

Analysis of molecular aberrations across multiple cancer types, known as pan-cancer analysis, identifies commonalities and differences in key biological processes that are dysregulated in cancer cells from diverse lineages. Pan-cancer analyses have been performed for adult1–4 but not paediatric cancers, which commonly occur in developing mesodermic rather than adult epithelial tissues5.

Martin Stutzmann: Editor, Teacher, Scientist and Friend

NASA Astrophysics Data System (ADS)

Cardona, Manuel

2005-02-01

On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

An International Call for Democratizing the Academic Journal Culture from a Community of Editors

ERIC Educational Resources Information Center

Mullen, Carol A.; Pryor, Caroline R.; Browne-Ferrigno, Tricia; Harris, Sandra L.

2013-01-01

In our reflective essay from our multiple perspectives as journal editors, peer reviewers, and published authors, we present ideas about editorial support, democracy, and innovation in the publishing process. As four tenured professors who work in universities in the states of Illinois, Virginia, Texas, and Kentucky, we are a community of editors…

How Well Do Americans Know Geography? "National Geographic" Editor Discusses Meaning for Schools (Interview).

ERIC Educational Resources Information Center

Koerner, Thomas

1987-01-01

Gilbert Grosvenor, editor of "National Geographic," is interviewed about the importance of geography for Americans. He claims our lack of geographic knowledge impedes our ability to act and compete in the world market as a world power and points out that geographic ignorance extends to people employed at high levels of government. (MD)

Results from the Pan-STARRS1 Sky Surveys

NASA Astrophysics Data System (ADS)

Chambers, Kenneth C.; PS1 Science Consortium

2015-01-01

Results from the Pan-STARRS1 Sky Surveys spanning the field of astronomy from Near Earth Objects to Cosmology will be presented.Scientific highlights from the PS1 Sky Surveys include: the photometric and astrometric reference catalog with unprecedented size, accuracy, and dynamic range discovery of 1200 NEO's, 120 PHAs, 60 comets; discovery of rotational break up as the origin of catastrophic disruption of solar system bodies; first free floating planet PSO 318-22 and other ultra-cool objects; first 3-dimensional map of dust in the Milky Way; new distances to molecular clouds; new stellar streams in the Milky Way and new globular clusters; new satellite galaxies of M31; eclipsing binaries in M31 - an important step for the distance ladder; micro-lensing events and other variables in M31: super-luminous and under-luminous stellar explosions; first clear tidal disruption of star by supermassive black hole; many new high redshift quasars; and a new determination of the dark energy equation of state from SnIa photometry.The nearly 4 year Pan-STARRS1 Science Mission has now completed. The reprocessing of the entire data set is underway. The Public Release of the entire image, catalog and metadata set of the PS1 Sky Surveys is scheduled for April 1, 2015 from the STScI MAST archive. It is expected that a great many more scientific results will come with community access to the data set.The Pan-STARRS1 Surveys have been made possible through contributions of the Institute for Astronomy of the University of Hawaii; the Max-Planck Society and its participating institutes: the Max Planck Institute for Astronomy, Heidelberg and the Max Planck Institute for Extraterrestrial Physics, Garching; The Johns Hopkins University; Durham University; the University of Edinburgh; Queen's University Belfast; the Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated; the National Central University of Taiwan; the Space Telescope

Learning Low-Rank Decomposition for Pan-Sharpening With Spatial-Spectral Offsets.

PubMed

Yang, Shuyuan; Zhang, Kai; Wang, Min

2017-08-25

Finding accurate injection components is the key issue in pan-sharpening methods. In this paper, a low-rank pan-sharpening (LRP) model is developed from a new perspective of offset learning. Two offsets are defined to represent the spatial and spectral differences between low-resolution multispectral and high-resolution multispectral (HRMS) images, respectively. In order to reduce spatial and spectral distortions, spatial equalization and spectral proportion constraints are designed and cast on the offsets, to develop a spatial and spectral constrained stable low-rank decomposition algorithm via augmented Lagrange multiplier. By fine modeling and heuristic learning, our method can simultaneously reduce spatial and spectral distortions in the fused HRMS images. Moreover, our method can efficiently deal with noises and outliers in source images, for exploring low-rank and sparse characteristics of data. Extensive experiments are taken on several image data sets, and the results demonstrate the efficiency of the proposed LRP.

Application of thermal model for pan evaporation to the hydrology of a defined medium, the sponge

NASA Technical Reports Server (NTRS)

Trenchard, M. H.; Artley, J. A. (Principal Investigator)

1981-01-01

A technique is presented which estimates pan evaporation from the commonly observed values of daily maximum and minimum air temperatures. These two variables are transformed to saturation vapor pressure equivalents which are used in a simple linear regression model. The model provides reasonably accurate estimates of pan evaporation rates over a large geographic area. The derived evaporation algorithm is combined with precipitation to obtain a simple moisture variable. A hypothetical medium with a capacity of 8 inches of water is initialized at 4 inches. The medium behaves like a sponge: it absorbs all incident precipitation, with runoff or drainage occurring only after it is saturated. Water is lost from this simple system through evaporation just as from a Class A pan, but at a rate proportional to its degree of saturation. The contents of the sponge is a moisture index calculated from only the maximum and minium temperatures and precipitation.

Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution

PubMed Central

Zihlman, Adrienne L.; Bolter, Debra R.

2015-01-01

The human body has been shaped by natural selection during the past 4–5 million years. Fossils preserve bones and teeth but lack muscle, skin, fat, and organs. To understand the evolution of the human form, information about both soft and hard tissues of our ancestors is needed. Our closest living relatives of the genus Pan provide the best comparative model to those ancestors. Here, we present data on the body composition of 13 bonobos (Pan paniscus) measured during anatomical dissections and compare the data with Homo sapiens. These comparative data suggest that both females and males (i) increased body fat, (ii) decreased relative muscle mass, (iii) redistributed muscle mass to lower limbs, and (iv) decreased relative mass of skin during human evolution. Comparison of soft tissues between Pan and Homo provides new insights into the function and evolution of body composition. PMID:26034269

EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

NASA Astrophysics Data System (ADS)

Corkum, Paul

2011-01-01

As a journal that reports advances in atomic, molecular and optical science (AMO), Journal of Physics B: Atomic, Molecular and Optical Physics (J. Phys. B) provides the AMO research community with three unique fora: topical reviews, tutorials and special issues. Developed under the leadership of editor Jan Michael Rost and his Editorial Board, these sections have cemented J. Phys. B's reputation as a major journal showcasing the AMO community's advances. For me, an AMO scientist, it is therefore a special pleasure to be entrusted with continuing the tradition of excellence established by Jan Michael and the Editorial Board. I intend to build on this foundation by ensuring that the journal makes full use of these tools. Topical reviews: a unique focus When J. Phys. B becomes the first journal you turn to for initial reviews about important emerging areas in your field, we as an Editorial Board will have succeeded. To us, a topical review is different from a traditional review—a topical review focuses on emerging sub-fields of AMO physics. Its function is to alert and educate our readers about emerging opportunities. Topical reviews can also serve a closely related function for readers: keeping us up-to-date with critical technologies that lie slightly outside our own fields, such as advances in free-electron lasers science, (which will surely affect our field). Our overall goal is to make your research more productive because of the topical reviews you read within the journal. Tutorials J. Phys. B tutorials are aimed at graduate students or researchers venturing into a new field. Just as in my own research group I encourage all graduate students to write their theses in a way that will be useful to both future graduate students and the larger community beyond my group, J. Phys. B has designed tutorials to fill this function on the journal scale. Thus, tutorial authors are able to write in greater depth than can be included in a paper in nature, science or in the

PlantPAN 2.0: an update of plant promoter analysis navigator for reconstructing transcriptional regulatory networks in plants.

PubMed

Chow, Chi-Nga; Zheng, Han-Qin; Wu, Nai-Yun; Chien, Chia-Hung; Huang, Hsien-Da; Lee, Tzong-Yi; Chiang-Hsieh, Yi-Fan; Hou, Ping-Fu; Yang, Tien-Yi; Chang, Wen-Chi

2016-01-04

Transcription factors (TFs) are sequence-specific DNA-binding proteins acting as critical regulators of gene expression. The Plant Promoter Analysis Navigator (PlantPAN; http://PlantPAN2.itps.ncku.edu.tw) provides an informative resource for detecting transcription factor binding sites (TFBSs), corresponding TFs, and other important regulatory elements (CpG islands and tandem repeats) in a promoter or a set of plant promoters. Additionally, TFBSs, CpG islands, and tandem repeats in the conserve regions between similar gene promoters are also identified. The current PlantPAN release (version 2.0) contains 16 960 TFs and 1143 TF binding site matrices among 76 plant species. In addition to updating of the annotation information, adding experimentally verified TF matrices, and making improvements in the visualization of transcriptional regulatory networks, several new features and functions are incorporated. These features include: (i) comprehensive curation of TF information (response conditions, target genes, and sequence logos of binding motifs, etc.), (ii) co-expression profiles of TFs and their target genes under various conditions, (iii) protein-protein interactions among TFs and their co-factors, (iv) TF-target networks, and (v) downstream promoter elements. Furthermore, a dynamic transcriptional regulatory network under various conditions is provided in PlantPAN 2.0. The PlantPAN 2.0 is a systematic platform for plant promoter analysis and reconstructing transcriptional regulatory networks. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Ratosa playa lake in southern Spain. Karst pan or compound sink?

PubMed

Rodríguez-Rodríguez, Miguel; Martos-Rosillo, Sergio; Pedrera, Antonio; Benavente-Herrera, José

2015-04-01

In Andalusia (Spain), there are more than 45 semiarid playa lakes protected as natural reserves and related to karstic outcrops. Some of them are located over regional karstic aquifers and have internal drainage networks with sporadic surface outlets, such as sinkholes (compound sinks), but the majority of such playas have no internal drainage systems, so the only water output is evaporation (karst pans). Karst pans are perched and disconnected from the groundwater system. The fact that the Ratosa playa lake is partially located over a karstic Sierra, as well as other hydromorphological observations, it is suggested that the system could be of a compound type, but a detailed hydrogeological analysis showed that the playa is disconnected from the aquifer, so it is in fact a karst pan. Once the hydrological functioning had been established, a monthly water balance for a 10-year period (1998-2008), enabled us to reproduce the evolution of the water level of the playa lake. Estimations of runoff were carried out by a soil water estimate for a water holding capacity in the soil of 191 mm. Results show a good correlation (>90%) after calibration with the time series of water level in the lake for the same period confirming geological observations. Our results highlight that this water body is extremely vulnerable to hydrological alterations of its watershed caused by human activities, particularly those related to land-use change for agriculture. For this reason, we propose a new protection zone, based on hydrological knowledge, instead of the present Peripheral Area of Protection.

ReprDB and panDB: minimalist databases with maximal microbial representation.

PubMed

Zhou, Wei; Gay, Nicole; Oh, Julia

2018-01-18

Profiling of shotgun metagenomic samples is hindered by a lack of unified microbial reference genome databases that (i) assemble genomic information from all open access microbial genomes, (ii) have relatively small sizes, and (iii) are compatible to various metagenomic read mapping tools. Moreover, computational tools to rapidly compile and update such databases to accommodate the rapid increase in new reference genomes do not exist. As a result, database-guided analyses often fail to profile a substantial fraction of metagenomic shotgun sequencing reads from complex microbiomes. We report pipelines that efficiently traverse all open access microbial genomes and assemble non-redundant genomic information. The pipelines result in two species-resolution microbial reference databases of relatively small sizes: reprDB, which assembles microbial representative or reference genomes, and panDB, for which we developed a novel iterative alignment algorithm to identify and assemble non-redundant genomic regions in multiple sequenced strains. With the databases, we managed to assign taxonomic labels and genome positions to the majority of metagenomic reads from human skin and gut microbiomes, demonstrating a significant improvement over a previous database-guided analysis on the same datasets. reprDB and panDB leverage the rapid increases in the number of open access microbial genomes to more fully profile metagenomic samples. Additionally, the databases exclude redundant sequence information to avoid inflated storage or memory space and indexing or analyzing time. Finally, the novel iterative alignment algorithm significantly increases efficiency in pan-genome identification and can be useful in comparative genomic analyses.